Kaempferol

Name	AC	CK
Oxidative Stress	13	29
Inflammation	15	21
Cancers: All	12	14
Diabetes Mellitus: Type 2	7	12
Breast Cancer	10	11
Cognitive Decline/Dysfunction	2	11
Aging: Brain	1	10
All-Cause Mortality	1	10
Cardiac Mortality	1	10
Coronavirus Infection	8	8
Lipopolysaccharide-Induced Toxicity	5	8
Liver Cancer	7	7
Nonalcoholic fatty liver disease (NAFLD)	4	7
Alcoholic Liver Disease	3	6
Insulin Resistance	3	6
Osteoporosis	3	6
Breast Cancer: Triple Negative	4	5
DNA damage	1	5
Obesity	4	5
Sepsis	3	5
Vitiligo	1	5
Cerebral Ischemia	2	4
Chemotherapy-Induced Toxicity: Doxorubicin	2	4
Colitis	2	4
Colorectal Cancer	4	4
Coronavirus Disease (Covid-19)	4	4
Diabetes Mellitus: Type 1	2	4
Diabetic Nephropathy	2	4
Diabetic Neuropathy	2	4
Diabetic Retinopathy	2	4
Klebsiella Infections	3	4
Myocardial Ischemia	3	4
Osteoarthritis	2	4
Staphylococcus aureus infection	4	4
Alcohol Toxicity	2	3
Alzheimer's Disease	3	3
Asthma	2	3
Atherosclerosis	3	3
Cadmium Poisoning	2	3
Cancers: Drug Resistant	2	3
Carcinoma: Non-Small-Cell Lung	1	3
Cardiovascular Diseases	2	3
Cervical Cancer	3	3
Chemotherapy-Induced Kidney Damage	2	3
Diabetes: Oxidative Stress	2	3
Enterovirus 71	2	3
Escherichia coli Infections	3	3
Influenza A	2	3
Kidney Cancer	2	3
Leukemia: Acute promyelocytic leukemia	3	3
Lipid Peroxidation	2	3
Myocardial Infarction	2	3
Psoriasis	2	3
Pulmonary Fibrosis	2	3
Rheumatoid Arthritis	2	3
Arthritis	1	2
Autoimmune Diseases	1	2
Bacterial Infections: Resistance/Biofilm Formation	2	2
Bladder Cancer	2	2
Bone Fractures	1	2
Brain Inflammation	1	2
Burns	1	2
Candida Albicans	2	2
Carcinoma: Small Cell Lung	1	2
Cholesterol: Oxidation	2	2
Colon Cancer	2	2
Diabetes	1	2
Diabetic Complications	1	2
Drug-Induced Toxicity: Indomethacin	1	2
Endometriosis	1	2
Esophageal Cancer	2	2
Excitotoxicity	1	2
Fractures: Bone	1	2
Gastric Cancer	2	2
Hyperglycemia	2	2
Hyperlipidemia	1	2
Hypertension: Pulmonary	1	2
Immune Dysregulation: TH1/TH2 imbalance	1	2
Influenza	2	2
Insomnia	1	2
Ischemia: Myocardial	1	2
Kidney Damage	1	2
Leishmaniasis	1	2
Liver Fibrosis	1	2
Lung Injury: Acute	1	2
MRSA	2	2
Macular Degeneration	1	2
Malaria	1	2
Mastitis	1	2
Melanoma	1	2
Memory Disorders: Sleep Deprivation Induced	1	2
Metabolic Syndrome X	1	2
Mycobacterium Infections	2	2
Neurodegenerative Diseases	1	2
Osteosarcoma	1	2
Ovarian Cancer	2	2
Pancreatic Cancer	2	2
Periodontitis	1	2
Prostate Cancer	2	2
Radiation	1	2
Respiratory Diseases	2	2
Sleep Disorders	1	2
Spinal Cord Injuries	1	2
Trypanosomiasis	1	2
Wound Healing	1	2
Wound Healing: Delayed	1	2
Acetaminophen (Tylenol) Toxicity	1	1
Acute Respiratory Distress Syndrome	1	1
Acute lymphoblastic leukemia (ALL)	1	1
Advanced Glycation End products (AGE)	1	1
Air Pollution Linked Toxicity	1	1
Allergies	1	1
Atopic Dermatitis	1	1
Bacillus Cereus infection	1	1
Bacillus subtilis infections	1	1
Bisphenol Toxicity	1	1
Brain Cancer	1	1
Cancer Metastasis	1	1
Cancers: Multi-Drug Resistant	1	1
Candida Glabrata	1	1
Candida Infection	1	1
Cardiomegaly	1	1
Cardiomyopathy	1	1
Chemotherapy-Induced Toxicity: Cisplatin	1	1
Chikungunya Virus	1	1
Cholera	1	1
Chronic Obstructive Pulmonary Disease	1	1
Cytomegalovirus Infections	1	1
Degenerative Disk Disease	1	1
Dengue	1	1
Depression	1	1
Depression: Breast Cancer Related	1	1
Encephalitis: Japanese	1	1
Endometrial Cancer	1	1
Endothelial Damage	1	1
Endothelial Dysfunction	1	1
Enterobacteriaceae Infections	1	1
Epstein-Barr Virus Infections	1	1
Fatty Liver	1	1
Food Allergies	1	1
Gastrointestinal Cancer	1	1
Glioblastoma	1	1
H1N1 Infection	1	1
HIV Infections	1	1
Haemophilus influenzae	1	1
Hashimoto's thyroiditis	1	1
Head and Neck Cancer	1	1
Heart Failure	1	1
Human Influenza	1	1
Hydrogen Peroxide Induced Toxicity	1	1
Hyperinsulinism	1	1
IgE-Mediated Hypersensitivity	1	1
Intestinal Permeability	1	1
Leukemia	1	1
Listeria Infections	1	1
Liver Damage	1	1
Liver Disease	1	1
Lung Cancer	1	1
Melanoma: Metastatic	1	1
Nasopharyngeal Cancer	1	1
Non-Small-Cell Lung Carcinoma	1	1
Oral Cancer	1	1
Pancreatic Cancer: Metastatic	1	1
Polio	1	1
Porphyromonas gingivalis	1	1
Promyelocytic leukemia	1	1
Pseudomonas aeruginosa	1	1
Pulmonary Fibrosis: Bleomycin-Induced	1	1
Respiratory Syncytial Virus Infections	1	1
Salmonella Infections	1	1
Snake Bite: Venom Toxicity	1	1
Streptococcus Infections	1	1
Triglycerides: Elevated	1	1
Varicella	1	1
Weight Problems	1	1

Name	AC	CK
Anti-Inflammatory Agents	52	84
Antioxidants	43	73
Neuroprotective Agents	14	39
Apoptotic	34	36
Antiproliferative	31	35
Anti-Apoptotic	17	33
Interleukin-6 Downregulation	16	26
Tumor Necrosis Factor (TNF) Alpha Inhibitor	15	25
Anti-metastatic	12	18
NF-kappaB Inhibitor	12	18
Antiviral Agents	16	17
Interleukin-1 beta downregulation	10	16
Cell cycle arrest	14	14
Hepatoprotective	8	14
Chemopreventive	9	13
Renoprotective	7	13
Chemotherapeutic	11	12
Cardioprotective	9	11
Hypoglycemic Agents	7	11
Hypolipidemic	5	9
Anti-Bacterial Agents	8	8
Autophagy Up-regulation	4	7
Immunomodulatory	5	7
MicroRNA modulator	6	7
Anti-Fibrotic	4	6
Chemoprotective Agents	4	6
Chemosensitizer	5	6
Osteoprotective	3	6
Antimutagenic Agents	1	5
Nrf2 activation	5	5
Postaglandin PGE2 downregulation	3	5
Antineoplastic Agents	3	4
Gastrointestinal Agents	2	4
Gastroprotective	2	4
Malondialdehyde Down-regulation	2	4
Matrix metalloproteinase-2 (MMP-2) inhibitor	3	4
Osteogenic	2	4
Bcl-2 protein down-regulation	3	3
Cyclooxygenase 2 Inhibitors	2	3
Enzyme Inhibitors	2	3
Matrix metalloproteinase-1 (MMP-1) inhibitor	2	3
Matrix metalloproteinase-9 (MMP-9) inhibitor	2	3
Nitric Oxide Inhibitor	2	3
Pancreato Protective Agents	2	3
Angiogenesis Inhibitors	2	2
Anti-Allergic Agents	2	2
Antihypertensive Agents	1	2
Antimalarials	1	2
Antinoceceptive	1	2
Cytoprotective	2	2
Excitatory Amino Acid Agonists	1	2
GABA Modulators	1	2
Heme oxygenase-1 up-regulation	2	2
Insulin Sensitizers	1	2
Interleukin-10 upregulation	2	2
Interleukin-18 down-regulation	1	2
Leishmanicidal	1	2
Matrix metalloproteinase-8 (MMP-8) inhibitor	1	2
Radioprotective	1	2
Radiosensitizer	1	2
SIRT1 Activator	1	2
STAT3 Inhibitor	1	2
Trypanocidal Agents	1	2
Tumor Suppressor Protein p53 Upregulation	2	2
Wnt/β-catenin signaling pathway modulation	1	2
15-Lipoxygenase (15-LOX) Inhibitor	1	1
Acetylcholinesterase Inhibitor	1	1
Alpha-amylase inhibitor	1	1
Alpha-glucosidase inhibitor	1	1
Anti-Asthmatic Agents	1	1
Anti-atherogenic	1	1
Anticarcinogenic Agents	1	1
Antimicrobial	1	1
Bcl-xL down-regulation	1	1
Cytotoxicity	1	1
Drug synergy	1	1
Epidermal growth factor receptor (EGFR) inhibitor	1	1
Estrogen Receptor Modulators	1	1
Hypoxia-inducible factor-1 (HIF-1) inhibitor	1	1
Interleukin-17 downregulation	1	1
Interleukin-23 Downregulation	1	1
Interleukin-5 downregulation	1	1
Multidrug Resistance Gene Modulators	1	1
Neurominidase Inhibitor	1	1
Phase II Detoxification Enzyme Inducer	1	1
Transforming growth factor beta (TGF-β) inhibitor	1	1
Vascular Endothelial Growth Factor Inhibitors	1	1
Vasodilator Agents	1	1
anti-inflammatory	1	1
interleukin-13 down-regulation	1	1

Additional Keywords : Plant Extracts

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An aqueous horseradish extract and its main flavonoids, kaempferol and quercetin has great potential to protect DNA from damage. Dec 31, 2013

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Pubmed Data : Molecules. 2014 ;19(3):3160-72. Epub 2014 Mar 14. PMID: 24637991

Article Published Date : Dec 31, 2013

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Activity of compounds from temperate propolis against Trypanosoma brucei and Leishmania mexicana Jun 25, 2021

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Pubmed Data : Endocrinology. 2023 Aug 28 ;164(10). PMID: 37652054

Article Published Date : Aug 27, 2023

Study Type : Animal Study

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Substances : Flavonoids, Kaempferol, Quercetin

Diseases : Endometriosis

Pharmacological Actions : Antiproliferative

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Galangin and kaempferol alleviate the indomethacin-caused cytotoxicity and barrier loss in rat intestinal epithelial cells.Jun 14, 2021

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Kaempferol downregulates TH2 cytokine production without inducing a TH1 pattern of inflammation in a manner that may have potential clinical use for the treatment of allergic asthma. Sep 12, 2009

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Pubmed Data : Int Immunopharmacol. 2009 Sep 12. PMID: 19755174

Article Published Date : Sep 12, 2009

Study Type : Animal Study

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Substances : Kaempferol

Diseases : Asthma, Immune Dysregulation: TH1/TH2 imbalance

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Kaempferol may have a therapeutic role in preventing and/or treating autoimmune diseases. Sep 15, 2007

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Pubmed Data : J Immunol. 2007 Sep 15;179(6):3881-7. PMID: 17785825

Article Published Date : Sep 15, 2007

Study Type : Animal Study

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Substances : Kaempferol

Diseases : Autoimmune Diseases

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Kaempferol may prove to be a novel agent for the treatment of liver fibrosis or other fibroproliferative diseases.Jul 04, 2019

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Pubmed Data : Curr Top Med Chem. 2022 Sep 7. Epub 2022 Sep 7. PMID: 36082856

Article Published Date : Sep 06, 2022

Study Type : Review

Additional Links

Substances : Kaempferol

Diseases : Cancers: All

Pharmacological Actions : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Anti-metastatic, Apoptotic

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Antioxidant and anti-inflammatory activities of the crude extracts of raw and fermented tomato pomace.Feb 20, 2020

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Pubmed Data : Antioxidants (Basel). 2020 Feb 21 ;9(2). Epub 2020 Feb 21. PMID: 32098217

Article Published Date : Feb 20, 2020

Study Type : In Vitro Study

Additional Links

Substances : Cinnamic acid, Fermented Foods and Beverages, Kaempferol, Naringenin , Tomato

Diseases : Inflammation, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

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Antioxidant and antiproliferative activities of kale and wild cabbageFeb 14, 2023

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Pubmed Data : Biomed Res Int. 2020 ;2020:5891016. Epub 2020 Oct 21. PMID: 33145355

In silico targeting SARS-CoV-2 spike protein and main protease by biochemical compounds.Sep 21, 2021

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Pubmed Data : Front Pharmacol. 2022 ;13:847113. Epub 2022 Jun 2. PMID: 35721162

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Pubmed Data : Endocrine. 2018 04 ;60(1):83-94. Epub 2018 Feb 1. PMID: 29392616

Article Published Date : Dec 31, 2017

Study Type : In Vitro Study

Additional Links

Substances : Kaempferol

Diseases : Cardiomyopathy, Hyperglycemia

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective, NF-kappaB Inhibitor, Nrf2 activation

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Kaempferol blocks neutrophil extracellular traps formation and reduces tumour metastasis.May 18, 2020

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Pubmed Data : J Cell Mol Med. 2020 May 19. Epub 2020 May 19. PMID: 32427405

Article Published Date : May 18, 2020

Study Type : In Vitro Study

Additional Links

Substances : Kaempferol

Diseases : Breast Cancer

Pharmacological Actions : Anti-metastatic

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Kaempferol can reverse the 5-Fu resistance of colorectal cancer cells.Mar 23, 2022

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Pubmed Data : Int J Mol Sci. 2022 Mar 24 ;23(7). Epub 2022 Mar 24. PMID: 35408903

Article Published Date : Mar 23, 2022

Study Type : In Vitro Study

Additional Links

Substances : Kaempferol

Diseases : Cancers: Drug Resistant, Colon Cancer, Colorectal Cancer

Pharmacological Actions : Chemosensitizer

Additional Keywords : Chemothapeutic Synergy: 5-flourouracil

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Kaempferol combined with ABT-199 has a potential application prospect in the treatment of hepatocellular carcinoma.Dec 31, 2021

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Pubmed Data : J BUON. 2019 Jul-Aug;24(4):1555-1561. PMID: 31646808

Article Published Date : Jun 30, 2019

Study Type : In Vitro Study

Additional Links

Substances : Kaempferol

Diseases : Endometrial Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest

Additional Keywords : Selective Cytotoxicity

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Kaempferol derivatives as antiviral drugs against the 3a channel protein of coronavirus.Feb 01, 2014

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Pubmed Data : Planta Med. 2014 Feb ;80(2-3):177-82. Epub 2014 Jan 23. PMID: 24458263

Article Published Date : Feb 01, 2014

Study Type : In Vitro Study

Additional Links

Substances : Kaempferol

Diseases : Coronavirus Disease (Covid-19), Coronavirus Infection

Pharmacological Actions : Antiviral Agents

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Kaempferol efficacy in metabolic diseases: Molecular mechanisms of action in diabetes mellitus, obesity, non-alcoholic fatty liver disease, steatohepatitis, and atherosclerosis.May 05, 2024

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Pubmed Data : Biomed Pharmacother. 2024 May 6 ;175:116694. Epub 2024 May 6. PMID: 38713943

Article Published Date : May 05, 2024

Study Type : Review

Additional Links

Substances : Kaempferol

Diseases : Atherosclerosis, Nonalcoholic fatty liver disease (NAFLD), Obesity

Pharmacological Actions : Anti-atherogenic, Anti-Inflammatory Agents, Antioxidants, NF-kappaB Inhibitor, Nrf2 activation

Additional Keywords : Anti-Obesity Agents

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Kaempferol enhances intestinal barrier function.Jan 01, 2011

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Pubmed Data : J Nutr. 2011 Jan;141(1):87-94. Epub 2010 Nov 10. PMID: 21068182

Article Published Date : Jan 01, 2011

Study Type : In Vitro Study

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Substances : Kaempferol

Diseases : Intestinal Permeability

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Kaempferol exerts anti-proliferative effects on human ovarian cancer cells.Apr 30, 2019

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Pubmed Data : Phytomedicine. 2023 Sep ;118:154942. Epub 2023 Jun 23. PMID: 37421767

Article Published Date : Aug 31, 2023

Study Type : In Vitro Study

Additional Links

Substances : Kaempferol

Diseases : Coronavirus Disease (Covid-19)

Pharmacological Actions : Antiviral Agents

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Kaempferol inhibits the primary attachment phase of biofilm formation in Staphylococcus aureus.Dec 31, 2016

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Pubmed Data : J Physiol Biochem. 2016 Mar 21. Epub 2016 Mar 21. PMID: 27000882

Article Published Date : Mar 20, 2016

Study Type : In Vitro Study

Additional Links

Substances : Kaempferol

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Kaempferol may serve as a novel target for treatment of Intervertebral disc degeneration.Dec 29, 2016

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Pubmed Data : Int Immunopharmacol. 2016 Dec 30 ;43:236-242. Epub 2016 Dec 30. PMID: 28043032

Article Published Date : Dec 29, 2016

Study Type : In Vitro Study

Additional Links

Substances : Kaempferol

Diseases : Degenerative Disk Disease

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation

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Kaempferol might improve bleomycin-induced fibrosis by reducing oxidative stress, inflammation, and oxidative cellular damage.Sep 30, 2019

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Pubmed Data : Neurochem Res. 2019 Nov 25. Epub 2019 Nov 25. PMID: 31768814

Article Published Date : Nov 24, 2019

Study Type : In Vitro Study

Additional Links

Substances : Kaempferol

Diseases : Cadmium Poisoning

Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents

Problem Substances : Cadmium

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Kaempferol protects blood vessels from damage induced by oxidative stress and inflammation.Dec 31, 2019

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Kaempferol suppresses human gastric cancer SNU-216 cell proliferation and promotes cell autophagy.Feb 13, 2019

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Pubmed Data : J Food Biochem. 2020 Jan 3:e13137. Epub 2020 Jan 3. PMID: 31899556

Article Published Date : Jan 02, 2020

Study Type : In Vitro Study

Additional Links

Substances : Banana, Kaempferol, Rutin

Diseases : Alzheimer's Disease, Diabetes Mellitus: Type 2, Inflammation

Pharmacological Actions : 15-Lipoxygenase (15-LOX) Inhibitor, Acetylcholinesterase Inhibitor, Alpha-amylase inhibitor, Alpha-glucosidase inhibitor , Anti-Inflammatory Agents, Enzyme Inhibitors

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MiR-21 mediates the protection of kaempferol against hypoxia/reoxygenation-induced cardiomyocyte injury.Dec 31, 2019

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Targeting SARS-CoV-2 spike protein of COVID-19 with naturally occurring phytochemicals.Jul 21, 2020

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Pubmed Data : J Biomol Struct Dyn. 2020 Jul 22:1-11. Epub 2020 Jul 22. PMID: 32698689

Article Published Date : Jul 21, 2020

Study Type : In Vitro Study

Additional Links

Substances : Fisetin, Kaempferol, Quercetin

Diseases : Coronavirus Infection

Pharmacological Actions : Antiviral Agents

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Tart cherry extract inhibits the mitochondrial apoptotic cell death elicited by airborne PM 10 in human epidermal keratinocytes.Mar 12, 2021

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Pubmed Data : Biomed Pharmacother. 2019 Sep ;117:109086. Epub 2019 Jun 11. PMID: 31200254

Article Published Date : Aug 31, 2019

Study Type : Review

Additional Links

Substances : Kaempferol

Diseases : Breast Cancer

Pharmacological Actions : Chemopreventive, Chemotherapeutic

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The ORF3a viroporin of SARS-CoV-2 may indeed be a promising target for antiviral substances.Mar 31, 2023

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Pubmed Data : Sci Rep. 2023 Apr 1 ;13(1):5328. Epub 2023 Apr 1. PMID: 37005439

Article Published Date : Mar 31, 2023

Study Type : In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Flavonoids, Kaempferol, Nobiletin , Quercetin

Diseases : Coronavirus Disease (Covid-19)

Pharmacological Actions : Antiviral Agents

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View the Evidence: 218 Abstracts with Kaempferol Research

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Association between dietary flavonol intake and mortality risk.Feb 24, 2024

Flavonol intake and cognitive decline in middle-aged adults.Nov 30, 2015

Sea buckthorn leaf extracts protect neuronal PC-12 cells from oxidative stress.Jul 27, 2017

An aqueous horseradish extract and its main flavonoids, kaempferol and quercetin has great potential to protect DNA from damage. Dec 31, 2013

Harmine and Kaempferol treatment enhances NFATC1 and FOXP3 mediated regulatory T-cells' suppressive capacity in generalized vitiligo.Nov 30, 2023

Immunomodulatory effects of Kaempferol on microglial and Macrophage cells during the progression of diabetic retinopathy.Apr 14, 2024

Kaempferol promotes non-small cell lung cancer cell autophagy via restricting Met pathway.Sep 15, 2023

Preparation, characterization, and evaluation of the antitumor effect of kaempferol nanosuspensions.May 05, 2023

A enriched Mongolian oak cups extract could exert anti-diabetic effects through alleviating types 1 and 2 diabetes and their complications.Apr 29, 2018

Activity of compounds from temperate propolis against Trypanosoma brucei and Leishmania mexicana Jun 25, 2021

Ameliorative effect of kaempferol, a flavonoid, on oxidative stress in streptozotocin-induced diabetic rats.Aug 31, 2015

Antiviral efficacy of flavonoids against enterovirus 71 infection.Jul 06, 2019

Dietary flavonoid kaempferol inhibits glucocorticoid-induced bone loss by promoting osteoblast survival.Feb 12, 2018

Dietary intake of kaempferol ameliorated hyperglycemia and improved insulin levels in middle-aged obese diabetic mice.Dec 31, 2014

Dietary kaempferol suppresses inflammation of dextran sulfate sodium-induced colitis.Jan 31, 2012

E. sativa might be beneficial in chronic diabetes in ameliorating the progression of diabetic neuropathy.Jul 31, 2018

Evaluation of inhibitory effects of flavonoids on breast cancer resistance protein.Sep 04, 2019

Flavonoids quercetin and kaempferol are NR4A1 antagonists and suppress endometriosis.Aug 27, 2023

Galangin and kaempferol alleviate the indomethacin-caused cytotoxicity and barrier loss in rat intestinal epithelial cells.Jun 14, 2021

Kaempferide improves glycolipid metabolism disorder by activating PPARγ in high-fat-diet-fed mice.Mar 31, 2021

Kaempferide protects against myocardial ischemia/reperfusion injury.Dec 31, 2016

Kaempferol addition increases the antimalarial activity of artesunate.Dec 31, 2019

Kaempferol alleviates acute alcoholic liver injury in mice.Nov 26, 2019

Kaempferol alleviates insulin resistance via hepatic IKK/NF-κB signal in type 2 diabetic rats.Aug 31, 2015

Kaempferol alleviates murine experimental colitis.Dec 31, 2020

Kaempferol ameliorated alcoholic liver disease.Oct 31, 2023

Kaempferol ameliorates H9N2 swine influenza virus-induced acute lung injury.Apr 30, 2017

Kaempferol ameliorates pulmonary vascular remodeling in chronic hypoxia-induced pulmonary hypertension.Apr 30, 2023

Kaempferol ameliorates symptoms of metabolic syndrome.Jul 18, 2021

Kaempferol and Catechin produced a concentration dependent anti-fibrillogenic effects.Jul 28, 2015

Kaempferol and chrysin have synergistic effects to improve septic mice survival.Jan 05, 2017

Kaempferol appears to be an effective topical wound healing agent in the treatment of both nondiabetic and diabetic wounds.Dec 31, 2018

Kaempferol attenuated diabetic nephropathy by reducing apoptosis and promoting autophagy through AMPK/mTOR pathways.Dec 31, 2021

Kaempferol attenuated myocardial ischemia-reperfusion injury in diabetic ratsMay 14, 2017

Kaempferol attenuates doxorubicin-induced renal tubular injury.Dec 31, 2022

Kaempferol attenuates imiquimod-induced psoriatic skin inflammation in a mouse model.Aug 12, 2019

Kaempferol attenuates neuroinflammation and blood brain barrier dysfunction to improve neurological deficits in cerebral ischemia/reperfusion.Jul 31, 2019

Kaempferol attenuates nonalcoholic fatty liver disease in type 2 diabetes.Aug 31, 2023

Kaempferol attenuates streptozotocin-induced diabetic nephropathy.Nov 01, 2020

Kaempferol can safely inhibit the metastasis of the 786-O RCC cells into the lungs by about 87.4%.Dec 31, 2016

Kaempferol downregulates TH2 cytokine production without inducing a TH1 pattern of inflammation in a manner that may have potential clinical use for the treatment of allergic asthma. Sep 12, 2009

Kaempferol exhibits anti-pyroptosis activities.Sep 30, 2019

Kaempferol has the potential to restore deranged activity of membrane-bound ATPases in STZ-induced diabetic rats.Apr 07, 2015

Kaempferol has therapeutic value in thermal burn-induced skin injuries.Jan 01, 2010

Kaempferol improves acute kidney injury via inhibition of macrophage infiltration in septic mice.Jul 25, 2023

Kaempferol increased tumor cell killing by radiation in vitro and in vivo through inhibition of the AKT/PI3K and ERK pathways and activation of the mitochondria apoptosis pathwayAug 18, 2015

Kaempferol induces programmed cell death in human osteosarcoma cells.Nov 01, 2010

Kaempferol inhibits the migration and invasion of rheumatoid arthritis fibroblast-like synoviocytes.Dec 17, 2017

Kaempferol inhibits the progression of silica-induced pulmonary fibrosis.Sep 26, 2019

Kaempferol may be useful in decreasing alveolar bone resorption, attachment loss and MMP-1 and -8 production in experimental periodontitis.Mar 31, 2016

Kaempferol may have a therapeutic role in preventing and/or treating autoimmune diseases. Sep 15, 2007

Kaempferol may prove to be a novel agent for the treatment of liver fibrosis or other fibroproliferative diseases.Jul 04, 2019

Kaempferol might act as a therapeutic potential candidate for cancer metastasis.Jan 31, 2015

Kaempferol might be a novel promising therapeutic agent for spinal cord injury.Apr 02, 2021

Kaempferol promotes bone formation in part via the mTOR signaling pathway.Nov 30, 2019

Kaempferol protects against doxorubicin-induced cardiotoxicity in vivo and in vitro.Feb 05, 2012

Kaempferol protects against gamma radiation-induced mortality and damage.Apr 19, 2018

Kaempferol protects against retinal photoreceptor degeneration in a mouse model of light-induced retinal injury.Dec 13, 2022

Kaempferol stimulates WNT/β-catenin signaling pathway to induce differentiation of osteoblasts.Aug 30, 2019

kaempferol-3-O-glucorhamnosidein a potent anti-inflammatory in vitro and in vivo.Dec 06, 2018

Kaempferol-3-O-glucuronide ameliorates non-alcoholic steatohepatitis.May 13, 2021

Nanoparticles containing astaxanthin and kaempferol holds promising therapeutic potential in the treatment of non-alcoholic fatty liver disease.Nov 29, 2023

Oral administration of apigenin significantly reduced elevated levels of SASP and IκBζ mRNA in the kidneys of aged rats.Jun 16, 2015

Oral administration of kaempferol inhibits bone loss in rat model of ovariectomy-induced osteopenia.Sep 30, 2017

Polyphenols can be promising in combating diabetic neuropathy-associated damaging pathways.Dec 31, 2020

Protective effects of kaempferol on lipopolysaccharide-induced mastitis in mice.Sep 30, 2014

Quercetin, kaempferol and biapigenin from St. John's wort are neuroprotective against excitotoxicity. May 01, 2008

Rebalancing of the gut flora and microbial metabolism is responsible for the anti-arthritis effect of kaempferol.Aug 18, 2019

Synergistic effect of chrysin and kaempferol in ameliorating cerebral ischemic reperfusion injury.May 28, 2024

Tea seed kaempferol triglycoside attenuates LPS-induced systemic inflammation and ameliorates cognitive impairments.Mar 21, 2022

The concomitant reduction in COX-2 expression in paw tissues suggested kaempferol's role in mitigation of inflammation by targeting STAT3 and NF-κB.Nov 30, 2017

The obtained data provide evidences that kaempferol pre-treatment has the protective effect to preserve the cortical tissues in cadmium-exposed rats.Nov 02, 2020

Kaempferol

View the Evidence:
218 Abstracts with Kaempferol Research