Cocoa

Name	AC	CK
Cardiovascular Diseases	23	248
Hypertension	16	165
Endothelial Dysfunction	12	140
Diabetes Mellitus: Type 2	16	138
Oxidative Stress	14	113
Obesity	10	89
Inflammation	13	83
Coronary Artery Disease	5	70
Heart Failure	5	70
Stroke	5	61
Arterial Hardening: Elasticity	4	60
Insulin Resistance	5	54
Cognitive Decline/Dysfunction	7	53
Cardiovascular Disease: Prevention	3	40
Insulin: Elevated	1	40
Aging	5	36
Metabolic Syndrome X	4	32
Cardiac Mortality	3	30
Hemodialysis	2	30
Pre-Eclampsia	2	30
Nonalcoholic fatty liver disease (NAFLD)	3	23
Depression	3	21
Glaucoma	2	21
Blood Sugar Problems	1	20
Cardiovascular Disease	1	20
Cholesterol: LDL/HDL ratio	2	20
DNA damage	1	20
Diabetes Mellitus: Type 1	2	20
Fatigue	2	20
Gestational Diabetes	2	20
HDL: Low	2	20
Heart Disease: Ischemic	1	20
Low Testosterone	2	20
Myocardial Infarction	1	20
Myocardial Infarction: Prevention	1	20
Ocular Hypertension	1	20
Overweight	2	20
Peripheral Arterial Disease	2	20
Stress	2	20
Wrinkles	4	18
Memory Disorders	3	14
Athletic Performance	2	12
Ultraviolet Radiation Induced Damage	2	12
Diabetes Mellitus: Type 2: Prevention	2	11
Heart Attack	2	11
Steptococcus Mutans Infections	2	11
Abdominal Obesity (Midsection Fat)	1	10
All-Cause Mortality	1	10
Allergies	1	10
Arteriosclerosis	1	10
Athletic Performance: Recovery	1	10
Autism Spectrum Disorders	1	10
C-Reactive Protein	1	10
Calcification: Arterial	1	10
Catecholamines: Elevated	1	10
Cholesterol: Oxidation	1	10
Chronic Pain	1	10
Cirrhosis	1	10
Cortisol: High	1	10
Diabetes: Cardiovascular Illness	1	10
Diabetes: Cognitive Dysfunction	1	10
Diabetes: Oxidative Stress	1	10
Diabetes: Vascular Dysfunction	1	10
Dysbiosis	1	10
Exercise-Induced Tissue Damage	1	10
Fibromyalgia	1	10
HIV Infections	1	10
Hypertension: Portal	1	10
Influenza A	1	10
Influenza B	1	10
Lipid Peroxidation	1	10
Memory Disorders: Sleep Deprivation Induced	1	10
Mood Disorders	1	10
Multiple Sclerosis	1	10
Normal weight obese (NWO) syndrome	1	10
Postmenopausal Disorders	1	10
Postmenopausal Disorders: Weight Gain/Obesity	1	10
Skin Diseases: Photo-Aging	1	10
Sunburn	1	10
Hyperlipidemia	4	7
Alzheimer's Disease	4	5
Atherosclerosis	3	5
Parkinson's Disease	4	5
Cancers: All	4	4
Colorectal Cancer: Prevention	2	4
Heavy Metal Toxicity	1	4
High Fat Diet	2	4
Aging Skin	2	3
Aging: Brain	2	3
Autoimmune Diseases	2	3
Colorectal Cancer	2	3
Lung Cancer	2	3
Lymphoma	2	3
Acrylamide-induced toxicity	1	2
Androgen-Induced Diseases	1	2
Asthma	1	2
Colitis	1	2
Constipation	1	2
Diabetic Nephropathy	1	2
Dysbiosis: Bifidobacteria Deficiency	1	2
Dyslipidemias	1	2
High Cholesterol	1	2
High Fructose Diet	1	2
High Sugar Diet	2	2
Hypoxia	1	2
Inflammatory Bowel Diseases	1	2
Kidney Damage: Chemically-Induced	1	2
Lipopolysaccharide-Induced Toxicity	2	2
Liver Steatosis	1	2
Low Immune Function: Exercise-Induced	1	2
Myocardial Fibrosis	1	2
Myocarditis: Autoimmune	1	2
Oral Cancer	1	2
Osteoporosis	1	2
Periodontitis	1	2
Prostate Cancer	1	2
Prostatic Hyperplasia: Benign	1	2
Testosterone-Induced	1	2
Triglycerides: Elevated	1	2
Vitamin D Deficiency	1	2
Advanced Glycation End products (AGE)	1	1
Air Pollution Linked Toxicity	1	1
Alopecia	1	1
Arthritis	1	1
Atrial Fibrillation	1	1
Bacillus subtilis infections	1	1
Breast Cancer	1	1
Cardiac Arrhythmias	1	1
Cardiac Hypertrophy	1	1
Coronavirus Infection	1	1
Endocannabinoid System	1	1
Enterococcus Infections	1	1
Fungal Infection	1	1
Glyphosate Toxicity	1	1
Klebsiella Infections	1	1
Lung Cancer: Prevention	1	1
Metabolic Diseases	1	1
Neurodegenerative Diseases	1	1
Ovarian Cancer	1	1
Periodontal Diseases	1	1
Porphyromonas gingivalis	1	1
Prediabetes	1	1
Pseudomonas aeruginosa	1	1
Salmonella Infections	1	1
Staphylococcus aureus infection	1	1
Staphylococcus epidermidis	1	1
Sugar (Sucrose) Toxicity	1	1
Cataract	1	0
Diabetes: Cataract	1	0

Name	AC	CK
Cardioprotective	24	221
Antioxidants	35	205
Anti-Inflammatory Agents	22	117
Antihypertensive Agents	14	99
Neuroprotective Agents	17	93
Hypoglycemic Agents	7	76
Hypolipidemic	9	51
Hypotensive	2	50
Anticholesteremic Agents	3	42
Vasodilator Agents	4	31
Tumor Necrosis Factor (TNF) Alpha Inhibitor	5	25
Cardiovascular Agents	1	20
Genoprotective	1	20
Telomere Protective	2	20
Interleukin-6 Downregulation	4	15
Nrf2 activation	3	13
Photoprotective	3	13
Antidepressive Agents	2	11
Antimicrobial	2	11
Antiviral Agents	2	11
Analgesics	1	10
Anti-Adipogenic	1	10
Anti-Allergic Agents	1	10
Antinoceceptive	1	10
Appetite Depressants	1	10
Cardiotonic Agents	1	10
Gastrointestinal Agents	1	10
Gastroprotective	1	10
Heme oxygenase-1 up-regulation	1	10
Immunostimulatory	1	10
Interleukin-10 upregulation	1	10
MicroRNA modulator	1	10
Vasoprotective	1	10
Anti-Apoptotic	4	7
Chemopreventive	4	7
Apoptotic	5	6
Immunomodulatory	4	6
Hepatoprotective	3	5
Antiproliferative	4	4
Brain-derived neurotrophic factor modulator	2	4
Chelating Agents	1	4
Renoprotective	2	4
Anti-Asthmatic Agents	1	2
Anti-Fibrotic	1	2
Anticarcinogenic Agents	1	2
Cyclooxygenase 2 Inhibitors	1	2
Laxative	1	2
Osteoprotective	1	2
STAT3 Inhibitor	1	2
Tumor Suppressor Protein p53 Upregulation	1	2
5-Lipoxygenase Inhibitor	1	1
Angiogenesis Inhibitors	1	1
Anti-Bacterial Agents	1	1
Anti-Glycation Agents	1	1
Antifungal Agents	1	1
Cell cycle arrest	1	1
Cytotoxic	1	1
Endocannabinoid Modulator	1	1
Enzyme Inhibitors	1	1
Glucose Uptake Optimization	1	1
Insulin-releasing	1	1
Matrix metalloproteinase-2 (MMP-2) inhibitor	1	1
NF-kappaB Inhibitor	1	1
Nitric Oxide Inhibitor	1	1
Postaglandin PGE2 downregulation	1	1
Tyrosinase Inhibition	1	1

[+]

Dark chocolate cocoa may improve systemic oxidative status and inflammation in adults.Aug 31, 2024

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : BMJ. 2011 ;343:d4488. Epub 2011 Aug 26. PMID: 21875885

Article Published Date : Jan 01, 2011

Study Type : Meta Analysis

Additional Links

Substances : Chocolate

Diseases : Blood Sugar Problems, Cardiovascular Diseases, Coronary Artery Disease, Diabetes Mellitus: Type 2, Metabolic Syndrome X, Stroke

Pharmacological Actions : Cardioprotective

[+]

Chocolate consumption is associated with lower risk of myocardial infarction and ischaemic heart disease.Jun 30, 2016

Click here to read the entire abstract

Pubmed Data : Heart. 2016 Jul 1 ;102(13):1017-22. Epub 2016 Mar 2. PMID: 26936339

Article Published Date : Jun 30, 2016

Study Type : Human Study, Meta Analysis

Additional Links

Substances : Chocolate

Diseases : Heart Disease: Ischemic, Myocardial Infarction, Myocardial Infarction: Prevention

Pharmacological Actions : Cardioprotective

Additional Keywords : Risk Reduction

[+]

Chocolate consumption may be associated with reduced risk of cardiovascular disease.Jul 29, 2018

Click here to read the entire abstract

Pubmed Data : Heart. 2018 Jul 30. Epub 2018 Jul 30. PMID: 30061161

Article Published Date : Jul 29, 2018

Study Type : Meta Analysis

Additional Links

Substances : Chocolate

Diseases : Cardiovascular Diseases

Additional Keywords : Risk Reduction

[+]

Chocolate could be a useful aid for recovery from exercise.Jun 18, 2018

Click here to read the entire abstract

Pubmed Data : Eur J Clin Nutr. 2018 Jun 19. Epub 2018 Jun 19. PMID: 29921963

Article Published Date : Jun 18, 2018

Study Type : Meta Analysis, Review

Additional Links

Substances : Chocolate

Therapeutic Actions : Exercise

[+]

Cocoa and dark chocolate supplementation reduced body weight, body mass index and waist circumference.Mar 18, 2018

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2017 Dec 11 ;9(12). Epub 2017 Dec 11. PMID: 29232891

Article Published Date : Dec 10, 2017

Study Type : Meta Analysis, Review

Additional Links

Substances : Cocoa, Polyphenols, Pomegranate, Turmeric

Diseases : Cardiovascular Diseases, Hemodialysis

Pharmacological Actions : Antihypertensive Agents, Cardioprotective

Additional Keywords : Risk Reduction

[+]

A proprietary blend of standardized Punica granatum fruit rind and Theobroma cocoa seed extracts mitigates aging males' symptoms.Dec 31, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Med Sci. 2022 ;19(8):1290-1299. Epub 2022 Jul 11. PMID: 35928723

Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Chocolate consumption was associated with a significant lower risk of stroke in women.Mar 03, 2017

Click here to read the entire abstract

Pubmed Data : Atherosclerosis. 2017 Mar 4 ;260:8-12. Epub 2017 Mar 4. PMID: 28324761

Article Published Date : Mar 03, 2017

Study Type : Human Study

Additional Links

Substances : Chocolate

Diseases : Stroke

Additional Keywords : Risk Reduction

[+]

Chocolate enriched by extra virgin olive oil improves endothelial function and oxidative stress in patients with diabetes.Apr 06, 2021

Click here to read the entire abstract

Pubmed Data : Nutrition. 2021 Apr 7 ;90:111270. Epub 2021 Apr 7. PMID: 34010747

Click here to read the entire abstract

Pubmed Data : J Alzheimers Dis. 2016 May 6. Epub 2016 May 6. PMID: 27163823

Pubmed Data : Breast Cancer Res Treat. 2009 Sep;117(1):111-9. Epub 2008 Oct 18. PMID: 16794456

Article Published Date : Sep 01, 2009

Study Type : Human Study

Additional Links

Substances : Cocoa

Diseases : Endothelial Dysfunction, Postmenopausal Disorders

[+]

Chronic supplementation with dark chocolate as a rich source of polyphenols positively modulates exercise-induced intestinal damage in elite football athletes.Sep 27, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2023 Sep 28 ;15(19). Epub 2023 Sep 28. PMID: 37836487

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Food Funct. 2022 Oct 17 ;13(20):10439-10448. Epub 2022 Oct 17. PMID: 36164983

Article Published Date : Oct 16, 2022

Study Type : Human Study

Additional Links

Substances : Cocoa, Polyphenols

Diseases : Diabetes Mellitus: Type 2, Endothelial Dysfunction

Pharmacological Actions : Vasodilator Agents

[+]

Cocoa flavanol intake has the potential to reduce the 10-year risk of CV morbidity and mortality even in this healthy cohort by 20–30 % and 30–40 % respectively.Sep 08, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Br J Nutr. 2015 Sep 9:1-10. Epub 2015 Sep 9. PMID: 26348767

Click here to read the entire abstract

Pubmed Data : J Sci Food Agric. 2016 Mar ;96(4):1150-8. Epub 2015 Apr 27. PMID: 25847473

Article Published Date : Feb 29, 2016

Study Type : Animal Study, Human Study, In Vitro Study

Additional Links

Substances : Cocoa

Diseases : Influenza A, Influenza B

Pharmacological Actions : Antiviral Agents, Immunostimulatory

Additional Keywords : Dose Response

[+]

Effects of dark chocolate intake on brain electrical oscillations in healthy people.Nov 07, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Foods. 2018 Nov 8 ;7(11). Epub 2018 Nov 8. PMID: 30413065

Article Published Date : Nov 07, 2018

Study Type : Human Study

Additional Links

Substances : Chocolate

[+]

Flavanol-rich chocolate acutely improves vascular function in patients with congestive heart failure.Aug 31, 2012

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Eur Heart J. 2012 Sep ;33(17):2172-80. Epub 2011 Dec 15. PMID: 22173910

Article Published Date : Aug 31, 2012

Study Type : Human Study

Additional Links

Substances : Chocolate

Diseases : Endothelial Dysfunction, Heart Failure, Oxidative Stress

Pharmacological Actions : Cardioprotective

[+]

Flavanol-rich chocolate counteracted vascular impairment after sleep deprivation and restored working memory performance.Jun 30, 2016

Pubmed Data : Nutrition. 2018 Oct 5 ;60:53-58. Epub 2018 Oct 5. PMID: 30529883

Article Published Date : Oct 04, 2018

Study Type : Human Study

Additional Links

Substances : Chocolate, Cocoa

Diseases : Arterial Hardening: Elasticity

[+]

Habitual cocoa intake efficiently reduces blood pressure and improves the formation of vasodilative nitric oxide. Jul 04, 2007

Intake of chocolate before a painful stimulus had a pain-reducing effect no matter the cocoa concentration.Dec 31, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2023 ;18(5):e0284769. Epub 2023 May 24. PMID: 37224109

Article Published Date : Dec 31, 2022

Study Type : Human Study

Additional Links

Substances : Cocoa

Diseases : Chronic Pain

Pharmacological Actions : Analgesics, Antinoceceptive

[+]

Intake of cocoa extract within an energy-restricted diet revealed a higher reduction of postprandial AUC of SBP when compared to control group.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Food Nutr Res. 2016 ;60:30449. Epub 2016 Mar 31. PMID: 27037002

Article Published Date : Dec 31, 2015

Study Type : Human Study

Additional Links

Substances : Cocoa

Diseases : Hypertension

Pharmacological Actions : Antihypertensive Agents

Additional Keywords : Plant Extracts

[+]

Mindful chocolate consumption appears to increase positive mood.Dec 31, 2016

Click here to read the entire abstract

Pubmed Data : Appetite. 2017 Jan 1 ;108:21-27. Epub 2016 Sep 15. PMID: 27642035

Article Published Date : Dec 31, 2016

Study Type : Human Study

Additional Links

Substances : Chocolate

Additional Keywords : Food-Mood Correlation

[+]

Pubmed Data : Integr Med (Encinitas). 2018 Oct ;17(5):31-38. PMID: 31043917

Article Published Date : Sep 30, 2018

Study Type : Human Study

Additional Links

Substances : Chocolate

Diseases : Autism Spectrum Disorders

Pharmacological Actions : Antioxidants

Additional Keywords : Significant Treatment Outcome

[+]

Solid dark chocolate and liquid cocoa improve endothelial function and lower blood pressure in overweight adults. Jul 01, 2008

Click here to read the entire abstract

Pubmed Data : Am J Clin Nutr. 2008 Jul;88(1):58-63. PMID: 18614724

Article Published Date : Jul 01, 2008

Study Type : Human Study

Additional Links

Substances : Cocoa

Diseases : Endothelial Dysfunction, Hypertension

[+]

Sugar-free dark chocolate consumption results in lower blood glucose in adults with diabetes.Dec 31, 2021

Pubmed Data : BMC Complement Altern Med. 2010;10:61. Epub 2010 Oct 20. PMID: 20961452

Article Published Date : Jan 01, 2010

Study Type : Animal Study

Additional Links

Substances : Cocoa

Diseases : Lymphoma

[+]

CCGG stimulated lipid metabolism in HED-induced obese rats, which is attributable to fat mobilization from adipose tissue.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : J Nutr Biochem. 2021 06 ;92:108618. Epub 2021 Mar 9. PMID: 33711421

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Substances : Cocoa

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Antioxidants, Hepatoprotective

[+]

Combinations of pomegranate with each of VIN, propolis, or cocoa have a promising disease-modifying antiparkinsonian therapy.Aug 11, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Mol Neurobiol. 2021 Oct 18. Epub 2021 Oct 18. PMID: 34661852

Article Published Date : Oct 17, 2021

Study Type : Animal Study

Additional Links

Substances : Chocolate

Diseases : Acrylamide-induced toxicity

Pharmacological Actions : Neuroprotective Agents

Problem Substances : Acrylamide

[+]

Dietary CCGG supplementation may exert potential effects on ameliorating hyperlipidaemia, insulin resistance, liver steatosis and related inflammation.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomolecules. 2022 Dec 17 ;12(12). Epub 2022 Dec 17. PMID: 36551321

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2019 Apr 20 ;11(4). Epub 2019 Apr 20. PMID: 31010016

Article Published Date : Apr 19, 2019

Study Type : Animal Study

Additional Links

Substances : Cocoa

Diseases : Memory Disorders

Pharmacological Actions : Brain-derived neurotrophic factor modulator

[+]

Theobromine is responsible for the effects of cocoa on the antibody immune status of rats.Feb 28, 2018

Click here to read the entire abstract

Pubmed Data : J Nutr. 2018 Mar 1 ;148(3):464-471. PMID: 29546302

Article Published Date : Feb 28, 2018

Study Type : Animal Study

Additional Links

Substances : Cocoa

Pharmacological Actions : Immunomodulatory

[+]

These results demonstrate that cocoa-carob blend strongly prevents the cardiac remodelling and dysfunction observed in diabetic animals.Feb 20, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Crit Rev Food Sci Nutr. 2018 Jul 11:1-19. Epub 2018 Jul 11. PMID: 29993262

Click here to read the entire abstract

Pubmed Data : Med Hypotheses. 2006;67(4):682-97. Epub 2006 Jul 7. PMID: 16828233

Article Published Date : Jan 01, 2006

Study Type : Commentary

Additional Links

Substances : Chromium, Cinnamon, Cocoa, DHA (Docosahexaenoic Acid), Fish Oil, Folic Acid , Genistein, Hops, Policosanol, Sesame Seeds, Vitamin D

Diseases : Alzheimer's Disease, Neurodegenerative Diseases

[+]

Animal experimentation and cocoa interventions in humans support the anti-inflammatory effect of cocoa compounds.Apr 08, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Curr Aging Sci. 2022 Aug 19. Epub 2022 Aug 19. PMID: 35993474

Article Published Date : Aug 18, 2022

Study Type : Review

Additional Links

Substances : Cocoa, Flavonoids

Diseases : Aging: Brain , Alzheimer's Disease, Parkinson's Disease

Pharmacological Actions : Neuroprotective Agents

[+]

[+]

[+]

Physiological and growth responses of cacao to glyphosate exposure.Dec 31, 2022

Click here to read the entire abstract

Pubmed Data : J Environ Sci Health B. 2023 ;58(2):91-99. Epub 2023 Jan 27. PMID: 36708092

Article Published Date : Dec 31, 2022

Study Type : Plant Study

Additional Links

Substances : Cocoa

Diseases : Glyphosate Toxicity

Problem Substances : Glyphosate

[+]

Phytochemicals extracted from aerobically fermented cocoa pod husks have antibacterial and antifungal effects. Dec 31, 2013

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Genet Mol Res. 2014 ;13(3):7725-35. Epub 2014 Sep 26. PMID: 25299086

Article Published Date : Dec 31, 2013

Study Type : In Vitro Study

Additional Links

Substances : Cocoa, Fermented Foods and Beverages

Diseases : Bacillus subtilis infections, Fungal Infection, Klebsiella Infections, Pseudomonas aeruginosa, Salmonella Infections, Staphylococcus aureus infection, Staphylococcus epidermidis

Pharmacological Actions : Anti-Bacterial Agents, Antifungal Agents

Additional Keywords : Plant Extracts

[+]

Plant-derived phenolic compounds may have a protective effect on skin exposed to high levels of air pollution.Sep 05, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Antioxidants (Basel). 2019 Sep 6 ;8(9). Epub 2019 Sep 6. PMID: 31500121

Article Publish Status : This is a free article. Click here to read the complete article.

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mediators Inflamm. 2019 ;2019:1515621. Epub 2019 Jan 20. PMID: 30804705

Article Published Date : Dec 31, 2018

Study Type : In Vitro Study

Additional Links

Substances : Cocoa

Diseases : Inflammation, Obesity

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Anti-Obesity Agents

[+]

Theobromine though nonfluoridated toothpaste showed greater zones of inhibition than other commercially available fluoridated kid's toothpastes.Feb 28, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Dent Res J (Isfahan). 2019 Mar-Apr;16(2):76-80. PMID: 30820200

Article Published Date : Feb 28, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Nutr. 2017 ;4:36. Epub 2017 Aug 2. PMID: 28824916

Article Published Date : Dec 31, 2016

Study Type : Review

Additional Links

Substances : Cocoa, Polyphenols

Diseases : Cardiovascular Diseases

Pharmacological Actions : Antihypertensive Agents, Cardioprotective

[+]

This set of studies suggest a positive effect of cocoa polyphenols on memory and executive function.Jan 12, 2020

Click here to read the entire abstract

Pubmed Data : Plant Foods Hum Nutr. 2020 Jan 13. Epub 2020 Jan 13. PMID: 31933112

Article Published Date : Jan 12, 2020

Study Type : Review

Additional Links

Substances : Cocoa

Diseases : Cognitive Decline/Dysfunction

Pharmacological Actions : Neuroprotective Agents

[+]

Various natural substances may prove useful in the treatment of glaucoma.May 01, 2007

Click here to read the entire abstract

Pubmed Data : Expert Opin Emerg Drugs. 2007 May;12(2):195-8. PMID: 17604496

Article Published Date : May 01, 2007

Study Type : Commentary

Additional Links

Substances : Cocoa, Magnesium, Omega-3 Fatty Acids, Polyphenols

Diseases : Glaucoma

[+]

Cocao proanthocyanidins inhibit diabetes-induced cataract formation. Oct 01, 2010

Click here to read the entire abstract

Pubmed Data : J Pharmacol Exp Ther. 2010 Oct;335(1):149-54. Epub 2010 Jul 7. PMID: 14709774

Article Published Date : Oct 01, 2010

Additional Links

Substances : Cocoa

Diseases : Cataract, Diabetes: Cataract

Cocoa jQuery(function ($) { $(".node-field-image").click(function () { $(".node-field-image").toggleClass("open"); }); $(".node.topic>.colfull").click(function () { $(".node.topic>.colfull").toggleClass("open"); }); })

Focus Your Research

Click any topic below to filter + focus research

Cocoa is a Sub of the following Topic

View the Evidence: 215 Abstracts with Cocoa Research

Limited to Members Only

Currently Available Sorting Options

Dark chocolate cocoa may improve systemic oxidative status and inflammation in adults.Aug 31, 2024

Chocolate consumption could lower the risk of coronary heart disease, stroke, and diabetes.Jul 01, 2017

Chocolate consumption during pregnancy may reduce the likelihood of preeclampsia.May 01, 2008

Chocolate consumption in moderation may be associated with a decreased risk of heart failure.Apr 19, 2017

Chocolate consumption is associated with a substantial reduction in the risk of cardiometabolic disorders. Jan 01, 2011

Chocolate consumption is associated with lower risk of myocardial infarction and ischaemic heart disease.Jun 30, 2016

Chocolate consumption may be associated with reduced risk of cardiovascular disease.Jul 29, 2018

Chocolate could be a useful aid for recovery from exercise.Jun 18, 2018

Cocoa and dark chocolate supplementation reduced body weight, body mass index and waist circumference.Mar 18, 2018

Effects of cocoa consumption on cardiometabolic risk markers.Jun 17, 2024

Flavonoids have a promising role in improving visual function in patients with glaucoma and ocular hypertension.Sep 03, 2015

Meta-analysis: Chocolate, cocoa and flavan-3-ols improve insulin resistance, reduces serum insulin levels, and parameters associated with cardiovascular disease risk. Feb 01, 2012

The consumption of cocoa/dark chocolate reduced the serum fasting blood glucose and LDL cholesterol concentrations.Jun 04, 2021

The pooled results showed a 19% relative risk reduction of heart failure incidence with higher chocolate consumption.Jan 27, 2016

The results indicated the beneficial long-term effects of cocoa products intake on cardiometabolic biomarkers for T2D.Mar 05, 2022

The results of the meta-analysis showed a potential protective effect of moderate consumption of chocolate on cardiovascular risk.Jan 31, 2018

These findings support the concept that cocoa consumption plays an important role in the human metabolic pathway through reducing the oxidative stress.Dec 31, 2019

This review provides support for the use of polyphenol-rich interventions for improving cardiovascular risk markers in haemodialysis patients.Dec 10, 2017

A proprietary blend of standardized Punica granatum fruit rind and Theobroma cocoa seed extracts mitigates aging males' symptoms.Dec 31, 2021

A proprietary herbal blend containing extracts of Punica granatum fruit rind and Theobroma cocoa seeds increases serum testosterone level in healthy young males.Dec 31, 2022

Acute chocolate intervention can significantly affect human metabolism.Jul 06, 2017

Acute consumption of flavanol-rich cocoa beverage improves attenuated cutaneous microvascular function in healthy young African Americans.Oct 21, 2019

Acute dark chocolate ingestion is beneficial for hemodynamics.Mar 06, 2017

Adolescents who consume 2 servings a week or more of chocolate have longer leukocyte telomere length compared with non-consumers.May 31, 2019

Antioxidant protection from bioactive compounds present in fruit and vegetables could have an adjuvant role in fibromyalgia treatment.Nov 20, 2016

Association between chocolate consumption and fatness in European adolescents.Oct 16, 2013

Cacao bean husk ethanol extract as mouth rinse for children has been proven highly effective in reducing mutans streptococci colony counts.Mar 31, 2016

Cacao flavanols may be a useful food material that can improve variable mood conditions in middle-aged women.Sep 02, 2023

Chocolate consumption confers reduced risks of mortality from all causes, cardiovascular disease, and Alzheimer's disease.Jul 28, 2021

Chocolate consumption is inversely associated with calcified atherosclerotic plaque in the coronary arteries.Dec 01, 2010

Chocolate consumption is inversely associated with prevalent coronary heart disease.Sep 19, 2010

Chocolate consumption may improve liver enzymes and protect against insulin resistance.Mar 16, 2016

Chocolate consumption may reduce the risk of heart attack and stroke not using antihypertensive medication.Jul 01, 2010

Chocolate consumption was associated with a significant lower risk of gestational diabetes in Japanese women.Jul 23, 2019

Chocolate consumption was associated with a significant lower risk of stroke in women.Mar 03, 2017

Chocolate enriched by extra virgin olive oil improves endothelial function and oxidative stress in patients with diabetes.Apr 06, 2021

Chocolate intake during pregnancy may reduce the risks of preeclampsia and gestational hypertensionAug 01, 2010

Chocolate intake is associated with better cognitive function.Apr 30, 2016

Chocolate intake was associated with a lower risk of cognitive decline.May 05, 2016

Chocolate intake was inversely associated with type 2 diabetes.Dec 31, 2016

Chocolate milk is a relatively unexplored recovery aid and warrants further attention.Nov 30, 2015

Chronic cocoa consumption improves endothelial function in postmenopausal women with high cholesterol.Sep 01, 2009

Chronic supplementation with dark chocolate as a rich source of polyphenols positively modulates exercise-induced intestinal damage in elite football athletes.Sep 27, 2023

Cocoa and unripe banana flour beverages improve anthropometric and biochemical markers in overweight women.May 31, 2021

Cocoa extract supplementation reduced cardiovascular disease death by 27%.Mar 15, 2022

Cocoa flavanol consumption improves lower extremity endothelial function.Oct 16, 2022

Cocoa flavanol intake has the potential to reduce the 10-year risk of CV morbidity and mortality even in this healthy cohort by 20–30 % and 30–40 % respectively.Sep 08, 2015

Cocoa flavanols in peripheral artery disease.Jan 31, 2024

Cocoa flavanols intake benefits cognitive function in type 1 diabetes.Jun 24, 2019

Cocoa flavanols reverse vascular dysfunction in diabetics.Jun 01, 2009

Cocoa ingestion protects plasma lipids in healthy males against ex vivo oxidative conditions.Jul 31, 2018

Cocoa polyphenols improve endothelial function via Nox2 down-regulation in NASH patients.Nov 12, 2017

Cocoa powder has a positive effect on inflammatory mediators in patients at high risk of cardiovascular disease. Nov 01, 2009

Cocoa-derived flavanols are effective prebiotics as demonstrated in healthy human volunteers.Nov 10, 2010

Cocoa-rich chocolate and body composition in postmenopausal women.Jan 13, 2021

Consumption of almonds alone or combined with dark chocolate and cocoa may improve lipid/lipoprotein profiles.Nov 28, 2017

Consumption of chocolate containing high concentrations of cocoa enhanced vascular endothelial function.Aug 08, 2017

Consumption of dark chocolate may be associated with reduced odds of clinically relevant depressive symptoms.Jul 28, 2019

Consumption of high flavanol dark chocolate confers modest improvements in cardiovascular function.Jul 31, 2015

Consumption of polyphenols results in a significant improvement in an established marker of cardiovascular risk in hypertensive participants.May 09, 2016

Cutaneous photoprotective activity of a short-term ingestion of high flavanol cocoa.Jan 19, 2019

Daily consumption of 40 g of dark chocolate during a period of 2 weeks reduces the urinary excretion of the stress hormone cortisol and catecholamines, while reducing other metabolic indicators of stress.Dec 01, 2009

Dark chocolate (70% cocoa) attenuates the inflammatory marker TNF-α in patients on hemodialysis.Jan 31, 2023

Dark chocolate attenuates intracellular pro-inflammatory reactivity to acute psychosocial stress in men.Apr 27, 2016

Dark chocolate attenuates subsequent food intake in postmenopausal women.Aug 31, 2017

Dark chocolate consumption increases HDL cholesterol concentration and chocolate fatty acids may inhibit lipid peroxidation in healthy humans.Dec 01, 2008

Dark chocolate has beneficial effects on exercise capacity in sedentary subjects.Aug 04, 2016

Dark chocolate has beneficial effects on serum adiponectin, biochemical and inflammatory parameters in diabetic patients.Dec 31, 2017

Dark chocolate intake and cardiovascular diseases.Jan 09, 2024

Dark chocolate intake may reduce fatigue and mediate cognitive function and gray matter volume.Dec 31, 2021

Dark chocolate intake positively modulates redox status and markers of muscular damage in elite football athletes.Dec 31, 2017

Dark chocolate reduced the oxygen cost of moderate intensity exercise.Dec 31, 2014

Cocoa

View the Evidence:
215 Abstracts with Cocoa Research