Hops

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67 Diseases Researched for Hops
NameACCKFocus
Osteoporosis322Locked
Obesity618Locked
Menopausal Syndrome314Locked
Inflammation711Locked
Anxiety110Locked
Depression110Locked
Insomnia110Locked
Overactive Bladder110Locked
Overweight 110Locked
Lipopolysaccharide-Induced Toxicity47Locked
Arthritis24Locked
Acne23Locked
Breast Cancer33Locked
Cancers: All33Locked
Aging12Locked
Alcoholic Liver Disease12Locked
Allergic Rhinitis12Locked
Atherosclerosis12Locked
Fibrosis: Liver12Locked
Gout12Locked
HDL: Low12Locked
Hepatic Steatosis12Locked
Hyperlipidemia12Locked
Hyperuricemia12Locked
Infection: Antibiotic Resistant22Locked
Liver Cancer22Locked
Liver Damage12Locked
Metabolic Syndrome X22Locked
Nonalcoholic fatty liver disease (NAFLD)12Locked
Osteoarthritis12Locked
Pelvic Inflammatory Disease12Locked
Periodontal Diseases22Locked
Prostate Cancer22Locked
Triglycerides: Elevated12Locked
Acute lymphoblastic leukemia (ALL)11Locked
Alzheimer's Disease11Locked
Bacterial Infections11Locked
Burkitt Lymphoma11Locked
Cancer Metastasis11Locked
Cardiovascular Diseases11Locked
Choriocarcinoma11Locked
Cytomegalovirus Infections11Locked
Diabetes Mellitus: Type 211Locked
Diarrhea11Locked
Gram-Positive Bacterial Infections11Locked
Hepatitis C11Locked
Herpes family viruses11Locked
Hydrogen Peroxide Induced Toxicity11Locked
Hyperglycemia11Locked
Influenza11Locked
Leukemia: Chronic Lymphocytic Leukemia (CLL)11Locked
Liver Fibrosis11Locked
Lymphoma11Locked
Metabolic Diseases11Locked
Neurodegenerative Diseases11Locked
Oral Cancer11Locked
Oxidative Stress11Locked
Photooxidative Stress11Locked
Porphyromonas gingivalis11Locked
Rhinovirus Infection 11Locked
Sleep Disorders11Locked
Squamous cell carcinoma11Locked
Staphylococcal Infections11Locked
Staphylococcus aureus infection11Locked
Trophoblastic Neoplasms11Locked
Trophoblastic Tumor11Locked
Ultraviolet Radiation Induced Damage11Locked
45 Pharmacological Actions Researched for Hops
NameACCKFocus
Anti-Inflammatory Agents1016Locked
Antioxidants811Locked
Anti-Anxiety Agents110Locked
Antidepressive Agents110Locked
Interleukin-6 Downregulation58Locked
Hypolipidemic46Locked
Neuroprotective Agents36Locked
Anti-Bacterial Agents45Locked
Antiproliferative 55Locked
Apoptotic55Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor35Locked
Chemopreventive44Locked
Osteoprotective 24Locked
Cyclooxygenase 2 Inhibitors23Locked
Alpha-amylase inhibitor12Locked
Anti-Allergic Agents12Locked
Anti-Apoptotic12Locked
Anti-Fibrotic12Locked
Anti-metastatic22Locked
Antiviral Agents22Locked
Aromatase Inhibitors22Locked
Catalase Up-Regulation12Locked
Hepatoprotective12Locked
Histamine Antagonists12Locked
Hypoglycemic Agents22Locked
Immunomodulatory12Locked
Interleukin-1 beta downregulation12Locked
Postaglandin PGE2 downregulation 12Locked
Prophylactic Agents12Locked
Renoprotective12Locked
Superoxide Dismutase Up-regulation12Locked
Uricosuric Agents12Locked
Alpha-glucosidase inhibitor 11Locked
Angiogenesis Inhibitors11Locked
Anti-Platelet11Locked
Antimicrobial11Locked
Cell cycle arrest11Locked
Enzyme Inhibitors11Locked
GABA Modulators11Locked
Gastrointestinal Agents11Locked
Interleukin-8 downregulation11Locked
Matrix metalloproteinase-1 (MMP-1) inhibitor11Locked
Matrix metalloproteinase-9 (MMP-9) inhibitor11Locked
NF-kappaB Inhibitor11Locked
Photoprotective11Locked
Related Topics

Hops is a Sub of the following Topic

View the Evidence:
73 Abstracts with Hops Research

[+]

A combination of valerian and hops reduces sleep latency in patients suffering from non-organic insomnia. Sep 01, 2007

Pubmed Data : Phytother Res. 2007 Sep;21(9):847-51. PMID: 17486686
Article Published Date : Sep 01, 2007
Study Type : Human Study
Additional Links
Substances : Hops, Valerian
Diseases : Insomnia
[+]

Beer drinking contributes to higher bone density as a result of the phytoestrogen content (hops) of this alcoholic beverage. Oct 01, 2009

Pubmed Data : Nutrition. 2009 Oct;25(10):1057-63. Epub 2009 Jun 13. PMID: 19527924
Article Published Date : Oct 01, 2009
Study Type : Human Study
Additional Links
Substances : Beer, Hops, phytoestrogens
Diseases : Osteoporosis
[+]

Cucurbita pepo-Rhus aromatica-Humulus lupulus combination reduces overactive bladder symptoms in women.Jun 30, 2019

Pubmed Data : Planta Med. 2019 Jul 1. Epub 2019 Jul 1. PMID: 31261419
Article Published Date : Jun 30, 2019
Study Type : Human Study
Additional Links
Substances : Hops, Pumpkin
Diseases : Overactive Bladder
Additional Keywords : Plant Extracts
[+]

Daily supplementation with a hops dry extract can significantly improve mild depression, anxiety and stress symptoms.Mar 31, 2017

Pubmed Data : Hormones (Athens). 2017 Apr ;16(2):171-180. PMID: 28742505
Article Published Date : Mar 31, 2017
Study Type : Human Study
Additional Links
Substances : Hops
Diseases : Anxiety, Depression
Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents
Additional Keywords : Plant Extracts
[+]

Hop effectively reduced the early menopausal symptoms in this study. May 11, 2015

Pubmed Data : Complement Ther Clin Pract. 2015 May 12. Epub 2015 May 12. PMID: 25982391
Article Published Date : May 11, 2015
Study Type : Human Study
Additional Links
Substances : Hops
Diseases : Menopausal Syndrome
Additional Keywords : Significant Treatment Outcome
[+]

Hop rho iso-alpha acids, berberine, vitamin D(3) and vitamin K (1) favorably impact biomarkers of bone turnover in postmenopausal women. Dec 19, 2009

Pubmed Data : J Bone Miner Metab. 2009 Dec 19. Epub 2009 Dec 19. PMID: 20024591
Article Published Date : Dec 19, 2009
Study Type : Human Study
Additional Links
Substances : Berberine, Hops, Vitamin D, Vitamin K
Diseases : Osteoporosis
[+]

Matured hop extract safely reduces body fat, particularly the abdominal visceral fat of healthy overweight subjects.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr J. 2016 ;15(1):25. Epub 2016 Mar 9. PMID: 26960416
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Substances : Hops
Diseases : Obesity, Overweight
Additional Keywords : Anti-Obesity Agents, Plant Extracts
[+]

An ethanol extracts of Humulus lupulus could partially prevent ovariectomy-induced bone loss.Oct 14, 2017

Pubmed Data : Phytomedicine. 2017 Oct 15 ;34:50-58. Epub 2017 Aug 2. PMID: 28899509
Article Published Date : Oct 14, 2017
Study Type : Animal Study
Additional Links
Substances : Hops
Diseases : Menopausal Syndrome, Osteoarthritis
Pharmacological Actions : Osteoprotective
Additional Keywords : Plant Extracts
[+]

An iso-α-acid-rich extract from hops attenuates acute alcohol-induced liver steatosis in mice.Dec 31, 2017

Pubmed Data : Nutrition. 2018 Jan ;45:68-75. Epub 2017 Jul 27. PMID: 29129239
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Hops
Diseases : Alcoholic Liver Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation
[+]

Anti-atherogenic effect of Humulus japonicus in apolipoprotein E-deficient mice.Sep 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2016 Oct ;38(4):1101-10. Epub 2016 Sep 1. PMID: 27600281
Article Published Date : Sep 30, 2016
Study Type : Animal Study
Additional Links
Substances : Hops
Diseases : Atherosclerosis, Inflammation
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Combination of red clover and hops extract improved menopause symptoms.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2020 ;2020:7941391. Epub 2020 May 23. PMID: 32595737
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Hops, Red Clover
Diseases : Menopausal Syndrome
Pharmacological Actions : Antioxidants, Hypolipidemic
[+]

Compounds found in hops have antibacterial activity against acne-causing bacteria. Jul 01, 2007

Pubmed Data : Pest Manag Sci. 2007 Jul;63(7):625-7. PMID: 19201179
Article Published Date : Jul 01, 2007
Study Type : Animal Study
Additional Links
Substances : Hops
Diseases : Acne
Pharmacological Actions : Anti-Bacterial Agents
[+]

Dietary isohumulones, the bitter components of beer, raise plasma HDL-cholesterol levels and reduce liver cholesterol and triacylglycerol contents in mice. Apr 01, 2005

Pubmed Data : Br J Nutr. 2005 Apr;93(4):559-67. PMID: 15946420
Article Published Date : Apr 01, 2005
Study Type : Animal Study
Additional Links
Substances : Beer, Hops
Diseases : HDL: Low, Triglycerides: Elevated
[+]

Hop extract is a promising candidate for an effective prophylactic for Alzheimer disease.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2014 ;9(1):e87185. Epub 2014 Jan 29. PMID: 24489866
Article Published Date : Dec 31, 2013
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Hops
Pharmacological Actions : Neuroprotective Agents, Prophylactic Agents
Additional Keywords : Plant Extracts
[+]

Hop extracts may be effective in the relief of symptoms of allergic rhinitis.Apr 01, 2006

Pubmed Data : Biol Pharm Bull. 2006 Apr;29(4):689-92. PMID: 16595900
Article Published Date : Apr 01, 2006
Study Type : Animal Study
Additional Links
Substances : Hops
Diseases : Allergic Rhinitis
Pharmacological Actions : Anti-Allergic Agents, Histamine Antagonists
Additional Keywords : Plant Extracts
[+]

Hops (H. lupulus) has anti-inflammatory activity in a mouse model of athritis. Jul 16, 1996

Pubmed Data : Biochem Biophys Res Commun. 1996 Jul 16;224(2):358-61. PMID: 16534727
Article Published Date : Jul 16, 1996
Study Type : Animal Study
Additional Links
Substances : Hops
Diseases : Arthritis, Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Cyclooxygenase 2 Inhibitors, Postaglandin PGE2 downregulation
Additional Keywords : Plant Extracts
[+]

Hops extract and xanthohumol ameliorate bone loss induced by iron overload via activating Akt/GSK3β/Nrf2 pathway.Jan 31, 2022

Pubmed Data : J Bone Miner Metab. 2022 Feb 1. Epub 2022 Feb 1. PMID: 35106609
Article Published Date : Jan 31, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Hops, Xanthohumol
Diseases : Iron Overload
Pharmacological Actions : Nrf2 activation, Osteoprotective
[+]

Humulus japonicas may have therapeutic potential to protect dopaminergic neuron degeneration in Parkinson's disease.Jan 31, 2017

Pubmed Data : J Med Food. 2017 Feb ;20(2):116-123. PMID: 28146406
Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Hops
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Humulus japonicus could alleviate the high fat diet-induced obesity and decrease the dyslipidemia profiles.Sep 28, 2018

Pubmed Data : J Med Food. 2018 Sep 29. Epub 2018 Sep 29. PMID: 30273090
Article Published Date : Sep 28, 2018
Study Type : Animal Study
Additional Links
Substances : Hops
Diseases : Hyperlipidemia, Obesity
Pharmacological Actions : Hypolipidemic
Additional Keywords : Anti-Obesity Agents
[+]

Humulus japonicus extract ameliorates collagen‑induced arthritis.Jan 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2020 Feb ;45(2):417-428. Epub 2019 Dec 3. PMID: 31894253
Article Published Date : Jan 31, 2020
Study Type : Animal Study
Additional Links
Substances : Hops
Diseases : Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-6 Downregulation
Additional Keywords : Plant Extracts
[+]

Humulus japonicus extract exhibits antioxidative and anti-aging effects via modulation of the AMPK-SIRT1 pathway.Apr 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2015 May ;9(5):1819-1826. Epub 2015 Feb 17. PMID: 26136899
Article Published Date : Apr 30, 2015
Study Type : Animal Study
Additional Links
Substances : Hops
Diseases : Aging
Pharmacological Actions : Antioxidants
[+]

Humulus japonicus extract improved the gastrointestinal disorders induced by water avoidance stress.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2022 ;2022:9993743. Epub 2022 Jan 21. PMID: 35096122
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Hops
Diseases : Dehydration, Dysbiosis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents
Additional Keywords : Polysaccharides
[+]

Humulus japonicus extracts protect against lipopolysaccharide/d-galactosamine-induced acute liver injury in rats.Sep 30, 2018

Pubmed Data : J Med Food. 2018 Oct ;21(10):1009-1015. PMID: 30334699
Article Published Date : Sep 30, 2018
Study Type : Animal Study
Additional Links
Substances : Hops
Diseases : Lipopolysaccharide-Induced Toxicity, Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Catalase Up-Regulation, Hepatoprotective, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Humulus japonicus has a beneficial effect on cognitive impairment and neuroinflammation induced by systemic inflammation and on amnesia.Jul 18, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Lab Anim Res. 2022 Jul 19 ;38(1):21. Epub 2022 Jul 19. PMID: 35854340
Article Published Date : Jul 18, 2022
Study Type : Animal Study
Additional Links
Substances : Hops
Diseases : Cognitive Decline/Dysfunction, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-12 downregulation, Neuroprotective Agents
[+]

Humulus japonicus inhibits the progression of Alzheimer's disease.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2017 Jan ;39(1):21-30. Epub 2016 Nov 16. PMID: 28004107
Article Published Date : Dec 31, 2016
Study Type : Transgenic Animal Study
Additional Links
Substances : Hops
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Humulus japonicus rescues autistic‑like behaviours.May 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2021 Jun ;23(6). Epub 2021 Apr 21. PMID: 33880583
Article Published Date : May 31, 2021
Study Type : Animal Study
Additional Links
Substances : Hops
Diseases : Autism
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents
[+]

Humulus lupulus L. extract and its active constituent xanthohumol attenuate oxidative stress and nerve injury induced by iron overload.Sep 07, 2022

Pubmed Data : J Nat Med. 2022 Sep 8. Epub 2022 Sep 8. PMID: 36074228
Article Published Date : Sep 07, 2022
Study Type : Animal Study
Additional Links
Substances : Hops, Xanthohumol
Diseases : Iron Overload
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Nrf2 activation
[+]

Humulus lupulus L. extract may protect against bone loss, and have potentials in the treatment of osteoporosis.Mar 26, 2019

Pubmed Data : Chin J Integr Med. 2019 Mar 27. Epub 2019 Mar 27. PMID: 30919241
Article Published Date : Mar 26, 2019
Study Type : Animal Study
Additional Links
Substances : Hops
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Inhibitory effects of Humulus japonicus extract against hepatic injury in a diabetic rat model.Jun 30, 2021

Pubmed Data : Food Sci Biotechnol. 2021 Jul ;30(7):979-988. Epub 2021 Jul 6. PMID: 34395029
Article Published Date : Jun 30, 2021
Study Type : Animal Study
Additional Links
Substances : Hops
Diseases : Diabetic Complications, Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective
[+]

Iso-alpha acids from hops inhibit hepatic steatosis, inflammation, and fibrosis.Nov 30, 2018

Pubmed Data : Lab Invest. 2018 Dec ;98(12):1614-1626. Epub 2018 Aug 8. PMID: 30089858
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Hops
Diseases : Fibrosis: Liver, Hepatic Steatosis, Inflammation, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents
[+]

Modulation of the TLR4/MyD88/NF- κ B pathway by Humulus japonicus extract protects against alcohol-induced liver injury.Dec 31, 2020

Pubmed Data : J Med Food. 2021 Jan ;24(1):18-27. Epub 2020 Dec 7. PMID: 33290158
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Hops
Diseases : Alcoholic Liver Disease, Oxidative Stress
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Hepatoprotective, Nrf2 activation
Additional Keywords : Plant Extracts
[+]

Natural compounds from Cortex Phellodendri and Humulus japonicus had anti-inflammatory effects on pelvic inflammatory disease.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Med Sci. 2017 ;14(8):729-734. Epub 2017 Jul 18. PMID: 28824307
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Hops
Diseases : Pelvic Inflammatory Disease
Pharmacological Actions : Anti-Inflammatory Agents
[+]

The antifungal mechanism of isoxanthohumol from Humulus lupulus.Oct 06, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2021 Oct 7 ;22(19). Epub 2021 Oct 7. PMID: 34639194
Article Published Date : Oct 06, 2021
Study Type : Animal Study
Additional Links
Substances : Hops
Diseases : Fungus Diseases
Pharmacological Actions : Antifungal Agents
[+]

Total flavonoids of Humulus lupulus could be used as a promising drug or ingredient for treatment of hyperuricemia and gout.Feb 28, 2017

Pubmed Data : Pak J Pharm Sci. 2017 Mar ;30(2):493-497. PMID: 28649075
Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Substances : Hops
Diseases : Gout, Hyperuricemia
Pharmacological Actions : Renoprotective, Uricosuric Agents
[+]

Xanthohumol alone may exert anti-obesity effects.Apr 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Oleo Sci. 2017 May 1 ;66(5):531-541. Epub 2017 Apr 13. PMID: 28413193
Article Published Date : Apr 30, 2017
Study Type : Animal Study
Additional Links
Substances : Hops, Xanthohumol
Diseases : Obesity
Pharmacological Actions : Alpha-amylase inhibitor
Additional Keywords : Anti-Obesity Agents
[+]

Xanthohumol-rich hop extract may exert preventive function on the increase of body weight and tissue triacylglycerol levels by overnutrition.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Oleo Sci. 2014 ;63(2):159-68. Epub 2014 Jan 14. PMID: 24420065
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Hops, Xanthohumol
Diseases : Obesity
Additional Keywords : Anti-Obesity Agents, Plant Extracts
[+]

A hops extract inhibited the cell proliferation in a time dependent manner in Hep3B cells with 70% inhibition.Feb 15, 2015

Pubmed Data : J Enzyme Inhib Med Chem. 2015 Feb 16:1-9. Epub 2015 Feb 16. PMID: 25683080
Article Published Date : Feb 15, 2015
Study Type : In Vitro Study
Additional Links
Substances : Hops
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Enzyme Inhibitors
Additional Keywords : Plant Extracts
[+]

A review of the anticancer activity and mechanism of xanthohumol.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:530. Epub 2018 May 22. PMID: 29872398
Article Published Date : Dec 31, 2017
Study Type : Review
Additional Links
Substances : Hops, Xanthohumol
Diseases : Cancers: All
Pharmacological Actions : Antiproliferative , Apoptotic, Chemopreventive
[+]

A variety of nutraceutical strategies hold promise in the prevention of Alzheimer disease.Jan 01, 2006

Pubmed Data : Med Hypotheses. 2006;67(4):682-97. Epub 2006 Jul 7. PMID: 16828233
Article Published Date : Jan 01, 2006
Study Type : Commentary
Additional Links
Substances : Chromium, Cinnamon, Cocoa, DHA (Docosahexaenoic Acid), Fish Oil, Folic Acid , Genistein, Hops, Policosanol, Sesame Seeds, Vitamin D
Diseases : Alzheimer's Disease, Neurodegenerative Diseases
[+]

Analyzing bioactive effects of the minor hop compound xanthohumol C on human breast cancer cells using quantitative proteomics.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2019 ;14(3):e0213469. Epub 2019 Mar 15. PMID: 30875365
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Hops, Xanthohumol
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Cell cycle arrest
Additional Keywords : Plant Extracts
[+]

Anti-inflammatory markers of hops cultivars evaluated by untargeted metabolomics strategy.Mar 31, 2022

Pubmed Data : Chem Biodivers. 2022 Apr ;19(4):e202100966. Epub 2022 Mar 22. PMID: 35267234
Article Published Date : Mar 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Hops
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Postaglandin PGE2 downregulation
[+]

Antibiofilm activity of bioactive hop compounds toward susceptible and resistant staphylococci.Jan 29, 2018

Pubmed Data : Res Microbiol. 2018 Jan 30. Epub 2018 Jan 30. PMID: 29407045
Article Published Date : Jan 29, 2018
Study Type : In Vitro Study
Additional Links
Substances : Hops
Diseases : Infection: Antibiotic Resistant, Staphylococcal Infections
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Biofilm
[+]

Apple and Hop-polyphenols inhibit P. gingivalis-mediated precursor of MMP-9 activation and invasion of oral squamous cell carcinoma cells.May 12, 2016

Pubmed Data : J Periodontol. 2016 May 13:1-21. Epub 2016 May 13. PMID: 27177287
Article Published Date : May 12, 2016
Study Type : In Vitro Study
Additional Links
Substances : Apple Polyphenols, Hops
Diseases : Oral Cancer, Periodontal Diseases, Squamous cell carcinoma
Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Apple- and hop-polyphenols protect periodontal ligament cells stimulated with enamel matrix derivative from Porphyromonas gingivalis.Dec 01, 2005

Pubmed Data : J Periodontol. 2005 Dec;76(12):2223-9. PMID: 16332233
Article Published Date : Dec 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Apples, Hops
Diseases : Periodontal Diseases, Porphyromonas gingivalis
[+]

Due to its antioxidant, anti-inflammatory and antibacterial effects hop extract might be a treatment option for acne-prone skin.Jan 08, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 Jan 9 ;24(2). Epub 2019 Jan 9. PMID: 30634461
Article Published Date : Jan 08, 2019
Study Type : In Vitro Study
Additional Links
Substances : Hops
Diseases : Acne, Staphylococcus aureus infection
Pharmacological Actions : Anti-Bacterial Agents, Antioxidants, Interleukin-6 Downregulation
Additional Keywords : Plant Extracts
[+]

Evaluating hop extract concentrations found in commercial beer to inhibit Streptococcus mutans biofilm formation.Aug 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Appl Microbiol. 2022 Sep ;133(3):1333-1340. Epub 2022 Jun 5. PMID: 35598180
Article Published Date : Aug 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Hops
Diseases : Steptococcus Mutans Infections
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation, Plant Extracts
[+]

Exploring two types of prenylated bitter compounds from hop plant (Humulus lupulus L.) against α-glucosidase in vitro and in silico.Aug 29, 2021

Pubmed Data : Food Chem. 2021 Aug 30 ;370:130979. Epub 2021 Aug 30. PMID: 34543921
Article Published Date : Aug 29, 2021
Study Type : In Vitro Study
Additional Links
Substances : Hops
Diseases : Hyperglycemia
Pharmacological Actions : Alpha-glucosidase inhibitor , Hypoglycemic Agents
[+]

Glycosyl flavones from Humulus japonicus suppress MMP-1 production via decreasing oxidative stress in UVB irradiated human dermal fibroblasts. Apr 21, 2020

Pubmed Data : BMB Rep. 2020 Apr 22. Epub 2020 Apr 22. PMID: 32317077
Article Published Date : Apr 21, 2020
Study Type : In Vitro Study
Additional Links
Substances : Hops
Diseases : Photooxidative Stress, Ultraviolet Radiation Induced Damage
Pharmacological Actions : Antioxidants, Matrix metalloproteinase-1 (MMP-1) inhibitor, Photoprotective
[+]

Hop bioactive compounds in prevention of nutrition-related noncommunicable diseases.May 27, 2020

Pubmed Data : Crit Rev Food Sci Nutr. 2020 May 28:1-14. Epub 2020 May 28. PMID: 32462886
Article Published Date : May 27, 2020
Study Type : Review
Additional Links
Substances : Hops
Diseases : Cancers: All, Inflammation, Metabolic Diseases, Obesity
Pharmacological Actions : Anti-Inflammatory Agents, Chemopreventive
Additional Keywords : Anti-Obesity Agents
[+]

Hop bitter acids inhibit Tumor Necrosis Facotr alpha (TNF)-induced inflammation. Aug 04, 2009

Pubmed Data : Mol Nutr Food Res. 2009 Aug 4. PMID: 19655312
Article Published Date : Aug 04, 2009
Study Type : In Vitro Study
Additional Links
Substances : Hops
Diseases : Inflammation
Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Hop phytochemicals have potential role in metabolic syndrome prevention and therapy.Oct 18, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2017 Oct 19 ;22(10). Epub 2017 Oct 19. PMID: 29048380
Article Published Date : Oct 18, 2017
Study Type : Review
Additional Links
Substances : Hops, Xanthohumol
Diseases : Metabolic Syndrome X
Pharmacological Actions : Hypolipidemic
Additional Keywords : Anti-Obesity Agents
[+]

Hops contains a compound, demethylxanthohumol, which induces programmed cell death in Burktt lymphoma and acute lymphoblastic leukemia (ALL) cell lines. Oct 01, 2005

Pubmed Data : Chem Biodivers. 2005 Oct;2(10):1331-7. PMID: 17191934
Article Published Date : Oct 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Hops
Diseases : Acute lymphoblastic leukemia (ALL), Burkitt Lymphoma, Lymphoma
Pharmacological Actions : Apoptotic
[+]

Hops contains compounds which exhibit antiviral activity against a series of DNA and RNA viruses. Jan 01, 2004

Pubmed Data : Antiviral Res. 2004 Jan;61(1):57-62. PMID: 14670594
Article Published Date : Jan 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : Hops
Diseases : Cytomegalovirus Infections, Hepatitis C, Herpes family viruses, Rhinovirus Infection
Pharmacological Actions : Antiviral Agents
[+]

Hops contains compounds which inhibit prostate cancer cell growth. Nov 01, 2006

Pubmed Data : Phytomedicine. 2006 Nov;13(9-10):732-4. Epub 2006 May 5. PMID: 16678392
Article Published Date : Nov 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Hops
Diseases : Prostate Cancer
[+]

Hops contains compounds which inhibit the aromatase enzyme and estrogen formation, inducing apoptosis in breast cancer cells. Jun 01, 2007

Pubmed Data : J Steroid Biochem Mol Biol. 2007 Jun-Jul;105(1-5):124-30. Epub 2007 Jul 23. PMID: 17643984
Article Published Date : Jun 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Hops
Diseases : Breast Cancer
Pharmacological Actions : Aromatase Inhibitors
[+]

Hops extracts could be useful in the prevention and treatment of influenza.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:5919237. Epub 2018 Jul 24. PMID: 30140367
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Hops
Diseases : Influenza
Pharmacological Actions : Antioxidants, Antiviral Agents
Additional Keywords : Plant Extracts
[+]

Hops may have use as a chemopreventive agent against prostate cancer.Feb 08, 2007

Pubmed Data : Cancer Lett. 2007 Feb 8;246(1-2):201-9. Epub 2006 Mar 24. PMID: 16563612
Article Published Date : Feb 08, 2007
Study Type : In Vitro Study
Additional Links
Substances : Hops
Diseases : Prostate Cancer
Pharmacological Actions : Apoptotic, Chemopreventive, NF-kappaB Inhibitor
[+]

Hops rich beer contains flavonoids which inhibit extrogen formation in choriocarcinoma-derived cells. Apr 19, 2006

Pubmed Data : J Agric Food Chem. 2006 Apr 19;54(8):2938-43. PMID: 16608212
Article Published Date : Apr 19, 2006
Study Type : In Vitro Study
Additional Links
Substances : Beer, Hops
Diseases : Choriocarcinoma, Trophoblastic Neoplasms, Trophoblastic Tumor
Pharmacological Actions : Aromatase Inhibitors
[+]

Humulone modulation of GABA A receptors and its role in hops sleep-promoting activity.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Neurosci. 2020 ;14:594708. Epub 2020 Oct 14. PMID: 33177986
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Hops
Diseases : Sleep Disorders
Pharmacological Actions : GABA Modulators
[+]

Humulus japonicus stimulates thermogenesis and ameliorates oxidative stress in mouse adipocytes.Jun 30, 2019

Pubmed Data : J Mol Endocrinol. 2019 Jul 1 ;63(1):1-9. PMID: 30978698
Article Published Date : Jun 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Hops
Diseases : Hydrogen Peroxide Induced Toxicity, Obesity, Oxidative Stress
Pharmacological Actions : Antioxidants
Additional Keywords : Risk Reduction
[+]

Inhibitory effect of hop fractions against gram-positive multi-resistant bacteria.May 22, 2018

Pubmed Data : Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2018 May 23. Epub 2018 May 23. PMID: 29790489
Article Published Date : May 22, 2018
Study Type : In Vitro Study
Additional Links
Substances : Hops, Xanthohumol
Diseases : Gram-Positive Bacterial Infections, Infection: Antibiotic Resistant
Pharmacological Actions : Anti-Bacterial Agents
[+]

Phenolic compounds originating from hops have a novel role as antiplatelet agents.Nov 17, 2016

Pubmed Data : Arch Physiol Biochem. 2016 Nov 18:1-7. Epub 2016 Nov 18. PMID: 27855519
Article Published Date : Nov 17, 2016
Study Type : In Vitro Study
Additional Links
Substances : Hops, Xanthohumol
Diseases : Cardiovascular Diseases
Pharmacological Actions : Anti-Platelet
[+]

Purified hop compounds could have use as alternatives for treatment of infections caused by select anaerobic bacteria.Sep 27, 2017

Pubmed Data : APMIS. 2017 Sep 28. Epub 2017 Sep 28. PMID: 28960474
Article Published Date : Sep 27, 2017
Study Type : In Vitro Study
Additional Links
Substances : Hops, Xanthohumol
Diseases : Bacterial Infections, Diarrhea
Pharmacological Actions : Antimicrobial, Gastrointestinal Agents
[+]

Redox and anti-inflammatory properties from hop components in beer-related to neuroprotection.Jun 09, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2021 Jun 10 ;13(6). Epub 2021 Jun 10. PMID: 34200665
Article Published Date : Jun 09, 2021
Study Type : Review
Additional Links
Substances : Hops, Xanthohumol
Diseases : Inflammation: Brain
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Spent hops extract as modulator of the inflammatory response in lipopolysaccharide stimulated RAW 264.7 macrophages.Jan 31, 2020

Pubmed Data : J Physiol Pharmacol. 2020 Feb ;71(1). Epub 2020 Apr 27. PMID: 32350150
Article Published Date : Jan 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Hops
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-6 Downregulation
[+]

The promising ability of Humulus lupulus L. Iso-α-acids vs. diabetes, inflammation, and metabolic syndrome.Feb 10, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2021 Feb 11 ;26(4). Epub 2021 Feb 11. PMID: 33670177
Article Published Date : Feb 10, 2021
Study Type : Review
Additional Links
Substances : Hops
Diseases : Metabolic Syndrome X
Pharmacological Actions : Anti-Inflammatory Agents, Hypoglycemic Agents, Hypolipidemic
[+]

The results showed that hop shoots represent a new source of flavonols.Aug 04, 2017

Pubmed Data : J Pharm Biomed Anal. 2017 Aug 5 ;142:28-34. Epub 2017 Apr 29. PMID: 28494336
Article Published Date : Aug 04, 2017
Study Type : In Vitro Study
Additional Links
Substances : Hops
Pharmacological Actions : Antioxidants
[+]

This study elucidates the molecular mechanisms of the anti-angiogenic activity of xanthohumol.Jul 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2016 Aug 1. Epub 2016 Aug 1. PMID: 27494895
Article Published Date : Jul 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Hops, Xanthohumol
Diseases : Cancers: All
Pharmacological Actions : Angiogenesis Inhibitors, Chemopreventive
[+]

Xanthohumol is a promising α-glucosidase inhibitor, which therefore could be used as functional food to alleviate postprandial hyperglycemia.Jun 17, 2014

Pubmed Data : J Agric Food Chem. 2014 Jun 18 ;62(24):5548-54. Epub 2014 Jun 4. PMID: 24897556
Article Published Date : Jun 17, 2014
Study Type : In Vitro Study
Additional Links
Substances : Hops, Xanthohumol
Diseases : Diabetes Mellitus: Type 2, Hyperglycemia
Pharmacological Actions : Alpha-glucosidase inhibitor , Hypoglycemic Agents
[+]

Xanthohumol, a compound derived from hops and found within beer, exhibits anticancer activity against human breast cancer cell lines. Dec 20, 2005

Pubmed Data : Int J Cancer. 2005 Dec 20;117(6):889-95. PMID: 15986430
Article Published Date : Dec 20, 2005
Study Type : In Vitro Study
Additional Links
Substances : Beer, Hops
Diseases : Breast Cancer, Cancer Metastasis
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Xanthohumol, a compound derived from hops, inhibits hepatic inflammation and fibrosis.Jan 19, 2010

Pubmed Data : Mol Nutr Food Res. 2010 Jan 19. Epub 2010 Jan 19. PMID: 20087858
Article Published Date : Jan 19, 2010
Study Type : In Vitro Study
Additional Links
Substances : Hops
Diseases : Liver Fibrosis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Xanthohumol, a compound derived from hops, inhibits proliferation and migration of liver cancer cells. Feb 01, 2010

Pubmed Data : Int J Oncol. 2010 Feb;36(2):435-41. PMID: 20043079
Article Published Date : Feb 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Hops
Diseases : Liver Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Interleukin-8 downregulation
[+]

Xanthohumol, a compound found within hops, induces programmed cell death in CLL cell lines. Oct 01, 2009

Pubmed Data : Anticancer Res. 2009 Oct;29(10):3797-805. PMID: 19846911
Article Published Date : Oct 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Hops
Diseases : Leukemia: Chronic Lymphocytic Leukemia (CLL)
Pharmacological Actions : Apoptotic

Copyright: aboikis / 123RF Stock Photo

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