Remyelination

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3 Problem Substances Researched for Remyelination
NameACCKFocus
Statin Drugs23Locked
Lovastatin11Locked
Mercury11Locked
21 Diseases Researched for Remyelination
NameACCKFocus
Multiple Sclerosis1126Locked
Demyelinating Diseases812Locked
Glaucoma110Locked
Peripheral Nerve Diseases24Locked
Peripheral Neuropathies24Locked
Brain Inflammation 23Locked
Cerebral Ischemia12Locked
Cognitive Decline/Dysfunction12Locked
Drug-Induced Nutrient Depletion: Statin Drugs12Locked
Neonatal Stroke12Locked
Neurologic Disorders22Locked
Parasitic Diseases12Locked
Stroke: Attenuation/Recovery 12Locked
Subarachnoid hemorrhage12Locked
Amyotrophic Lateral Sclerosis11Locked
Mercury Poisoning11Locked
Muscle Atrophy 11Locked
Neurodegenerative Diseases11Locked
Neuropathies11Locked
Spinal Cord Injuries11Locked
Statin-Induced Pathologies11Locked
1 Adverse Pharmacological Actions Researched for Remyelination
NameACCKFocus
Neurotoxic23Locked
21 Substances Researched for Remyelination
NameACCKFocus
Citicoline110Locked
Vitamin D34Locked
Ginkgo biloba13Locked
Berberine12Locked
EPA (Eicosapentaenoic Acid)12Locked
Evening Primrose Oil12Locked
Flavonoids22Locked
Goldenthread12Locked
Hemp Seed12Locked
Melatonin12Locked
Rosmarinic acid12Locked
Tanshinone IIA12Locked
Ursolic Acid12Locked
Arginine11Locked
Ginsenosides11Locked
Phloretin11Locked
Progesterone11Locked
Quercetin11Locked
SAMe (S-adenosylmethionine)11Locked
Wasabi11Locked
acetyl-11-keto-beta-boswellic acid11Locked
3 Therapeutic Actions Researched for Remyelination
NameACCKFocus
Laser Treatment 23Locked
Electroacupuncture12Locked
Photobiomodulation11Locked
14 Pharmacological Actions Researched for Remyelination
NameACCKFocus
Anti-Inflammatory Agents611Locked
Neuroprotective Agents710Locked
Antioxidants35Locked
Heme oxygenase-1 up-regulation24Locked
Interleukin-10 upregulation24Locked
Nrf2 activation24Locked
Remyelination24Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor24Locked
Neuritogenic23Locked
Interleukin-1 beta downregulation12Locked
Interleukin-6 Downregulation12Locked
Neurogenesis12Locked
Neurorestorative12Locked
Anti-Apoptotic11Locked

View the Evidence:
26 Abstracts with Remyelination Research

[+]

Citicoline: A candidate for adjunct treatment of multiple sclerosis. Apr 01, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceuticals (Basel). 2021 Apr 2 ;14(4). Epub 2021 Apr 2. PMID: 33918331
Article Published Date : Apr 01, 2021
Study Type : Human Study
Additional Links
Substances : Citicoline
Diseases : Glaucoma, Multiple Sclerosis
Additional Keywords : Remyelination
[+]

Ginkgolide K supports remyelination via induction of astrocytic IGF/PI3K/Nrf2 axis.Sep 30, 2019

Pubmed Data : Int Immunopharmacol. 2019 Oct ;75:105819. Epub 2019 Aug 14. PMID: 31421546
Article Published Date : Sep 30, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Ginkgo biloba
Diseases : Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation, Remyelination
Additional Keywords : Remyelination
[+]

Berberine promotes neurite extension and axonal regeneration in injured nerves of the peripheral nervous systemApr 01, 2012

Pubmed Data : J Med Food. 2012 Apr ;15(4):413-7. Epub 2012 Feb 8. PMID: 22316297
Article Published Date : Apr 01, 2012
Study Type : Animal Study
Additional Links
Substances : Berberine, Goldenthread
Diseases : Demyelinating Diseases, Peripheral Nerve Diseases, Peripheral Neuropathies
Pharmacological Actions : Neuritogenic
Additional Keywords : Nerve Regeneration, Remyelination, Sciatic Nerve
[+]

Electroacupuncture treatment is a potential therapy for the treatment of cognitive deficit after subarachnoid hemorrhage.Nov 15, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Metab Brain Dis. 2022 Nov 16. Epub 2022 Nov 16. PMID: 36383326
Article Published Date : Nov 15, 2022
Study Type : Animal Study
Additional Links
Diseases : Cognitive Decline/Dysfunction, Subarachnoid hemorrhage
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Remyelination
[+]

EPA stimulates myelination in the rat brain. Mar 01, 2008

Pubmed Data : J Neurosci Res. 2008 Mar;86(4):776-84. PMID: 17941053
Article Published Date : Mar 01, 2008
Study Type : Animal Study
Additional Links
Substances : EPA (Eicosapentaenoic Acid)
Diseases : Demyelinating Diseases
Additional Keywords : Remyelination
[+]

Hemp seed oil and evening primrose oil has beneficial effects on the repair of myelin.Jan 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Res Pharm Sci. 2019 Feb ;14(1):36-45. PMID: 30936931
Article Published Date : Jan 31, 2019
Study Type : Animal Study
Additional Links
Substances : Evening Primrose Oil, Hemp Seed
Diseases : Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
Additional Keywords : Gene Expression Regulation, Remyelination
[+]

Laser treatment induces peripheral nerve regeneration.Jun 01, 2007

Pubmed Data : Photomed Laser Surg. 2007 Jun;25(3):137-43. PMID: 17603852
Article Published Date : Jun 01, 2007
Study Type : Animal Study
Additional Links
Diseases : Peripheral Nerve Diseases, Peripheral Neuropathies
Therapeutic Actions : Laser Treatment
Additional Keywords : Remyelination
[+]

Melatonin promotes myelination by decreasing white matter inflammation after neonatal stroke.Jan 01, 2011

Pubmed Data : Pediatr Res. 2011 Jan;69(1):51-5. PMID: 20856166
Article Published Date : Jan 01, 2011
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Brain Inflammation , Demyelinating Diseases, Neonatal Stroke, Stroke: Attenuation/Recovery
Pharmacological Actions : Neuroprotective Agents, Neurorestorative
Additional Keywords : Remyelination
[+]

Rosmarinic acid ameliorates hypoxia/ischemia induced cognitive deficits and promotes remyelination.Apr 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neural Regen Res. 2020 May ;15(5):894-902. PMID: 31719255
Article Published Date : Apr 30, 2020
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Cerebral Ischemia
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Remyelination
[+]

Statin drugs interfere with neurological healing by inhibiting myelin formation. Dec 10, 2008

Pubmed Data : J Neurosci. 2008 Dec 10 ;28(50):13609-14. PMID: 19074034
Article Published Date : Dec 10, 2008
Study Type : Animal Study
Additional Links
Diseases : Demyelinating Diseases, Drug-Induced Nutrient Depletion: Statin Drugs, Multiple Sclerosis
Additional Keywords : Remyelination
Problem Substances : Statin Drugs
Adverse Pharmacological Actions : Neurotoxic
[+]

Tanshinone IIA attenuates demyelination and promotes remyelination in A. cantonensis-infected BALB/c mice.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Biol Sci. 2019 ;15(10):2211-2223. Epub 2019 Aug 19. PMID: 31592236
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Tanshinone IIA
Diseases : Parasitic Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Remyelination
[+]

Ursolic acid enhances myelin repair in adult mice brains.Aug 16, 2022

Pubmed Data : J Mol Neurosci. 2022 Aug 17. Epub 2022 Aug 17. PMID: 35976486
Article Published Date : Aug 16, 2022
Study Type : Animal Study
Additional Links
Substances : Ursolic Acid
Diseases : Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Remyelination
[+]

Vitamin D increases remyelination by promoting oligodendrocyte lineage differentiation.Dec 12, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Brain Behav. 2019 Dec 13:e01498. Epub 2019 Dec 13. PMID: 31837111
Article Published Date : Dec 12, 2019
Study Type : Animal Study
Additional Links
Substances : Vitamin D
Diseases : Multiple Sclerosis
Pharmacological Actions : Neurogenesis
Additional Keywords : Remyelination
[+]

Acetyl-11-keto-beta boswellic acid mediated neuroprotection in methyl mercury-induced experimental model of ALS.May 31, 2021

Pubmed Data : Neurochem Res. 2021 Jun 1. Epub 2021 Jun 1. PMID: 34075522
Article Published Date : May 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : acetyl-11-keto-beta-boswellic acid
Diseases : Amyotrophic Lateral Sclerosis, Mercury Poisoning
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Neuroprotective Agents, Nrf2 activation
Additional Keywords : Methylmercury, Remyelination
Problem Substances : Mercury
[+]

Arginine and S-adenosylmethionine may contribute to nerve regeneration. Jun 01, 2008

Pubmed Data : J Appl Physiol. 2008 Jun;104(6):1727-35. Epub 2008 Mar 6. PMID: 7941963
Article Published Date : Jun 01, 2008
Study Type : Review
Additional Links
Substances : Arginine, SAMe (S-adenosylmethionine)
Diseases : Demyelinating Diseases
Additional Keywords : Myelination, Remyelination
[+]

Ginsenoside Rg1 could maintain the integrity of myelin and is a promising candidate for functional recovery in demyelinating diseases.Oct 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Phytomedicine. 2022 Nov ;106:154309. Epub 2022 Jul 1. PMID: 35994846
Article Published Date : Oct 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Multiple Sclerosis
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Remyelination
[+]

Lovastatin may adversely affect myelin formation and the remyelination process. Apr 01, 1994

Pubmed Data : J Neurochem. 1994 Apr ;62(4):1539-45. PMID: 8133281
Article Published Date : Apr 01, 1994
Study Type : In Vitro Study
Additional Links
Diseases : Demyelinating Diseases, Statin-Induced Pathologies
Additional Keywords : Remyelination
Problem Substances : Lovastatin, Statin Drugs
Adverse Pharmacological Actions : Neurotoxic
[+]

Phloretin enhances remyelination by stimulating oligodendrocyte precursor cell differentiation.Nov 15, 2022

Pubmed Data : Proc Natl Acad Sci U S A. 2022 Nov 16 ;119(46):e2120393119. Epub 2022 Nov 7. PMID: 36343243
Article Published Date : Nov 15, 2022
Study Type : In Vitro Study
Additional Links
Substances : Phloretin
Diseases : Multiple Sclerosis
Pharmacological Actions : Remyelination
Additional Keywords : Remyelination
[+]

Phototherapy with laser may contribute to muscle preservation and nerve regeneration.Jan 01, 2009

Pubmed Data : Int Rev Neurobiol. 2009;87:445-64. PMID: 19682654
Article Published Date : Jan 01, 2009
Study Type : Review
Additional Links
Diseases : Demyelinating Diseases, Muscle Atrophy , Neurologic Disorders, Neuropathies
Therapeutic Actions : Laser Treatment , Photobiomodulation
Additional Keywords : Remyelination
[+]

Pinocembrin promotes OPC differentiation and remyelination via the mTOR signaling pathway.Aug 31, 2021

Pubmed Data : Neurosci Bull. 2021 Sep ;37(9):1314-1324. Epub 2021 Jun 6. PMID: 34091810
Article Published Date : Aug 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Multiple Sclerosis
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Remyelination
[+]

Progesterone may offer a therapeutic option for neuroprotection and myelin repair. Oct 01, 2007

Pubmed Data : Pharmacol Ther. 2007 Oct;116(1):77-106. Epub 2007 Jun 18. PMID: 17659348
Article Published Date : Oct 01, 2007
Study Type : Review
Additional Links
Substances : Progesterone
Diseases : Demyelinating Diseases
Additional Keywords : Myelination, Remyelination
[+]

Quercetin as a possible complementary therapy in multiple sclerosis.Oct 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Heliyon. 2023 Nov ;9(11):e21741. Epub 2023 Oct 29. PMID: 37954351
Article Published Date : Oct 31, 2023
Study Type : Review
Additional Links
Substances : Quercetin
Diseases : Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Additional Keywords : Remyelination
[+]

The flavonoid agathisflavone modulates the microglial neuroinflammatory response and enhances remyelination.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacol Res. 2020 09 ;159:104997. Epub 2020 Jun 11. PMID: 32534098
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Brain Inflammation , Neurodegenerative Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
Additional Keywords : Remyelination
[+]

Vitamin D promotes remyelination by suppressing c-Myc and inducing oligodendrocyte precursor cell differentiation.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Biol Sci. 2022 ;18(14):5391-5404. Epub 2022 Aug 29. PMID: 36147469
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Vitamin D
Diseases : Spinal Cord Injuries
Pharmacological Actions : Anti-Apoptotic
Additional Keywords : Remyelination
[+]

Vitamin D seems to play a role in the central nervous system and this hypothesis is that VD is involved in remyelination.Jun 15, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neurologia. 2016 Jun 16. Epub 2016 Jun 16. PMID: 27321170
Article Published Date : Jun 15, 2016
Study Type : Review
Additional Links
Substances : Vitamin D
Diseases : Multiple Sclerosis
Additional Keywords : Remyelination
[+]

Wasabi has significant neuritogenic-promoting activity, indicating its possible therapeutic role in neurological disorders.Oct 24, 2008

Pubmed Data : J Neurochem. 2008 Oct 24. PMID: 18796006
Article Published Date : Oct 24, 2008
Study Type : In Vitro Study
Additional Links
Substances : Wasabi
Diseases : Neurologic Disorders
Pharmacological Actions : Neuritogenic
Additional Keywords : Remyelination

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