Omeprazole (trade name Prilosec)

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16 Diseases Researched for Omeprazole (trade name Prilosec)

Name	AC	CK
Acid Reflux	1	10
Brain: Oxidative Stress	1	10
Cognitive Decline/Dysfunction	1	10
Constipation	1	10
Drug-Induced Toxicity	1	10
Dyspepsia	1	10
Gastroesophageal Reflux	1	10
Magnesium Deficiency	1	10
Nephritis	1	10
Seizures	1	10
Vitamin C Deficiency	1	10
Gastric Cancer	2	4
Animal Diseases: Scrapie	1	2
Dysbiosis	1	2
Prion Diseases	1	2
Scrapie	1	2

3 Adverse Pharmacological Actions Researched for Omeprazole (trade name Prilosec)

Name	AC	CK
Gastrotoxic	1	10
Neurotransmitter Interference	1	10
Carcinogen	1	2

Research Articles 11
Cumulative Knowledge Score 17
Overall Research Rating GOOD

View the Evidence:
11 Abstracts with Omeprazole (trade name Prilosec) Research

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Long-term use of omeprazole is suggested to induce an oxidative stress condition, which causes neurotoxicity and cognitive decline.Feb 21, 2021

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Pubmed Data : J Pharm Pharmacol. 2021 Feb 22. Epub 2021 Feb 22. PMID: 33793790

Article Published Date : Feb 21, 2021

Study Type : Human Study

Additional Links

Diseases : Brain: Oxidative Stress, Cognitive Decline/Dysfunction

Problem Substances : Omeprazole (trade name Prilosec)

Adverse Pharmacological Actions : Neurotransmitter Interference

[+]

Omeprazole has been linked to interstitial nephritis.May 01, 2010

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Pubmed Data : Br J Clin Pharmacol. 2010 May;69(5):516-9. PMID: 20573087

Article Published Date : May 01, 2010

Study Type : Human Study

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Diseases : Drug-Induced Toxicity , Nephritis

Problem Substances : Omeprazole (trade name Prilosec)

[+]

Omeprazole treatment have caused considerable changes in stool culture results.Feb 28, 2017

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Pubmed Data : Clin Res Hepatol Gastroenterol. 2017 Mar 1. Epub 2017 Mar 1. PMID: 28258834

Article Published Date : Feb 28, 2017

Study Type : Human Study

Additional Links

Additional Keywords : Risk Factors

Problem Substances : Omeprazole (trade name Prilosec), Proton-Pump Inhibitors

Adverse Pharmacological Actions : Gastrotoxic

[+]

Proton pump inhibitors reduce the bioavailability of dietary vitamin C.Sep 15, 2005

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Pubmed Data : Aliment Pharmacol Ther. 2005 Sep 15;22(6):539-45. PMID: 16167970

Article Published Date : Sep 15, 2005

Study Type : Human Study

Additional Links

Diseases : Vitamin C Deficiency

Additional Keywords : Drug: Omeprazole

Problem Substances : Omeprazole (trade name Prilosec), Proton-Pump Inhibitors

[+]

Proton-pump inhibitor therapy induces acid-related symptoms in healthy volunteers after withdrawal of therapy, indicating the drug causes rebound acid hypersecretion (RAHS).Jul 01, 2009

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Pubmed Data : Gastroenterology. 2009 Jul;137(1):80-7, 87.e1. Epub 2009 Apr 10. PMID: 19362552

Article Published Date : Jul 01, 2009

Study Type : Human Study

Additional Links

Diseases : Acid Reflux, Dyspepsia

Additional Keywords : Drug: Omeprazole

Problem Substances : Omeprazole (trade name Prilosec)

[+]

Severe hypomagnesaemia and subsequent seizure has been reported in long-term users of proton-pump inhibitors.Aug 01, 2008

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Pubmed Data : Clin Endocrinol (Oxf). 2008 Aug;69(2):338-41. Epub 2008 Jan 23. PMID: 18221401

Article Published Date : Aug 01, 2008

Study Type : Human Study

Additional Links

Diseases : Magnesium Deficiency, Seizures

Additional Keywords : Drug: Omeprazole

Problem Substances : Omeprazole (trade name Prilosec)

[+]

Treatment of functional constipation by Psyllium seed in patients with gastroesophageal reflux disease leads to improvement and lessens its recurrence.Dec 31, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Evid Based Integr Med. 2018 Jan-Dec;23:2515690X18763294. PMID: 29607676

Article Published Date : Dec 31, 2017

Study Type : Human Study

Additional Links

Substances : Psyllium

Diseases : Constipation, Gastroesophageal Reflux

Additional Keywords : Superiority of Natural Substances versus Drugs

Problem Substances : Omeprazole (trade name Prilosec)

[+]

Acid blockers increase the risk of prion infection in mice. Sep 22, 2011

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Pubmed Data : Scand J Gastroenterol. 2011 Sep 22. Epub 2011 Sep 22. PMID: 21936725

Article Published Date : Sep 22, 2011

Study Type : Animal Study

Additional Links

Diseases : Animal Diseases: Scrapie, Prion Diseases, Scrapie

Problem Substances : Acid Blockers, Omeprazole (trade name Prilosec)

[+]

Histamine receptor antagonists and proton pump inhibitors cause gastric hyperplasia and cancer in rats.Jan 01, 1988

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Pubmed Data : Toxicol Pathol. 1988;16(2):288-98. PMID: 2903544

Article Published Date : Jan 01, 1988

Study Type : Animal Study

Additional Links

Diseases : Gastric Cancer

Additional Keywords : Drug: Omeprazole

Problem Substances : Histamine Receptor Antagonists, Omeprazole (trade name Prilosec), Proton-Pump Inhibitors

[+]

Long-term exposure to rats with the proton pump inhibitor omeprazole resulted in hypergastrinaemia and gastric cancer.Jan 01, 1986

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Pubmed Data : Scand J Gastroenterol Suppl. 1986;118:31-8. PMID: 3460170

Article Published Date : Jan 01, 1986

Study Type : Animal Study

Additional Links

Diseases : Gastric Cancer

Additional Keywords : Drug: Omeprazole

Problem Substances : Omeprazole (trade name Prilosec), Proton-Pump Inhibitors

Adverse Pharmacological Actions : Carcinogen

[+]

Long-term proton pump inhibitor administration caused physiological and microbiota changes in rats.Jan 20, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Rep. 2020 Jan 21 ;10(1):866. Epub 2020 Jan 21. PMID: 31964941

Article Published Date : Jan 20, 2020

Study Type : Animal Study

Additional Links

Diseases : Dysbiosis

Additional Keywords : Risk Factors

Problem Substances : Omeprazole (trade name Prilosec), Proton-Pump Inhibitors

Research Articles 11
Cumulative Knowledge Score 17
Overall Research Rating GOOD

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Focus Your Research

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Omeprazole (trade name Prilosec) is a Sub of the following Topic

View the Evidence: 11 Abstracts with Omeprazole (trade name Prilosec) Research

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Currently Available Sorting Options

Long-term use of omeprazole is suggested to induce an oxidative stress condition, which causes neurotoxicity and cognitive decline.Feb 21, 2021

Omeprazole has been linked to interstitial nephritis.May 01, 2010

Omeprazole treatment have caused considerable changes in stool culture results.Feb 28, 2017

Proton pump inhibitors reduce the bioavailability of dietary vitamin C.Sep 15, 2005

Proton-pump inhibitor therapy induces acid-related symptoms in healthy volunteers after withdrawal of therapy, indicating the drug causes rebound acid hypersecretion (RAHS).Jul 01, 2009

Severe hypomagnesaemia and subsequent seizure has been reported in long-term users of proton-pump inhibitors.Aug 01, 2008

Treatment of functional constipation by Psyllium seed in patients with gastroesophageal reflux disease leads to improvement and lessens its recurrence.Dec 31, 2017

Acid blockers increase the risk of prion infection in mice. Sep 22, 2011

Histamine receptor antagonists and proton pump inhibitors cause gastric hyperplasia and cancer in rats.Jan 01, 1988

Long-term exposure to rats with the proton pump inhibitor omeprazole resulted in hypergastrinaemia and gastric cancer.Jan 01, 1986

Long-term proton pump inhibitor administration caused physiological and microbiota changes in rats.Jan 20, 2020

Omeprazole (trade name Prilosec) Related Articles

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Omeprazole (trade name Prilosec)

View the Evidence:
11 Abstracts with Omeprazole (trade name Prilosec) Research