Anxiolytic

Name	AC	CK
Kava Kava	7	74
Lavender	4	34
Chamomile	3	30
Arginine	2	20
Ayahuasca	1	20
Lavender: Essential Oil	2	20
Lysine	2	20
Psilocybin	1	20
Rose	1	20
Valerian	3	14
Magnolia	3	13
Gotu Kola	2	12
Melissa (Lemonbalm)	2	12
Cannabidiol	2	11
Ayurvedic Formulations	1	10
Bach Flower Remedies	1	10
Cannabis	1	10
Echium amoenum	1	10
Gourd	1	10
Lion's Mane (Hericium Erinaceus)	1	10
Lysergic Acid Diethylamide (LSD)	1	10
Melatonin	1	10
Motherwort	1	10
Passion Flower	1	10
Phellodendron	1	10
Pumpkin Seed Oil/Meal	1	10
Rhodiola (Tibetan Ginseng)	1	10
Skullcap: Blue	1	10
Sweet Orange	1	10
Tryptophan	1	10
Angelica	2	4
Astaxanthin	1	2
Bifidobacterium Longum	1	2
Black Pepper	1	2
Curcumin	1	2
DHA (Docosahexaenoic Acid)	1	2
Damiana	1	2
Echinacea	1	2
Fish Oil	1	2
Homeopathic Treatment: Pulsatilla nigricans	1	2
Horsetail	1	2
Lemon	1	2
Linden (Tilia)	1	2
Lotus	1	2
Luteolin	1	2
Neem	1	2
Progesterone	1	2
Salvia divinorum	1	2
Scopoletin	1	2
Theanine	1	2
Noni	1	1
Ziziphus spinosa	1	1

[+]

Kava Kava appears to be a short-term treatment for anxiety, but not a replacement for prolonged anti-anxiety use. Oct 31, 2018

Click here to read the entire abstract

Pubmed Data : Complement Ther Clin Pract. 2018 Nov ;33:107-117. Epub 2018 Sep 15. PMID: 30396607

Article Published Date : Oct 31, 2018

Study Type : Meta Analysis, Review

Additional Links

Substances : Kava Kava

Diseases : Anxiety Disorders

Pharmacological Actions : Anxiolytic

Additional Keywords : Plant Extracts

[+]

Lavender and rose oil aromatherapy has been determined to have anti-anxiety activity.Jan 01, 2010

Click here to read the entire abstract

Pubmed Data : Rev Neurosci. 2010;21(2):141-52. PMID: 20614803

Article Published Date : Jan 01, 2010

Study Type : Meta Analysis

Additional Links

Substances : Lavender, Rose

Diseases : Anxiety Disorders, Generalized Anxiety Disorder

Therapeutic Actions : Aromatherapy

Pharmacological Actions : Anxiolytic

[+]

Systematic review: psychedelics appear to be effective in significantly reducing symptoms of depression and anxiety and are well-tolerated.Jul 29, 2019

Click here to read the entire abstract

Pubmed Data : J Affect Disord. 2019 Jul 30 ;258:11-24. Epub 2019 Jul 30. PMID: 31382100

Article Published Date : Jul 29, 2019

Study Type : Meta Analysis

Additional Links

Substances : Ayahuasca, Psilocybin

Diseases : Depression

Pharmacological Actions : Antidepressive Agents, Anxiolytic

[+]

The current weight of evidence supports the use of kava in treatment of anxiety with a significant result occurring in four out of six studies reviewed.Jan 01, 2011

Click here to read the entire abstract

Pubmed Data : Aust N Z J Psychiatry. 2011 Jan;45(1):27-35. Epub 2010 Nov 15. PMID: 21073405

Article Published Date : Jan 01, 2011

Study Type : Meta Analysis

Additional Links

Substances : Kava Kava

Diseases : Anxiety Disorders

Pharmacological Actions : Anxiolytic

[+]

This meta-analysis showed a significant improvement in sleep quality and generalized anxiety disorder.Jun 01, 2019

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2019 Jun ;33(6):1604-1615. Epub 2019 Apr 21. PMID: 31006899

Article Published Date : Jun 01, 2019

Study Type : Meta Analysis

Additional Links

Diseases : Anxiety Disorders, Sleep Disorders

Pharmacological Actions : Anxiolytic

[+]

432 Hz Music has an anxiolytic effect in the treatment of endodontic treatment.Aug 31, 2016

Click here to read the entire abstract

Pubmed Data : J Endod. 2016 Sep ;42(9):1338-43. Epub 2016 Jul 16. PMID: 27430941

Article Published Date : Aug 31, 2016

Study Type : Human Study

Additional Links

Diseases : Anxiety, Root Canal Therapy

Therapeutic Actions : Music

Pharmacological Actions : Anxiolytic

Anti Therapeutic Actions : Dental Interventions, Root Canal

[+]

A combination of Magnolia and Phellodendron reduces symptoms of stress and anxiety in premenopausal women.Sep 01, 2005

Click here to read the entire abstract

Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2005 Sep;14(9):2098-105. PMID: 18426577

Article Published Date : Sep 01, 2005

Study Type : Human Study

Additional Links

Substances : Magnolia, Phellodendron

Diseases : Anxiety Disorders, Premenopausal Disorders, Stress

Pharmacological Actions : Anxiolytic

Additional Keywords : Plant Extracts

[+]

Bach flower remedies appear to reduce anxiety in human subjects.Jul 01, 2001

Click here to read the entire abstract

Pubmed Data : J Anxiety Disord. 2001 Jul-Aug;15(4):359-66. PMID: 11474820

Article Published Date : Jul 01, 2001

Study Type : Human Study

Additional Links

Substances : Bach Flower Remedies

Diseases : Anxiety Disorders

Pharmacological Actions : Anxiolytic

Additional Keywords : Plant Extracts

[+]

Blue skullcap (S. lateriflora) demonstates anti-anxiety activity in human subjects. Mar 01, 2003

Click here to read the entire abstract

Pubmed Data : Altern Ther Health Med. 2003 Mar-Apr;9(2):74-8. PMID: 12652886

Article Published Date : Mar 01, 2003

Study Type : Human Study

Additional Links

Substances : Skullcap: Blue

Diseases : Anxiety Disorders

Pharmacological Actions : Anxiolytic

[+]

Cannabidiol reduces anxiety in social anxiety disorder through modulating the limbic and paralimbic brain areas. Sep 09, 2010

Click here to read the entire abstract

Pubmed Data : J Psychopharmacol. 2010 Sep 9. Epub 2010 Sep 9. PMID: 20829306

Article Published Date : Sep 09, 2010

Study Type : Human Study

Additional Links

Substances : Cannabidiol, Cannabis

Diseases : Anxiety Disorders, Social Anxiety Disorder (SAD)

Pharmacological Actions : Anxiolytic

[+]

Chamomile extract has a positive effect in reducing symptoms in patients with generalized anxiety disorder. Aug 01, 2009

Click here to read the entire abstract

Pubmed Data : J Clin Psychopharmacol. 2009 Aug;29(4):378-82. PMID: 19593179

Article Published Date : Aug 01, 2009

Study Type : Human Study

Additional Links

Substances : Chamomile

Diseases : Anxiety: Generalized, Anxiety Disorders

Pharmacological Actions : Anxiolytic

[+]

Chamomile improves cortisol patterns in subjects with moderate to severe generalized anxiety disorder.Jan 01, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Psychiatr Res. 2018 01 ;96:189-195. Epub 2017 Oct 16. PMID: 29080520

Article Published Date : Jan 01, 2018

Study Type : Human Study

Additional Links

Substances : Chamomile

Diseases : Anxiety Disorders

Pharmacological Actions : Anxiolytic

Additional Keywords : Phytotherapy, Plant Extracts

[+]

Chamomile may provide clinically meaningful antidepressant activity that occurs in addition to its previously observed anxiolytic activity.Aug 31, 2012

Click here to read the entire abstract

Pubmed Data : Altern Ther Health Med. 2012 Sep-Oct;18(5):44-9. PMID: 22894890

Article Published Date : Aug 31, 2012

Study Type : Human Study

Additional Links

Substances : Chamomile

Diseases : Anxiety Disorders, Depression

Pharmacological Actions : Antidepressive Agents, Anxiolytic

Additional Keywords : Phytotherapy, Plant Extracts

[+]

Clinical efficacy of Manasamitra Vataka (an Ayurveda medication) on generalized anxiety disorder with comorbid generalized social phobia: a randomized controlled study.May 31, 2012

Click here to read the entire abstract

Pubmed Data : J Altern Complement Med. 2012 Jun ;18(6):612-21. PMID: 22784349

Article Published Date : May 31, 2012

Study Type : Human Study

Additional Links

Substances : Ayurvedic Formulations

Diseases : Anxiety Disorders

Therapeutic Actions : Ayurvedic Medicine

Pharmacological Actions : Anxiolytic

Additional Keywords : Phytotherapy, Plant Extracts, Superiority of Natural Substances versus Drugs

Problem Substances : Benzodiazepines, Clonazepam

[+]

Echium amoenum may have therapeutic value in the treatment of obessive-compulsive disorder.Dec 01, 2006

Click here to read the entire abstract

Pubmed Data : Integr Cancer Ther. 2006 Dec;5(4):362-72. PMID: 19737592

Article Published Date : Dec 01, 2006

Study Type : Human Study

Additional Links

Substances : Echium amoenum

Diseases : Obsessive-Compulsive Disorder

Pharmacological Actions : Anxiolytic

[+]

EFT results in reduced psychological stress and cortisol in human subjects.Sep 30, 2012

Click here to read the entire abstract

Pubmed Data : J Nerv Ment Dis. 2012 Oct ;200(10):891-6. PMID: 22986277

Article Published Date : Sep 30, 2012

Study Type : Human Study

Additional Links

Diseases : Anxiety Disorders, Cortisol: High

Therapeutic Actions : Emotional Freedom Technique

Pharmacological Actions : Anxiolytic

[+]

Emotional freedom techniques improves multiple physiological markers of health.Dec 31, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Evid Based Integr Med. 2019 Jan-Dec;24:2515690X18823691. PMID: 30777453

Article Published Date : Dec 31, 2018

Study Type : Human Study

Additional Links

Diseases : Anxiety, Post-Traumatic Stress Disorders (PTSD)

Therapeutic Actions : Emotional Freedom Technique

Pharmacological Actions : Antihypertensive Agents, Anxiolytic

[+]

Emotional Freedom Techniques show promise as feasible treatments for test anxiety.Oct 31, 2009

Click here to read the entire abstract

Pubmed Data : Explore (NY). 2009 Nov-Dec;5(6):338-40. PMID: 19913760

Article Published Date : Oct 31, 2009

Study Type : Human Study

Additional Links

Diseases : Anxiety Disorders

Therapeutic Actions : Emotional Freedom Technique

Pharmacological Actions : Anxiolytic

[+]

Gotu kola may have therapeutic efficacy in the treatment of anxiety syndromes.Dec 01, 2000

Click here to read the entire abstract

Pubmed Data : J Clin Psychopharmacol. 2000 Dec;20(6):680-4. PMID: 11106141

Article Published Date : Dec 01, 2000

Study Type : Human Study

Additional Links

Substances : Gotu Kola

Diseases : Anxiety Disorders

Pharmacological Actions : Anxiolytic

[+]

Hericium erinaceus intake results in a reduction of depression and anxiety in mice by 4 weeks. Aug 01, 2010

Click here to read the entire abstract

Pubmed Data : Biomed Res. 2010 Aug ;31(4):231-7. PMID: 20834180

Article Published Date : Aug 01, 2010

Study Type : Human Study

Additional Links

Substances : Lion's Mane (Hericium Erinaceus)

Diseases : Anxiety Disorders, Depression

Pharmacological Actions : Anxiolytic

[+]

Kava is safe and effective in treating anxiety disorders and depression.Aug 01, 2009

Click here to read the entire abstract

Pubmed Data : Psychopharmacology (Berl). 2009 Aug;205(3):399-407. Epub 2009 May 9. PMID: 19430766

Article Published Date : Aug 01, 2009

Study Type : Human Study

Additional Links

Substances : Kava Kava

Diseases : Anxiety Disorders, Depression

Pharmacological Actions : Antidepressive Agents, Anxiolytic

Additional Keywords : Plant Extracts

[+]

Kava was judged to be an effective and safe treatment of non-psychotic anxiety syndrome.Apr 01, 2004

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2004 Apr;18(4):297-300. PMID: 15162364

Article Published Date : Apr 01, 2004

Study Type : Human Study

Additional Links

Substances : Kava Kava

Diseases : Anxiety Disorders

Pharmacological Actions : Anxiolytic

[+]

Kava was judged to improve the mood, particularly by reducing anxiety in perimenopausal women.Dec 01, 2008

Click here to read the entire abstract

Pubmed Data : Integr Cancer Ther. 2008 Dec;7(4):295-310. PMID: 12590005

Article Published Date : Dec 01, 2008

Study Type : Human Study

Additional Links

Substances : Kava Kava

Diseases : Anxiety Disorders, Perimenopausal Syndrome

Pharmacological Actions : Anxiolytic

[+]

Lavender essence has a positive effect on anxiety and blood cortisol level among patients about to undergo open heart surgery. Jun 30, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Iran J Nurs Midwifery Res. 2016 Jul-Aug;21(4):397-401. PMID: 27563324

Article Published Date : Jun 30, 2016

Study Type : Human Study

Additional Links

Substances : Lavender: Essential Oil

Diseases : Anxiety Disorders, Cortisol: High

Pharmacological Actions : Anxiolytic

[+]

LSD can reduce anxiety.Mar 02, 2014

Click here to read the entire abstract

Pubmed Data : J Nerv Ment Dis. 2014 Mar 3. Epub 2014 Mar 3. PMID: 24594678

Article Published Date : Mar 02, 2014

Study Type : Human Study

Additional Links

Substances : Lysergic Acid Diethylamide (LSD)

Diseases : Anxiety Disorders

Pharmacological Actions : Anxiolytic

[+]

Melatonin and to a lesser degree mothewort decrease retinal sensitivity and improves the emotional state in anxious young subjects.Nov 01, 2006

Click here to read the entire abstract

Pubmed Data : Eksp Klin Farmakol. 2006 Nov-Dec;69(6):17-9. PMID: 17209457

Article Published Date : Nov 01, 2006

Study Type : Human Study

Additional Links

Substances : Melatonin

Diseases : Anxiety Disorders, Retinal Diseases, Retinal Sensitivity

Pharmacological Actions : Anxiolytic

Additional Keywords : Plant Extracts

[+]

Melissa officinalis and Valeriana officinalis have an anti-anxiety effect during laboratory-induced stress. Feb 01, 2006

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2006 Feb;20(2):96-102. PMID: 16444660

Article Published Date : Feb 01, 2006

Study Type : Human Study

Additional Links

Substances : Melissa (Lemonbalm), Valerian

Diseases : Anxiety Disorders, Stress

Pharmacological Actions : Anxiolytic

Additional Keywords : Plant Extracts

[+]

Motherwort improves symptoms of anxiety and depression in patients with arterial hypertension.Apr 01, 2011

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2011 Apr;25(4):540-3. Epub 2010 Sep 13. PMID: 20839214

Article Published Date : Apr 01, 2011

Study Type : Human Study

Additional Links

Substances : Motherwort

Diseases : Anxiety Disorders, Depression, Hypertension

Pharmacological Actions : Antidepressive Agents, Anxiolytic

[+]

Oral treatment with L-lysine and L-arginine reduces anxiety and basal cortisol levels in healthy humans.Apr 01, 2007

Click here to read the entire abstract

Pubmed Data : Biomed Res. 2007 Apr;28(2):85-90. PMID: 17510493

Article Published Date : Apr 01, 2007

Study Type : Human Study

Additional Links

Substances : Arginine, Lysine

Diseases : Anxiety Disorders, Cortisol: High

Pharmacological Actions : Anxiolytic

[+]

Passionflower as a premedication reduces anxiety without inducing sedation.Jun 01, 2008

Click here to read the entire abstract

Pubmed Data : Anesth Analg. 2008 Jun;106(6):1728-32. PMID: 18499602

Article Published Date : Jun 01, 2008

Study Type : Human Study

Additional Links

Substances : Passion Flower

Diseases : Anxiety: Preoperative, Anxiety Disorders

Pharmacological Actions : Anxiolytic

[+]

Rhodiola rosea significantly improves generalized anxiety disorder (GAD)Mar 01, 2008

Click here to read the entire abstract

Pubmed Data : J Altern Complement Med. 2008 Mar;14(2):175-80. PMID: 18307390

Article Published Date : Mar 01, 2008

Study Type : Human Study

Additional Links

Substances : Rhodiola (Tibetan Ginseng)

Diseases : Anxiety Disorders

Pharmacological Actions : Anxiolytic

[+]

Silexan, an orally administered Lavandula oil preparation, is effective in the treatment of 'subsyndromal' anxiety disorder.Aug 31, 2010

Click here to read the entire abstract

Pubmed Data : Int Clin Psychopharmacol. 2010 Sep ;25(5):277-87. PMID: 20512042

Article Published Date : Aug 31, 2010

Study Type : Human Study

Additional Links

Substances : Lavender

Diseases : Anxiety Disorders

Pharmacological Actions : Anxiolytic

Additional Keywords : Phytotherapy

[+]

Subchronic treatment with amino acid mixture of L-lysine and L-arginine may have ameliorative value during psychosocial stress.Jun 01, 2005

Click here to read the entire abstract

Pubmed Data : Nutr Neurosci. 2005 Jun;8(3):155-60. PMID: 16117182

Article Published Date : Jun 01, 2005

Study Type : Human Study

Additional Links

Substances : Arginine, Lysine

Diseases : Anxiety Disorders

Pharmacological Actions : Anxiolytic

[+]

Sweet orange essential oil has anti-anxiety properties.Jul 31, 2012

Click here to read the entire abstract

Pubmed Data : J Altern Complement Med. 2012 Aug ;18(8):798-804. Epub 2012 Jul 31. PMID: 22849536

Article Published Date : Jul 31, 2012

Study Type : Human Study

Additional Links

Substances : Sweet Orange

Diseases : Anxiety Disorders

Therapeutic Actions : Aromatherapy

Pharmacological Actions : Anxiolytic

Additional Keywords : Plant Extracts

[+]

The inhalation of lavender oil has stress reducing effects. Mar 31, 2012

Click here to read the entire abstract

Pubmed Data : J Med Assoc Thai. 2012 Apr ;95(4):598-606. PMID: 22612017

Article Published Date : Mar 31, 2012

Study Type : Human Study

Additional Links

Substances : Lavender: Essential Oil

Diseases : Stress and Anxiety

Therapeutic Actions : Aromatherapy

Pharmacological Actions : Anxiolytic

[+]

The practice of asanas and yoga decreased anxiety in women.Jan 16, 2014

Click here to read the entire abstract

Pubmed Data : West Indian Med J. 2014 Jan 17 ;63(1):83-85. Epub 2014 Jan 17. PMID: 25303199

Article Published Date : Jan 16, 2014

Study Type : Human Study

Additional Links

Diseases : Anxiety Disorders, Anxiety States: Neurotic, Stress and Anxiety

Therapeutic Actions : Yoga

Pharmacological Actions : Anxiolytic

[+]

Tryptophan-rich gourd seeds are a potential anxiolytic to those suffering from social phobia.Sep 01, 2007

Click here to read the entire abstract

Pubmed Data : Can J Physiol Pharmacol. 2007 Sep;85(9):928-32. PMID: 18066139

Article Published Date : Sep 01, 2007

Study Type : Human Study

Additional Links

Substances : Gourd, Pumpkin Seed Oil/Meal, Tryptophan

Diseases : Anti-Social Behavior, Anxiety Disorders, Phobia: Social

Pharmacological Actions : Anxiolytic

[+]

A methanolic extract of Piper nigrum ameliorates beta-amyloid (1–42)-induced anxiety and depression by attenuation of the oxidative stress in the rat amygdala.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Behav Brain Funct. 2015 ;11:13. Epub 2015 Mar 29. PMID: 25880991

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Substances : Black Pepper

Diseases : Alzheimer's Disease, Anxiety Disorders, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Anxiolytic, Neuroprotective Agents

Additional Keywords : Plant Extracts

[+]

Amelioration of age-related cognitive decline and anxiety in mice by Centella asiatica extract varies by sex, dose and mode of administration.Dec 31, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Aging. 2024 ;5:1357922. Epub 2024 May 6. PMID: 38770167

Article Published Date : Dec 31, 2023

Study Type : Animal Study

Additional Links

Substances : Gotu Kola

Diseases : Anxiety, Cognitive Decline/Dysfunction

Pharmacological Actions : Anxiolytic, Neuroprotective Agents

[+]

Angelica root coumarins display synergistic anxiolytic activity.Jan 10, 2013

Click here to read the entire abstract

Pubmed Data : Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jan 10 ;40:180-6. Epub 2012 Aug 29. PMID: 22960104

Article Published Date : Jan 10, 2013

Study Type : Animal Study

Additional Links

Substances : Angelica

Diseases : Anxiety Disorders

Pharmacological Actions : Anxiolytic

Additional Keywords : Plant Extracts

[+]

Angelica whole plant and leaf display the highest anxiolytic activity whereas the root, fruit, intermediate, and stem display the least.Jul 01, 2012

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Tradit Complement Med. 2012 Jul ;2(3):235-41. PMID: 24716138

Article Published Date : Jul 01, 2012

Study Type : Animal Study

Additional Links

Substances : Angelica

Diseases : Anxiety

Pharmacological Actions : Anxiolytic

[+]

Astaxanthin prevents fish-oil induced oxidative stress in the anterior forebrain of animals, resulting in an anxiety reducing effect. May 17, 2011

Click here to read the entire abstract

Pubmed Data : Pharmacol Biochem Behav. 2011 May 17;99(3):349-355. Epub 2011 May 17. PMID: 21619892

Article Published Date : May 17, 2011

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Oxidative Stress

Pharmacological Actions : Antioxidants, Anxiolytic, Neuroprotective Agents

[+]

Bifidobacterium longum's anxiolytic effect involves vagal pathways for gut-brain communication.Dec 01, 2011

Click here to read the entire abstract

Pubmed Data : Neurogastroenterol Motil. 2011 Dec ;23(12):1132-9. Epub 2011 Oct 11. PMID: 21988661

Article Published Date : Dec 01, 2011

Study Type : Animal Study

Additional Links

Substances : Bifidobacterium Longum

Diseases : Anxiety Disorders, Gut Brain Axis: Imbalance

Pharmacological Actions : Anxiolytic

[+]

Citrus limon has significant behavioral effects in rats, including anxiety reduction.Sep 16, 2014

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Pubmed Data : Metab Brain Dis. 2014 Sep 17. Epub 2014 Sep 17. PMID: 25227172

Article Published Date : Sep 16, 2014

Study Type : Animal Study

Additional Links

Substances : Lemon

Diseases : Anxiety Disorders, Stress and Anxiety

Pharmacological Actions : Anxiolytic

[+]

Curcumin has anti-anxiety properties.Sep 17, 2010

Click here to read the entire abstract

Pubmed Data : Brain Res. 2010 Sep 17;1352:167-75. Epub 2010 Jul 12. PMID: 20633542

Article Published Date : Sep 17, 2010

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Anxiety Disorders

Pharmacological Actions : Anxiolytic

[+]

Damiana exhibits anti-anxiety activity in mice. - Article 1Jan 01, 2005

Click here to read the entire abstract

Pubmed Data : J Herb Pharmacother. 2005;5(4):13-21. PMID: 16635964

Article Published Date : Jan 01, 2005

Study Type : Animal Study

Additional Links

Substances : Damiana

Diseases : Anxiety Disorders

Pharmacological Actions : Anxiolytic

[+]

Echinacea has anti-anxiety properties.Nov 01, 2010

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2010 Nov;24(11):1605-13. PMID: 21031616

Article Published Date : Nov 01, 2010

Study Type : Animal Study

Additional Links

Substances : Echinacea

Diseases : Anxiety Disorders

Pharmacological Actions : Anxiolytic

[+]

Effects of transcranial photobiomodulation and methylene blue on biochemical and behavioral profiles in mice stress model.Mar 31, 2020

Click here to read the entire abstract

Pubmed Data : Lasers Med Sci. 2020 Apr ;35(3):573-584. Epub 2019 Aug 1. PMID: 31372913

Article Published Date : Mar 31, 2020

Study Type : Animal Study

Additional Links

Diseases : Anxiety, Learning disorders, Memory Disorders

Therapeutic Actions : Photobiomodulation

Pharmacological Actions : Antioxidants, Anxiolytic, Neuroprotective Agents, Superoxide Dismutase Up-regulation

[+]

Fish oil supplementation of maternal rats on an n-3 fatty acid-deficient diet prevents depletion of maternal brain regional docosahexaenoic acid levels and has a postpartum anxiolytic effect.May 02, 2011

Click here to read the entire abstract

Pubmed Data : J Nutr Biochem. 2011 May 2. Epub 2011 May 2. PMID: 21543216

Article Published Date : May 02, 2011

Study Type : Animal Study

Additional Links

Substances : DHA (Docosahexaenoic Acid), Fish Oil

Diseases : Postpartum Problems, Prenatal Nutrition

Pharmacological Actions : Anxiolytic

[+]

Horsetail possesses anxiolytic properties.May 01, 2011

Click here to read the entire abstract

Pubmed Data : Indian J Exp Biol. 2011 May ;49(5):352-6. PMID: 21615059

Article Published Date : May 01, 2011

Study Type : Animal Study

Additional Links

Substances : Horsetail

Diseases : Anxiety

Pharmacological Actions : Anxiolytic

Additional Keywords : Phytotherapy, Plant Extracts

[+]

Kava compares favorably with diazepam in reducing anxiety in mice. Jun 01, 2002

Click here to read the entire abstract

Pubmed Data : Prog Neuropsychopharmacol Biol Psychiatry. 2002 Jun;26(5):855-60. PMID: 12369257

Article Published Date : Jun 01, 2002

Study Type : Animal Study

Additional Links

Substances : Kava Kava

Diseases : Anxiety Disorders

Pharmacological Actions : Anxiolytic

Additional Keywords : Benzodiazepine Alternatives, Plant Extracts, Superiority of Natural Substances versus Drugs

[+]

Kava exhibits anxiolytic properties in mice.Oct 01, 2003

Click here to read the entire abstract

Pubmed Data : Psychopharmacology (Berl). 2003 Oct;170(1):33-41. Epub 2003 Jul 4. PMID: 12845414

Article Published Date : Oct 01, 2003

Study Type : Animal Study

Additional Links

Substances : Kava Kava

Diseases : Anxiety Disorders

Pharmacological Actions : Anxiolytic

Additional Keywords : Plant Extracts

[+]

L-theanine works synergistically with the drug midazolam to induce an anxiolytic effect. Aug 01, 2010

Click here to read the entire abstract

Pubmed Data : J Altern Complement Med. 2010 Aug;16(8):875-82. PMID: 20108732

Article Published Date : Aug 01, 2010

Study Type : Animal Study

Additional Links

Substances : Theanine

Diseases : Anxiety Disorders

Pharmacological Actions : Anxiolytic

Additional Keywords : Drug: Midazolam, Drug-Plant-Vitamin Synergies

[+]

Luteolin, a lemon blam flavonoid, may contribute to reducing anxiety through modulating motor movements and locomotion. Feb 01, 2009

Click here to read the entire abstract

Pubmed Data : AANA J. 2009 Feb;77(1):33-6. PMID: 19263826

Article Published Date : Feb 01, 2009

Study Type : Animal Study

Additional Links

Substances : Luteolin, Melissa (Lemonbalm)

Diseases : Anxiety Disorders

Pharmacological Actions : Anxiolytic

[+]

Magnolia officinalis has anxiolytic properties.Apr 18, 2011

Click here to read the entire abstract

Pubmed Data : J Med Food. 2011 Apr 18. Epub 2011 Apr 18. PMID: 21501091

Article Published Date : Apr 18, 2011

Study Type : Animal Study

Additional Links

Substances : Magnolia

Diseases : Anxiety Disorders

Pharmacological Actions : Anxiolytic, Benzodiazepine receptor agonist, GABA Modulators

[+]

Neem compare favorably to diazepam in reducing anxiety in mice without motor side effects. Jun 01, 2010

Click here to read the entire abstract

Pubmed Data : West Indian Med J. 2010 Jun;59(3):245-8. PMID: 21291100

Article Published Date : Jun 01, 2010

Study Type : Animal Study

Additional Links

Substances : Neem

Diseases : Anxiety Disorders

Pharmacological Actions : Anxiolytic

Additional Keywords : Benzodiazepine Alternatives, Drug: Diazepam, Plant Extracts

[+]

Neferine extracted from Lotus seed has sedative anti-anxiety effects.Dec 01, 2008

Click here to read the entire abstract

Pubmed Data : Phytomedicine. 2008 Dec;15(12):1117-24. PMID: 19010651

Article Published Date : Dec 01, 2008

Study Type : Animal Study

Additional Links

Substances : Lotus

Diseases : Anxiety Disorders, Seizures

Pharmacological Actions : Anxiolytic, Hypnotics and Sedatives

Additional Keywords : Plant Extracts

[+]

Progesterone is able to decrease anxiety behavior in younger and older mice. Jun 01, 2006

Click here to read the entire abstract

Pubmed Data : Psychopharmacology (Berl). 2006 Jun;186(3):312-22. Epub 2006 Mar 15. PMID: 16538472

Article Published Date : Jun 01, 2006

Study Type : Animal Study

Additional Links

Substances : Progesterone

Diseases : Aging, Generalized Anxiety Disorder

Pharmacological Actions : Anxiolytic

[+]

Salvinorin A, a compound found within Salvia divinorum, exhibits anxiolytic and antidepressant-like properties. Jul 01, 2009

Click here to read the entire abstract

Pubmed Data : Br J Pharmacol. 2009 Jul;157(5):844-53. Epub 2009 May 5. PMID: 19422370

Article Published Date : Jul 01, 2009

Study Type : Animal Study

Additional Links

Substances : Salvia divinorum

Diseases : Anxiety Disorders, Depression

Pharmacological Actions : Antidepressive Agents, Anxiolytic

[+]

Scopoletin ameliorates anxiety-like behaviors in complete Freund’s adjuvant-induced mouse model.Feb 03, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mol Brain. 2020 Feb 4 ;13(1):15. Epub 2020 Feb 4. PMID: 32019580

Article Published Date : Feb 03, 2020

Study Type : Animal Study

Additional Links

Substances : Scopoletin

Diseases : Anxiety

Pharmacological Actions : Anti-Inflammatory Agents, Anxiolytic

Additional Keywords : Phytotherapy

[+]

Serotonin modulation contributes to the anxiolytic-like effect of inhalation of essential oil from Lavandula officinalis.Jun 30, 2014

Click here to read the entire abstract

Pubmed Data : Nat Prod Commun. 2014 Jul ;9(7):1023-6. PMID: 25230519

Article Published Date : Jun 30, 2014

Study Type : Animal Study

Additional Links

Substances : Lavender

Diseases : Anxiety Disorders, Serotonin Disorders

Pharmacological Actions : Anxiolytic, Serotonergic

[+]

The anxiolytic-like effect of lavender essential oil inhalation in mice is due to the modulation of serotonergic pathways.May 19, 2013

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2013 May 20 ;147(2):412-8. Epub 2013 Mar 22. PMID: 23524167

Article Published Date : May 19, 2013

Study Type : Animal Study

Additional Links

Substances : Lavender

Diseases : Anxiety Disorders

Pharmacological Actions : Anxiolytic, Serotonergic

[+]

The homeopathic remedy Pulsatilla nigricans compares favorably as an anti-anxiety agent to diazepam (Valium). Jun 30, 2012

Click here to read the entire abstract

Pubmed Data : Homeopathy. 2012 Jul ;101(3):171-4. PMID: 22818235

Article Published Date : Jun 30, 2012

Study Type : Animal Study

Additional Links

Substances : Homeopathic Treatment: Pulsatilla nigricans

Diseases : Anxiety Disorders

Therapeutic Actions : Homeopathic Treatment

Pharmacological Actions : Anxiolytic

Additional Keywords : Natural Substances Versus Drugs

[+]

Tilia var. mexicana has anti-anxiety activity without affecting motor activity.Jul 23, 2008

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2008 Jul 23;118(2):312-7. Epub 2008 Apr 24. PMID: 18539420

Article Published Date : Jul 23, 2008

Study Type : Animal Study

Additional Links

Substances : Linden (Tilia)

Diseases : Anxiety Disorders

Pharmacological Actions : Anxiolytic

[+]

Valerian's anti-anxiety action is due to its action on GABA receptors.Jun 17, 2008

Click here to read the entire abstract

Pubmed Data : Neuropharmacology. 2008 Jun 17. PMID: 18602406

Article Published Date : Jun 17, 2008

Study Type : Animal Study

Additional Links

Substances : Valerian

Diseases : Anxiety: Generalized, Anxiety Disorders, Generalized Anxiety Disorder

Pharmacological Actions : Anxiolytic, GABA Modulators

[+]

Valeriana officinalis root extracts have potent anxiolytic effects in rats.Dec 28, 2009

Click here to read the entire abstract

Pubmed Data : Phytomedicine. 2009 Dec 28. Epub 2009 Dec 28. PMID: 20042323

Article Published Date : Dec 28, 2009

Study Type : Animal Study

Additional Links

Substances : Valerian

Diseases : Anxiety Disorders

Pharmacological Actions : Anxiolytic

[+]

Magnolia and Ziziphus extracts modulate central nervous system receptors in a manner consistent with their traditional use as anxiolytic and sleep-inducing. Jul 30, 2009

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2009 Jul 30;124(3):421-5. Epub 2009 Jun 6. PMID: 19505549

Article Published Date : Jul 30, 2009

Study Type : In Vitro Study

Additional Links

Substances : Magnolia, Ziziphus spinosa

Diseases : Anxiety Disorders, Insomnia

Pharmacological Actions : Anxiolytic, Benzodiazepine receptor agonist

Additional Keywords : Benzodiazepine Receptor Agonist

[+]

Noni may reduce anxiety via affinity with GABA receptors.Aug 01, 2007

Click here to read the entire abstract

Pubmed Data : Phytomedicine. 2007 Aug;14(7-8):517-22. Epub 2007 Jun 11. PMID: 17561385

Article Published Date : Aug 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Noni

Diseases : Anxiety Disorders, Generalized Anxiety Disorder

Pharmacological Actions : Anxiolytic, GABA Modulators

[+]

Studies assessed in the present chapter clearly suggest an anxiolytic-like effect of CBD in both animal models and healthy volunteers.May 08, 2016

Click here to read the entire abstract

Pubmed Data : Curr Neuropharmacol. 2016 May 9. Epub 2016 May 9. PMID: 27157263

Article Published Date : May 08, 2016

Study Type : Review

Additional Links

Substances : Cannabidiol

Diseases : Anxiety Disorders

Pharmacological Actions : Anti-Anxiety Agents, Anxiolytic

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View the Evidence: 69 Abstracts with Anxiolytic Research

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Kava Kava appears to be a short-term treatment for anxiety, but not a replacement for prolonged anti-anxiety use. Oct 31, 2018

Lavender and rose oil aromatherapy has been determined to have anti-anxiety activity.Jan 01, 2010

Systematic review: psychedelics appear to be effective in significantly reducing symptoms of depression and anxiety and are well-tolerated.Jul 29, 2019

The current weight of evidence supports the use of kava in treatment of anxiety with a significant result occurring in four out of six studies reviewed.Jan 01, 2011

This meta-analysis showed a significant improvement in sleep quality and generalized anxiety disorder.Jun 01, 2019

432 Hz Music has an anxiolytic effect in the treatment of endodontic treatment.Aug 31, 2016

A combination of Magnolia and Phellodendron reduces symptoms of stress and anxiety in premenopausal women.Sep 01, 2005

Bach flower remedies appear to reduce anxiety in human subjects.Jul 01, 2001

Blue skullcap (S. lateriflora) demonstates anti-anxiety activity in human subjects. Mar 01, 2003

Cannabidiol reduces anxiety in social anxiety disorder through modulating the limbic and paralimbic brain areas. Sep 09, 2010

Chamomile extract has a positive effect in reducing symptoms in patients with generalized anxiety disorder. Aug 01, 2009

Chamomile improves cortisol patterns in subjects with moderate to severe generalized anxiety disorder.Jan 01, 2018

Chamomile may provide clinically meaningful antidepressant activity that occurs in addition to its previously observed anxiolytic activity.Aug 31, 2012

Clinical efficacy of Manasamitra Vataka (an Ayurveda medication) on generalized anxiety disorder with comorbid generalized social phobia: a randomized controlled study.May 31, 2012

Echium amoenum may have therapeutic value in the treatment of obessive-compulsive disorder.Dec 01, 2006

EFT results in reduced psychological stress and cortisol in human subjects.Sep 30, 2012

Emotional freedom techniques improves multiple physiological markers of health.Dec 31, 2018

Emotional Freedom Techniques show promise as feasible treatments for test anxiety.Oct 31, 2009

Gotu kola may have therapeutic efficacy in the treatment of anxiety syndromes.Dec 01, 2000

Hericium erinaceus intake results in a reduction of depression and anxiety in mice by 4 weeks. Aug 01, 2010

Kava is safe and effective in treating anxiety disorders and depression.Aug 01, 2009

Kava was judged to be an effective and safe treatment of non-psychotic anxiety syndrome.Apr 01, 2004

Kava was judged to improve the mood, particularly by reducing anxiety in perimenopausal women.Dec 01, 2008

Lavender essence has a positive effect on anxiety and blood cortisol level among patients about to undergo open heart surgery. Jun 30, 2016

LSD can reduce anxiety.Mar 02, 2014

Melatonin and to a lesser degree mothewort decrease retinal sensitivity and improves the emotional state in anxious young subjects.Nov 01, 2006

Melissa officinalis and Valeriana officinalis have an anti-anxiety effect during laboratory-induced stress. Feb 01, 2006

Motherwort improves symptoms of anxiety and depression in patients with arterial hypertension.Apr 01, 2011

Oral treatment with L-lysine and L-arginine reduces anxiety and basal cortisol levels in healthy humans.Apr 01, 2007

Passionflower as a premedication reduces anxiety without inducing sedation.Jun 01, 2008

Rhodiola rosea significantly improves generalized anxiety disorder (GAD)Mar 01, 2008

Silexan, an orally administered Lavandula oil preparation, is effective in the treatment of 'subsyndromal' anxiety disorder.Aug 31, 2010

Subchronic treatment with amino acid mixture of L-lysine and L-arginine may have ameliorative value during psychosocial stress.Jun 01, 2005

Sweet orange essential oil has anti-anxiety properties.Jul 31, 2012

The inhalation of lavender oil has stress reducing effects. Mar 31, 2012

The practice of asanas and yoga decreased anxiety in women.Jan 16, 2014

Tryptophan-rich gourd seeds are a potential anxiolytic to those suffering from social phobia.Sep 01, 2007

A methanolic extract of Piper nigrum ameliorates beta-amyloid (1–42)-induced anxiety and depression by attenuation of the oxidative stress in the rat amygdala.Dec 31, 2014

Amelioration of age-related cognitive decline and anxiety in mice by Centella asiatica extract varies by sex, dose and mode of administration.Dec 31, 2023

Angelica root coumarins display synergistic anxiolytic activity.Jan 10, 2013

Angelica whole plant and leaf display the highest anxiolytic activity whereas the root, fruit, intermediate, and stem display the least.Jul 01, 2012

Astaxanthin prevents fish-oil induced oxidative stress in the anterior forebrain of animals, resulting in an anxiety reducing effect. May 17, 2011

Bifidobacterium longum's anxiolytic effect involves vagal pathways for gut-brain communication.Dec 01, 2011

Citrus limon has significant behavioral effects in rats, including anxiety reduction.Sep 16, 2014

Curcumin has anti-anxiety properties.Sep 17, 2010

Damiana exhibits anti-anxiety activity in mice. - Article 1Jan 01, 2005

Echinacea has anti-anxiety properties.Nov 01, 2010

Effects of transcranial photobiomodulation and methylene blue on biochemical and behavioral profiles in mice stress model.Mar 31, 2020

Fish oil supplementation of maternal rats on an n-3 fatty acid-deficient diet prevents depletion of maternal brain regional docosahexaenoic acid levels and has a postpartum anxiolytic effect.May 02, 2011

Horsetail possesses anxiolytic properties.May 01, 2011

Kava compares favorably with diazepam in reducing anxiety in mice. Jun 01, 2002

Kava exhibits anxiolytic properties in mice.Oct 01, 2003

L-theanine works synergistically with the drug midazolam to induce an anxiolytic effect. Aug 01, 2010

Luteolin, a lemon blam flavonoid, may contribute to reducing anxiety through modulating motor movements and locomotion. Feb 01, 2009

Magnolia officinalis has anxiolytic properties.Apr 18, 2011

Neem compare favorably to diazepam in reducing anxiety in mice without motor side effects. Jun 01, 2010

Neferine extracted from Lotus seed has sedative anti-anxiety effects.Dec 01, 2008

Progesterone is able to decrease anxiety behavior in younger and older mice. Jun 01, 2006

Salvinorin A, a compound found within Salvia divinorum, exhibits anxiolytic and antidepressant-like properties. Jul 01, 2009

Scopoletin ameliorates anxiety-like behaviors in complete Freund’s adjuvant-induced mouse model.Feb 03, 2020

Serotonin modulation contributes to the anxiolytic-like effect of inhalation of essential oil from Lavandula officinalis.Jun 30, 2014

The anxiolytic-like effect of lavender essential oil inhalation in mice is due to the modulation of serotonergic pathways.May 19, 2013

The homeopathic remedy Pulsatilla nigricans compares favorably as an anti-anxiety agent to diazepam (Valium). Jun 30, 2012

Tilia var. mexicana has anti-anxiety activity without affecting motor activity.Jul 23, 2008

Valerian's anti-anxiety action is due to its action on GABA receptors.Jun 17, 2008

Valeriana officinalis root extracts have potent anxiolytic effects in rats.Dec 28, 2009

Magnolia and Ziziphus extracts modulate central nervous system receptors in a manner consistent with their traditional use as anxiolytic and sleep-inducing. Jul 30, 2009

Noni may reduce anxiety via affinity with GABA receptors.Aug 01, 2007

Studies assessed in the present chapter clearly suggest an anxiolytic-like effect of CBD in both animal models and healthy volunteers.May 08, 2016

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Anxiolytic

View the Evidence:
69 Abstracts with Anxiolytic Research