Lion's Mane (Hericium Erinaceus)

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85 Diseases Researched for Lion's Mane (Hericium Erinaceus)
NameACCKFocus
Alzheimer's Disease1533Locked
Cognitive Decline/Dysfunction729Locked
Depression922Locked
Oxidative Stress1115Locked
Dementia314Locked
Obesity313Locked
Neurodegenerative Diseases812Locked
Parkinson's Disease712Locked
Sleep Disorders212Locked
Anxiety Disorders211Locked
Gastric Ulcer610Locked
Memory Disorders510Locked
Overweight 110Locked
Stress110Locked
Anxiety59Locked
Cancers: All79Locked
Alcohol Toxicity 48Locked
Inflammatory Bowel Diseases48Locked
Aging47Locked
Brain Inflammation 37Locked
Colitis47Locked
Inflammation67Locked
Lipopolysaccharide-Induced Toxicity46Locked
Ulcerative Colitis36Locked
Aging: Brain 24Locked
Chemotherapy-Induced Toxicity: Cyclophosphamide24Locked
Peripheral Nerve Diseases24Locked
Brain Ischemia13Locked
Breast Cancer23Locked
Colon Cancer23Locked
Colorectal Cancer23Locked
Helicobacter Pylori Infection23Locked
Hydrogen Peroxide Induced Toxicity33Locked
Aflatoxicosis12Locked
Amyloid toxicity 12Locked
Amyloid β peptide toxicity12Locked
Ataxia: Cerebellar12Locked
Brain Injury: Traumatic12Locked
Brain: Oxidative Stress22Locked
Cerebral Ischemia12Locked
Chronic Pain12Locked
Diabetes Mellitus: Type 212Locked
Diabetic Complications12Locked
Diabetic Neuropathy12Locked
Epilepsy12Locked
High Fat Diet12Locked
High Sugar Diet12Locked
Hyperglycemia22Locked
Immune Disorders: Low Immune Function12Locked
Learning disorders12Locked
Lipid Metabolism: Abnormalities12Locked
Low Immune Function: Natural Killer Cells12Locked
Lung Cancer22Locked
Neurologic Disorders22Locked
Neuropathic Pain12Locked
Nonalcoholic fatty liver disease (NAFLD)12Locked
Optic Neuropathy12Locked
Osteoarthritis: Knee12Locked
Traumatic Brain Injury12Locked
Tumors12Locked
Wound Healing12Locked
Adrenal Gland Diseases11Locked
Adrenal Gland: Enhanced Apoptosis11Locked
Allergies11Locked
Bladder Cancer11Locked
Coronavirus Infection11Locked
Demyelinating Diseases11Locked
Dengue11Locked
Dysbiosis11Locked
Esophageal Cancer11Locked
Gastric Cancer11Locked
Glioma11Locked
Gram-Negative Bacterial Infections11Locked
Gram-Positive Bacterial Infections11Locked
Infant Acute Monocytic Leukemia11Locked
Leukemia: Monocytic11Locked
Liver Cancer11Locked
Mycotoxin Toxicity11Locked
Neurological Conditions11Locked
Phthalate Toxicity 11Locked
Pseudomonas aeruginosa11Locked
Salmonella Infections11Locked
Staphylococcus aureus infection11Locked
Thrombosis11Locked
Ultraviolet Radiation Induced Damage11Locked
61 Pharmacological Actions Researched for Lion's Mane (Hericium Erinaceus)
NameACCKFocus
Neuroprotective Agents46103Locked
Anti-Inflammatory Agents3152Locked
Antioxidants3447Locked
Antidepressive Agents821Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor1121Locked
Anti-Anxiety Agents619Locked
Immunomodulatory1117Locked
Brain-derived neurotrophic factor modulator416Locked
Interleukin-1 beta downregulation816Locked
Anti-Apoptotic813Locked
Interleukin-6 Downregulation712Locked
Neuritogenic912Locked
Apoptotic911Locked
Gastroprotective711Locked
Anxiolytic110Locked
Gastrointestinal Agents610Locked
Cyclooxygenase 2 Inhibitors48Locked
NF-kappaB Inhibitor58Locked
Nrf2 activation57Locked
Anti-Ulcer Agents35Locked
Chemotherapeutic35Locked
Hepatoprotective35Locked
Analgesics24Locked
Anti-Bacterial Agents34Locked
Antiproliferative 44Locked
Hypoglycemic Agents34Locked
Malondialdehyde Down-regulation24Locked
Anti-Angiogenic23Locked
Chemopreventive33Locked
Heme oxygenase-1 up-regulation23Locked
5-Lipoxygenase Inhibitor12Locked
Alpha-glucosidase inhibitor 22Locked
Anticarcinogenic Agents22Locked
Antineoplastic Agents12Locked
Antinoceceptive 12Locked
Antioxidant Effects12Locked
Cell cycle arrest22Locked
Chemoprotective Agents12Locked
Interleukin-10 upregulation12Locked
Neurogenesis12Locked
Regenerative12Locked
Vascular Endothelial Growth Factor Inhibitors12Locked
Alpha-amylase inhibitor11Locked
Anti-Allergic Agents11Locked
Antihypertensive Agents11Locked
Antimicrobial11Locked
Antimutagenic Agents11Locked
Antiviral Agents11Locked
Cardioprotective11Locked
Caspase-3 Activation11Locked
Caspase-9 Activation11Locked
Chemosensitizer11Locked
Hypolipidemic11Locked
Interleukin-8 downregulation11Locked
Matrix metalloproteinase-9 (MMP-9) inhibitor11Locked
Nitric Oxide Enhancer11Locked
Photoprotective11Locked
Platelet Aggregation Inhibitors11Locked
Platelet aggregation inhibitor: collagen-induced aggregation11Locked
Prostaglandin PGE2 downregulation11Locked
Reactive Oxygen Species (ROS) attenuation11Locked
Related Topics

Lion's Mane (Hericium Erinaceus) is a Sub of the following Topic

View the Evidence:
136 Abstracts with Lion's Mane (Hericium Erinaceus) Research

[+]

Hericium erinaceus improves mood and sleep disorders in patients affected by overweight or obesity.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2019 ;2019:7861297. Epub 2019 Apr 18. PMID: 31118969
Article Published Date : Dec 31, 2018
Study Type : Human Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Obesity, Overweight , Sleep Disorders
Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents, Brain-derived neurotrophic factor modulator
[+]

Hericium erinaceus intake results in a reduction of depression and anxiety in mice by 4 weeks. Aug 01, 2010

Pubmed Data : Biomed Res. 2010 Aug ;31(4):231-7. PMID: 20834180
Article Published Date : Aug 01, 2010
Study Type : Human Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Anxiety Disorders, Depression
Pharmacological Actions : Anxiolytic
[+]

Improvement of cognitive functions by oral intake of Hericium erinaceus Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res. 2019 ;40(4):125-131. PMID: 31413233
Article Published Date : Dec 31, 2018
Study Type : Human Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Cognitive Decline/Dysfunction, Dementia
Pharmacological Actions : Neuroprotective Agents
[+]

Lion's mane improves mild cognitive impairment in human subjects. Mar 01, 2009

Pubmed Data : Phytother Res. 2009 Mar ;23(3):367-72. PMID: 18844328
Article Published Date : Mar 01, 2009
Study Type : Human Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Cognitive Decline/Dysfunction
[+]

Prevention of early Alzheimer's disease by Erinacine A-enriched Hericium erinaceus mycelia.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Aging Neurosci. 2020 ;12:155. Epub 2020 Jun 3. PMID: 32581767
Article Published Date : Dec 31, 2019
Study Type : Human Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

The acute and chronic effects of Lion's mane mushroom supplementation on cognitive function, stress and mood in young adults.Nov 19, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2023 Nov 20 ;15(22). Epub 2023 Nov 20. PMID: 38004235
Article Published Date : Nov 19, 2023
Study Type : Human Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Stress
Pharmacological Actions : Neuroprotective Agents
[+]

Erinacine A attenuates glutamate transporter 1 downregulation and protects against ischemic brain injury.Sep 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Life Sci. 2022 Oct 1 ;306:120833. Epub 2022 Jul 23. PMID: 35882273
Article Published Date : Sep 30, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Brain Ischemia
Pharmacological Actions : Neuroprotective Agents
[+]

Erinacine A prevents lipopolysaccharide-mediated glial cell activation to protect dopaminergic neurons against inflammatory factor-induced cell death.Jan 11, 2022

Pubmed Data : Int J Mol Sci. 2022 Jan 12 ;23(2). Epub 2022 Jan 12. PMID: 35054997
Article Published Date : Jan 11, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity, Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

A fungal protein from H. erinaceus could be used as a drug or functional food ingredient for immunotherapy.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2017 ;8:666. Epub 2017 Jun 12. PMID: 28713364
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Cancers: All, Inflammatory Bowel Diseases
Pharmacological Actions : Chemotherapeutic, Immunomodulatory
[+]

A polysaccharide fraction is the active component of the H. erinaceus mycelium culture, which protects against gastric ulcers.Dec 31, 2014

Pubmed Data : Int J Med Mushrooms. 2015 ;17(11):1055-60. PMID: 26853960
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents
Additional Keywords : Plant Extracts
[+]

Aflatoxin B1 Toxicity in Zebrafish Larva ( Danio rerio): Protective Role of Hericium erinaceus.Oct 07, 2021

Pubmed Data : Toxins (Basel). 2021 Oct 8 ;13(10). Epub 2021 Oct 8. PMID: 34679002
Article Published Date : Oct 07, 2021
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Aflatoxicosis, Oxidative Stress
Pharmacological Actions : Antioxidants
Problem Substances : Aflatoxin
[+]

Ameliorating effects of Hericium erinaceus polysaccharides on intestinal barrier injury in immunocompromised mice induced by cyclophosphamide.Mar 19, 2023

Pubmed Data : Food Funct. 2023 Mar 20 ;14(6):2921-2932. Epub 2023 Mar 20. PMID: 36892225
Article Published Date : Mar 19, 2023
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation
Additional Keywords : Polysaccharides
[+]

Benefits of erinacines from different cultivate Formulas on cognitive deficits and anxiety-like behaviour.Aug 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Trop Life Sci Res. 2023 Sep ;34(3):165-183. Epub 2023 Sep 30. PMID: 37860101
Article Published Date : Aug 31, 2023
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Anxiety, Cognitive Decline/Dysfunction
Pharmacological Actions : Anti-Anxiety Agents, Neuroprotective Agents
[+]

Boosting memory by an ergothioneine-rich Hericium erinaceus primordium extract.Jan 27, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biology (Basel). 2023 Jan 28 ;12(2). Epub 2023 Jan 28. PMID: 36829475
Article Published Date : Jan 27, 2023
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Memory Disorders
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Interleukin-6 Downregulation, Neuroprotective Agents
[+]

Chemical constituents from Hericium erinaceus promote neuronal survival and potentiate neurite outgrowth.Jul 29, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2017 Jul 30 ;18(8). Epub 2017 Jul 30. PMID: 28758954
Article Published Date : Jul 29, 2017
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Memory Disorders
Pharmacological Actions : Neuritogenic
[+]

Effects of Hericium erinaceus mycelium extracts on the functional activity of purinoceptors and neuropathic pain.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2020 ;2020:2890194. Epub 2020 May 13. PMID: 32508945
Article Published Date : Dec 31, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Brain Inflammation , Neuropathic Pain
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Interleukin-6 Downregulation, Neuroprotective Agents
[+]

Erinacine A and S reduce Alzheimer’s disease pathology via reducing amyloid deposition and promoting neurogenesis.Feb 16, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2018 Feb 17 ;19(2). Epub 2018 Feb 17. PMID: 29463001
Article Published Date : Feb 16, 2018
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Alzheimer's Disease
Pharmacological Actions : Neurogenesis, Neuroprotective Agents
[+]

erinacine A-enriched HE mycelium could be an attractive agent for the treatment of depressive disorders.Jan 23, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2018 Jan 24 ;19(2). Epub 2018 Jan 24. PMID: 29364170
Article Published Date : Jan 23, 2018
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Depression
Pharmacological Actions : Antidepressive Agents, Brain-derived neurotrophic factor modulator
[+]

Erinacine A-enriched Hericium erinaceus mycelia promotes longevity in Drosophila melanogaster and aged mice.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2019 ;14(5):e0217226. Epub 2019 May 17. PMID: 31100095
Article Published Date : Dec 31, 2018
Study Type : Animal Study, Insect Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Aging, Neurodegenerative Diseases
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Erinacine A-enriched Hericium erinaceus mycelium ameliorates Alzheimer’s disease-related pathologies.Jun 26, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Biomed Sci. 2016 Jun 27 ;23(1):49. Epub 2016 Jun 27. PMID: 27350344
Article Published Date : Jun 26, 2016
Study Type : Transgenic Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Alzheimer's Disease, Dementia
Pharmacological Actions : Neuroprotective Agents
[+]

Erinacine A-enriched Hericium erinaceus mycelium delays progression of age-related cognitive decline.Oct 18, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2021 Oct 19 ;13(10). Epub 2021 Oct 19. PMID: 34684662
Article Published Date : Oct 18, 2021
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Aging: Brain , Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
[+]

Extracts of Hericium erinaceus can be applied as a protective agent in the treatment of IBDs.Dec 31, 2015

Pubmed Data : Int J Med Mushrooms. 2016 ;18(3):227-34. PMID: 27481156
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Colitis, Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Fermented H erinaceus juice may be used as one of the food-based health-promoting supplement to manage diabetes mellitus along with medication.Dec 31, 2017

Pubmed Data : J Evid Based Integr Med. 2018 Jan-Dec;23:2515690X18765699. PMID: 29619846
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Fermented Foods and Beverages, Lactobacillus fermentum, Lion's Mane (Hericium Erinaceus)
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
[+]

Gastroprotective activity of polysaccharide from the fruiting body of Hericium erinaceus against acetic acid-induced gastric ulcer.Jun 14, 2022

Pubmed Data : Int J Biol Macromol. 2022 Jun 15 ;210:455-464. Epub 2022 Apr 26. PMID: 35483513
Article Published Date : Jun 14, 2022
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents, Gastroprotective
Additional Keywords : Polysaccharides
[+]

H. erinaceus extracts could promote the growth of beneficial gut bacteria and improve the host immunity in vivo IBD model.Oct 16, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 Oct 17 ;8(49):85838-85857. Epub 2017 Sep 6. PMID: 29156761
Article Published Date : Oct 16, 2017
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

H. erinaceus induces a boost effect onto neuronal functions also in nonpathological conditions.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2017 ;2017:3864340. Epub 2017 Jan 1. PMID: 28115973
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
[+]

H. erinaceus SG-02 could be used as a functional food and natural drug for the prevention of diabetes and its complications.Sep 06, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Sep 7 ;7(1):10847. Epub 2017 Sep 7. PMID: 28883631
Article Published Date : Sep 06, 2017
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Diabetic Complications
Pharmacological Actions : Antioxidants, Hypoglycemic Agents
[+]

Hericium erinaceus administration can exert anxiolytic and antidepressant-like effects.Jan 31, 2018

Pubmed Data : J Med Food. 2018 Feb ;21(2):174-180. Epub 2017 Nov 1. PMID: 29091526
Article Published Date : Jan 31, 2018
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Anxiety, Depression
Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents
[+]

Hericium erinaceus and Coriolus versicolor modulate molecular and biochemical changes after traumatic brain injury.Jun 01, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2021 Jun 2 ;10(6). Epub 2021 Jun 2. PMID: 34199629
Article Published Date : Jun 01, 2021
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus), Turkey Tail Mushroom
Diseases : Brain Injury: Traumatic, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Hericium erinaceus could promote the antitumor efficacy of 5-Fu by improving the microbiota composition, the immune inflammatory response, and homeostasis.May 26, 2020

Pubmed Data : J Food Sci. 2020 May 27. Epub 2020 May 27. PMID: 32460371
Article Published Date : May 26, 2020
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Cancers: All
Pharmacological Actions : Anti-Inflammatory Agents, Chemotherapeutic, Immunomodulatory
Additional Keywords : Chemothapeutic Synergy: 5-flourouracil
[+]

Hericium erinaceus improves recognition memory and induces hippocampal and cerebellar neurogenesis in frail mice during aging.Mar 26, 2019

Pubmed Data : Nutrients. 2019 Mar 27 ;11(4). Epub 2019 Mar 27. PMID: 30934760
Article Published Date : Mar 26, 2019
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Aging: Brain , Memory Disorders
Pharmacological Actions : Neuroprotective Agents
[+]

Hericium erinaceus may provide neuroprotective candidates for treating or preventing neurodegenerative diseases.Oct 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2016 Nov 1 ;17(11). Epub 2016 Nov 1. PMID: 27809277
Article Published Date : Oct 31, 2016
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Alzheimer's Disease, Dementia, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Dose Response
[+]

Hericium erinaceus mycelium ameliorate anxiety induced by continuous sleep disturbance in vivo.Dec 04, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Med Ther. 2021 Dec 5 ;21(1):295. Epub 2021 Dec 5. PMID: 34865649
Article Published Date : Dec 04, 2021
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Anxiety, Sleep Disorders
Pharmacological Actions : Anti-Anxiety Agents
[+]

Hericium erinaceus mycelium ameliorates in vivo progression of osteoarthritis.Jun 22, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2022 Jun 23 ;14(13). Epub 2022 Jun 23. PMID: 35807786
Article Published Date : Jun 22, 2022
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Osteoarthritis: Knee
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation
[+]

Hericium erinaceus mycelium may be a potential health-promoting supplement for minimizing the progression of aging and obesity-induced neurodegeneration.Apr 30, 2019

Pubmed Data : J Med Food. 2019 May ;22(5):469-478. PMID: 31084539
Article Published Date : Apr 30, 2019
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Aging, Brain Inflammation , High Fat Diet, High Sugar Diet, Obesity
Pharmacological Actions : Anti-Inflammatory Agents, Neuritogenic, Neuroprotective Agents
[+]

Hericium erinaceus mycelium-derived polysaccharide alleviates ulcerative colitis.Nov 27, 2022

Pubmed Data : Mol Nutr Food Res. 2022 Nov 28:e2200450. Epub 2022 Nov 28. PMID: 36443636
Article Published Date : Nov 27, 2022
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents
Additional Keywords : Polysaccharides
[+]

Hericium erinaceus polysaccharide possess gastroprotective activity.Apr 14, 2018

Pubmed Data : Carbohydr Polym. 2018 Apr 15 ;186:100-109. Epub 2018 Jan 2. PMID: 29455967
Article Published Date : Apr 14, 2018
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Alcohol Toxicity , Gastric Ulcer
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Gastroprotective, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Polysaccharides
[+]

Hericium erinaceus polysaccharide significantly improved the immune and antioxidant functions.Dec 08, 2022

Pubmed Data : Biosci Biotechnol Biochem. 2022 Dec 9. Epub 2022 Dec 9. PMID: 36494196
Article Published Date : Dec 08, 2022
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Pharmacological Actions : Anti-Apoptotic, Antioxidant Effects, Immunomodulatory
Additional Keywords : Polysaccharides
[+]

Hericium erinaceus polysaccharides ameliorate nonalcoholic fatty liver disease.Jun 30, 2024

Pubmed Data : Int J Biol Macromol. 2024 Jul ;273(Pt 1):132735. Epub 2024 Jun 1. PMID: 38825293
Article Published Date : Jun 30, 2024
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Gastrointestinal Agents
Additional Keywords : Gut-liver axis, Polysaccharides
[+]

Hericium erinaceus promotes anti-inflammatory effects and regulation of metabolites in an animal model of cerebellar ataxia.Mar 22, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2023 Mar 23 ;24(7). Epub 2023 Mar 23. PMID: 37047062
Article Published Date : Mar 22, 2023
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Ataxia: Cerebellar
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Hericium erinaceus supplementation could restrain the hepatic damage caused by acute alcohol exposure.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2015 ;2015:418023. Epub 2015 Apr 16. PMID: 25960751
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Alcohol Toxicity
Pharmacological Actions : Hepatoprotective
Additional Keywords : Plant Extracts
[+]

Hericium erinaceus treatment along with the antioxidant activity could be the probable way by which it had alleviated diabetic neuropathy.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2015 ;2015:595480. Epub 2015 Apr 16. PMID: 25960754
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Diabetic Neuropathy
Pharmacological Actions : Analgesics, Antioxidants
Problem Substances : Alloxan
[+]

Hericium erinaceus, in combination with natural flavonoid/alkaloid and B3/B8 vitamins, can improve inflammatory burden in Inflammatory bowel diseases.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2023 ;14:1215329. Epub 2023 Jul 3. PMID: 37465689
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Biotin, Lion's Mane (Hericium Erinaceus), Vitamin B-3 (Niacin)
Diseases : Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Improvement of extraction from Hericium erinaceus on the gut-brain axis in AD-like mice.Jan 14, 2022

Pubmed Data : Brain Res. 2022 10 15 ;1793:148038. Epub 2022 Aug 4. PMID: 35934088
Article Published Date : Jan 14, 2022
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Alzheimer's Disease
Pharmacological Actions : Gastrointestinal Agents, Neuroprotective Agents
Additional Keywords : Gut-brain Axis
[+]

In vitro and in vivo inhibition of helicobacter pylori by ethanolic extracts of lion's mane medicinal mushroom.Dec 31, 2018

Pubmed Data : Int J Med Mushrooms. 2019 ;21(1):1-11. PMID: 30806251
Article Published Date : Dec 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Helicobacter Pylori Infection
Pharmacological Actions : Anti-Bacterial Agents
[+]

Induction of apoptosis by erinacine A in human colorectal cancer cells.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2019 ;10:1174. Epub 2019 Oct 15. PMID: 31680958
Article Published Date : Dec 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Colorectal Cancer
Pharmacological Actions : Apoptotic
[+]

Lion's Mane extract is capable of promoting peripheral nerve regeneration after injury in rats.Aug 25, 2014

Pubmed Data : Chin J Integr Med. 2014 Aug 26. Epub 2014 Aug 26. PMID: 25159861
Article Published Date : Aug 25, 2014
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Peripheral Nerve Diseases
Pharmacological Actions : Regenerative
Additional Keywords : Nerve Regeneration, Plant Extracts
[+]

Lion's mane has antitumor effects in tumor-bearing mice.Sep 28, 2011

Pubmed Data : J Agric Food Chem. 2011 Sep 28 ;59(18):9861-9. Epub 2011 Aug 25. PMID: 21846141
Article Published Date : Sep 28, 2011
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Colon Cancer, Low Immune Function: Natural Killer Cells, Tumors
Pharmacological Actions : 5-Lipoxygenase Inhibitor, Anti-Angiogenic, Antineoplastic Agents, Cyclooxygenase 2 Inhibitors, Vascular Endothelial Growth Factor Inhibitors
[+]

Lion's mane improves lipid metabolism in mice fed a high-fat diet.Jan 01, 2010

Pubmed Data : Biosci Biotechnol Biochem. 2010 ;74(7):1447-51. Epub 2010 Jul 7. PMID: 20622452
Article Published Date : Jan 01, 2010
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Lipid Metabolism: Abnormalities
[+]

Lion's mane prevented impairments of spatial short-term and visual recognition memory induced by amyloid β(25-35) peptide. Feb 01, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res. 2011 Feb ;32(1):67-72. PMID: 21383512
Article Published Date : Feb 01, 2011
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Amyloid toxicity , Amyloid β peptide toxicity, Learning disorders, Memory Disorders, Neurodegenerative Diseases
Pharmacological Actions : Neuroprotective Agents
[+]

Lion's mane stimulates immune function. Jan 01, 2005

Pubmed Data : J Herb Pharmacother. 2005;5(1):17-26. PMID: 7950232
Article Published Date : Jan 01, 2005
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Immune Disorders: Low Immune Function
Pharmacological Actions : Immunomodulatory
[+]

Liver and brain protective effect of sulfated polysaccharides from residue of Lion's mane medicinal mushroom.Dec 31, 2020

Pubmed Data : Int J Med Mushrooms. 2021 ;23(5):55-65. PMID: 34347995
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Aging
Pharmacological Actions : Hepatoprotective, Neuroprotective Agents
Additional Keywords : Polysaccharides
[+]

Low weight polysaccharide of Hericium erinaceus ameliorates colitis.Jan 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2023 Feb 1 ;15(3). Epub 2023 Feb 1. PMID: 36771444
Article Published Date : Jan 31, 2023
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Colitis, Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Modulating effects of Hericium erinaceus polysaccharides on the immune response by regulating gut microbiota in cyclophosphamide.Dec 21, 2022

Pubmed Data : J Sci Food Agric. 2022 Dec 22. Epub 2022 Dec 22. PMID: 36546454
Article Published Date : Dec 21, 2022
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions : Chemoprotective Agents, Gastrointestinal Agents, Immunomodulatory
Additional Keywords : Polysaccharides
[+]

Mushroom extracts and compounds with suppressive action on breast cancer.May 31, 2020

Pubmed Data : Appl Microbiol Biotechnol. 2020 Jun ;104(11):4675-4703. Epub 2020 Apr 9. PMID: 32274562
Article Published Date : May 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus), Medicinal Mushrooms, Phellinus Linteus, Shitake Mushroom
Diseases : Breast Cancer
Pharmacological Actions : Apoptotic
[+]

Neurogenesis-dependent antidepressant-like activity of Hericium erinaceus in an animal model of depression.Dec 06, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Chin Med. 2021 Dec 7 ;16(1):132. Epub 2021 Dec 7. PMID: 34876186
Article Published Date : Dec 06, 2021
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Depression
Pharmacological Actions : Antidepressive Agents, Brain-derived neurotrophic factor modulator
[+]

Neuroprotective effects of dehydroepiandrosterone and Hericium erinaceus in scopolamine-induced Alzheimer's diseases-like symptoms.Jul 10, 2024

Pubmed Data : Cell Biochem Biophys. 2024 Jul 11. Epub 2024 Jul 11. PMID: 38990419
Article Published Date : Jul 10, 2024
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Neuroprotective effects of erinacine A on an experimental model of traumatic optic neuropathy.Jan 11, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2023 Jan 12 ;24(2). Epub 2023 Jan 12. PMID: 36675019
Article Published Date : Jan 11, 2023
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Optic Neuropathy
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Neuroprotective Agents, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Neuroprotective metabolites of Hericium erinaceus promote neuro-healthy aging.Jun 14, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2021 Jun 15 ;22(12). Epub 2021 Jun 15. PMID: 34203691
Article Published Date : Jun 14, 2021
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Cognitive Decline/Dysfunction, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

PHEB alleviated the oxidative stress in brains of AD mice.Oct 21, 2021

Pubmed Data : Int J Biol Macromol. 2021 Oct 22 ;193(Pt A):358-369. Epub 2021 Oct 22. PMID: 34688684
Article Published Date : Oct 21, 2021
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Polysaccharide of Hericium erinaceus attenuates colitis.Dec 31, 2017

Pubmed Data : J Nutr Biochem. 2018 07 ;57:67-76. Epub 2018 Mar 16. PMID: 29677563
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Colitis, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Polysaccharides
[+]

Polysaccharides from an edible mushroom Hericium erinaceus, alleviate ulcerative colitisApr 30, 2024

Pubmed Data : Int J Biol Macromol. 2024 May ;267(Pt 1):131251. Epub 2024 Mar 30. PMID: 38556226
Article Published Date : Apr 30, 2024
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Oxidative Stress, Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Polysaccharides
[+]

Post-Treatment with Erinacine A attenuates neurotoxicity in MPTP model of Parkinson's disease.Feb 03, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2020 Feb 4 ;9(2). Epub 2020 Feb 4. PMID: 32033220
Article Published Date : Feb 03, 2020
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Potential antidepressant effects of a dietary supplement from the chlorella and lion's mane mushroom complex.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Nutr. 2022 ;9:977287. Epub 2022 Sep 2. PMID: 36118772
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Chlorella (Algae), Lion's Mane (Hericium Erinaceus)
Diseases : Depression
Pharmacological Actions : Antidepressive Agents, Brain-derived neurotrophic factor modulator
[+]

Pre-protective effect of polysaccharides purified from Hericium erinaceus against ethanol-induced gastric mucosal injury.May 21, 2020

Pubmed Data : Int J Biol Macromol. 2020 May 22. Epub 2020 May 22. PMID: 32450327
Article Published Date : May 21, 2020
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Alcohol Toxicity , Gastric Ulcer
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Gastroprotective, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Polysaccharides
[+]

Redox modulation of cellular stress response and lipoxin A4 expression by Hericium Erinaceus in rat brain: relevance to Alzheimer's disease pathogenesis.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Immun Ageing. 2016 ;13:23. Epub 2016 Jul 9. PMID: 27398086
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Alzheimer's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Regenerative activity of Hericium erinaceus on axonal injury model using in vitro laser microdissection technique.Feb 28, 2019

Pubmed Data : Neurol Res. 2019 Mar ;41(3):265-274. Epub 2018 Dec 20. PMID: 30570422
Article Published Date : Feb 28, 2019
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Peripheral Nerve Diseases
Pharmacological Actions : Neuritogenic, Neuroprotective Agents
Additional Keywords : Nerve Regeneration, Phytotherapy, Plant Extracts
[+]

Structural characterization of enzymatic modification of Hericium erinaceus polysaccharide and its immune-enhancement activity.Nov 05, 2020

Pubmed Data : Int J Biol Macromol. 2020 Nov 6. Epub 2020 Nov 6. PMID: 33166554
Article Published Date : Nov 05, 2020
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Pharmacological Actions : Immunomodulatory
Additional Keywords : Polysaccharides
[+]

Structural characterization of two Hericium erinaceus polysaccharides and their protective effects on the alcohol-induced gastric mucosal injury.Apr 30, 2022

Pubmed Data : Food Chem. 2022 May 1 ;375:131896. Epub 2021 Dec 20. PMID: 34954576
Article Published Date : Apr 30, 2022
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Alcohol Toxicity
Pharmacological Actions : Gastroprotective
Additional Keywords : Polysaccharides
[+]

The cerebral protective effect of novel erinacines from Hericium erinaceus mycelium on in vivo mild traumatic brain injury.Mar 18, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2024 Mar 19 ;13(3). Epub 2024 Mar 19. PMID: 38539904
Article Published Date : Mar 18, 2024
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Traumatic Brain Injury
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Nrf2 activation
[+]

These findings highlight the potential application of Hericium erinaceus for preventing neuronal death after seizures.Feb 15, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Feb 16 ;20(4). Epub 2019 Feb 16. PMID: 30781501
Article Published Date : Feb 15, 2019
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Epilepsy
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

These findings provide additional support for the anxiolytic effects of H. erinaceus.Jul 14, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Behav Sci (Basel). 2022 Jul 15 ;12(7). Epub 2022 Jul 15. PMID: 35877305
Article Published Date : Jul 14, 2022
Study Type : Transgenic Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Anxiety
Pharmacological Actions : Anti-Anxiety Agents
[+]

These results suggest that H. erinaceus has preventive and therapeutic potentials in managing memory deficits.Jun 11, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Fungi (Basel). 2021 Jun 12 ;7(6). Epub 2021 Jun 12. PMID: 34204787
Article Published Date : Jun 11, 2021
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Alzheimer's Disease, Memory Disorders
Pharmacological Actions : Neuroprotective Agents
[+]

This study demonstrates novel characteristics of H. erinaceus in reducing nociceptive behaviour.Dec 31, 2016

Pubmed Data : Int J Med Mushrooms. 2017 ;19(6):499-507. PMID: 29199560
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Chronic Pain
Pharmacological Actions : Antinoceceptive
[+]

This work suggests that a synergistic effect of the H. erinaceus mycelium and garlic extract.Jan 31, 2015

Pubmed Data : Arch Physiol Biochem. 2015 Feb ;121(1):19-25. Epub 2014 Oct 30. PMID: 25354984
Article Published Date : Jan 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Garlic, Lion's Mane (Hericium Erinaceus)
Diseases : Cerebral Ischemia
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Natural Substance Synergy, Plant Extracts
[+]

Wounds dressed with HEFB [lion's mane] significantly enhanced the acceleration of wound healing enclosure in rats.Jan 01, 2011

Pubmed Data : Int J Med Mushrooms. 2011 ;13(1):33-9. PMID: 22135902
Article Published Date : Jan 01, 2011
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Wound Healing
[+]

"Inhibitory effect of hericenone B from Hericium erinaceus on collagen-induced platelet aggregation."Dec 01, 2010

Pubmed Data : Phytomedicine. 2010 Dec 1 ;17(14):1082-5. Epub 2010 Jul 16. PMID: 20637576
Article Published Date : Dec 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Hericenone B, Lion's Mane (Hericium Erinaceus)
Diseases : Thrombosis
Pharmacological Actions : Platelet aggregation inhibitor: collagen-induced aggregation, Platelet Aggregation Inhibitors
[+]

A novel Hericium erinaceus polysaccharide prevents H2O2-induced oxidative damage in GES-1 cells.Nov 19, 2019

Pubmed Data : Int J Biol Macromol. 2019 Nov 20. Epub 2019 Nov 20. PMID: 31759012
Article Published Date : Nov 19, 2019
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Hydrogen Peroxide Induced Toxicity, Oxidative Stress
Pharmacological Actions : Antioxidants, Gastroprotective
[+]

A novel oligosaccharide isolated from Hericium erinaceus and its protection against LPS-induced Caco-2 cells.Feb 29, 2020

Pubmed Data : J Food Biochem. 2020 Mar ;44(3):e13135. Epub 2020 Jan 20. PMID: 31960464
Article Published Date : Feb 29, 2020
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus), Oligosaccharides
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

A novel polysaccharide from Hericium erinaceus: Preparation, structural characteristics, thermal stabilities, and antioxidant activities in vitro.Dec 31, 2020

Pubmed Data : J Food Biochem. 2021 09 ;45(9):e13871. Epub 2021 Aug 17. PMID: 34402085
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
Additional Keywords : Polysaccharides
[+]

A polysaccharide from Lion's mane enhances nerve growth and reduces cell death in adrenal cells. Sep 01, 2002

Pubmed Data : Cytotechnology. 2002 Sep ;39(3):155-62. PMID: 19003308
Article Published Date : Sep 01, 2002
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Adrenal Gland: Enhanced Apoptosis, Adrenal Gland Diseases
Pharmacological Actions : Anti-Apoptotic, Neuritogenic
[+]

A review of the effects of natural compounds, medicinal plants, and mushrooms on the gut microbiota in colitis and cancer.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2020 ;11:744. Epub 2020 May 15. PMID: 32499711
Article Published Date : Dec 31, 2019
Study Type : Review
Additional Links
Substances : Curcumin, Frankincense, Licorice, Lion's Mane (Hericium Erinaceus), Medicinal Mushrooms, Reishi Mushroom
Diseases : Bladder Cancer, Breast Cancer, Cancers: All, Colitis, Dysbiosis, Esophageal Cancer, Lung Cancer
Pharmacological Actions : Anticarcinogenic Agents, Apoptotic, Chemopreventive, Gastrointestinal Agents
[+]

A unique polysaccharide purified from Hericium erinaceus mycelium prevents oxidative stress induced by H2O2 in human gastric mucosa.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2017 ;12(7):e0181546. Epub 2017 Jul 24. PMID: 28742114
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Hydrogen Peroxide Induced Toxicity, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Antioxidants
[+]

A water extract from spent mushroom substrate of Hericium erinaceus suppresses bacterial wilt disease in Tomatoes. Aug 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mycobiology. 2015 Sep ;43(3):311-8. Epub 2015 Sep 30. PMID: 26539048
Article Published Date : Aug 31, 2015
Study Type : Plant Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Additional Keywords : Growing Your Own Food, Plant Extracts
[+]

Anti-aging and neuroprotective properties of Grifola frondosa and Hericium erinaceus extracts.Oct 17, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2022 Oct 18 ;14(20). Epub 2022 Oct 18. PMID: 36297052
Article Published Date : Oct 17, 2022
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus), Maitake Mushroom
Diseases : Aging
Pharmacological Actions : Neuroprotective Agents
[+]

Antibiofilm activity and bioactive phenolic compounds of ethanol extract from the Hericium erinaceus basidiome.Mar 31, 2022

Pubmed Data : J Adv Pharm Technol Res. 2022 Apr-Jun;13(2):111-116. Epub 2022 Apr 7. PMID: 35464662
Article Published Date : Mar 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Pseudomonas aeruginosa, Salmonella Infections, Staphylococcus aureus infection
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation
[+]

Antitumor, anti-inflammatory and antiallergic effects of Agaricus blazei mushroom extract and the related medicinal Basidiomycetes mushrooms.May 07, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 May 8 ;12(5). Epub 2020 May 8. PMID: 32397163
Article Published Date : May 07, 2020
Study Type : Review
Additional Links
Substances : Agaricus Blazei, Lion's Mane (Hericium Erinaceus), Maitake Mushroom
Diseases : Allergies, Cancers: All, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Allergic Agents, Anti-Inflammatory Agents, Antioxidants, Chemopreventive
[+]

Aqueous extracts of Pleurotus ostreatus and Hericium erinaceus protect against ultraviolet A-induced damage in human dermal fibroblasts.Dec 31, 2021

Pubmed Data : Int J Med Mushrooms. 2022 ;24(2):63-74. PMID: 35446523
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus), Oyster Mushroom
Diseases : Ultraviolet Radiation Induced Damage
Pharmacological Actions : Antioxidants, Photoprotective
[+]

Bioactive components isolated from Hericium erinaceus have anti-helicobacter pylori activity.May 12, 2016

Pubmed Data : J Ethnopharmacol. 2016 May 13 ;183:54-8. Epub 2015 Sep 11. PMID: 26364939
Article Published Date : May 12, 2016
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Gastric Ulcer, Helicobacter Pylori Infection
Pharmacological Actions : Anti-Bacterial Agents
[+]

Can medicinal mushrooms have prophylactic or therapeutic effect against COVID‐19 and its pneumonic superinfection and complicating inflammation?Jul 12, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Scand J Immunol. 2020 Jul 13:e12937. Epub 2020 Jul 13. PMID: 32657436
Article Published Date : Jul 12, 2020
Study Type : Review
Additional Links
Substances : Agaricus Blazei, Lion's Mane (Hericium Erinaceus), Maitake Mushroom
Diseases : Coronavirus Infection
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Chemical constituents from Hericium erinaceus have ability to stimulate NGF-mediated neurite outgrowth on PC12 cells.Nov 14, 2015

Pubmed Data : Bioorg Med Chem Lett. 2015 Nov 15 ;25(22):5078-82. Epub 2015 Oct 16. PMID: 26481911
Article Published Date : Nov 14, 2015
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Pharmacological Actions : Neuritogenic
[+]

Edible mushrooms as a potential component of dietary interventions for major depressive disorder.May 19, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Foods. 2022 May 20 ;11(10). Epub 2022 May 20. PMID: 35627059
Article Published Date : May 19, 2022
Study Type : Review
Additional Links
Substances : Cordyceps Militaris, Lion's Mane (Hericium Erinaceus), Reishi Mushroom
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
[+]

Erinacerin O and Erinacerin P are novel compounds from Hericium erinaceus and Erinacerin P could be a potential novel glioma inhibitor.Aug 02, 2020

Pubmed Data : Anticancer Agents Med Chem. 2020 Aug 3. Epub 2020 Aug 3. PMID: 32753025
Article Published Date : Aug 02, 2020
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Glioma
Pharmacological Actions : Apoptotic
[+]

Erinacine S from Hericium erinaceus mycelium promotes neuronal regeneration by inducing neurosteroids accumulation.Mar 14, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Food Drug Anal. 2023 Mar 15 ;31(1):32-54. Epub 2023 Mar 15. PMID: 37224554
Article Published Date : Mar 14, 2023
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Neurodegenerative Diseases
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Nerve Regeneration
[+]

Evaluation of in vitro antioxidant and antihyperglycemic activities of extracts from the Lion's mane medicinal mushroom.Dec 31, 2020

Pubmed Data : Int J Med Mushrooms. 2021 ;23(3):55-66. PMID: 33822499
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Hyperglycemia
Pharmacological Actions : Alpha-amylase inhibitor, Alpha-glucosidase inhibitor , Antioxidants, Hypoglycemic Agents
[+]

Fruiting body polysaccharides of Hericium erinaceus induce apoptosis in human colorectal cancer cells.Jul 21, 2020

Pubmed Data : Food Funct. 2020 Jul 22 ;11(7):6128-6138. PMID: 32573644
Article Published Date : Jul 21, 2020
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Colorectal Cancer
Pharmacological Actions : Apoptotic
Additional Keywords : Polysaccharides
[+]

H. erinaceus a polysaccharide was effective in preventing gastric cancer progression.Dec 31, 2016

Pubmed Data : Int J Med Mushrooms. 2017 ;19(12):1053-1060. PMID: 29431066
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Gastric Cancer, Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents, Apoptotic, Cell cycle arrest, Chemopreventive, Gastroprotective
Additional Keywords : Polysaccharides
[+]

H. erinaceus exerts anti-inflammatory effects on macrophages and ameliorates adipose tissue inflammation associated with obesity.Dec 31, 2014

Pubmed Data : Int J Med Mushrooms. 2015 ;17(7):609-18. PMID: 26559695
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Inflammation, Obesity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

H. erinaceus may be considered as a potent antiangiogenesis candidate to treat diseases with impaired inflammation and cancer.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2016 ;2016:8257238. Epub 2015 Dec 28. PMID: 26823953
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Cancers: All, Inflammation
Pharmacological Actions : Anti-Angiogenic, Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Matrix metalloproteinase-9 (MMP-9) inhibitor, NF-kappaB Inhibitor, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Hericium erinaceus ethanol extract and ergosterol exert anti-inflammatory activities by neutralizing lipopolysaccharide-induced pro-inflammatory cytokine production.Dec 24, 2022

Pubmed Data : Biochem Biophys Res Commun. 2022 Dec 25 ;636(Pt 2):1-9. Epub 2022 Oct 29. PMID: 36335857
Article Published Date : Dec 24, 2022
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation
[+]

Hericium erinaceus extracts maybe a potential neuroprotective and anti-inflammatory agents in neuron-glia environment.Jul 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2019 Aug 1 ;8(8). Epub 2019 Aug 1. PMID: 31374912
Article Published Date : Jul 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Brain: Oxidative Stress, Hydrogen Peroxide Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents, Nrf2 activation
[+]

Hericium erinaceus has protective effects on behavioral alteration and histological modification associated with Alzheimer's disease.Oct 21, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2021 Oct 22 ;10(11). Epub 2021 Oct 22. PMID: 34829535
Article Published Date : Oct 21, 2021
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Alzheimer's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Hericium erinaceus has therapeutic potential and may facilitate memory enhancement in patients with Alzheimer's disease.Jul 23, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cells. 2022 Jul 24 ;11(15). Epub 2022 Jul 24. PMID: 35892581
Article Published Date : Jul 23, 2022
Study Type : Review
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Hericium erinaceus in neurodegenerative diseases.May 09, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Fungi (Basel). 2023 May 10 ;9(5). Epub 2023 May 10. PMID: 37233262
Article Published Date : May 09, 2023
Study Type : Review
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Neurodegenerative Diseases
Pharmacological Actions : Neuroprotective Agents
[+]

Hericium erinaceus polysaccharide could be explored as potential antioxidant agents for deoxynivalenol-induced intestinal mucosa injury.Nov 19, 2019

Pubmed Data : Int J Biol Macromol. 2019 Nov 20. Epub 2019 Nov 20. PMID: 31759000
Article Published Date : Nov 19, 2019
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Mycotoxin Toxicity
Pharmacological Actions : Antioxidants, Gastroprotective
Additional Keywords : Polysaccharides
Problem Substances : Mycotoxin
[+]

Hericium erinaceus polysaccharides exhibit antioxidant and neuroprotective effects on Aβ-induced neurotoxicity in neurons.Jun 06, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2016 Jun 7 ;16:170. Epub 2016 Jun 7. PMID: 27266872
Article Published Date : Jun 06, 2016
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
Additional Keywords : Polysaccharides
[+]

Hericium Erinaceus prevents DEHP-induced mitochondrial dysfunction and apoptosis in PC12 cells.Mar 19, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2020 Mar 20 ;21(6). Epub 2020 Mar 20. PMID: 32244920
Article Published Date : Mar 19, 2020
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Phthalate Toxicity
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents, Nrf2 activation
Problem Substances : Phthalates
[+]

Identification and α-glucosidase inhibitory activity of meroterpenoids from Hericium erinaceus.. Apr 30, 2020

Pubmed Data : Planta Med. 2020 May ;86(8):571-578. Epub 2020 Apr 21. PMID: 32325508
Article Published Date : Apr 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Hyperglycemia
Pharmacological Actions : Alpha-glucosidase inhibitor , Hypoglycemic Agents
[+]

Immunomodulatory effects of Hericium erinaceus derived polysaccharides are mediated by intestinal immunology.Mar 21, 2017

Pubmed Data : Food Funct. 2017 Mar 22 ;8(3):1020-1027. PMID: 28266682
Article Published Date : Mar 21, 2017
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Pharmacological Actions : Immunomodulatory
[+]

Immunomodulatory effects of hydroxyethylated Hericium erinaceus polysaccharide on macrophages.Jul 17, 2017

Pubmed Data : Int J Biol Macromol. 2017 Jul 18. Epub 2017 Jul 18. PMID: 28729219
Article Published Date : Jul 17, 2017
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Pharmacological Actions : Immunomodulatory
Additional Keywords : Polysaccharides
[+]

Lion's main enhances doxorubicin-induced apoptosis in human hepatocellular carcinoma cells.Nov 28, 2010

Pubmed Data : Cancer Lett. 2010 Nov 28 ;297(2):144-54. PMID: 20554107
Article Published Date : Nov 28, 2010
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Liver Cancer
Pharmacological Actions : Apoptotic, Chemosensitizer
Additional Keywords : Drug: Doxorubicin
[+]

Lion's Mane (Hericium erinaceus) contains a compound, Erinacine Q, which stimulates nerve growth factor. Mar 01, 2002

Pubmed Data : Biosci Biotechnol Biochem. 2002 Mar;66(3):571-5. PMID: 12005051
Article Published Date : Mar 01, 2002
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Neuritogenic
[+]

Lion's Mane (Hericium Erinaceus), Reishi (Ganoderma) and Schizophyllum commune mushrooms have antioxidant properties. Jan 01, 2012

Pubmed Data : Evid Based Complement Alternat Med. 2012 ;2012:464238. Epub 2011 Jun 18. PMID: 21716693
Article Published Date : Jan 01, 2012
Study Type : Plant Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus), Reishi Mushroom, Schizophyllum commune
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

Lion's mane contains active compounds that stimulate Neural Growth Factor synthesis.Jul 01, 2007

Pubmed Data : Colorectal Dis. 2007 Jul;9(6):549-52. PMID: 18758067
Article Published Date : Jul 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Neurologic Disorders
Pharmacological Actions : Neuritogenic
[+]

Lion's mane contains compounds with antimutagenicity.May 01, 2001

Pubmed Data : Kaohsiung J Med Sci. 2001 May;17(5):230-8. PMID: 11517861
Article Published Date : May 01, 2001
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Pharmacological Actions : Antimutagenic Agents
[+]

Lion's mane induces programmed cell death in monocytic leukemia cells. Jun 01, 2011

Pubmed Data : Food Funct. 2011 Jun ;2(6):348-56. Epub 2011 Jun 8. PMID: 21779573
Article Published Date : Jun 01, 2011
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Infant Acute Monocytic Leukemia, Leukemia: Monocytic
Pharmacological Actions : Antiproliferative , Apoptotic, Caspase-3 Activation, Caspase-9 Activation
[+]

Lion's mane stimulates nerve myelination.Jan 01, 2003

Pubmed Data : Fiziol Zh. 2003;49(1):38-45. PMID: 12675022
Article Published Date : Jan 01, 2003
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Demyelinating Diseases, Neurologic Disorders
Pharmacological Actions : Neuritogenic
[+]

Lion's mane suppresses LPS-induced pro-inflammation gene activation in macrophages.Nov 29, 2011

Pubmed Data : Immunopharmacol Immunotoxicol. 2011 Nov 29. Epub 2011 Nov 29. PMID: 22126451
Article Published Date : Nov 29, 2011
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Enhancer, Prostaglandin PGE2 downregulation, Reactive Oxygen Species (ROS) attenuation
[+]

Medicinal mushrooms stimulate neurite outgrowth in dissociated cells of brain, spinal cord, and retina.Dec 31, 2014

Pubmed Data : Int J Med Mushrooms. 2015 ;17(11):1047-54. PMID: 26853959
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus), Medicinal Mushrooms
Diseases : Alzheimer's Disease, Parkinson's Disease
Pharmacological Actions : Neuritogenic
Additional Keywords : Plant Extracts
[+]

Neuroprotective effects of Hericium erinaceus against high-dose corticosterone-induced oxidative stress in PC-12 cells.Nov 10, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Med Ther. 2020 Nov 11 ;20(1):340. Epub 2020 Nov 11. PMID: 33176761
Article Published Date : Nov 10, 2020
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Brain: Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Neuroprotective herbs for the management of Alzheimer's disease. Apr 07, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomolecules. 2021 Apr 8 ;11(4). Epub 2021 Apr 8. PMID: 33917843
Article Published Date : Apr 07, 2021
Study Type : Review
Additional Links
Substances : Ashwagandha, Bacopa, Cat's Claw, Ginkgo biloba, Gotu Kola, Lion's Mane (Hericium Erinaceus), Saffron, Triphala, Turmeric
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Neurotrophic and neuroprotective effects of Hericium erinaceus.Nov 02, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2023 Nov 3 ;24(21). Epub 2023 Nov 3. PMID: 37958943
Article Published Date : Nov 02, 2023
Study Type : Review
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Neurodegenerative Diseases
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Peptides obtained from edible mushrooms: Hericium erinaceus offers the ability to scavenge free radicals and induce apoptosis in lung cancer cells.May 19, 2020

Pubmed Data : Food Funct. 2020 May 20. Epub 2020 May 20. PMID: 32432266
Article Published Date : May 19, 2020
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Lung Cancer
Pharmacological Actions : Antioxidants, Antiproliferative , Apoptotic
[+]

Polysaccharide from Hericium erinaceus fruiting bodies induces arrest of cell cycle at S-phage in colon cancer cells.Apr 24, 2020

Pubmed Data : Int J Biol Macromol. 2020 Apr 25 ;157:288-295. Epub 2020 Apr 25. PMID: 32339580
Article Published Date : Apr 24, 2020
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Colon Cancer
Pharmacological Actions : Antiproliferative , Cell cycle arrest
Additional Keywords : Polysaccharides
[+]

Polysaccharides from Hericium erinaceus fruiting bodies: structural characterization, immunomodulatory activity and mechanism.Sep 08, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2022 Sep 9 ;14(18). Epub 2022 Sep 9. PMID: 36145096
Article Published Date : Sep 08, 2022
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Pharmacological Actions : Immunomodulatory
Additional Keywords : Polysaccharides
[+]

Potential antidepressant effects of Scutellaria baicalensis, Hericium erinaceus and Rhodiola rosea.Mar 11, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2020 Mar 12 ;9(3). Epub 2020 Mar 12. PMID: 32178272
Article Published Date : Mar 11, 2020
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus), rhodiola, Skullcap: Chinese
Diseases : Anxiety, Depression
Pharmacological Actions : Anti-Anxiety Agents, Anti-Inflammatory Agents, Antidepressive Agents, Antioxidants, Neuroprotective Agents
[+]

Prospecting medicinal properties of Lion's mane mushroom.Jun 23, 2021

Pubmed Data : J Food Biochem. 2021 Jun 24:e13833. Epub 2021 Jun 24. PMID: 34169530
Article Published Date : Jun 23, 2021
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Gram-Negative Bacterial Infections, Gram-Positive Bacterial Infections, Oxidative Stress
Pharmacological Actions : Antimicrobial, Antioxidants, Antiproliferative
[+]

Reishi and Lion's Mane mushroom powder can be used for the fortification of semolina pasta.Mar 16, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2023 Mar 17 ;12(3). Epub 2023 Mar 17. PMID: 36978986
Article Published Date : Mar 16, 2023
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus), Reishi Mushroom
Diseases : Cancers: All
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

The effects of twenty-one nutrients and phytonutrients on cognitive function: A narrative review.Aug 25, 2021

Pubmed Data : J Clin Transl Res. 2021 Aug 26 ;7(4):575-620. Epub 2021 Aug 4. PMID: 34541370
Article Published Date : Aug 25, 2021
Study Type : Review
Additional Links
Substances : Aloe Vera, Ashwagandha, Bacopa, Lion's Mane (Hericium Erinaceus), NAC (N-acetyl-L-cysteine), Omega-3 Fatty Acids, Rosemary, Saffron, Tart Cherry, Turmeric, Vitamin D, Vitamin E
Diseases : Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
[+]

The reported health-promoting properties of the mushroom fruit bodies, mycelia, and bioactive pure compounds in lion's mane.Aug 04, 2015

Pubmed Data : J Agric Food Chem. 2015 Aug 5. Epub 2015 Aug 5. PMID: 26244378
Article Published Date : Aug 04, 2015
Study Type : Review
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Anxiety Disorders, Depression, Neurological Conditions
Pharmacological Actions : Anticarcinogenic Agents, Antihypertensive Agents, Cardioprotective, Hepatoprotective, Hypolipidemic, Neuroprotective Agents
Additional Keywords : Metabolites
[+]

The use of Hericium erinaceus and Trametes versicolor extracts in supportive treatment in oncology.Feb 28, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Pharm. 2021 Mar 1 ;71(1):1-16. PMID: 32697746
Article Published Date : Feb 28, 2021
Study Type : Review
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Cancers: All
Pharmacological Actions : Chemotherapeutic, Immunomodulatory
[+]

Therapeutic applications of mushrooms and their biomolecules along with a glimpse of in silico approach in neurodegenerative diseases.Apr 30, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2021 May ;137:111377. Epub 2021 Feb 15. PMID: 33601145
Article Published Date : Apr 30, 2021
Study Type : Review
Additional Links
Substances : Lion's Mane (Hericium Erinaceus), Maitake Mushroom, Medicinal Mushrooms
Diseases : Alzheimer's Disease, Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Therapeutic potential of Hericium erinaceus for depressive disorders. Dec 24, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Dec 25 ;21(1). Epub 2019 Dec 25. PMID: 31881712
Article Published Date : Dec 24, 2019
Study Type : Review
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Depression
Pharmacological Actions : Antidepressive Agents
[+]

These findings demonstrated the potential of mushroom extracts as anti-dengue therapeutic agents with less toxic effects.Sep 17, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2019 Sep 18 ;19(1):260. Epub 2019 Sep 18. PMID: 31533688
Article Published Date : Sep 17, 2019
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus), Medicinal Mushrooms, Reishi Mushroom
Diseases : Dengue
Pharmacological Actions : Antiviral Agents
Additional Keywords : Plant Extracts
[+]

These results suggest that HEP-W and HEP-A may be potential gut microbial manipulators to promote gut health.Oct 19, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Polymers (Basel). 2023 Oct 20 ;15(20). Epub 2023 Oct 20. PMID: 37896408
Article Published Date : Oct 19, 2023
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Gastrointestinal Agents
Additional Keywords : Polysaccharides
[+]

These results suggested that Hericium erinaceus could be used as a potential immunoregulatory agent in functional foods.Jan 23, 2018

Pubmed Data : Food Funct. 2018 Jan 24 ;9(1):294-306. PMID: 29168863
Article Published Date : Jan 23, 2018
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Pharmacological Actions : Immunomodulatory

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