bone loss https://greenmedinfo.com/category/keywords/bone-loss en Co-administrated puerarin and zinc can partially reverse OVX-induced bone loss. https://greenmedinfo.com/article/co-administrated-puerarin-and-zinc-can-partially-reverse-ovx-induced-bone-loss n/a PMID:  Life Sci. 2016 Dec 1 ;166:20-26. Epub 2016 Sep 30. PMID: 27697446 Abstract Title:  Coadministration of puerarin (low dose) and zinc attenuates bone loss and suppresses bone marrow adiposity in ovariectomized rats. Abstract:  AIMS: Puerarin is a phytoestrogen that shows osteogenic effects. Meanwhile, zinc stimulates bone formation and inhibits bone resorption. The study aims to investigate the effects of coadministration of puerarin (low dose) and zinc on bone formation in ovariectomized rats. MATERIALS AND METHODS: Co-administration or use alone of puerarin (low dose) and/or zinc were gavaged in OVX rats. The estrogen-like effects were detected by the uterus weight, the histologic observation and the IGF-1 protein expression. The osteogenic effects were determined by bone histomorphometric and mechanical parameters, osteogenic and adipogenic blood markers, and so on. KEY FINDINGS: The results showed that oral administration of puerarin (low dose) plus zinc didn&#039;t significantly increase uterus weight. The glandular epithelial of endometrium had no proliferation and no protein expression of IGF-1. Moreover, co-administration attenuated bone loss and biomechanical decrease more than single use of puerarin or zinc (p&lt;0.05). Next, combined administration of puerarin and zinc promoted the serological level of osteocalcin, bone marrow stromal cell (BMSC) proliferation, and the expression of alkaline phosphatase (ALP), and suppressed the serological level of adiponectin and adiposity in bone marrow (BM). SIGNIFICANCE: In conclusion, co-administrated puerarin (low dose) and zinc can partially reverse OVX-induced bone loss and suppress the adiposity of BM in rats, which shed light on the potential use of puerarin and zinc in the treatment of osteoporosis. https://greenmedinfo.com/article/co-administrated-puerarin-and-zinc-can-partially-reverse-ovx-induced-bone-loss#comments Osteoporosis Puerarin Zinc Osteogenic Osteoprotective bone loss Osteoporosis Ovariectomy-Induced Changes Puerarin zinc Animal Study Fri, 02 Dec 2016 21:54:42 +0000 greenmedinfo 139815 at https://greenmedinfo.com This Humble Food Extract Puts Bone Drugs to Shame https://greenmedinfo.com/blog/humble-food-extract-puts-bone-drugs-shame <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2019<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><img alt="This Humble Food Extract Puts Bone Drugs To Shame" src="//cdn.greenmedinfo.com/sites/default/files/miso_soup.jpg" /></p> <p><span style="font-size:18px;"><em><strong>An ancient fermented food puts pharmaceutical drugs for bone loss to shame...</strong></em></span></p> <p>According to research published in the <strong><a href="/article/genistein-superior-bone-drugs-alendronate-raloxifene-and-estradiol-osteoporotic-ovariectomiz" rel="dofollow" target="_blank">British Journal of Pharmacology</a></strong> in 2008, alendronate (Fosamax), raloxifene (Evista) and estradiol (estrogen, E2) are inferior to the phytoestrogen genistein commonly found in fermented soy*, red clover, kudzu, fava beans and coffee, in preserving bone mineral density (quantity) and strength (quality) in an animal model of menopausal osteoporosis.</p><p><a href="https://greenmedinfo.com/blog/humble-food-extract-puts-bone-drugs-shame" target="_blank">read more</a></p> https://greenmedinfo.com/blog/humble-food-extract-puts-bone-drugs-shame#comments Bone Fractures Genistein Miso Osteopenia Osteoporosis Soy Soy: Fermented Bisphosphonates Raloxifine bone loss healing foods natural health Mon, 23 Jan 2012 19:09:43 +0000 Sayer Ji 64930 at https://greenmedinfo.com Why Fermented Soy May Be the Answer to Osteoporosis https://greenmedinfo.com/blog/why-fermented-soy-may-be-answer-osteoporosis <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2023<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><img alt="" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/Sayer Ji/images/213689855_m_normal_none.jpg" style="width: 600px; height: 336px;" /></p> <p><span style="font-size:18px;"><em><strong>If you are one of the estimated 40 million US-women who are aged 51 and older--past the average age of natural menopause--you may be considering hormone replacement therapy, or HRT, to maintain youthful vigor, as well as ward-off the hazards of brittle bones and heart disease. Did you know that a nutrient in fermented soy foods has been clinically-proven to put bone drugs to shame, with no negative side effects?</strong></em></span></p><p><a href="https://greenmedinfo.com/blog/why-fermented-soy-may-be-answer-osteoporosis" target="_blank">read more</a></p> https://greenmedinfo.com/blog/why-fermented-soy-may-be-answer-osteoporosis#comments Atherosclerosis Bone Diseases Chickpea Coffee Coronary Artery Disease Genistein Osteopenia Osteoporosis Pulmonary Embolism Soy Soy: Fermented Venous Thrombosis Alendronate (trade name Fosamax) Chemical and Drug Toxicity Ethinyl Estradiol Osteoporosis/Osteopenia Raloxifene big pharma bone loss natural health Wed, 22 Nov 2023 20:43:00 +0000 GMI Research Group 161589 at https://greenmedinfo.com