Cannabinoids

Name	AC	CK
Epilepsy	60	305
Multiple Sclerosis	44	203
Anxiety	27	135
Inflammation	63	115
Neuropathic Pain	23	94
Parkinson's Disease	28	76
Chronic Pain	16	71
Seizures	12	66
Dravet syndrome	8	64
Cancers: All	44	63
Inflammatory Bowel Diseases	15	58
Autism Spectrum Disorders	10	57
Epilepsy: Childhood	6	53
Sleep Disorders	6	47
Stroke	5	45
Alzheimer's Disease	32	42
Neurodegenerative Diseases	29	42
Stroke: Attenuation/Recovery	6	39
Brain Inflammation	26	38
Breast Cancer	27	36
Hypertension	6	36
Lennox-Gastaut Syndrome	8	36
Tourette Syndrome	5	36
Pain	6	35
Schizophrenia	16	32
Depression	17	31
Glioblastoma Multiforme	10	31
Oxidative Stress	21	31
Glioma	18	30
Anxiety Disorders	8	29
Diabetes Mellitus: Type 2	6	28
Huntington Disease	11	28
Lipopolysaccharide-Induced Toxicity	20	28
Morphine Tolerance/Dependence	5	28
Obesity	8	27
Insomnia	4	25
Post-Traumatic Stress Disorders (PTSD)	11	25
Psychoses	7	25
Amyotrophic lateral sclerosis (ALS)	4	24
Arthritis	5	24
Acne	4	22
Lung Cancer	16	22
Memory Disorders	7	22
Muscle Spasticity	3	22
Coronavirus Infection	20	21
Hyperalgesia	9	21
Marijuana Addiction/Withdrawal	3	21
Hypoglycemia	1	20
Opioid Tolerance/Dependence	1	20
Psychiatric Disorders	9	20
Sturge-Weber Syndrome	2	20
Glioblastoma	13	19
Spinal Cord Injuries	6	19
Stroke: Ischemic	4	19
Colitis	9	18
Nonalcoholic fatty liver disease (NAFLD)	4	18
Brain Ischemia	8	17
Cancer: Pain	5	15
Dry Skin	1	15
Ulcerative Colitis	2	15
Brain Cancer	3	14
Cerebral Ischemia	7	14
Chemotherapy-Induced Toxicity: Cisplatin	7	14
Colon Cancer	10	14
HIV Infections	4	14
Ovarian Cancer	4	14
Brain Damage: Hypoxic Ischemic Insult	6	13
Brain: Microglial Activation	6	13
Breast Cancer: Triple Negative	8	13
Encephalopathy	2	13
Obsessive-Compulsive Disorder	3	13
Prostate Cancer	11	13
Amyotrophic Lateral Sclerosis	8	12
Bladder Dysfunction	2	12
Cancer Metastasis	9	12
Colorectal Cancer	10	12
Epileptic Seizures	2	12
Muscle Damage: Exercise-Induced	2	12
Pancreatic Cancer	9	12
Periodontitis	2	12
Endocannabinoid Disorders	2	11
Astrocytoma	4	10
Attention Deficit Hyperactivity Disorder	1	10
Brachial Plexus Neuropathies	1	10
Child Behavior Disorders	1	10
Cocaine Addiction	1	10
Delirium: Drug-Induced	1	10
Diabetic Complications	6	10
Fibromyalgia	1	10
Gastroparesis	1	10
Impairment: Driving Related	1	10
Learning disorders	1	10
Low Back Pain	1	10
Migraines	1	10
Organ Transplantation: Kidney	1	10
Overactive Bladder	1	10
Pancreatitis: Chronic	1	10
Peripheral Nerve Diseases	1	10
Quality of Life: Poor	1	10
Rett Syndrome	1	10
Social Anxiety Disorder (SAD)	1	10
Temporal Lobe Epilepsy (TLE)	1	10
Temporomandibular Joint Disorders	1	10
Tuberous Sclerosis	1	10
Ulcer: Aphthous	1	10
Vaccine-induced Toxicity	1	10
Allodynia	5	9
Cardiovascular Diseases	4	9
Lymphoma	4	9
Melanoma	6	9
Dementia	5	8
Diabetes Mellitus: Type 1	4	8
Gastrointestinal Inflammation	4	8
Skin Cancer	5	8
Traumatic Memory Formation	4	8
Alcoholic Liver Disease	2	7
Autoimmune Diseases	5	7
Chemotherapy-Induced Toxicity: Paclitaxel	4	7
Endocannabinoid System	7	7
Glaucoma	4	7
Metabolic Diseases	2	7
Middle Cerebral Artery Occlusion (MCAO)	4	7
Myocardial Infarction	4	7
Oral Mucositis	4	7
Psychiatric Disorder: Conditioned Fear	4	7
Sepsis	4	7
Bladder Cancer	5	6
Chemotherapy-Induced Toxicity: Peripheral Neuropathy	3	6
Hypertension: Pulmonary	3	6
Liver Cancer	5	6
Osteoarthritis	5	6
Psoriasis	5	6
Traumatic Brain Injury	3	6
Asthma	3	5
Brain: Oxidative Stress	3	5
Cachexia	4	5
Chemotherapy-Induced Toxicity: Doxorubicin	3	5
Diabetes Mellitus: Type 1: Prevention	3	5
Drug Abuse	3	5
High Fat Diet	3	5
Liver Fibrosis	3	5
Multiple Myeloma	3	5
Acute Myeloid Leukemia	2	4
Alcohol Toxicity	3	4
Alcohol Withdrawal	2	4
Bone Fractures	2	4
Brain Damage	3	4
Brain Injury: Traumatic	2	4
Cocaine Toxicity	2	4
Colon Cancer: Prevention	2	4
Dermatitis	2	4
Diabetes: Cataract	2	4
Diabetic Neuropathies	1	4
Emesis	1	4
Endotoxemia	2	4
Eye Damage	1	4
Febrile Seizures	2	4
Heart Failure	2	4
Iron Overload	2	4
Ischemia	2	4
Liver Damage	2	4
Metabolic Syndrome X	1	4
Myocardial Ischemia	2	4
Psychotic Disorders	3	4
Vomiting	1	4
Wound Healing	4	4
Aging	2	3
Astrocytoma: Grade IV	1	3
Autism	2	3
Cachexia: Cancer	3	3
Cancers: Drug Resistant	3	3
Chemotherapy and Radiation Toxicity	2	3
Chemotherapy-Induced Nausea	3	3
Coronavirus Disease (Covid-19)	3	3
Drug Addiction	2	3
Encephalomyelitis	2	3
Epidermolysis Bullosa	1	3
Epilepsy: Infant	1	3
Epilepsy: Malignant Migrating Partial Seizures	1	3
Fibrosis	2	3
Gastric Cancer	3	3
Gastrointestinal Diseases	2	3
Gliomas	2	3
Hydrogen Peroxide Induced Toxicity	3	3
Hyperglycemia	2	3
Irritable Bowel Syndrome	2	3
Lichenoid Dermatitis	1	3
Neuroblastoma	2	3
Squamous cell carcinoma	1	3
Thyroid Cancer	2	3
Aging: Brain	1	2
Air Pollution Linked Toxicity	1	2
Alcohol Addiction	2	2
Aluminum Toxicity	1	2
Amphetamine Addiction/Withdrawal	1	2
Angelman Syndrome	1	2
Appetite Disorders: Loss/Lack of	1	2
Arteriosclerosis	1	2
Atopic Dermatitis	1	2
Bipolar Disorder	1	2
Brain Edema	1	2
Breast Cancer: Lung Metastasis	1	2
Breast Cancer: Metastatic	1	2
Breast Cancer: Prevention	1	2
Cachexia: Chemotherapy Induced	1	2
Cancers: Canine	1	2
Carcinoma: Non-Small-Cell Lung	2	2
Cardiac Arrhythmias	1	2
Cardiomyopathy	1	2
Cerebral Hypoperfusion	1	2
Chemically-Induced Liver Damage	1	2
Chemotherapy-Induced Toxicity: 5-fluorouracil	1	2
Chemotherapy-Induced Toxicity: Oxaliplatin	1	2
Chemotherapy-Induced Toxicity: Vincristine	1	2
Cholangiocarcinoma	1	2
Cocaine Withdrawal	1	2
Cognitive Decline/Dysfunction	1	2
Degenerative Disk Disease	1	2
Depression	1	2
Depressive Disorder	1	2
Dermatitis: Contact	1	2
Diabetes: Cardiovascular Illness	1	2
Diabetes: Memory Problems	1	2
Diabetic Neuropathy	1	2
Diabetic Retinopathy	1	2
Diarrhea	1	2
Dysbiosis	1	2
Endometrial Cancer	1	2
Endothelial Dysfunction	1	2
Epilepsy: Drug-Induced	1	2
Estrogen Deficiency	1	2
Fatty Liver	1	2
Friedreich Ataxia	1	2
Fulminant Hepatic Failure	1	2
Gastroschisis	1	2
Head and Neck Cancer	1	2
Headache	2	2
Heart Attack	1	2
Hepatic Encephalopathy	1	2
Hepatitis C	2	2
Hypersensitivity	1	2
Hypersensitivity: Type IV	1	2
Hypothyroidism	1	2
Hypoxia	1	2
Infant Neurological Development	1	2
Inflammation: Neutrophil-Mediated	1	2
Influenza	2	2
Insulin Resistance	1	2
Interstitial Lung Diseases	1	2
Leukemia	2	2
Lipid Peroxidation	1	2
Liver Cirrhosis	1	2
Liver Failure: Acute	1	2
Liver Injury: Ischemia/reperfusion	1	2
Malaria	1	2
Memory Disorders: Drug-Induced	1	2
Mesothelioma	1	2
Mitochondrial Dysfunction	1	2
Muscle Soreness	1	2
Myocardial Fibrosis	1	2
Myocarditis: Autoimmune	1	2
Neonatal Stroke	1	2
Neuralgia	1	2
Neurologic Disorders	2	2
Osteoporosis	2	2
Osteosarcoma	2	2
Postmenopausal Disorders	1	2
Prion Diseases	1	2
Rhabdomyosarcoma	1	2
Sciatic Nerve Crush Injury	1	2
Skin Diseases: Inflammatory	1	2
Spinal Cord Inflammation	1	2
Staphylococcus aureus: Methicillin-resistant (MRSA)	2	2
Tardive Dyskinesia	1	2
Tremor	1	2
Ultraviolet Radiation Induced Damage	2	2
Urinary Bladder Diseases	1	2
Uveitis	1	2
Vitamin D Deficiency	1	2
AIDS	1	1
Acetaminophen (Tylenol) Toxicity	1	1
Acquired Immunodeficiency Syndrome	1	1
Acute T cell Leukemias	1	1
Acute lymphoblastic leukemia (ALL)	1	1
Aging Skin	1	1
Allergic Airway Diseases	1	1
Allergies	1	1
Anorexia	1	1
Appetite Disorders	1	1
Arrhythmias: Cardiac	1	1
Atherosclerosis	1	1
Bone Diseases	1	1
Burkitt Lymphoma	1	1
Cadmium Poisoning	1	1
Cancers	1	1
Cancers: Multi-Drug Resistant	1	1
Candida Albicans	1	1
Candida Infection	1	1
Cat Diseases	1	1
Central Nervous System Diseases	1	1
Cervical Cancer	1	1
Chronic Pelvic Pain Syndrome	1	1
Cirrhosis	1	1
Clostridium Infections	1	1
Cough	1	1
Diabetes: Cognitive Dysfunction	1	1
Dog Diseases	1	1
Drug Toxicity: Methotrexate	1	1
Dry Eye Syndromes	1	1
Ebola Virus Infections	1	1
Eczema	1	1
Escherichia coli Infections	1	1
Eye Diseases	1	1
Gram-Positive Bacterial Infections	1	1
Herpes Simplex Virus Type 2	1	1
Herpes: Kaposi-Associated	1	1
High Sugar Diet	1	1
Immune Disorders	1	1
Immune Dysregulation: TH1/TH2 imbalance	1	1
Kaposi Disease	1	1
Kidney Cancer	1	1
Kidney Damage	1	1
Leishmaniasis	1	1
Leukemia: T-cell acute Lymphoblastic	1	1
Lung Injury: Acute	1	1
Methicillin-resistant Staphylococcus aureus	1	1
Mood Disorders	1	1
Mycobacterium Tuberculosis	1	1
Nausea: Chemotherapy-Induced	1	1
Neurological Conditions	1	1
Oral Cancer	1	1
Peripheral Neuropathies	1	1
Pesticide Toxicity	1	1
Prostate: PSA Doubling	1	1
Prostatitis: Chronic	1	1
Pruritus	1	1
Pseudomonas aeruginosa	1	1
Radiation	1	1
Rheumatoid Arthritis	1	1
Salmonella Infections	1	1
Skin Diseases	1	1
Staphylococcus aureus infection	1	1
Subarachnoid hemorrhage	1	1
Testicular Cancer	1	1
Tobacco Addiction/Withdrawal	1	1
Zika Virus	1	1

Name	AC	CK
Neuroprotective Agents	176	405
Anti-Inflammatory Agents	178	398
Anticonvulsants	69	395
Analgesics	64	276
Anti-Anxiety Agents	35	159
Apoptotic	102	146
Antiproliferative	91	145
Antioxidants	52	73
Immunomodulatory	31	61
Tumor Necrosis Factor (TNF) Alpha Inhibitor	35	59
Antidepressive Agents	20	47
Chemotherapeutic	24	43
Vasodilator Agents	6	41
Anti-metastatic	30	40
Interleukin-6 Downregulation	20	40
Angiogenesis Inhibitors	19	35
Antihypertensive Agents	6	35
Antineoplastic Agents	26	35
Antinoceceptive	12	33
NF-kappaB Inhibitor	17	26
Chemopreventive	10	25
Hypoglycemic Agents	4	25
Cyclooxygenase 2 Inhibitors	10	24
Hepatoprotective	12	24
Interleukin-1 beta downregulation	17	24
Anti-Apoptotic	14	22
Cardioprotective	12	20
Chemoprotective Agents	10	20
Gastrointestinal Agents	9	20
Antiviral Agents	17	17
Immunosuppressive Agents	6	17
Autophagy Up-regulation	10	16
Chemosensitizer	12	15
Cell cycle arrest	10	13
Antipsychotic Agents	8	12
Antispasmodic	2	12
Gastroprotective	3	12
Matrix metalloproteinase-9 (MMP-9) inhibitor	2	12
Vascular Endothelial Growth Factor Inhibitors	3	12
Anticarcinogenic Agents	8	11
Anxiolytic	2	11
Brain-derived neurotrophic factor modulator	6	11
Anti-Tumor	5	10
GABA Modulators	1	10
Anti-Fibrotic	6	9
Hypolipidemic	3	9
Interferon Gamma Reducer	5	9
Neurogenesis	7	9
Nitric Oxide Inhibitor	5	8
Anti-Bacterial Agents	7	7
Interleukin-8 downregulation	5	7
Superoxide Dismutase Up-regulation	3	7
P38 Mitogen-Activated Protein Kinase Modulator	2	6
Vascular Cell Adhesion Molecule-1 Inhibitor	2	6
Anti-Angiogenic	5	5
Appetite Stimulants	3	5
Cannabinoid Receptor Antagonist/Inverse Agonist	3	5
Interleukin-4 downregulation	3	5
Neuritogenic	3	5
Caspase-3 Activation	3	4
Enzyme Inhibitors	2	4
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	4	4
Interleukin-10 downregulation	2	4
Interleukin-10 upregulation	2	4
Interleukin-17 downregulation	3	4
Matrix metalloproteinase-2 (MMP-2) inhibitor	2	4
Osteoprotective	3	4
Pancreato Protective Agents	2	4
Prostaglandin PGE2 downregulation	2	4
Vascular Endothelial Growth Factor A Inhibitor	2	4
Vascular Endothelial Growth Factor Regulator	2	4
Bcl-2 protein down-regulation	2	3
Cyclooxygenase 1 Inhibitor	3	3
Cytotoxic	2	3
Immunomodulatory: Th17 downregulation	2	3
Interleukin-12 downregulation	2	3
Interleukin-2 Downregulation	2	3
Nrf2 activation	3	3
Prophylactic Agents	2	3
Radiosensitizer	2	3
Renoprotective	2	3
Tumor Suppressor Protein p53 Upregulation	3	3
Aldose reductase inhibitor	1	2
Anti-Androgen	1	2
Anti-Cachexic Agents	2	2
Anti-atherogenic	1	2
Anticholesteremic Agents	1	2
Calcium Channel Blockers	1	2
Cyclooxygenase Inhibitors	1	2
Enzyme Activators	1	2
Epidermal growth factor receptor (EGFR) inhibitor	1	2
Glycine Agents	1	2
Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor	1	2
Hypnotics and Sedatives	1	2
Immunomodulatory: T-Cell down-regulation	1	2
Immunostimulatory	1	2
Interleukin-5 downregulation	1	2
Intracellular adhesion molecule-1 (ICAM-1)	1	2
Malondialdehyde Down-regulation	1	2
Matrix metalloproteinase-1 (MMP-1) inhibitor	2	2
MicroRNA modulator	2	2
Neuroplasticity enhancement	1	2
Photoprotective	2	2
Redox Modulator	1	2
Sedative effects	1	2
Topoisomerase II Inhibitor	2	2
Transforming growth factor beta (TGF-β) inhibitor	1	2
Vanilloid Receptor-1 Modulator	1	2
Vasoprotective	1	2
Wnt/β-catenin signaling pathway modulation	2	2
interleukin-13 down-regulation	1	2
Alpha-glucosidase inhibitor	1	1
Anti-Allergic Agents	1	1
Anti-Infective Agents	1	1
Anti-Proliferative	1	1
Anti-Psychotic	1	1
Antifungal Agents	1	1
Antimicrobial	1	1
Caspase-8 activation	1	1
Caspase-9 Activation	1	1
Heat Shock Protein Down-Regulation	1	1
Interleukin-1 alpha downregulation	1	1
Interleukin-18 upregulation	1	1
Interleukin-2 upregulation	1	1
NADPH Oxidase Inhibitors	1	1
Neuroimmunomodulation	1	1
Paraptosis	1	1
Radioprotective	1	1
Regenerative	1	1
Transient receptor potential vanilloid type-2 activation	1	1
apoptosis	1	1

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Clin Sleep Med. 2024 May 1 ;20(5):753-763. PMID: 38174873

Article Published Date : Apr 30, 2024

Study Type : Human Study

Additional Links

Substances : Cannabidiol

Diseases : Insomnia

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Cannabidiol for rapid eye movement sleep behavior disorder. Mar 21, 2021

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Pubmed Data : Mov Disord. 2021 Mar 22. Epub 2021 Mar 22. PMID: 33754375

Article Published Date : Mar 21, 2021

Study Type : Human Study

Additional Links

Substances : Cannabidiol

Diseases : Parkinson's Disease

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Cannabidiol improves maternal obesity-induced behavioral, neuroinflammatory and neurochemical dysfunctions in the juvenile offspring.Apr 09, 2024

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Pubmed Data : Brain Behav Immun. 2024 Apr 10 ;119:301-316. Epub 2024 Apr 10. PMID: 38608740

Cannabidiol reduced the frequency of both focal and generalised seizures with 50 % seizure reduction in 76 % of the cohort.Jun 20, 2024

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Pubmed Data : Epilepsy Behav. 2024 Jun 21 ;157:109904. Epub 2024 Jun 21. PMID: 38908033

Article Published Date : Jun 20, 2024

Study Type : Human Study

Additional Links

Substances : Cannabidiol

Diseases : Lennox-Gastaut Syndrome

Pharmacological Actions : Anticonvulsants

[+]

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Pubmed Data : Isr Med Assoc J. 2017 Feb ;19(2):79-84. PMID: 28457055

Article Published Date : Jan 31, 2017

Study Type : Human Study

Additional Links

Substances : Cannabidiol, Hemp Seed

Diseases : Vaccine-induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Antinoceceptive , Neuroprotective Agents

Additional Keywords : Plant Extracts

Anti Therapeutic Actions : Vaccination: HPV (Gardasil)

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CBD formulations in patients with temporomandibular disorders have proven to be a successful treatment for reducing pain, muscle tension, and bruxing activity.Feb 28, 2024

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Pubmed Data : Biomed Pharmacother. 2023 Aug ;164:115016. Epub 2023 Jun 13. PMID: 37321059

Article Published Date : Jul 31, 2023

Study Type : Human Study

Additional Links

Substances : Cannabidiol

Diseases : Hypertension

Pharmacological Actions : Antihypertensive Agents

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Efficacy and tolerance of cannabidiol in the treatment of epilepsy in patients with Rett syndrome.Jul 23, 2023

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Pubmed Data : Epilepsia Open. 2023 Jul 24. Epub 2023 Jul 24. PMID: 37485779

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Pubmed Data : Epilepsy Behav. 2015 Apr 29. Epub 2015 Apr 29. PMID: 25935511

Article Published Date : Apr 28, 2015

Study Type : Human Study

Additional Links

Substances : Cannabidiol, Cannabis

Diseases : Epilepsy, Epilepsy: Childhood

Pharmacological Actions : Anticonvulsants

Additional Keywords : Plant Extracts

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Evaluating cannabidiol expectancy effects on acute stress and anxiety in healthy adults.Apr 03, 2021

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Pubmed Data : Psychopharmacology (Berl). 2021 Apr 4. Epub 2021 Apr 4. PMID: 33813611

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Pubmed Data : Clin Gastroenterol Hepatol. 2013 Oct ;11(10):1276-1280.e1. Epub 2013 May 4. PMID: 23648372

Article Published Date : Sep 30, 2013

Study Type : Human Study

Additional Links

Substances : Cannabinoids , Cannabis, Delta-tetrahydrocannabinol (THC)

Diseases : Inflammatory Bowel Diseases

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Natural Substances Versus Drugs, Significant Treatment Outcome

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Long-term add-on CBD treatment had an acceptable safety profile in patients with Lennox-Gastaut syndrome and led to sustained reductions in seizures.Feb 10, 2019

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Pubmed Data : PLoS One. 2017 ;12(4):e0176416. Epub 2017 Apr 25. PMID: 28441459

Article Published Date : Dec 31, 2016

Study Type : Human Study

Additional Links

Substances : Cannabinoids , Cannabis

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Additional Keywords : Risk Reduction, Significant Treatment Outcome

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Orally administered cannabis extract may provide a therapeutic option to other drugs in the treatment of spasticity in patients with multiple sclerosisAug 01, 2004

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Pubmed Data : Mult Scler. 2004 Aug;10(4):417-24. PMID: 15327040

Article Published Date : Aug 01, 2004

Study Type : Human Study

Additional Links

Substances : Cannabidiol

Diseases : Multiple Sclerosis, Muscle Spasticity

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Palmitoylethanolamide and cannabidiol prevent inflammation-induced hyperpermeability of the human gut.Jan 03, 2019

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The results reported here are very promising and indicate that CBD-enriched cannabis extract may ameliorate multiple autism spectrum disorders symptoms.Dec 31, 2018

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These results suggest that CBD has anxiolytic properties.Jan 31, 2004

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Pubmed Data : J Clin Pharmacol. 2015 Nov 26. Epub 2015 Nov 26. PMID: 26608223

Article Published Date : Nov 25, 2015

Study Type : Human Study

Additional Links

Substances : Cannabidiol, Delta-tetrahydrocannabinol (THC)

Diseases : Bladder Dysfunction , Multiple Sclerosis

Additional Keywords : Plant Extracts

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White matter integrity after cannabidiol administration for treatment resistant epilepsy.Mar 07, 2021

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Pubmed Data : Epilepsy Res. 2021 Mar 8 ;172:106603. Epub 2021 Mar 8. PMID: 33725662

Article Published Date : Mar 07, 2021

Study Type : Human Study

Additional Links

Substances : Cannabidiol

Diseases : Epilepsy

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Anandamide is a potent and selective inhibitor of the proliferation of breast cancer cells.Jul 06, 1998

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Pubmed Data : Proc Natl Acad Sci U S A. 1998 Jul 7 ;95(14):8375-80. PMID: 9653194

Article Published Date : Jul 06, 1998

Study Type : Human In Vitro

Additional Links

Substances : Anandamide, Cannabinoids

Diseases : Breast Cancer

Pharmacological Actions : Antiproliferative

Additional Keywords : Cannabinoid Receptors, Dose Response

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Cannabidiol causes vasorelaxation of the human mesenteric artery.Aug 31, 2015

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Pubmed Data : Cardiovasc Res. 2015 Sep 1 ;107(4):568-78. Epub 2015 Jun 19. PMID: 26092099

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Pubmed Data : J Pharm Pharmacol. 2004 Mar ;56(3):291-7. PMID: 15025853

Article Published Date : Feb 29, 2004

Study Type : Human In Vitro

Additional Links

Substances : Cannabidiol, Cannabinoids

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Phytocannabinoids could be efficient and safe novel treatments in the management of cutaneous inflammations.Apr 19, 2016

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Pubmed Data : Exp Dermatol. 2016 Apr 20. Epub 2016 Apr 20. PMID: 27094344

Article Published Date : Apr 19, 2016

Study Type : Human In Vitro

Additional Links

Substances : Cannabidiol, Cannabidivarin, Cannabigerol , Cannabigerovarin , Cannabinoids

Diseases : Acne, Dry Skin

Pharmacological Actions : Anti-Inflammatory Agents

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The present data suggest that targeting CB(1)/CB(2) may have therapeutic potential for the treatment of mantle cell lymphoma.Oct 31, 2006

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Pubmed Data : Mol Pharmacol. 2006 Nov ;70(5):1612-20. Epub 2006 Aug 25. PMID: 16936228

Article Published Date : Oct 31, 2006

Study Type : Human In Vitro

Additional Links

Substances : Cannabinoids , Cannabinoids: Synthetic

Diseases : Lymphoma

Pharmacological Actions : Apoptotic, P38 Mitogen-Activated Protein Kinase Modulator

Additional Keywords : Selective Cytotoxicity

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The proapoptotic effect of cannabinoids on tumor cells is mediated by a ceramide dependent upregulation of the stress protein p8.Mar 31, 2006

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Pubmed Data : Biofactors. 2024 May 17. Epub 2024 May 17. PMID: 38760945

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Pubmed Data : Perm J. 2016 Oct 12 ;20(4). Epub 2016 Aug 12. PMID: 27768570

Article Published Date : Oct 11, 2016

Study Type : Human: Case Report

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Substances : Cannabidiol

Diseases : Anxiety Disorders, Insomnia, Post-Traumatic Stress Disorders (PTSD)

Pharmacological Actions : Anti-Anxiety Agents

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Cannabidiol's cytotoxicity in pancreatic cancer is induced via an upregulation of ceramide synthase 1 and ER stress.May 07, 2024

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Pubmed Data : Phytomedicine. 2020 Nov 30 ;81:153426. Epub 2020 Nov 30. PMID: 33341026

Article Published Date : Nov 29, 2020

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Cannabinoids , Cannabis

Diseases : Inflammation, Liver Fibrosis, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Hepatoprotective

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Activation of cannabinoid system may have protective actions on both liver and brain induced by cocaine, minimizing inflammatory injury promoted by cocaine.Dec 31, 2014

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Pubmed Data : Inflammopharmacology. 2018 Oct 5. Epub 2018 Oct 5. PMID: 30291491

Article Published Date : Oct 04, 2018

Study Type : Animal Study

Additional Links

Substances : Cannabidiol, Cannabis

Diseases : Multiple Sclerosis

Pharmacological Actions : Immunomodulatory

Additional Keywords : Natural Substances Versus Drugs

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Pubmed Data : Brain Behav Immun. 2024 May 15 ;119:945-964. Epub 2024 May 15. PMID: 38759736

Article Published Date : May 14, 2024

Study Type : Animal Study

Additional Links

Substances : Cannabidiol

Diseases : Brain Inflammation , Post-Traumatic Stress Disorders (PTSD)

Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents

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Cannabidiol controls the exaggerated inflammatory response observed in an animal model of asthma.Dec 31, 2014

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Pubmed Data : Behav Pharmacol. 2020 May 29. Epub 2020 May 29. PMID: 32483052

Cannabidiol enhanced the ability of THC to inhibit cell proliferation, induce cell cycle arrest and apoptosis.Dec 31, 2009

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Pubmed Data : Mol Cancer Ther. 2010 Jan ;9(1):180-9. Epub 2010 Jan 6. PMID: 20053780

Article Published Date : Dec 31, 2009

Study Type : Animal Study, In Vitro Study

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Substances : Cannabidiol, Delta-tetrahydrocannabinol (THC)

Diseases : Cancer Metastasis, Glioblastoma

Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, Cell cycle arrest

Additional Keywords : Cannabinoid Receptors, Natural Substance Synergy

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Cannabidiol enhanced the hippocampal immune response and autophagy of APP/PS1 Alzheimer's mice.Dec 31, 2020

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Pubmed Data : Life Sci. 2021 Jan 1 ;264:118624. Epub 2020 Oct 21. PMID: 33096116

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Substances : Cannabidiol

Diseases : Alzheimer's Disease

Pharmacological Actions : Immunostimulatory, Neuroprotective Agents

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Cannabidiol enhances cytotoxicity of anti-cancer drugs in human head and neck squamous cell carcinoma.Jan 25, 2020

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Pubmed Data : Eur J Pharmacol. 2005 Apr 11 ;512(2-3):199-205. PMID: 15840405

Article Published Date : Apr 10, 2005

Study Type : Animal Study

Additional Links

Substances : Cannabidiol

Pharmacological Actions : Antipsychotic Agents

Additional Keywords : Antipsychotic Agents, Cannabidiol, Natural Substances Versus Drugs

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Cannabidiol exhibits anxiolytic-like effects and antipsychotic-like effects.Mar 14, 2024

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Pubmed Data : Neurosci Lett. 2024 Mar 15 ;826:137723. Epub 2024 Mar 11. PMID: 38467272

Article Published Date : Mar 14, 2024

Study Type : Animal Study

Additional Links

Substances : Cannabidiol

Diseases : Anxiety, Schizophrenia

Pharmacological Actions : Anti-Anxiety Agents

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Cannabidiol improves haloperidol-induced motor dysfunction in zebrafish.Mar 03, 2023

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Pubmed Data : Acta Neuropsychiatr. 2024 May 21:1-30. Epub 2024 May 21. PMID: 38770713

Article Published Date : May 20, 2024

Study Type : Animal Study

Additional Links

Substances : Cannabidiol

Diseases : Brain Inflammation , Parkinson's Disease

Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents

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Cannabidiol improves the cognitive function of SAMP8 AD model mice involving the microbiota-gut-brain axis.Jun 01, 2024

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Pubmed Data : J Toxicol Environ Health A. 2024 Jun 2 ;87(11):471-479. Epub 2024 Apr 9. PMID: 38590254

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View the Evidence: 922 Abstracts with Cannabinoids Research

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Efficacy, safety, and regulation of cannabidiol on chronic pain.Jun 30, 2022

Therapeutic potential of cannabidiol (CBD) in anxiety disorders.Jun 20, 2024

A review and meta-analysis of the efficacy and safety of cannabidiol in epilepsy.Nov 02, 2018

A systematic review and meta-analysis off the effects of cannabinoids in Amyotrophic lateral sclerosis murine models.Dec 05, 2018

Adjunctive CBD resulted in a greater reduction in convulsive seizure frequency.Feb 09, 2020

Cannabinoids may have possible therapeutic properties for the management of the multiple sclerosis.Nov 19, 2010

Cannabinoids significantly reduced infarct volume and improve functional outcome in experimental stroke models.Feb 28, 2015

Selective cannabinoids provide a small analgesic benefit in patients with chronic neuropathic pain.May 18, 2017

The median effective dose of morphine administered in combination with THC is 3.6 times lower than of morphine alone.Mar 21, 2017

This meta-analysis and systematic review has highlighted the haemodynamic effects of CBD.Dec 31, 2016

Cannabidiol Treatment for Neurological, cognitive, and psychiatric symptoms in Sturge-Weber Syndrome.Jan 31, 2023

A case report of a female patient who demonstrated disease response after declining standard therapy and taking a combination of Laetrile and CBD oil.Jul 31, 2019

A randomized controlled trial of topical cannabidiol for the treatment of thumb basal joint arthritis.Jun 30, 2022

A single dose of cannabidiol reduces blood pressure in healthy volunteers.Jun 14, 2017

A tetrahydrocannabinol:cannabidiol (THC:CBD) extract is efficacious for relief of pain in patients with advanced cancer pain not fully relieved by strong opioids.Jul 01, 2009

Acute cannabidiol administration at a dose of 300 mg decreased anxiety in patients with Parkinson's disease.Jan 06, 2020

Add-on cannabidiol may be an efficacious long-term treatment option for treatment-resistant epilepsies.Jul 11, 2018

Artisanal cannabidiol-enriched cannabis may be an effective and safe long-term treatment for refractory epilepsy.Jun 27, 2022

Cannabidiol - an effective analgesic for toothache?May 31, 2024

Cannabidiol acts at 5-HT 1A receptors in the human brain: Relevance for treating temporal lobe epilepsy. Dec 31, 2019

Cannabidiol as a treatment for arthritis and joint pain.Aug 23, 2022

Cannabidiol as an adjuvant treatment in adults with drug-resistant focal epilepsy.Jun 30, 2023

Cannabidiol attenuates insular dysfunction during motivational salience processing in subjects at clinical high risk for psychosis.Aug 21, 2019

Cannabidiol could be useful in Dravet syndrome treatments. Mar 31, 2016

Cannabidiol could reduce severe behavioural problems in children and adolescents with intellectual disability. May 31, 2020

Cannabidiol enhances verbal episodic memory in healthy young participants.Sep 06, 2021

Cannabidiol for moderate-severe insomniaApr 30, 2024

Cannabidiol for rapid eye movement sleep behavior disorder. Mar 21, 2021

Cannabidiol for the treatment of crack-cocaine craving.Oct 29, 2020

Cannabidiol for treating drug-resistant epilepsy in children.Aug 12, 2018

Cannabidiol for treating Lennox-Gastaut Syndrome and Dravet Syndrome in Korea Dec 27, 2020

Cannabidiol has antipsychotic properties which balance out the psychotomimetic effects of THC in cannabis.Apr 01, 2008

Cannabidiol improves frequency and severity of seizures and reduces adverse events.Aug 08, 2018

Cannabidiol improves maternal obesity-induced behavioral, neuroinflammatory and neurochemical dysfunctions in the juvenile offspring.Apr 09, 2024

Cannabidiol in children with treatment-resistant epilepsy with myoclonic-atonic seizures.May 31, 2023

Cannabidiol in the treatment of post-traumatic stress disorder.Dec 12, 2018

Cannabidiol levels in different strains of cannabis may determine the degree to which THC interferes with memory in users.Oct 01, 2010

Cannabidiol may be an effective and well-tolerated treatment option for patients with refractory seizures in Tuberous sclerosis complex.Sep 30, 2016

Cannabidiol may hold benefit for anxiety-related disorders. Dec 31, 2018

Cannabidiol might reduce seizure frequency and might have an adequate safety profile in children and young adults with treatment-resistant epilepsy.Dec 22, 2015

Cannabidiol reduced inflammation and the growth of selected periodontal pathogenic bacteria.May 31, 2024

Cannabidiol reduced the frequency of both focal and generalised seizures with 50 % seizure reduction in 76 % of the cohort.Jun 20, 2024

Cannabidiol reduces anxiety in social anxiety disorder through modulating the limbic and paralimbic brain areas. Sep 09, 2010

Cannabidiol resulted in a greater reduction in convulsive-seizure frequency among patients with Dravet syndrome.Jan 24, 2017

Cannabidiol treatment in children with treatment resistant epilepsies led to 42% of children reporting a greater than 80% reduction in seizure frequency and 32% reporting a 25-60% seizure reduction.Nov 30, 2013

Cannabidiol treatment yielded a significant positive effect on seizure load in patients with intractable epilepsy.Jan 05, 2016

Cannabidiol-enriched oil for adult patients with drug-resistant epilepsy.May 28, 2024

Cannabinoid treatment for autism: a proof-of-concept randomized trial.Feb 02, 2021

Cannabinoids may have therapeutic value in the treatment of tics in Tourette syndrome. Oct 01, 2003

Cannabis and cannabinoids in cancer pain management.May 31, 2020

Cannabis containing equivalent concentrations of delta-9-tetrahydrocannabinol and cannabidiol induces less state anxiety than THC-dominant cannabis.Oct 31, 2022

Cannabis could be potentially beneficial reduction in systemic inflammation and immune activation in the context of antiretroviral-treated HIV infection.Feb 16, 2018

Cannabis extracts can be a useful and safe option for patients with MS with moderate to severe spasticity resistant to common antispastic drugs.May 08, 2016

Cannabis extracts can be considered an alternative in patients with spasticity associated with chronic spinal cord injury.Sep 30, 2017

Cannabis in ASD patients appears to be well tolerated, safe and effective option to relieve symptoms associated with ASD.Jan 16, 2019

Cannabis is well-tolerated and efficacious in the treatment of neuropathic pain from brachial plexus avulsion.Dec 01, 2004

Cannabis may have therapeutic value in the treatment of Tourette syndrome.Dec 01, 1998

Cannabis-based medicine is effective in reducing pain and sleep disturbance in patients with multiple sclerosis related central neuropathic pain and is mostly well tolerated.Sep 27, 2005

Cannabis-based medicine may represent a useful new agent for treatment of the symptomatic relief of spasticity in MS.Feb 28, 2007

CBD can reduce anxiety severity and has an adequate safety profile in young people with treatment-resistant anxiety disorders.Jan 02, 2022

CBD could be beneficial for the treatment of brain tumor-related epilepsy.Oct 23, 2017

CBD enriched hemp oil could be beneficial in girls with adverse drug effects following human papillomavirus (HPV) vaccine.Jan 31, 2017

CBD formulations in patients with temporomandibular disorders have proven to be a successful treatment for reducing pain, muscle tension, and bruxing activity.Feb 28, 2024

CBD has anxiolytic properties in human volunteers submitted to a stressful situation.Dec 31, 1992

CBD is a well supported co-medication and seems to prolong the survival of patients with glioblastoma multiforme.Apr 30, 2021

CBD may be effective, safe and well tolerated for the treatment of the psychosis in Parkinson's disease.Oct 31, 2009

CBD provides symptom relief in patients with gastroparesis and improves the tolerance of liquid nutrient intake.Jul 21, 2023

CBD restores excitability and morphological impairment in epileptic models to pre-epilepsy control levels.Mar 24, 2018

CBD was found to have potential benefits as add-on therapy for refractory childhood epilepsies.Mar 07, 2018

CBD-rich botanical extract may be beneficial for symptomatic treatment of ulcerative colitis.Mar 09, 2018

Chronic pain treatment with cannabidiol in kidney transplant patients in Uruguay.Feb 28, 2018

Cognitive and behavioral effects of cannabidiol in patients with treatment-resistant epilepsy.Nov 23, 2020

Cannabinoids

View the Evidence:
922 Abstracts with Cannabinoids Research