Detoxification https://greenmedinfo.com/category/keywords/detoxification en 4 Reasons to Break a Sweat https://greenmedinfo.com/blog/4-reasons-break-sweat <p class="rtecenter"><img alt="4 Reasons to Break a Sweat" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/lrossi/images/sweat_benefits_greenmedinfo.jpg" style="width: 600px; height: 398px;" title="4 Reasons to Break a Sweat" /></p> <p><em><span style="font-size:18px;"><strong>Your body has a natural, powerful, built-in system for detoxification that doesn't require trendy juice cleanses or expensive protocols. All you have to do is sweat!</strong></span></em></p> <p>Doctors, health experts, and fitness gurus tell us that we should break a sweat every day - and for good reason. While sweating has a host of benefits simply because it's a result of health-boosting exercise, the act of sweating itself heals the body as well. Whether you're sitting in a sauna, walking on a warm day, or working out, sweating is a necessary bodily function with powerful healing effects.</p><p><a href="https://greenmedinfo.com/blog/4-reasons-break-sweat" target="_blank">read more</a></p> https://greenmedinfo.com/blog/4-reasons-break-sweat#comments Heavy Metal Toxicity Aluminum BPA Exercise Sauna Therapy Sweating 4 Reasons to Break a Sweat BPA Detoxification exercise Heavy metals pollutants sauna sweat Mon, 07 Feb 2022 16:28:33 +0000 deannaminich 139009 at https://greenmedinfo.com Administration of 240 mg of anthocyanins a day for 30 days caused a substantial increase of glutathione peroxidase and catalase activities. While decreasing the lead, aluminum and cooper concentrations. https://greenmedinfo.com/article/administration-240-mg-anthocyanins-day-30-days-caused-substantial-increase-glu PMID:  Pol Merkur Lekarski. 2005 Nov ;19(113):651-3. PMID: 16498804 Abstract Title:  [The influence of anthocyanins from Aronia melanocarpa on selected parameters of oxidative stress and microelements contents in men with hypercholesterolemia]. Abstract:  THE AIM OF THE STUDY: Our investigations was to estimate the influence of Aronia anthocyanins (Aronox by Agropharm) on selected parameters of oxidative and antioxidative balance as well as on the concentration of selected metals in red blood cells in men with hipercholesterolaemia.MATERIAL AND METHODS: 16 men aged 27 +/- 6.4 years old with blood cholesterol concentration on the level of 205-250 mg/dl took 240 mg of anthocyanins a day for 30 days. Before and after the period of anthocyanins administration a blood sample was taken and following parameters were estimated: lead, aluminium, cooper and zinc concentration in erythrocytes with the method of atomic emission spectrometry with induced coupling plasma (AES-ICP), concentration of substances reacting with thiobarbituric acid (TBARS) and superoxide dismutase, glutathione peroxidase and catalase activities in hemolysate.CONCLUSION: 30 days long administration of 240 mg of anthocyanins a day, caused a substantial increase of glutathione peroxidase and catalase activities. The lead, aluminium and cooper concentration was decreased while zinc concentration in red blood cells was increased. https://greenmedinfo.com/article/administration-240-mg-anthocyanins-day-30-days-caused-substantial-increase-glu#comments Anthocyanins Chokeberry High Cholesterol Oxidative Stress Aluminum Antioxidants Lead Detoxification Phytotherapy Human Study Fri, 15 May 2015 14:39:14 +0000 greenmedinfo 117456 at https://greenmedinfo.com Chlorella supplementation detoxifies heterocyclic amines in young Korean adults. https://greenmedinfo.com/article/chlorella-supplementation-detoxifies-heterocyclic-amines-young-korean-adults PMID:  Environ Toxicol Pharmacol. 2015 Jan ;39(1):441-6. Epub 2014 Dec 3. PMID: 25590673 Abstract Title:  Detoxification of chlorella supplement on heterocyclic amines in Korean young adults. Abstract:  Heterocyclic amines (HCAs) and polycyclic aromatic hydrocarbons (PAHs) have been established as carcinogenic chemicals in Western diet. This study was performed to estimate HCA exposure levels in Korean daily life and to assess the ability of Chlorella vulgaris to detoxify carcinogenic HCAs in a randomized, double blind, placebo-controlled crossover study with chlorella supplement (N=6, all females, age: 27.17±7.73yr) for 2 weeks. We analyzed HCAs in hydrolyzed urine specimens using LC/TOF-MS. As results, urinary levels of MeIQx, PhIP, and IQx-8-COOH were 323.36±220.11ng/L, 351.59±254.93ng/L, and 130.85±83.22ng/L, respectively. Effects of chlorella to reduce urinary MeIQx were marginally significant(before, 430±226.86pg/mL vs. after, 174.45±101.65pg/mL: 0.05 https://greenmedinfo.com/article/chlorella-supplementation-detoxifies-heterocyclic-amines-young-korean-adults#comments Chlorella (Algae) Heterocyclic Aromatic Amine Induced Toxicity Chemopreventive Detoxifier Detoxification Significant Treatment Outcome Human Study Fri, 10 Jul 2015 00:05:14 +0000 greenmedinfo 118876 at https://greenmedinfo.com Cleanse, Flush, Sweat, Mobilize, Chelate, Detox...and Heal https://greenmedinfo.com/blog/cleanse-flush-sweat-mobilize-chelate-detoxand-heal <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2023<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><br /> <img alt="Cleanse, Flush, Sweat, Mobilize, Chelate, Detox...and Heal" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/sayerji/images/cleanse_detox_healing.jpg" /></p><p><a href="https://greenmedinfo.com/blog/cleanse-flush-sweat-mobilize-chelate-detoxand-heal" target="_blank">read more</a></p> https://greenmedinfo.com/blog/cleanse-flush-sweat-mobilize-chelate-detoxand-heal#comments Chlorella (Algae) Heavy Metal Toxicity MSM (Methylsulfonylmethane) Organosulfur Compounds Petroleum Exposure And Toxicity Radiation Disaster Associated Toxicity Vitamin C Chelation Therapy: EDTA Chemical and Drug Toxicity Cytotoxic Detoxifier Oxidative Damage Chelation chlorella Clay Detoxification Hypoxia Inflammation Magnesium oxidative stress potassium sulfur Vitamin C Fri, 15 Sep 2023 14:58:23 +0000 forbiddenhealing 92297 at https://greenmedinfo.com Consumption of polyphenol-rich products may prevent Cadmium absorption from the diet polluted by this metal and its accumulation in the body, and thus also protect from its toxic action. https://greenmedinfo.com/article/consumption-polyphenol-rich-products-may-prevent-cadmium-absorption-diet-pollu PMID:  Curr Drug Targets. 2015 Jan 2. Epub 2015 Jan 2. PMID: 25557255 Abstract Title:  Protective Effect of Aronia Melanocarpa Polyphenols on Cadmium Accumulation in the Body: a Study in a Rat Model of Human Exposure to this Metal. Abstract:  Recently a growing attention has been paid to the possibility of using biologically active compounds, including polyphenols, for the prevention of unfavourable effects of exposure to xenobiotics. The study was aimed to investigate, in a female rat model, whether consumption of Aronia melanocarpa polyphenols (AMP) under chronic exposure to cadmium (Cd) decreases the gastrointestinal absorption and body burden of this heavy metal. For this purpose, Cd turnover (apparent absorption, retention in the body, concentration in the blood, soft tissues and bone tissue, total pool in internal organs, faecal and urinary excretion) was evaluated in the female Wistar rats who were administered only a 0.1% water extract of AMP (prepared from the powdered extract containing 65.74% of polyphenols) as drinking fluid or/and Cd in diet (1 and 5 mg/kg) for up to 24 months. AMP administration under the low Cd treatment (1 mg/kg diet) had only very slight protective impact against this metal accumulation in the organism, whereas their application under the moderate exposure (5 mg Cd/kg diet) importantly decreased the apparent absorption and retention in the body, and increased urinary concentration of this xenobiotic resulting in its lower concentration in the blood and lower accumulation in soft tissues (mainly in the liver and kidneys) and bone tissue. Based on the study it can be concluded that consumption of polyphenol-rich products may prevent Cd absorption from the diet polluted by this metal and its accumulation in the females&#039; body, and thus also protect from its toxic action. https://greenmedinfo.com/article/consumption-polyphenol-rich-products-may-prevent-cadmium-absorption-diet-pollu#comments Cadmium Poisoning Chokeberry Polyphenols Hepatoprotective Renoprotective Detoxification Animal Study Fri, 15 May 2015 04:26:52 +0000 greenmedinfo 117439 at https://greenmedinfo.com Holistic Medicine: A Life Without Fear https://greenmedinfo.com/blog/holistic-medicine-life-without-fear <p class="rtecenter"><img alt="Holistic Medicine: A Life Without Fear" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/lrossi/images/holistic_health_greenmedinfo.jpg" style="width: 600px; height: 314px;" title="Holistic Medicine: A Life Without Fear" /><br /> <span style="font-size:12px;"><strong><span style="letter-spacing: 0px;">Originally published on </span><strong style="letter-spacing: 0px;"><a href="https://kellybroganmd.com/holistic-medicine-a-life-without-fear/" rel="dofollow" target="_blank">kellybroganmd.com</a></strong></strong></span></p> <p><span style="font-size:18px;"><em><strong>There is a radically different way to think about health. You may have heard about it, but are you clear on what it truly means, and the transformations it can yield in your mind, </strong></em></span><span style="font-size:18px;"><em><strong>body</strong></em></span><span style="font-size:18px;"><em><strong> and spirit?</strong></em></span></p> <p>You can fight or you can trust.</p><p><a href="https://greenmedinfo.com/blog/holistic-medicine-life-without-fear" target="_blank">read more</a></p> https://greenmedinfo.com/blog/holistic-medicine-life-without-fear#comments Antibiotics Antibiotics Detoxification antibiotics Detoxification holistic health Holistic Medicine: A Life Without Fear Natural Healing Thu, 27 Jul 2017 15:44:47 +0000 drbrogan 150791 at https://greenmedinfo.com Is DETOX a Myth? https://greenmedinfo.com/blog/detox-myth <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2019<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><img alt="Is DETOX a Myth?" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/lrossi/images/detox_myth_gaps_greenmedinfo.png" style="width: 600px; height: 407px;" /></p> <p><em><span style="font-size:18px;"><strong>How detoxification works, and how it is approached from a GAPS™ (Gut and Psychology Syndrome) perspective.</strong></span></em></p> <p>Recently my husband brought an article from the Guardian to my attention that was titled:</p> <blockquote> <p><em><strong><a href="https://www.theguardian.com/lifeandstyle/2014/dec/05/detox-myth-health-diet-science-ignorance" rel="nofollow" target="_blank">YOU CAN'T DETOX YOUR BODY. IT'S A MYTH. SO HOW DO YOU GET HEALTHY?"</a></strong></em></p> </blockquote> <p>The article byline went on to say:</p><p><a href="https://greenmedinfo.com/blog/detox-myth" target="_blank">read more</a></p> https://greenmedinfo.com/blog/detox-myth#comments Detoxification Health Guides: Healing Foods Detoxification GAPS Protocol Is DETOX a Myth? Tue, 22 Dec 2015 17:53:40 +0000 melaniechristner 122711 at https://greenmedinfo.com Korean red ginseng lowers urinary BPA levels and BPA-induced malondialdehyde levels and alleviates gynecological complaints without side effects of raw-ginseng. https://greenmedinfo.com/article/korean-red-ginseng-lowers-urinary-bpa-levels-and-bpa-induced-malondialdehyde-l PMID:  BMC Complement Altern Med. 2014 ;14:265. Epub 2014 Jul 25. PMID: 25063041 Abstract Title:  Effects of Korean red ginseng (Panax Ginseng Meyer) on bisphenol A exposure and gynecologic complaints: single blind, randomized clinical trial of efficacy and safety. Abstract:  BACKGROUND: Korean red ginseng (KRG) is a processed ginseng from raw ginseng to enhance safety, preservation and efficacy, known having beneficial effects on women&#039;s health due to its estrogen like function. While estrogen supplementation showed some modulation of endocrine disrupting chemicals, bisphenol A (BPA) has been focused as a potential endocrine disrupting chemical. In this study, we examined the efficacy and safety outcomes of KRG against BPA, focusing on female quality of life (QOL). Individual variations in susceptibility to KRG were also investigated with the Sasang Typology, the personalized medicine used for hundred years in Korea.METHODS: We performed a single-blind randomized clinical trial. Study subjects were young women (N = 22), consumed 2.7 g of KRG or placebo per day for 2 weeks and filled up questionnaires regarding gynecologic complaints at the 4 time spots. We analyzed urinary total BPA and malondialdehyde (MDA), an oxidative stress biomarker, with GC/MS and HPLC/UVD respectively, and diagnosed their Sasang Typology with the questionnaire for the Sasang constitution Classification (QSCC II).RESULTS: KRG consumption decreased urinary BPA and MDA levels (ps https://greenmedinfo.com/article/korean-red-ginseng-lowers-urinary-bpa-levels-and-bpa-induced-malondialdehyde-l#comments Bisphenol-A Toxicity Ginseng (Korean) Oxidative Stress Bisphenol A Chemopreventive Malondialdehyde Down-regulation Detoxification Plant Extracts Human Study Thu, 28 May 2015 23:28:30 +0000 greenmedinfo 117815 at https://greenmedinfo.com Lemon detox program reduces body fat and insulin resistance through caloric restriction and might have a potential beneficial effect on risk factors for cardiovascular disease https://greenmedinfo.com/article/lemon-detox-program-reduces-body-fat-and-insulin-resistance-through-caloric-re PMID:  Nutr Res. 2015 May ;35(5):409-20. Epub 2015 Apr 10. PMID: 25912765 Abstract Title:  Lemon detox diet reduced body fat, insulin resistance, and serum hs-CRP level without hematological changes in overweight Korean women. Abstract:  The lemon detox program is a very low-calorie diet which consists of a mixture of organic maple and palm syrups, and lemon juice for abstinence period of 7 days. We hypothesized that the lemon detox program would reduce body weight, body fat mass, thus lowering insulin resistance and known risk factors of cardiovascular disease. We investigated anthropometric indices, insulin sensitivity, levels of serum adipokines, and inflammatory markers in overweight Korean women before and after clinical intervention trial. Eighty-four premenopausal women were randomly divided into 3 groups: a control group without diet restriction (Normal-C), a pair-fed placebo diet group (Positive-C), and a lemon detox diet group (Lemon-D). The intervention period was 11 days total: 7 days with the lemon detox juice or the placebo juice, and then 4 days with transitioning food. Changes in body weight, body mass index, percentage body fat, and waist-hip ratio were significantly greater in the Lemon-D and Positive-C groups compared to the Normal-C group. Serum insulin level, homeostasis model assessment insulin resistance scores, leptin, and adiponectin levels decreased in the Lemon-D and Positive-C groups. Serum high-sensitive C-reactive protein (hs-CRP) levels were also reduced only in the Lemon-D group. Hemoglobin and hematocrit levels remained stable in the Lemon-D group while they decreased in the Positive-C and Normal-C groups. Therefore, we suppose that the lemon detox program reduces body fat and insulin resistance through caloric restriction and might have a potential beneficial effect on risk factors for cardiovascular disease related to circulating hs-CRP reduction without hematological changes. https://greenmedinfo.com/article/lemon-detox-program-reduces-body-fat-and-insulin-resistance-through-caloric-re#comments Inflammation Insulin Resistance Lemon Lemon Juice Overweight Anti-Inflammatory Agents Fasting/Caloric Restriction Insulin Sensitizers Anti-Obesity Agents Detoxification Risk Reduction Human Study Fri, 26 Jun 2015 18:40:39 +0000 greenmedinfo 118513 at https://greenmedinfo.com Mainstream Medical Myths / Alternative Healing Pitfalls https://greenmedinfo.com/blog/mainstream-medical-myths-alternative-healing-pitfalls <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2015<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><img alt="Mainstream Medical Myths / Alternative Healing Pitfalls" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/chelseaj/images/MedicalMyths(1).jpg" style="font-size: 0.9em; line-height: 24.4799995422363px; width: 600px; height: 400px;" /></p> <p><span style="font-size:16px;"><em><strong>Staying healthy is hard enough without intentional disinformation.&nbsp; Basic science and logic can reveal the life-saving</strong></em></span> <span style="font-size:16px;"><em><strong>truths forbidden by our medical industrial complex and corporate media.</strong></em></span></p><p><a href="https://greenmedinfo.com/blog/mainstream-medical-myths-alternative-healing-pitfalls" target="_blank">read more</a></p> https://greenmedinfo.com/blog/mainstream-medical-myths-alternative-healing-pitfalls#comments Oxidative Stress Detoxification disease metals Toxins Vitamin C Thu, 16 Apr 2015 13:58:51 +0000 forbiddenhealing 116879 at https://greenmedinfo.com Niacin for Detoxification: A Little-known Therapeutic Use https://greenmedinfo.com/blog/niacin-detoxification-little-known-therapeutic-use <p class="rtecenter"><img alt="Niacin for Detoxification: A Little-known Therapeutic Use" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/lrossi/images/niacin_detoxification_greenmedinfo.png" style="width: 700px; height: 467px;" title="Niacin for Detoxification: A Little-known Therapeutic Use" /></p> <p><span style="font-size:22px;"><em><strong>Niacin&nbsp;augments detoxification by lowering the body burden of lipid-stored xenobiotics.</strong></em></span></p> <p><em>Republished with permission from the <a href="http://orthomolecular.org/library/jom/" target="_blank" title="Niacin for Detoxification: A Little-known Therapeutic Use">Journal of Orthomolecular Medicine</a>, Volume 26, Number 2, 2011</em></p><p><a href="https://greenmedinfo.com/blog/niacin-detoxification-little-known-therapeutic-use" target="_blank">read more</a></p> https://greenmedinfo.com/blog/niacin-detoxification-little-known-therapeutic-use#comments Liver Damage Liver Disease Niacin Vitamin B-3 (Niacin) Detoxification Detoxification liver damage Liver Disease Niacin Niacin for Detoxification: A Little-known Therapeutic Use vitamin b-3 Fri, 11 Aug 2017 16:53:29 +0000 orthmolecular1 151318 at https://greenmedinfo.com Oral administration of vitamin C and vitamin E significantly reduced the blood lead concentration, ameliorates the hepatic damage and reduces oxidative stress. https://greenmedinfo.com/article/oral-administration-vitamin-c-and-vitamin-e-significantly-reduced-blood-lead-c PMID:  Nig Q J Hosp Med. 2012 Apr-Jun;22(2):85-90. PMID: 23175903 Abstract Title:  Oral administration of vitamin C and vitamin E ameliorates lead-induced hepatotoxicity and oxidative stress in the rat brain. Abstract:  BACKGROUND: Lead toxicity is a public health concern. Lead is one of the dispensable and non-biodegradable heavy metals and is toxic even at low concentrations.OBJECTIVE: This study was to investigate the effect of oral administration of Vitamin C and Vitamin E on lead-induced hepatotoxicity and oxidative stress in the brain of rats.METHODS: Thirty Sprague-Dawley albino male albino rats (115.58 +/- 4.96g) were divided equally into five groups. The rats were fed rat chow and water ad libitum. Group 1 rats served as control and were orally administered 2ml saline every day for 7 weeks. Group 2 rats received orally 2ml lead acetate solution (60mg/kg body weight) every day for 7 weeks. Group3 rats received orally 2ml lead acetate solution (60mg/kg body weight) and vitamin C (40mg/kg body weight) every other day for 7 weeks. Group 4 rats received orally 2ml lead acetate solution (60mg/kg body weight) and vitamin E (150mg/kg body weight)every day for 7weeks. Group 5 received orally lead acetate solution at 60mg/kg body weight and vitamin C (40mg/kg body weight)and vitamin E (150mg/kg body weight) every other day for 7weeks. Three rats from each group were sacrificed after the fourth week. The remaining rats were sacrificed after the seventh week. Changes in body weight, liver weight, brain weight, activities of liver function enzymes (aspartate amino transferase (AST), alanine amino transferase (ALT) and alkaline phosphatase(ALP) in the serum at week 4 and week 7 were assayed.The oxidative stress markers (reduced glutathione (GSH), nitric oxide(NO), malondialdehyde(MDA), levels, catalase(CAT) and superoxide dismutase (SOD) activities) were determined in the brain of rats. Serum lead level of rats was also determined.RESULTS: The lead Pb exposed rats caused a significant (p https://greenmedinfo.com/article/oral-administration-vitamin-c-and-vitamin-e-significantly-reduced-blood-lead-c#comments Chemically-Induced Liver Damage Lead Poisoning Oxidative Stress Vitamin C Vitamin E Antioxidants Hepatoprotective Detoxification Significant Treatment Outcome Animal Study Wed, 01 Jul 2015 20:10:39 +0000 greenmedinfo 118625 at https://greenmedinfo.com Preventing Disease Before It Starts https://greenmedinfo.com/blog/preventing-disease-it-starts <div title="Page 1"> <div> <p class="rtecenter"><img alt="Preventing Disease Before It Starts" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/lrossi/images/preventing_disease_greenmedinfo.jpg" style="width: 700px; height: 466px;" title="Preventing Disease Before It Starts" /></p> <h2> Preventing Disease Before It Starts</h2> <p><span style="font-size:18px;"><em><strong><span style="letter-spacing: 0px;">The human body has over 60 trillion cells, and every one of them is vulnerable to the development of multiple diseases. One of the biggest problems facing medicine is how to diagnose these diseases earlier, in order to improve the chances of stopping and reversing them. </span></strong></em></span></p> <p><span style="letter-spacing: 0px;">Here are a few classic examples of the challenges of early detection. <sup>1</sup></span></p><p><a href="https://greenmedinfo.com/blog/preventing-disease-it-starts" target="_blank">read more</a></p> https://greenmedinfo.com/blog/preventing-disease-it-starts#comments Breast Cancer coenzyme Q-10 CoQ10 Diabetes Liver Cancer Vitamin D3 Cancer Exercise Health Guide: Chemical Exposures Health Guides: Healing Foods Meditation Organochlorine pesticides Yoga Breast Cancer CoQ10 Detoxification Diabetes liver cancer Preventing Disease Before It Starts Turmeric Tue, 11 Apr 2017 13:01:52 +0000 charleskbens 145718 at https://greenmedinfo.com Saffron has an extensive spectrum of protective properties against toxicities induced by either natural or chemical toxins. https://greenmedinfo.com/article/saffron-has-extensive-spectrum-protective-properties-against-toxicities-induce PMID:  Daru. 2015 ;23(1):31. Epub 2015 May 1. PMID: 25928729 Abstract Title:  Saffron as an antidote or a protective agent against natural or chemical toxicities. Abstract:  Saffron (Crocus sativus) is an extensively used food additive for its color and taste. Since ancient times this plant has been introduced as a marvelous medicine throughout the world. The wide spectrum of saffron pharmacological activities is related to its major constituents including crocin, crocetin and safranal. Based on several studies, saffron and its active ingredients have been used as an antioxidant, antiinflammatory and antinociceptive, antidepressant, antitussive, anticonvulsant, memory enhancer, hypotensive and anticancer. According to the literatures, saffron has remarkable therapeutic effects. The protective effects of saffron and its main constituents in different tissues including brain, heart, liver, kidney and lung have been reported against some toxic materials either natural or chemical toxins in animal studies.In this review article, we have summarized different in vitro and animal studies in scientific databases which investigate the antidotal and protective effects of saffron and its major components against natural toxins and chemical-induced toxicities. Due to the lake of human studies, further investigations are required to ascertain the efficacy of saffron as an antidote or a protective agent in human intoxication. https://greenmedinfo.com/article/saffron-has-extensive-spectrum-protective-properties-against-toxicities-induce#comments Acetaminophen (Tylenol) Toxicity Aluminum Toxicity Cadmium Poisoning Chemical Poisoning: Accumulated Environmental Toxins Pesticide Toxicity Saffron Cardioprotective Chemoprotective Agents Cytoprotective Hepatoprotective Neuroprotective Agents Detoxification Review Thu, 21 May 2015 14:43:22 +0000 greenmedinfo 117616 at https://greenmedinfo.com This review highlights the plausible molecular mechanisms through which phytoalexins regulate biological processes that can impinge cancer development. https://greenmedinfo.com/article/review-highlights-plausible-molecular-mechanisms-through-which-phytoalexins-re PMID:  Front Biosci (Landmark Ed). 2012 ;17:2035-58. Epub 2012 Jun 1. PMID: 22652763 Abstract Title:  Phytoalexins in cancer prevention. Abstract:  Plant phytoalexins are a class of low molecular weight compounds that accumulate in response to biotic and abiotic elicitors such as pathogens, wounding, freezing, UV light, and exposure to agricultural chemicals. Phytoalexins have been identified in at least 75 plants including cruciferous vegetables, soybean, garlic, tomato, rice, beans, and potatoes suggesting plants may be a rich source of cancer-fighting compounds. Preclinical evidence suggests these compounds possess anticancer properties including an inhibition of microbial activity, cell proliferation, invasion and metastasis, hormonal stimulation, and stimulatory effects on expression of metabolizing enzymes. This review highlights the plausible molecular mechanisms through which phytoalexins regulate biological processes that can impinge cancer development. Targets of phytoalexins include signal transduction pathways, transcription factors, cell cycle checkpoints, intrinsic and extrinsic apoptotic pathways, cell invasion and matrix metalloproteinase, nuclear receptors, and the phase II detoxification pathway. Additional research should address physiological relevant dietary concentrations, combinations of phytoalexins and interactions with other dietary compounds, duration of exposure, and tissue specificity as variables that influence the effectiveness of phytoalexins on normal and cancerous processes. https://greenmedinfo.com/article/review-highlights-plausible-molecular-mechanisms-through-which-phytoalexins-re#comments Cancer Metastasis Cancers: All Phytoalexins Anti-metastatic Anticarcinogenic Agents Antimicrobial Antiproliferative Apoptotic Enzyme Inhibitors Detoxification Review Tue, 05 May 2015 13:27:59 +0000 greenmedinfo 117147 at https://greenmedinfo.com