Bisphenol A

Name	AC	CK
Bisphenol Toxicity	1090	3753
Prenatal Chemical Exposures	161	662
Obesity	52	266
Oxidative Stress	68	222
Diabetes Mellitus: Type 2	37	215
Bisphenol-A Toxicity	52	190
Breast Cancer	83	186
Infertility: Male	50	181
Phthalate Toxicity	30	155
Inflammation	51	148
Polycystic Ovary Syndrome	17	122
Testicular Injury: Chemical/Metal Induced	49	94
Asthma	14	92
Infertility: Female	27	91
Chemically-Induced Liver Damage	32	73
Cardiovascular Diseases	14	72
Insulin Resistance	16	69
Pregnancy Complications	10	69
Neurodevelopmental Disorders	10	65
Attention Deficit Hyperactivity Disorder	6	61
Nonalcoholic fatty liver disease (NAFLD)	11	60
Fetal Origin of Adult Disease	14	54
Thyroid Diseases	7	54
Chronic Kidney Disease (CKD)	6	53
Male Reproductive Development Abnormalities	23	45
Metabolic Diseases	11	45
Autism Spectrum Disorders	8	44
Female Reproductive Development Abnormalities	16	44
Vitamin D Deficiency	5	42
Prostate Cancer	18	41
Diabetes Mellitus: Type 1	10	40
Bisphenol S Toxicity	8	39
DNA damage	22	37
Hypertension	7	36
Attention Deficit Disorder with Hyperactivity	5	34
Anxiety	9	33
Allergies	4	32
Cancers: All	20	31
All-Cause Mortality	3	30
Gestational Diabetes	3	30
Premature Birth	3	30
Atherosclerosis	6	28
High Fat Diet	9	26
Infertility	9	25
Endometriosis	4	23
Hyperuricemia	3	22
Myocardial Infarction	3	22
Paraben Toxicity	3	22
Pre-Eclampsia	3	22
Prediabetes	3	22
Infants: Low Birth Weight	3	21
Atopic Dermatitis	2	20
C-Reactive Protein	2	20
Cardiac Mortality	2	20
Dysbiosis	10	20
Dyslipidemias	2	20
Heart Failure	2	20
Sleep Disorders	2	20
Smoking	2	20
Cancer Metastasis	13	19
Depression	5	17
Bone Diseases	3	16
Hypothyroidism	5	15
Testosterone: Too Low	4	15
Thyroid Cancer	8	15
Endothelial Dysfunction	3	14
Food Allergies	3	14
Kidney Damage: Chemically-Induced	8	14
Ovarian Cancer	13	14
Puberty: Delayed	3	14
Puberty: Precocious	3	14
Fibrosis	4	13
Hepatic Steatosis	6	13
Hyperlipidemia	3	13
Liver Cancer	7	13
Autoimmune Thyroiditis	3	12
Chemical Exposure	3	12
Cognitive Decline/Dysfunction	6	12
Diabetic Nephropathy	2	12
Parkinson's Disease	2	12
Sexual Development: Dysfunctions and Abnormalities	2	12
Low Testosterone	2	11
Abortion: Spontaneous	1	10
Acne	1	10
Angina Pectoris	1	10
Breast Milk: Inadequate/Poor Quality	1	10
Breastfeeding Concerns: Chemical Exposure	1	10
Carcinoma: Non-Small-Cell Lung	1	10
Carotid Artery Narrowing	1	10
Child Abuse: Psychological Effects	1	10
Childhood Cognitive Disorders	1	10
Chronic Obstructive Pulmonary Disease	1	10
Coronary Artery Disease	1	10
Depression: Postpartum	1	10
Developmental Disorder: Children	1	10
Diabetes	1	10
Diabetes: Gestational	1	10
Endometrioma	1	10
Hemodialysis	1	10
Hyperglycemia	5	10
Infant Chemical Exposures	1	10
Iodine Deficiency	1	10
Miscarriage: Recurrent	1	10
Obesity: Abdominal	1	10
Orthodontics	1	10
Ovarian Failure	1	10
Parabens-Associated Toxicity	1	10
Social Behavior	1	10
Suicidal Behavior	1	10
Vascular Calcification	1	10
Weight Problems	1	10
and obesity	1	10
Brain Inflammation	5	9
Liver Damage	6	9
Lung Cancer	5	9
Learning disorders	5	8
Autoimmune Diseases	3	7
Colon Cancer	6	7
Lipid Peroxidation	2	7
Memory Disorders	4	7
Mineral Deficiencies: Selenium	4	7
Neuroblastoma	3	7
Breast Cancer: Triple Negative	6	6
Neurodegenerative Diseases	4	6
Brain: Oxidative Stress	3	5
Endometrial Carcinoma	1	5
Fatty Liver	1	5
Fetal Growth Retardation	2	5
Liver Fibrosis	3	5
Multiple Sclerosis	3	5
Systemic Lupus Erythematosus	1	5
Anxiety Disorders	2	4
Cancers: Drug Resistant	4	4
Colitis	2	4
Endometrial Cancer	3	4
Hypercholesterolemia	2	4
Kidney Damage	3	4
Lung Inflammation	2	4
Prenatal Nutrition	2	4
Prostatic Hyperplasia	2	4
Sperm Quality: Low	2	4
Thyroid Dysfunction	3	4
Acute Myeloid Leukemia	2	3
Alzheimer's Disease	2	3
Arrhythmias: Cardiac	2	3
Birth Defects	2	3
Bladder Cancer	3	3
Breast Cancer: Chemically-Induced	2	3
Breast Cancer: Estrogen	2	3
Breast Cancer: Prevention	2	3
Diabetic Complications	2	3
Endocannabinoid Disorders	2	3
Leiomyoma	2	3
Mitochondrial Dysfunction	2	3
Oral Cancer	2	3
Schizophrenia	2	3
Aging	1	2
Allergic Rhinitis	1	2
Autism	2	2
Bone Marrow Fibrosis	1	2
Brain: Microglial Activation	1	2
Breast Cancer: Lung Metastasis	1	2
Breast Neoplasms	1	2
Cadmium Poisoning	1	2
Cancers: Canine	1	2
Cardiac Surgery	1	2
Cardiomyopathy	1	2
Cataract	1	2
Colorectal Cancer	2	2
Dental Fluorosis	1	2
Diabetes Mellitus: Type 2: Prevention	2	2
Endometrial Neoplasms	1	2
Epididymitis	1	2
Erectile Dysfunction	1	2
Eye Damage	1	2
Fructose-Induced Toxicity	1	2
Gastric Ulcer	1	2
Gastrointestinal Inflammation	1	2
HPA Axis Dysregulation	1	2
High Fructose Diet	1	2
High Sugar Diet	1	2
Hydrogen Peroxide Induced Toxicity	1	2
Hypoglycemia	1	2
Inflammatory Bowel Diseases	1	2
Ischemia	1	2
Liver Steatosis	1	2
Lower Urinary Tract Symptoms	1	2
Lung Damage	1	2
Myocardial Ischemia	1	2
Orchitis	1	2
Osteoarthritis	2	2
Ovarian Cancer: Estrogen Induced	2	2
Parasitic Diseases	1	2
Premature Puberty	1	2
Prostatic Hyperplasia: Benign	1	2
Radiation	1	2
Radiation Induced Illness	1	2
Respiratory Diseases	2	2
Sepsis	1	2
Sperm Count: Low	1	2
Testicular Diseases	1	2
Titanium Toxicity	1	2
Zinc Deficiency	1	2
preeclampsia	1	2
Alcoholic Liver Disease	1	1
Androgen Deficiency	1	1
Benzo[a]pyrene-induced Toxicity	1	1
Breast Cancer: estrogen receptor alpha-positive	1	1
Cardiomegaly	1	1
Cervical Cancer	1	1
Chemotherapy-Induced Toxicity: Doxorubicin	1	1
Chronic Disease	1	1
Coronavirus Infection	1	1
Cryptorchidism	1	1
Detoxification: Impaired	1	1
Estrogen Deficiency	1	1
Fibroids: Uterine	1	1
Hormone Insufficency	1	1
Hyperthyroidism	1	1
Immune Dysregulation: TH1/TH2 imbalance	1	1
Laryngeal Cancer	1	1
Liver Disease	1	1
Liver Injury: Ischemia/reperfusion	1	1
Low DHEA	1	1
Lymphoma	1	1
Microplastic Toxicity	1	1
Nasopharyngeal Cancer	1	1
Pancreatic Cancer	1	1
Pesticide Toxicity	1	1
Pesticide-Induced Toxicity: Organophosphates	1	1
Pituitary Tumours	1	1
Polychlorinated biphenyl toxicity	1	1
Progesterone: Low	1	1
Psychiatric Disorders	1	1
Salivary Gland Cancer	1	1
Sjogren's Syndrome	1	1
Spermatogenic Failure	1	1
Steptococcus Mutans Infections	1	1
Uterine Cancer	1	1

Name	AC	CK
Neurotoxic	63	151
Cardiotoxic	21	61
Diabetogenic	14	59
Obesogenic	15	59
Inflammatory	13	34
Endocrine Disruptor	7	28
Anti-Fertility	4	27
Immunotoxic	10	17
Endocrine Disruptor: Testes	4	16
Carcinogenic	9	13
Endocrine Disruptor: Thyroid	4	13
Genotoxic	9	13
Endocrine Disruptor: Insulin Resistance	2	11
Gastrotoxic	6	11
Immunoreactive	6	10
Oxidant	3	9
Hepatotoxic	4	6
Apoptotic	4	4
Estrogenic	3	4
Proliferative	2	3
Atherogenic	1	2
Chemoresistance upregulation	2	2
Cytotoxic	2	2
Embryotoxic	1	2
Mutagenic	2	2
Teratogenic	1	2
Bioaccumulator	1	1
Carcinogenic (suspected)	1	1
Hypertensive	1	1
Immunosuppressive	1	1
Nephrotoxic	1	1
Sulfotransferase inhibitors	1	1

[+]

Paternal bisphenol A exposure in mice impairs glucose tolerance in female offspring.Sep 01, 2020

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Pubmed Data : Food Chem Toxicol. 2020 Sep 2:111716. Epub 2020 Sep 2. PMID: 32890688

Article Published Date : Sep 01, 2020

Study Type : Animal Study

Additional Links

Diseases : Bisphenol Toxicity, Prenatal Chemical Exposures

Problem Substances : Bisphenol A

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Sex-specific oxidative damage effects induced by BPA and its analogs on primary hippocampal neurons attenuated by EGCG.Sep 27, 2020

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Pubmed Data : Chemosphere. 2020 Sep 28 ;264(Pt 1):128450. Epub 2020 Sep 28. PMID: 33007573

Article Published Date : Sep 27, 2020

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Bisphenol Toxicity

Problem Substances : Bisphenol A

Adverse Pharmacological Actions : Neurotoxic

[+]

"Lipoic acid mitigates bisphenol A-induced testicular mitochondrial toxicity in rats."May 23, 2012

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Pubmed Data : Toxicol Ind Health. 2012 May 23. Epub 2012 May 23. PMID: 22623521

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Iran J Med Sci. 2021 May ;46(3):218-227. PMID: 34083854

Article Published Date : Apr 30, 2021

Study Type : Animal Study

Additional Links

Substances : Resveratrol

Diseases : Bisphenol Toxicity, Chemically-Induced Liver Damage

Pharmacological Actions : Hepatoprotective

Problem Substances : Bisphenol A

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Alpha-lipoic acid has protective effects against bisphenol A-induced neurobehavioral toxicity.Jun 12, 2018

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Pubmed Data : Neurochem Int. 2018 Jun 13 ;118:166-175. Epub 2018 Jun 13. PMID: 29908256

Article Published Date : Jun 12, 2018

Study Type : Animal Study

Additional Links

Substances : Alpha-Lipoic Acid

Diseases : Bisphenol Toxicity

Pharmacological Actions : Neuroprotective Agents

Problem Substances : Bisphenol A

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Ameliorative effect of structurally divergent oleanane triterpenoid, 3-epifriedelinol from Ipomoea batatas against BPA-induced gonadotoxicity.Dec 28, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Environ Toxicol Pharmacol. 2017 Jul 29 ;55:137-147. Epub 2017 Jul 29. PMID: 28846990

Article Published Date : Jul 28, 2017

Study Type : Animal Study

Additional Links

Diseases : Bisphenol Toxicity, Infertility: Male

Problem Substances : Bisphenol A

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Bisphenol A aggravates renal ischemia-reperfusion injury by disrupting mitochondrial homeostasis and N-acetylcysteine mitigates the injurious outcomes.Oct 05, 2019

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Pubmed Data : IUBMB Life. 2019 Oct 6. Epub 2019 Oct 6. PMID: 31587481

Article Published Date : Oct 05, 2019

Study Type : Animal Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Bisphenol Toxicity, Ischemia

Pharmacological Actions : Renoprotective

Additional Keywords : Increased Risk

Problem Substances : Bisphenol A

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Bisphenol A alters retinal morphology, visually guided behavior, and thyroid hormone levels in zebrafish larvae.Dec 31, 2023

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Pubmed Data : Biochim Biophys Acta. 2017 May 5. Epub 2017 May 5. PMID: 28483554

Article Published Date : May 04, 2017

Study Type : Animal Study

Additional Links

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Additional Keywords : Bisphenol A, Nonalcoholic fatty liver disease (NAFLD), Risk Factors

Problem Substances : Bisphenol A

[+]

Bisphenol A coupled with a high-fat diet promotes hepatosteatosis.Apr 21, 2022

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Pubmed Data : Toxics. 2022 Apr 22 ;10(5). Epub 2022 Apr 22. PMID: 35622622

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Pubmed Data : J Immunol Res. 2020 ;2020:7573103. Epub 2020 Sep 8. PMID: 32964057

Article Published Date : Dec 31, 2019

Study Type : Animal Study

Additional Links

Diseases : Allergic Rhinitis, Bisphenol Toxicity

Additional Keywords : Increased Risk

Problem Substances : Bisphenol A

[+]

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Res Int. 2017 ;2017:3585809. Epub 2017 Mar 14. PMID: 28393075

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Diseases : Bisphenol Toxicity

Additional Keywords : Transgenerational Epigenetic Modification

Problem Substances : Bisphenol A

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Bisphenol A exposure in utero leads to epigenetic alterations in the developmental programming of uterine estrogen response.Feb 24, 2010

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Pubmed Data : FASEB J. 2010 Feb 24. Epub 2010 Feb 24. PMID: 20181937

Article Published Date : Feb 24, 2010

Study Type : Animal Study

Additional Links

Diseases : Prenatal Chemical Exposures

Problem Substances : Bisphenol A

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Bisphenol A exposure increases epididymal susceptibility to infection in mice.Oct 18, 2020

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Pubmed Data : Ecotoxicol Environ Saf. 2020 Oct 19 ;208:111476. Epub 2020 Oct 19. PMID: 33091778

Article Published Date : Oct 18, 2020

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Pubmed Data : Environ Pollut. 2020 May 29 ;265(Pt A):114880. Epub 2020 May 29. PMID: 32540565

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Bisphenol A has neurotoxic properties, and may be associated with hyperactivity, in an animal model. Oct 29, 2011

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Pubmed Data : Toxicol Lett. 2011 Oct 30 ;206(3):300-5. Epub 2011 Aug 22. PMID: 21884766

Article Published Date : Oct 29, 2011

Study Type : Animal Study

Additional Links

Diseases : Attention Deficit Disorder with Hyperactivity

Problem Substances : Bisphenol A

Adverse Pharmacological Actions : Neurotoxic

[+]

Bisphenol A impairs cognitive function and 5-HT metabolism in adult male mice by modulating the microbiota-gut-brain axis.May 25, 2021

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Pubmed Data : Chemosphere. 2021 May 26 ;282:130952. Epub 2021 May 26. PMID: 34082316

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Pubmed Data : Toxicol Appl Pharmacol. 2018 Jul 12 ;355:247-256. Epub 2018 Jul 12. PMID: 30017639

Article Published Date : Jul 11, 2018

Study Type : Animal Study

Additional Links

Diseases : Bisphenol Toxicity, Testicular Injury: Chemical/Metal Induced

Problem Substances : Bisphenol A

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Bisphenol A induced oxidative stress, inflammatory response, apoptosis and mitochondrial dysfunction in mouse colons and livers.Aug 31, 2019

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Pubmed Data : Biomed Pharmacother. 2019 Sep ;117:109182. Epub 2019 Jul 1. PMID: 31387175

Article Published Date : Aug 31, 2019

Study Type : Animal Study

Additional Links

Diseases : Bisphenol Toxicity, Chemically-Induced Liver Damage, Inflammation, Oxidative Stress

Problem Substances : Bisphenol A

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Bisphenol A induced structural changes and affected the proliferation rate of mammary glands.Feb 14, 2016

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Pubmed Data : Int J Exp Pathol. 2016 Feb 15. Epub 2016 Feb 15. PMID: 26877094

Article Published Date : Feb 14, 2016

Study Type : Animal Study

Additional Links

Diseases : Breast Cancer

Additional Keywords : Risk Factors

Problem Substances : Bisphenol A

Adverse Pharmacological Actions : Proliferative

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Bisphenol A induces accelerated cell aging in murine endothelium.Sep 28, 2021

Pubmed Data : Gen Comp Endocrinol. 2003 Sep;133(2):189-98. PMID: 12928009

Article Published Date : Sep 01, 2003

Study Type : Animal Study

Additional Links

Diseases : Birth Defects

Problem Substances : Bisphenol A

[+]

Bisphenol A modulates autophagy and exacerbates chronic kidney damage in mice.Jul 02, 2021

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Pubmed Data : Int J Mol Sci. 2021 Jul 3 ;22(13). Epub 2021 Jul 3. PMID: 34281243

Article Published Date : Jul 02, 2021

Study Type : Animal Study

Additional Links

Diseases : Bisphenol Toxicity, Chronic Kidney Disease (CKD), Oxidative Stress

Additional Keywords : Increased Risk

Problem Substances : Bisphenol A

[+]

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Pubmed Data : Toxicology. 2019 Sep 28:152299. Epub 2019 Sep 28. PMID: 31574244

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Exp Ther Med. 2020 Jan ;19(1):33-44. Epub 2019 Nov 13. PMID: 31853270

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Pubmed Data : Mol Cell Endocrinol. 2022 Jul 15 ;552:111630. Epub 2022 May 13. PMID: 35569583

Article Published Date : Jul 14, 2022

Study Type : Animal Study

Additional Links

Diseases : Bisphenol Toxicity, Obesity

Additional Keywords : Risk Factors

Problem Substances : Bisphenol A , Bisphenol S

Adverse Pharmacological Actions : Neurotoxic

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Bisphenol S modulates concentrations of bisphenol A and oestradiol in female and male mice.May 22, 2018

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Pubmed Data : Xenobiotica. 2018 May 23:1-35. Epub 2018 May 23. PMID: 29790806

Article Published Date : May 22, 2018

Study Type : Animal Study

Additional Links

Diseases : Bisphenol Toxicity

Problem Substances : Bisphenol A , Bisphenol S

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Bisphenol S promotes fat storage in multiple generations.Nov 30, 2021

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Pubmed Data : Comp Biochem Physiol C Toxicol Pharmacol. 2021 Dec ;250:109175. Epub 2021 Aug 28. PMID: 34464736

Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Toxicol Res (Camb). 2019 Mar 1 ;8(2):262-269. Epub 2019 Jan 23. PMID: 30997025

Article Published Date : Feb 28, 2019

Study Type : Animal Study

Additional Links

Substances : Boron

Diseases : Bisphenol Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Problem Substances : Bisphenol A

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Boswellic acid protects against Bisphenol-A and gamma radiation induced hepatic steatosis and cardiac remodelling.Feb 13, 2020

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Pubmed Data : Arch Physiol Biochem. 2020 Feb 14:1-19. Epub 2020 Feb 14. PMID: 32057248

Article Published Date : Feb 13, 2020

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Pubmed Data : Environ Toxicol. 2015 Nov 5. Epub 2015 Nov 5. PMID: 26537420

Article Published Date : Nov 04, 2015

Study Type : Animal Study

Additional Links

Diseases : Bisphenol Toxicity, Cadmium Poisoning

Problem Substances : Bisphenol A , Cadmium

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Problem Substances : Bisphenol A

Adverse Pharmacological Actions : Diabetogenic

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BPA could affect the mineral element contents in plant roots.Oct 05, 2016

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Pubmed Data : Ecotoxicol Environ Saf. 2016 Oct 6 ;135:115-122. Epub 2016 Aug 6. PMID: 27723463

Article Published Date : Oct 05, 2016

Study Type : Environmental, Plant Study

Additional Links

Problem Substances : Bisphenol A

[+]

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Pubmed Data : Endocrinology. 2015 May ;156(5):1659-70. Epub 2015 Apr 1. PMID: 25830705

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Pubmed Data : Toxicol Mech Methods. 2015 Sep 16:1-7. Epub 2015 Sep 16. PMID: 26376105

Article Published Date : Sep 15, 2015

Study Type : Animal Study

Additional Links

Diseases : Hyperglycemia, Oxidative Stress

Additional Keywords : Increased Risk

Problem Substances : Bisphenol A

Adverse Pharmacological Actions : Diabetogenic

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BPA exposure perturbs the insulin signaling and glucose transport in the brain, therefore, it might be a risk factor for brain insulin resistance.Jan 31, 2015

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Pubmed Data : Gen Comp Endocrinol. 2015 Feb 1 ;212:44-50. Epub 2015 Jan 28. PMID: 25637671

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Pubmed Data : Genes (Basel). 2017 Oct 13 ;8(10). Epub 2017 Oct 13. PMID: 29027980

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Pubmed Data : Reprod Toxicol. 2018 Apr ;77:94-102. Epub 2018 Feb 21. PMID: 29476780

Article Published Date : Mar 31, 2018

Study Type : Animal Study

Additional Links

Diseases : Bisphenol Toxicity

Problem Substances : Bisphenol A

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BPA is responsible for disrupting lipid metabolic processes in the offspring through increased lipid production, abnormal transport, and disruption of lipid catabolism.Feb 21, 2023

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Pubmed Data : PLoS One. 2014 ;9(2):e89096. Epub 2014 Feb 25. PMID: 24586524

Article Published Date : Dec 31, 2013

Study Type : Animal Study

Additional Links

Diseases : Cardiovascular Diseases, Fetal Origin of Adult Disease

Additional Keywords : Gene Expression, Risk Factors

Problem Substances : Bisphenol A

Adverse Pharmacological Actions : Cardiotoxic

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Co-exposure to BPA and DEHP enhances susceptibility of mammary tumors.Sep 14, 2021

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Pubmed Data : Ecotoxicol Environ Saf. 2021 Sep 15 ;221:112453. Epub 2021 Jun 26. PMID: 34186418

Article Published Date : Sep 14, 2021

Study Type : Animal Study

Additional Links

Diseases : Bisphenol Toxicity, Breast Cancer

Additional Keywords : Increased Risk

Problem Substances : Bisphenol A , Phthalates

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Combinational exposure to Bisphenol A and a high-fat diet causes trans-generational Malfunction of the female reproductive system.Nov 12, 2021

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Pubmed Data : Mol Cell Endocrinol. 2021 Nov 13 ;541:111507. Epub 2021 Nov 13. PMID: 34785282

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Pubmed Data : Mol Neurobiol. 2015 May 12. Epub 2015 May 12. PMID: 25963729

Article Published Date : May 11, 2015

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Pubmed Data : Mol Cell Endocrinol. 2015 Sep 28. Epub 2015 Sep 28. PMID: 26427651

Article Published Date : Sep 27, 2015

Study Type : Animal Study

Additional Links

Diseases : Bisphenol-A Toxicity

Additional Keywords : DNA Methylation

Problem Substances : Bisphenol A

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Developmental BPA exposures heighten prostate cancer susceptibility in a complex dose and lobe-specific manner.Jan 10, 2017

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Pubmed Data : Environ Health Perspect. 2017 07 11 ;125(7):077007. Epub 2017 Jul 11. PMID: 28728135

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Pubmed Data : Endocrinology. 2014 Mar ;155(3):805-17. Epub 2014 Jan 1. PMID: 24424067

Article Published Date : Feb 28, 2014

Study Type : Animal Study

Additional Links

Diseases : Prostate Cancer

Additional Keywords : Risk Factors

Problem Substances : Bisphenol A

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Developmental low-dose exposure to bisphenol A induces chronic inflammation, bone marrow fibrosis and reduces bone stiffness.Jul 10, 2019

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Pubmed Data : Sci Total Environ. 2018 Dec 11 ;658:250-259. Epub 2018 Dec 11. PMID: 30577020

Article Published Date : Dec 10, 2018

Study Type : Animal Study

Additional Links

Diseases : Bisphenol Toxicity

Problem Substances : Bisphenol A

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Early life BPA exposure can contribute to breast cancer development and progression by modulating the anti-tumoral immune response.Sep 04, 2017

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Pubmed Data : Sci Rep. 2017 Sep 5 ;7(1):10573. Epub 2017 Sep 5. PMID: 28874690

Article Published Date : Sep 04, 2017

Study Type : Animal Study

Additional Links

Diseases : Bisphenol Toxicity, Breast Cancer

Additional Keywords : Risk Factors, Tumor Microenvironment

Problem Substances : Bisphenol A

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Effects of perinatal exposure to bisphenol A or S in EAE model of multiple sclerosis.Feb 07, 2023

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Pubmed Data : Cell Tissue Res. 2023 Feb 8. Epub 2023 Feb 8. PMID: 36750500

Article Published Date : Feb 07, 2023

Study Type : Animal Study

Additional Links

Diseases : Bisphenol Toxicity, Multiple Sclerosis

Additional Keywords : Increased Risk

Problem Substances : Bisphenol A , Bisphenol S

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Efficacy of epigallocatechin gallate (EGCG) and its underlying mechanism in preventing bisphenol-A-induced metabolic disorders.May 04, 2024

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Pubmed Data : J Hazard Mater. 2024 May 5 ;469:134098. Epub 2024 Mar 21. PMID: 38522198

Article Published Date : May 04, 2024

Study Type : Animal Study

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Substances : EGCG (Epigallocatechin gallate)

Diseases : Bisphenol Toxicity, Dysbiosis, Metabolic Diseases

Pharmacological Actions : Gastrointestinal Agents

Problem Substances : Bisphenol A

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Efficiency of naringin against reproductive toxicity and testicular damages induced by bisphenol A.Feb 28, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Iran J Basic Med Sci. 2019 Mar ;22(3):315-523. PMID: 31156794

Article Published Date : Feb 28, 2019

Study Type : Animal Study

Additional Links

Substances : Citrus naringin

Diseases : Bisphenol Toxicity, Testicular Injury: Chemical/Metal Induced

Pharmacological Actions : Antioxidants, Cytoprotective

Problem Substances : Bisphenol A

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Environmental endocrine disruptor Bisphenol A induces metabolic derailment and obesity.Jan 15, 2023

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Pubmed Data : Endocrinology. 2006 Aug;147(8):3681-91. Epub 2006 May 4. PMID: 16675520

Article Published Date : Aug 01, 2006

Study Type : Animal Study

Additional Links

Problem Substances : Bisphenol A

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Exposure to bisphenol A caused hepatoxicity and intestinal flora disorder.Jul 20, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2022 Jul 21 ;23(14). Epub 2022 Jul 21. PMID: 35887390

Article Published Date : Jul 20, 2022

Study Type : Animal Study

Additional Links

Diseases : Bisphenol Toxicity, Chemically-Induced Liver Damage, Oxidative Stress

Problem Substances : Bisphenol A

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Exposure to BPA accelerated diabetes development in NOD mice.Dec 31, 2014

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Pubmed Data : Toxicol Rep. 2015 ;2:99-110. Epub 2015 Feb 28. PMID: 28962342

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Pubmed Data : J Dev Orig Health Dis. 2018 Apr ;9(2):208-214. Epub 2017 Nov 6. PMID: 29103408

Article Published Date : Mar 31, 2018

Study Type : Animal Study

Additional Links

Diseases : Bisphenol Toxicity, Prenatal Chemical Exposures

Additional Keywords : Increased Risk

Problem Substances : Bisphenol A

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Exposure to environmentally relevant doses of the xenoestrogen bisphenol-A alters development of the fetal mouse mammary gland.Jan 01, 2007

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Pubmed Data : Endocrinology. 2007 Jan;148(1):116-27. Epub 2006 Oct 5. PMID: 17023525

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Pubmed Data : Toxicol Lett. 2019 Sep 12. Epub 2019 Sep 12. PMID: 31521832

Article Published Date : Sep 11, 2019

Study Type : Animal Study

Additional Links

Diseases : Cancers: All, Inflammation

Additional Keywords : Increased Risk, Synergistic Toxicity

Problem Substances : Aspartame, Bisphenol A , Glyphosate, Parabens, Sodium Benzoate

Adverse Pharmacological Actions : Genotoxic

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fetal BPA exposure triggers changes in the postnatal and adult mammary gland epigenome and alters gene expression patterns.Dec 31, 2013

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Pubmed Data : PLoS One. 2014 ;9(7):e99800. Epub 2014 Jul 2. PMID: 24988533

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Pubmed Data : MAGMA. 2018 Feb 20. Epub 2018 Feb 20. PMID: 29464462

Article Published Date : Feb 19, 2018

Study Type : Animal Study

Additional Links

Diseases : Bisphenol Toxicity

Problem Substances : Bisphenol A

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Gestational bisphenol A exposure advances puberty onset in female offspring.Dec 08, 2022

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Pubmed Data : Ecotoxicol Environ Saf. 2022 Dec 9 ;249:114387. Epub 2022 Dec 9. PMID: 36508816

Article Published Date : Dec 08, 2022

Study Type : Animal Study

Additional Links

Diseases : Bisphenol Toxicity, Prenatal Chemical Exposures, Puberty: Precocious

Problem Substances : Bisphenol A

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Article Published Date : Jun 29, 2022

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Bisphenol Toxicity, Chemically-Induced Liver Damage

Pharmacological Actions : Hepatoprotective

Additional Keywords : Gut-liver axis

Problem Substances : Bisphenol A

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Host developmental toxicity of BPA and BPA alternatives is inversely related to microbiota disruption in zebrafish.Oct 12, 2018

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Pubmed Data : Toxicol Sci. 2018 Oct 13. Epub 2018 Oct 13. PMID: 30321396

Article Published Date : Oct 12, 2018

Study Type : Animal Study

Additional Links

Diseases : Bisphenol Toxicity

Problem Substances : Bisphenol A , Bisphenol F, Bisphenol S

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Icariin rescues developmental BPA exposure induced spatial memory deficits in rats.Nov 30, 2023

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Pubmed Data : Toxicol Appl Pharmacol. 2023 Dec 1 ;482:116776. Epub 2023 Dec 1. PMID: 38043803

Article Published Date : Nov 30, 2023

Study Type : Animal Study

Additional Links

Substances : Icariin

Diseases : Bisphenol Toxicity

Pharmacological Actions : Neuroprotective Agents

Problem Substances : Bisphenol A

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Immunotoxicity of bisphenol S and F are similar to that of bisphenol A during zebrafish early development.Nov 22, 2017

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Pubmed Data : Chemosphere. 2017 Nov 23 ;194:1-8. Epub 2017 Nov 23. PMID: 29195089

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Pubmed Data : Chemosphere. 2021 Feb ;265:128997. Epub 2020 Nov 18. PMID: 33239236

Article Published Date : Jan 31, 2021

Study Type : Animal Study

Additional Links

Substances : Resveratrol

Diseases : Atherosclerosis, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Increased Risk

Problem Substances : Bisphenol A

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In BPA treated females cardiomyopathy incidence and severity was significantly increased compared to control females.May 08, 2017

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Pubmed Data : Toxicol Lett. 2017 May 9. Epub 2017 May 9. PMID: 28499613

Article Published Date : May 08, 2017

Study Type : Animal Study

Additional Links

Diseases : Bisphenol Toxicity, Cardiomyopathy

Additional Keywords : Increased Risk

Problem Substances : Bisphenol A

Adverse Pharmacological Actions : Cardiotoxic

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In utero exposure of BPA exerts diabetogenic and atherogenic effects with less parenchymal tissue in endocrine pancreas, kidney and uterus.Apr 30, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Iran J Basic Med Sci. 2019 May ;22(5):521-528. PMID: 31217932

Article Published Date : Apr 30, 2019

Study Type : Animal Study

Additional Links

Diseases : Bisphenol Toxicity, Prenatal Chemical Exposures

Problem Substances : Bisphenol A

Adverse Pharmacological Actions : Diabetogenic

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Paternal bisphenol A exposure in mice impairs glucose tolerance in female offspring.Sep 01, 2020

Sex-specific oxidative damage effects induced by BPA and its analogs on primary hippocampal neurons attenuated by EGCG.Sep 27, 2020

"Lipoic acid mitigates bisphenol A-induced testicular mitochondrial toxicity in rats."May 23, 2012

A comparative study of effects of 28-day exposure of bisphenol A and bisphenol S on body weight changes.Sep 30, 2021

A new chapter in the bisphenol A story: bisphenol S and bisphenol F are not safe alternatives to this compound.Dec 31, 2014

A quantitative study on the protective effects of resveratrol against bisphenol A-induced hepatotoxicity.Apr 30, 2021

A review of the environmental contamination of bisphenol A.Jun 30, 2015

A review on sources and health impacts of bisphenol A.Nov 18, 2019

A suggested bisphenol A metabolite (MBP) interfered with reproductive organ development in the chicken embryo.Jan 16, 2020

Abnormal lipid metabolism in the liver of developmental rats could be exacerbated by combined exposed to fructose and BPA.Oct 27, 2019

Adolescent BPA exposure below the safe daily limit leads to alterations in some behaviours and neuronal morphology that endure into adulthood.Feb 28, 2015

Adolescent exposure to bisphenol-a antagonizes androgen regulation of social behavior.Aug 01, 2024

Adulthood bisphenol A exposure induces anxiety in male mice.Jun 28, 2023

Adverse effects of bisphenol B exposure on the thyroid and nervous system in early life stages of zebrafish.Aug 15, 2021

Alleviating impact of hydroethanolic Murraya koenigii leaves extract on bisphenol A instigated testicular lethality and apoptosis.Jan 07, 2020

Aloe vera extract can overcome the damaging effects of BPA on the reproductive system of rats and protects rats' testes against BPA-induced toxicity.Jun 30, 2018

Alpha-lipoic acid has protective effects against bisphenol A-induced neurobehavioral toxicity.Jun 12, 2018

Ameliorative effect of structurally divergent oleanane triterpenoid, 3-epifriedelinol from Ipomoea batatas against BPA-induced gonadotoxicity.Dec 28, 2022

Analysis of indirect biomarkers of effect after exposure to low doses of bisphenol A in a study of successive generations of mice.Jan 25, 2022

Ancestral plastics exposure induces transgenerational disease-specific sperm epigenome-wide association biomarkers.Dec 31, 2020

Anti-anxiety and antidepressant-like effects of astragaloside IV and saponins extracted from Astragalus spinosus.Mar 04, 2021

Antioxidant coenzyme Q10 restores fertility by rescuing bisphenol A-induced oxidative DNA damage. Dec 17, 2019

Antioxidants reduce oxidative stress in BPA-exposed spermatozoa.Jul 21, 2019

Ashwagandha significantly ameliorates the level of BPA intoxicated oxidative stress thereby potentially treating cognitive dysfunction.May 06, 2019

Astaxanthin could rescue the BPA-mediated liver toxicity. Dec 11, 2023

Atmospheric levels of BPA associated with particulate matter in an urban environmentMar 31, 2019

Atrazine or bisphenol A mediated negative modulation of mismatch repair gene, mlh1 leads to defective oogenesis and reduced female fertility.Feb 28, 2019

Bile acids and tryptophan metabolism are novel pathways involved in metabolic abnormalities in BPA-exposed pregnant mice and male offspring.May 24, 2017

Bisphenol A affects cell viability involved in autophagy and apoptosis in goat testis sertoli cell.Jul 28, 2017

Bisphenol A aggravates renal ischemia-reperfusion injury by disrupting mitochondrial homeostasis and N-acetylcysteine mitigates the injurious outcomes.Oct 05, 2019

Bisphenol A alters retinal morphology, visually guided behavior, and thyroid hormone levels in zebrafish larvae.Dec 31, 2023

Bisphenol A and 17β-Estradiol promote arrhythmias in an animal model. Jan 01, 2011

Bisphenol A and bisphenol S disruptions of the mouse placenta and potential effects on the placenta-brain axis.Feb 17, 2020

Bisphenol A and bisphenol S induce endocrine and chromosomal alterations in brown trout.Dec 31, 2020

Bisphenol A and its analogues deteriorate the hormones physiological function of the male reproductive system.Nov 21, 2021

Bisphenol A blocks RNA splicing leading to abnormal testicular development in offspring male mice.May 06, 2019

Bisphenol A causes liver damage and selectively alters the neurochemical coding of intrahepatic parasympathetic nerves in juvenile porcine models.Dec 14, 2017

Bisphenol A causes testicular toxicity - Article 2. Mar 01, 2001

Bisphenol A causes testicular toxicity. Jul 01, 2003

Bisphenol A could risk factor for non-alcoholic fatty liver disease.May 04, 2017

Bisphenol A coupled with a high-fat diet promotes hepatosteatosis.Apr 21, 2022

Bisphenol A damages testicular junctional proteins transgenerationally in mice.Feb 25, 2022

Bisphenol A disruption promotes mammary tumor microenvironment.May 31, 2023

Bisphenol A enhances apoptosis, fibrosis, and biochemical fluctuations in the liver of adult male rats with possible regression.Jun 29, 2022

Bisphenol A exacerbates allergic inflammation.Dec 31, 2019

Bisphenol A exposure advances puberty onset by changing Kiss1 expression firstly in arcuate nucleus at juvenile period in female rats.Apr 13, 2022

Bisphenol A exposure alters placentation and causes preeclampsia-like features in pregnant mice.Oct 09, 2018

Bisphenol a exposure decreases learning ability through the suppression of mitochondrial oxidative phosphorylation in the hippocampus of male mice.May 19, 2022

Bisphenol A exposure decreases sperm production and male fertility through inhibition PCBP2 expression.Nov 19, 2023

Bisphenol A exposure disrupts organelle distribution and functions during mouse oocyte maturation.Dec 31, 2020

Bisphenol A exposure during early pregnancy impairs uterine spiral artery remodeling and provokes intrauterine growth restriction in mice.Jun 14, 2018

Bisphenol A exposure during pregnancy alters the mortality and levels of reproductive hormones and genes in offspring mice.Dec 31, 2016

Bisphenol A exposure in utero leads to epigenetic alterations in the developmental programming of uterine estrogen response.Feb 24, 2010

Bisphenol A exposure increases epididymal susceptibility to infection in mice.Oct 18, 2020

Bisphenol A exposure induces apoptosis and impairs early embryonic development in Xenopus laevis.Mar 09, 2021

Bisphenol A exposure induces cholesterol synthesis and hepatic steatosis.Aug 26, 2019

Bisphenol A exposure induces gut microbiota dysbiosis and consequent activation of gut-liver axis leading to hepatic steatosis.May 28, 2020

Bisphenol A exposure induces increased microglia and microglial related factors in the murine embryonic dorsal telencephalon and hypothalamus.Feb 28, 2018

Bisphenol A exposure induces neurobehavioral deficits and neurodegeneration through induction of oxidative stress and activated caspase-3 expression.Sep 30, 2021

Bisphenol A exposure induces sensory processing deficits in larval zebrafish during neurodevelopment.Apr 30, 2022

Bisphenol A exposure induces testicular oxidative damage.Nov 29, 2022

Bisphenol A exposure inhibits contrast sensitivity in cats involving increased response noise and inhibitory synaptic transmission.Mar 31, 2020

Bisphenol A exposure is involved in the development of Parkinson like disease in Drosophila melanogaster.Jan 13, 2020

Bisphenol A exposure remodels cognition of male rats attributable to excitatory alterations in the hippocampus and visual cortex.Oct 08, 2018

Bisphenol A exposure under metabolic stress induces accelerated cellular senescence in vivo in a p53 independent manner.Jun 24, 2019

Bisphenol A has deleterious effects on cardiac tissues.Nov 10, 2019

Bisphenol A has neurotoxic properties, and may be associated with hyperactivity, in an animal model. Oct 29, 2011

Bisphenol A impairs cognitive function and 5-HT metabolism in adult male mice by modulating the microbiota-gut-brain axis.May 25, 2021

Bisphenol A impairs reproductive fitness in zebrafish ovary.Nov 30, 2020

Bisphenol A impairs the memory function and glutamatergic homeostasisMay 28, 2017

Bisphenol A increases hydrogen peroxide generation by thyrocytes both in vivo and in vitro.Aug 31, 2018

Bisphenol A

View the Evidence:
1322 Abstracts with Bisphenol A Research