Glipizide

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8 Diseases Researched for Glipizide

Name	AC	CK
Diabetes Mellitus: Type 2	3	50
Coronary Artery Disease	2	40
Diabetes: Cardiovascular Illness	2	40
Mortality: All-Cause	1	20
Cancers: All	1	10
Hypoglycemia	1	10
Purpuric Dermatosis	1	3
Drug-Induced Toxicity	1	1

3 Adverse Pharmacological Actions Researched for Glipizide

Name	AC	CK
Cardiotoxic	2	40
Hypoglycemic	1	10
Phototoxicity	1	1

Research Articles 7
Cumulative Knowledge Score 11
Overall Research Rating GOOD

View the Evidence:
7 Abstracts with Glipizide Research

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There is a trend toward an increased overall mortality risk with glyburide versus glimepiride and glipizide versus glimepiride (1.39 [0.99-1.96]) in those with documented coronary artery disease.Jun 01, 2010

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Pubmed Data : Diabetes Care. 2010 Jun;33(6):1224-9. Epub 2010 Mar 9. PMID: 20215447

Article Published Date : Jun 01, 2010

Study Type : Meta Analysis

Additional Links

Diseases : Coronary Artery Disease, Diabetes: Cardiovascular Illness, Diabetes Mellitus: Type 2, Mortality: All-Cause

Problem Substances : Glipizide, Glyburide

Adverse Pharmacological Actions : Cardiotoxic

[+]

Initiating treatment of type 2 diabetes with glibenclamide or glipizide is associated with increased risk of coronary artery disease in comparison to gliclazide or glimepiride.Dec 01, 2008

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Pubmed Data : Diabetes Res Clin Pract. 2008 Dec;82(3):391-5. Epub 2008 Oct 21. PMID: 18945509

Article Published Date : Dec 01, 2008

Study Type : Meta Analysis

Additional Links

Diseases : Coronary Artery Disease, Diabetes: Cardiovascular Illness, Diabetes Mellitus: Type 2

Additional Keywords : Drug: Metformin

Problem Substances : Glibenclamide, Glipizide

Adverse Pharmacological Actions : Cardiotoxic

[+]

Several drugs are associated with weight change of varying magnitudes. Jan 31, 2015

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Pubmed Data : J Clin Endocrinol Metab. 2015 Feb ;100(2):363-70. Epub 2015 Jan 15. PMID: 25590213

Article Published Date : Jan 31, 2015

Study Type : Meta Analysis, Review

Additional Links

Diseases : Weight Gain: Drug-Induced, Weight Problems: Drug-Induced

Additional Keywords : Risk Factors, Weight Loss

Problem Substances : Glipizide, Glyburide, Mirtazapine, Olanzapine, Pioglitazone (trade Name Actos), Quetiapine, Risperidone

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Anti-infectives may increase the risk of severe hypoglycemia in glipizide or glyburide users.Aug 01, 2010

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Pubmed Data : Clin Pharmacol Ther. 2010 Aug;88(2):214-22. Epub 2010 Jun 30. PMID: 20592722

Article Published Date : Aug 01, 2010

Study Type : Human Study

Additional Links

Diseases : Hypoglycemia

Additional Keywords : Drug-to-Drug Interactions

Problem Substances : Antibiotics, Cephalexin, Cipro, Clarithromycin, Co-trimoxazole, Fluconazole, Glipizide, Glyburide, Levofloxacin

Adverse Pharmacological Actions : Hypoglycemic

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Patients with type 2 diabetes who use sulfonylureas or insulin have an increased risk for cancer-related mortality. Feb 01, 2006

Click here to read the entire abstract

Pubmed Data : Diabetes Care. 2006 Feb;29(2):254-8. PMID: 16443869

Article Published Date : Feb 01, 2006

Study Type : Human Study

Additional Links

Diseases : Cancers: All, Diabetes Mellitus: Type 2

Additional Keywords : Drug: Metformin

Problem Substances : Glipizide, Glyburide, Insulin, Metformin , Sulfonylureas

[+]

A case of Glipizide-induced pigmented purpuric dermatosis has been reported.Nov 01, 1999

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Pubmed Data : J Am Acad Dermatol. 1999 Nov;41(5 Pt 2):827-9. PMID: 10534660

Article Published Date : Nov 01, 1999

Study Type : Human: Case Report

Additional Links

Diseases : Purpuric Dermatosis

Problem Substances : Glipizide

[+]

Glipizide exhibits photoxicity in vitro.Jan 01, 2000

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Pubmed Data : In Vitr Mol Toxicol. 2000;13(1):17-24. PMID: 10900404

Article Published Date : Jan 01, 2000

Study Type : In Vitro Study

Additional Links

Diseases : Drug-Induced Toxicity

Problem Substances : Glipizide

Adverse Pharmacological Actions : Phototoxicity

Research Articles 7
Cumulative Knowledge Score 11
Overall Research Rating GOOD

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Glipizide is a Sub of the following Topic

View the Evidence: 7 Abstracts with Glipizide Research

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There is a trend toward an increased overall mortality risk with glyburide versus glimepiride and glipizide versus glimepiride (1.39 [0.99-1.96]) in those with documented coronary artery disease.Jun 01, 2010

Click here to read the entire abstract

Initiating treatment of type 2 diabetes with glibenclamide or glipizide is associated with increased risk of coronary artery disease in comparison to gliclazide or glimepiride.Dec 01, 2008

Click here to read the entire abstract

Several drugs are associated with weight change of varying magnitudes. Jan 31, 2015

Click here to read the entire abstract

Anti-infectives may increase the risk of severe hypoglycemia in glipizide or glyburide users.Aug 01, 2010

Click here to read the entire abstract

Patients with type 2 diabetes who use sulfonylureas or insulin have an increased risk for cancer-related mortality. Feb 01, 2006

Click here to read the entire abstract

A case of Glipizide-induced pigmented purpuric dermatosis has been reported.Nov 01, 1999

Click here to read the entire abstract

Glipizide exhibits photoxicity in vitro.Jan 01, 2000

Click here to read the entire abstract

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Glipizide

View the Evidence:
7 Abstracts with Glipizide Research