Enterodiol

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11 Diseases Researched for Enterodiol

Name	AC	CK
Breast Cancer	6	17
Breast Cancer: Prevention	4	15
Fibroids: Uterine	1	10
Abdominal Obesity (Midsection Fat)	1	2
Adiponectin: Low Levels	1	2
Estrogen Dominance	2	2
Fatty Liver	1	2
Lupus Nephritis	1	2
Prostate Cancer	2	2
Cancers: All	1	1
Colon Cancer	1	1

7 Pharmacological Actions Researched for Enterodiol

Name	AC	CK
Antiproliferative	3	5
Antineoplastic Agents	2	4
Aromatase Inhibitors	3	3
Anti-Adipogenic	1	2
Vascular Endothelial Growth Factor A Inhibitor	1	2
Anticarcinogenic Agents	1	1
Chemopreventive	1	1

Research Articles 12
Cumulative Knowledge Score 19
Overall Research Rating GOOD

View the Evidence:
12 Abstracts with Enterodiol Research

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High dietary intakes of plant lignans and high exposure to enterolignans were associated with reduced risks of ER- and PR-positive postmenopausal breast cancer. Mar 21, 2007

Click here to read the entire abstract

Pubmed Data : J Natl Cancer Inst. 2007 Mar 21;99(6):475-86. PMID: 17374837

Article Published Date : Mar 21, 2007

Study Type : Human Study

Additional Links

Substances : Enterodiol, Enterolactone, Flaxseed, Lignans, phytoestrogens

Diseases : Breast Cancer, Breast Cancer: Prevention

Additional Keywords : Risk Reduction

[+]

There is a modest inverse association between lignan excretion and uterine fibroid risk. Jan 01, 2005

Click here to read the entire abstract

Pubmed Data : Cytotechnology. 2005 Jan;47(1-3):97-105. PMID: 16960173

Article Published Date : Jan 01, 2005

Study Type : Human Study

Additional Links

Substances : Daidzein, Enterodiol, Enterolactone, Equol, Genistein, Isoflavones, Lignans

Diseases : Fibroids: Uterine

[+]

Enterolactone and enterodiol have been shown to negate the tumor-stimulating effect of genistein in a mouse model of breast cancer.Jul 01, 2007

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Pubmed Data : Mol Nutr Food Res. 2007 Jul;51(7):845-56. PMID: 17579892

Article Published Date : Jul 01, 2007

Study Type : Animal Study

Additional Links

Substances : Enterodiol, Enterolactone, Flaxseed, Genistein, Isoflavones, Lignans, phytoestrogens, Soy Protein

Diseases : Breast Cancer, Breast Cancer: Prevention

Pharmacological Actions : Antineoplastic Agents, Antiproliferative

[+]

Flaxseed and its lignans have potent antiestrogenic effects on estrogen receptor-positive breast cancer and may prove to be beneficial in breast cancer prevention strategies in the future.Feb 01, 2007

Click here to read the entire abstract

Pubmed Data : Clin Cancer Res. 2007 Feb 1;13(3):1061-7. PMID: 17289903

Article Published Date : Feb 01, 2007

Study Type : Animal Study

Additional Links

Substances : Enterodiol, Enterolactone, Flaxseed, Lignans

Diseases : Breast Cancer, Breast Cancer: Prevention

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Vascular Endothelial Growth Factor A Inhibitor

[+]

Flaxseed lignan attenuates high-fat diet-induced visceral and liver fat accumulation and induces adiponectin expression in mice.Sep 01, 2008

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Pubmed Data : Br J Nutr. 2008 Sep;100(3):669-76. Epub 2008 Feb 6. PMID: 18252024

Article Published Date : Sep 01, 2008

Study Type : Animal Study

Additional Links

Substances : Enterodiol, Flaxseed, Lignans, Secoisolariciresinol diglucoside (SDG)

Diseases : Abdominal Obesity (Midsection Fat), Adiponectin: Low Levels, Fatty Liver

Pharmacological Actions : Anti-Adipogenic

[+]

The lignan precursor from flaxseed known as secoisolariresinol diglucoside (SDG) may inhibit the progression of lupus nephritis. Jan 01, 2000

Click here to read the entire abstract

Pubmed Data : Lupus. 2000;9(6):429-36. PMID: 10981647

Article Published Date : Jan 01, 2000

Study Type : Animal Study

Additional Links

Substances : Enterodiol, Enterolactone, Flaxseed, Lignans, Secoisolariciresinol diglucoside (SDG)

Diseases : Lupus Nephritis

[+]

Dietary lignans reduce breask cancer risk. Jul 01, 2007

Click here to read the entire abstract

Pubmed Data : Mol Nutr Food Res. 2007 Jul;51(7):857-66. PMID: 17576639

Article Published Date : Jul 01, 2007

Study Type : Review

Additional Links

Substances : Enterodiol, Enterolactone, Lignans

Diseases : Breast Cancer: Prevention

Pharmacological Actions : Chemopreventive

[+]

Lignans and flavonoids act as aromatase inhibitors in human preadipocytes. Aug 01, 1994

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Pubmed Data : J Steroid Biochem Mol Biol. 1994 Aug;50(3-4):205-12. PMID: 8049151

Article Published Date : Aug 01, 1994

Study Type : In Vitro Study

Additional Links

Substances : Enterodiol, Flavonoids, Lignans

Diseases : Breast Cancer, Estrogen Dominance

Pharmacological Actions : Aromatase Inhibitors

[+]

Mammalian lignans and the soy isoflavone genistein inhibit breast cancer via down-regulation of estrogen production. Apr 01, 2005

Click here to read the entire abstract

Pubmed Data : J Steroid Biochem Mol Biol. 2005 Apr;94(5):461-7. Epub 2005 Mar 16. PMID: 15876411

Article Published Date : Apr 01, 2005

Study Type : In Vitro Study

Additional Links

Substances : Enterodiol, Enterolactone, Genistein, Lignans

Diseases : Breast Cancer, Estrogen Dominance

Pharmacological Actions : Aromatase Inhibitors

[+]

Mammalian lignans formed as a byproduct of flaxseed consumption inhibit prostate cancer cell growth. Nov 01, 2001

Click here to read the entire abstract

Pubmed Data : Anticancer Res. 2001 Nov-Dec;21(6A):3995-9. PMID: 11911282

Article Published Date : Nov 01, 2001

Study Type : In Vitro Study

Additional Links

Substances : Enterodiol, Enterolactone, Flaxseed, Lignans

Diseases : Prostate Cancer

Pharmacological Actions : Anticarcinogenic Agents

[+]

Mammalian lignans inhibit the growth of estrogen-independent human colon tumor cells.May 01, 1998

Click here to read the entire abstract

Pubmed Data : Anticancer Res. 1998 May-Jun;18(3A):1405-8. PMID: 9673348

Article Published Date : May 01, 1998

Study Type : In Vitro Study

Additional Links

Substances : Enterodiol, Enterolactone, Flaxseed, Lignans

Diseases : Colon Cancer

Pharmacological Actions : Antiproliferative

[+]

The mammalian phytoestrogens enterodiol and enterolactone may protect against breast and prostate cancer through hormone modulating activities.Sep 25, 2002

Click here to read the entire abstract

Pubmed Data : J Chromatogr B Analyt Technol Biomed Life Sci. 2002 Sep 25;777(1-2):289-309. PMID: 12270221

Article Published Date : Sep 25, 2002

Study Type : Review

Additional Links

Substances : Enterodiol, Enterolactone, Flaxseed, Lignans, phytoestrogens, Secoisolariciresinol diglucoside (SDG)

Diseases : Breast Cancer, Cancers: All, Prostate Cancer

Pharmacological Actions : Aromatase Inhibitors

Research Articles 12
Cumulative Knowledge Score 19
Overall Research Rating GOOD

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Focus Your Research

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View the Evidence: 12 Abstracts with Enterodiol Research

Limited to Members Only

Currently Available Sorting Options

High dietary intakes of plant lignans and high exposure to enterolignans were associated with reduced risks of ER- and PR-positive postmenopausal breast cancer. Mar 21, 2007

There is a modest inverse association between lignan excretion and uterine fibroid risk. Jan 01, 2005

Enterolactone and enterodiol have been shown to negate the tumor-stimulating effect of genistein in a mouse model of breast cancer.Jul 01, 2007

Flaxseed and its lignans have potent antiestrogenic effects on estrogen receptor-positive breast cancer and may prove to be beneficial in breast cancer prevention strategies in the future.Feb 01, 2007

Flaxseed lignan attenuates high-fat diet-induced visceral and liver fat accumulation and induces adiponectin expression in mice.Sep 01, 2008

The lignan precursor from flaxseed known as secoisolariresinol diglucoside (SDG) may inhibit the progression of lupus nephritis. Jan 01, 2000

Dietary lignans reduce breask cancer risk. Jul 01, 2007

Lignans and flavonoids act as aromatase inhibitors in human preadipocytes. Aug 01, 1994

Mammalian lignans and the soy isoflavone genistein inhibit breast cancer via down-regulation of estrogen production. Apr 01, 2005

Mammalian lignans formed as a byproduct of flaxseed consumption inhibit prostate cancer cell growth. Nov 01, 2001

Mammalian lignans inhibit the growth of estrogen-independent human colon tumor cells.May 01, 1998

The mammalian phytoestrogens enterodiol and enterolactone may protect against breast and prostate cancer through hormone modulating activities.Sep 25, 2002

Enterodiol Related Articles

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Enterodiol

View the Evidence:
12 Abstracts with Enterodiol Research