Dragon Fruit

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32 Diseases Researched for Dragon Fruit
NameACCKFocus
Diabetes Mellitus: Type 2121Locked
Endothelial Dysfunction110Locked
Hypertension110Locked
Obesity510Locked
High Fat Diet36Locked
Insulin Resistance36Locked
Metabolic Syndrome X24Locked
Anxiety12Locked
Asthma12Locked
Athletic Performance: Recovery 12Locked
Brain: Oxidative Stress12Locked
Breast Cancer22Locked
Cardiovascular Diseases12Locked
Chemotherapy-Induced Kidney Damage12Locked
Chemotherapy-Induced Toxicity: Cisplatin12Locked
Copper Toxicity12Locked
Drug-Induced Toxicity: Indomethacin12Locked
Fatty Liver12Locked
Gastric Ulcer12Locked
Hepatic Steatosis12Locked
Inflammation12Locked
Liver Steatosis12Locked
Metabolic Diseases12Locked
Nonalcoholic fatty liver disease (NAFLD)12Locked
Oxidative Stress12Locked
Breast Cancer: Triple Negative 11Locked
Colon Cancer11Locked
Colorectal Cancer11Locked
Influenza A11Locked
Prostate Cancer11Locked
Pseudomonas aeruginosa11Locked
Staphylococcus aureus infection11Locked
22 Pharmacological Actions Researched for Dragon Fruit
NameACCKFocus
Hypoglycemic Agents223Locked
Gastrointestinal Agents314Locked
Antioxidants813Locked
Gastroprotective110Locked
Vasoprotective110Locked
Hepatoprotective36Locked
Apoptotic33Locked
Anti-Anxiety Agents12Locked
Anti-Inflammatory Agents12Locked
Anti-Ulcer Agents12Locked
Chemopreventive22Locked
Chemoprotective Agents12Locked
Fibroblast growth factor 21 upregulation12Locked
Hypolipidemic12Locked
Neuroprotective Agents12Locked
Renoprotective12Locked
Anti-Bacterial Agents11Locked
Antiproliferative 11Locked
Antiviral Agents11Locked
Bcl-2 protein down-regulation11Locked
Cell cycle arrest11Locked
Immunomodulatory11Locked

View the Evidence:
25 Abstracts with Dragon Fruit Research

[+]

Effect of dragon fruit on glycemic control in prediabetes and type 2 diabetes.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2017 ;12(9):e0184577. Epub 2017 Sep 8. PMID: 28886195
Article Published Date : Dec 31, 2016
Study Type : Meta Analysis, Review
Additional Links
Substances : Dragon Fruit
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents
Additional Keywords : Plant Extracts
[+]

Betalain-rich dragon fruit (pitaya) consumption improves vascular function in men and women.Dec 31, 2021

Pubmed Data : Am J Clin Nutr. 2022 05 1 ;115(5):1418-1431. PMID: 35265960
Article Published Date : Dec 31, 2021
Study Type : Human Study
Additional Links
Substances : Dragon Fruit
Diseases : Endothelial Dysfunction, Hypertension
Pharmacological Actions : Vasoprotective
[+]

Effects of dragon fruit oligosaccharides on immunity, gut microbiome, and their metabolites in healthy adults.Apr 30, 2023

Pubmed Data : Food Res Int. 2023 May ;167:112657. Epub 2023 Mar 1. PMID: 37087207
Article Published Date : Apr 30, 2023
Study Type : Human Study
Additional Links
Substances : Dragon Fruit, Oligosaccharides
Pharmacological Actions : Gastrointestinal Agents, Gastroprotective
[+]

Exploring the effects of whole food-based dragon fruit on metabolic disorders in high-fat diet.Oct 02, 2024

Pubmed Data : Mol Nutr Food Res. 2024 Oct 3:e2400604. Epub 2024 Oct 3. PMID: 39363653
Article Published Date : Oct 02, 2024
Study Type : Animal Study
Additional Links
Substances : Dragon Fruit
Diseases : Metabolic Diseases
Pharmacological Actions : Gastrointestinal Agents, Hypoglycemic Agents, Hypolipidemic
[+]

Fruit extract of red pitaya (Hylocereus undatus) prevents and reverses stress-induced impairments in the cholinergic and antioxidant systems.Dec 31, 2021

Pubmed Data : J Food Biochem. 2022 04 ;46(4):e13981. Epub 2021 Oct 26. PMID: 34698395
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Dragon Fruit
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
[+]

Hylocereus undatus flower extract suppresses OVA-induced allergic asthma.Aug 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2022 Sep ;153:113476. Epub 2022 Jul 26. PMID: 35977054
Article Published Date : Aug 31, 2022
Study Type : Animal Study
Additional Links
Substances : Dragon Fruit
Diseases : Asthma, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents
[+]

Neuroprotective and antioxidant effects of pitaya fruit on Cu-induced stress in adult zebrafish.Mar 28, 2022

Pubmed Data : J Food Biochem. 2022 Mar 29:e14147. Epub 2022 Mar 29. PMID: 35347737
Article Published Date : Mar 28, 2022
Study Type : Animal Study
Additional Links
Substances : Dragon Fruit
Diseases : Brain: Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Pitaya fruit extract ameliorates the healthspan on copper-induced toxicity of Caenorhabditis elegans.Dec 31, 2021

Pubmed Data : J Food Biochem. 2022 03 ;46(3):e14050. Epub 2022 Jan 3. PMID: 34981523
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Dragon Fruit
Diseases : Copper Toxicity
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
[+]

Pitaya peel has the potential as a treatment for anxiety disorders.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Res Int. 2020 Jan ;127:108701. Epub 2019 Oct 31. PMID: 31882110
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Dragon Fruit
Diseases : Anxiety
Pharmacological Actions : Anti-Anxiety Agents
[+]

Purified betacyanins from Hylocereus undatus peel ameliorate obesity and insulin resistance in high-fat-diet-fed mice.Jan 12, 2016

Pubmed Data : J Agric Food Chem. 2016 Jan 13 ;64(1):236-44. Epub 2015 Dec 24. PMID: 26653843
Article Published Date : Jan 12, 2016
Study Type : Animal Study
Additional Links
Substances : Dragon Fruit
Diseases : High Fat Diet, Insulin Resistance, Obesity
Additional Keywords : Anti-Obesity Agents, Gene Expression Regulation, Plant Extracts
Problem Substances : Insulin
[+]

Red dragon fruit extract has potential in lowering lactic acid level and CK activity in male rats receiving heavy physical exercise.Jul 29, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Open Access Maced J Med Sci. 2019 Jul 30 ;7(14):2232-2235. Epub 2019 Jul 20. PMID: 31592070
Article Published Date : Jul 29, 2019
Study Type : Animal Study
Additional Links
Substances : Dragon Fruit
Diseases : Athletic Performance: Recovery
Therapeutic Actions : Exercise
[+]

Red pitaya betacyanins protect from diet-induced obesity and its related metabolic disorders.Jul 31, 2016

Pubmed Data : J Gastroenterol Hepatol. 2016 Aug ;31(8):1462-9. PMID: 26699443
Article Published Date : Jul 31, 2016
Study Type : Animal Study
Additional Links
Substances : Dragon Fruit
Diseases : High Fat Diet, Insulin Resistance, Liver Steatosis, Nonalcoholic fatty liver disease (NAFLD), Obesity
Pharmacological Actions : Hepatoprotective
Additional Keywords : Microbiota
[+]

Red pitaya had beneficial effects on energy balance homeostasis by modulating the anorectic, orexigenic and energy expenditure related genes.Jul 25, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2016 Jul 26 ;16:243. Epub 2016 Jul 26. PMID: 27456968
Article Published Date : Jul 25, 2016
Study Type : Animal Study
Additional Links
Substances : Dragon Fruit
Diseases : High Fat Diet, Metabolic Syndrome X, Obesity
Additional Keywords : Anti-Obesity Agents, Gene Expression Regulation
[+]

Red pitaya juice may provide protection against liver damage and may reduce the stiffness of the heart.Jun 11, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2014 Jun 12 ;14:189. Epub 2014 Jun 12. PMID: 24919841
Article Published Date : Jun 11, 2014
Study Type : Animal Study
Additional Links
Substances : Dragon Fruit
Diseases : Cardiovascular Diseases, Fatty Liver, Metabolic Syndrome X, Obesity
Pharmacological Actions : Hepatoprotective
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Stenocereus huastecorum-fruit juice concentrate protects against cisplatin-induced nephrotoxicity.Sep 30, 2022

Pubmed Data : Food Res Int. 2022 Oct ;160:111337. Epub 2022 May 9. PMID: 36076365
Article Published Date : Sep 30, 2022
Study Type : Animal Study
Additional Links
Substances : Dragon Fruit
Diseases : Chemotherapy-Induced Kidney Damage, Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions : Antioxidants, Chemoprotective Agents, Renoprotective
[+]

The effects of dragon fruit extract on indomethacin-induced stomach ulcer.Aug 31, 2022

Pubmed Data : J Food Biochem. 2022 Sep ;46(9):e14274. Epub 2022 Jun 18. PMID: 35716002
Article Published Date : Aug 31, 2022
Study Type : Animal Study
Additional Links
Substances : Dragon Fruit
Diseases : Drug-Induced Toxicity: Indomethacin, Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents, Antioxidants
Problem Substances : Indomethacin, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

White pitaya juice protected from diet-induced hepatic steatosis and insulin resistance.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2016 ;11(2):e0149670. Epub 2016 Feb 25. PMID: 26914024
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Dragon Fruit
Diseases : Hepatic Steatosis, Insulin Resistance, Obesity
Pharmacological Actions : Fibroblast growth factor 21 upregulation, Hepatoprotective
Additional Keywords : Gene Expression Regulation, Plant Extracts
[+]

Pitaya may have a protective effect against breast cancer.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2017 ;2017:7865073. Epub 2017 Jul 6. PMID: 28761624
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Dragon Fruit
Diseases : Breast Cancer, Breast Cancer: Triple Negative
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Chemopreventive
Additional Keywords : BRCA Gene, Gene Expression Regulation
[+]

Betacyanins from red pitahaya exhibit antiviral response against influenza A virus.Jun 29, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Heliyon. 2024 Jun 30 ;10(12):e33049. Epub 2024 Jun 15. PMID: 39021953
Article Published Date : Jun 29, 2024
Study Type : In Vitro Study
Additional Links
Substances : Dragon Fruit
Diseases : Influenza A
Pharmacological Actions : Antiviral Agents
[+]

Biofilm inhibiting activity of betacyanins from red pitahaya.Dec 31, 2018

Pubmed Data : J Appl Microbiol. 2019 Jan ;126(1):68-78. Epub 2018 Oct 17. PMID: 30153380
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Dragon Fruit, Spinach
Diseases : Pseudomonas aeruginosa, Staphylococcus aureus infection
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation, Plant Extracts
[+]

Dragon fruits as a reservoir of natural polyphenolics with chemopreventive properties.Apr 08, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2021 Apr 9 ;26(8). Epub 2021 Apr 9. PMID: 33918584
Article Published Date : Apr 08, 2021
Study Type : In Vitro Study
Additional Links
Substances : Dragon Fruit, Polyphenols
Diseases : Colon Cancer, Prostate Cancer
Pharmacological Actions : Antioxidants, Apoptotic, Chemopreventive
[+]

Fresh extracts from red pitaya have strong antioxidant activity.Jun 30, 2016

Pubmed Data : Food Chem. 2016 Jul 1 ;202:70-80. Epub 2016 Jan 28. PMID: 26920267
Article Published Date : Jun 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Dragon Fruit
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
[+]

Peels as well as pulp of pitaya could beneficially help in the food industry.Aug 26, 2014

Pubmed Data : J Agric Food Chem. 2014 Aug 27 ;62(34):8764-71. Epub 2014 Aug 14. PMID: 25101804
Article Published Date : Aug 26, 2014
Study Type : In Vitro Study
Additional Links
Substances : Dragon Fruit
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
[+]

Potential apoptotic activities of Hylocereus undatus peel and pulp extracts in MCF-7 and Caco-2 cancer cell lines.Aug 23, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Plants (Basel). 2022 Aug 24 ;11(17). Epub 2022 Aug 24. PMID: 36079573
Article Published Date : Aug 23, 2022
Study Type : In Vitro Study
Additional Links
Substances : Dragon Fruit
Diseases : Breast Cancer, Colorectal Cancer
Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation
[+]

Terpenoid-lupeol of red dragon fruit and its immunomodulatory activity.Feb 29, 2020

Pubmed Data : Pak J Pharm Sci. 2020 Mar ;33(2):505-510. PMID: 32276891
Article Published Date : Feb 29, 2020
Study Type : In Vitro Study
Additional Links
Substances : Dragon Fruit
Pharmacological Actions : Immunomodulatory

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