Polyphenols

Name	AC	CK
Oxidative Stress	123	336
Cardiovascular Diseases	51	263
Inflammation	69	214
Hypertension	28	199
Obesity	51	152
Endothelial Dysfunction	23	146
Diabetes Mellitus: Type 2	32	136
Insulin Resistance	17	97
Cancers: All	41	68
Cholesterol: Oxidation	9	65
Breast Cancer	43	62
Aging	18	61
Hyperglycemia	19	57
Cognitive Decline/Dysfunction	13	54
Atherosclerosis	14	50
Metabolic Diseases	11	49
Prostate Cancer	19	48
Lipopolysaccharide-Induced Toxicity	22	46
Arteriosclerosis	7	44
Hyperlipidemia	17	44
C-Reactive Protein	3	40
HDL: Low	4	40
Alzheimer's Disease	31	39
DNA damage	16	39
Lipid Peroxidation	16	35
High Fat Diet	17	33
Metabolic Syndrome X	14	31
Neurodegenerative Diseases	26	30
High Cholesterol	6	27
Chemically-Induced Liver Damage	13	26
Dysbiosis	5	25
Liver Cancer	15	25
Coronavirus Infection	24	24
Parkinson's Disease	19	24
Colon Cancer	19	23
Radiation Induced Illness	9	23
Ultraviolet Radiation Induced Damage	8	23
Diarrhea	3	22
HIV Infections	4	22
Dysbiosis: Bifidobacteria Deficiency	3	21
Nonalcoholic fatty liver disease (NAFLD)	8	21
All-Cause Mortality	2	20
Cholesterol: LDL/HDL ratio	2	20
Constipation	2	20
Hemodialysis	1	20
Prostate: PSA Doubling	2	20
Adiponectin: Low Levels	5	18
Brain Inflammation	11	17
Diabetes Mellitus: Type 2: Prevention	3	17
Dyslipidemias	5	17
Cardiovascular Disease	3	16
Escherichia coli Infections	6	16
Aging Skin	5	15
Dementia	6	15
Gastric Cancer	6	15
Osteoarthritis	4	15
Triglycerides: Elevated	4	15
Ulcerative Colitis	4	14
Colorectal Cancer	8	13
Memory Disorders	3	13
Alcohol Toxicity	7	12
Alcoholic Liver Disease	7	12
Breast Cancer: Triple Negative	10	12
Cervical Cancer	11	12
Chronic Kidney Disease (CKD)	2	12
Dental Caries	3	12
Depression	8	12
Diabetes: Oxidative Stress	3	12
Fatty Liver	6	12
Gallbladder Cancer	2	12
Lung Cancer	10	12
Systemic Lupus Erythematosus	2	12
Aging: Brain	5	11
Athletic Performance	2	11
Attention Deficit Hyperactivity Disorder	2	11
Cardiovascular Disease: Prevention	2	11
Colitis	6	11
Coronary Artery Disease	2	11
Diabetes: Cardiovascular Illness	2	11
Diabetic Complications	7	11
Erectile Dysfunction	2	11
Helicobacter Pylori Infection	2	11
Human T-Cell Lymphotrophic Virus type 1 associated disease	2	11
Prostate Cancer: Prevention	2	11
Sarcopenia	2	11
Sleep Disorders	2	11
Smoking	2	11
AIDS	1	10
Adult T-cell leukemia/lymphoma (ATL)	1	10
Advanced Glycation End products (AGE)	9	10
Aflatoxicosis	1	10
Angina Pectoris	1	10
Arterial Thickening	1	10
Bile Duct Cancer	1	10
Blood Pressure: High	1	10
Cancers: Drug Resistant	9	10
Carotid Artery Narrowing	1	10
Chronic Disease	1	10
Chronic Pelvic Pain Syndrome	1	10
Common Cold	1	10
Dermatitis: Contact	1	10
Diarrhea: in Children	1	10
Exercise-Induced Tissue Damage	1	10
Fibromyalgia	1	10
Gastroenteritis	1	10
Gulf War Syndrome	1	10
Heart Disease: Ischemic	1	10
Hypoxia	1	10
Intima Media Thickening	1	10
Libido: Low	1	10
Lung Cancer: Prevention	1	10
Muscle Damage: Exercise-Induced	1	10
Myocardial Infarction	5	10
Neurofibromatosis	1	10
Obesity: Abdominal	1	10
Osteopenia	1	10
Overweight	1	10
Peripheral Arterial Disease	1	10
Postmenopausal Disorders: Weight Gain/Obesity	1	10
Prostatitis: Acute	1	10
Pulmonary Diseases	1	10
Rotavirus Infections	1	10
Sepsis	4	10
Sexaul Dysfunction	1	10
Chemotherapy-Induced Toxicity: Cisplatin	6	9
Endometriosis	6	9
Inflammatory Bowel Diseases	7	9
Liver Damage: Drug-Induced	5	9
Osteoporosis	6	9
Breast Cancer: Metastatic	4	8
Cadmium Poisoning	4	8
Hyperuricemia	4	8
Pancreatic Cancer	6	8
Staphylococcus aureus infection	8	8
Hypercholesterolemia	4	7
Acetaminophen (Tylenol) Toxicity	3	6
Allergies	4	6
Cancer Metastasis	5	6
Cancers	2	6
Cerebral Ischemia	3	6
Colorectal Cancer: Prevention	2	6
Diabetic Nephropathy	3	6
Endotoxemia	3	6
Food Allergies	3	6
High Sugar Diet	3	6
Immune Disorders: Low Immune Function	3	6
Liver Damage	4	6
Melanoma	5	6
Periodontitis	4	6
Aging: Immunosenecence	3	5
Anti-gliadin Antibodies: Elevated	1	5
Endothelial Damage	1	5
Food Allergies: Wheat	1	5
Glioma	4	5
Hypertension: Pulmonary	1	5
Kidney Damage	2	5
Kidney Damage: Chemically-Induced	3	5
Steptococcus Mutans Infections	5	5
Air Pollution Linked Toxicity	3	4
Aluminum Toxicity	2	4
Amyotrophic Lateral Sclerosis	4	4
Brain: Oxidative Stress	3	4
Breast Cancer: Lung Metastasis	2	4
Carcinoma: Non-Small-Cell Lung	3	4
Chemotherapy-Induced Kidney Damage	2	4
Colon Cancer: Prevention	3	4
Coronavirus Disease (Covid-19)	4	4
Diabetes Mellitus: Type 1	2	4
Diabetic Retinopathy	3	4
Gastric Ulcer	2	4
Gastrointestinal Inflammation	3	4
High Fructose Diet	2	4
Hyperinsulinism	2	4
Hypothyroidism	2	4
Irritable Bowel Syndrome	2	4
Lung Injury: Acute	2	4
Multiple Sclerosis	4	4
Oral Cancer	4	4
Periodontal Diseases	3	4
Pseudomonas aeruginosa	4	4
Stress	2	4
Acrylamide-induced toxicity	2	3
Bladder Cancer	3	3
Brain Ischemia	2	3
Cataract	2	3
Cholera	2	3
Drug-Induced Toxicity: Indomethacin	2	3
Esophageal Cancer	3	3
Fluoride Toxicity	1	3
Glioblastoma	3	3
High Homocysteine	2	3
Human Papillomavirus (HPV)	3	3
Influenza	2	3
Influenza A	3	3
Kidney Damage: Drug-Induced	2	3
Liver Fibrosis	2	3
MRSA	2	3
Muscle Atrophy	2	3
Neuroblastoma	3	3
Osteosarcoma	3	3
Phthalate Toxicity	2	3
Radiation	2	3
Skin Cancer	3	3
Snake Bite: Venom Toxicity	2	3
Acute lymphoblastic leukemia (ALL)	2	2
Alopecia	1	2
Anaphylaxis	1	2
Aneurysm: Aortic	1	2
Antibiotic Toxicity	1	2
Arsenic Poisoning	2	2
Arthritis	1	2
Atopic Dermatitis	1	2
Autoimmune Diseases	1	2
Brain Injury: Hippocampal Damage	1	2
Cachexia	1	2
Cancers: Multi-Drug Resistant	2	2
Cancers: Radiation-Resistant	1	2
Cardiac Hypertrophy	1	2
Chemical Exposure: Nitrobenzene	1	2
Chemotherapy-Induced Toxicity: Doxorubicin	2	2
Chemotherapy-Induced Toxicity: Irinotecan	1	2
Clostridium Infections	2	2
Dermatitis	1	2
Diabetes: Cognitive Dysfunction	1	2
Diabetic Neuropathy	1	2
Diesel Exhaust Particle Toxicity	1	2
Dioxin Toxicity	1	2
Drug-Induced Toxicity: Cyclosporine	1	2
Ehrlich carcinoma	1	2
Eye Diseases	2	2
Fatigue: Excercise-Induced	1	2
Female	1	2
Fructose-Induced Toxicity	1	2
Gestational Diabetes	1	2
Giardiasis	2	2
Glaucoma	2	2
Hair Loss	1	2
Hashimoto's thyroiditis	1	2
Heart Failure	1	2
Heavy Metal Toxicity	1	2
Herpes Simplex Virus Type 1	2	2
Hydrogen Peroxide Induced Toxicity	2	2
Hypersensitivity	1	2
Hypertension: Arterial	1	2
Hypoglycemia	2	2
IgA Deficiency	1	2
IgE-Mediated Hypersensitivity	1	2
Infertility: Aging Associated	1	2
Infertility: Female	1	2
Intestinal Diseases	1	2
Kidney Failure	1	2
Leukemia: Acute promyelocytic leukemia	1	2
Liver Damage: Aflatoxin-Induced	1	2
Liver Injury: Ischemia/reperfusion	1	2
Low Immune Function: Thymus Dysfunction	1	2
Lung Inflammation	1	2
Lymphoma	1	2
Melanoma: Metastatic	1	2
Mitochondrial Dysfunction	2	2
Muscle Damage	1	2
Mycobacterium Tuberculosis	2	2
Myocarditis: Autoimmune	1	2
Nasopharyngeal Cancer	2	2
Neurologic Disorders	2	2
Ovariectomy Associated Adverse Changes	1	2
Pesticide Toxicity	2	2
Petroleum Exposure And Toxicity	1	2
Prostatic Hyperplasia: Benign	1	2
Psychiatric Disorders	2	2
Radiation Induced Illness: Bone Marrow	1	2
Retinal Degeneration: Light-Induced	2	2
Rheumatoid Arthritis	1	2
Schizophrenia	2	2
Silicosis	1	2
Skin Diseases: Photo-Aging	2	2
Surgery: Anesthesiology	1	2
Testicular Injury: Chemical/Metal Induced	1	2
Tetanus	1	2
Tumors	1	2
Vaccine-induced Toxicity	1	2
Wound Healing	1	2
Acute Myeloid Leukemia	1	1
Asbestos Toxicity	1	1
Aspergillosis	1	1
Attention Deficit Disorder	1	1
Autism Spectrum Disorders	1	1
Bacterial Infections: Resistance/Biofilm Formation	1	1
Barrett Esophagus	1	1
Benzene Toxicity	1	1
Bisphenol Toxicity	1	1
Bladder Cancer: Prevention	1	1
Brain: Microglial Activation	1	1
Breast Cancer: HER-2 Overexpressed	1	1
Candida Albicans	1	1
Candida Infection	1	1
Cardiomyopathy	1	1
Chemotherapy-Induced Toxicity: Bleomycin	1	1
Chlamydia Infections	1	1
Chronic Obstructive Pulmonary Disease	1	1
Clotting	1	1
Covid: Long	1	1
Crohn's Disease	1	1
Cryptosporidiosis	1	1
Dengue	1	1
Diabetes	1	1
Diabetes Mellitus: Type 1: Prevention	1	1
Diabetes: Eye Disease	1	1
Down Syndrome	1	1
Drug-Induced Toxicity: Gastrointestinal	1	1
Duchenne's Muscular Dystrophy	1	1
Ebola Virus Infections	1	1
Electromagnetic Radiation Mitigation	1	1
Enterobacteriaceae Infections	1	1
Epithelial Neoplasms: Malignant	1	1
Excitotoxicity	1	1
Eye Damage	1	1
Foodborne Pathogens: Prevention/Food Preservation	1	1
Fusobacterium Infections	1	1
Gram-Negative Bacterial Infections	1	1
H3N2 Infection	1	1
H5N1 Infection	1	1
Hepatoma	1	1
Herpes Simplex Virus Type 2	1	1
Hyperpigmentation	1	1
Infection: Antibiotic Resistant	1	1
Infertility	1	1
Insomnia	1	1
Iron Overload	1	1
Kidney Cancer	1	1
Leishmaniasis	1	1
Leukemia	1	1
Leukemia: Chronic Lymphocytic Leukemia (CLL)	1	1
Leukemia: Chronic myelogenous leukemia (CML)	1	1
Listeria Infections	1	1
Liver Disease	1	1
Lung Damage	1	1
Macular Degeneration	1	1
Malaria	1	1
Malignant Melanoma	1	1
Measles	1	1
Medulloblastoma	1	1
Mercury Poisoning	1	1
Mesothelioma	1	1
Multiple Myeloma	1	1
Neurological Disorders	1	1
Neuromuscular Diseases	1	1
Norovirus	1	1
Ovarian Cancer	1	1
Pancreatitis	1	1
Photooxidative Stress	1	1
Promyelocytic leukemia	1	1
Protozoan Infections	1	1
Psoriasis	1	1
Salmonella Infections	1	1
Sickle Cell Anemia	1	1
Staphylococcal Infections	1	1
Staphylococcus aureus: Methicillin-resistant (MRSA)	1	1
Stroke	1	1
Stroke: Ischemic	1	1
Sugar (Sucrose) Toxicity	1	1
Tertiary butyl hydroperoxide toxicity	1	1
Thrombosis	1	1
Urinary Tract Infections	1	1
Vibrio Infections	1	1
Vitamin A Deficiency	1	1
Zinc Deficiency	1	1

Name	AC	CK
Antioxidants	318	744
Anti-Inflammatory Agents	197	455
Neuroprotective Agents	91	198
Antihypertensive Agents	22	157
Gastrointestinal Agents	47	154
Cardioprotective	37	140
Antiproliferative	94	132
Hypolipidemic	35	110
Tumor Necrosis Factor (TNF) Alpha Inhibitor	58	109
Interleukin-6 Downregulation	48	105
Apoptotic	79	100
Chemopreventive	49	99
Hepatoprotective	47	88
Hypoglycemic Agents	37	87
NF-kappaB Inhibitor	39	82
Interleukin-1 beta downregulation	32	71
Immunomodulatory	21	66
Anticholesteremic Agents	12	65
Cell cycle arrest	35	54
Superoxide Dismutase Up-regulation	14	49
Anti-Apoptotic	24	44
Antiviral Agents	34	44
Anticarcinogenic Agents	22	41
Insulin Sensitizers	7	37
Anti-Bacterial Agents	24	35
Anti-metastatic	29	35
Vasodilator Agents	5	35
Nrf2 activation	14	33
Chemotherapeutic	10	32
MicroRNA modulator	17	31
Radioprotective	13	29
Gastroprotective	8	28
Malondialdehyde Down-regulation	10	27
Anti-atherogenic	5	26
Cyclooxygenase 2 Inhibitors	17	26
Renoprotective	13	26
Antineoplastic Agents	19	25
Photoprotective	7	22
Tumor Suppressor Protein p53 Upregulation	9	19
Heme oxygenase-1 up-regulation	5	17
Cytoprotective	8	14
Matrix metalloproteinase-2 (MMP-2) inhibitor	9	14
Prophylactic Agents	4	14
Anti-Allergic Agents	6	13
Antimicrobial	12	13
Chemoprotective Agents	9	13
Enzyme Inhibitors	11	13
Regenerative	11	13
Antidiarrheals	2	12
Antioxidant	3	12
Angiotensin-Converting Enzyme Inhibitors	2	11
Anti-Glycation Agents	10	11
Insulin-releasing	2	11
Nitric Oxide Enhancer	2	11
P21 Activation	2	11
Adiponectin Down-Regulation	1	10
Adiponectin upregulation	4	10
Alpha-glucosidase inhibitor	9	10
Angiogenesis Inhibitors	5	10
Antidepressive Agents	6	10
Chondroprotective	1	10
Hepatocyte growth factor (HGF) inhibitor	1	10
Laxative	1	10
Matrix metalloproteinase-9 (MMP-9) inhibitor	7	10
Osteoprotective	7	10
Vascular Endothelial Growth Factor Inhibitors	4	10
Vascular Endothelial Growth Factor Regulator	1	10
Brain-derived neurotrophic factor modulator	5	9
Chemosensitizer	9	9
Genoprotective	7	9
Nitric Oxide Inhibitor	5	7
Anti Inflammatory	2	6
Interleukin-10 upregulation	3	6
Neurogenesis	2	6
Alpha-amylase inhibitor	5	5
Anti-Fibrotic	3	5
Antilipemic Agents	1	5
Antioxidant Effects	1	5
Glucagon Like peptide 1 (GLP-1) Up-regulation	1	5
Anti-Ulcer Agents	2	4
Bcl-2 protein down-regulation	3	4
Cyclooxygenase Inhibitors	2	4
Interleukin-10 downregulation	2	4
Interleukin-12 downregulation	2	4
Interleukin-4 downregulation	2	4
Interleukin-8 downregulation	4	4
Pancreato Protective Agents	2	4
Acetylcholinesterase Inhibitor	3	3
Analgesics	2	3
Anti-Angiogenic	3	3
Anti-Tumor	2	3
Chelating Agents	2	3
Epidermal growth factor receptor (EGFR) inhibitor	2	3
Estrogen Receptor Modulators	2	3
Matrix metalloproteinase-1 (MMP-1) inhibitor	2	3
Quorum Sensing Inhibition	3	3
Radiosensitizer	2	3
STAT3 Inhibitor	3	3
Wnt/β-catenin signaling pathway modulation	2	3
Anti-Adipogenic	1	2
Anticoagulants	2	2
Antifungal Agents	2	2
Antimutagenic Agents	2	2
Autophagy Inhibitors	1	2
Bax/Bcl2 Ratio: Decrease	1	2
Bone Density Conservation Agents	1	2
Caspase-3 Activation	1	2
Catalase Up-Regulation	1	2
Cyclin D1 Down-Regulation	2	2
Dermatologic Agents	1	2
Gluconeogenesis Inhibitor	2	2
Histone deacetylase inhibitor	2	2
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	2	2
Immunostimulatory	1	2
Interferon Gamma Reducer	1	2
Interleukin-18 down-regulation	1	2
Interleukin-2 Downregulation	1	2
Interleukin-5 downregulation	1	2
Leptin Down-Regulation	1	2
Matrix Metalloproteinase-13 (MMP-13) Inhibitor	1	2
Matrix Metalloproteinases Inhibitors	1	2
Matrix metalloproteinase-3 (MMP-3) inhibitor	1	2
Neuritogenic	2	2
Neuroplasticity enhancement	1	2
Phase II Detoxification Enzyme Inducer	1	2
Postaglandin PGE2 downregulation	1	2
Proteasome Inhibitors	2	2
SIRT1 Activator	1	2
Topoisomerase II Inhibitor	2	2
Tyrosinase inhibitors	2	2
Vascular Cell Adhesion Molecule-1 Inhibitor	2	2
angiogenesis	1	2
interleukin-13 down-regulation	1	2
AMP-activated protein kinase modulation	1	1
Anti-HIV Agents	1	1
Anti-Infective Agents	1	1
Anti-Platelet	1	1
Antigiardial agents	1	1
Antiparasitic Agents	1	1
Antiprotozoal Agents	1	1
Bax/Bcl2 ratio: Increase	1	1
Cyclooxygenase 1 Inhibitor	1	1
DNA Repair Up-regulation	1	1
E-cadherin down-regulation	1	1
Fertility Agents	1	1
Forkhead Transcription Factor Family O (FOXO) Modulator	1	1
Glucose Uptake Optimization	1	1
Glutathione Upregulation	1	1
Heat Shock Protein Inducer	1	1
Hypnotics and Sedatives	1	1
Interleukin-1 alpha downregulation	1	1
Iron Chelating Agents	1	1
Leishmanicidal	1	1
Leukotriene Antagonists	1	1
Matrix metalloproteinase-14 (MMP-14) inhibitor	1	1
Matrix metalloproteinase-16 (MMP-16) inhibitor	1	1
Matrix metalloproteinase-17 (MMP-17) inhibitor	1	1
Matrix metalloproteinase-8 (MMP-8) inhibitor	1	1
NF-E2-Related Factor-2 (Nrf2) Modulator	1	1
Neurominidase Inhibitor	1	1
Protease Inhibitors	1	1
Transforming growth factor beta (TGF-β) inhibitor	1	1
Tumor Suppressor Protein p73 Upregulation	1	1
Vascular Endothelial Growth Factor A Inhibitor	1	1
Xanthine oxidase inhibitor	1	1

[+]

Hawthorn polyphenol extract could be used as a functional food component in the adjuvant treatment of T2D.Mar 31, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Evid Based Complement Alternat Med. 2012 ;2012:480714. Epub 2011 Oct 15. PMID: 22013489

Article Published Date : Dec 31, 2011

Study Type : Animal Study

Additional Links

Substances : Phellinus Linteus, Polyphenols

Diseases : Chemically-Induced Liver Damage, Inflammation, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Hepatoprotective, Matrix metalloproteinase-9 (MMP-9) inhibitor

[+]

Hispolon suppresses metastasis via autophagic degradation of cathepsin S in cervical cancer cells.Jan 04, 2017

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Pubmed Data : Cell Death Dis. 2017 10 5 ;8(10):e3089. Epub 2017 Oct 5. PMID: 28981104

Article Published Date : Jan 04, 2017

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Phellinus Linteus, Polyphenols

Diseases : Cervical Cancer

Pharmacological Actions : Anti-metastatic, Apoptotic, Cell cycle arrest

[+]

[+]

Kolaviron possibly possesses significant antihypertensive effect.May 10, 2021

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Pubmed Data : J Complement Integr Med. 2021 May 11. Epub 2021 May 11. PMID: 33977689

Article Published Date : May 10, 2021

Study Type : Animal Study

Additional Links

Substances : Garcinia kola, Polyphenols

Diseases : Hypertension

Pharmacological Actions : Antihypertensive Agents, Antioxidants, Hypolipidemic

[+]

kombucha consumption may be beneficial to intestinal health.Dec 07, 2022

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[+]

Mango polyphenolics might be relevant as preventive agents in ulcerative colitis.Apr 05, 2016

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Pubmed Data : Mol Carcinog. 2016 Apr 6. Epub 2016 Apr 6. PMID: 27061150

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Pubmed Data : Biofactors. 2008;33(1):13-24. PMID: 19276533

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Pubmed Data : Folia Neuropathol. 2019 ;57(4):327-334. PMID: 32337945

Article Published Date : Dec 31, 2018

Study Type : Animal Study

Additional Links

Substances : Polyphenols

Diseases : Brain Inflammation , Inflammation, Oxidative Stress, Sepsis

Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, NF-kappaB Inhibitor

[+]

Myricitrin blocks activation of NF-κB and MAPK signaling pathways to protect nigrostriatum neuron in LPS-stimulated mice.Jan 14, 2019

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Pubmed Data : Anticancer Res. 2016 Jul ;36(7):3705-13. PMID: 27354644

Article Published Date : Jun 30, 2016

Polyphenol extract of Moringa oleifera leaves alleviates colonic inflammation. Dec 31, 2019

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Pubmed Data : Evid Based Complement Alternat Med. 2020 ;2020:6295402. Epub 2020 Nov 24. PMID: 33299453

Article Published Date : Dec 31, 2019

Study Type : Animal Study

Additional Links

Substances : Moringa oleifera, Polyphenols

Diseases : Gastrointestinal Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents

[+]

Polyphenol-rich açaí seed extract exhibits reno-protective and anti-fibrotic activities.Dec 01, 2022

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Pubmed Data : Avicenna J Phytomed. 2018 Jan-Feb;8(1):73-84. PMID: 29387575

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : Coconut Oil, Polyphenols

Diseases : Cadmium Poisoning

Pharmacological Actions : Antioxidants, Cardioprotective

Problem Substances : Cadmium

[+]

Polyphenols potentiate dietary restriction-induced lifespan extension.Jan 11, 2012

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Pubmed Data : Biochim Biophys Acta. 2012 Jan 11 ;1822(4):522-526. Epub 2012 Jan 11. PMID: 22265987

Article Published Date : Jan 11, 2012

Study Type : Animal Study

Additional Links

Substances : Blueberry, Green Tea, Polyphenols, Pomegranate

Diseases : Aging

Therapeutic Actions : Fasting/Caloric Restriction

Pharmacological Actions : Anti-Inflammatory Agents

[+]

[+]

Potential effect of polyphenolic-rich fractions of corn silk on protecting endothelial cells against high glucose damage.Jun 15, 2021

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Pubmed Data : Molecules. 2021 Jun 16 ;26(12). Epub 2021 Jun 16. PMID: 34208534

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Pubmed Data : Molecules. 2022 Jun 25 ;27(13). Epub 2022 Jun 25. PMID: 35807346

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Pubmed Data : J Nutr. 2002 Jun ;132(6):1376-9. PMID: 12042461

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Pubmed Data : Stem Cell Res Ther. 2015 ;6(1):182. Epub 2015 Sep 22. PMID: 26395574

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Pubmed Data : PLoS One. 2011 ;6(10):e25878. Epub 2011 Oct 7. PMID: 22016781

Article Published Date : Dec 31, 2010

Study Type : Animal Study

Additional Links

Substances : Polyphenols, Strawberry

Diseases : Alcohol Toxicity , Lipid Peroxidation

Pharmacological Actions : Antioxidants, Gastroprotective, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation

Additional Keywords : Plant Extracts

[+]

Structural characteristics and hypolipidemic activity of theabrownins from dark tea fermented.Jan 29, 2020

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Pubmed Data : Biomolecules. 2020 01 30 ;10(2). Epub 2020 Jan 30. PMID: 32019226

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Pubmed Data : Oxid Med Cell Longev. 2019 ;2019:9417498. Epub 2019 Mar 21. PMID: 31015892

Article Published Date : Dec 31, 2018

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Pubmed Data : Plant Foods Hum Nutr. 2023 Sep ;78(3):512-519. Epub 2023 Jul 18. PMID: 37462847

Article Published Date : Aug 31, 2023

Study Type : Animal Study

Additional Links

Substances : Polyphenols, Strawberry

Diseases : Diabetes Mellitus: Type 2, Obesity

Pharmacological Actions : Antioxidants, Hypoglycemic Agents, Hypolipidemic

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The plant polyphenols genistein and resveratrol preserve ovarian follicular function in aging rats.Aug 01, 2010

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Pubmed Data : Biochem Cell Biol. 2010 Aug;88(4):737-45. PMID: 20651847

Article Published Date : Aug 01, 2010

Study Type : Animal Study

Additional Links

Substances : Flavonoids, Genistein, Polyphenols, Resveratrol

Diseases : Aging, Infertility: Aging Associated, Infertility: Female

Additional Keywords : Plant Extracts, Stilbenes

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Pubmed Data : J Agric Food Chem. 2015 Jul 8 ;63(26):6051-8. Epub 2015 Jun 24. PMID: 26073629

This study showed that theabrownin was a potential therapeutic modality for obesity and other metabolic disorders.Nov 22, 2020

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Pubmed Data : Metabolites. 2020 Nov 23 ;10(11). Epub 2020 Nov 23. PMID: 33238385

Article Published Date : Nov 22, 2020

Study Type : Animal Study

Additional Links

Substances : Black Tea, Polyphenols

Diseases : High Fat Diet, Obesity

Pharmacological Actions : Gastrointestinal Agents

Additional Keywords : Anti-Obesity Agents

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This suggested that polyphenol-rich by-products might provide a similar health effect in high-fat diet individuals.Mar 31, 2020

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Pubmed Data : Food Funct. 2020 Apr 1 ;11(4):3167-3179. Epub 2020 Mar 24. PMID: 32208477

Article Published Date : Mar 31, 2020

Study Type : Animal Study

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Substances : Blueberry, Fermented Foods and Beverages, Polyphenols

Diseases : High Fat Diet, Obesity

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Vaccinium uliginosum could be a potential anticataract agent in age-related cataract.Dec 31, 2018

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Pubmed Data : Mol Vis. 2019 ;25:118-128. Epub 2019 Feb 8. PMID: 30820147

Article Published Date : Dec 31, 2018

Study Type : Animal Study

Additional Links

Substances : Polyphenols

Diseases : Cataract, Oxidative Stress

Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation

Problem Substances : Sodium Selenite

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Additional Keywords : Natural Substance Synergy

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Walnut polyphenols prevent chemically-induced liver damage . Jun 25, 2008

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Pubmed Data : J Agric Food Chem. 2008 Jun 25;56(12):4444-9. Epub 2008 May 22. PMID: 18494495

Article Published Date : Jun 25, 2008

Study Type : Animal Study

Additional Links

Substances : Flavonoids, Polyphenols, Tannic Acid, Walnut

Diseases : Chemically-Induced Liver Damage

Pharmacological Actions : Hepatoprotective

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White peony polyphenols are high-quality natural products with liver protective effects.Oct 30, 2019

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Zingerone produced marked improvement in stress induced irritable bowel disorderMar 14, 2014

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Pubmed Data : Phytomedicine. 2014 Mar 15 ;21(4):423-9. Epub 2013 Nov 18. PMID: 24262066

Article Published Date : Mar 14, 2014

Study Type : Animal Study

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Substances : Ginger, Polyphenols

Diseases : Irritable Bowel Syndrome, Oxidative Stress

Pharmacological Actions : Antioxidants

Additional Keywords : Phytotherapy, Plant Extracts

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Zingerone protected the rat's heart against isoproterenol-induced myocardial infarction.Jan 31, 2015

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Pubmed Data : J Biochem Mol Toxicol. 2015 Feb ;29(2):63-9. Epub 2014 Sep 30. PMID: 25271244

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Pubmed Data : Crit Rev Food Sci Nutr. 2020 ;60(4):597-625. Epub 2019 Jan 7. PMID: 30614258

Article Published Date : Dec 31, 2019

Study Type : Review

Additional Links

Substances : Grape, Polyphenols

Diseases : Aging: Brain

Pharmacological Actions : Neuroprotective Agents

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A grape seed extract rich in procyanidins achieves direct and indirect (i.e. cell-mediated) protection of LDL against oxidation.May 01, 2003

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Pubmed Data : Free Radic Res. 2003 May;37(5):573-84. PMID: 12797479

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Pubmed Data : Environ Toxicol Pharmacol. 2014 May ;37(3):1090-100. Epub 2014 Apr 18. PMID: 24780533

Article Published Date : Apr 30, 2014

Study Type : Review

Additional Links

Substances : Algae, Polyphenols, Seaweed

Diseases : Cancers: All, Cardiovascular Diseases, Inflammation, Neurologic Disorders

Additional Keywords : Matrix Metalloproteinase Inhibitors

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A review evaluating the modulation of miRNAs by dietary agents, which could potentially be exploited for inhibition of mutagenesis and carcinogenesis.Sep 30, 2012

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Pubmed Data : Mutat Res. 2012 Oct-Dec;751(2):287-303. Epub 2012 Jun 7. PMID: 22683846

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Pubmed Data : Molecules. 2016 ;21(4). Epub 2016 Apr 21. PMID: 27110749

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Pubmed Data : Nutrients. 2016 Nov 17 ;8(11). Epub 2016 Nov 17. PMID: 27869665

Article Published Date : Nov 16, 2016

Study Type : Review

Additional Links

Substances : Carnosic Acid, Polyphenols, Rosemary, Rosmarinic acid

Diseases : Cancers: All

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Antiproliferative

Additional Keywords : Phytotherapy, Plant Extracts

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A review of the role of some commonly investigated phytochemicals and their epigenetic targets that are of particular interest in cancer prevention and cancer therapy.Nov 30, 2014

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Pubmed Data : Cancer Lett. 2014 Dec 1 ;355(1):9-17. Epub 2014 Sep 16. PMID: 25236912

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Pubmed Data : Biosci Biotechnol Biochem. 2008 Dec;72(12):3211-8. Epub 2008 Dec 7. PMID: 19060403

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Pubmed Data : J Agric Food Chem. 2009 Sep 23;57(18):8282-9. PMID: 19694434

Anti-inflammatory activity of olive oil polyphenols.Nov 20, 2022

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Pubmed Data : Biomedicines. 2022 Nov 21 ;10(11). Epub 2022 Nov 21. PMID: 36428559

Article Published Date : Nov 20, 2022

Study Type : In Vitro Study

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Substances : Olive Oil, Polyphenols

Diseases : Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 1 Inhibitor, Cyclooxygenase 2 Inhibitors

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Anti-inflammatory and neuroprotective polyphenols derived from the European olive tree, Olea europaea L., in long COVID and other conditions involving cognitive impairment.Oct 13, 2024

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Pubmed Data : Int J Mol Sci. 2024 Oct 14 ;25(20). Epub 2024 Oct 14. PMID: 39456822

Article Published Date : Oct 13, 2024

Study Type : Review

Additional Links

Substances : Polyphenols

Diseases : Alzheimer's Disease, Covid: Long, Multiple Sclerosis, Parkinson's Disease

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents

Additional Keywords : Long Covid, Plant Extracts

[+]

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Pubmed Data : Int J Mol Sci. 2022 Aug 19 ;23(16). Epub 2022 Aug 19. PMID: 36012645

Article Published Date : Aug 18, 2022

Study Type : In Vitro Study

Additional Links

Substances : Polyphenols, Reishi Mushroom

Diseases : Breast Cancer

Pharmacological Actions : Antineoplastic Agents, Antioxidants

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Anticancer effect of pomegranate peel polyphenols against cervical cancer. Jan 04, 2023

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Pubmed Data : Nutrients. 2023 Jun 11 ;15(12). Epub 2023 Jun 11. PMID: 37375613

Article Published Date : Jun 10, 2023

Study Type : In Vitro Study

Additional Links

Substances : Polyphenols, Pomegranate

Diseases : Breast Cancer, Cancers: All, Colorectal Cancer, Inflammation, Liver Cancer, Oxidative Stress, Steptococcus Mutans Infections

Pharmacological Actions : Anti-Inflammatory Agents, Antimicrobial, Antioxidants, Apoptotic

Additional Keywords : Plant Extracts

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Antioxidant, antimicrobial activities and characterization of polyphenol-enriched extract of Egyptian celery.Jan 20, 2022

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Pubmed Data : Molecules. 2022 Jan 21 ;27(3). Epub 2022 Jan 21. PMID: 35163963

Article Published Date : Jan 20, 2022

Study Type : In Vitro Study

Additional Links

Substances : Celery, Flavonoids, Polyphenols

Diseases : Escherichia coli Infections, Staphylococcus aureus infection

Pharmacological Actions : Antimicrobial, Antioxidants

Additional Keywords : Plant Extracts

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Antiproliferative activity of the olive extract rich in polyphenols and modified pectin on bladder cancer cells.Jan 14, 2020

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Pubmed Data : J Med Food. 2020 Jan 15. Epub 2020 Jan 15. PMID: 31939715

Article Published Date : Jan 14, 2020

Study Type : In Vitro Study

Additional Links

Substances : Olive, Pectin, Polyphenols

Diseases : Bladder Cancer

Pharmacological Actions : Antiproliferative

Additional Keywords : Plant Extracts, Polysaccharides

[+]

Antiproliferative and antimicrobial effects of Rosmarinus officinalis loaded liposomes.Jun 20, 2022

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Pubmed Data : Molecules. 2022 Jun 21 ;27(13). Epub 2022 Jun 21. PMID: 35807229

Artichoke polyphenols sensitize human breast cancer cells to chemotherapeutic drugs.Dec 31, 2019

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Pubmed Data : Oxid Med Cell Longev. 2020 ;2020:7965435. Epub 2020 Jan 6. PMID: 31998443

Article Published Date : Dec 31, 2019

Study Type : In Vitro Study

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Substances : Artichoke, Polyphenols

Diseases : Breast Cancer

Pharmacological Actions : Chemosensitizer

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At least five servings of vegetables and fruit daily appear protective against breast cancer recurrence. Dec 31, 2015

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Pubmed Data : Nutrients. 2016 ;8(9). Epub 2016 Sep 6. PMID: 27608040

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Pubmed Data : FEMS Yeast Res. 2010 Aug 1;10(5):570-8. Epub 2010 Apr 23. PMID: 20528949

Article Published Date : Aug 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Curcumin, Flavonoids, Polyphenols, Vitamin C

Diseases : Candida Infection

Pharmacological Actions : Antifungal Agents, Antioxidants, Apoptotic

Additional Keywords : Drug Synergy

[+]

Curcumin, quercetin, catechins and metabolic diseases: The role of gut microbiota.Jan 11, 2021

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Pubmed Data : Oxid Med Cell Longev. 2015;2015:217258. Epub 2015 Jul 8. PMID: 26236423

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Res Int. 2015 ;2015:850902. Epub 2015 Feb 22. PMID: 25793210

Article Published Date : Dec 31, 2014

Study Type : Review

Additional Links

Substances : Polyphenols

Diseases : Dysbiosis, Dysbiosis: Bifidobacteria Deficiency

Pharmacological Actions : Gastrointestinal Agents

Additional Keywords : Microbiota

[+]

Dietary polyphenols rutin, taxifolin and quercetin related compounds target Leishmania amazonensis arginase.Jun 18, 2019

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Pubmed Data : Food Funct. 2019 Jun 19 ;10(6):3172-3180. PMID: 31134235

Article Published Date : Jun 18, 2019

Study Type : In Vitro Study

Additional Links

Substances : Flavonoids, Polyphenols, Quercetin, Rutin

Diseases : Leishmaniasis

Pharmacological Actions : Leishmanicidal

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View the Evidence: 1003 Abstracts with Polyphenols Research

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Hawthorn polyphenol extract could be used as a functional food component in the adjuvant treatment of T2D.Mar 31, 2021

Hawthorn polyphenol extract inhibits UVB-induced skin photoaging.Aug 14, 2018

Hepato and Nephro protective potentials of lyophilized juice of Citrus reticulata L. fruit against paracetamol induced toxicity in rats.Apr 30, 2024

Hepatoprotective effects of zingerone on carbon tetrachloride- and dimethylnitrosamine-induced liver injuries in rats.Jan 31, 2016

Hibiscus sabdariffa exerts effects similar to those of linagliptin, which improves insulin resistance and epithelial to mesenchymal transition.Oct 07, 2014

Hispolon protects rats from liver damage from carbon tetrachloride.Dec 31, 2011

Hispolon suppresses metastasis via autophagic degradation of cathepsin S in cervical cancer cells.Jan 04, 2017

Hot-processed virgin coconut oil abrogates cisplatin-induced nephrotoxicity.Apr 30, 2022

Incorporating polyphenol-enriched Oriental plum into a high-cholesterol diet can ameliorate some of the symptoms of neurodegenerative conditions.Apr 12, 2015

Increasing doses of blueberry polyphenols alters colonic metabolism and calcium absorption in ovariectomized rats. May 31, 2020

Ingestion of pomegranate polyphenols is associated with inhibition of x-ray-induced genomic instability and elevated GSH.Sep 26, 2016

Inhibitory potential of Hydroxychavicol on Ehrlich ascites carcinoma model.May 31, 2020

Kolaviron possibly possesses significant antihypertensive effect.May 10, 2021

kombucha consumption may be beneficial to intestinal health.Dec 07, 2022

Licorice has hypocholesterolaemic and antioxidant effects. Nov 01, 2006

Liver injury induced by carbon tetrachloride in mice is prevented by the antioxidant capacity of white tea polyphenols.Mar 13, 2019

Long-term consumption of a myricitrin-supplemented diet may effectively protect against HFD-induced obesity and related metabolic disorders.Oct 31, 2019

Longan flower water extract has antiobesity and hypolipidemic effects.Feb 10, 2010

Lonicera caerulea berry polyphenols extract alleviates exercise fatigue.Dec 31, 2021

Lonicera caerulea L. berry polyphenols might inhibit LPS-induced inflammation by modulating both inflammatory and antioxidant mediators.Jun 27, 2017

Loquat leaves are a potential source of micronutrients and polyphenols with beneficial effects on diabetes and its complications.Oct 04, 2022

Lychee seed polyphenol ameliorates diabetic retinopathy via inhibiting inflammasome/apoptosis and angiogenesis.Oct 31, 2023

Lychee seed polyphenol inhibits Aβ-induced activation of NLRP3 inflammasome.Aug 04, 2020

Malus baccata (Linn.) Borkh polyphenols-loaded nanoparticles ameliorate intestinal health by modulating intestinal function and gut microbiota.Nov 30, 2023

Mango leaves hae antioxidant and antiulcerogenic action.Jan 01, 2009

Mango polyphenolics might be relevant as preventive agents in ulcerative colitis.Apr 05, 2016

Milk thistle sprouts have significant antioxidant value which increases with light exposure. Sep 05, 2005

Moderate consumption of Cabernet Sauvignon attenuates Abeta neuropathology in a mouse model of Alzheimer's disease.Nov 01, 2006

Modulation of Th1/Th2 cytokines and inflammatory mediators by hydroxychavicol in adjuvant induced arthritic tissues.Dec 31, 2009

Muskmelon, watermelon and mango fruit may have an ameliorative effect on atherogenic diet induced dyslipidemia, hypothyroidism and hyperglycemia in rats.Jan 01, 2008

Myricitrin ameliorates cognitive deficits in MCAO cerebral stroke.Jan 31, 2021

Myricitrin ameliorates hyperglycemia, glucose intolerance, hepatic steatosis, and inflammation.Mar 08, 2020

Myricitrin attenuates memory impairment in a rat model of sepsis-associated encephalopathy.Dec 31, 2018

Myricitrin blocks activation of NF-κB and MAPK signaling pathways to protect nigrostriatum neuron in LPS-stimulated mice.Jan 14, 2019

Myricitrin pretreatment ameliorates mouse liver ischemia reperfusion injury.Nov 30, 2020

Myricitrin protects against cisplatin-induced kidney injury by eliminating excessive reactive oxygen species.Dec 31, 2019

Myricitrin regulates proliferation, apoptosis and inflammation of chondrocytes treated with IL-1β.Apr 19, 2020

Natural polyphenols extracted from S. nigra and A. melanocarpa modulate specific and non-specific immune defences in insulin-deficiency diabetes.Mar 31, 2015

Neuroprotective and anti-inflammatory effects of Pinus densiflora bark extract.Jul 28, 2021

Neuroprotective effect of polyphenol extracts from Terminalia chebula against cerebral ischemia-reperfusion injury.Sep 29, 2022

Nutritional antioxidants such as green tea polyphenols and tetrahydrocurcumin may beneficially modify the life span of animals.Oct 01, 2007

Obese rats treated with green tea showed a significant reduction in indicators of obesity such as hyperlipidemia, fat synthesis, body weight, and fat depots.Sep 10, 2015

Oligonol ameliorates liver function and brain function in the 5 × FAD mouse model.Oct 15, 2023

Oligonol may function to suppress MetS and the progression of geriatric diseases in western diet fed mice.Jun 30, 2016

Olive mill wastewater and hydroxytyrosol inhibits atherogenesis in apolipoprotein E-deficient mice.Oct 31, 2023

Onion flesh and onion peel enhance antioxidant status in aged rats.Feb 01, 2007

Oolong tea increases bacterial biodiversity and the abundance of butyrate- and acetate-producing bacteria in high fat diet-induced obesity mice.Feb 21, 2018

Our results reveal Flavin7 (F7) had substantial tumour-suppression effects of 58 % and reduced tumour incidence by 24 % in this breast cancer model.Apr 30, 2015

Peach polyphenols inhibited tumor growth and reduced the risk of metastasis in MDA-MB-435 cells at levels achievable with diet.Mar 18, 2014

Peanut protein-polyphenol aggregate complexation suppresses allergic sensitization to peanut by reducing peanut-specific IgE.Jun 16, 2019

Phloridzin ameliorates type 2 diabetes-induced depression in mice by mitigating oxidative stress and modulating brain-derived neurotrophic factor.May 31, 2021

Phoenix dactylifera and polyphenols ameliorated monosodium glutamate toxicity in the dentate gyrus.Jun 29, 2023

Photoprotective effects of sweet potato leaf polyphenols and caffeic acid against UV-induced skin-damage.Jul 03, 2022

Phyllanthus amarus has radioprotective properties. Jan 01, 2009

Phytochemical profiling of polyphenols and thyroid stimulatory activity of Ficus religiosa leaf extract in 6-propyl-thiouracil-induced hypothyroidism.Sep 14, 2023

Pine need extract is anti-inflammatory and has a protective effect on cholesteorl oxidation. Jan 01, 2008

Plant-derived polyphenols prevent fatty liver disease through by regulating the expressions of miRNA .Jun 30, 2012

Plantain extract has neutralizing properties on snake venom induced toxicity.Apr 08, 2005

Polyherbal formulation PL02 alleviates pain, inflammation, and subchondral bone deterioration in an osteoarthritis.Dec 31, 2022

Polyphenol enrichment of a blueberry preparation by fermentation increases its chemopreventive potential.Dec 31, 2015

Polyphenol extract of Moringa oleifera leaves alleviates colonic inflammation. Dec 31, 2019

Polyphenol-rich açaí seed extract exhibits reno-protective and anti-fibrotic activities.Dec 01, 2022

Polyphenol-rich extract from grape and blueberry attenuates cognitive decline and improves neuronal function in aged mice.Dec 31, 2017

Polyphenol-rich loquat fruit extract prevents fructose-induced nonalcoholic fatty liver disease.Jul 09, 2019

Polyphenolic-rich Cissus quadrangularis extract ameliorates insulin resistance.Dec 31, 2021

Polyphenols and polysaccharides from Morus alba fruit attenuate high-fat diet-induced metabolic syndrome modifying the gut microbiota.Jun 19, 2022

Polyphenols can be promising in combating diabetic neuropathy-associated damaging pathways.Dec 31, 2020

Polyphenols derived from lychee seed suppress amyloid-β-induced neuroinflammation.Jul 19, 2018

Polyphenols from bees wax exhibit hepatoprotective and antioxidative properties. Oct 01, 2007

Polyphenols from Passiflora ligularis regulate inflammatory markers and weight gain.Jun 04, 2021

Polyphenols from Toona sinensis seeds alleviate neuroinflammation in rats with Parkinson's disease.Aug 31, 2019

Polyphenols from Toona sinensiss seeds alleviate neuroinflammation induced by 6-hydroxydopamine.Jun 16, 2020

Polyphenols

View the Evidence:
1003 Abstracts with Polyphenols Research