Focused Research Topics Statin Drugs & Memory Disorders

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Associated Topics included in this Focused Research

Atorvastatin Cerivastatin Fluvastatin Lovastatin Pravastatin Rosuvastatin Simvastatin Statin Drugs

This document was generated from a Focused Research webpage from GreenMedInfo.com

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6 Research Articles in Total

Short-term memory loss associated with rosuvastatin has been reported.

Pubmed Data : Pharmacotherapy. 2006 Aug ;26(8):1190-2. PMID: 16863497
Article Published Date : Aug 01, 2006
Authors : Laura Galatti, Giovanni Polimeni, Francesco Salvo, Marcello Romani, Aurelio Sessa, Edoardo Spina
Study Type : Human: Case Report
Additional Links
Diseases : Memory Disorders : CK(344) : AC(104), Statin-Induced Pathologies : CK(1638) : AC(327)
Problem Substances : Rosuvastatin : CK(71) : AC(17), Statin Drugs : CK(4171) : AC(500)
Adverse Pharmacological Actions : Neurotoxic : CK(1251) : AC(224)

Simvastatin-induced decline in cognition has been reported.

Pubmed Data : Ann Pharmacother. 2006 Oct ;40(10):1880-3. Epub 2006 Aug 29. PMID: 16940411
Article Published Date : Oct 01, 2006
Authors : Kalpana P Padala, Prasad R Padala, Jane F Potter
Study Type : Human: Case Report
Additional Links
Diseases : Cognitive Decline/Dysfunction : CK(1163) : AC(215), Memory Disorders : CK(344) : AC(104), Memory Loss : CK(153) : AC(40), Statin-Induced Pathologies : CK(1638) : AC(327)
Problem Substances : Simvastatin : CK(754) : AC(153)
Adverse Pharmacological Actions : Neurotoxic : CK(1251) : AC(224)

Cognitive impairment associated with statin drug use has been reported.

Pubmed Data : Pharmacotherapy. 2003 Dec ;23(12):1663-7. PMID: 14695047
Article Published Date : Dec 01, 2003
Authors : Deborah S King, Amanda J Wilburn, Marion R Wofford, T Kristopher Harrell, Brent J Lindley, Daniel W Jones
Study Type : Review
Additional Links
Diseases : Cognitive Decline/Dysfunction : CK(1163) : AC(215), Dementia : CK(571) : AC(79), Memory Disorders : CK(344) : AC(104)
Problem Substances : Atorvastatin : CK(516) : AC(99), Cholesterol Lowering Drugs : CK(2451) : AC(391), Simvastatin : CK(754) : AC(153), Statin Drugs : CK(4171) : AC(500)
Adverse Pharmacological Actions : Neurotoxic : CK(1251) : AC(224)

Statin drugs show no cognitive or anti-amyloid benefits and may be associated with cognitive impairment.

Pubmed Data : Pharmacotherapy. 2003 Jul ;23(7):871-80. PMID: 12885101
Article Published Date : Jul 01, 2003
Authors : Leslie R Wagstaff, Melinda W Mitton, Beth McLendon Arvik, P Murali Doraiswamy
Study Type : Human Study
Additional Links
Diseases : Cognitive Decline/Dysfunction : CK(1163) : AC(215), Memory Disorders : CK(344) : AC(104)
Problem Substances : Lovastatin : CK(267) : AC(68), Pravastatin : CK(251) : AC(42), Simvastatin : CK(754) : AC(153), Statin Drugs : CK(4171) : AC(500)
Adverse Pharmacological Actions : Neurotoxic : CK(1251) : AC(224)

Statin-associated adverse cognitive effects have been reported with 90% resolving after drug discontinuation.

Pubmed Data : Pharmacotherapy. 2009 Jul ;29(7):800-11. PMID: 19558254
Article Published Date : Jul 01, 2009
Authors : Marcella A Evans, Beatrice A Golomb
Study Type : Human Study
Additional Links
Diseases : Alzheimer's Disease : CK(1292) : AC(382), Cognitive Decline/Dysfunction : CK(1163) : AC(215), Dementia : CK(571) : AC(79), Memory Disorders : CK(344) : AC(104), Memory Loss : CK(153) : AC(40)
Problem Substances : Statin Drugs : CK(4171) : AC(500)
Adverse Pharmacological Actions : Neurotoxic : CK(1251) : AC(224)

Statin-induced memory loss has been reported.

Pubmed Data : Pharmacotherapy. 2001 Jun ;21(6):767-9. PMID: 11401190
Article Published Date : Jun 01, 2001
Authors : A Orsi, O Sherman, Z Woldeselassie
Study Type : Human: Case Report
Additional Links
Diseases : Memory Disorders : CK(344) : AC(104)
Pharmacological Actions : Anticholesteremic Agents : CK(1244) : AC(230)
Problem Substances : Statin Drugs : CK(4171) : AC(500)
Adverse Pharmacological Actions : Neurotoxic : CK(1251) : AC(224)

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