Niacin

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75 Diseases Researched for Niacin
NameACCKFocus
Metabolic Syndrome X431Locked
Rosacea330Locked
Glaucoma524Locked
DNA damage322Locked
Dyslipidemias422Locked
HDL: Low321Locked
Depression220Locked
Hepatitis A 120Locked
Intima Media Thickening 220Locked
Diabetes Mellitus: Type 2415Locked
Alzheimer's Disease212Locked
Hyperphosphatemia312Locked
Parkinson's Disease212Locked
Chronic Kidney Disease (CKD)211Locked
Hemodialysis211Locked
Migraine Disorders211Locked
Acne110Locked
Aging Skin110Locked
Bipolar Disorder110Locked
Blue Light Toxicity110Locked
Breast Cancer110Locked
Cardiac Mortality 110Locked
Carotid Artery Narrowing110Locked
Cataract110Locked
Cognitive Decline/Dysfunction110Locked
Coronary Artery Disease110Locked
Endothelial Dysfunction110Locked
Erectile Dysfunction110Locked
Fibrinogen: Elevated110Locked
Glioma110Locked
Headache110Locked
Hyperthyroidism110Locked
Metabolic Diseases110Locked
Pellagra110Locked
Periodontitis110Locked
Peripheral Vascular Diseases110Locked
Radiation Induced Illness110Locked
Vitamin B Deficiency110Locked
Xeroderma Pigmentosum110Locked
Inflammation24Locked
Oxidative Stress24Locked
Sepsis24Locked
Arteriosclerosis23Locked
Atherosclerosis12Locked
Brain Inflammation 12Locked
Cardiac Arrest12Locked
Diabetes: Oxidative Stress12Locked
Diarrhea12Locked
Hypercholesterolemia12Locked
Hyperglycemia12Locked
Inflammatory Bowel Diseases12Locked
Kidney Failure12Locked
Kidney Failure: Chronic12Locked
Mercury Poisoning12Locked
Mitochondrial Diseases12Locked
Mitochondrial Dysfunction 12Locked
Muscle Atrophy 12Locked
Myocardial Infarction12Locked
Nerve Injuries12Locked
Neurodegenerative Diseases12Locked
Nonalcoholic fatty liver disease (NAFLD)12Locked
Obesity12Locked
Ovarian Failure12Locked
Peripheral Nerve Diseases12Locked
Pulmonary Fibrosis12Locked
Sitting Sickness12Locked
Ulcerative Colitis12Locked
Apolipoprotein Disorders11Locked
Cancer Metastasis11Locked
Cardiovascular Diseases11Locked
Colon Cancer11Locked
Melanoma11Locked
Multiple Sclerosis11Locked
Skin Cancer: Non-Melanoma11Locked
Tuberculosis11Locked
33 Pharmacological Actions Researched for Niacin
NameACCKFocus
Anti-Inflammatory Agents1042Locked
Neuroprotective Agents627Locked
Prophylactic Agents220Locked
Hypolipidemic314Locked
Cardioprotective212Locked
DNA Repair Up-regulation211Locked
Anticarcinogenic Agents110Locked
Anticholesteremic Agents110Locked
Antidepressive Agents110Locked
Dermatologic Agents110Locked
Gastrointestinal Agents110Locked
Insulin Sensitizers110Locked
Photoprotective110Locked
Antioxidants58Locked
Anti-Apoptotic24Locked
NF-kappaB Inhibitor24Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor24Locked
Angiogenesis Inhibitors12Locked
Antidiarrheals12Locked
Cyclooxygenase 2 Inhibitors12Locked
Gastroprotective12Locked
Hepatoprotective12Locked
Hypoglycemic Agents12Locked
Nitric Oxide Inhibitor12Locked
Nrf2 activation12Locked
Protein Kinase Inhibitors12Locked
Vascular Endothelial Growth Factor Inhibitors12Locked
Anti-Bacterial Agents11Locked
Anti-metastatic11Locked
Antiproliferative 11Locked
Apoptotic11Locked
Chemopreventive11Locked
Remyelination11Locked

View the Evidence:
70 Abstracts with Niacin Research

[+]

A combination of coenzyme Q10, riboflavin and niacin may improve outcome in women with breast cancer undergoing tamoxifen therapy. Oct 01, 2009

Pubmed Data : Planta Med. 2009 Oct;75(13):1415-7. Epub 2009 Jun 16. PMID: 17268082
Article Published Date : Oct 01, 2009
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10, Niacin, Riboflavin (Vitamin B-2)
Diseases : Breast Cancer
Additional Keywords : Drug-Plant-Vitamin Synergies
[+]

A combination of nicotinamide 750 mg, zinc 25 mg, copper 1.5 mg, and folic acid 500 microg, marketed as Nicomide, appears to be an effective oral therapy for the treatment of acne vulgaris and rosacea. Jan 01, 2006

Pubmed Data : Cutis. 2006 Jan;77(1 Suppl):17-28. PMID: 16871775
Article Published Date : Jan 01, 2006
Study Type : Human Study
Additional Links
Substances : Copper, Folic Acid , Vitamin B-3 (Niacin), Zinc
Diseases : Acne, Rosacea
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Association of dietary niacin intake with all-cause and cardiovascular mortality of adult patients with chronic kidney disease.Dec 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Nutr. 2024 ;11:1436836. Epub 2024 Aug 30. PMID: 39279901
Article Published Date : Dec 31, 2023
Study Type : Human Study
Additional Links
Substances : Vitamin B-3 (Niacin)
Diseases : Cardiac Mortality , Chronic Kidney Disease (CKD)
Pharmacological Actions : Cardioprotective
[+]

Associations of dietary vitamin B1, vitamin B2, niacin, vitamin B6, vitamin B12 and folate equivalent intakes with metabolic syndrome.Jan 26, 2020

Pubmed Data : Int J Food Sci Nutr. 2020 Jan 27:1-12. Epub 2020 Jan 27. PMID: 31986943
Article Published Date : Jan 26, 2020
Study Type : Human Study
Additional Links
Substances : Folate, Riboflavin (Vitamin B-2), Thiamine (B-1) , Vitamin B-12, Vitamin B-3 (Niacin), Vitamin B-6
Diseases : Metabolic Diseases, Metabolic Syndrome X
Additional Keywords : Risk Reduction
[+]

B vitamins could be used to improve mood symptoms and mental health quality of life in adults with depression.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : ISRN Psychiatry. 2013 ;2013:621453. Epub 2013 Jan 21. PMID: 23738221
Article Published Date : Dec 31, 2012
Study Type : Human Study
Additional Links
Substances : Riboflavin (Vitamin B-2), Vitamin B-12, Vitamin B-3 (Niacin), Vitamin B-5 (Pantothenic Acid), Vitamin B-6
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
[+]

Complementary and alternative medicine (CAM) in headache of children and adolescents.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Ter. 2020 ;171(5):e393-e398. PMID: 32901780
Article Published Date : Dec 31, 2019
Study Type : Human Study
Additional Links
Substances : Andrographis, Coenzyme Q10, Ginkgo biloba, Magnesium, Melatonin, Riboflavin (Vitamin B-2), Vitamin B-3 (Niacin), Vitamin D
Diseases : Headache
Pharmacological Actions : Prophylactic Agents
[+]

Consumption of foods with high niacin levels may help prevent or delay the onset of dyslipidemia.Nov 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Nutr. 2022 Dec ;41(12):2749-2758. Epub 2022 Oct 28. PMID: 36372046
Article Published Date : Nov 30, 2022
Study Type : Human Study
Additional Links
Substances : Vitamin B-3 (Niacin)
Diseases : Dyslipidemias
Pharmacological Actions : Gastrointestinal Agents
[+]

Dietary niacin may protect against Alzheimer's disease and age related cognitive decline.Jul 31, 2004

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neurol Neurosurg Psychiatry. 2004 Aug ;75(8):1093-9. PMID: 15258207
Article Published Date : Jul 31, 2004
Study Type : Human Study
Additional Links
Substances : Vitamin B-3 (Niacin)
Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Risk Reduction
[+]

Dietary nutrient intake was associated with open-angle glaucoma independent of intraocular pressure.Mar 21, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Mar 22 ;10(4). Epub 2018 Mar 22. PMID: 29565276
Article Published Date : Mar 21, 2018
Study Type : Human Study
Additional Links
Substances : beta-Carotene, Fiber, Riboflavin (Vitamin B-2), Thiamine (B-1) , Vitamin A, Vitamin B-3 (Niacin), Vitamin C
Diseases : Glaucoma
[+]

Elevated consumption of vitamin B6 and niacin, in conjunction with regular vitamin E intake may have the potential to delay or prevent cataract genesis.Dec 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Nutr. 2024 ;11:1406147. Epub 2024 Aug 9. PMID: 39183990
Article Published Date : Dec 31, 2023
Study Type : Human Study
Additional Links
Substances : Vitamin B6, Vitamin B-3 (Niacin), Vitamin E
Diseases : Cataract
Pharmacological Actions : Prophylactic Agents
[+]

Extended-release niacin significantly increases HDL-C and induces atherosclerosis regression in statin treatment. Nov 01, 2006

Pubmed Data : Curr Med Res Opin. 2006 Nov;22(11):2243-50 PMID: 17076985
Article Published Date : Nov 01, 2006
Study Type : Human Study
Additional Links
Substances : Niacin
Diseases : Intima Media Thickening
[+]

High dietary niacin intake is associated with decreased chromosome translocation frequency in airline pilots.Oct 08, 2010

Pubmed Data : Br J Nutr. 2010 Oct 8:1-9. Epub 2010 Oct 8. PMID: 20932352
Article Published Date : Oct 08, 2010
Study Type : Human Study
Additional Links
Substances : Niacin
Diseases : DNA damage, Radiation Induced Illness
Additional Keywords : Radiation Exposure Related to Aviation
[+]

Higher dietary intake of thiamine, riboflavin, nicotinic acid, and folate are associated with a decreased risk of glioma.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Nutr. 2023 ;10:1122540. Epub 2023 Mar 2. PMID: 36937346
Article Published Date : Dec 31, 2022
Study Type : Human Study
Additional Links
Substances : Folate, Riboflavin (Vitamin B-2), Thiamine (B-1) , Vitamin B-3 (Niacin)
Diseases : Glioma
Pharmacological Actions : Anticarcinogenic Agents
Additional Keywords : Risk Factors
[+]

Higher levels of niacin intake were associated with decreased odds of glaucoma.May 31, 2023

Pubmed Data : J Glaucoma. 2023 Jun 1 ;32(6):443-450. Epub 2023 Mar 20. PMID: 36946914
Article Published Date : May 31, 2023
Study Type : Human Study
Additional Links
Substances : Vitamin B-3 (Niacin)
Diseases : Glaucoma
Additional Keywords : Risk Reduction
[+]

Inadequate dietary intake of vitamin B3 was associated with periodontitis.Oct 02, 2019

Pubmed Data : Community Dent Oral Epidemiol. 2019 Oct 3. Epub 2019 Oct 3. PMID: 31583741
Article Published Date : Oct 02, 2019
Study Type : Human Study
Additional Links
Substances : Vitamin B-3 (Niacin)
Diseases : Periodontitis, Vitamin B Deficiency
Additional Keywords : Increased Risk
[+]

Low dose niacin supplementation may be beneficial in Parkinson's disease.Jul 14, 2018

Pubmed Data : J Neuroimmunol. 2018 Jul 15 ;320:76-79. Epub 2018 May 4. PMID: 29759143
Article Published Date : Jul 14, 2018
Study Type : Human Study
Additional Links
Substances : Vitamin B-3 (Niacin)
Diseases : Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Niacin action in the atherogenic mixed dyslipidemia of metabolic syndrome.Mar 28, 2018

Pubmed Data : J Clin Lipidol. 2018 Mar 29. Epub 2018 Mar 29. PMID: 29753732
Article Published Date : Mar 28, 2018
Study Type : Human Study
Additional Links
Substances : Vitamin B-3 (Niacin)
Diseases : Dyslipidemias, Metabolic Syndrome X
Pharmacological Actions : Anti-Inflammatory Agents, Anticholesteremic Agents, Hypolipidemic, Insulin Sensitizers
[+]

Niacin contributes to elevating HDL cholesterol in men and women with coronary heart disease. May 01, 2008

Pubmed Data : Indian Heart J. 2008 May-Jun;60(3):215-22. PMID: 19240310
Article Published Date : May 01, 2008
Study Type : Human Study
Additional Links
Substances : Niacin
Diseases : HDL: Low
[+]

Niacin has potential therapeutic use in patients with xeroderma pigmentosum.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Genet. 2015 Jan ;87(1):56-61. Epub 2013 Dec 20. PMID: 24354460
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Vitamin B-3 (Niacin)
Diseases : DNA damage, Pellagra, Xeroderma Pigmentosum
Pharmacological Actions : DNA Repair Up-regulation
Additional Keywords : Cockayne Syndrome
[+]

Niacin lowers serum phosphate and increases HDL cholesterol in dialysis patients.Nov 01, 2007

Pubmed Data : Clin J Am Soc Nephrol. 2007 Nov;2(6):1249-54. Epub 2007 Oct 3. PMID: 17913971
Article Published Date : Nov 01, 2007
Study Type : Human Study
Additional Links
Substances : Niacin
Diseases : HDL: Low, Hemodialysis, Hyperphosphatemia
[+]

Niacin regresses carotid intimal medial thickness, reduces vascular inflammation and improves endothelial function in patients with metabolic syndrome. Nov 01, 2007

Pubmed Data : Int J Clin Pract. 2007 Nov;61(11):1942-8. PMID: 17935553
Article Published Date : Nov 01, 2007
Study Type : Human Study
Additional Links
Substances : Niacin
Diseases : Carotid Artery Narrowing, Intima Media Thickening , Metabolic Syndrome X
[+]

Niacin supplementation decreases plasma fibrinogen and LDL cholesterol in subjects with peripheral vascular disease. Sep 01, 1998

Pubmed Data : Am J Cardiol. 1998 Sep 1;82(5):697-9, A9. PMID: 9732910
Article Published Date : Sep 01, 1998
Study Type : Human Study
Additional Links
Substances : Niacin
Diseases : Fibrinogen: Elevated, Peripheral Vascular Diseases
[+]

Niacin treatment improves endothelial dysfunction in patients with Coronary Artery Disease. May 01, 2009

Pubmed Data : Atherosclerosis. 2009 May;204(1):216-21. Epub 2008 Aug 12. PMID: 18822413
Article Published Date : May 01, 2009
Study Type : Human Study
Additional Links
Substances : Niacin
Diseases : Coronary Artery Disease, Endothelial Dysfunction
[+]

Niacinamide-containing facial moisturizer improves skin barrier and benefits subjects with rosacea.Aug 01, 2005

Pubmed Data : Cutis. 2005 Aug;76(2):135-41. PMID: 16209160
Article Published Date : Aug 01, 2005
Study Type : Human Study
Additional Links
Substances : Niacin
Diseases : Rosacea
[+]

Nicotinic acid decreases serum thyroid hormone concentrations while maintaining a euthyroid state. Jun 01, 1995

Pubmed Data : Mayo Clin Proc. 1995 Jun;70(6):556-8. PMID: 7776715
Article Published Date : Jun 01, 1995
Study Type : Human Study
Additional Links
Substances : Vitamin B-3 (Niacin)
Diseases : Hyperthyroidism
[+]

Pigmentation effects of blue light irradiation on skin and how to protect against them.Jul 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Cosmet Sci. 2020 Aug ;42(4):399-406. PMID: 32478879
Article Published Date : Jul 31, 2020
Study Type : Human Study
Additional Links
Substances : Algae, Vitamin B-3 (Niacin)
Diseases : Aging Skin, Blue Light Toxicity
Therapeutic Actions : Placebo Effect
Pharmacological Actions : Photoprotective
Anti Therapeutic Actions : Blue Light (400−495 nm)
[+]

Propionyl-L-carnitine, L-arginine and niacin have value in erectile dysfunction. Oct 04, 2011

Pubmed Data : Andrologia. 2011 Oct 4. Epub 2011 Oct 4. PMID: 21966881
Article Published Date : Oct 04, 2011
Study Type : Human Study
Additional Links
Substances : Arginine, Carnitine: propionyl-L-carnitine, Niacin
Diseases : Erectile Dysfunction
[+]

The consumption of adequate amounts of niacin can reduce the risk of diabetes.May 21, 2023

Pubmed Data : Exp Clin Endocrinol Diabetes. 2023 May 22. Epub 2023 May 22. PMID: 36805533
Article Published Date : May 21, 2023
Study Type : Human Study
Additional Links
Substances : Vitamin B-3 (Niacin)
Diseases : Diabetes Mellitus: Type 2
Additional Keywords : Risk Reduction
[+]

Topical application of 1-methylnicotinamide, a vitamin B-3 metabolite, may have therapeutic value in the treatment of rosacea. Nov 01, 2005

Pubmed Data : Clin Exp Dermatol. 2005 Nov;30(6):632-5. PMID: 16197374
Article Published Date : Nov 01, 2005
Study Type : Human Study
Additional Links
Substances : Niacin
Diseases : Rosacea
Pharmacological Actions : Dermatologic Agents
[+]

Tryptophan, Niacin, Calcium, and Caffeine may have therapeutic value in the treatment of migraines. Jan 01, 2001

Pubmed Data : Med Hypotheses. 2001 Jan;56(1):91-4. PMID: 11133261
Article Published Date : Jan 01, 2001
Study Type : Human Study
Additional Links
Substances : Caffeine, Calcium, Niacin, Tryptophan
Diseases : Migraine Disorders
[+]

Tryptophan-nicotinamide may be as effect as imipramine in the treatment of depression. Apr 01, 1979

Pubmed Data : Acta Psychiatr Scand. 1979 Apr;59(4):395-414. PMID: 155389
Article Published Date : Apr 01, 1979
Study Type : Human Study
Additional Links
Substances : Niacin, Tryptophan
Diseases : Bipolar Disorder, Depression
Additional Keywords : Drug: Imipramine, Drug-Plant-Vitamin Synergies, Natural Substances Versus Drugs
[+]

Water soluble vitamins have a therapeutic effect in patients with hepatitis A. Jan 01, 1992

Pubmed Data : Klin Med (Mosk). 1992 Jan;70(1):73-5. PMID: 1608218
Article Published Date : Jan 01, 1992
Study Type : Human Study
Additional Links
Substances : Niacin, Pantothenic Acid (Vitamin B-5), Vitamin B-12, Vitamin B-3 (Niacin), Vitamin B-6, Vitamin C
Diseases : Hepatitis A
[+]

A combination of mitochondrial targeting nutrients may improve skeletal mitochondrial dysfunction and exert hypoglycemic effects, without causing weight gain.Jan 01, 2008

Pubmed Data : PLoS One. 2008;3(6):e2328. Epub 2008 Jun 4. PMID: 18523557
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Substances : Acetyl-l-carnitine, Alpha-Lipoic Acid, Biotin, Niacin
Diseases : Diabetes Mellitus: Type 2, Mitochondrial Diseases, Mitochondrial Dysfunction
[+]

B vitamins had the potential for treatment of neuroinflammation and neuroregeneration.Dec 16, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 Dec 17 ;24(24). Epub 2019 Dec 17. PMID: 31861069
Article Published Date : Dec 16, 2019
Study Type : Animal Study
Additional Links
Substances : Pantothenic Acid (Vitamin B-5), Riboflavin (Vitamin B-2), Thiamine (B-1) , Vitamin B-12, Vitamin B-3 (Niacin), Vitamin B-6
Diseases : Brain Inflammation , Nerve Injuries, Neurodegenerative Diseases, Peripheral Nerve Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Combination therapy of niacin and apocynin attenuates lung injury during sepsis.Apr 30, 2023

Pubmed Data : J Surg Res. 2023 May ;285:51-58. Epub 2023 Jan 12. PMID: 36640610
Article Published Date : Apr 30, 2023
Study Type : Animal Study
Additional Links
Substances : Apocynin, Vitamin B-3 (Niacin)
Diseases : Sepsis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Combination therapy of niacin and selenium attenuated lung injury and improved survival during sepsis. Dec 01, 2015

Pubmed Data : Crit Care Med. 2015 Dec 2. Epub 2015 Dec 2. PMID: 26646455
Article Published Date : Dec 01, 2015
Study Type : Animal Study
Additional Links
Substances : Niacin, Selenium
Diseases : Sepsis
Pharmacological Actions : Antioxidants, Nrf2 activation
Additional Keywords : Natural Substance Synergy
[+]

Dietary niacin supplementation might help in reducing problems associated with diabetes.Aug 31, 2018

Pubmed Data : Biomed Pharmacother. 2018 Sep ;105:1223-1231. Epub 2018 Jun 22. PMID: 30021358
Article Published Date : Aug 31, 2018
Study Type : Animal Study
Additional Links
Substances : Vitamin B-3 (Niacin)
Diseases : Diabetes: Oxidative Stress, Diabetes Mellitus: Type 2, DNA damage, Hyperglycemia
Pharmacological Actions : Antioxidants, Hypoglycemic Agents
[+]

Hericium erinaceus, in combination with natural flavonoid/alkaloid and B3/B8 vitamins, can improve inflammatory burden in Inflammatory bowel diseases.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2023 ;14:1215329. Epub 2023 Jul 3. PMID: 37465689
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Biotin, Lion's Mane (Hericium Erinaceus), Vitamin B-3 (Niacin)
Diseases : Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Niacin alleviates atherosclerosis through restraining the expression of adhesion molecules and inflammatory cytokines secretion in serum.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Sci Monit. 2015 ;21:4081-9. Epub 2015 Dec 29. PMID: 26712802
Article Published Date : Dec 31, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Niacin
Diseases : Atherosclerosis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Niacin ameliorates hepatic steatosis.Dec 19, 2019

Pubmed Data : J Nutr. 2019 Dec 20. Epub 2019 Dec 20. PMID: 31858105
Article Published Date : Dec 19, 2019
Study Type : Animal Study
Additional Links
Substances : Vitamin B-3 (Niacin)
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Hepatoprotective, Hypolipidemic
[+]

Niacin ameloriates symptoms of chronic kidney failure in rats. Jul 01, 2009

Pubmed Data : Am J Physiol Renal Physiol. 2009 Jul;297(1):F106-13. Epub 2009 May 6. PMID: 19420110
Article Published Date : Jul 01, 2009
Study Type : Animal Study
Additional Links
Substances : Niacin
Diseases : Kidney Failure, Kidney Failure: Chronic
[+]

Niacin and selenium attenuate brain injury after cardiac arrest.May 07, 2018

Pubmed Data : Crit Care Med. 2018 May 8. Epub 2018 May 8. PMID: 29742581
Article Published Date : May 07, 2018
Study Type : Animal Study
Additional Links
Substances : Selenium, Vitamin B-3 (Niacin)
Diseases : Cardiac Arrest
Pharmacological Actions : Neuroprotective Agents
[+]

Niacin can reduce leptin in a rabit model of hypercholesterolemia. Jul 01, 2008

Pubmed Data : Cardiovasc Pathol. 2008 Jul-Aug;17(4):219-25. Epub 2008 Apr 1. PMID: 18402819
Article Published Date : Jul 01, 2008
Study Type : Animal Study
Additional Links
Substances : Niacin
Diseases : Arteriosclerosis, Hypercholesterolemia
[+]

Niacin could effectively attenuate the over expression of nitric oxide synthase in the rat lung induced by silica particles. May 01, 2004

Pubmed Data : Zhonghua Yu Fang Yi Xue Za Zhi. 2004 May;38(3):186-9. PMID: 15182488
Article Published Date : May 01, 2004
Study Type : Animal Study
Additional Links
Substances : Niacin
Diseases : Pulmonary Fibrosis
Pharmacological Actions : Nitric Oxide Inhibitor
[+]

Niacin may have an important function in treating premature Ovarian FailureDec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Physiol Biochem. 2018 ;50(6):2060-2070. Epub 2018 Nov 9. PMID: 30415247
Article Published Date : Dec 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitamin B-3 (Niacin)
Diseases : Ovarian Failure, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic
[+]

Niacin prevents mitochondrial oxidative stress caused by sub-chronic exposure to methylmercury.Sep 06, 2018

Pubmed Data : Drug Chem Toxicol. 2018 Sep 7:1-7. Epub 2018 Sep 7. PMID: 30192646
Article Published Date : Sep 06, 2018
Study Type : Animal Study
Additional Links
Substances : Vitamin B-3 (Niacin)
Diseases : Mercury Poisoning, Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

Niacin promotes cardiac healing after myocardial infarction.Feb 28, 2017

Pubmed Data : J Pharmacol Exp Ther. 2017 Mar ;360(3):435-444. Epub 2017 Jan 5. PMID: 28057839
Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Substances : Vitamin B-3 (Niacin)
Diseases : Inflammation, Myocardial Infarction
Pharmacological Actions : Cardioprotective
[+]

Niacin supplementation attenuates the regression of three-dimensional capillary architecture in unloaded female rat skeletal muscle.Mar 31, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Physiol Rep. 2024 Apr ;12(8):e16019. PMID: 38627220
Article Published Date : Mar 31, 2024
Study Type : Animal Study
Additional Links
Substances : Vitamin B-3 (Niacin)
Diseases : Muscle Atrophy , Sitting Sickness
Additional Keywords : Physical Inactivity
[+]

Niacin supplementation increased AQPs and ZO-1 expression to reduce diarrhea and intestinal damage.Jul 27, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2022 Jul 28 ;23(15). Epub 2022 Jul 28. PMID: 35955466
Article Published Date : Jul 27, 2022
Study Type : Animal Study
Additional Links
Substances : Vitamin B-3 (Niacin)
Diseases : Diarrhea
Pharmacological Actions : Antidiarrheals, Gastroprotective
[+]

Niacin was effective against iodoacetamide-induced colitis through ameliorating pathologic angiogenesis and inflammatory changes.Aug 01, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Aug 2 ;7(1):7139. Epub 2017 Aug 2. PMID: 28769047
Article Published Date : Aug 01, 2017
Study Type : Animal Study
Additional Links
Substances : Vitamin B-3 (Niacin)
Diseases : Ulcerative Colitis
Pharmacological Actions : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Vascular Endothelial Growth Factor Inhibitors
[+]

Niacin, an innovative protein kinase-C-dependent endoplasmic reticulum stress reticence in murine Parkinson's disease.Aug 14, 2024

Pubmed Data : Life Sci. 2024 Aug 15 ;351:122865. Epub 2024 Jun 22. PMID: 38914304
Article Published Date : Aug 14, 2024
Study Type : Animal Study
Additional Links
Substances : Niacin
Diseases : Parkinson's Disease
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents, Protein Kinase Inhibitors
[+]

Nicotinamide restores cognition in Alzheimer's disease transgenic mice.Nov 05, 2008

Pubmed Data : J Neurosci. 2008 Nov 5;28(45):11500-10. PMID: 18987186
Article Published Date : Nov 05, 2008
Study Type : Animal Study
Additional Links
Substances : Niacin
Diseases : Alzheimer's Disease
[+]

Supplementation with B vitamins could reduce body weight gain and plasma levels of lipids by improving energy metabolism-related enzyme activities.Jan 31, 2018

Pubmed Data : Curr Med Sci. 2018 Feb ;38(1):174-183. Epub 2018 Mar 15. PMID: 30074168
Article Published Date : Jan 31, 2018
Study Type : Animal Study
Additional Links
Substances : Riboflavin (Vitamin B-2), Thiamine (B-1) , Vitamin B-3 (Niacin)
Diseases : Obesity
Pharmacological Actions : Hypolipidemic
Additional Keywords : Anti-Obesity Agents
[+]

Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice.Feb 16, 2017

Pubmed Data : Science. 2017 Feb 17 ;355(6326):756-760. PMID: 28209901
Article Published Date : Feb 16, 2017
Study Type : Animal Study
Additional Links
Substances : Vitamin B-3 (Niacin)
Diseases : Glaucoma
Additional Keywords : Risk Reduction
[+]

Are anti-inflammatory foods associated with a protective effect for cutaneous melanoma? Aug 31, 2020

Pubmed Data : Eur J Cancer Prev. 2020 Sep ;29(5):466-469. PMID: 32740173
Article Published Date : Aug 31, 2020
Study Type : Review
Additional Links
Substances : beta-Carotene, Folic Acid , Lutein, Lycopene, Omega-3 Fatty Acids, Vitamin A, Vitamin B-3 (Niacin), Vitamin C, Vitamin D, Zeaxanthin
Diseases : Melanoma
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Citicoline/coenzyme Q10/vitamin B3 fixed combination exerts synergistic protective effects on neuronal cells exposed to oxidative stress.Jul 19, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2022 Jul 20 ;14(14). Epub 2022 Jul 20. PMID: 35889920
Article Published Date : Jul 19, 2022
Study Type : In Vitro Study
Additional Links
Substances : Coenzyme Q10, Vitamin B-3 (Niacin)
Diseases : Brain: Oxidative Stress, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Natural Substance Synergy
[+]

Niacin and omega-3 fatty acids may correct non-HDL lipoprotein and apolipoprotein B abnormalities.Jan 01, 2004

Pubmed Data : Am J Chin Med. 2004;32(2):175-83. PMID: 19545870
Article Published Date : Jan 01, 2004
Study Type : Commentary
Additional Links
Substances : Niacin, Omega-3 Fatty Acids
Diseases : Apolipoprotein Disorders, Diabetes Mellitus: Type 2, Dyslipidemias, Metabolic Syndrome X
[+]

Niacin and related compounds may have utility for the treatment of both hyperphosphatemia and dyslipidemia in CKD patients to prevent CVD.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2015 ;61 Suppl:S173-5. PMID: 26598845
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Substances : Niacin
Diseases : Chronic Kidney Disease (CKD), Dyslipidemias, Hyperphosphatemia
[+]

NIacin may be an inexpensive and effective phosphate reducer in dialysis patients with hyperphosphatemia. Nov 27, 2008

Pubmed Data : Int Urol Nephrol. 2008 Nov 27. Epub 2008 Nov 27. PMID: 19037739
Article Published Date : Nov 27, 2008
Study Type : Commentary
Additional Links
Substances : Niacin
Diseases : Hemodialysis, Hyperphosphatemia
[+]

Niacin may have therapeutic value in the prevention of migraine headache.Jun 01, 2003

Pubmed Data : Mayo Clin Proc. 2003 Jun;78(6):770-1. PMID: 12934790
Article Published Date : Jun 01, 2003
Study Type : Commentary
Additional Links
Substances : Niacin
Diseases : Migraine Disorders
[+]

Niacin may raise HDL cholesterol. Feb 01, 2010

Pubmed Data : Pediatr Allergy Immunol. 2010 Feb;21(1 Pt 1):60-6. Epub 2010 Jan 14. PMID: 18316796
Article Published Date : Feb 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Niacin
Diseases : HDL: Low
[+]

Niacin supplemenation may reduce risk for arthersclerotic disease by protecting endothelial function. Mar 01, 2009

Pubmed Data : Basic Clin Pharmacol Toxicol. 2009 Mar;104(3):206-10. Epub 2009 Jan 21. PMID: 19159436
Article Published Date : Mar 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Niacin
Diseases : Arteriosclerosis
[+]

Niacin: another look at an underutilized lipid-lowering medication.Aug 31, 2012

Pubmed Data : Nat Rev Endocrinol. 2012 Sep ;8(9):517-28. Epub 2012 Feb 21. PMID: 22349076
Article Published Date : Aug 31, 2012
Study Type : Review
Additional Links
Substances : Niacin
Diseases : Cardiovascular Diseases
Additional Keywords : Medication Reduction
[+]

nicotinamide reduces the incidence of actinic keratoses and non-melanoma skin cancers in high-risk individuals.Jul 04, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Photodermatol Photoimmunol Photomed. 2017 Jul 5. Epub 2017 Jul 5. PMID: 28681504
Article Published Date : Jul 04, 2017
Study Type : Review
Additional Links
Substances : Nicotinamide, Vitamin B-3 (Niacin)
Diseases : Skin Cancer: Non-Melanoma
Pharmacological Actions : Chemopreventive, DNA Repair Up-regulation
Additional Keywords : Risk Reduction
[+]

Opposing effects of low versus high concentrations of water soluble vitamins/dietary ingredients vitamin C and niacin on colon cancer stem cells.Sep 30, 2017

Pubmed Data : Cell Biol Int. 2017 Oct ;41(10):1127-1145. Epub 2017 Aug 24. PMID: 28755485
Article Published Date : Sep 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Vitamin B-3 (Niacin), Vitamin C
Diseases : Colon Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Cancer Stem Cells, Dose Response
[+]

Strategies to reduce oxidative stress in glaucoma patients.Jan 04, 2017

Pubmed Data : Curr Neuropharmacol. 2017 07 5. Epub 2017 Jul 5. PMID: 28677495
Article Published Date : Jan 04, 2017
Study Type : Review
Additional Links
Substances : Coenzyme Q10, Ginkgo biloba, Green Tea, Melatonin, Omega-3 Fatty Acids, Omega-6 Fatty Acids, Vitamin B-3 (Niacin), Vitamin C, Vitamin E
Diseases : Glaucoma
Pharmacological Actions : Antioxidants
[+]

The anti-inflammatory and re-myelinating attributes of vitamin B complex members are promisingSep 05, 2017

Pubmed Data : Med Chem. 2017 Sep 6. Epub 2017 Sep 6. PMID: 28875857
Article Published Date : Sep 05, 2017
Study Type : Review
Additional Links
Substances : Riboflavin (Vitamin B-2), Vitamin B-12, Vitamin B-3 (Niacin), Vitamin B-5 (Pantothenic Acid), Vitamin B-6
Diseases : Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Remyelination
Additional Keywords : Demyelinating Diseases
[+]

The present study indicates for the first time the anti-invasive activities of niacin and trigonelline against cancer cells.Feb 28, 2005

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Biotechnol Biochem. 2005 Mar ;69(3):653-8. PMID: 15785001
Article Published Date : Feb 28, 2005
Study Type : In Vitro Study
Additional Links
Substances : Fenugreek, Vitamin B-3 (Niacin)
Diseases : Cancer Metastasis
Pharmacological Actions : Anti-metastatic
[+]

Treatment of glaucoma with natural products and their mechanism of action: an update.Jan 25, 2022

Pubmed Data : Nutrients. 2022 Jan 26 ;14(3). Epub 2022 Jan 26. PMID: 35276895
Article Published Date : Jan 25, 2022
Study Type : Review
Additional Links
Substances : Anthocyanins, Baicalein, Barberry, Caffeine, Cannabis, Coenzyme Q10, Curcumin, Ginkgo biloba, Ginsenosides, Hesperidin, Resveratrol, Saffron, Tripterygium wilfordii, Vitamin B-3 (Niacin), Vitamin D
Diseases : Glaucoma
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Vitamins can prove to be useful agents capable of modifying the life cycle and biology of M. tuberculosis.Sep 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mycobacteriol. 2017 Oct-Dec;6(4):328-332. PMID: 29171444
Article Published Date : Sep 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Vitamin B-3 (Niacin), Vitamin B-5 (Pantothenic Acid), Vitamin B-6, Vitamin C, Vitamin D, Vitamin E, Vitamin K
Diseases : Tuberculosis
Pharmacological Actions : Anti-Bacterial Agents
Anti Therapeutic Actions : Air Travel

Copyright: lculig / 123RF Stock Photo

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