Indomethacin

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25 Diseases Researched for Indomethacin
NameACCKFocus
Gastric Ulcer3161Locked
Drug-Induced Toxicity: Indomethacin2141Locked
Inflammation816Locked
Cardiac Mortality 110Locked
Cardiovascular Diseases110Locked
Coronary Artery Disease110Locked
Myocardial Infarction110Locked
Oxidative Stress36Locked
Alcohol Toxicity 24Locked
Dysbiosis24Locked
Lipid Peroxidation24Locked
NSAID-induced toxicity 24Locked
Acetaminophen (Tylenol) Toxicity 12Locked
Aspirin-Induced Toxicity 12Locked
Colitis12Locked
Gastric Ulcers12Locked
Gastrointestinal Inflammation12Locked
Helicobacter Pylori Infection12Locked
Ileitis12Locked
Infertility: Female12Locked
Inflammatory Bowel Diseases12Locked
Prenatal Chemical Exposures12Locked
Anemia11Locked
Coronavirus Infection11Locked
Drug-Induced Toxicity: Gastrointestinal11Locked
1 Adverse Pharmacological Actions Researched for Indomethacin
NameACCKFocus
Cardiotoxic110Locked
Related Topics

Indomethacin is a Sub of the following Topic

View the Evidence:
53 Abstracts with Indomethacin Research

[+]

The use of rofecoxib, valdecoxib, and indomethacin increases the risk of cardiovascular disease.Nov 01, 2009

Pubmed Data : Pharmacoepidemiol Drug Saf. 2009 Nov;18(11):1053-63. PMID: 19637402
Article Published Date : Nov 01, 2009
Study Type : Human Study
Additional Links
Diseases : Cardiac Mortality , Cardiovascular Diseases, Coronary Artery Disease, Myocardial Infarction
Problem Substances : Indomethacin, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), Rofecoxib, Valdecoxib
Adverse Pharmacological Actions : Cardiotoxic
[+]

Apium extract alleviates indomethacin-induced gastric ulcers.Feb 13, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Med Ther. 2024 Feb 14 ;24(1):88. Epub 2024 Feb 14. PMID: 38355510
Article Published Date : Feb 13, 2024
Study Type : Animal Study
Additional Links
Substances : Celery
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Inflammatory Agents, Anti-Ulcer Agents, NF-kappaB Inhibitor
Additional Keywords : Drug: Indomethacin
Problem Substances : Indomethacin
[+]

Apple polyphenols suppresses indomethacin-induced gastric damage.Oct 31, 2017

Pubmed Data : J Med Food. 2017 Nov ;20(11):1113-1120. PMID: 29120271
Article Published Date : Oct 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Apple Polyphenols
Diseases : Drug-Induced Toxicity: Indomethacin
Pharmacological Actions : Antioxidants, Gastroprotective
Problem Substances : Indomethacin
[+]

Astragaloside IV ameliorates indomethacin-induced intestinal inflammation.Jun 29, 2024

Pubmed Data : Int Immunopharmacol. 2024 Jun 30 ;135:112281. Epub 2024 May 19. PMID: 38762925
Article Published Date : Jun 29, 2024
Study Type : Animal Study
Additional Links
Substances : Astragaloside
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, NF-kappaB Inhibitor
Problem Substances : Indomethacin, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

Avocado seeds extract may be a suitable natural source for the prevention and treatment of gastric ulcer.Apr 30, 2019

Pubmed Data : Food Res Int. 2019 May ;119:751-760. Epub 2018 Oct 22. PMID: 30884712
Article Published Date : Apr 30, 2019
Study Type : Animal Study
Additional Links
Substances : Avocado
Diseases : Drug-Induced Toxicity: Indomethacin, Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents, Gastroprotective
Problem Substances : Indomethacin
[+]

Benzyl isothiocyanates modulate inflammation, oxidative stress, and apoptosis in indomethacin-induced gastric injury.Jul 06, 2021

Pubmed Data : Food Funct. 2021 Jul 7 ;12(13):6001-6013. Epub 2021 May 26. PMID: 34037056
Article Published Date : Jul 06, 2021
Study Type : Animal Study
Additional Links
Substances : Benzyl isothiocyanate
Diseases : Drug-Induced Toxicity: Indomethacin, Gastric Ulcer, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Anti-Ulcer Agents, Heme oxygenase-1 up-regulation, NF-kappaB Inhibitor, Nrf2 activation
Problem Substances : Indomethacin
[+]

Caffeic acid phenethyl ester attenuates indomethacin-induced gastric ulcer.Sep 22, 2023

Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2023 Sep 23. Epub 2023 Sep 23. PMID: 37740773
Article Published Date : Sep 22, 2023
Study Type : Animal Study
Additional Links
Substances : Caffeic acid phenethyl ester
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents
Problem Substances : Indomethacin
[+]

Carnosic acid ameliorates indomethacin-induced gastric ulceration.Mar 08, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomedicines. 2023 Mar 9 ;11(3). Epub 2023 Mar 9. PMID: 36979808
Article Published Date : Mar 08, 2023
Study Type : Animal Study
Additional Links
Substances : Carnosic Acid
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Inflammatory Agents, Anti-Ulcer Agents, Antioxidants, Heme oxygenase-1 up-regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nrf2 activation
Problem Substances : Indomethacin
[+]

Chrysin possesses a potential protective effect against indomethacin-induced gastric ulcer.Jan 04, 2018

Pubmed Data : Eur J Pharmacol. 2018 Jan 5 ;818:486-498. Epub 2017 Nov 8. PMID: 29126792
Article Published Date : Jan 04, 2018
Study Type : Animal Study
Additional Links
Substances : Chrysin
Diseases : Drug-Induced Toxicity: Indomethacin, Gastric Ulcer, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Anti-Ulcer Agents, Antioxidants, Gastroprotective
Problem Substances : Indomethacin
[+]

Colon targeting of naringin for enhanced cytoprotection against indomethacin-induced colitis.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Des Devel Ther. 2020 ;14:677-696. Epub 2020 Feb 19. PMID: 32109993
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Colitis, Drug-Induced Toxicity: Indomethacin
Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Indomethacin
[+]

Commonly taken analgesics could decrease germ cell number and ovarian size in F1 offspring in rats.Jan 26, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2016 Jan 27 ;6:19789. Epub 2016 Jan 27. PMID: 26813099
Article Published Date : Jan 26, 2016
Study Type : Animal Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity , Infertility: Female, Prenatal Chemical Exposures
Additional Keywords : Acetaminophen (Tylenol) Toxicity, Infertility: Female, Prenatal Chemical Exposures, Transgenerational Epigenetic Modification
Problem Substances : Acetaminophen, Analgesic: Non-opioid, Indomethacin, Paracetamol
[+]

Depletion of gut microbiota with antibiotics led to a higher mortality in mice compared to controls.Jan 08, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Jan 9 ;7:40317. Epub 2017 Jan 9. PMID: 28067296
Article Published Date : Jan 08, 2017
Study Type : Animal Study
Additional Links
Diseases : Drug-Induced Toxicity: Indomethacin, Dysbiosis
Additional Keywords : Microbiota
Problem Substances : Indomethacin, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

Different protective capability of chlorogenic acid and quercetin against indomethacin-induced gastrointestinal ulceration.Jan 06, 2023

Pubmed Data : J Pharm Pharmacol. 2023 Jan 7. Epub 2023 Jan 7. PMID: 36617303
Article Published Date : Jan 06, 2023
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid, Quercetin
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents, Gastroprotective
Problem Substances : Indomethacin
[+]

Extracts of M. vulgare and marrubiin display antiulcer activities. Aug 31, 2011

Pubmed Data : J Pharm Pharmacol. 2011 Sep ;63(9):1230-7. Epub 2011 Jul 7. PMID: 21827496
Article Published Date : Aug 31, 2011
Study Type : Animal Study
Additional Links
Substances : Horehound
Diseases : Alcohol Toxicity , Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents, Gastroprotective
Additional Keywords : Plant Extracts
Problem Substances : Indomethacin
[+]

Galangin and kaempferol alleviate the indomethacin-caused cytotoxicity and barrier loss in rat intestinal epithelial cells.Jun 14, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : ACS Omega. 2021 Jun 15 ;6(23):15046-15056. Epub 2021 May 29. PMID: 34151085
Article Published Date : Jun 14, 2021
Study Type : Animal Study
Additional Links
Substances : Flavonoids, Kaempferol
Diseases : Drug-Induced Toxicity: Indomethacin
Pharmacological Actions : Gastroprotective
Problem Substances : Indomethacin
[+]

Gastroprotective effect of Hyssopus officinalis L. leaves.Nov 06, 2019

Pubmed Data : Drug Chem Toxicol. 2019 Nov 7:1-10. Epub 2019 Nov 7. PMID: 31694395
Article Published Date : Nov 06, 2019
Study Type : Animal Study
Additional Links
Substances : Hyssop
Diseases : Gastric Ulcer
Pharmacological Actions : Gastroprotective
Problem Substances : Indomethacin
[+]

Gastroprotective effect of oral kefir on indomethacin-induced acute gastric lesions.Sep 14, 2018

Pubmed Data : Life Sci. 2018 Sep 15 ;209:370-376. Epub 2018 Aug 16. PMID: 30120965
Article Published Date : Sep 14, 2018
Study Type : Animal Study
Additional Links
Substances : Kefir
Diseases : Drug-Induced Toxicity: Indomethacin, Gastric Ulcer, Oxidative Stress
Pharmacological Actions : Anti-Ulcer Agents, Antioxidants, Gastroprotective
Problem Substances : Indomethacin, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

Gastroprotective effects of oleuropein and thymol on indomethacin-induced gastric ulcerNov 13, 2018

Pubmed Data : Drug Chem Toxicol. 2018 Nov 14:1-13. Epub 2018 Nov 14. PMID: 30426792
Article Published Date : Nov 13, 2018
Study Type : Animal Study
Additional Links
Substances : Oleuropein, Thymol
Diseases : Drug-Induced Toxicity: Indomethacin, Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents, Gastroprotective
Problem Substances : Indomethacin
[+]

Ginsenoside Rd therapy improves histological and functional recovery in a model of inflammatory bowel disease. May 27, 2020

Pubmed Data : Phytother Res. 2020 May 28. Epub 2020 May 28. PMID: 32468636
Article Published Date : May 27, 2020
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Inflammatory Bowel Diseases
Pharmacological Actions : Gastrointestinal Agents
Problem Substances : Indomethacin
[+]

Influences of turmeric supplemented diet on the expression of defensive and destructive factors in indomethacin-induced ulcer.Jul 03, 2023

Pubmed Data : Nutr Health. 2023 Jul 4:2601060231185607. Epub 2023 Jul 4. PMID: 37403382
Article Published Date : Jul 03, 2023
Study Type : Animal Study
Additional Links
Substances : Turmeric
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents, Gastroprotective
Additional Keywords : Gene Expression Regulation
Problem Substances : Indomethacin
[+]

Investigation on the gastroprotective and antidiarrhoeal properties of Aegle marmelos unripe fruit extract.Oct 31, 2003

Pubmed Data : Hindustan Antibiot Bull. 2003 Feb-2004 Nov;45-46(1-4):41-6. PMID: 16281828
Article Published Date : Oct 31, 2003
Study Type : Animal Study
Additional Links
Substances : Bael
Diseases : Alcohol Toxicity , Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents, Antidiarrheals, Gastroprotective
Additional Keywords : Plant Extracts
Problem Substances : Indomethacin, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

Mechanisms underlying gastroprotective effect of paeonol against indomethacin-induced ulcer in rats.Apr 30, 2019

Pubmed Data : Hum Exp Toxicol. 2019 May ;38(5):510-518. Epub 2018 Dec 24. PMID: 30580614
Article Published Date : Apr 30, 2019
Study Type : Animal Study
Additional Links
Substances : Paeonol
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Anti-Ulcer Agents, Antioxidants, Interleukin-1 beta downregulation, Malondialdehyde Down-regulation, NF-kappaB Inhibitor, Superoxide Dismutase Up-regulation
Problem Substances : Indomethacin
[+]

Milk fermented with Lactobacillus fermentum ameliorates indomethacin-induced intestinal inflammation.Jul 15, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2019 Jul 16 ;11(7). Epub 2019 Jul 16. PMID: 31315186
Article Published Date : Jul 15, 2019
Study Type : Animal Study
Additional Links
Substances : Fermented Foods and Beverages, Lactobacillus fermentum, Milk: Fermented
Diseases : Gastrointestinal Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
Problem Substances : Indomethacin
[+]

O. europaea extract can be used to decrease some side effects of indomethacin on intestinal tissue.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2020 ;2020:6669813. Epub 2020 Dec 23. PMID: 33424990
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Olive
Diseases : Drug-Induced Toxicity: Indomethacin
Pharmacological Actions : Gastroprotective
Problem Substances : Indomethacin
[+]

Optimization of thymoquinone-loaded self-nanoemulsion for management of indomethacin-induced ulcer.Mar 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Dose Response. 2021 Apr-Jun;19(2):15593258211013655. Epub 2021 May 10. PMID: 33994890
Article Published Date : Mar 31, 2021
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Drug-Induced Toxicity: Indomethacin, Gastric Ulcers
Pharmacological Actions : Anti-Ulcer Agents, Antioxidants, Gastroprotective
Problem Substances : Indomethacin
[+]

Optimized ellagic acid-ca pectinate floating beads for gastroprotection against indomethacin-induced gastric injury. Jul 05, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomolecules. 2020 Jul 6 ;10(7). Epub 2020 Jul 6. PMID: 32640741
Article Published Date : Jul 05, 2020
Study Type : Animal Study
Additional Links
Substances : Ellagic Acid
Diseases : Drug-Induced Toxicity: Indomethacin, Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents, Gastroprotective
Problem Substances : Indomethacin
[+]

Perilla frutescens leaf could be a potential therapeutic agent and food supplement for NSAID-induced gastric injuries.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2019 ;2019:9514703. Epub 2019 Mar 4. PMID: 30949513
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Perilla , Rosemaric Acid
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Gastroprotective
Problem Substances : Indomethacin, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

Plantago major had considerable anti-inflammatory and hepatoprotective activities.May 31, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian J Pharmacol. 2009 Jun ;41(3):120-4. PMID: 20442819
Article Published Date : May 31, 2009
Study Type : Animal Study
Additional Links
Substances : Plantago
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective
Additional Keywords : Natural Substances Versus Drugs
Problem Substances : Indomethacin
[+]

Pre-treatment with Boswellia gum resin tablets decreased the severity of inflammation and number of bleeding spots among ulcer-induced rabbits.Mar 31, 2016

Pubmed Data : AAPS PharmSciTech. 2016 Apr ;17(2):328-38. Epub 2015 Jun 20. PMID: 26092303
Article Published Date : Mar 31, 2016
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Gastric Ulcer, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Gastroprotective
Problem Substances : Indomethacin
[+]

Processed Aloe vera gel attenuates non-steroidal anti-inflammatory drug-induced small intestinal injuryAug 31, 2019

Pubmed Data : Food Funct. 2019 Sep 1 ;10(9):6088-6097. Epub 2019 Sep 6. PMID: 31490512
Article Published Date : Aug 31, 2019
Study Type : Animal Study
Additional Links
Substances : Aloe Vera
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Inflammatory Agents, Anti-Ulcer Agents, Gastroprotective
Problem Substances : Indomethacin, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

Protective effect of astaxanthin on indomethacin-induced gastric ulcerations.Jun 27, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2024 Jun 28. Epub 2024 Jun 28. PMID: 38940848
Article Published Date : Jun 27, 2024
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents, Gastroprotective
Problem Substances : Indomethacin
[+]

Protective effect of two extracts of quince fruits on gastric ulcer induced by indomethacin.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Prev Med. 2017 ;8:58. Epub 2017 Aug 24. PMID: 28900537
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Quince
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents
Problem Substances : Indomethacin
[+]

Protective effect of valerian extract capsule (VEC) on ethanol- and indomethacin-induced gastric mucosa injury.Nov 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharm Biol. 2022 Dec ;60(1):1095-1105. PMID: 35658820
Article Published Date : Nov 30, 2022
Study Type : Animal Study
Additional Links
Substances : Valerian
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents, Gastroprotective
Additional Keywords : Drug: Indomethacin, Plant Extracts
Problem Substances : Indomethacin
[+]

Protective effects of escin against indomethacin-induced gastric ulcer.Nov 30, 2014

Pubmed Data : Toxicol Mech Methods. 2014 Dec ;24(8):560-6. PMID: 25137224
Article Published Date : Nov 30, 2014
Study Type : Animal Study
Additional Links
Substances : Horse Chestnut
Diseases : Drug-Induced Toxicity: Indomethacin, Gastric Ulcer, Lipid Peroxidation
Pharmacological Actions : Anti-Inflammatory Agents, Anti-Ulcer Agents, Antioxidants, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Indomethacin, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

Protective effects of trigonelline against indomethacin-induced gastric ulcer.Dec 31, 2015

Pubmed Data : Food Funct. 2016 Jan ;7(1):398-408. PMID: 26499137
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Fenugreek
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Inflammatory Agents, Anti-Ulcer Agents, Interferon Gamma Reducer, Interleukin-10 upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Indomethacin
[+]

Protective effects of triple fermented barley extract on indomethacin-induced gastric mucosal damage in rats.Feb 19, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2019 Feb 20 ;19(1):49. Epub 2019 Feb 20. PMID: 30786935
Article Published Date : Feb 19, 2019
Study Type : Animal Study
Additional Links
Substances : Barley
Diseases : Gastric Ulcer, Lipid Peroxidation
Pharmacological Actions : Anti-Ulcer Agents, Antioxidants, Gastroprotective, Glutathione Upregulation
Additional Keywords : Plant Extracts
Problem Substances : Indomethacin
[+]

Protective role of β-patchoulene from Pogostemon cablin against indomethacin-induced gastric ulcer.Jan 14, 2018

Pubmed Data : Phytomedicine. 2018 Jan 15 ;39:111-118. Epub 2017 Dec 25. PMID: 29433672
Article Published Date : Jan 14, 2018
Study Type : Animal Study
Additional Links
Substances : Patchouli
Diseases : Drug-Induced Toxicity: Indomethacin, Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents, Gastroprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Indomethacin, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

Pycnogenol reduced the toxic effect of indomethacin on the stomach and increased anti-inflammatory activity.Aug 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Gen Physiol Biophys. 2022 Sep ;41(5):473-481. PMID: 36222345
Article Published Date : Aug 31, 2022
Study Type : Animal Study
Additional Links
Substances : Flavonoids, Pycnogenol (Pine Bark)
Diseases : Drug-Induced Toxicity: Indomethacin
Pharmacological Actions : Anti-Inflammatory Agents, Anti-Ulcer Agents, Cyclooxygenase 1 Inhibitor, Gastrointestinal Agents, Gastroprotective, Malondialdehyde Down-regulation
Additional Keywords : Natural Substance/Drug Synergy, Plant Extracts
Problem Substances : Indomethacin
[+]

Spirulina and wheatgrass can partly protect the gastric mucosa against indomethacin-induced damage.Sep 30, 2019

Pubmed Data : Mol Biol Rep. 2019 Oct ;46(5):4843-4860. Epub 2019 Jul 11. PMID: 31297714
Article Published Date : Sep 30, 2019
Study Type : Animal Study
Additional Links
Substances : Spirulina, Wheat Grass
Diseases : Gastric Ulcer
Pharmacological Actions : Antioxidants, Gastroprotective
Additional Keywords : Natural Substances Versus Drugs
Problem Substances : Indomethacin
[+]

Sulforaphane contributes to the protection of gastrointestinal mucosa against oxidative injury induced by H. pylori or NSAIDs.Feb 05, 2017

Pubmed Data : Curr Pharm Des. 2017 Feb 6. Epub 2017 Feb 6. PMID: 28176666
Article Published Date : Feb 05, 2017
Study Type : Animal Study
Additional Links
Substances : Sulforaphane
Diseases : Aspirin-Induced Toxicity , Drug-Induced Toxicity: Indomethacin, Helicobacter Pylori Infection, NSAID-induced toxicity
Pharmacological Actions : Antioxidants
Problem Substances : Aspirin , Indomethacin, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

T. gondii and indomethacin trigger acute ileitis.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2012 ;7(7):e41594. Epub 2012 Jul 25. PMID: 22848538
Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Diseases : Dysbiosis, Ileitis, Inflammation
Problem Substances : Indomethacin
[+]

The effects of antioxidant combination on indomethacin-induced gastric mucosal injury.Mar 30, 2019

Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2019 Mar 31 ;65(3):76-83. Epub 2019 Mar 31. PMID: 30942158
Article Published Date : Mar 30, 2019
Study Type : Animal Study
Additional Links
Substances : beta-Carotene, Vitamin C, Vitamin E
Diseases : Drug-Induced Toxicity: Indomethacin
Pharmacological Actions : Antioxidants, Gastroprotective
Problem Substances : Indomethacin
[+]

The effects of dragon fruit extract on indomethacin-induced stomach ulcer.Aug 31, 2022

Pubmed Data : J Food Biochem. 2022 Sep ;46(9):e14274. Epub 2022 Jun 18. PMID: 35716002
Article Published Date : Aug 31, 2022
Study Type : Animal Study
Additional Links
Substances : Dragon Fruit
Diseases : Drug-Induced Toxicity: Indomethacin, Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents, Antioxidants
Problem Substances : Indomethacin, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

The protective effect of walnut oligopeptides against indomethacin-induced gastric ulcer.Mar 29, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2023 Mar 30 ;15(7). Epub 2023 Mar 30. PMID: 37049515
Article Published Date : Mar 29, 2023
Study Type : Animal Study
Additional Links
Substances : Walnut
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Inflammatory Agents, Anti-Ulcer Agents, Antioxidants, Gastroprotective
Problem Substances : Indomethacin
[+]

The statin atorvastatin increase indomethacin-induced gastric injury model in rats.Sep 30, 2012

Pubmed Data : Turk J Gastroenterol. 2012 Oct ;23(5):456-62. PMID: 23161290
Article Published Date : Sep 30, 2012
Study Type : Animal Study
Additional Links
Diseases : Drug-Induced Toxicity: Indomethacin, NSAID-induced toxicity
Problem Substances : Atorvastatin, Indomethacin, Statin Drugs
[+]

Therapeutic effect of bromelain and papain on intestinal injury induced by indomethacin.Dec 31, 2022

Pubmed Data : Int J Health Sci (Qassim). 2023 ;17(5):23-30. PMID: 37692988
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Bromelain, Papain
Diseases : Drug-Induced Toxicity: Indomethacin
Pharmacological Actions : Gastroprotective
Problem Substances : Indomethacin
[+]

Therapeutic effect of Ga-Al-As diode laser irradiation on experimentally induced inflammation.Dec 31, 1991

Pubmed Data : Lasers Surg Med. 1992 ;12(4):441-9. PMID: 1495372
Article Published Date : Dec 31, 1991
Study Type : Animal Study
Additional Links
Diseases : Inflammation
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Superiority of Natural Substances versus Drugs
Problem Substances : Indomethacin
[+]

Therapeutic versus preventative use of Ginkgo biloba extract against indomethacin-induced gastric ulcer.Aug 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2022 Aug 31 ;27(17). Epub 2022 Aug 31. PMID: 36080365
Article Published Date : Aug 30, 2022
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Inflammatory Agents, Anti-Ulcer Agents, Cyclooxygenase 2 Inhibitors, Gastroprotective
Problem Substances : Indomethacin
[+]

These findings confirm Carpolobia lutea’s ethnomedical use in anti-inflammatory pain and in pains from gastric ulcer-associated symptoms.Jul 31, 2011

Pubmed Data : Inflammopharmacology. 2011 Aug ;19(4):215-25. Epub 2011 Feb 24. PMID: 21347744
Article Published Date : Jul 31, 2011
Study Type : Animal Study
Additional Links
Substances : Carpolobia lutea
Diseases : Gastric Ulcer, Inflammation
Pharmacological Actions : Antinoceceptive
Additional Keywords : Gastric Ulcer, Inflammation, Plant Extracts, Superiority of Natural Substances versus Drugs
Problem Substances : Indomethacin
[+]

Indomethacin and resveratrol as potential treatment adjuncts for SARS-CoV-2/COVID-19.May 14, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Clin Pract. 2020 May 15:e13535. Epub 2020 May 15. PMID: 32412158
Article Published Date : May 14, 2020
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Coronavirus Infection
Pharmacological Actions : Anti-Inflammatory Agents, Antiviral Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Natural Substance/Drug Synergy
Problem Substances : Indomethacin
[+]

Natural polyphenols prevent indomethacin-induced and diclofenac-induced Caco-2 cell death.Jan 09, 2020

Pubmed Data : J Pharm Pharmacol. 2020 Jan 10. Epub 2020 Jan 10. PMID: 31922618
Article Published Date : Jan 09, 2020
Study Type : In Vitro Study
Additional Links
Substances : Caffeic Acid, Curcumin, EGCG (Epigallocatechin gallate), Gallic Acid, Naringenin , Piperine, Polyphenols, Quercetin, Rutin, Silymarin
Diseases : Drug-Induced Toxicity: Gastrointestinal, Drug-Induced Toxicity: Indomethacin
Pharmacological Actions : Antioxidants, Gastroprotective
Problem Substances : Diclofenac, Indomethacin, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

Non-steroidal anti-inflammatory drugs exhibit direct cytotoxicity against erthyrocytes (red blood cells) in vitro in an acidic media. Dec 01, 2002

Pubmed Data : Pharmazie. 2002 Dec;57(12):848-51. PMID: 12561250
Article Published Date : Dec 01, 2002
Study Type : In Vitro Study
Additional Links
Diseases : Anemia
Problem Substances : Aspirin , Ibuprofen, Indomethacin, Meloxicam, Naproxen, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), Paracetamol
[+]

The gastroprotective effect of pogostone from Pogostemonis Herba against indomethacin-induced gastric ulcer.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Biol Med (Maywood). 2016 Jan ;241(2):193-204. Epub 2015 Aug 19. PMID: 26290140
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Patchouli
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Apoptotic, Anti-Ulcer Agents, Gastrointestinal Agents, Gastroprotective
Problem Substances : Indomethacin

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