Dietary Modification: Low Carbohydrate/Ketogenic

Name	AC	CK
Obesity	72	601
Diabetes Mellitus: Type 2	45	421
Epilepsy	44	238
Polycystic Ovary Syndrome	21	211
Migraines	17	136
Seizures	18	112
Insulin Resistance	10	105
Alzheimer's Disease	34	96
Inflammation	21	93
Cancers: All	15	82
Lipoedema	9	76
Epilepsy: Childhood	7	70
Cardiovascular Diseases	9	66
Overweight	5	60
Multiple Sclerosis	11	58
Autism Spectrum Disorders	15	57
Sleep Disorders	6	42
Dravet syndrome	5	41
Parkinson's Disease	13	41
Glioblastoma	9	39
Breast Cancer	7	38
Nonalcoholic fatty liver disease (NAFLD)	7	38
Cognitive Decline/Dysfunction	7	35
Fatty Liver	5	33
Prediabetes	4	32
Hypertension	4	31
Bipolar Disorder	7	30
Metabolic Syndrome X	3	30
Brain Inflammation	12	28
Depression	13	27
Glioma	10	24
Hyperglycemia	3	22
Adiponectin: Elevated	1	21
Epileptic Seizures	3	21
Headache: Migraine	3	21
Lennox-Gastaut Syndrome	2	20
Testosterone: Too Low	2	20
Oxidative Stress	7	19
Diabetes Mellitus: Type 1	6	18
Anxiety	6	16
Dementia	4	13
Epilepsy: Infant	2	13
Metabolic Diseases	3	13
Neurodevelopmental Disorders	2	13
Traumatic Brain Injury	3	13
Acne	3	12
Alcohol Withdrawal	2	12
Atherosclerosis	2	12
Brain: Microglial Activation	2	12
Hidradenitis Suppurativa	3	12
Osteoarthritis: Knee	2	12
Psoriasis	3	12
Sepsis	3	12
Bariatric Surgery	2	11
Chronic Kidney Disease (CKD)	2	11
Chronic Pain	2	11
Eating Disorders	2	11
Encephalopathy	2	11
Lipopolysaccharide-Induced Toxicity	2	11
Liver Damage	2	11
Neurodegenerative Diseases	11	11
Aicardi Syndrome	1	10
Athletic Performance	1	10
Binge Eating	1	10
Brain Concussion	1	10
Chronic Obstructive Pulmonary Disease	1	10
Coronary Artery Disease	1	10
Diabetes: Glycation/A1C	1	10
Drug Addiction	1	10
Dysbiosis	1	10
Endometrial Cancer	1	10
Fibromyalgia	1	10
Gastric Cancer	1	10
Glucose Transporter 1 Deficiency Syndrome	1	10
Head and Neck Cancer	1	10
Headache: Cluster	1	10
Hepatic Steatosis	1	10
Hypogonadism	1	10
Infantile Spasms	1	10
Infertility: Female	1	10
Kidney Failure	1	10
Kidney Stones	1	10
Liver Cirrhosis	1	10
Liver: Fatty	1	10
Memory Disorders: Sleep Deprivation Induced	1	10
Mitochondrial Dysfunction	1	10
Muscle Soreness	1	10
Narcolepsy	1	10
Ovarian Cancer	1	10
Post-Traumatic Stress Disorders (PTSD)	1	10
Rett Syndrome	1	10
Schizophrenic Disorders	1	10
Sleep Apnea	1	10
Tuberous Sclerosis	1	10
Vitamin D Deficiency	1	10
Aging	6	9
Autism	4	8
Amyotrophic lateral sclerosis (ALS)	4	6
Brain Injury: Traumatic	3	6
Glioblastoma Multiforme	2	6
High Fat Diet	3	6
Neuroblastoma	4	6
Coronavirus Disease (Covid-19)	3	5
Neurologic Disorders	3	5
Allodynia	2	4
Asthma	2	4
Brain Cancer	4	4
Cancer Metastasis	2	4
Colon Cancer	2	4
Diabetes Mellitus: Type 2: Prevention	2	4
Headache	2	4
Hyperalgesia	2	4
Irritable Bowel Syndrome	2	4
Memory Disorders	2	4
Mitochondrial Diseases	2	4
Pancreatic Cancer	3	4
Schizophrenia	4	4
Amyotrophic Lateral Sclerosis	3	3
Arthritis: Juvenile Idiopathic	1	3
Aspartate-glutamate carrier (AGC1) Deficiency	1	3
Cardiomyopathy: Hypertrophic	1	3
Casein Intolerance	1	3
Congenital Disorders	1	3
Down Syndrome	1	3
Dyslipidemias	1	3
Encephalitis	1	3
Gliomas	3	3
Gluten Sensitivity	1	3
Hyperinsulinism	1	3
Spinal Cord Injuries	2	3
Thyroid Cancer	2	3
Zellweger Syndrome	1	3
Aging: Brain	1	2
All-Cause Mortality	1	2
Autoimmune Diseases	1	2
Cachexia: Cancer	1	2
Cardiomyopathy	1	2
Colorectal Cancer	1	2
Diabetic Complications	1	2
Diabetic Neuropathy	1	2
Diarrhea	1	2
Fibrosis	1	2
Heart Disease: Ischemic	1	2
Huntington Disease	1	2
Hypoglycemia	1	2
Hypoxia	1	2
Influenza	1	2
Ischemia	1	2
Kabuki Make-Up Syndrome	1	2
Kidney Damage	1	2
Kidney Fibrosis	1	2
Learning disorders	1	2
Melanoma	1	2
Multiple Sclerosis: Relapsing-Remitting	1	2
Neurological Disorders	2	2
Neuropathic Pain	1	2
Osteoporosis	1	2
Peripheral Nerve Diseases	1	2
Prenatal Chemical Exposures	1	2
Prostate Cancer	1	2
Retinal Diseases	1	2
Sciatic Nerve Crush Injury	1	2
Stroke: Ischemic	2	2
Testicular Injury: Chemical/Metal Induced	1	2
Appetite Disorders	1	1
Arthritis	1	1
Astrocytoma	1	1
Atopic Dermatitis	1	1
Central Nervous System Diseases	1	1
Cerebral Ischemia	1	1
Convulsive Seizures	1	1
Diabetic Nephropathy	1	1
Excitotoxicity	1	1
Female Reproductive Development Abnormalities	1	1
Heart Failure	1	1
Hemiplegia	1	1
Hormone Imbalances: High Cortisol	1	1
Lipid Peroxidation	1	1
Liver Cancer	1	1
Liver Disease	1	1
Liver Steatosis	1	1
Mood Disorders	1	1
Obsessive-Compulsive Disorder	1	1
Polycystic Kidney Diseases	1	1
Radiation	1	1
Sarcopenia	1	1
Seborrheic Dermatitis	1	1
Stroke	1	1

[+]

Comparing the efficacy and safety of low-carbohydrate diets with low-fat diets for type 2 diabetes mellitus patients.Dec 31, 2020

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Pubmed Data : BMJ. 2021 Jan 13 ;372:m4743. Epub 2021 Jan 13. PMID: 33441384

Article Published Date : Jan 12, 2021

Study Type : Meta Analysis, Review

Additional Links

Diseases : Diabetes Mellitus: Type 2, Insulin Resistance

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

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European guidelines for obesity management in adults with a very low-calorie ketogenic diet.Dec 31, 2020

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Pubmed Data : Obes Facts. 2021 ;14(2):222-245. Epub 2021 Apr 21. PMID: 33882506

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Pubmed Data : Epilepsia Open. 2018 Mar ;3(1):9-17. Epub 2018 Feb 19. PMID: 29588983

Article Published Date : Feb 28, 2018

Study Type : Meta Analysis, Review

Additional Links

Diseases : Epilepsy

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Pharmacological Actions : Anticonvulsants

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Ketogenic diet not only has a therapeutic effect on glycemic and lipid control among patients with T2DM but also significantly contributes to their weight loss.Nov 29, 2020

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Pubmed Data : Nutr Diabetes. 2020 Nov 30 ;10(1):38. Epub 2020 Nov 30. PMID: 33257645

Article Published Date : Nov 29, 2020

Study Type : Meta Analysis, Review

Additional Links

Diseases : Diabetes Mellitus: Type 2, Insulin Resistance

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic

Additional Keywords : Anti-Obesity Agents

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Ketogenic diet was associated with lower weight loss parameters, including weight, BMI, WC, and FM, in obese or overweight women with PCOS.Dec 31, 2023

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Pubmed Data : Front Nutr. 2022 ;9:1092031. Epub 2022 Dec 13. PMID: 36583214

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Pubmed Data : PLoS One. 2016;11(5):e0155050. Epub 2016 May 9. PMID: 27159218

Article Published Date : Dec 31, 2015

Study Type : Meta Analysis

Additional Links

Diseases : Cancers: All

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Additional Keywords : Median Survival Time, Risk Reduction

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2:1 ketogenic diet and low-glycemic-index diet for the treatment of chronic and episodic migraine.Jul 27, 2023

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Pubmed Data : J Headache Pain. 2023 Jul 28 ;24(1):95. Epub 2023 Jul 28. PMID: 37501109

Article Published Date : Jul 27, 2023

Study Type : Human Study

Additional Links

Diseases : Migraines

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Pharmacological Actions : Prophylactic Agents

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Additional Keywords : Anti-Obesity Agents

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A ketogenic diet has anticonvulsant and neuroprotective effects. Jan 01, 2010

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Pubmed Data : Przegl Lek. 2010;67(3):205-12. PMID: 20687386

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Pubmed Data : Front Endocrinol (Lausanne). 2021 ;12:779636. Epub 2021 Dec 14. PMID: 34970224

Article Published Date : Dec 31, 2020

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Effect of ketogenic diet versus regular diet on voice quality of patients with Parkinson's disease.Nov 30, 2021

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Pubmed Data : Acta Neurol Belg. 2021 Dec ;121(6):1729-1732. Epub 2020 Sep 6. PMID: 32892250

Article Published Date : Nov 30, 2021

Study Type : Human Study

Additional Links

Diseases : Parkinson's Disease

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

[+]

Effect of very low-calorie ketogenic diet in combination with omega-3 on inflammation, satiety hormones, body composition, and metabolic markers.Dec 31, 2021

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Pubmed Data : Antioxidants (Basel). 2019 Dec 13 ;8(12). Epub 2019 Dec 13. PMID: 31847149

Article Published Date : Dec 12, 2019

Study Type : Human Study

Additional Links

Diseases : Obesity

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Additional Keywords : Anti-Obesity Agents

[+]

Efficacy of modified Atkins ketogenic diet in chronic cluster headache.Dec 31, 2017

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[+]

Intermittent fasting, calorie restriction, and a ketogenic diet improve mitochondrial function by reducing lipopolysaccharide signaling in monocytes during obesity.Jul 31, 2024

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Pubmed Data : Zhongguo Dang Dai Er Ke Za Zhi. 2017 Oct ;19(10):1038-1043. PMID: 29046197

Article Published Date : Sep 30, 2017

Study Type : Human Study

Additional Links

Diseases : Neurodevelopmental Disorders

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Pharmacological Actions : Neuroprotective Agents

[+]

ketogenic diet demonstrated beneficial effects on cognitive performance, mood, and sleepiness during 36 h of extended wakefulness.Jul 31, 2023

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Pubmed Data : Neurol Int. 2024 Oct 25 ;16(6):1203-1213. Epub 2024 Oct 25. PMID: 39585050

Article Published Date : Oct 24, 2024

Study Type : Human Study

Additional Links

Diseases : Migraines, Sleep Disorders

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

[+]

Ketogenic diet in adolescents and adults with epilepsy.May 31, 2014

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Pubmed Data : Seizure. 2014 Jun ;23(6):439-42. Epub 2014 Mar 12. PMID: 24675110

Article Published Date : May 31, 2014

Study Type : Human Study

Additional Links

Diseases : Seizures

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Pharmacological Actions : Anticonvulsants

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Pubmed Data : Sci Adv. 2021 Apr ;7(15). Epub 2021 Apr 9. PMID: 33837086

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Pubmed Data : Metab Brain Dis. 2017 Dec ;32(6):1935-1941. Epub 2017 Aug 14. PMID: 28808808

Article Published Date : Nov 30, 2017

Study Type : Human Study

Additional Links

Diseases : Autism Spectrum Disorders

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Pharmacological Actions : Neuroprotective Agents

[+]

Ketogenic diet-induced weight loss is associated with an increase in vitamin D levels in obese adults.Jul 08, 2019

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Pubmed Data : J Transl Int Med. 2020 Mar ;8(1):26-31. Epub 2020 May 9. PMID: 32435609

Article Published Date : Feb 29, 2020

Study Type : Human Study

Additional Links

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Pharmacological Actions : Antihypertensive Agents, Hepatoprotective, Hypolipidemic

[+]

Ketonuria and seizure control in the medium chain triglyceride and classic ketogenic diets.Apr 30, 2022

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Pubmed Data : Can J Neurol Sci. 2022 May ;49(3):433-436. Epub 2021 Jun 2. PMID: 34075859

Article Published Date : Apr 30, 2022

Study Type : Human Study

Additional Links

Diseases : Seizures

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Pharmacological Actions : Anticonvulsants

[+]

Long-term effects of a novel continuous remote care intervention including nutritional ketosis for the management of type 2 diabetes.Dec 31, 2018

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Pubmed Data : Front Endocrinol (Lausanne). 2019 ;10:348. Epub 2019 Jun 5. PMID: 31231311

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Pubmed Data : BMJ Open. 2020 Jan 21 ;10(1):e033397. Epub 2020 Jan 21. PMID: 31969366

Article Published Date : Jan 20, 2020

Study Type : Human Study

Additional Links

Diseases : Prediabetes

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Additional Keywords : Anti-Obesity Agents

[+]

Modified ketogenic diet is associated with improved cerebrospinal fluid biomarker profile, cerebral perfusion, and cerebral ketone body uptake.Jan 31, 2020

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Pubmed Data : Neurobiol Aging. 2020 Feb ;86:54-63. Epub 2019 Sep 26. PMID: 31757576

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Pubmed Data : Int J Environ Res Public Health. 2019 Jul 26 ;16(15). Epub 2019 Jul 26. PMID: 31357547

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Pubmed Data : Epilepsy Res. 2020 Apr 29 ;164:106348. Epub 2020 Apr 29. PMID: 32413817

Article Published Date : Apr 28, 2020

Study Type : Human Study

Additional Links

Diseases : Epilepsy

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Pharmacological Actions : Anticonvulsants

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The ketogenic diet could be implemented in medium resources countries and should be included in the management of children with intractable epilepsy.Dec 31, 2018

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Pubmed Data : Epilepsy Behav Case Rep. 2019 ;11:35-38. Epub 2018 Nov 23. PMID: 30619711

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This result suggests that ketosis caused by consuming a low-carbohydrate diet suppresses delayed-onset muscle soreness.Jan 08, 2025

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Pubmed Data : J Sports Med Phys Fitness. 2025 Jan 9. Epub 2025 Jan 9. PMID: 39787008

Article Published Date : Jan 08, 2025

Study Type : Human Study

Additional Links

Diseases : Muscle Soreness

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

[+]

This succinct analysis offers evidence of the enormous potential of a KD to treat drug addiction through the inhibition of microglial activation.Dec 31, 2024

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Pubmed Data : Diabetes Care. 2004 Feb ;27(2):348-53. PMID: 14747212

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Pubmed Data : J Clin Endocrinol Metab. 2020 09 1 ;105(9). PMID: 32484877

Article Published Date : Dec 31, 2019

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Pubmed Data : Endocrinol Diabetes Metab Case Rep. 2018 ;2018. Epub 2018 Mar 21. PMID: 29576869

Article Published Date : Dec 31, 2017

Study Type : Human: Case Report

Additional Links

Diseases : Diabetes Mellitus: Type 1

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Pharmacological Actions : Hypoglycemic Agents

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Management of glioblastoma multiforme in a patient treated with ketogenic metabolic therapy and modified standard of care: a 24-month follow-up.Dec 31, 2017

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Pubmed Data : Endocrinol Diabetes Metab Case Rep. 2022 Sep 1 ;2022. Epub 2022 Sep 1. PMID: 36094136

Article Published Date : Aug 31, 2022

Study Type : Human: Case Report

Additional Links

Diseases : Diabetes Mellitus: Type 2, Dyslipidemias, Obesity

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Additional Keywords : Anti-Obesity Agents, Disease Remission

[+]

The ketogenic diet compensates for AGC1 deficiency and improves myelination.Sep 23, 2015

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Pubmed Data : Epilepsia. 2015 Sep 24. Epub 2015 Sep 24. PMID: 26401995

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Pubmed Data : Neurosci Lett. 2022 Jan 3 ;770:136443. Epub 2022 Jan 3. PMID: 34990761

Article Published Date : Jan 02, 2022

Study Type : Animal Study

Additional Links

Diseases : Anxiety, Depression

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic, Exercise

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents

[+]

A diet mimicking fasting promotes regeneration and reduces autoimmunity and multiple sclerosis symptoms.Jun 06, 2016

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Pubmed Data : Cell Rep. 2016 Jun 7 ;15(10):2136-46. Epub 2016 May 26. PMID: 27239035

Article Published Date : Jun 06, 2016

Study Type : Animal Study

Additional Links

Diseases : Autoimmune Diseases, Multiple Sclerosis: Relapsing-Remitting

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic, Fasting/Caloric Restriction

Additional Keywords : Dietary Modification

[+]

A ketogenic diet alleviates the apoptosis of granulosa cells.Nov 26, 2024

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Pubmed Data : Cell Commun Signal. 2024 Nov 27 ;22(1):568. Epub 2024 Nov 27. PMID: 39604996

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Pubmed Data : Nutrition. 2019 Nov 27 ;72:110659. Epub 2019 Nov 27. PMID: 31986320

Article Published Date : Nov 26, 2019

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Pubmed Data : Theranostics. 2021 ;11(1):346-360. Epub 2021 Jan 1. PMID: 33391479

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Diseases : Brain Injury: Traumatic

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Pharmacological Actions : Neuroprotective Agents

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A novel combination of ketogenic diet, ketone supplementation and hyperbaric oxygen therapy could be used to manage metastatic cancers.Dec 31, 2014

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Pubmed Data : PLoS One. 2015 ;10(6):e0127407. Epub 2015 Jun 10. PMID: 26061868

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Pubmed Data : Asian Pac J Cancer Prev. 2015 ;16(5):2061-8. PMID: 25773851

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Substances : Omega-3 Fatty Acids

Diseases : Colon Cancer

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Pharmacological Actions : Antiproliferative

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Cannabidiol-decorated berberine-loaded microemulsions improve IBS-D therapy.Dec 31, 2022

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Pubmed Data : Int J Nanomedicine. 2023 ;18:2839-2853. Epub 2023 May 30. PMID: 37273286

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Pubmed Data : Biol Reprod. 2023 Apr 11 ;108(4):597-610. PMID: 36688496

Article Published Date : Apr 10, 2023

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Pubmed Data : Food Chem (Oxf). 2021 Dec 30 ;3:100029. Epub 2021 Jun 10. PMID: 35415644

Article Published Date : Dec 29, 2021

Study Type : Animal Study

Additional Links

Substances : Ketone Bodies

Diseases : Hyperglycemia, Obesity

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Pharmacological Actions : Hypoglycemic Agents

Additional Keywords : Anti-Obesity Agents

[+]

Inhibition of neuroblastoma tumor growth by ketogenic diet and/or calorie restriction in a CD1-Nu mouse model.Dec 31, 2014

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Pubmed Data : Epilepsia. 2015 Jul ;56(7):e95-8. Epub 2015 May 23. PMID: 26011473

Article Published Date : Jun 30, 2015

Study Type : Animal Study

Additional Links

Diseases : Inflammation

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Ketogenic diet has a therapeutic effect on chronic pain induced by inflammation and nerve injury.Dec 31, 2023

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Pubmed Data : Biomed Pharmacother. 2020 May 17 ;127:110227. Epub 2020 May 17. PMID: 32434144

Article Published Date : May 16, 2020

Study Type : Animal Study

Additional Links

Diseases : Testicular Injury: Chemical/Metal Induced

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Superoxide Dismutase Up-regulation

Problem Substances : Monosodium Glutamate (MSG)

[+]

Ketogenic diet induces an inflammatory reactive astrocytes phenotype reducing glioma growth.Feb 07, 2025

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Pubmed Data : J Nutr Biochem. 2022 Sep 29:109161. Epub 2022 Sep 29. PMID: 36184012

Article Published Date : Sep 28, 2022

Study Type : Animal Study

Additional Links

Diseases : Cardiomyopathy, Diabetic Complications

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation

[+]

Ketogenic diet modulates neuroinflammation.Apr 29, 2022

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Pubmed Data : Cell Mol Neurobiol. 2022 Apr 30. Epub 2022 Apr 30. PMID: 35499776

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Pubmed Data : Life Sci. 2023 Jan 15 ;313:121285. Epub 2022 Dec 13. PMID: 36526050

Article Published Date : Jan 14, 2023

Study Type : Animal Study

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Diseases : Polycystic Ovary Syndrome

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Pharmacological Actions : Anti-Apoptotic, Transforming growth factor beta (TGF-β) upregulation

[+]

Ketogenic diet suppresses colorectal cancer through the gut microbiome long chain fatty acid stearate.Feb 19, 2025

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Pubmed Data : Nat Commun. 2025 Feb 20 ;16(1):1792. Epub 2025 Feb 20. PMID: 39979287

Article Published Date : Feb 19, 2025

Study Type : Animal Study

Additional Links

Diseases : Colorectal Cancer

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Pharmacological Actions : Antiproliferative , Apoptotic, Gastrointestinal Agents, Immunomodulatory: Th17 downregulation

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Ketogenic diet therapy might be uniquely suited to reset the epileptogenic clock and to provide long-lasting relief from seizures even after discontinuation of the diet.Aug 05, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Neuropharmacology. 2015 Aug 6 ;99:500-509. Epub 2015 Aug 6. PMID: 26256422

Article Published Date : Aug 05, 2015

Study Type : Animal Study

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Diseases : Epilepsy

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Pharmacological Actions : Anticonvulsants

Additional Keywords : DNA Methylation, Epigenetic Modification

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Ketogenic diet treatment strongly attenuated the spontaneous recurrent seizures, ameliorated learning and memory impairments.Dec 31, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Neuropsychiatr Dis Treat. 2022 ;18:2181-2198. Epub 2022 Sep 25. PMID: 36187562

Article Published Date : Dec 31, 2021

Study Type : Animal Study

Additional Links

Diseases : Epilepsy, Memory Disorders

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Pharmacological Actions : Neuroprotective Agents

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Ketogenic diets alter the gut microbiome resulting in decreased intestinal Th17 cells. May 13, 2020

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Pubmed Data : Cell. 2020 May 14. Epub 2020 May 14. PMID: 32437658

Article Published Date : May 13, 2020

Study Type : Animal Study

Additional Links

Diseases : High Fat Diet

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Immunomodulatory: Th17 downregulation

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View the Evidence: 477 Abstracts with Dietary Modification: Low Carbohydrate/Ketogenic Research

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Comparing the efficacy and safety of low-carbohydrate diets with low-fat diets for type 2 diabetes mellitus patients.Dec 31, 2020

Comparison of the effectiveness of low carbohydrate versus low fat diets, in type 2 diabetes.Oct 18, 2022

Effect of ketogenic diets on body composition and metabolic parameters of cancer patients.Oct 07, 2022

Efficacy and safety of low and very low carbohydrate diets for type 2 diabetes remission.Jan 12, 2021

European guidelines for obesity management in adults with a very low-calorie ketogenic diet.Dec 31, 2020

Impact of ketogenic diet on weight, metabolic, and endocrine parameters in women with polycystic ovary syndrome.Feb 19, 2025

Impact of very low carbohydrate ketogenic diets on cardiovascular risk factors among patients with type 2 diabetes.Jul 18, 2024

Ketogenic diet for treatment of intractable epilepsy in adults.Feb 28, 2018

Ketogenic diet not only has a therapeutic effect on glycemic and lipid control among patients with T2DM but also significantly contributes to their weight loss.Nov 29, 2020

Ketogenic diet was associated with lower weight loss parameters, including weight, BMI, WC, and FM, in obese or overweight women with PCOS.Dec 31, 2023

Ketosis and migraine: a systematic review of the literature and meta-analysis.Dec 31, 2022

The effect of ketogenic diet on adipokines levels.Nov 30, 2024

The effects of ketogenic diet on metabolic and hormonal parameters in patients with polycystic ovary syndrome.Nov 30, 2024

The efficacy of ketogenic diets as a potential nutritional intervention for lipedemaSep 26, 2024

The results show that the KD is more effective in reducing glycated haemoglobin and body weight (BW) than a low-carbohydrate diet.Apr 30, 2022

This review indicates that KDT is safe and tolerable and that it can be an effective treatment option for infants with drug-resistant epilepsy.May 31, 2020

Effects of combined exercise and low carbohydrate ketogenic diet interventions on waist circumference and triglycerides.Jan 18, 2021

Effects of low-carbohydrate diets versus low-fat diets on metabolic risk factors in overweight and obese adults.Dec 31, 2021

Effects of the ketogenic diet on glycemic control in diabetic patients.Oct 04, 2020

Efficacy of and patient compliance with a ketogenic diet in adults with intractable epilepsy: a meta-analysis.Dec 31, 2014

Impact of a ketogenic diet on metabolic parameters in patients with obesity or overweight and with or without type 2 diabetes.Jul 05, 2020

Ketogenic diet for epilepsy: an overview of systematic review and meta-analysis.Jan 12, 2022

Ketogenic diet for the treatment of pediatric epilepsy.May 31, 2020

Low carbohydrate ketogenic diets reduce cardiovascular risk factor levels in obese or overweight patients with T2DM.Dec 31, 2021

Low-carbohydrate diets may enhance glycemic control and lipid profiles in overweight or obese T2DM patients.Dec 31, 2023

Systematic review and meta-analysis of dietary carbohydrate restriction in patients with type 2 diabetes.Dec 31, 2016

The effect of ketogenic diet on body composition and anthropometric measures.Jan 13, 2021

The ketone body, beta-hydroxybutyrate, associated with the low-carb diet and fasting may be responsible for the initial euphoria experienced by those undergoing these dietary modifications.Jan 01, 2007

The results suggested a beneficial effect of LCD intervention on glucose control in patients with type 2 diabetes.Aug 31, 2017

There was an overall tumor growth delaying effect of unrestricted ketogenic diets in mice.Dec 31, 2015

2:1 ketogenic diet and low-glycemic-index diet for the treatment of chronic and episodic migraine.Jul 27, 2023

A 1-month ketogenic diet in patients with migraine gives a clinical beneficial effect associated with increased latency of somatosensory thalamo-cortical activity.Dec 31, 2023

A 3-month ketogenic diet resulted in a reduction of painful symptoms of drug refractory chronic migraine.Jan 31, 2021

A clinically important trend toward lower migraine duration on ketogenic diet therapy was noted.Aug 25, 2021

A cross-sectional comparison of brain glucose and ketone metabolism in cognitively healthy older adults, mild cognitive impairment and early Alzheimer's disease.Jun 30, 2018

A ketogenic diet consumed during radiotherapy improves several aspects of quality of life and metabolic health in women with breast cancer.Jan 26, 2021

A ketogenic diet could help reduce the frequency of migraine attacks. Dec 31, 2015

A ketogenic diet followed by gradual carbohydrate reintroduction restores menstrual cycles in women with polycystic ovary syndrome.Dec 07, 2024

A ketogenic diet has anticonvulsant and neuroprotective effects. Jan 01, 2010

A ketogenic diet intervention is beneficial for overweight/obese women with PCOS with different serum uric acid concentrations.Jul 31, 2022

A ketogenic diet is an effective therapeutic modality for epilepsy associated with tuberous sclerosis in children. Oct 01, 2005

A Ketogenic diet is effective in refractory epilepsy of childhood.Dec 13, 1901

A ketogenic diet was associated with a greater improvement in some risk factors for coronary heart disease and MASLD.Dec 31, 2024

A ketogenic drink improves brain energy and some measures of cognition in mild cognitive impairment.Apr 30, 2019

A ketogenic supplement improves white matter energy supply and processing speed in mild cognitive impairment.Dec 31, 2020

A LCHF-diet is associated with reduction in perceived pain and improvement in QoL, in patients with lipedema.Jul 31, 2022

A low carbohydrate formula was associated with reduced insulin use and glycaemic variability in enterally-fed critically ill patients with hyperglycaemia.May 31, 2019

A low-carb diet appears to be among the most effective approaches for weight loss and body fat reduction.Nov 30, 2024

A low-carbohydrate diet is effective in lowering the HbA1c and triglyceride levels in patients with type 2 diabetes who are unable to adhere to a calorie-restricted diet.Dec 31, 2013

A low-carbohydrate diet realizes medication withdrawal: A possible opportunity for effective glycemic control .Dec 31, 2020

A low-carbohydrate, ketogenic diet improves fatty liver disease. Feb 01, 2007

A low-carbohydrate, ketogenic reduces narcolepsy symptoms.Jun 22, 2004

A multiphase very-low calorie ketogenic diet improves serum redox balance by reducing oxidative status in obese patients.Sep 30, 2024

A randomized controlled trial of pharmacist-led therapeutic carbohydrate and energy restriction in type 2 diabetes.Sep 09, 2021

A randomized trial of a moderate-carbohydrate versus very low-carbohydrate diet in overweight adults with type 2 diabetes mellitus or prediabetes.Dec 20, 2017

Addressing pain using a mediterranean ketogenic nutrition program in older adults with mild cognitive impairment.Dec 31, 2023

Alternate day fasting combined with a low-carbohydrate diet for weight loss, weight maintenance, and metabolic disease risk reduction.Nov 30, 2019

Association between low carbohydrate diet (LCD) and sleep quality by mediating role of inflammatory factors in women with overweight and obesity.Oct 31, 2021

Beneficial effects of ketogenic diet in women with polycystic ovary syndrome and liver dysfunction who are obese.Feb 28, 2021

Beyond seizure control, patients experienced a marked improvement in behavior and awareness. Dec 01, 2019

Both a modified Atkins diet and the classic ketogenic diet could be used in the treatment of intractable epilepsy in children.Dec 09, 2015

Calorically restricted diets could be effective in reducing the anxiety and in improving motor behavior in girls with Rett Syndrome.Jun 01, 2009

Changes in cerebral metabolism during ketogenic diet in patients with primary brain tumorsJan 09, 2017

Comparison of a very low-calorie-ketogenic diet with a standard low-calorie diet in the treatment of obesity.Nov 30, 2014

Consuming a modified Mediterranean ketogenic diet reverses the peripheral lipid signature of Alzheimer's disease in humans.Jan 08, 2025

Dietary carbohydrate restriction improves metabolic syndrome independent of weight loss.Jun 19, 2019

Effect of a 90 g/day low-carbohydrate diet on glycaemic control, small, dense low-density lipoprotein and carotid intima-media thickness in type 2 diabetic patients.Dec 31, 2019

Effect of a ketogenic diet on hepatic steatosis and hepatic mitochondrial metabolism in nonalcoholic fatty liver disease.Mar 30, 2020

Effect of a low-carbohydrate diet on pain and quality of life in female patients with lipedema.May 31, 2024

Effect of high-dose intravenous ascorbic acid on cancer patients following ketogenic diet.Sep 30, 2021

Effect of ketogenic diet versus regular diet on voice quality of patients with Parkinson's disease.Nov 30, 2021

Effect of very low-calorie ketogenic diet in combination with omega-3 on inflammation, satiety hormones, body composition, and metabolic markers.Dec 31, 2021

Dietary Modification: Low Carbohydrate/Ketogenic

View the Evidence:
477 Abstracts with Dietary Modification: Low Carbohydrate/Ketogenic Research