Anthocyanins

Name	AC	CK
Oxidative Stress	74	245
Cardiovascular Diseases	20	185
Inflammation	44	180
Hypertension	10	70
Obesity	28	62
Insulin Resistance	14	57
Cognitive Decline/Dysfunction	7	54
Endothelial Dysfunction	10	48
Atherosclerosis	12	46
Metabolic Syndrome X	10	43
Colorectal Cancer	13	37
Diabetes Mellitus: Type 2	15	37
Colon Cancer	13	36
Hyperglycemia	15	33
Parkinson's Disease	6	33
Dry Eye Syndromes	4	32
C-Reactive Protein	3	30
High Cholesterol	3	30
Stroke	3	30
High Fat Diet	14	28
Nonalcoholic fatty liver disease (NAFLD)	7	28
Alzheimer's Disease	12	26
Diabetes Mellitus: Type 2: Prevention	5	26
Esophageal Cancer	5	26
Hyperuricemia	5	26
Lung Cancer	6	26
Memory Disorders	5	26
Breast Cancer: Triple Negative	3	24
Glaucoma	5	24
Hypercholesterolemia	4	24
Athletic Performance	3	21
Dyslipidemias	3	21
Smoking	2	20
Aging	5	18
Hyperlipidemia	9	18
Inflammatory Bowel Diseases	6	18
Myocardial Infarction	3	15
Chemically-Induced Liver Damage	7	14
Gastric Cancer	4	14
Macular Degeneration	4	14
Aging Skin	3	13
Cancers: All	12	13
Colitis	7	13
Liver Cancer	8	13
Neurodegenerative Diseases	10	13
Chronic Disease	2	12
Endotoxemia	2	12
Lipopolysaccharide-Induced Toxicity	8	12
Bladder Cancer	2	11
Pancreatic Cancer	2	11
Squamous cell carcinoma	2	11
Wound Healing	2	11
Alcoholic Liver Disease	5	10
All-Cause Mortality	1	10
Arterial Hardening: Elasticity	1	10
Athletic Performance: Recovery	1	10
Cardiac Mortality	1	10
Cataract	1	10
Dysbiosis: Bifidobacteria Deficiency	1	10
Endothelial Damage	1	10
Fibrocystic Breast Disease	1	10
Head and Neck Cancer	1	10
Heart Disease	1	10
Menopausal Syndrome	1	10
Muscle Damage: Exercise-Induced	1	10
Myocardial Infarction: Prevention	1	10
Optic Nerve Diseases	1	10
Ovarian Cancer	1	10
Presbyopia	1	10
Sitting Sickness	1	10
Urinary Tract Infections	1	10
Breast Cancer	7	9
DNA damage	7	9
Lipid Peroxidation	5	9
Melanoma	6	9
Diabetes: Oxidative Stress	5	8
Diabetic Complications	6	8
Brain Inflammation	4	7
Cancer Metastasis	4	7
Escherichia coli Infections	7	7
Liver Cancer: Prevention	2	7
Prostate Cancer	5	7
Aging: Brain	3	6
Alcohol Toxicity	3	6
Chemotherapy-Induced Toxicity: Cisplatin	3	6
Diabetic Retinopathy	4	6
Liver Fibrosis	3	6
Male Reproductive Development Abnormalities	3	6
Pseudomonas aeruginosa	6	6
Cadmium Poisoning	3	5
Chemotherapy-Induced Toxicity: Cyclophosphamide	3	5
Copper Toxicity	1	5
Leiomyoma	1	5
Retinal Diseases	3	5
Staphylococcus aureus infection	5	5
Ultraviolet Radiation Induced Damage	4	5
Carcinoma: Non-Small-Cell Lung	3	4
Cervical Cancer	4	4
Chemotherapy	2	4
Chemotherapy-Induced Toxicity: Doxorubicin	2	4
Colorectal Cancer: Prevention	2	4
Diabetic Nephropathy	2	4
Dysbiosis	2	4
Fatty Liver	2	4
Heavy Metal Toxicity	2	4
High Fructose Diet	2	4
High Sugar Diet	2	4
Hydrogen Peroxide Induced Toxicity	2	4
Learning disorders	2	4
Oral Cancer	4	4
Radiation Induced Illness	2	4
Triglycerides: Elevated	3	4
Acrylamide-induced toxicity	2	3
Amyotrophic lateral sclerosis (ALS)	2	3
Depression	2	3
Diabetes	2	3
Eye Damage	2	3
Helicobacter Pylori Infection	1	3
Hepatic Steatosis	2	3
Klebsiella Infections	2	3
Retinal Degeneration: Light-Induced	2	3
Acetaminophen (Tylenol) Toxicity	1	2
Adiponectin: Low Levels	1	2
Aging: Liver	1	2
Air Pollution Linked Toxicity	1	2
Arsenic Poisoning	1	2
Autism Spectrum Disorders	1	2
Blue Light Toxicity	2	2
Brain Injury: Traumatic	1	2
Cancers: Drug Resistant	2	2
Cerebral Ischemia	1	2
Chemotherapy-Induced Toxicity: Gentamicin	1	2
Cholesterol: Oxidation	1	2
Colon Cancer: Prevention	1	2
Diabetes: Cataract	1	2
Encephalopathy	1	2
Estrogen Deficiency	1	2
Fibrosis: Liver	1	2
Fructose-Induced Toxicity	1	2
Gastrointestinal Cancer	1	2
Hyperinsulinism	1	2
Infertility: Male	1	2
Kidney Damage	1	2
Kidney Damage: Chemically-Induced	1	2
Lead Poisoning	1	2
Liver Damage	1	2
Liver Damage: Aflatoxin-Induced	1	2
Liver Injury: Ischemia/reperfusion	1	2
Melanoma: Metastatic	2	2
Memory Impairment: Hormone Deficiency Induced	1	2
Mitochondrial Dysfunction	1	2
Osteoporosis	2	2
Overweight	1	2
Pancreatitis	1	2
Perimenopausal Syndrome	1	2
Sarcomas	1	2
Skin Cancer	1	2
Stroke: Ischemic	1	2
Testicular Injury: Cadmium-Induced	1	2
Testicular Injury: Chemical/Metal Induced	1	2
Thrombus	1	2
Tumors	1	2
Abdominal Obesity (Midsection Fat)	1	1
Acinetobacter baumannii infection	1	1
Acute T cell Leukemias	1	1
Acute lymphoblastic leukemia (ALL)	1	1
Anxiety	1	1
Aspergillosis	1	1
Bacillus Cereus infection	1	1
Bacillus subtilis infections	1	1
Bone Diseases	1	1
Cancers	1	1
Chemotherapy-Induced Toxicity	1	1
Coronavirus Infection	1	1
Coxsackievirus Infections	1	1
Diabetes Mellitus: Type 1	1	1
Dry Skin	1	1
Enterococcus Infections	1	1
Fibrosarcoma	1	1
Galactosemias	1	1
Glioblastoma	1	1
H3N2 Infection	1	1
Herpes Simplex Virus Type 1	1	1
Infertility: Female	1	1
Influenza A	1	1
Leukemia	1	1
Measles	1	1
Melanoma Stem Cell	1	1
Neuroblastoma	1	1
Nicotine/Tobacco Toxicity	1	1
Osteoarthritis	1	1
Salmonella Infections	1	1
Staphylococcal Infections	1	1
Ulcerative Colitis	1	1

Name	AC	CK
Antioxidants	178	486
Anti-Inflammatory Agents	95	266
Neuroprotective Agents	52	164
Cardioprotective	21	142
Hypoglycemic Agents	24	103
Gastrointestinal Agents	29	92
Chemopreventive	20	87
Apoptotic	34	84
Antiproliferative	45	75
Hepatoprotective	32	75
Hypolipidemic	17	74
Anti-metastatic	14	45
NF-kappaB Inhibitor	22	45
Antihypertensive Agents	8	40
Interleukin-6 Downregulation	19	39
Anti-Apoptotic	21	34
Immunomodulatory	8	28
Vasoprotective	4	27
Interleukin-1 beta downregulation	7	24
Tumor Necrosis Factor (TNF) Alpha Inhibitor	15	23
Superoxide Dismutase Up-regulation	8	22
Uricosuric Agents	3	22
Anti-Bacterial Agents	11	21
Anticarcinogenic Agents	10	21
Chemoprotective Agents	11	21
Renoprotective	11	21
Anticholesteremic Agents	6	19
Gastroprotective	5	17
Cell cycle arrest	12	15
Cytoprotective	4	14
Insulin Sensitizers	3	14
Alpha-glucosidase inhibitor	11	13
Cyclooxygenase 2 Inhibitors	8	12
Malondialdehyde Down-regulation	7	12
Nrf2 activation	9	12
Antineoplastic Agents	8	11
Acetylcholinesterase Inhibitor	1	10
Adiponectin upregulation	1	10
Endothelin-1 Inhibitor	1	10
Insulin-Like Growth Factor Inhibition/Downregulation	1	10
Monoamine Oxidase Inhibitors	1	10
Platelet Aggregation Inhibitors	1	10
Vascular Cell Adhesion Molecule-1 Inhibitor	1	10
Alpha-amylase inhibitor	7	7
Anti Inflammatory	2	7
Matrix metalloproteinase-2 (MMP-2) inhibitor	6	7
Matrix metalloproteinase-9 (MMP-9) inhibitor	6	7
Vascular Endothelial Growth Factor Inhibitors	4	7
Vasodilator Agents	2	7
Antimicrobial	6	6
Brain-derived neurotrophic factor modulator	3	6
Chemotherapeutic	5	6
Angiotensin-Converting Enzyme Inhibitors	1	5
Antioxidant Effects	1	5
Genoprotective	3	5
Radioprotective	3	5
Anti-Fibrotic	2	4
Anti-Tumor	2	4
Autophagy Up-regulation	3	4
Heme oxygenase-1 up-regulation	3	4
Photoprotective	4	4
Angiogenesis Inhibitors	3	3
Antidepressive Agents	2	3
Antiviral Agents	3	3
Chemosensitizer	3	3
Enzyme Inhibitors	1	3
Immunostimulatory	2	3
MicroRNA modulator	2	3
Nitric Oxide Inhibitor	2	3
Osteoprotective	3	3
Pancreato Protective Agents	2	3
Anti-Angiogenic	1	2
Anti-Platelet	1	2
Anti-atherogenic	2	2
Autophagy Inhibitors	1	2
Bax/Bcl2 ratio: Increase	1	2
Cytotoxic	2	2
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	1	2
Interleukin-17 downregulation	1	2
Monocyte chemotattractant protein-1 (MCP-1) Inhibitor	1	2
P21 Activation	2	2
Transforming growth factor beta (TGF-β) inhibitor	1	2
Tumor Suppressor Protein p53 Upregulation	2	2
Wnt/β-catenin pathway down-regulation	1	2
apoptosis	1	2
15-Lipoxygenase (15-LOX) Inhibitor	1	1
Anti-Anxiety Agents	1	1
Anti-Glycation Agents	1	1
Anti-Infective Agents	1	1
Anticonvulsants	1	1
Antinoceceptive	1	1
Cardiovascular Agents	1	1
Caspase-9 Activation	1	1
Catalase Up-Regulation	1	1
Cyclin D1 Down-Regulation	1	1
E-cadherin down-regulation	1	1
Enzyme Inhibitors: Pancreatic Amylase	1	1
Fertility Agents: Female	1	1
Interleukin-10 upregulation	1	1
Interleukin-12 downregulation	1	1
Interleukin-2 Downregulation	1	1
Phase II Detoxification Enzyme Inducer	1	1
Regenerative	1	1
Tyrosinase Inhibition	1	1
Vascular Endothelial Growth Factor Regulator	1	1
Vitamin D Receptor (VDR) Modulator	1	1
Wnt/β-catenin signaling pathway modulation	1	1

[+]

Anthocyanins reduce cell Invasion and migration through Akt/mTOR Downregulation and apoptosis activation in triple-negative breast cancer cells.Apr 13, 2023

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Pubmed Data : Cancers (Basel). 2023 Apr 14 ;15(8). Epub 2023 Apr 14. PMID: 37190229

Article Published Date : Apr 13, 2023

Study Type : Meta Analysis, Review

Additional Links

Substances : Anthocyanins

Diseases : Breast Cancer: Triple Negative

Pharmacological Actions : Anti-metastatic, Apoptotic

[+]

Dietary intake of anthocyanins and risk of cardiovascular disease.Dec 31, 2018

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Pubmed Data : Eur J Clin Nutr. 2016 Dec ;70(12):1360-1367. Epub 2016 Aug 17. PMID: 27530472

Article Published Date : Nov 30, 2016

Study Type : Meta Analysis, Review

Additional Links

Substances : Anthocyanins, Berries: All

Diseases : Diabetes Mellitus: Type 2: Prevention

Additional Keywords : Risk Reduction

[+]

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Pubmed Data : J Agric Food Chem. 2010 Dec 8 ;58(23):12130-6. Epub 2010 Nov 10. PMID: 21067240

Article Published Date : Dec 07, 2010

Study Type : Human Study

Additional Links

Substances : Anthocyanins, Chokeberry

Additional Keywords : Bioavailability, Plant Extracts

[+]

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Pubmed Data : Clin Exp Ophthalmol. 2023 Mar ;51(2):122-130. Epub 2023 Feb 3. PMID: 36703096

Article Published Date : Feb 28, 2023

Study Type : Human Study

Additional Links

Substances : Anthocyanins, Grape Seed Extract

Diseases : Dry Eye Syndromes

[+]

Anthocyanin supplementation dose-dependently attenuates platelet function.Jul 31, 2021

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Pubmed Data : EBioMedicine. 2021 Aug ;70:103533. Epub 2021 Aug 12. PMID: 34392146

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Pubmed Data : Food Chem. 2020 Apr 25 ;310:125797. Epub 2019 Oct 26. PMID: 31818516

Article Published Date : Apr 24, 2020

Study Type : Human Study

Additional Links

Substances : Anthocyanins, Sweet Potato: Purple

Diseases : Hyperglycemia, Inflammation

Pharmacological Actions : Hypoglycemic Agents

Additional Keywords : Plant Extracts

[+]

Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : J Int Soc Sports Nutr. 2021 Mar 30 ;18(1):26. Epub 2021 Mar 30. PMID: 33781280

Article Published Date : Mar 29, 2021

Study Type : Human Study

Additional Links

Substances : Anthocyanins, Blueberry

Diseases : Oxidative Stress

Therapeutic Actions : Exercise: Running

Pharmacological Actions : Antioxidants

[+]

Combined anthocyanins and bromelain supplement improves endothelial function and skeletal muscle oxygenation status.Jan 27, 2021

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Pubmed Data : Br J Nutr. 2021 Jan 28 ;125(2):161-171. Epub 2020 Jul 14. PMID: 32660675

Article Published Date : Jan 27, 2021

Study Type : Human Study

Additional Links

Substances : Anthocyanins, Bromelain

Diseases : Endothelial Dysfunction, Hypertension

Pharmacological Actions : Antioxidants

[+]

Consumption of a polyphenol-rich grape-wine extract lowers ambulatory blood pressure in mildly hypertensive subjects.Apr 29, 2015

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Pubmed Data : Nutrients. 2015 Apr 30 ;7(5):3138-53. Epub 2015 Apr 30. PMID: 25942487

Article Published Date : Apr 29, 2015

Study Type : Human Study

Additional Links

Substances : Anthocyanins, Catechin , Polyphenols

Diseases : Hypertension

Pharmacological Actions : Antihypertensive Agents

Additional Keywords : Plant Extracts

[+]

Consumption of an anthocyanin-rich antioxidant juice accelerates recovery of running economy.Sep 22, 2019

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Pubmed Data : Phytother Res. 2023 Mar ;37(3):798-808. Epub 2022 Oct 7. PMID: 36206152

Article Published Date : Feb 28, 2023

Study Type : Human Study

Additional Links

Substances : Anthocyanins

Diseases : Arterial Hardening: Elasticity

Pharmacological Actions : Vasoprotective

[+]

Early intervention in cognitive aging with strawberry supplementation.Oct 18, 2023

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Pubmed Data : Nutrients. 2023 Oct 19 ;15(20). Epub 2023 Oct 19. PMID: 37892506

Article Published Date : Oct 18, 2023

Study Type : Human Study

Additional Links

Substances : Anthocyanins, Strawberry

Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction, Insulin Resistance

Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents

[+]

Effects of wild blueberries on fat oxidation rates in aerobically trained males.Mar 08, 2023

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Pubmed Data : J Med Food. 2012 Sep ;15(9):818-23. Epub 2012 Aug 7. PMID: 22870951

Article Published Date : Aug 31, 2012

Study Type : Human Study

Additional Links

Substances : Anthocyanins, Bilberry, Ginkgo biloba

Diseases : Glaucoma

Pharmacological Actions : Antioxidants

Additional Keywords : Phytotherapy, Plant Extracts

[+]

Greater blueberry intake significantly reduced total age-related macular degeneration.Mar 31, 2024

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Pubmed Data : J Nutr. 2024 Apr ;154(4):1404-1413. Epub 2024 Mar 1. PMID: 38432561

Article Published Date : Mar 31, 2024

Study Type : Human Study

Additional Links

Substances : Anthocyanins

Diseases : Cataract, Macular Degeneration

[+]

High intake of white fruits and vegetables may protect against stroke.Oct 31, 2011

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Pubmed Data : Am J Clin Nutr. 2012 Oct ;96(4):781-8. Epub 2012 Aug 22. PMID: 22914551

Article Published Date : Sep 30, 2012

Study Type : Human Study

Additional Links

Substances : Anthocyanins, Flavonoids

Diseases : Atherosclerosis, Cardiovascular Diseases, Hypertension

Pharmacological Actions : Antihypertensive Agents, Vasoprotective

[+]

Higher intakes of anthocyanins and flavonols and their anti-inflammatory effects may be a key component underlying the reduction in risk of certain chronic diseases.May 26, 2015

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Pubmed Data : Am J Clin Nutr. 2015 May 27. Epub 2015 May 27. PMID: 26016863

Article Published Date : May 26, 2015

Study Type : Human Study

Additional Links

Substances : Anthocyanins, Flavonoids, Fruit: All, Vegetables: All

Diseases : Chronic Disease, Inflammation, Oxidative Stress

Pharmacological Actions : Antioxidants

Additional Keywords : Risk Reduction

[+]

Higher intakes of flavonols and flavanones as well as black tea consumption may be associated with lower risk of ovarian cancer.Oct 31, 2014

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Pubmed Data : Neurology. 2022 Jan 26. Epub 2022 Jan 26. PMID: 35082171

Article Published Date : Jan 25, 2022

Study Type : Human Study

Additional Links

Substances : Anthocyanins, Flavan-3-ols, Flavonoids

Diseases : Parkinson's Disease

Pharmacological Actions : Neuroprotective Agents

[+]

Just three servings weekly of blueberries or strawberries reduced the risk of heart attack in middle aged women by 33% compared to those eating berries once monthly or less in what seems to be an intake dependant manner.Jan 14, 2013

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Pubmed Data : Oxid Med Cell Longev. 2021 ;2021:5520059. Epub 2021 Aug 31. PMID: 34484562

Article Published Date : Dec 31, 2020

Study Type : Human Study

Additional Links

Substances : Anthocyanins

Diseases : Memory Disorders

Pharmacological Actions : Acetylcholinesterase Inhibitor, Monoamine Oxidase Inhibitors, Neuroprotective Agents

Additional Keywords : Plant Extracts

[+]

This study provides further support for a beneficial effect of flavonoid intake on lung cancer riskJul 31, 2008

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Pubmed Data : Int J Cancer. 2008 Aug 1 ;123(3):664-71. PMID: 18491403

Article Published Date : Jul 31, 2008

Study Type : Human Study

Additional Links

Substances : Anthocyanins, Flavonoids, Isoflavones

Diseases : Lung Cancer, Smoking

Pharmacological Actions : Chemopreventive

Additional Keywords : Proanthocyanidins

[+]

Wild blueberry anthocyanins inhibit inflammatory gene expression in vitro.Jul 23, 2014

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Pubmed Data : J Agric Food Chem. 2014 Jul 23 ;62(29):7022-8. Epub 2014 Jan 17. PMID: 24397282

Article Published Date : Jul 23, 2014

Study Type : Human Study

Additional Links

Substances : Anthocyanins

Diseases : Inflammation

[+]

Wild blueberry extract intervention in healthy older adults.Apr 15, 2024

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Pubmed Data : Nutrients. 2024 Apr 16 ;16(8). Epub 2024 Apr 16. PMID: 38674870

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Pubmed Data : J Agric Food Chem. 2014 Aug 20 ;62(33):8346-51. Epub 2014 Aug 8. PMID: 25075866

Article Published Date : Aug 20, 2014

Study Type : Human In Vitro

Additional Links

Substances : Anthocyanins

Diseases : Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, NF-kappaB Inhibitor

Additional Keywords : Plant Extracts

[+]

Additional Keywords : Plant Extracts

[+]

Anthocyanin of black highland barley alleviates H2O2-induced cardiomyocyte injury and myocardial infarction.May 04, 2024

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Pubmed Data : Int J Mol Sci. 2023 Apr 10 ;24(8). Epub 2023 Apr 10. PMID: 37108146

Article Published Date : Apr 09, 2023

Study Type : Animal Study

Additional Links

Substances : Anthocyanins, Sweet Potato: Purple

Diseases : Dry Eye Syndromes, Inflammation

Pharmacological Actions : Antioxidants

[+]

A combination of black bean peel and pomegranate peel extracts, have the ability to ameliorate hyperglycemia by inhibiting oxidative stress induced damage to the pancreas.Dec 31, 2014

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Anthocyanin containing purple fleshed potatoes suppressed colon tumorigenesis via elimination of colon cancer stem cells.Aug 13, 2015

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Pubmed Data : J Nutr Biochem. 2015 Aug 14. Epub 2015 Aug 14. PMID: 26383537

Article Published Date : Aug 13, 2015

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Anthocyanins, Potato: Pigmented

Diseases : Colon Cancer, Colon Cancer: Prevention

Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Apoptotic, Wnt/β-catenin pathway down-regulation

Additional Keywords : Cancer Stem Cells, Natural Substances Versus Drugs, Plant Extracts

Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

[+]

Anthocyanin content in Hibiscus sabdariffa and their antiplatelet and vasorelaxant properties.Apr 28, 2023

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Pubmed Data : Plant Foods Hum Nutr. 2023 Apr 29. Epub 2023 Apr 29. PMID: 37120677

Article Published Date : Apr 28, 2023

Study Type : Animal Study

Additional Links

Substances : Anthocyanins, Hibiscus sabdariffa

Diseases : Thrombus

Pharmacological Actions : Anti-Platelet, Vasodilator Agents

[+]

Anthocyanin enriched sweet potatoes may protect against colorectal cancer by inducing cell-cycle arrest, antiproliferative, and apoptotic mechanisms.Oct 31, 2013

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Pubmed Data : Biomed Pharmacother. 2019 Jun 10 ;117:109087. Epub 2019 Jun 10. PMID: 31195351

Article Published Date : Jun 09, 2019

Study Type : Animal Study

Additional Links

Substances : Anthocyanins, Blue Honeysuckle

Diseases : Alcoholic Liver Disease

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-1 beta downregulation

[+]

Anthocyanin from purple sweet potato attenuates lead-induced reproductive toxicity mediated by JNK signaling pathway in male mice.Aug 23, 2021

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Pubmed Data : J Nutr Biochem. 2011 Jan 7. Epub 2011 Jan 7. PMID: 21216582

Article Published Date : Jan 07, 2011

Study Type : Animal Study

Additional Links

Substances : Anthocyanins, Black Currant

Diseases : Chemically-Induced Liver Damage, Liver Cancer

Pharmacological Actions : Bax/Bcl2 ratio: Increase, Chemopreventive

[+]

Anthocyanin-rich blueberry extracts and anthocyanin metabolite protocatechuic acid promote autophagy-lysosomal pathway and alleviate neurons damage.Dec 31, 2021

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Pubmed Data : Molecules. 2020 Nov 20 ;25(22). Epub 2020 Nov 20. PMID: 33233701

Article Published Date : Nov 19, 2020

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Anthocyanins

Diseases : Liver Cancer

Pharmacological Actions : Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, NF-kappaB Inhibitor

Additional Keywords : Plant Extracts

[+]

Anthocyanins extracted from Portuguese blueberries could constitute an effective strategy to ameliorate typical autistic behaviors.Aug 16, 2022

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Pubmed Data : BMB Rep. 2010 Jan;43(1):46-51. PMID: 16053243

Article Published Date : Jan 01, 2010

Study Type : Animal Study

Additional Links

Substances : Anthocyanins, Blueberry

Diseases : Aging: Brain , Memory Disorders

Pharmacological Actions : Neuroprotective Agents

[+]

Anthocyanins in black raspberries prevent esophageal tumors in rats.Jan 01, 2009

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Pubmed Data : Cancer Prev Res (Phila Pa). 2009 Jan;2(1):84-93. PMID: 19139022

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Pubmed Data : Int J Mol Med. 2018 Mar ;41(3):1608-1618. Epub 2018 Jan 10. PMID: 29328429

Article Published Date : Feb 28, 2018

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Anthocyanins, Grape Seed Extract

Diseases : Diabetes: Oxidative Stress, Diabetic Nephropathy

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Renoprotective

Additional Keywords : Proanthocyanidins

[+]

Anthocyanins prevent the development and progression of urethane-induced lung cancer.Dec 31, 2023

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Pubmed Data : Food Funct. 2021 Dec 13 ;12(24):12647-12658. Epub 2021 Dec 13. PMID: 34821891

Article Published Date : Dec 12, 2021

Study Type : Animal Study

Additional Links

Substances : Anthocyanins, Fermented Foods and Beverages, Sweet Potato: Purple

Diseases : Aging

Pharmacological Actions : Antioxidants

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Anti-hypertensive effects of anthocyanins from Hibiscus sabdarifa.Jun 29, 2022

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Black elderberry may have the potential to influence HDL dysfunction associated with chronic inflammation by impacting hepatic gene expression.Mar 31, 2015

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Pubmed Data : Food Funct. 2015 Apr ;6(4):1278-87. PMID: 25758596

Additional Keywords : Plant Extracts

[+]

Blueberry and blackberry anthocyanins ameliorate metabolic syndrome.Sep 26, 2023

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Pubmed Data : J Agric Food Chem. 2023 Sep 27. Epub 2023 Sep 27. PMID: 37755883

Article Published Date : Sep 26, 2023

Study Type : Animal Study

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Substances : Anthocyanins, Blackberry, Blueberry

Diseases : Metabolic Syndrome X

Pharmacological Actions : Gastrointestinal Agents

[+]

Blueberry and cranberry anthocyanin extracts reduce bodyweight and modulate gut microbiota.Jan 02, 2021

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Pubmed Data : Eur J Nutr. 2021 Jan 3. Epub 2021 Jan 3. PMID: 33392758

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Pubmed Data : Biofactors. 2004 ;21(1-4):259-61. PMID: 15630207

Article Published Date : Dec 31, 2003

Study Type : Animal Study

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Substances : Anthocyanins, Berries: All

Diseases : Chemically-Induced Liver Damage

Pharmacological Actions : Hepatoprotective

Additional Keywords : Phytotherapy

[+]

Chemoprevention of colorectal cancer by black raspberry anthocyanins involved the modulation of gut microbiota and SFRP2 demethylation.Jan 18, 2018

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Pubmed Data : Carcinogenesis. 2018 Jan 19. Epub 2018 Jan 19. PMID: 29361151

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Pubmed Data : Plant Foods Hum Nutr. 2008 Dec ;63(4):176-82. Epub 2008 Aug 23. PMID: 18726160

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Delphinidin-3-sambubioside from Hibiscus sabdariffa. L attenuates hyperlipidemia.Jan 11, 2021

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Pubmed Data : J Oleo Sci. 2014 ;63(3):201-9. Epub 2014 Feb 13. PMID: 24521846

Article Published Date : Jan 01, 2014

Study Type : Animal Study

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Substances : Anthocyanins

Diseases : Hyperglycemia, Hyperlipidemia

Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic

[+]

Dietary anthocyanins mitigate high-fat diet-induced hippocampal inflammation.Jul 22, 2024

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Pubmed Data : Int J Mol Sci. 2022 Sep 20 ;23(19). Epub 2022 Sep 20. PMID: 36232316

Article Published Date : Sep 19, 2022

Study Type : Animal Study

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Substances : Anthocyanins, Bilberry

Diseases : Diabetes Mellitus: Type 2, High Fat Diet, Inflammation, Obesity

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

Additional Keywords : Plant Extracts

[+]

Effect of anthocyanin-rich tart cherry extract on inflammatory mediators and adipokines involved in type 2 diabetes in a high fat diet induced obesity.Aug 20, 2019

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Pubmed Data : Nutrients. 2019 Aug 21 ;11(9). Epub 2019 Aug 21. PMID: 31438590

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Pubmed Data : J Agric Food Chem. 2023 Dec 20 ;71(50):20047-20061. Epub 2023 Dec 12. PMID: 38085678

Article Published Date : Dec 19, 2023

Study Type : Animal Study

Additional Links

Substances : Anthocyanins, Cyanidin 3-glucoside

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Gastrointestinal Agents, Hypoglycemic Agents

[+]

Grape seed extract prevents adverse metabolic alterations through tis anti-inflammatory and antioxidant action.Oct 01, 2017

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Pubmed Data : Phytother Res. 2017 Oct ;31(10):1621-1632. Epub 2017 Aug 25. PMID: 28840618

Article Published Date : Oct 01, 2017

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Pubmed Data : Redox Biol. 2021 10 ;46:102100. Epub 2021 Aug 13. PMID: 34416477

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Pubmed Data : Cancers (Basel). 2016 ;8(3). Epub 2016 Feb 26. PMID: 26927179

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Pubmed Data : Behav Brain Res. 2008 Dec 1;194(1):100-7. Epub 2008 Jul 4. PMID: 18652848

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Pubmed Data : Molecules. 2021 Apr 16 ;26(8). Epub 2021 Apr 16. PMID: 33923467

Article Published Date : Apr 15, 2021

Study Type : Animal Study

Additional Links

Substances : Anthocyanins, Raspberry

Diseases : Alcoholic Liver Disease

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Hepatoprotective

[+]

Natural polyphenols extracted from S. nigra and A. melanocarpa modulate specific and non-specific immune defences in insulin-deficiency diabetes.Mar 31, 2015

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Pubmed Data : Pharm Biol. 2015 Apr ;53(4):533-9. Epub 2014 Oct 20. PMID: 25327310

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Pubmed Data : Eur J Nutr. 2019 Nov 7. Epub 2019 Nov 7. PMID: 31696323

Article Published Date : Nov 06, 2019

Study Type : Animal Study

Additional Links

Substances : Anthocyanins, Strawberry

Diseases : Inflammatory Bowel Diseases, Metabolic Syndrome X

Pharmacological Actions : Anti-Inflammatory Agents, Antihypertensive Agents, Cardioprotective, Hepatoprotective

[+]

[+]

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Pubmed Data : J Nat Med. 2015 Oct 19. Epub 2015 Oct 19. PMID: 26481011

Article Published Date : Oct 18, 2015

Study Type : Animal Study

Additional Links

Substances : Anthocyanins, Sweet Potato: Purple

Diseases : Alcohol Toxicity , Alcoholic Liver Disease

Pharmacological Actions : Antioxidants, Hepatoprotective

[+]

Purple rice bran extract exhibited cancer chemopreventive effects on the aflatoxin B1induced initiation stage of hepatocarcinogenesis in ratsDec 31, 2014

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Pubmed Data : Asian Pac J Cancer Prev. 2015 ;16(8):3371-6. PMID: 25921147

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Pubmed Data : Oncotarget. 2017 Nov 14 ;8(57):96761-96773. Epub 2017 May 12. PMID: 29228569

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Pubmed Data : PLoS One. 2016 ;11(2):e0149081. Epub 2016 Feb 16. PMID: 26882456

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Anthocyanins, Strawberry

Pharmacological Actions : Gastrointestinal Agents

Additional Keywords : Plant Extracts

[+]

Strawberry methanolic extract attenuates Alzheimer's beta amyloid production and oxidative stress.Sep 30, 2021

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Pubmed Data : J Agric Food Chem. 2022 Jan 19. Epub 2022 Jan 19. PMID: 35044756

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Pubmed Data : Biochimie. 2020 Jan ;168:10-16. Epub 2019 Oct 25. PMID: 31669604

Article Published Date : Dec 31, 2019

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Pubmed Data : Biofactors. 2015 Jan-Feb;41(1):58-65. PMID: 25728636

Article Published Date : Dec 31, 2014

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Anthocyanins, Hibiscus sabdariffa

Diseases : Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Monocyte chemotattractant protein-1 (MCP-1) Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

The results suggest that aronia fruit extract could protect the retina.Dec 08, 2021

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View the Evidence: 490 Abstracts with Anthocyanins Research

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Anthocyanins reduce cell Invasion and migration through Akt/mTOR Downregulation and apoptosis activation in triple-negative breast cancer cells.Apr 13, 2023

Dietary intake of anthocyanins and risk of cardiovascular disease.Dec 31, 2018

How effective are anthocyanins on healthy modification of cardiometabolic risk factors.May 22, 2023

This meta-analysis showed that tart cherry juice mostly had a favorable effect on fasting blood sugar levels.Nov 30, 2022

Anthocyanin consumption and risk of colorectal cancer.Jun 30, 2019

Anthocyanin rich foods or extracts may improve vascular health.Aug 19, 2017

Higher dietary intakes of anthocyanins and berry fruits are associated with a lower T2DM risk.Nov 30, 2016

Results indicate that consumption of whole fruit high in anthocyanins can be beneficial for reducing inflammation and oxidative stress.Jun 21, 2019

The present systematic review suggests that the dietary intakes of six classes of flavonoids significantly decrease the risk of cardiovascular diseases.Jan 13, 2014

A 12-week supplement of purified anthocyanin improved insulin resistance, indicators of liver injury, and clinical evolution in NAFLD patients. Apr 30, 2015

A higher dietary intake of anthocyanins was associated with an attenuation of lung function decline.Jan 31, 2016

A prebiotic and anthocyanin blend improved gastrointestinal health and impacted skin status in humans.May 31, 2019

A red-fleshed apple rich in anthocyanins improves endothelial function, reduces inflammation, and modulates the immune system in hypercholesterolemic subjects.Jun 03, 2024

Acute ingestion of a single dose of blackcurrant extract maintained forearm blood flow and forearm vascular resistance during an extended period of sitting.Dec 31, 2019

Administration of 240 mg of anthocyanins a day for 30 days caused a substantial increase of glutathione peroxidase and catalase activities. While decreasing the lead, aluminum and cooper concentrations.Oct 31, 2005

After consumption of a dietary-relevant dose of anthocyanins as natural chokeberry juice, anthocyanins and their metabolites were present in plasma and urine of volunteers.Dec 07, 2010

An anthocyanin mixture reduced the inflammatory response in hypercholesterolemic subjects.Aug 31, 2013

An anthocyanin-rich blackcurrant extract prior to exercise may assist recovery from oxidative stress and maintains circulating neutrophil function.Dec 31, 2018

Anthaplex improves cognitive function and eye dryness via the modulations of the histone acetylation process, gut microbiome, and cholinergic function.Aug 07, 2023

Anthocyanin complex niosome gel accelerates oral wound healing.Jan 09, 2021

Anthocyanin intake is associated with improved memory in older adults with mild cognitive impairment.Dec 31, 2021

Anthocyanin oligomer (grape skin extract) administration improves dry eye disease.Feb 28, 2023

Anthocyanin supplementation dose-dependently attenuates platelet function.Jul 31, 2021

Anthocyanin supplementation exerts beneficial metabolic effects in subjects with type 2 diabetes by improving dyslipidemia, enhancing antioxidant capacity, and preventing insulin resistance.Mar 31, 2015

Anthocyanin-rich apples may influence immune function compared to control apples.Mar 26, 2021

Anthocyanin-rich extract from purple potatoes decreases postprandial glycemic response and affects inflammation markers in healthy men.Apr 24, 2020

Anthocyanins in berries exhibited anti-atherogenicity and antiplatelet activities in a metabolic syndrome population.Dec 31, 2019

Anthocyanins may reduce cardiovascular risk associated with endothelial dysfunction and inflammatory responses to a typical high fat 'Western' meal.Dec 31, 2020

Antiaging, brightening, and antioxidant efficacy of fermented bilberry extract.Jul 09, 2024

Aronia berry polyphenol consumption reduces plasma total and low-density lipoprotein cholesterolDec 31, 2016

Association between dietary intake of flavonoids and hyperuricemia.Jun 23, 2023

Bilberry (myrtillus) anthocyanins improve the symptoms of fibrocystic breast disease. Dec 01, 1993

Bilberry extract can improve tear secretion and plasmatic antioxidant potential in subjects suffering from dry eye disease symptoms.Dec 31, 2016

Bioavailability of bioactive compounds in Hibiscus sabdariffa beverage as a potential anti-inflammatory.Nov 30, 2023

Black chokeberry juice lowered the incidence of Urinary tract infections by 55% and a reduction in antibiotics use in patients. May 31, 2014

Black currant anthocyanins caused a normalization of serum levels of ET-1 and may slow down glaucoma progression.May 31, 2013

Blackcurrant anthocyanin could attenuate the smoking-induced acute endothelial dysfunction and improve peripheral temperature in young smokers.Nov 24, 2019

Blackcurrant anthocyanins has the potential to be developed to treat neurological conditions with IGF-1 deficiency.Jun 01, 2018

Blackcurrant anthocyanins improve blood lipids and biomarkers of inflammation and oxidative stress.Oct 18, 2023

Blueberry anthocyanin intake attenuates the postprandial cardiometabolic effect of an energy-dense food challenge.Dec 31, 2021

Blueberry intake elevates post-exercise anti-inflammatory oxylipins.Jul 23, 2023

Blueberry supplementation reduces the blood lactate response to running in normobaric hypoxia.Mar 29, 2021

Combined anthocyanins and bromelain supplement improves endothelial function and skeletal muscle oxygenation status.Jan 27, 2021

Consumption of a polyphenol-rich grape-wine extract lowers ambulatory blood pressure in mildly hypertensive subjects.Apr 29, 2015

Consumption of an anthocyanin-rich antioxidant juice accelerates recovery of running economy.Sep 22, 2019

Cyanidin and delphinidin exerted beneficial actions against unhealthy diets.Apr 30, 2022

Daily consumption of an anthocyanin-rich extract made from New Zealand blackcurrants for 5 weeks supports exercise recovery.Dec 31, 2019

Daily intake of anthocyanin-rich New Zealand blackcurrant extract alters substrate oxidation during moderate-intensity. Oct 28, 2020

Dietary anthocyanin is associated with a lower prevalence of hyperuricemia.Apr 30, 2024

Dietary intake of anthocyanins improves arterial stiffness.Feb 28, 2023

Early intervention in cognitive aging with strawberry supplementation.Oct 18, 2023

Effects of wild blueberries on fat oxidation rates in aerobically trained males.Mar 08, 2023

Extract from Aronia melanocarpa, Lonicera caerulea, and Vaccinium myrtillus improves near visual acuity in people with presbyopia.Mar 22, 2024

Flavonoid consumption reduces the risk of esophageal cancer.Jun 01, 2007

Fresh cabbage consumption in volunteer’s showed a higher antioxidant capacity than after fermented cabbage intake.Dec 31, 2015

Ginkgo biloba extract and bilberry anthocyanins improve visual function in patients with normal tension glaucoma.Aug 31, 2012

Greater blueberry intake significantly reduced total age-related macular degeneration.Mar 31, 2024

High intake of white fruits and vegetables may protect against stroke.Oct 31, 2011

High levels of Bifidobacteria are associated with increased levels of anthocyanin microbial metabolites.Jul 31, 2014

Higher anthocyanin intake is associated with a lower risk of non-alcoholic fatty liver disease.Dec 31, 2022

Higher anthocyanin intake is associated with lower arterial stiffness and central blood pressure in women.Sep 30, 2012

Higher intakes of anthocyanins and flavonols and their anti-inflammatory effects may be a key component underlying the reduction in risk of certain chronic diseases.May 26, 2015

Higher intakes of flavonols and flavanones as well as black tea consumption may be associated with lower risk of ovarian cancer.Oct 31, 2014

Higher intakes of fruit-based flavonoids were associated with a lower risk of nonfatal MI and ischemic stroke in men.Aug 02, 2016

Improvements in delayed recall found in this pilot study suggest that, following acute flavonoid-rich blueberry drink helped school-aged children encode memory items more effectively.Feb 28, 2015

In this study the intake of anthocyanidins was associated with a 57% reduction in the risk of incident oesophageal and gastric cancers.Dec 31, 2014

Intake duration of Anthocyanin-rich new Zealand blackcurrant extract affects metabolic responses during moderate intensity walking exercise.Jun 23, 2020

Intake of flavonoids and flavonoid-rich foods, and mortality risk among individuals with Parkinson disease.Jan 25, 2022

Just three servings weekly of blueberries or strawberries reduced the risk of heart attack in middle aged women by 33% compared to those eating berries once monthly or less in what seems to be an intake dependant manner.Jan 14, 2013

Neurocognitive effects of cocoa and red-berries consumption in healthy adults.Dec 20, 2021

Plasma anthocyanins and their metabolites reduce in vitro migration of pancreatic cancer cells.Jan 31, 2023

Potential of anthocyanin as an anti-inflammatory agent.Feb 28, 2021

Anthocyanins

View the Evidence:
490 Abstracts with Anthocyanins Research