Phthalate Toxicity

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37 Substances Researched for Phthalate Toxicity
NameACCKFocus
Lycopene1018Locked
Curcumin611Locked
beta-Carotene110Locked
Alpha-Lipoic Acid27Locked
Flavonoids47Locked
Celery Oil36Locked
Goji36Locked
Vitamin C36Locked
NAC (N-acetyl-L-cysteine)24Locked
Naringenin 24Locked
Vitamin E24Locked
Zinc24Locked
Ellagic Acid23Locked
Green Tea23Locked
Polyphenols23Locked
Quercetin23Locked
Resveratrol23Locked
Antioxidant formulas12Locked
Carvacrol12Locked
Celery seed12Locked
Citrus naringin12Locked
Garcinia kola12Locked
Garlic12Locked
Genistein12Locked
Lactobacillus salivarius 12Locked
Nicotinamide12Locked
Probiotics12Locked
Rutin12Locked
Tetrahydrocurcumin12Locked
Thymol12Locked
Vanillic Acid12Locked
Black Tea11Locked
Carotenoids11Locked
Lactobacillus plantarum11Locked
Lactobacillus rhamnosus GG11Locked
Lion's Mane (Hericium Erinaceus)11Locked
Myricetin11Locked
17 Problem Substances Researched for Phthalate Toxicity
NameACCKFocus
Phthalates2321195Locked
Bisphenol A 30155Locked
Polystyrene nanoparticles815Locked
Endocrine Disrupting Chemicals (EDCs)211Locked
Bisphenol F110Locked
Margarine110Locked
Organophosphates110Locked
Parabens110Locked
Perfluorinated compounds110Locked
Polycyclic aromatic hydrocarbon110Locked
Triclosan110Locked
Nano Plastic-and Micro-Particles35Locked
Bisphenol S12Locked
Aflatoxin11Locked
Heavy Metals11Locked
Infant Formula11Locked
Perfume: Synthetic11Locked
1 Therapeutic Actions Researched for Phthalate Toxicity
NameACCKFocus
Sweating110Locked
1 Problematic Actions Researched for Phthalate Toxicity
NameACCKFocus
Face Masks: Cloth15Locked

View the Evidence:
239 Abstracts with Phthalate Toxicity Research

[+]

Association of phthalate exposure with precocious and delayed pubertal timing in girls and boys.Feb 23, 2020

Pubmed Data : Environ Sci Process Impacts. 2020 Feb 24. Epub 2020 Feb 24. PMID: 32091510
Article Published Date : Feb 23, 2020
Study Type : Meta Analysis, Review
Additional Links
Diseases : Phthalate Toxicity , Puberty: Delayed, Puberty: Precocious
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

Phthalate exposure and the metabolic syndrome.Sep 14, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Pollut. 2023 Sep 15 ;333:121957. Epub 2023 Jun 14. PMID: 37328121
Article Published Date : Sep 14, 2023
Study Type : Meta Analysis
Additional Links
Diseases : Metabolic Diseases, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Phthalate exposure as a hidden risk factor for uterine leiomyoma in adult women.Sep 17, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2024 Sep 18 ;285:117069. Epub 2024 Sep 18. PMID: 39299212
Article Published Date : Sep 17, 2024
Study Type : Meta Analysis
Additional Links
Diseases : Leiomyoma, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Prenatal phthalate exposure and altered patterns of DNA methylation in cord blood.Jun 30, 2017

Pubmed Data : Environ Mol Mutagen. 2017 Jul ;58(6):398-410. Epub 2017 May 28. PMID: 28556291
Article Published Date : Jun 30, 2017
Study Type : Meta Analysis
Additional Links
Diseases : Phthalate Toxicity , Prenatal Chemical Exposures
Additional Keywords : DNA Methylation, Hypomethylation
[+]

This study suggested a positive association between DEHP and BBzP exposure and childhood asthma.Jul 06, 2017

Pubmed Data : Environ Pollut. 2017 Jul 7 ;229:655-660. Epub 2017 Jul 7. PMID: 28692937
Article Published Date : Jul 06, 2017
Study Type : Meta Analysis, Review
Additional Links
Diseases : Asthma: Childhood, Phthalate Toxicity
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

Exposure to phthalates is associated with the occurrence of endometriosis and affects women's reproductive prognosis and ovarian function.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Cell Dev Biol. 2023 ;11:1154923. Epub 2023 Jul 25. PMID: 37560165
Article Published Date : Dec 31, 2022
Study Type : Animal Study, Human Study
Additional Links
Diseases : Endometriosis, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Urine phthalate levels were associated with skin barrier dysfunction and atopic sensitization in children Mar 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur Rev Med Pharmacol Sci. 2023 Apr ;27(7):2888-2898. PMID: 37070889
Article Published Date : Mar 31, 2023
Study Type : Human Study
Additional Links
Diseases : Atopic Dermatitis, Phthalate Toxicity
Problem Substances : Phthalates
[+]

A study of the relationship between phthalate exposure and the occurrence of adult asthma.Jul 04, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2023 Jul 5 ;28(13). Epub 2023 Jul 5. PMID: 37446892
Article Published Date : Jul 04, 2023
Study Type : Human Study
Additional Links
Diseases : Asthma, Phthalate Toxicity
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

Adolescent urinary concentrations of phthalate metabolites and indices of overweight and cardiovascular risk in Dutch adolescents.Nov 30, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Int. 2024 Dec ;194:109167. Epub 2024 Nov 26. PMID: 39616961
Article Published Date : Nov 30, 2024
Study Type : Human Study
Additional Links
Diseases : Cardiovascular Diseases, Obesity, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Association between phthalate exposure and blood pressure during pregnancy.Nov 19, 2019

Pubmed Data : Ecotoxicol Environ Saf. 2019 Nov 20:109944. Epub 2019 Nov 20. PMID: 31757513
Article Published Date : Nov 19, 2019
Study Type : Human Study
Additional Links
Diseases : Hypertension, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Association between phthalates and sleep problems in the U.S. adult females.Mar 26, 2023

Pubmed Data : Int J Environ Health Res. 2023 Mar 27:1-16. Epub 2023 Mar 27. PMID: 36973994
Article Published Date : Mar 26, 2023
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity , Sleep Disorders
Problem Substances : Phthalates
[+]

Association between phthalates exposure and myocardial damage in the general population.Nov 14, 2024

Pubmed Data : Environ Res. 2024 Nov 15 ;261:119632. Epub 2024 Jul 25. PMID: 39025350
Article Published Date : Nov 14, 2024
Study Type : Human Study
Additional Links
Diseases : Cardiovascular Diseases, Phthalate Toxicity
Problem Substances : Phthalates
Adverse Pharmacological Actions : Cardiotoxic
[+]

Association between urinary phthalate metabolites and chronic obstructive pulmonary disease.Dec 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Chron Obstruct Pulmon Dis. 2024 ;19:1421-1431. Epub 2024 Jun 24. PMID: 38948906
Article Published Date : Dec 31, 2023
Study Type : Human Study
Additional Links
Diseases : Chronic Obstructive Pulmonary Disease, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Association of phthalate exposure with pulmonary function in adults.Aug 22, 2023

Pubmed Data : Environ Res. 2023 Aug 23 ;237(Pt 2):116902. Epub 2023 Aug 23. PMID: 37625539
Article Published Date : Aug 22, 2023
Study Type : Human Study
Additional Links
Diseases : Lung Damage, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Association of urinary phthalate metabolites with all-cause and cardiovascular disease mortality among adults with diabetes mellitus.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Public Health. 2023 ;11:1178057. Epub 2023 May 30. PMID: 37325320
Article Published Date : Dec 31, 2022
Study Type : Human Study
Additional Links
Diseases : All-Cause Mortality, Cardiac Mortality , Cardiovascular Diseases, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Associations between exposure to phthalates and subclinical hypothyroidism in pregnant women during early pregnancy.Jan 11, 2023

Pubmed Data : Environ Pollut. 2023 Jan 12:121051. Epub 2023 Jan 12. PMID: 36642176
Article Published Date : Jan 11, 2023
Study Type : Human Study
Additional Links
Diseases : Hypothyroidism, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Associations between phthalate metabolites and body composition in children aged 8-19 years.Dec 22, 2024

Pubmed Data : Int J Environ Health Res. 2024 Dec 23:1-13. Epub 2024 Dec 23. PMID: 39715723
Article Published Date : Dec 22, 2024
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
[+]

Associations of bisphenol and phthalate exposure and anti-Müllerian hormone levels in women of reproductive age.Jul 31, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : EClinicalMedicine. 2024 Aug ;74:102734. Epub 2024 Jul 17. PMID: 39114272
Article Published Date : Jul 31, 2024
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Phthalate Toxicity
Problem Substances : Bisphenol A
[+]

Associations of phthalates with prostate cancer among the US population.Jan 12, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Reprod Toxicol. 2023 Jan 13:108337. Epub 2023 Jan 13. PMID: 36646329
Article Published Date : Jan 12, 2023
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity , Prostate Cancer
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Associations of prenatal exposure to phthalates and their mixture with lung function in Mexican children.Aug 14, 2024

Pubmed Data : J Hazard Mater. 2024 Aug 15 ;475:134863. Epub 2024 Jun 14. PMID: 38885590
Article Published Date : Aug 14, 2024
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity , Prenatal Chemical Exposures
Problem Substances : Phthalates
[+]

Associations of prenatal exposure to phthalates with measures of cognition in 7.5-month-old infants.Mar 07, 2021

Pubmed Data : Neurotoxicology. 2021 Mar 8 ;84:84-95. Epub 2021 Mar 8. PMID: 33705789
Article Published Date : Mar 07, 2021
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity , Prenatal Chemical Exposures
Problem Substances : Phthalates
[+]

Butyl-benzyl-phthalate has a critical impact on the etiology of major depressive disorder disorder in Mexican patients.Feb 01, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2022 Feb 2 ;19(3). Epub 2022 Feb 2. PMID: 35162759
Article Published Date : Feb 01, 2022
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Phthalate Toxicity
Problem Substances : Bisphenol A , Phthalates
[+]

Child exposure to phthalates may contribute to ADHD, ODD and externalizing and internalizing behaviour problems.Sep 30, 2017

Pubmed Data : Environ Pollut. 2017 Oct ;229:375-385. Epub 2017 Jun 12. PMID: 28614761
Article Published Date : Sep 30, 2017
Study Type : Human Study
Additional Links
Diseases : Attention Deficit Disorder with Hyperactivity, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Combined phthalates influence on glucose and lipid metabolism may increase the possibility for NAFLD and insulin resistance development.Dec 05, 2019

Pubmed Data : Environ Sci Pollut Res Int. 2019 Dec 6. Epub 2019 Dec 6. PMID: 31808097
Article Published Date : Dec 05, 2019
Study Type : Human Study
Additional Links
Diseases : Insulin Resistance, Nonalcoholic fatty liver disease (NAFLD), Phthalate Toxicity
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

Consumer practices represent the substantial source of phthalate exposure in Slovak children.Feb 28, 2017

Pubmed Data : Rev Environ Health. 2017 Mar 1 ;32(1-2):211-214. PMID: 28231065
Article Published Date : Feb 28, 2017
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Margarine, Phthalates
[+]

Cumulative risk assessment of phthalates associated with birth outcomes in pregnant Chinese women.Feb 28, 2017

Pubmed Data : Environ Pollut. 2017 Mar ;222:549-556. Epub 2016 Dec 23. PMID: 28024814
Article Published Date : Feb 28, 2017
Study Type : Human Study
Additional Links
Diseases : Infants: Low Birth Weight, Phthalate Toxicity
Problem Substances : Phthalates
[+]

DEHP and DBP could be risk factors for asthma.Mar 31, 2017

Pubmed Data : Int J Hyg Environ Health. 2017 Apr ;220(2 Pt B):468-477. Epub 2017 Jan 30. PMID: 28174042
Article Published Date : Mar 31, 2017
Study Type : Human Study
Additional Links
Diseases : Asthma, Oxidative Stress, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Di-2-ethylhexyl phthalate (DEHP) exposure increase female infertility.Sep 18, 2024

Pubmed Data : Reprod Toxicol. 2024 Sep 19 ;130:108719. Epub 2024 Sep 19. PMID: 39306260
Article Published Date : Sep 18, 2024
Study Type : Human Study
Additional Links
Diseases : Infertility: Female, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Early life exposure to phthalates and the development of childhood asthma among Canadian children.Mar 06, 2021

Pubmed Data : Environ Res. 2021 Mar 7 ;197:110981. Epub 2021 Mar 7. PMID: 33691158
Article Published Date : Mar 06, 2021
Study Type : Human Study
Additional Links
Diseases : Asthma, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Early-life DEHP exposure alter gut microbiota of newborns and may change their immune responses in later life.Jul 25, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Chem Toxicol. 2019 Jul 26:110700. Epub 2019 Jul 26. PMID: 31356917
Article Published Date : Jul 25, 2019
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity
Additional Keywords : Microbiota
Problem Substances : Phthalates
Adverse Pharmacological Actions : Immunoreactive
[+]

Early-life phthalate exposure was found to be associated with the behavioural characteristics of children.Jan 09, 2020

Pubmed Data : Sci Total Environ. 2020 Jan 10 ;699:134053. Epub 2019 Aug 29. PMID: 31678884
Article Published Date : Jan 09, 2020
Study Type : Human Study
Additional Links
Diseases : Attention Deficit Hyperactivity Disorder, Phthalate Toxicity
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

Endocrine disruptors and bladder function: the role of phthalates in overactive bladder.Dec 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Public Health. 2024 ;12:1493794. Epub 2024 Dec 11. PMID: 39722714
Article Published Date : Dec 31, 2023
Study Type : Human Study
Additional Links
Diseases : Overactive Bladder, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Exposure to Bisphenol A and phthalates metabolites in the third trimester of pregnancy and BMI trajectories.Apr 25, 2018

Pubmed Data : Pediatr Obes. 2018 Apr 26. Epub 2018 Apr 26. PMID: 29700996
Article Published Date : Apr 25, 2018
Study Type : Human Study
Additional Links
Diseases : and obesity, Phthalate Toxicity
Problem Substances : Bisphenol A , Phthalates
[+]

Exposure to bisphenols and phthalates is associated with oxidant stress, insulin resistance, and endothelial dysfunction in children.May 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pediatr Res. 2017 Jun ;81(6):857-864. Epub 2017 Jan 18. PMID: 28099427
Article Published Date : May 31, 2017
Study Type : Human Study
Additional Links
Diseases : Endothelial Dysfunction, Insulin Resistance, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Exposure to certain phthalates may cause the placenta to become thicker and more circular.Oct 09, 2017

Pubmed Data : Environ Res. 2017 Oct 10 ;160:239-246. Epub 2017 Oct 10. PMID: 29028488
Article Published Date : Oct 09, 2017
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity , Placental Insufficiency, Prenatal Chemical Exposures
Problem Substances : Phthalates
[+]

Exposure to environmental phthalates have the potential to alter circulating levels of thyroid hormones in pregnant women.Oct 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health Perspect. 2016 Nov ;124(11):1808-1815. Epub 2016 Aug 6. PMID: 27152641
Article Published Date : Oct 31, 2016
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Exposure to phthalates and bisphenol A is associated with higher risk of cardiometabolic impairment in normal weight children.May 03, 2019

Pubmed Data : Environ Sci Pollut Res Int. 2019 May 4. Epub 2019 May 4. PMID: 31055746
Article Published Date : May 03, 2019
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Obesity, Phthalate Toxicity
Problem Substances : Bisphenol A , Phthalates
[+]

Exposure to phthalates is associated with an increased prevalence of rheumatoid arthritis among adults.Sep 30, 2023

Pubmed Data : Chemosphere. 2023 Oct ;338:139472. Epub 2023 Jul 16. PMID: 37459933
Article Published Date : Sep 30, 2023
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity , Rheumatoid Arthritis
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

Exposure to phthalates may possibly impair control of blood glucose and thereby predispose to pre-diabetes.Jan 14, 2018

Pubmed Data : Sci Total Environ. 2018 Jan 15 ;612:1287-1292. Epub 2017 Sep 8. PMID: 28898934
Article Published Date : Jan 14, 2018
Study Type : Human Study
Additional Links
Diseases : Insulin Resistance, Phthalate Toxicity , Prediabetes
Problem Substances : Phthalates
[+]

Exposure to select phthalates was associated with respiratory morbidity among COPD patients.May 14, 2023

Pubmed Data : Environ Res. 2023 May 15 ;225:115622. Epub 2023 Mar 7. PMID: 36894111
Article Published Date : May 14, 2023
Study Type : Human Study
Additional Links
Diseases : Chronic Obstructive Pulmonary Disease, Phthalate Toxicity
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

Exposure to some phthalates at 5-7 years of age might interfere with thyroid hormones and growth.Nov 20, 2016

Pubmed Data : Sci Total Environ. 2016 Nov 21. Epub 2016 Nov 21. PMID: 27884522
Article Published Date : Nov 20, 2016
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
[+]

Fetal exposure to bisphenols and phthalates and childhood bone mass.Jun 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Res. 2020 Jul ;186:109602. Epub 2020 May 1. PMID: 32668547
Article Published Date : Jun 30, 2020
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Bone Diseases, Fetal Origin of Adult Disease, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A , Phthalates
[+]

Findings suggest that higher phthalate exposure may be related to lower sleep efficiency, shorter sleep duration, and prolonged sleep latency during pregnancy.Sep 30, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Epidemiol. 2024 Oct ;8(5):e329. Epub 2024 Aug 20. PMID: 39170820
Article Published Date : Sep 30, 2024
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity , Sleep Disorders
Problem Substances : Phthalates
[+]

High levels of prenatal exposure to phthalates are significantly associated with decreased skeletal muscle index among girls.Dec 11, 2019

Pubmed Data : Environ Res. 2019 Dec 12 ;182:109020. Epub 2019 Dec 12. PMID: 31863942
Article Published Date : Dec 11, 2019
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity , Prenatal Chemical Exposures
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

High-level dibutyl phthalate exposure was associated with an approximately two-fold increase in the rate of estrogen receptor-positive breast cancer.Apr 16, 2019

Pubmed Data : J Clin Oncol. 2019 Apr 17:JCO1802202. Epub 2019 Apr 17. PMID: 30995175
Article Published Date : Apr 16, 2019
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Phthalate Toxicity
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

High-temperature soup foods in plastic packaging are associated with phthalate body burden and expression of inflammatory mRNAs.Jun 20, 2022

Pubmed Data : Environ Sci Technol. 2022 Jun 21 ;56(12):8416-8427. Epub 2022 May 18. PMID: 35584204
Article Published Date : Jun 20, 2022
Study Type : Human Study
Additional Links
Diseases : Inflammation, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Individual and joint effects of phthalates exposure on the risk of early miscarriage.Mar 22, 2023

Pubmed Data : J Expo Sci Environ Epidemiol. 2023 Mar 23. Epub 2023 Mar 23. PMID: 36959356
Article Published Date : Mar 22, 2023
Study Type : Human Study
Additional Links
Diseases : Miscarriage, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Induced perspiration may be useful to facilitate elimination of some potentially toxic phthalate compounds including DEHP and MEHP.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : ScientificWorldJournal. 2012 ;2012:615068. Epub 2012 Oct 31. PMID: 23213291
Article Published Date : Dec 31, 2011
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity
Therapeutic Actions : Sweating
Pharmacological Actions : Detoxifier
Problem Substances : Phthalates
[+]

Inflammation mediates the adverse effects of urinary phthalate exposure on metabolic disease risk.Dec 25, 2024

Pubmed Data : Ecotoxicol Environ Saf. 2024 Dec 26 ;290:117577. Epub 2024 Dec 26. PMID: 39729938
Article Published Date : Dec 25, 2024
Study Type : Human Study
Additional Links
Diseases : Inflammation, Metabolic Diseases, Obesity, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Internal body concentrations of endocrine disrupting chemicals are associated with an increased risk of subfertility together with alterations in hormone levels.Aug 16, 2015

Pubmed Data : Environ Int. 2015 Aug 17 ;84:154-160. Epub 2015 Aug 17. PMID: 26292060
Article Published Date : Aug 16, 2015
Study Type : Human Study
Additional Links
Diseases : Bisphenol-A Toxicity, Infertility: Male, Phthalate Toxicity
Problem Substances : Bisphenol A , Endocrine Disrupting Chemicals (EDCs), Perfluorinated compounds, Phthalates, Triclosan
Adverse Pharmacological Actions : Anti-Fertility
[+]

Maternal bisphenol and phthalate urine concentrations and weight gain during pregnancy.Dec 17, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Int. 2019 Dec 18 ;135:105342. Epub 2019 Dec 18. PMID: 31864031
Article Published Date : Dec 17, 2019
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Phthalate Toxicity , Pregnancy Complications, Weight Problems
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A , Phthalates
[+]

Maternal Di-(2-ethylhexyl)-Phthalate exposure during pregnancy altered energy metabolism in immature offspring and caused hyperglycemia.Jun 30, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2024 Jul 1 ;279:116494. Epub 2024 May 30. PMID: 38820878
Article Published Date : Jun 30, 2024
Study Type : Human Study
Additional Links
Diseases : Hyperglycemia, Phthalate Toxicity , Prenatal Chemical Exposures
Problem Substances : Phthalates
[+]

Maternal phthalate and bisphenol urine concentrations during pregnancy and early markers of arterial health in children.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health Perspect. 2022 04 ;130(4):47007. Epub 2022 Apr 26. PMID: 35471947
Article Published Date : Dec 31, 2021
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Phthalate Toxicity , Prenatal Chemical Exposures
Problem Substances : Bisphenol A , Phthalates
[+]

Maternal phthalate exposure and BMI trajectory in children.Jun 30, 2024

Pubmed Data : J Expo Sci Environ Epidemiol. 2024 Jul ;34(4):601-609. Epub 2024 Jun 19. PMID: 38898267
Article Published Date : Jun 30, 2024
Study Type : Human Study
Additional Links
Diseases : Obesity, Phthalate Toxicity
Problem Substances : Phthalates
Adverse Pharmacological Actions : Obesogenic
[+]

MEHP exposure was concurrently associated with lower testosterone levels in young, male adults.Mar 26, 2017

Pubmed Data : Environ Pollut. 2017 Mar 27 ;225:112-117. Epub 2017 Mar 27. PMID: 28359975
Article Published Date : Mar 26, 2017
Study Type : Human Study
Additional Links
Diseases : Insulin Resistance, Low Testosterone, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Micromolar sums of the oxidative metabolites of DEHP were all significantly related to diabetes mellitus in males.Jun 04, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2017 Jun 5 ;14(6). Epub 2017 Jun 5. PMID: 28587233
Article Published Date : Jun 04, 2017
Study Type : Human Study
Additional Links
Diseases : Diabetes Mellitus: Type 2, Hyperlipidemia, Phthalate Toxicity
[+]

Mixed exposure to phenyl hydroxides, PAHs, and PAEs increased the risk of arthritis.Sep 08, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Public Health. 2024 Sep 9 ;24(1):2446. Epub 2024 Sep 9. PMID: 39251954
Article Published Date : Sep 08, 2024
Study Type : Human Study
Additional Links
Diseases : Arthritis, Phthalate Toxicity
Problem Substances : Phthalates, Polycyclic aromatic hydrocarbon
[+]

Mono-(2-ethylhexyl) phthalate promotes dengue virus infection by decreasing IL-23-mediated antiviral responses.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2021 ;12:599345. Epub 2021 Feb 15. PMID: 33659001
Article Published Date : Dec 31, 2020
Study Type : Human Study
Additional Links
Diseases : Dengue, Phthalate Toxicity
Additional Keywords : Increased Risk
Problem Substances : Phthalates
Adverse Pharmacological Actions : Immunotoxic
[+]

Monocarboxyisooctyl phthalate was associated with lower respiratory health after controlling for related chemical exposureOct 17, 2018

Pubmed Data : Pediatr Allergy Immunol. 2018 Oct 18. Epub 2018 Oct 18. PMID: 30338578
Article Published Date : Oct 17, 2018
Study Type : Human Study
Additional Links
Diseases : Asthma, Bisphenol Toxicity, Phthalate Toxicity , Prenatal Chemical Exposures
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A , Phthalates
[+]

Nail technicians are occupationally exposed to certain phthalates, phthalate alternatives, and organophosphate esters.Dec 16, 2019

Pubmed Data : Environ Sci Technol. 2019 Dec 17 ;53(24):14630-14637. Epub 2019 Dec 4. PMID: 31736299
Article Published Date : Dec 16, 2019
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Organophosphates, Phthalates
[+]

Occurrence of eczema in early childhood may be influenced by prenatal exposure to certain phthalates in boys.Feb 01, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health Perspect. 2018 Feb 2 ;126(2):027002. Epub 2018 Feb 2. PMID: 29398652
Article Published Date : Feb 01, 2018
Study Type : Human Study
Additional Links
Diseases : Eczema, Phthalate Toxicity , Prenatal Chemical Exposures
Additional Keywords : eczema, Phthalate Toxicity, Phthalates, Prenatal Chemical Exposures
Problem Substances : Phthalates
[+]

Oxidative stress mediates the associations between phthalate exposures and thyroid cancer/benign nodule risk.May 31, 2023

Pubmed Data : Environ Pollut. 2023 Jun 1 ;326:121462. Epub 2023 Mar 21. PMID: 36958664
Article Published Date : May 31, 2023
Study Type : Human Study
Additional Links
Diseases : Oxidative Stress, Phthalate Toxicity , Thyroid Cancer
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Phthalate exposure and neurodevelopmental outcomes in early school age children from Poland.Nov 30, 2019

Pubmed Data : Environ Res. 2019 Dec ;179(Pt B):108829. Epub 2019 Oct 18. PMID: 31677502
Article Published Date : Nov 30, 2019
Study Type : Human Study
Additional Links
Diseases : Neurodevelopmental Disorders, Phthalate Toxicity
Problem Substances : Phthalates
Adverse Pharmacological Actions : Neurotoxic
[+]

Phthalate exposure during pregnancy and its association with thyroid hormones.Jul 31, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Hyg Environ Health. 2024 Aug ;261:114421. Epub 2024 Jul 13. PMID: 39002474
Article Published Date : Jul 31, 2024
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity , Prenatal Chemical Exposures
Problem Substances : Phthalates
[+]

Phthalate exposure enhances incidence of urinary incontinence.Apr 26, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Sci Pollut Res Int. 2022 Apr 27. Epub 2022 Apr 27. PMID: 35474427
Article Published Date : Apr 26, 2022
Study Type : Human Study
Additional Links
Diseases : Incontinence: Urinary, Phthalate Toxicity
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

Phthalate exposure increased the risk of early renal impairment in Taiwanese without type 2 diabetes mellitus.Nov 25, 2019

Pubmed Data : Int J Hyg Environ Health. 2019 Nov 26:113414. Epub 2019 Nov 26. PMID: 31784327
Article Published Date : Nov 25, 2019
Study Type : Human Study
Additional Links
Diseases : Kidney Damage: Chemically-Induced, Phthalate Toxicity
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

Phthalate exposure were associated with prostate cancer occurrence in abdominally obese men.Nov 07, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Res. 2019 Nov 8:108902. Epub 2019 Nov 8. PMID: 31785779
Article Published Date : Nov 07, 2019
Study Type : Human Study
Additional Links
Diseases : Obesity, Phthalate Toxicity , Prostate Cancer
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

Phthalate exposures and MicroRNA expression in uterine fibroids.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Epigenet Insights. 2020 ;13:2516865720904057. Epub 2020 Feb 18. PMID: 32128507
Article Published Date : Dec 31, 2019
Study Type : Human Study
Additional Links
Diseases : Fibroids: Uterine, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Phthalates exposure of MASLD adults was related to increased risks of IR, prediabetes, and diabetes.Dec 09, 2024

Pubmed Data : Diabetes Metab. 2024 Dec 10 ;51(1):101602. Epub 2024 Dec 10. PMID: 39662798
Article Published Date : Dec 09, 2024
Study Type : Human Study
Additional Links
Diseases : Insulin Resistance, Liver Disease, Phthalate Toxicity , Prediabetes
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

Prenatal concentrations of certain phthalates and outcomes at birth were modestly associated with molecular changes in fetal placental tissue during pregnancy.Apr 04, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health. 2017 Apr 5 ;16(1):35. Epub 2017 Apr 5. PMID: 28381288
Article Published Date : Apr 04, 2017
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity , Prenatal Chemical Exposures
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Prenatal exposure to environmental phenols and phthalates and altered patterns of DNA methylation in childhood.Jul 31, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Int. 2024 Aug ;190:108862. Epub 2024 Jun 30. PMID: 38972116
Article Published Date : Jul 31, 2024
Study Type : Human Study
Additional Links
Diseases : Paraben Toxicity , Phthalate Toxicity , Prenatal Chemical Exposures
Additional Keywords : DNA Methylation
Problem Substances : Parabens, Phthalates
[+]

Prenatal exposure to phthalates and emotional/behavioral development in young children.Aug 01, 2023

Pubmed Data : Neurotoxicology. 2023 Aug 2 ;98:39-47. Epub 2023 Aug 2. PMID: 37536470
Article Published Date : Aug 01, 2023
Study Type : Human Study
Additional Links
Diseases : Developmental Disorder: Children, Phthalate Toxicity , Prenatal Chemical Exposures
Problem Substances : Phthalates
[+]

Prenatal exposure to phthalates and phthalate replacements in relation to chorionic plate surface vasculature at delivery.Dec 16, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Total Environ. 2024 Dec 17 ;958:178116. Epub 2024 Dec 17. PMID: 39693655
Article Published Date : Dec 16, 2024
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity , Prenatal Chemical Exposures
Problem Substances : Phthalates
[+]

Prenatal phthalate metabolite concentrations were associated with respiratory outcomes in childhood.Sep 15, 2024

Pubmed Data : Sci Total Environ. 2024 Sep 16:176311. Epub 2024 Sep 16. PMID: 39293757
Article Published Date : Sep 15, 2024
Study Type : Human Study
Additional Links
Diseases : Asthma, Phthalate Toxicity , Wheezing: Infants
Problem Substances : Phthalates
[+]

Relationships among phthalate exposure, oxidative stress, and insulin resistance in young military soldiers.May 22, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Int. 2022 May 23 ;165:107316. Epub 2022 May 23. PMID: 35635958
Article Published Date : May 22, 2022
Study Type : Human Study
Additional Links
Diseases : Insulin Resistance, Oxidative Stress, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

The effects of phthalate exposure on metabolic parameters in polycystic ovary syndrome.Jan 06, 2023

Pubmed Data : Clin Chim Acta. 2023 Jan 7:117225. Epub 2023 Jan 7. PMID: 36627009
Article Published Date : Jan 06, 2023
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity , Polycystic Ovary Syndrome
Problem Substances : Phthalates
[+]

The phthalate exposure in the first trimester might be associated with the fasting blood glucose level in the third trimesterMar 09, 2017

Pubmed Data : Zhonghua Liu Xing Bing Xue Za Zhi. 2017 Mar 10 ;38(3):388-392. PMID: 28329946
Article Published Date : Mar 09, 2017
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
[+]

The present study suggests that dimethyl phthalate exposure increases the risk of high blood pressure.Jul 16, 2020

Pubmed Data : Environ Int. 2020 Jul 17 ;143:105958. Epub 2020 Jul 17. PMID: 32688158
Article Published Date : Jul 16, 2020
Study Type : Human Study
Additional Links
Diseases : Hypertension, Phthalate Toxicity
Problem Substances : Phthalates
[+]

The present study suggests that prenatal exposure to PAEs was positively correlated with increased blood pressure in pre-school children.Dec 18, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2024 Dec 19 ;290:117553. Epub 2024 Dec 19. PMID: 39705975
Article Published Date : Dec 18, 2024
Study Type : Human Study
Additional Links
Diseases : Hypertension, Phthalate Toxicity , Prenatal Chemical Exposures
Problem Substances : Phthalates
[+]

The relationship between bisphenol A and phthalates with precocious puberty in Vietnamese children.Jun 03, 2024

Pubmed Data : J Pediatr Endocrinol Metab. 2024 Jun 4. Epub 2024 Jun 4. PMID: 38829694
Article Published Date : Jun 03, 2024
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Phthalate Toxicity , Puberty: Precocious
Problem Substances : Bisphenol A , Phthalates
[+]

The role of Di(2-ethylhexyl) phthalate as an exacerbating factor in chronic spontaneous urticaria.Apr 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Allergy Asthma Immunol Res. 2022 May ;14(3):339-343. PMID: 35557498
Article Published Date : Apr 30, 2022
Study Type : Human Study
Additional Links
Diseases : Asthma, Phthalate Toxicity , Urticaria
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

There was an association between total phthalate concentration and non-communicable diseases and chronic inflammation in men.Jul 03, 2017

Pubmed Data : Environ Res. 2017 Jul 4 ;158:366-372. Epub 2017 Jul 4. PMID: 28686951
Article Published Date : Jul 03, 2017
Study Type : Human Study
Additional Links
Diseases : Cardiovascular Diseases, Diabetes Mellitus: Type 2, Hypertension, Inflammation, Phthalate Toxicity
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

These findings indicate that prenatal endocrine-disrupting chemicals exposures are associated with sex-specific deviations in biological aging.Aug 09, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Epigenomes. 2024 Aug 10 ;8(3). Epub 2024 Aug 10. PMID: 39189257
Article Published Date : Aug 09, 2024
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Phthalate Toxicity , Prenatal Chemical Exposures
Additional Keywords : Epigenetic Age Acceleration
Problem Substances : Phthalates
[+]

These findings suggest associations of prenatal exposure to DINP with decreased masculine play behavior in boys.Jul 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Int. 2023 Aug ;178:108029. Epub 2023 Jun 13. PMID: 37331180
Article Published Date : Jul 31, 2023
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity , Prenatal Chemical Exposures
Problem Substances : Phthalates
[+]

These findings suggest that prenatal and postnatal exposure to dibutyl phthalate (DBP), metabolized as MnBP, distinctly affects children's behavioral development.Oct 30, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxics. 2024 Oct 31 ;12(11). Epub 2024 Oct 31. PMID: 39590974
Article Published Date : Oct 30, 2024
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity , Prenatal Chemical Exposures
Problem Substances : Phthalates
[+]

These results also suggested that serum levels of phthalate metabolites are a good predictor for male infertility.Jul 10, 2020

Pubmed Data : Sci Total Environ. 2020 Jul 11 ;744:140673. Epub 2020 Jul 11. PMID: 32702538
Article Published Date : Jul 10, 2020
Study Type : Human Study
Additional Links
Diseases : Infertility: Male, Phthalate Toxicity
Problem Substances : Phthalates
[+]

These results are consistent with the hypothesis that exposure to phthalates influences thyroid function and growth hormone homeostasis.Jan 31, 2017

Pubmed Data : Environ Res. 2017 Feb ;153:63-72. Epub 2016 Nov 29. PMID: 27907809
Article Published Date : Jan 31, 2017
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Phthalate Toxicity
Problem Substances : Bisphenol A , Phthalates
[+]

These results may provide evidence for the hypothesis that reductions in thyroid hormones mediate associations between early life phthalate exposures.Aug 31, 2017

Pubmed Data : Environ Int. 2017 Sep ;106:11-18. Epub 2017 May 27. PMID: 28554096
Article Published Date : Aug 31, 2017
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
[+]

This study reveals a more elevated occupational intake of phthalate and non-phthalate plasticizers through the indoor dust at salons than at homes.Jul 16, 2017

Pubmed Data : Environ Pollut. 2017 Jul 17 ;230:701-708. Epub 2017 Jul 17. PMID: 28728088
Article Published Date : Jul 16, 2017
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
[+]

Time course of phthalate cumulative risks to male developmental health over a 27-year period.Feb 04, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Int. 2020 Feb 5 ;137:105467. Epub 2020 Feb 5. PMID: 32036120
Article Published Date : Feb 04, 2020
Study Type : Human Study
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
[+]

Ultra-processed food consumption may increase exposure to currently used phthalates.Jan 09, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Int. 2019 10 ;131:105057. Epub 2019 Aug 6. PMID: 31398592
Article Published Date : Jan 09, 2019
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Phthalate Toxicity
Additional Keywords : Canned Food, processed food
Problem Substances : Bisphenol A , Bisphenol F, Phthalates
[+]

Urinary phthalate exposures and risk of breast cancer: the Multiethnic Cohort study.Apr 05, 2021

Pubmed Data : Breast Cancer Res. 2021 Apr 6 ;23(1):44. Epub 2021 Apr 6. PMID: 33823904
Article Published Date : Apr 05, 2021
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

β-carotene could protect against di-2-ethylhexyl phthalate induced insulin resistance.Oct 31, 2019

Pubmed Data : Environ Res. 2019 Nov ;178:108729. Epub 2019 Sep 8. PMID: 31521963
Article Published Date : Oct 31, 2019
Study Type : Human Study
Additional Links
Substances : beta-Carotene
Diseases : Insulin Resistance, Phthalate Toxicity
Pharmacological Actions : Cytoprotective
Problem Substances : Phthalates
[+]

Environmental pollutant Di-(2-ethylhexyl) phthalate induces asthenozoospermia.Sep 10, 2024

Pubmed Data : Mol Divers. 2024 Sep 11. Epub 2024 Sep 11. PMID: 39259422
Article Published Date : Sep 10, 2024
Study Type : Human In Vitro
Additional Links
Diseases : Asthenozoospermia, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Face mask-A potential source of phthalate exposure for human.Jan 14, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Hazard Mater. 2022 Jan 15 ;422:126848. Epub 2021 Aug 6. PMID: 34403943
Article Published Date : Jan 14, 2022
Study Type : Human In Vitro
Additional Links
Diseases : Phthalate Toxicity
Additional Keywords : Risk Factors
Anti Therapeutic Actions : Face Masks: Cloth
Problem Substances : Phthalates
[+]

The present study demonstrates preliminary information regarding the low dose proliferative effects of phthalates in prostate cancer in vitro.Dec 31, 2016

Pubmed Data : Bratisl Lek Listy. 2017 ;118(8):460-466. PMID: 29050483
Article Published Date : Dec 31, 2016
Study Type : Human In Vitro
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Phthalate Toxicity , Prostate Cancer
Problem Substances : Phthalates
[+]

Bisphenol A and Di(2-Ethylhexyl) Phthalate promote pulmonary carcinoma.Jan 14, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2023 Jan 15 ;250:114496. Epub 2023 Jan 4. PMID: 36608567
Article Published Date : Jan 14, 2023
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity, Lung Cancer, Phthalate Toxicity
Problem Substances : Bisphenol A , Phthalates
[+]

DEHP-mediated oxidative stress leads to impaired testosterone synthesis in Leydig cells.Dec 07, 2024

Pubmed Data : Environ Pollut. 2024 Dec 8 ;366:125503. Epub 2024 Dec 8. PMID: 39657860
Article Published Date : Dec 07, 2024
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Low Testosterone, Oxidative Stress, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Administration of celery oil protected the testis against DEHP induced toxicity.Aug 31, 2014

Pubmed Data : Reprod Biol. 2014 Sep ;14(3):182-9. Epub 2014 Apr 21. PMID: 25152515
Article Published Date : Aug 31, 2014
Study Type : Animal Study
Additional Links
Substances : Celery Oil
Diseases : Phthalate Toxicity
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
Problem Substances : Phthalates
[+]

Altered gut microbiota community structure and correlated immune system changes in dibutyl phthalate exposed mice.Aug 04, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2023 Aug 5 ;262:115321. Epub 2023 Aug 5. PMID: 37549549
Article Published Date : Aug 04, 2023
Study Type : Animal Study
Additional Links
Diseases : Dysbiosis, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Antoxidants can protect the testes from phthalate induced toxicity. Apr 01, 2000

Pubmed Data : Int J Androl. 2000 Apr;23(2):85-94. PMID: 10762434
Article Published Date : Apr 01, 2000
Study Type : Animal Study
Additional Links
Substances : Antioxidant formulas
Diseases : Phthalate Toxicity
[+]

Ascorbic acid ameliorates dysregulated folliculogenesis induced by mono-(2-ethylhexyl)phthalate in neonatal mouse ovaries.Aug 02, 2020

Pubmed Data : Reprod Domest Anim. 2020 Aug 3. Epub 2020 Aug 3. PMID: 32744352
Article Published Date : Aug 02, 2020
Study Type : Animal Study
Additional Links
Substances : Vitamin C
Diseases : Phthalate Toxicity
Pharmacological Actions : Antioxidants
Problem Substances : Phthalates
[+]

Celery oil seed extract ameliorated the toxicological effects of DEHP in rats.Mar 31, 2015

Pubmed Data : Toxicol Ind Health. 2015 Apr ;31(4):355-66. Epub 2013 Feb 1. PMID: 23377116
Article Published Date : Mar 31, 2015
Study Type : Animal Study
Additional Links
Substances : Celery Oil, Celery seed
Diseases : Phthalate Toxicity
Pharmacological Actions : Hepatoprotective, Hypolipidemic
Additional Keywords : Plant Extracts
Problem Substances : Phthalates
[+]

Co-exposure to polystyrene microplastics and di-(2-ethylhexyl) phthalate aggravates allergic asthma.Jul 31, 2023

Pubmed Data : Toxicol Lett. 2023 Aug 1 ;384:73-85. Epub 2023 Jul 26. PMID: 37500026
Article Published Date : Jul 31, 2023
Study Type : Animal Study
Additional Links
Diseases : Asthma, Microplastic Toxicity, Phthalate Toxicity
Additional Keywords : Synergistic Toxicity
Problem Substances : Phthalates, Polystyrene nanoparticles
[+]

Combined effect of polystyrene nanoplastic and di-n-butyl phthalate on testicular health of male Swiss albino mice.Mar 31, 2024

Pubmed Data : Environ Sci Pollut Res Int. 2024 Apr ;31(16):23680-23696. Epub 2024 Mar 1. PMID: 38427170
Article Published Date : Mar 31, 2024
Study Type : Animal Study
Additional Links
Diseases : Microplastic Toxicity, Phthalate Toxicity
Pharmacological Actions : Antioxidants
Additional Keywords : Synergistic Toxicity
Problem Substances : Nano Plastic-and Micro-Particles, Phthalates, Polystyrene nanoparticles
[+]

Curcumin (from Turmeric) and kolaviron (a compound from the seeds of Garcinia kola) ameliorate phthalate-induced testicular damage in rats. Jan 01, 2007

Pubmed Data : Basic Clin Pharmacol Toxicol. 2007 Jan;100(1):43-8. PMID: 17214610
Article Published Date : Jan 01, 2007
Study Type : Animal Study
Additional Links
Substances : Curcumin, Garcinia kola
Diseases : Phthalate Toxicity
[+]

Curcumin and resveratrol may be useful potential agents in combating DEHP-induced testicular dysfunction.Sep 07, 2015

Pubmed Data : Gen Comp Endocrinol. 2015 Sep 8. Epub 2015 Sep 8. PMID: 26361869
Article Published Date : Sep 07, 2015
Study Type : Animal Study
Additional Links
Substances : Curcumin, Resveratrol
Diseases : Phthalate Toxicity
Pharmacological Actions : Chemoprotective Agents, Heat Shock Protein Inducer, Nrf2 activation
Additional Keywords : Gene Expression
Problem Substances : Phthalates
[+]

Curcumin decreases dibutyl phthalate-induced renal dysfunction in Kunming mice via inhibiting oxidative stress and apoptosis.Mar 16, 2021

Pubmed Data : Hum Exp Toxicol. 2021 Mar 17:9603271211001124. Epub 2021 Mar 17. PMID: 33729022
Article Published Date : Mar 16, 2021
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Kidney Damage: Chemically-Induced, Phthalate Toxicity
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Renoprotective
Problem Substances : Phthalates
[+]

Curcumin suppressed phthalate-induced cell migration, invasion and epithelial-mesenchymal transition, decreased the proportion of CSC-like cells.Nov 19, 2015

Pubmed Data : J Agric Food Chem. 2015 Nov 20. Epub 2015 Nov 20. PMID: 26585812
Article Published Date : Nov 19, 2015
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Liver Cancer, Liver Cancer: Metastatic, Phthalate Toxicity
Pharmacological Actions : Anti-metastatic
Additional Keywords : Cancer Stem Cells
Problem Substances : Phthalates
Adverse Pharmacological Actions : Carcinogenic
[+]

Cytoprotective potency of naringin against di-n-butylphthalate (DBP)-induced oxidative testicular damage.Dec 12, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2023 Dec 13. Epub 2023 Dec 13. PMID: 38091078
Article Published Date : Dec 12, 2023
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Phthalate Toxicity , Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Antioxidants
Problem Substances : Phthalates
[+]

Di-(2-ethylhexyl) phthalate (DEHP) promoted hepatic lipid accumulation.Jun 30, 2023

Pubmed Data : Environ Toxicol. 2023 Jul ;38(7):1628-1640. Epub 2023 Mar 29. PMID: 36988346
Article Published Date : Jun 30, 2023
Study Type : Animal Study
Additional Links
Diseases : Inflammation, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Di-(2-ethylhexyl) phthalate aggravates fine particulate matter-induced asthma.Jan 14, 2023

Pubmed Data : Toxicology. 2023 Jan 15 ;484:153406. Epub 2022 Dec 19. PMID: 36549504
Article Published Date : Jan 14, 2023
Study Type : Animal Study
Additional Links
Diseases : Air Pollution Linked Toxicity, Asthma, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Di-(2-ethylhexyl) phthalate exacerbated the toxicity of polystyrene nanoplastics.Jun 30, 2022

Pubmed Data : Water Res. 2022 Jul 1 ;219:118608. Epub 2022 May 16. PMID: 35605397
Article Published Date : Jun 30, 2022
Study Type : Animal Study
Additional Links
Diseases : Microplastic Toxicity, Phthalate Toxicity
Additional Keywords : Synergistic Toxicity
Problem Substances : Phthalates, Polystyrene nanoparticles
[+]

Di-(2-ethylhexyl) phthalate exposure impairs cortical development in hESC-derived cerebral organoids.Dec 28, 2022

Pubmed Data : Sci Total Environ. 2022 Dec 29:161251. Epub 2022 Dec 29. PMID: 36587670
Article Published Date : Dec 28, 2022
Study Type : Animal Study
Additional Links
Diseases : Phthalate Toxicity , Prenatal Chemical Exposures
Problem Substances : Phthalates
[+]

Di-(2-ethylhexyl) phthalate exposure induces female reproductive toxicity.Mar 03, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Toxicol. 2021 Mar 4. Epub 2021 Mar 4. PMID: 33665894
Article Published Date : Mar 03, 2021
Study Type : Animal Study
Additional Links
Diseases : Infertility: Female, Phthalate Toxicity
Problem Substances : Phthalates
Adverse Pharmacological Actions : Gastrotoxic
[+]

Di-2-ethylhexyl phthalate (DEHP) induced lipid metabolism disorder in liver.May 06, 2022

Pubmed Data : Food Chem Toxicol. 2022 May 7 ;165:113119. Epub 2022 May 7. PMID: 35537648
Article Published Date : May 06, 2022
Study Type : Animal Study
Additional Links
Diseases : Chemically-Induced Liver Damage, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Di-2-ethylhexyl phthalate imposes acute and profound damage to spermatozoaDec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Cell Dev Biol. 2020 ;8:426. Epub 2020 Jun 30. PMID: 32695775
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Diseases : Infertility: Male, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Di-n-butyl phthalate diminishes testicular steroidogenesis.Feb 28, 2021

Pubmed Data : Reprod Fertil Dev. 2021 Mar ;33(5):319-327. PMID: 33632378
Article Published Date : Feb 28, 2021
Study Type : Animal Study
Additional Links
Diseases : Phthalate Toxicity , Testicular Injury: Chemical/Metal Induced
Problem Substances : Phthalates
[+]

Dibutyl phthalate-induced oxidative stress and apoptosis in swine testis cells and therapy of naringenin.Mar 31, 2022

Pubmed Data : Environ Toxicol. 2022 Apr 1. Epub 2022 Apr 1. PMID: 35363423
Article Published Date : Mar 31, 2022
Study Type : Animal Study
Additional Links
Substances : Naringenin
Diseases : Phthalate Toxicity , Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Anti-Apoptotic, Antioxidants
Problem Substances : Phthalates
[+]

Diisodecyl phthalate exacerbated allergic dermatitis through oxidative stress and enhanced TSLP production.Nov 17, 2016

Pubmed Data : Food Chem Toxicol. 2016 Nov 18. Epub 2016 Aug 18. PMID: 27871981
Article Published Date : Nov 17, 2016
Study Type : Animal Study
Additional Links
Diseases : Dermatitis, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Diisooctyl phthalate (DIOP) exposure leads to cell apoptosis to HUVEC cells and toxicity to Caenorhabditis elegans through increasing the oxidative stress.Dec 25, 2024

Pubmed Data : Ecotoxicol Environ Saf. 2024 Dec 26 ;290:117594. Epub 2024 Dec 26. PMID: 39729937
Article Published Date : Dec 25, 2024
Study Type : Animal Study
Additional Links
Diseases : Oxidative Stress, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Dipropyl phthalate induces craniofacial chondrogenic defects in zebrafish embryos.Dec 23, 2024

Pubmed Data : Ecotoxicol Environ Saf. 2024 Dec 24 ;290:117603. Epub 2024 Dec 24. PMID: 39721426
Article Published Date : Dec 23, 2024
Study Type : Animal Study
Additional Links
Diseases : Phthalate Toxicity , Prenatal Chemical Exposures
Problem Substances : Phthalates
[+]

Early-life exposure to di(2-ethylhexyl) phthalate impairs reproduction in adult female zebrafish.Nov 28, 2024

Pubmed Data : Comp Biochem Physiol C Toxicol Pharmacol. 2024 Nov 29 ;289:110090. Epub 2024 Nov 29. PMID: 39617312
Article Published Date : Nov 28, 2024
Study Type : Animal Study
Additional Links
Diseases : Phthalate Toxicity , Prenatal Chemical Exposures
Problem Substances : Phthalates
[+]

Effect of aqueous garlic extract against di-(2-ethylhexyl) phthalate induced reproductive toxicity in male mice.Jun 06, 2022

Pubmed Data : Andrologia. 2022 Jun 7:e14480. Epub 2022 Jun 7. PMID: 35670728
Article Published Date : Jun 06, 2022
Study Type : Animal Study
Additional Links
Substances : Garlic
Diseases : Phthalate Toxicity , Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Hypolipidemic
Problem Substances : Phthalates
[+]

Effects of Lactobacillus salivarius ssp. salicinius SA-03 supplementation on reversing phthalate-induced asthma.Apr 12, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2024 Apr 13 ;16(8). Epub 2024 Apr 13. PMID: 38674852
Article Published Date : Apr 12, 2024
Study Type : Animal Study
Additional Links
Substances : Lactobacillus salivarius
Diseases : Asthma, Phthalate Toxicity
Pharmacological Actions : Anti-Asthmatic Agents, Anti-Inflammatory Agents
Problem Substances : Phthalates
[+]

Effects of Lycium barbarum glycopeptide on renal and testicular injury induced by di(2-ethylhexyl) phthalate.Mar 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Stress Chaperones. 2022 Apr 1. Epub 2022 Apr 1. PMID: 35362893
Article Published Date : Mar 31, 2022
Study Type : Animal Study
Additional Links
Substances : Goji
Diseases : Phthalate Toxicity , Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Anti-Inflammatory Agents
Problem Substances : Phthalates
[+]

Effects of phthalates on the functions and fertility of mouse spermatozoa Mar 08, 2021

Pubmed Data : Toxicology. 2021 Mar 9 ;454:152746. Epub 2021 Mar 9. PMID: 33711355
Article Published Date : Mar 08, 2021
Study Type : Animal Study
Additional Links
Diseases : Infertility: Male, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Embryonic exposures to mono-2-ethylhexyl phthalate induce larval steatosis in zebrafish independent of Nrf2a signaling.Feb 16, 2020

Pubmed Data : J Dev Orig Health Dis. 2020 Feb 17:1-9. Epub 2020 Feb 17. PMID: 32063256
Article Published Date : Feb 16, 2020
Study Type : Animal Study
Additional Links
Diseases : Hepatic Steatosis, Phthalate Toxicity , Prenatal Chemical Exposures
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Environmental chemical diethylhexyl phthalate alters intestinal microbiota community structure and metabolite profile in mice.Dec 09, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : mSystems. 2019 Dec 10 ;4(6). Epub 2019 Dec 10. PMID: 31822602
Article Published Date : Dec 09, 2019
Study Type : Animal Study
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
[+]

Environmentally relevant exposure to dibutyl phthalate disrupts DNA damage repair gene expression in the mouse ovary.Jul 17, 2019

Pubmed Data : Biol Reprod. 2019 Jul 18. Epub 2019 Jul 18. PMID: 31318015
Article Published Date : Jul 17, 2019
Study Type : Animal Study
Additional Links
Diseases : Infertility: Female, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Exposure to phthalates DEHP and DINP May lead to oxidative damage and lipidomic disruptions in mouse kidney.Apr 30, 2021

Pubmed Data : Chemosphere. 2021 May ;271:129740. Epub 2021 Jan 22. PMID: 33736212
Article Published Date : Apr 30, 2021
Study Type : Animal Study
Additional Links
Diseases : Kidney Damage: Chemically-Induced, Oxidative Stress, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Gestational exposure to an epidemiologically defined mixture of phthalates leads to gonadal dysfunction in mouse offspring of both sexes.Apr 22, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2019 Apr 23 ;9(1):6424. Epub 2019 Apr 23. PMID: 31015488
Article Published Date : Apr 22, 2019
Study Type : Animal Study
Additional Links
Diseases : Female Reproductive Development Abnormalities, Male Reproductive Development Abnormalities, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Green tea polyphenols alleviate di (2-ethylhexyl) phthalate-induced testicular injury.Dec 09, 2024

Pubmed Data : Biol Reprod. 2024 Dec 10. Epub 2024 Dec 10. PMID: 39658192
Article Published Date : Dec 09, 2024
Study Type : Animal Study
Additional Links
Substances : Green Tea, Polyphenols
Diseases : Phthalate Toxicity , Testicular Injury: Chemical/Metal Induced
Problem Substances : Phthalates
[+]

Gut microbiota dysbiosis might be responsible to different toxicity caused by Di-(2-ethylhexyl) phthalate exposure in murine rodents.Feb 13, 2020

Pubmed Data : Environ Pollut. 2020 Feb 14 ;261:114164. Epub 2020 Feb 14. PMID: 32088434
Article Published Date : Feb 13, 2020
Study Type : Animal Study
Additional Links
Diseases : Dysbiosis, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

High-fat diet may have a joint effect with DEHP on lipid metabolism disorder.Dec 04, 2019

Pubmed Data : Environ Sci Pollut Res Int. 2019 Dec 5. Epub 2019 Dec 5. PMID: 31732953
Article Published Date : Dec 04, 2019
Study Type : Animal Study
Additional Links
Diseases : High Fat Diet, Phthalate Toxicity
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

Investigation into the protective effects of Naringenin in phthalates-induced reproductive damage.Apr 30, 2022

Pubmed Data : Eur Rev Med Pharmacol Sci. 2022 May ;26(10):3419-3429. PMID: 35647821
Article Published Date : Apr 30, 2022
Study Type : Animal Study
Additional Links
Substances : Naringenin
Diseases : Phthalate Toxicity , Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Antioxidants
Problem Substances : Phthalates
[+]

Long-term dietary administration of diethyl phthalate triggers loss of insulin sensitivity in two key insulin target tissues of mice.Mar 03, 2020

Pubmed Data : Hum Exp Toxicol. 2020 Mar 4:960327120909526. Epub 2020 Mar 4. PMID: 32129097
Article Published Date : Mar 03, 2020
Study Type : Animal Study
Additional Links
Diseases : Diabetes Mellitus: Type 2, Insulin Resistance, Metabolic Diseases, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Low dose of genistein alleviates phthalate-induced fetal testis disorder.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2020 ;2020:4569268. Epub 2020 May 27. PMID: 32566080
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Genistein
Diseases : Phthalate Toxicity , Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Antioxidants
Problem Substances : Phthalates
[+]

Lycium barbarum polysaccharides and Wolfberry juice prevent DEHP-induced hepatotoxicity.Feb 05, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2021 Feb 6 ;26(4). Epub 2021 Feb 6. PMID: 33562043
Article Published Date : Feb 05, 2021
Study Type : Animal Study
Additional Links
Substances : Goji
Diseases : Chemically-Induced Liver Damage, Phthalate Toxicity
Pharmacological Actions : Hepatoprotective
Additional Keywords : Polysaccharides
Problem Substances : Phthalates
[+]

Lycopene ameliorates DEHP exposure-induced renal pyroptosis.Jan 03, 2023

Pubmed Data : J Nutr Biochem. 2023 Jan 4:109266. Epub 2023 Jan 4. PMID: 36610486
Article Published Date : Jan 03, 2023
Study Type : Animal Study
Additional Links
Substances : Lycopene
Diseases : Kidney Damage: Chemically-Induced, Phthalate Toxicity
Pharmacological Actions : Antioxidants, Nrf2 activation, Renoprotective
Problem Substances : Phthalates
[+]

Lycopene attenuates Di(2-ethylhexyl) phthalate-induced mitochondrial damage and inflammation in kidney.Jan 10, 2023

Pubmed Data : J Agric Food Chem. 2023 Jan 11 ;71(1):569-579. Epub 2022 Dec 30. PMID: 36583613
Article Published Date : Jan 10, 2023
Study Type : Animal Study
Additional Links
Substances : Lycopene
Diseases : Inflammation, Kidney Damage: Chemically-Induced, Phthalate Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Renoprotective
Problem Substances : Phthalates
[+]

Lycopene attenuates di(2-ethylhexyl) phthalate-induced mitophagy in spleen by regulating the sirtuin3-mediated pathway.May 20, 2021

Pubmed Data : Food Funct. 2021 May 21 ;12(10):4582-4590. Epub 2021 Apr 28. PMID: 33908429
Article Published Date : May 20, 2021
Study Type : Animal Study
Additional Links
Substances : Lycopene
Diseases : Phthalate Toxicity
Pharmacological Actions : Anti-Inflammatory Agents
Problem Substances : Phthalates
[+]

Lycopene prevents DEHP-induced liver lipid metabolism disorder.Oct 13, 2020

Pubmed Data : J Agric Food Chem. 2020 Oct 14 ;68(41):11468-11479. Epub 2020 Oct 5. PMID: 32962341
Article Published Date : Oct 13, 2020
Study Type : Animal Study
Additional Links
Substances : Lycopene
Diseases : Chemically-Induced Liver Damage, Phthalate Toxicity
Pharmacological Actions : Hepatoprotective, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
Problem Substances : Phthalates
[+]

Lycopene prevents Di-(2-ethylhexyl) phthalate-induced mitophagy and oxidative stress in mice heart.Apr 30, 2023

Pubmed Data : J Nutr Biochem. 2023 May ;115:109285. Epub 2023 Feb 14. PMID: 36796548
Article Published Date : Apr 30, 2023
Study Type : Animal Study
Additional Links
Substances : Lycopene
Diseases : Mitochondrial Dysfunction , Oxidative Stress, Phthalate Toxicity
Pharmacological Actions : Antioxidants, Cardioprotective
Problem Substances : Phthalates
[+]

Lycopene prevents phthalate-Induced cognitive impairment.Oct 22, 2023

Pubmed Data : J Agric Food Chem. 2023 Oct 23. Epub 2023 Oct 23. PMID: 37871231
Article Published Date : Oct 22, 2023
Study Type : Animal Study
Additional Links
Substances : Lycopene
Diseases : Phthalate Toxicity
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Neuroprotective Agents, Nrf2 activation
Problem Substances : Phthalates
[+]

Lycopene regulates the mitochondrial unfolded protein response to prevent DEHP-induced cardiac mitochondrial damage.Apr 19, 2022

Pubmed Data : Food Funct. 2022 Apr 20 ;13(8):4527-4536. Epub 2022 Apr 20. PMID: 35348563
Article Published Date : Apr 19, 2022
Study Type : Animal Study
Additional Links
Substances : Lycopene
Diseases : Oxidative Stress, Phthalate Toxicity
Pharmacological Actions : Antioxidants, Cardioprotective, Nrf2 activation
Problem Substances : Phthalates
[+]

Maternal exposure to di-2-ethylhexyl phthalate (DEHP) depresses lactation capacity in mice.May 08, 2022

Pubmed Data : Sci Total Environ. 2022 May 9:155813. Epub 2022 May 9. PMID: 35550907
Article Published Date : May 08, 2022
Study Type : Animal Study
Additional Links
Diseases : Inflammation, Oxidative Stress, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Multi-strain probiotic ameliorated toxic effects of phthalates and bisphenol A mixture.Jul 05, 2020

Pubmed Data : Food Chem Toxicol. 2020 Jul 6:111540. Epub 2020 Jul 6. PMID: 32645469
Article Published Date : Jul 05, 2020
Study Type : Animal Study
Additional Links
Substances : Probiotics
Diseases : Bisphenol Toxicity, Phthalate Toxicity
Pharmacological Actions : Gastrointestinal Agents, Hepatoprotective, Renoprotective
Problem Substances : Bisphenol A , Phthalates
[+]

Neuro-protective potentials of N-acetylcysteine and zinc against phthalate-induced neuro-histopathology and dys-regulations of dopamine and glutamate.Dec 31, 2022

Pubmed Data : J Environ Sci Health A Tox Hazard Subst Environ Eng. 2023 ;58(1):81-90. Epub 2023 Feb 28. PMID: 36852734
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine), Zinc
Diseases : Phthalate Toxicity
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Phthalates
[+]

Nicotinamide mononucleotide restores oxidative stress-related apoptosis of oocyte exposed to benzyl butyl phthalate in mice.Jul 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Prolif. 2023 Aug ;56(8):e13419. Epub 2023 Feb 9. PMID: 36756972
Article Published Date : Jul 31, 2023
Study Type : Animal Study
Additional Links
Substances : Nicotinamide
Diseases : Oxidative Stress, Phthalate Toxicity
Pharmacological Actions : Anti-Apoptotic, Antioxidants
Problem Substances : Phthalates
[+]

Persistent immunosuppressive effects of dibutyl phthalate exposure.Jun 19, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Total Environ. 2023 Jun 20 ;878:162741. Epub 2023 Mar 11. PMID: 36914131
Article Published Date : Jun 19, 2023
Study Type : Animal Study
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
Adverse Pharmacological Actions : Immunosuppressive
[+]

Phthalate and polystyrene microplastics co-exposure caused oxidative stress to activate NF-κB/NLRP3 pathway aggravated pyroptosis and inflammation in mouse kidney.May 19, 2024

Pubmed Data : Sci Total Environ. 2024 May 20 ;926:171817. Epub 2024 Mar 19. PMID: 38513858
Article Published Date : May 19, 2024
Study Type : Animal Study
Additional Links
Diseases : Inflammation, Kidney Damage: Chemically-Induced, Microplastic Toxicity, Oxidative Stress, Phthalate Toxicity
Additional Keywords : Synergistic Toxicity
Problem Substances : Nano Plastic-and Micro-Particles, Phthalates, Polystyrene nanoparticles
[+]

Phthalate esters in dusts from different indoor and outdoor microenvironment and potential human health risk.Dec 02, 2024

Pubmed Data : Environ Res. 2024 Dec 3 ;266:120513. Epub 2024 Dec 3. PMID: 39631649
Article Published Date : Dec 02, 2024
Study Type : Environmental
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
[+]

Phthalate esters with long-term low-dose exposure may pose male reproductive toxicity in humans.Feb 28, 2017

Pubmed Data : Food Chem Toxicol. 2017 Mar ;101:94-104. Epub 2017 Jan 12. PMID: 28089693
Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Diseases : Infertility: Male, Phthalate Toxicity
Problem Substances : Phthalates
Adverse Pharmacological Actions : Teratogenic
[+]

Phthalates esters disrupt demersal fish behavior: Unveiling the brain-gut axis impact.Dec 06, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2024 Dec 7 ;289:117470. Epub 2024 Dec 7. PMID: 39647374
Article Published Date : Dec 06, 2024
Study Type : Animal Study
Additional Links
Diseases : Phthalate Toxicity
Additional Keywords : Gut-brain Axis
Problem Substances : Phthalates
[+]

Phthalates may disrupt heart rate variability and cardiovascular reactivity.Aug 24, 2017

Pubmed Data : Am J Physiol Heart Circ Physiol. 2017 Aug 25:ajpheart.00364.2017. Epub 2017 Aug 25. PMID: 28842438
Article Published Date : Aug 24, 2017
Study Type : Animal Study
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
Adverse Pharmacological Actions : Cardiotoxic
[+]

Polystyrene nanoparticles aggravate the adverse effects of di-(2-ethylhexyl) phthalate on different segments of intestine.Sep 30, 2022

Pubmed Data : Chemosphere. 2022 Oct ;305:135324. Epub 2022 Jun 11. PMID: 35697104
Article Published Date : Sep 30, 2022
Study Type : Animal Study
Additional Links
Diseases : Microplastic Toxicity, Phthalate Toxicity
Additional Keywords : Synergistic Toxicity
Problem Substances : Phthalates, Polystyrene nanoparticles
[+]

Polystyrene nanoparticles enhance the adverse effects of di-(2-ethylhexyl) phthalate on male reproductive system in mice.Oct 14, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2022 Oct 15 ;245:114104. Epub 2022 Sep 26. PMID: 36174316
Article Published Date : Oct 14, 2022
Study Type : Animal Study
Additional Links
Diseases : Infertility: Male, Microplastic Toxicity, Phthalate Toxicity
Problem Substances : Phthalates, Polystyrene nanoparticles
[+]

Polystyrene nanoplastics aggravated dibutyl phthalate-induced blood-testis barrier dysfunction.Sep 30, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2023 Oct 1 ;264:115403. Epub 2023 Aug 31. PMID: 37659273
Article Published Date : Sep 30, 2023
Study Type : Animal Study
Additional Links
Diseases : Microplastic Toxicity, Phthalate Toxicity , Testicular Injury: Chemical/Metal Induced
Problem Substances : Phthalates, Polystyrene nanoparticles
[+]

Prenatal exposure to a phthalate mixture leads to multigenerational and transgenerational effects on uterine morphology and function in mice.Feb 28, 2020

Pubmed Data : Reprod Toxicol. 2020 Feb 29. Epub 2020 Feb 29. PMID: 32126281
Article Published Date : Feb 28, 2020
Study Type : Animal Study
Additional Links
Diseases : Phthalate Toxicity , Prenatal Chemical Exposures
Additional Keywords : Transgenerational inheritance
Problem Substances : Phthalates
[+]

Prenatal exposure to an environmentally relevant phthalate mixture alters serum cytokine levels and inflammatory markers in the F1 mouse ovary.Aug 31, 2024

Pubmed Data : Toxicol Sci. 2024 Sep 1 ;201(1):26-37. PMID: 38954831
Article Published Date : Aug 31, 2024
Study Type : Animal Study
Additional Links
Diseases : Phthalate Toxicity , Prenatal Chemical Exposures
Problem Substances : Phthalates
Adverse Pharmacological Actions : Immunotoxic
[+]

Prenatal exposure to bisphenol A and/or diethylhexyl phthalate alters stress responses in rat offspring.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Toxicol. 2023 ;5:1264238. Epub 2023 Dec 13. PMID: 38152552
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity, Phthalate Toxicity , Prenatal Chemical Exposures
Additional Keywords : Synergistic Toxicity, Transgenerational inheritance
Problem Substances : Bisphenol A , Phthalates
[+]

Prenatal exposure to bisphenol A and/or diethylhexyl phthalate impacts brain monoamine levels in rat offspring.Jul 31, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Xenobiot. 2024 Aug 1 ;14(3):1036-1050. Epub 2024 Aug 1. PMID: 39189173
Article Published Date : Jul 31, 2024
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity, Phthalate Toxicity
Problem Substances : Bisphenol A , Phthalates
Adverse Pharmacological Actions : Neurotoxic
[+]

Prenatal exposure to dibutyl phthalate contributes to erectile dysfunction in male offspring.Oct 31, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxicology. 2024 Nov ;508:153925. Epub 2024 Aug 14. PMID: 39151608
Article Published Date : Oct 31, 2024
Study Type : Animal Study
Additional Links
Diseases : Erectile Dysfunction, Phthalate Toxicity , Prenatal Chemical Exposures
Problem Substances : Phthalates
[+]

Protective effect of alpha-lipoic acid on di-(2-ethylhexyl) phthalate-induced testicular toxicity in mice.Feb 06, 2020

Pubmed Data : Environ Sci Pollut Res Int. 2020 Feb 7. Epub 2020 Feb 7. PMID: 32030592
Article Published Date : Feb 06, 2020
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Phthalate Toxicity , Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Antioxidants
Problem Substances : Phthalates
[+]

Protective effect of Lycium barbarum polysaccharide on di-(2-ethylhexyl) phthalate-induced toxicity in rat liver.Jan 14, 2021

Pubmed Data : Environ Sci Pollut Res Int. 2021 Jan 15. Epub 2021 Jan 15. PMID: 33449321
Article Published Date : Jan 14, 2021
Study Type : Animal Study
Additional Links
Substances : Goji
Diseases : Phthalate Toxicity
Additional Keywords : Polysaccharides
Problem Substances : Phthalates
[+]

Quercetin has a potent protective effect against DEHP-induced testicular toxicity in rats.Apr 14, 2015

Pubmed Data : Hum Exp Toxicol. 2015 Apr 15. Epub 2015 Apr 15. PMID: 25882133
Article Published Date : Apr 14, 2015
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Oxidative Stress, Phthalate Toxicity
Pharmacological Actions : Antioxidants
Problem Substances : Phthalates
[+]

Role of mitochondria-endoplasmic reticulum coupling in lycopene preventing DEHP-induced hepatotoxicity.Oct 04, 2021

Pubmed Data : Food Funct. 2021 Oct 5. Epub 2021 Oct 5. PMID: 34608470
Article Published Date : Oct 04, 2021
Study Type : Animal Study
Additional Links
Substances : Lycopene
Diseases : Chemically-Induced Liver Damage, Phthalate Toxicity
Pharmacological Actions : Hepatoprotective
Problem Substances : Phthalates
[+]

Rutin prevents cardiac oxidative stress and inflammation induced by bisphenol A and dibutyl phthalate exposure.Aug 08, 2021

Pubmed Data : Life Sci. 2021 Aug 9:119878. Epub 2021 Aug 9. PMID: 34384828
Article Published Date : Aug 08, 2021
Study Type : Animal Study
Additional Links
Substances : Rutin
Diseases : Bisphenol Toxicity, Phthalate Toxicity
Pharmacological Actions : Antioxidants, Cardioprotective, Nrf2 activation
Problem Substances : Bisphenol A , Phthalates
[+]

Taxifolin alleviates apoptotic injury induced by DEHP exposure through cytochrome P450 homeostasis in chicken cardiomyocytes.Nov 14, 2019

Pubmed Data : Ecotoxicol Environ Saf. 2019 Nov 15 ;183:109582. Epub 2019 Aug 20. PMID: 31442803
Article Published Date : Nov 14, 2019
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Oxidative Stress, Phthalate Toxicity
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Cardioprotective
Problem Substances : Phthalates
[+]

Taxifolin ameliorates DEHP-induced cardiomyocyte hypertrophy.Nov 30, 2019

Pubmed Data : Environ Pollut. 2019 Dec ;255(Pt 1):113155. Epub 2019 Sep 11. PMID: 31539850
Article Published Date : Nov 30, 2019
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Cardiomegaly, Phthalate Toxicity
Pharmacological Actions : Cardioprotective
Problem Substances : Phthalates
[+]

Taxifolin attenuates the developmental testicular toxicity induced by di-n-butyl phthalate in fetal male rats.Jul 31, 2020

Pubmed Data : Food Chem Toxicol. 2020 Aug ;142:111482. Epub 2020 Jun 7. PMID: 32525071
Article Published Date : Jul 31, 2020
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Phthalate Toxicity , Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Antioxidants
Problem Substances : Phthalates
[+]

Tetrahydrocurcumin alleviates di-(2-ethylhexyl) phthalate-induced adipose tissue dysfunction and testicular toxicity in adult mice.Dec 19, 2024

Pubmed Data : Food Funct. 2024 Dec 20. Epub 2024 Dec 20. PMID: 39704213
Article Published Date : Dec 19, 2024
Study Type : Animal Study
Additional Links
Substances : Tetrahydrocurcumin
Diseases : Phthalate Toxicity , Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation
Problem Substances : Phthalates
[+]

The ameliorative effect of ellagic acid on di-(2-ethylhexyl) phthalate-induced testicular structural alterations.Sep 17, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Reprod Biol Endocrinol. 2021 Sep 18 ;19(1):146. Epub 2021 Sep 18. PMID: 34537068
Article Published Date : Sep 17, 2021
Study Type : Animal Study
Additional Links
Substances : Ellagic Acid
Diseases : Phthalate Toxicity , Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Problem Substances : Phthalates
[+]

The beneficial role of celery oil in lowering of di(2-ethylhexyl) phthalate-induced testicular damage.Nov 15, 2012

Pubmed Data : Toxicol Ind Health. 2012 Nov 16. Epub 2012 Nov 16. PMID: 23160384
Article Published Date : Nov 15, 2012
Study Type : Animal Study
Additional Links
Substances : Celery Oil
Diseases : Phthalate Toxicity , Testicular Diseases
[+]

The complex action of DEHP/BPA mixture may disturb the thyroid hormone homeostasis.Oct 31, 2020

Pubmed Data : Environ Sci Pollut Res Int. 2020 Nov ;27(32):40882-40892. Epub 2020 Jul 17. PMID: 32681327
Article Published Date : Oct 31, 2020
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity, Phthalate Toxicity , Thyroid Dysfunction
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A , Phthalates
[+]

The mechanism of DEHP-induced lipid accumulation in liver of female zebrafish.Dec 02, 2024

Pubmed Data : Environ Pollut. 2024 Dec 3 ;366:125455. Epub 2024 Dec 3. PMID: 39638227
Article Published Date : Dec 02, 2024
Study Type : Animal Study
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
[+]

The protective effects of thymol and carvacrol against di (2-ethylhexyl) phthalate-induced cytotoxicity in HEK-293 cells.May 05, 2022

Pubmed Data : J Biochem Mol Toxicol. 2022 May 6:e23092. Epub 2022 May 6. PMID: 35521929
Article Published Date : May 05, 2022
Study Type : Animal Study
Additional Links
Substances : Carvacrol, Thymol
Diseases : Kidney Damage: Chemically-Induced, Phthalate Toxicity
Pharmacological Actions : Antioxidants, Renoprotective
Problem Substances : Phthalates
[+]

Therapeutic efficacy of N-acetylcysteine and zinc sulphate against di-(2-ethylhexyl) phthalate-induced testicular oxido-nitrergic stress.Sep 30, 2022

Pubmed Data : Andrologia. 2022 Oct ;54(9):e14508. Epub 2022 Jul 17. PMID: 35842931
Article Published Date : Sep 30, 2022
Study Type : Animal Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine), Zinc
Diseases : Phthalate Toxicity , Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Antioxidants
Problem Substances : Phthalates
[+]

These findings established that Di-(2-ethylhexyl) phthalate exposure could promote benign prostatic hyperplasia.Jul 31, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2024 Aug ;281:116602. Epub 2024 Jun 28. PMID: 38944010
Article Published Date : Jul 31, 2024
Study Type : Animal Study
Additional Links
Diseases : Phthalate Toxicity , Prostatic Hyperplasia: Benign
Problem Substances : Phthalates
[+]

Toxic effects of dibutyl phthalate on testes of adult zebrafish: evaluation of oxidative stress parameters and histopathology.Aug 31, 2024

Pubmed Data : Environ Sci Pollut Res Int. 2024 Sep ;31(43):55610-55623. Epub 2024 Sep 6. PMID: 39237826
Article Published Date : Aug 31, 2024
Study Type : Animal Study
Additional Links
Diseases : Oxidative Stress, Phthalate Toxicity , Testicular Injury: Chemical/Metal Induced
Problem Substances : Phthalates
[+]

Toxic effects of the mixture of phthalates and bisphenol A-subacute oral toxicity study in rats.Jan 22, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2020 Jan 23 ;17(3). Epub 2020 Jan 23. PMID: 31979393
Article Published Date : Jan 22, 2020
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity, Phthalate Toxicity
Additional Keywords : Increased Risk
Problem Substances : Bisphenol A , Phthalates
[+]

Toxicity assessment of di(2-ethylhexyl) phthalate using zebrafish embryos: Cardiotoxic potential.Jun 03, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Comp Biochem Physiol C Toxicol Pharmacol. 2024 Jun 4 ;283:109956. Epub 2024 Jun 4. PMID: 38838795
Article Published Date : Jun 03, 2024
Study Type : Animal Study
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
Adverse Pharmacological Actions : Cardiotoxic
[+]

Vanillic acid ameliorates diethyl phthalate and bisphenol S-induced oxidative stress and neuroinflammation.Oct 31, 2024

Pubmed Data : J Biochem Mol Toxicol. 2024 Nov ;38(11):e70017. PMID: 39415675
Article Published Date : Oct 31, 2024
Study Type : Animal Study
Additional Links
Substances : Vanillic Acid
Diseases : Bisphenol Toxicity, Brain Inflammation , Oxidative Stress, Phthalate Toxicity
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Bisphenol S, Phthalates
[+]

Vanillic acid and Vitamin C supplementation attenuated the toxic effects of DEHP on the testicular functions.Jul 31, 2022

Pubmed Data : Reprod Fertil. 2022 Aug 1. Epub 2022 Aug 1. PMID: 35980228
Article Published Date : Jul 31, 2022
Study Type : Animal Study
Additional Links
Substances : Vitamin C
Diseases : Phthalate Toxicity , Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Antioxidants
Problem Substances : Phthalates
[+]

Vitamin C mitigates hematological and biochemical alterations caused by di(2-ethylhexyl) phthalate toxicity.Oct 06, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Comp Clin Path. 2022 Oct 7:1-12. Epub 2022 Oct 7. PMID: 36247333
Article Published Date : Oct 06, 2022
Study Type : Animal Study
Additional Links
Substances : Vitamin C
Diseases : Phthalate Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Malondialdehyde Down-regulation
Problem Substances : Phthalates
[+]

Vitamin E and curcumin can alleviate dibutyl phthalate-induced splenic injury.Nov 07, 2019

Pubmed Data : Food Chem Toxicol. 2019 Nov 8:110955. Epub 2019 Nov 8. PMID: 31712109
Article Published Date : Nov 07, 2019
Study Type : Animal Study
Additional Links
Substances : Curcumin, Vitamin E
Diseases : Oxidative Stress, Phthalate Toxicity
Pharmacological Actions : Immunomodulatory
Problem Substances : Phthalates
[+]

Vitamin E may ameliorate phthlate-induced oxidative stress in the liver and blood. Jan 01, 1998

Pubmed Data : Vox Sang. 1998;75(2):139-44. PMID: 9784668
Article Published Date : Jan 01, 1998
Study Type : Animal Study
Additional Links
Substances : Vitamin E
Diseases : Phthalate Toxicity
[+]

Bisphenols and phthalates: Plastic chemical exposures can contribute to adverse cardiovascular health outcomes.Jul 20, 2020

Pubmed Data : Birth Defects Res. 2020 Jul 21. Epub 2020 Jul 21. PMID: 32691967
Article Published Date : Jul 20, 2020
Study Type : Review
Additional Links
Diseases : Bisphenol Toxicity, Phthalate Toxicity
Problem Substances : Bisphenol A , Phthalates
Adverse Pharmacological Actions : Cardiotoxic
[+]

Didymin reverses phthalate ester-associated breast cancer aggravation in the breast cancer tumor microenvironment.Jan 31, 2016

Pubmed Data : Oncol Lett. 2016 Feb ;11(2):1035-1042. Epub 2015 Dec 7. PMID: 26893687
Article Published Date : Jan 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Breast Cancer, Phthalate Toxicity
Pharmacological Actions : Anti-metastatic, Antiproliferative
Additional Keywords : Tumor Microenvironment
Problem Substances : Phthalates
[+]

Adsorption characterization of Lactobacillus sp. for Di-(2-ethylhexyl) phthalate.Mar 29, 2023

Pubmed Data : Probiotics Antimicrob Proteins. 2023 Mar 30. Epub 2023 Mar 30. PMID: 36995550
Article Published Date : Mar 29, 2023
Study Type : In Vitro Study
Additional Links
Substances : Lactobacillus plantarum, Lactobacillus rhamnosus GG
Diseases : Phthalate Toxicity
Pharmacological Actions : Detoxifier
[+]

Antioxidants in mitigating phthalate-induced male reproductive toxicity.Sep 05, 2024

Pubmed Data : Chemosphere. 2024 Sep 6 ;364:143297. Epub 2024 Sep 6. PMID: 39245218
Article Published Date : Sep 05, 2024
Study Type : Review
Additional Links
Substances : Ellagic Acid
Diseases : Infertility: Male, Phthalate Toxicity
Pharmacological Actions : Antioxidants, Nrf2 activation
Problem Substances : Phthalates
[+]

Association between phthalate exposure and obesity risk.Aug 04, 2023

Pubmed Data : Environ Toxicol Pharmacol. 2023 Aug 5 ;102:104240. Epub 2023 Aug 5. PMID: 37549759
Article Published Date : Aug 04, 2023
Study Type : Review
Additional Links
Diseases : Obesity, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Association between the Exposure to Phthalates and the Risk of Endometriosis.Aug 21, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomedicines. 2024 Aug 22 ;12(8). Epub 2024 Aug 22. PMID: 39200395
Article Published Date : Aug 21, 2024
Study Type : Review
Additional Links
Diseases : Endometriosis, Phthalate Toxicity
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

Benzyl butyl phthalate exposure may disturb neural tube development by strengthening oxidative stress.May 31, 2020

Pubmed Data : Toxicol Res (Camb). 2020 Jun ;9(3):222-229. Epub 2020 May 8. PMID: 32670553
Article Published Date : May 31, 2020
Study Type : In Vitro Study
Additional Links
Diseases : Oxidative Stress, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Bisphenol A drives di(2-ethylhexyl) phthalate promoting thyroid tumorigenesis.Jan 04, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Hazard Mater. 2022 03 5 ;425:127911. Epub 2021 Nov 26. PMID: 34910997
Article Published Date : Jan 04, 2022
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity, Phthalate Toxicity , Thyroid Cancer
Problem Substances : Bisphenol A , Phthalates
[+]

Combined cytotoxicity of polystyrene nanoplastics and phthalate esters on human lung epithelial A549 cells and its mechanism.Apr 14, 2021

Pubmed Data : Ecotoxicol Environ Saf. 2021 Apr 15 ;213:112041. Epub 2021 Feb 15. PMID: 33601174
Article Published Date : Apr 14, 2021
Study Type : In Vitro Study
Additional Links
Diseases : Inflammation, Microplastic Toxicity, Oxidative Stress, Phthalate Toxicity
Additional Keywords : Synergistic Toxicity
Problem Substances : Phthalates, Polystyrene nanoparticles
[+]

Combined exposure to di(2-ethylhexyl) phthalate and polystyrene microplastics induced renal autophagy.Dec 31, 2022

Pubmed Data : Food Chem Toxicol. 2023 Jan ;171:113521. Epub 2022 Nov 21. PMID: 36423728
Article Published Date : Dec 31, 2022
Study Type : In Vitro Study
Additional Links
Diseases : Microplastic Toxicity, Phthalate Toxicity
Additional Keywords : Synergistic Toxicity
Problem Substances : Phthalates
[+]

Cotton and fashion masks increase human exposure to microplastics and phthalates both indoors and outdoors.Jan 16, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxics. 2023 Jan 17 ;11(2). Epub 2023 Jan 17. PMID: 36850963
Article Published Date : Jan 16, 2023
Study Type : In Vitro Study
Additional Links
Diseases : Phthalate Toxicity
Additional Keywords : Microplastic
Problem Substances : Phthalates
[+]

Curcumin may be a potential treatment for preventing the harmful effects of phthalates.Aug 14, 2017

Pubmed Data : Toxicol Appl Pharmacol. 2017 Aug 15 ;329:158-164. PMID: 28595985
Article Published Date : Aug 14, 2017
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Phthalate Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Phthalates
[+]

DEHP (di(2-ethylhexyl)phthalate) stimulates skin pigmentation by perturbing cytoskeletal homeostasis.Jun 30, 2024

Pubmed Data : Toxicol Res. 2024 Jul ;40(3):487-497. Epub 2024 May 22. PMID: 38911535
Article Published Date : Jun 30, 2024
Study Type : In Vitro Study
Additional Links
Diseases : Oxidative Stress, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Di(2-ethylexyl) phthalate and chromosomal damage: Insight on aneugenicity from the cytochalasin-block micronucleus assay.Dec 31, 2023

Pubmed Data : Mutat Res Genet Toxicol Environ Mutagen. 2024 ;898:503791. Epub 2024 Jun 29. PMID: 39147443
Article Published Date : Dec 31, 2023
Study Type : In Vitro Study
Additional Links
Diseases : DNA damage, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Diethylhexyl phthalate can increase proliferation while decrease chemosensitivity of esophageal squamous cell carcinoma cells.Mar 14, 2021

Pubmed Data : Hum Cell. 2021 Mar 15. Epub 2021 Mar 15. PMID: 33721218
Article Published Date : Mar 14, 2021
Study Type : In Vitro Study
Additional Links
Diseases : Esophageal Cancer, Phthalate Toxicity
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

Dimethyl phthalate exposure induces cognitive impairment via COX2-mediated neuroinflammation.Sep 11, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2024 Sep 12 ;284:117039. Epub 2024 Sep 12. PMID: 39270417
Article Published Date : Sep 11, 2024
Study Type : In Vitro Study
Additional Links
Diseases : Brain Inflammation , Cognitive Decline/Dysfunction, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Emerging science indicates that deleterious immunologic changes, including increased propensity to develop wheeze, allergy, and asthma after dietary and inhalation exposure to these chemicals.Sep 03, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Curr Environ Health Rep. 2015 Sep 4. Epub 2015 Sep 4. PMID: 26337065
Article Published Date : Sep 03, 2015
Study Type : Review
Additional Links
Diseases : Allergies, Asthma, Bisphenol-A Toxicity, Phthalate Toxicity
Problem Substances : Bisphenol A , Phthalates
[+]

Estimation of exposure to phthalate esters from consumption of powdered infant formula sampled in Turkey.May 31, 2023

Pubmed Data : Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2023 Jun ;40(6):745-756. Epub 2023 May 22. PMID: 37216587
Article Published Date : May 31, 2023
Study Type : In Vitro Study
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Infant Formula, Phthalates
[+]

Even at a very low concentration phthalates was capable of inducing proliferative effects on breast cancer cells.Nov 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Taiwan J Obstet Gynecol. 2016 Dec ;55(6):826-834. PMID: 28040128
Article Published Date : Nov 30, 2016
Study Type : In Vitro Study
Additional Links
Diseases : Breast Cancer, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Exploring the relationships between exposure levels of bisphenols and phthalates and prostate cancer occurrence.May 24, 2024

Pubmed Data : J Hazard Mater. 2024 May 25 ;474:134736. Epub 2024 May 25. PMID: 38815394
Article Published Date : May 24, 2024
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity, Phthalate Toxicity , Prostate Cancer
Additional Keywords : Increased Risk
Problem Substances : Bisphenol A , Phthalates
[+]

Exposure to phthalates from personal care products: Urinary levels and predictors of exposure.Mar 27, 2022

Pubmed Data : Environ Res. 2022 Mar 28:113194. Epub 2022 Mar 28. PMID: 35358548
Article Published Date : Mar 27, 2022
Study Type : Review
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
[+]

Feminine hygiene products are a neglected source of phthalate exposure in women.Dec 19, 2019

Pubmed Data : Environ Sci Technol. 2019 Dec 20. Epub 2019 Dec 20. PMID: 31859481
Article Published Date : Dec 19, 2019
Study Type : In Vitro Study
Additional Links
Diseases : Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Hericium Erinaceus prevents DEHP-induced mitochondrial dysfunction and apoptosis in PC12 cells.Mar 19, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2020 Mar 20 ;21(6). Epub 2020 Mar 20. PMID: 32244920
Article Published Date : Mar 19, 2020
Study Type : In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Phthalate Toxicity
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents, Nrf2 activation
Problem Substances : Phthalates
[+]

Impact of DEHP exposure on female reproductive health.Mar 31, 2024

Pubmed Data : Environ Toxicol Pharmacol. 2024 Apr ;107:104391. Epub 2024 Feb 16. PMID: 38367918
Article Published Date : Mar 31, 2024
Study Type : Review
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
[+]

Lycopene prevents DEHP-induced hepatic oxidative stress damage by crosstalk between AHR-Nrf2 pathway.Sep 14, 2021

Pubmed Data : Environ Pollut. 2021 Sep 15 ;285:117080. Epub 2021 Apr 7. PMID: 33965855
Article Published Date : Sep 14, 2021
Study Type : In Vitro Study
Additional Links
Substances : Lycopene
Diseases : Oxidative Stress, Phthalate Toxicity
Pharmacological Actions : Antioxidants
Problem Substances : Phthalates
[+]

Mechanisms of testicular disruption from exposure to bisphenol A and phtalates.Feb 07, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Med. 2020 Feb 8 ;9(2). Epub 2020 Feb 8. PMID: 32046352
Article Published Date : Feb 07, 2020
Study Type : Review
Additional Links
Diseases : Bisphenol Toxicity, Phthalate Toxicity , Testicular Injury: Chemical/Metal Induced
Problem Substances : Bisphenol A , Phthalates
[+]

Microplastics and phthalate esters release from teabags into tea drink.Sep 30, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Sci Pollut Res Int. 2023 Oct ;30(47):104209-104222. Epub 2023 Sep 12. PMID: 37697202
Article Published Date : Sep 30, 2023
Study Type : In Vitro Study
Additional Links
Substances : Black Tea, Green Tea
Diseases : Microplastic Toxicity, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Migration of phthalates from PET water bottle in events of repeated uses and associated risk assessment.Jul 07, 2020

Pubmed Data : Environ Sci Pollut Res Int. 2020 Jul 8. Epub 2020 Jul 8. PMID: 32642892
Article Published Date : Jul 07, 2020
Study Type : In Vitro Study
Additional Links
Diseases : Phthalate Toxicity
Additional Keywords : Bottled Water, Plastic Bottle
Problem Substances : Phthalates
[+]

Mixtures of phthalates disrupt expression of genes related to lipid metabolism and peroxisome proliferator-activated receptor signaling.Aug 15, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxicol Sci. 2024 Aug 16. Epub 2024 Aug 16. PMID: 39150890
Article Published Date : Aug 15, 2024
Study Type : In Vitro Study
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
[+]

Myricetin alleviates the mechanism of IL-1β production caused by the endocrine-disrupting chemical Di(2-ethylhexyl) phthalate in RAW 264.7 cells.Dec 12, 2024

Pubmed Data : Tissue Cell. 2024 Dec 13 ;93:102683. Epub 2024 Dec 13. PMID: 39675255
Article Published Date : Dec 12, 2024
Study Type : In Vitro Study
Additional Links
Substances : Myricetin
Diseases : Inflammation, Phthalate Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, NF-kappaB Inhibitor
Problem Substances : Phthalates
[+]

Occurrence of phthalate esters in over-the-counter medicines from China and its implications for human exposure.Nov 02, 2016

Pubmed Data : Environ Int. 2016 Nov 3. Epub 2016 Aug 3. PMID: 27817868
Article Published Date : Nov 02, 2016
Study Type : In Vitro Study
Additional Links
Diseases : Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Phthalate esters and their potential risk in PET bottled water stored under common conditions.Jan 23, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2019 12 24 ;17(1). Epub 2019 Dec 24. PMID: 31878152
Article Published Date : Jan 23, 2019
Study Type : In Vitro Study
Additional Links
Diseases : Phthalate Toxicity
Additional Keywords : Bottled Water, Plastic Bottle
Problem Substances : Phthalates
[+]

Phthalate exposure from several pharmaceutical products exceeded the regulatory exposure limit introduced in 2014.Mar 28, 2017

Pubmed Data : Basic Clin Pharmacol Toxicol. 2017 Mar 29. Epub 2017 Mar 29. PMID: 28371296
Article Published Date : Mar 28, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Phthalate Toxicity
Additional Keywords : Pharmaceutical Contaminants
Problem Substances : Phthalates
[+]

Phthalate migration potential in vacuum-packed fish.Jul 31, 2024

Pubmed Data : Environ Sci Pollut Res Int. 2024 Aug ;31(38):50942-50951. Epub 2024 Aug 6. PMID: 39107639
Article Published Date : Jul 31, 2024
Study Type : In Vitro Study
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
[+]

Phthalate plasticizer di(2-ethyl-hexyl) phthalate induces cyclooxygenase-2 expression in gastric adenocarcinoma cells.Jul 15, 2019

Pubmed Data : Environ Toxicol. 2019 Jul 16. Epub 2019 Jul 16. PMID: 31313480
Article Published Date : Jul 15, 2019
Study Type : In Vitro Study
Additional Links
Diseases : Gastric Cancer, Inflammation, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

Phthalate-induced fetal leydig cell dysfunction mediates male reproductive tract anomalies.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2019 ;10:1309. Epub 2019 Nov 6. PMID: 31780936
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Diseases : Male Reproductive Development Abnormalities, Phthalate Toxicity , Prenatal Chemical Exposures
Problem Substances : Phthalates
[+]

Phthalates induced neurotoxicity: A mechanistic approach. Dec 02, 2024

Pubmed Data : Cent Nerv Syst Agents Med Chem. 2024 Dec 3. Epub 2024 Dec 3. PMID: 39629581
Article Published Date : Dec 02, 2024
Study Type : Review
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
Adverse Pharmacological Actions : Neurotoxic
[+]

Prenatal exposure to dibutyl phthalate and its negative health effects on offspring.Dec 18, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Xenobiot. 2024 Dec 19 ;14(4):2039-2075. Epub 2024 Dec 19. PMID: 39728417
Article Published Date : Dec 18, 2024
Study Type : Review
Additional Links
Diseases : Phthalate Toxicity , Prenatal Chemical Exposures
Problem Substances : Phthalates
[+]

Promising hepatoprotective effects of lycopene in different liver diseases.Nov 30, 2022

Pubmed Data : Life Sci. 2022 Dec 1 ;310:121131. Epub 2022 Oct 25. PMID: 36306869
Article Published Date : Nov 30, 2022
Study Type : Review
Additional Links
Substances : Carotenoids, Lycopene
Diseases : Alcoholic Liver Disease, Liver Cancer, Liver Fibrosis, Liver Injury: Ischemia/reperfusion , Nonalcoholic fatty liver disease (NAFLD), Phthalate Toxicity
Pharmacological Actions : Antioxidants, Hepatoprotective
Problem Substances : Aflatoxin, Bisphenol A , Heavy Metals, Phthalates
[+]

Protective effects of polyphenols against endocrine disrupting chemicals.Jun 30, 2022

Pubmed Data : Food Sci Biotechnol. 2022 Jul ;31(8):905-934. Epub 2022 Jul 12. PMID: 35873371
Article Published Date : Jun 30, 2022
Study Type : Review
Additional Links
Substances : Polyphenols
Diseases : Bisphenol Toxicity, Phthalate Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Problem Substances : Bisphenol A , Endocrine Disrupting Chemicals (EDCs), Phthalates
[+]

Quercetin ameliorates Di (2-ethylhexyl) phthalate-induced nephrotoxicity.Mar 31, 2022

Pubmed Data : Toxicol Res (Camb). 2022 Apr ;11(2):272-285. Epub 2022 Mar 3. PMID: 35510228
Article Published Date : Mar 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Quercetin
Diseases : Kidney Damage: Chemically-Induced, Phthalate Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Heme oxygenase-1 up-regulation, NF-kappaB Inhibitor, Nrf2 activation
Problem Substances : Phthalates
[+]

Reproductive toxic potential of phthalate compounds - State of art review Mar 03, 2021

Pubmed Data : Pharmacol Res. 2021 Mar 4 ;167:105536. Epub 2021 Mar 4. PMID: 33677105
Article Published Date : Mar 03, 2021
Study Type : Review
Additional Links
Diseases : Infertility: Female, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Resveratrol reliefs DEHP-induced defects during human decidualization.Jun 14, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2023 Jun 15 ;258:114931. Epub 2023 Apr 28. PMID: 37121080
Article Published Date : Jun 14, 2023
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
[+]

These endocrine disrupting chemicals interfere with different cell signalling pathways involved in weight and glucose homeostasis.Nov 06, 2016

Pubmed Data : Endocrine. 2016 Nov 7. Epub 2016 Aug 7. PMID: 27822670
Article Published Date : Nov 06, 2016
Study Type : Review
Additional Links
Diseases : Bisphenol Toxicity, Diabetes Mellitus: Type 2, Obesity, Phthalate Toxicity
Problem Substances : Bisphenol A , Phthalates
Adverse Pharmacological Actions : Diabetogenic, Obesogenic
[+]

These results support that some phthalates may be associated with higher odds of preterm birth in humans.Jul 23, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Int. 2019 Jul 24 ;130:104580. Epub 2019 Jul 24. PMID: 31351310
Article Published Date : Jul 23, 2019
Study Type : Review
Additional Links
Diseases : Phthalate Toxicity , Premature Birth
Additional Keywords : Risk Factors
Problem Substances : Phthalates
[+]

This study demonstrates for the first time the possible contribution of PAEs in perfumes to DNA damage.Sep 30, 2017

Pubmed Data : Environ Sci Pollut Res Int. 2017 Oct ;24(30):23903-23914. Epub 2017 Sep 5. PMID: 28875446
Article Published Date : Sep 30, 2017
Study Type : In Vitro Study
Additional Links
Diseases : DNA damage, Phthalate Toxicity
Additional Keywords : Risk Factors
Problem Substances : Perfume: Synthetic, Phthalates
Adverse Pharmacological Actions : Genotoxic
[+]

This study demonstrates that culinary treatment and gastrointestinal digestion promote release and solubilization of additives from plastics ingested with the diet.Jun 03, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Chem. 2024 Jun 4 ;456:139947. Epub 2024 Jun 4. PMID: 38850610
Article Published Date : Jun 03, 2024
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity, Microplastic Toxicity, Phthalate Toxicity
Problem Substances : Bisphenol A , Nano Plastic-and Micro-Particles, Phthalates
[+]

Toxic effects of dibutyl phthalate on trophoblast through mitochondria mediated cellular dysfunction.Dec 05, 2024

Pubmed Data : Toxicol Appl Pharmacol. 2024 Dec 6 ;495:117186. Epub 2024 Dec 6. PMID: 39647510
Article Published Date : Dec 05, 2024
Study Type : In Vitro Study
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
[+]

Wearing face masks as a potential source for inhalation and oral uptake of inanimate toxins.Apr 14, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2024 Apr 15 ;275:115858. Epub 2024 Mar 26. PMID: 38537476
Article Published Date : Apr 14, 2024
Study Type : Review
Additional Links
Diseases : Phthalate Toxicity
Problem Substances : Phthalates
[+]

When the concentration of phthalates reaches a certain level in the body, it can reduce the count and motility of sperm.Dec 31, 2023

Pubmed Data : Zhonghua Nan Ke Xue. 2024 Jan ;30(1):66-71. PMID: 39046416
Article Published Date : Dec 31, 2023
Study Type : Review
Additional Links
Diseases : Infertility: Male, Phthalate Toxicity
Problem Substances : Phthalates
[+]

Worldwide bottled water occurrence of emerging contaminants.Jan 14, 2020

Pubmed Data : J Hazard Mater. 2020 06 15 ;392:122271. Epub 2020 Feb 14. PMID: 32311916
Article Published Date : Jan 14, 2020
Study Type : Review
Additional Links
Diseases : Bisphenol Toxicity, Phthalate Toxicity
Additional Keywords : Bottled Water, Microplastic, Plastic Bottle
Problem Substances : Bisphenol A , Phthalates

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