Osteoarthritis: Knee

Name	AC	CK
Frankincense	14	122
Ginger	13	112
Curcumin	12	86
Turmeric	9	81
Glucosamine	5	41
Sesame Seeds	3	30
Hyaluronic Acid	3	21
Blueberry	2	20
Bromelain	2	20
Cabbage	2	20
Collagen	2	20
Flavonoids	2	20
Garlic	2	20
Lavender: Essential Oil	2	20
MSM (Methylsulfonylmethane)	2	20
Nigella sativa (aka Black Seed)	2	20
Omega-3 Fatty Acids	2	20
Phyllanthus amarus	2	20
Strawberry	2	20
Vitamin D	2	20
Guava	2	12
Krill	2	12
Pomegranate	2	12
Chondroitin Sulfate	2	11
Green Tea	2	11
Melatonin	2	11
Amla Fruit	1	10
Andrographis	1	10
Arnica	1	10
Avocado	1	10
Beta-Caryophyllene	1	10
Bitter Melon	1	10
Black Pepper	1	10
Black Raspberry	1	10
Broccoli	1	10
Cat's Claw	1	10
Catechin	1	10
Chamomile	1	10
Chicken Combs	1	10
Chicken extract	1	10
Chinese Skullcap	1	10
Cucumber	1	10
Echinacea	1	10
Egg	1	10
Elderberry	1	10
Eleutherococcus senticosus	1	10
Fennel	1	10
Guduchi	1	10
Haritaki (Terminalia chebula)	1	10
Hemp Seed	1	10
Homeopathic Medicine: All	1	10
Honey	1	10
Isothiocyanates	1	10
Lactobacillus casei: Shirota	1	10
Magnesium	1	10
Milk Thistle	1	10
Mineral Water	1	10
Mussel: Green-lipped (Perna canaliculus)	1	10
Orange	1	10
Panax Notoginseng	1	10
Passion fruit	1	10
Pomegranate Peel	1	10
Pycnogenol (Pine Bark)	1	10
Red Marine Algae	1	10
Rehmannia	1	10
Rosemaric Acid	1	10
Rosemary	1	10
Seaweed	1	10
Sesame Seed Oil	1	10
Sesame oil: topical	1	10
Soy	1	10
St. Johns Wort	1	10
Tamarind	1	10
Thai Herbal Formulations	1	10
Unsaponifiables	1	10
Vitamin K	1	10
acetyl-11-keto-beta-boswellic acid	1	10
Grape	1	5
Salvia miltiorrhiza	2	4
Chrysin	2	3
Icariin	2	3
6-Shogaol	1	2
Apple Polyphenols	1	2
Celastrol	1	2
Cissus quadrangularis	1	2
Citrus naringin	1	2
Emodin	1	2
Gastrodin	1	2
Genistein	1	2
Glycosaminoglycans	1	2
Grape Seed Extract	1	2
Lactobacillus plantarum	1	2
Lion's Mane (Hericium Erinaceus)	1	2
Mulberry	1	2
Naringenin	1	2
Parthenolide	1	2
Safflower	1	2
Selenium	1	2
Theanine	1	2
Urolithin A	1	2
Vitamin E	1	2
Wogonin	1	2
Fish Oil	1	1
Paeoniflorin	1	1
Stigmasterol	1	1

Name	AC	CK
Diclofenac	3	30
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)	3	30
Sodium Fluoride	2	20
Celecoxib	1	10
Hypnotic Drugs	1	10
Ibuprofen	1	10
Statin Drugs	1	10

Name	AC	CK
Photobiomodulation	50	456
Acupuncture	9	112
Mud therapy	10	102
Tai Chi	8	91
Electroacupuncture	14	85
Laser Treatment	8	83
Massage/Therapeutic Touch	6	55
Spa Bathing	6	52
Acupressure	5	50
Exercise	8	46
Balneotherapy	4	41
Ozone Therapy	3	40
Pulsed EMF field (PEMF)	4	40
Aromatherapy Massage	3	30
Hydrotherapy	3	21
Aromatherapy	2	20
Exercise: Aerobic	2	20
Integrative Medicine	2	20
Prolotherapy	2	20
Cupping	2	11
Acupressure: Auricular	1	10
Ai-Chi Aquatic Exercise	1	10
Bath: Sulfur	1	10
Dietary Modification: Mediterranean Diet	1	10
Homeopathic Treatment	1	10
Infrared Light	1	10
Magnet Therapy	1	10
Moxibustion	1	10
Qigong	1	10
Reiki Therapy	1	10
Transcutaneous electrical nerve stimulation (TENS)	1	10
Ultrasound therapy	1	10
Yoga	1	10
Dietary Modification: Low Carbohydrate/Ketogenic	1	2
Whole-Body Vibration	1	2

[+]

Acupuncture has beneficial effect on pain relief and improves function activities in patients with Knee osteoarthritis.Dec 31, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Am J Chin Med. 2017 Jun 28:1-21. Epub 2017 Jun 28. PMID: 28659033

Article Published Date : Jun 27, 2017

Study Type : Meta Analysis

Additional Links

Diseases : Osteoarthritis: Knee

Therapeutic Actions : Electroacupuncture

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Rep. 2020 Jul 3 ;10(1):11004. Epub 2020 Jul 3. PMID: 32620866

Article Published Date : Jul 02, 2020

Study Type : Human Study

Additional Links

Diseases : Osteoarthritis: Knee

Therapeutic Actions : Spa Bathing

[+]

A 12-week garlic supplementation had beneficial effects on symptom relief in overweight or obese women with knee osteoarthritis.May 31, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Clin Pract. 2018 Jun ;72(6):e13208. Epub 2018 May 23. PMID: 29790635

Article Published Date : May 31, 2018

Study Type : Human Study

Additional Links

Substances : Garlic

Diseases : Obesity, Osteoarthritis: Knee

Additional Keywords : Plant Extracts

[+]

A 6-week course of moxibustion seems to relieve pain effectively and improve function in patients with KOA for up to 18 weeks after the end of treatment.Dec 31, 2013

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Arthritis Res Ther. 2014 ;16(3):R133. Epub 2014 Jun 24. PMID: 24962039

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mol Med Rep. 2013 Nov ;8(5):1542-8. Epub 2013 Aug 29. PMID: 24002213

Article Published Date : Oct 31, 2013

Study Type : Human Study

Additional Links

Substances : Frankincense, Turmeric

Diseases : Osteoarthritis: Knee

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors

Additional Keywords : Plant Extracts, Superiority of Natural Substances versus Drugs

Problem Substances : Celecoxib, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

[+]

A herbal formulation is a safe and effective intervention for management of joint discomfort.Apr 30, 2018

Click here to read the entire abstract

Pubmed Data : J Med Food. 2018 May ;21(5):511-520. Epub 2018 Apr 30. PMID: 29708818

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Jpn J Nurs Sci. 2019 May 30. Epub 2019 May 30. PMID: 31144450

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : QJM. 2021 Aug 31. Epub 2021 Aug 31. PMID: 34463759

Article Published Date : Aug 30, 2021

Study Type : Human Study

Additional Links

Diseases : Osteoarthritis: Knee

Therapeutic Actions : Acupressure: Auricular

Pharmacological Actions : Analgesics

Additional Keywords : Medication Reduction

[+]

Avocado/soybean unsaponifiables are safe and effective in the treatment of symptomatic osteoarthritis of the knee and hip.Dec 01, 1997

Click here to read the entire abstract

Pubmed Data : Rev Rhum Engl Ed. 1997 Dec;64(12):825-34. PMID: 9476272

Article Published Date : Dec 01, 1997

Study Type : Human Study

Additional Links

Substances : Avocado, Soy, Unsaponifiables

Diseases : Osteoarthritis, Osteoarthritis: Hip , Osteoarthritis: Knee

Additional Keywords : Drug Sparing, Plant Extracts

[+]

Ayurvedic medicine offers a good alternative to glucosamine and celecoxib in the treatment of symptomatic knee osteoarthritis.Jul 31, 2013

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Rheumatology (Oxford). 2013 Aug ;52(8):1408-17. Epub 2013 Jan 30. PMID: 23365148

Article Published Date : Jul 31, 2013

Article Published Date : Dec 31, 2002

Study Type : Human Study

Additional Links

Substances : Frankincense

Diseases : Arthritis, Osteoarthritis: Knee

Pharmacological Actions : Analgesics, Anti-Inflammatory Agents

Additional Keywords : Phytotherapy, Plant Extracts

Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

[+]

Both electroacupuncture and manual acupuncture interventions in knee osteoarthritis were feasible and appeared safe.Feb 04, 2020

Click here to read the entire abstract

Pubmed Data : Acupunct Med. 2020 Feb 5:964528419900781. Epub 2020 Feb 5. PMID: 32022581

Article Published Date : Feb 04, 2020

Study Type : Human Study

Additional Links

Diseases : Osteoarthritis: Knee

Therapeutic Actions : Acupuncture, Electroacupuncture

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Int Soc Sports Nutr. 2023 Dec ;20(1):2243252. PMID: 37551682

Article Published Date : Nov 30, 2023

Study Type : Human Study

Additional Links

Substances : Collagen

Diseases : Osteoarthritis: Knee

Therapeutic Actions : Exercise

[+]

Constitutes of Boswellia serrata extract act synergistically to exert anti-inflammatory/anti-arthritic activity.Mar 05, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Phytother Res. 2019 Mar 6. Epub 2019 Mar 6. PMID: 30838706

Article Published Date : Mar 05, 2019

Study Type : Human Study

Additional Links

Substances : acetyl-11-keto-beta-boswellic acid, Frankincense

Diseases : Osteoarthritis: Knee

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Natural Substance Synergy

[+]

Continuous intake of guava leaf extract might relieve knee pain.Apr 22, 2018

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Pubmed Data : Aging Clin Exp Res. 2018 Apr 23. Epub 2018 Apr 23. PMID: 29687303

Article Published Date : Apr 22, 2018

Study Type : Human Study

Additional Links

Diseases : Osteoarthritis: Knee

Pharmacological Actions : Analgesics

[+]

Click here to read the entire abstract

Pubmed Data : Bioelectromagnetics. 2015 Dec ;36(8):576-85. Epub 2015 Nov 12. PMID: 26562074

Article Published Date : Nov 30, 2015

Study Type : Human Study

Additional Links

Diseases : Osteoarthritis: Knee

Therapeutic Actions : Pulsed EMF field (PEMF)

Pharmacological Actions : Analgesics

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[+]

Pubmed Data : Lasers Med Sci. 2017 Apr ;32(3):503-511. Epub 2017 Jan 11. PMID: 28078503

Article Published Date : Mar 31, 2017

Study Type : Human Study

Additional Links

Substances : Chondroitin Sulfate, Glucosamine

Diseases : Osteoarthritis: Knee

Therapeutic Actions : Photobiomodulation

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Eggshell membrane significantly reduced both joint pain and stiffness in patients with osteoarthritis of the knee. Aug 01, 2009

Click here to read the entire abstract

Pubmed Data : Clin Rheumatol. 2009 Aug;28(8):907-14. Epub 2009 Apr 2. PMID: 19340512

Article Published Date : Aug 01, 2009

Study Type : Human Study

Additional Links

Substances : Egg

Diseases : Osteoarthritis, Osteoarthritis: Knee

[+]

Electroacupuncture ameliorates knee osteoarthritis.Aug 11, 2024

Click here to read the entire abstract

Pubmed Data : Clin Nutr. 2016 Dec 18. Epub 2016 Dec 18. PMID: 28038881

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2020 Aug ;34(8):2067-2073. Epub 2020 Mar 16. PMID: 32180294

Article Published Date : Jul 31, 2020

Study Type : Human Study

Additional Links

Substances : Black Pepper, Ginger, Turmeric

Diseases : Osteoarthritis: Knee

Pharmacological Actions : Anti-Inflammatory Agents, Postaglandin PGE2 downregulation

Additional Keywords : Natural Substances Versus Drugs

[+]

High-intensity versus low-level laser therapy in the treatment of patients with knee osteoarthritis.Jun 30, 2014

Click here to read the entire abstract

Pubmed Data : Lasers Med Sci. 2014 Jul ;29(4):1371-6. Epub 2014 Feb 1. PMID: 24487957

Article Published Date : Jun 30, 2014

Study Type : Human Study

Additional Links

Diseases : Osteoarthritis: Knee

Therapeutic Actions : Exercise, Laser Treatment , Photobiomodulation

[+]

High-rosmarinic acid spearmint tea in the management of knee osteoarthritis symptoms.Nov 30, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Med Food. 2014 Dec ;17(12):1361-7. PMID: 25058311

Article Published Date : Nov 30, 2014

Click here to read the entire abstract

Pubmed Data : J Bone Joint Surg Am. 2003 Jul;85-A(7):1197-203. PMID: 12851342

Article Published Date : Jul 01, 2003

Study Type : Human Study

Additional Links

Substances : Hyaluronic Acid

Diseases : Osteoarthritis: Knee

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Cortisone Alternatives, Natural Substances Versus Drugs

[+]

[+]

Lactobacillus casei Shirota consumption could serve as a novel therapeutic option in the clinical management of knee osteoarthritis.Oct 12, 2017

Click here to read the entire abstract

Pubmed Data : Benef Microbes. 2017 Oct 13 ;8(5):697-703. Epub 2017 Jul 20. PMID: 28726510

Article Published Date : Oct 12, 2017

Study Type : Human Study

Additional Links

Substances : Lactobacillus casei: Shirota

Diseases : C-Reactive Protein, Osteoarthritis: Knee

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Laser acupuncture in knee osteoarthritis.Jan 31, 2007

Click here to read the entire abstract

Pubmed Data : Photomed Laser Surg. 2007 Feb ;25(1):14-20. PMID: 17352632

Article Published Date : Jan 31, 2007

Study Type : Human Study

Additional Links

Diseases : Osteoarthritis: Knee

Therapeutic Actions : Acupuncture, Laser Treatment

[+]

Laser therapy versus pulsed electromagnetic field therapy as treatment modalities for early knee osteoarthritis.Mar 15, 2023

Pubmed Data : Arthritis Rheum. 2006 Apr;54(4):1255-61. PMID: 16572460

Article Published Date : Apr 01, 2006

Study Type : Human Study

Additional Links

Substances : Vitamin K

Diseases : Bone Spur, Osteoarthritis, Osteoarthritis: Knee, Osteophyte

[+]

low-level laser therapy may be considered as a feasible option in treating elderly patients with knee osteoarthritis.Dec 31, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Immunopathol Pharmacol. 2016 Mar ;29(1):140-6. Epub 2015 Dec 18. PMID: 26684635

Article Published Date : Feb 29, 2016

Study Type : Human Study

Additional Links

Substances : Frankincense, MSM (Methylsulfonylmethane)

Diseases : Osteoarthritis: Knee

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors

[+]

Methylsulfonylmethane improves knee quality of life in participants with mild knee pain.Jun 29, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Rheumatol Int. 2013 Oct ;33(10):2569-76. Epub 2013 May 21. PMID: 23689969

Article Published Date : Sep 30, 2013

Study Type : Human Study

Additional Links

Diseases : Osteoarthritis: Knee

Therapeutic Actions : Mud therapy

[+]

[+]

Self-administered acupressure and exercise for patients with osteoarthritis.Feb 28, 2022

Click here to read the entire abstract

Pubmed Data : Clin Rehabil. 2022 Mar ;36(3):350-358. Epub 2021 Oct 18. PMID: 34658285

Article Published Date : Feb 28, 2022

Study Type : Human Study

Additional Links

Diseases : Osteoarthritis: Knee

Therapeutic Actions : Acupressure

[+]

Self-administered acupressure for probable knee osteoarthritis in middle-aged and older adults.Mar 31, 2024

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : JAMA Netw Open. 2024 Apr 1 ;7(4):e245830. Epub 2024 Apr 1. PMID: 38639940

Article Published Date : Mar 31, 2024

Study Type : Human Study

Additional Links

Diseases : Osteoarthritis: Knee

Therapeutic Actions : Acupressure

Pharmacological Actions : Analgesics

[+]

Self-administered acupressure is superior to usual care in pain and physical function improvement for older people with knee osteoarthritis.Apr 23, 2017

Click here to read the entire abstract

Pubmed Data : Arthritis Care Res (Hoboken). 2017 Apr 24. Epub 2017 Apr 24. PMID: 28437570

Article Published Date : Apr 23, 2017

Study Type : Human Study

Additional Links

Diseases : Osteoarthritis: Knee

Therapeutic Actions : Acupressure

[+]

Self-knee massage with ginger oil in patients with osteoarthritis.Oct 31, 2017

Click here to read the entire abstract

Pubmed Data : Res Theory Nurs Pract. 2017 Nov 1 ;31(4):379-392. PMID: 29137696

Article Published Date : Oct 31, 2017

Study Type : Human Study

Additional Links

Substances : Ginger

Diseases : Osteoarthritis: Knee

Therapeutic Actions : Massage/Therapeutic Touch

Pharmacological Actions : Analgesics

Additional Keywords : Plant Oils

[+]

Sesame seed is a natural and safe substance that may have beneficial effects in patients with knee osteoarthritis.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Arthritis Rheum. 2009 Nov 15;61(11):1545-53. PMID: 19877092

Article Published Date : Nov 15, 2009

Study Type : Human Study

Additional Links

Diseases : Osteoarthritis, Osteoarthritis: Knee

Therapeutic Actions : Tai Chi

[+]

Tamarindus indica seed extract-based botanical compositions alleviate knee pain and improve joint function in mild-to-moderate osteoarthritis.Dec 31, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Evid Based Complement Alternat Med. 2022 ;2022:2226139. Epub 2022 Jan 19. PMID: 35096104

Article Published Date : Dec 31, 2021

Study Type : Human Study

Additional Links

Substances : Tamarind

Diseases : Osteoarthritis: Knee

Pharmacological Actions : Osteoprotective

[+]

Thai massage and thai herbal compression provided comparable clinical efficacy to oral ibuprofen after three weeks of treatment.Dec 31, 2013

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Res Int. 2014 ;2014:490512. Epub 2014 Sep 1. PMID: 25254207

Article Published Date : Dec 31, 2013

Study Type : Human Study

Additional Links

Substances : Thai Herbal Formulations

Diseases : Osteoarthritis: Knee

Therapeutic Actions : Acupressure, Massage/Therapeutic Touch

Pharmacological Actions : Analgesics, Anti-Inflammatory Agents

Additional Keywords : Natural Substances Versus Drugs

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutr J. 2023 Mar 15 ;22(1):17. Epub 2023 Mar 15. PMID: 36918892

Click here to read the entire abstract

Pubmed Data : Arch Phys Med Rehabil. 2024 Mar ;105(3):593-603. Epub 2023 Jul 5. PMID: 37419235

Article Published Date : Feb 29, 2024

Study Type : Human Study

Additional Links

Diseases : Osteoarthritis: Knee

Therapeutic Actions : Photobiomodulation

Pharmacological Actions : Analgesics

[+]

The findings support the potential efficacy of curcumin for the treatment of osteoarthritis of the knee.Dec 22, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

[+]

These results suggest that PEMF therapy is effective for pain management in knee osteoarthritis patients.Mar 31, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Rheumatology (Oxford). 2016 Apr ;55(4):755-62. Epub 2015 Dec 24. PMID: 26705327

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Electron Physician. 2016 Nov ;8(11):3193-3197. Epub 2016 Nov 25. PMID: 28344755

Article Published Date : Oct 31, 2016

Study Type : Human Study

Additional Links

Substances : Nigella sativa (aka Black Seed)

Diseases : Osteoarthritis: Knee

Pharmacological Actions : Analgesics

[+]

Topical sesame oil was non-inferior to diclofenac gel on the reduction of the knee osteoarthritis pain.Nov 30, 2019

Click here to read the entire abstract

Pubmed Data : Complement Ther Med. 2019 Dec ;47:102183. Epub 2019 Aug 22. PMID: 31780006

Article Published Date : Nov 30, 2019

Study Type : Human Study

Additional Links

Substances : Sesame oil: topical, Sesame Seed Oil

Diseases : Osteoarthritis: Knee

Pharmacological Actions : Analgesics

Additional Keywords : Natural Substances Versus Drugs

Problem Substances : Diclofenac

[+]

Treatment with LLLT improves pain and function over the short term in patients with knee osteoarthritis.Dec 31, 2010

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Rev Bras Ortop. 2011 ;46(5):526-33. Epub 2015 Dec 6. PMID: 27027049

Article Published Date : Dec 31, 2010

Study Type : Human Study

Additional Links

Diseases : Osteoarthritis: Knee

Therapeutic Actions : Photobiomodulation

Pharmacological Actions : Analgesics

[+]

Turmeric extract appears to be as safe and effective as ibuprofen for the treatment of knee osteoarthritis. May 01, 2010

Click here to read the entire abstract

Pubmed Data : Int J Mol Med. 2010 May;25(5):729-34. PMID: 19678780

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Med Food. 2014 Apr ;17(4):479-86. PMID: 24720858

Article Published Date : Mar 31, 2014

Study Type : Animal Study, Human In Vitro

Additional Links

Substances : Grape

Diseases : Arthritis, Osteoarthritis: Knee

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Plant Extracts

[+]

Electroacupuncture for acute pain flare-up of knee osteoarthritis.Dec 31, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Neurol. 2022 ;13:1026441. Epub 2022 Oct 25. PMID: 36388192

Article Published Date : Dec 31, 2021

Study Type : Human: Case Report

Additional Links

Diseases : Osteoarthritis: Knee

Therapeutic Actions : Electroacupuncture

Pharmacological Actions : Analgesics

[+]

6-Shogaol treatment improves experimental knee osteoarthritis.Jun 26, 2022

Click here to read the entire abstract

Pubmed Data : Br J Pharmacol. 2022 Jun 27. Epub 2022 Jun 27. PMID: 35760458

Article Published Date : Jun 26, 2022

Study Type : Animal Study

Additional Links

Substances : 6-Shogaol

Diseases : Osteoarthritis: Knee

Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory

[+]

Pharmacological Actions : Chondroprotective

[+]

Electroacupuncture potentiates cannabinoid receptor-mediated descending inhibitory control in a mouse model of knee osteoarthritis.Dec 31, 2017

Click here to read the entire abstract

Pubmed Data : Front Mol Neurosci. 2018 ;11:112. Epub 2018 Apr 6. PMID: 29681797

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Diseases : Osteoarthritis: Knee

Therapeutic Actions : Electroacupuncture

Pharmacological Actions : Antinoceceptive

Additional Keywords : Cannabinoid Receptors

[+]

Electroacupuncture potentiates peripheral CB2 receptor-inhibited chronic pain in a mouse model of knee osteoarthritis.Dec 31, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Massage therapy seems to be efficacious in the treatment of osteoarthritis of the knee. Dec 11, 2006

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Pubmed Data : Arch Intern Med. 2006 Dec 11-25;166(22):2533-8. PMID: 17159021

Article Published Date : Dec 11, 2006

Study Type : Animal Study

Additional Links

Diseases : Osteoarthritis, Osteoarthritis: Knee

Therapeutic Actions : Massage/Therapeutic Touch

[+]

Modulation of gut microbiota by crude mulberry polysaccharide attenuates knee osteoarthritis progression in rats.Feb 29, 2024

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Pubmed Data : Int J Biol Macromol. 2024 Mar ;262(Pt 2):129936. Epub 2024 Feb 1. PMID: 38309391

Article Published Date : Feb 29, 2024

Study Type : Animal Study

Additional Links

Substances : Mulberry

Diseases : Osteoarthritis: Knee

Pharmacological Actions : Anti-Inflammatory Agents, Osteoprotective

Additional Keywords : Polysaccharides

[+]

Musculoskeletal atrophy in an experimental model of knee osteoarthritis: The effects of exercise training and low-level laser therapy.Jul 31, 2015

Click here to read the entire abstract

Pubmed Data : Am J Phys Med Rehabil. 2015 Aug ;94(8):609-16. PMID: 25299541

Article Published Date : Jul 31, 2015

Study Type : Animal Study

Additional Links

Diseases : Osteoarthritis: Knee

Therapeutic Actions : Exercise, Photobiomodulation

[+]

Naringenin could be a potent therapeutic option for the treatment of osteoarthritis.Mar 22, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Braz J Med Biol Res. 2017 Mar 23 ;50(4):e5714. Epub 2017 Mar 23. PMID: 28355351

Article Published Date : Mar 22, 2017

Study Type : Animal Study

Additional Links

Substances : Naringenin

Diseases : Osteoarthritis: Knee

Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, NF-kappaB Inhibitor

[+]

Naringin and bone marrow mesenchymal stem cells repair articular cartilage defects.Oct 31, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Exp Ther Med. 2020 Nov ;20(5):59. Epub 2020 Sep 4. PMID: 32952649

Article Published Date : Oct 31, 2020

Study Type : Animal Study

Additional Links

Substances : Citrus naringin

Diseases : Osteoarthritis: Knee

Pharmacological Actions : Osteoprotective

Additional Keywords : Bone Regeneration

[+]

Parthenolide could down-regulate the blood IL-1beta and TNF-alpha concentrations in model of knee osteoarthritis. Sep 30, 2013

Click here to read the entire abstract

Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 2013 Oct ;33(10):1382-4. PMID: 24432684

Pubmed Data : Phytother Res. 2009 Jun 5. PMID: 19504467

Article Published Date : Jun 05, 2009

Study Type : Animal Study

Additional Links

Substances : Pomegranate

Diseases : Osteoarthritis, Osteoarthritis: Knee

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Repairing effect and mechanism of hydroxysafflor yellow A and sodium hyaluronate for knee osteoarthritis.Apr 30, 2023

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Altern Ther Health Med. 2023 May ;29(4):146-151. PMID: 36933246

Article Published Date : Apr 30, 2023

Study Type : Animal Study

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Substances : Safflower

Diseases : Inflammation, Osteoarthritis: Knee

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Osteoprotective

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Salvia miltiorrhiza-asarum ointment combined with Chinese medical massage alleviates symptoms of osteoarthritis.Jul 31, 2021

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Pubmed Data : J Tradit Chin Med. 2021 Aug ;41(4):600-607. PMID: 34392653

Pubmed Data : Knee. 2024 Mar ;47:208-218. Epub 2024 Feb 29. PMID: 38422741

Article Published Date : Feb 29, 2024

Study Type : Animal Study

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Diseases : Osteoarthritis: Knee

Therapeutic Actions : Photobiomodulation

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The protective effects of grape seed oil on induced osteoarthritis of the knee in male rat models.Sep 09, 2020

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Additional Keywords : Natural Substance Synergy, Plant Extracts

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Curcumin works synergistically with celecoxib to potentiate a growth-inhibitory and pro-apoptotic in osteoarthritis synovial adherent cells.Feb 01, 2006

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Pubmed Data : Rheumatology (Oxford). 2006 Feb;45(2):171-7. Epub 2005 Oct 25. PMID: 16249246

Article Published Date : Feb 01, 2006

Study Type : In Vitro Study

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Substances : Curcumin

Diseases : Osteoarthritis: Knee, Oxidative Stress

Pharmacological Actions : Antioxidants, Antiproliferative , Apoptotic, Cyclooxygenase 1 Inhibitor, Cyclooxygenase 2 Inhibitors

Additional Keywords : Drug: Celecoxib, Drug Synergy

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Current advances of photobiomodulation therapy in treating knee osteoarthritis.Dec 31, 2022

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Research on electroacupuncture parameters for knee osteoarthritis based on data mining.Aug 30, 2022

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Pubmed Data : Eur J Med Res. 2022 Aug 31 ;27(1):162. Epub 2022 Aug 31. PMID: 36045455

Article Published Date : Aug 30, 2022

Study Type : Review

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Diseases : Osteoarthritis: Knee

Therapeutic Actions : Electroacupuncture

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Stigmasterol alleviates interleukin-1beta-induced chondrocyte injury.Nov 30, 2021

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View the Evidence: 269 Abstracts with Osteoarthritis: Knee Research

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Acupuncture has beneficial effect on pain relief and improves function activities in patients with Knee osteoarthritis.Dec 31, 2021

Effect of low-level laser therapy plus exercise therapy on pain, range of motion, muscle strength, and function in knee osteoarthritis.Feb 28, 2023

Effectiveness of high-intensity laser therapy in the management of patients with knee osteoarthritis.Dec 31, 2019

Effects of Tai chi in knee osteoarthritis patients.Aug 24, 2023

Safety and effectiveness of low-level laser therapy in patients with knee osteoarthritis.Dec 31, 2016

Short-term efficacy of physical interventions in osteoarthritic knee pain.Jun 21, 2007

Systematic review and network meta-analysis of acupuncture combined with massage in treating knee osteoarthritis.Dec 31, 2021

Balneotherapy and spa therapy can significantly improve quality of life of patients with knee osteoarthritis.Sep 30, 2018

Curcuminoids may have some beneficial effects on knee pain and quality of life in patients with knee osteoarthritis.Mar 31, 2017

Electro-acupuncture is a great opportunity to remarkably alleviate the pain and improve the physical function of knee osteoarthritis patients.Jun 27, 2017

Intra-articular infiltrations of ozone can be used as an optional effective treatment for the management of pain related to knee osteoarthritis.Jan 27, 2019

Low level laser therapy appears to have therapeutic value in the treatment of osteoarthritis.Jan 01, 2007

Low-level laser therapy reduces pain and disability in knee osteoarthritis.Oct 27, 2019

Mud therapy can effectively alleviate the pain and improve joint function for knee osteoarthritis.Mar 31, 2020

Mud therapy is a favourable option for pain relief in patients with knee OA.Sep 30, 2013

The results demonstrated the positive effect of laser photobiomodulation for cartilage defects.Dec 16, 2019

Spa therapy with physical rehabilitation is an alternative to usual spa therapy protocol in symptomatic knee osteoarthritis.Jul 02, 2020

A 12-week garlic supplementation had beneficial effects on symptom relief in overweight or obese women with knee osteoarthritis.May 31, 2018

A 6-week course of moxibustion seems to relieve pain effectively and improve function in patients with KOA for up to 18 weeks after the end of treatment.Dec 31, 2013

A combination of baicalin (a compound found within Chinese skullcap) and catechin (a polyphenol plant antioxidant) are as effective as naproxen in treating osteoarthritis of the knee. Dec 01, 1985

A five-week Ai Chi intervention can improve the pain and stiffness of knee osteoarthritis and self-perceived physical functions.Apr 30, 2017

A formulation containing Frankincense and Turmeric extracts demonstrated a greater improvement in the treatment of OA than celecoxib.Oct 31, 2013

A herbal formulation is a safe and effective intervention for management of joint discomfort.Apr 30, 2018

A highly standardised ginger and Echinacea extract could be beneficial for people with knee osteoarthritis.Oct 12, 2016

A homeopathic gel compares favorably to NSAID gel for treating osteoarthritis of the knee.Jul 01, 2000

A randomised controlled trial of laser acupuncture improves early outcomes of osteoarthritis patients' physical functional ability after total knee replacement.Apr 30, 2021

A seaweed derived mineral supplement may increase range of motion and walking distances in subjects with osteoarthritis of the knee and has a drug sparing effect. Feb 02, 2009

A syrup, composed of a combination of honey and ginger could be used for improvement of symptomatic treatment of osteoarthritis.Nov 30, 2022

A two-session self-administered acupressure training was acceptable to and feasible in participants with knee osteoarthritis.Nov 12, 2019

A water soluble extract of Panax notoginseng, Rehmannia glutinosa and Eleutherococcus senticosus is safe and effective for symptomatic improvement of pain and physical function in patients with knee osteoarthritis. Feb 01, 2009

Acupuncture combined with medication has a better effects in the treatment of knee osteoarthritis in the early stage than that of the simple medication.Mar 24, 2019

Acupuncture or electroacupuncture combined with usual care is more effective than usual care alone for the treatment of knee osteoarthritis.Jan 31, 2019

Acupuncture was effective as an alternative or complementary treatment of knee osteoarthritis.Feb 04, 2018

Aerobic training modulates T cell activation in elderly women with knee osteoarthritis.Dec 31, 2015

Aflapin exhibited better efficacy compared to 5-Loxin to reduce pain and improve physical functions significantly in OA subjects.Dec 31, 2009

Analgesic effect of high intensity laser therapy in knee osteoarthritis.Aug 31, 2011

Andrographis extract was found to be effective and safe in reducing pain in individuals suffering from mild to moderate knee osteoarthritis.Apr 09, 2019

Arnica montana gel is safe, well-tolerated and effective in the treatment of mild to moderate osteoarthritis of the kneeSep 01, 2002

Aroma-massage therapy with ginger and orange oil have potential as an alternative method for short-term knee pain relief.May 01, 2006

Aromatherapy massage in patients with osteoarthritis reduced knee pain scores, decreased morning stiffness, and improved physical functioning statusMar 04, 2018

Aromatherapy massage performed in elderly patients with knee osteoarthritis reduced pain and improved functional status and quality of life.May 29, 2019

Aromatherapy massage with lavender essential oil may reduce the incidence of activities of daily living disability in patients with osteoarthritis of the knee.Jan 31, 2018

Aromatherapy massage with lavender essential oil was found effective in relieving pain in patients with knee osteoarthritis.Oct 31, 2016

Auricular acupressure for treating early stage of knee osteoarthritis.Aug 30, 2021

Avocado/soybean unsaponifiables are safe and effective in the treatment of symptomatic osteoarthritis of the knee and hip.Dec 01, 1997

Ayurvedic medicine offers a good alternative to glucosamine and celecoxib in the treatment of symptomatic knee osteoarthritis.Jul 31, 2013

Balneotherapy and mud-pack therapy were effective in treating patients with knee osteoarthritis. Jan 01, 2007

Balneotherapy for knee osteoarthritis in S. Jorge.May 31, 2020

Balneotherapy has positive effects on gait properties and clinical health quality parameters of patients with knee osteoarthritis in short-term evaluations.Jul 09, 2009

Balneotherapy plus physical therapy was more effective than physical therapy alone in KOA patients aged over 65 years. Nov 30, 2019

Bath thermal waters in the treatment of knee osteoarthritis.Jul 31, 2016

Bioavailable turmeric extract is as effective as paracetamol in reducing pain and other symptoms of knee osteoarthritis.Jan 29, 2021

Blueberries may have a positive effect on joint health by reducing pain, stiffness, and difficulty to perform daily activities.May 31, 2019

Blueberries may improve quality of life in individuals with symptomatic knee osteoarthritis.Jan 28, 2019

Boswellia serrata Extract could be recommended in patients of osteoarthritis of the knee with possible therapeutic use in other arthritis.Dec 31, 2002

Both electroacupuncture and manual acupuncture interventions in knee osteoarthritis were feasible and appeared safe.Feb 04, 2020

Bromelain has no difference in reducing symptoms of mild-to-moderate knee OA after 4 weeks when compared with diclofenac.Sep 30, 2016

Bromelain reduces mild acute knee pain and improves well-being in a dose-dependent fashion in an open study of otherwise healthy adults.Dec 01, 2002

Cabbage leaf application and cooling gel pad application showed similar improvements in reducing osteoarthritis symptoms.Dec 31, 2021

Cats claw is an effective treatment for osteoarthritis.Sep 01, 2001

Chamomile oil decreased the analgesic demand of patients with knee osteoarthritis.Jul 31, 2015

Collagen peptides supplementation improves function, pain, and physical and mental outcomes in active adults.Nov 30, 2023

Constitutes of Boswellia serrata extract act synergistically to exert anti-inflammatory/anti-arthritic activity.Mar 05, 2019

Continuous intake of guava leaf extract might relieve knee pain.Apr 22, 2018

Curcuminoids represent an effective and safe alternative treatment for OA.Oct 31, 2014

Customized photobiomodulation modulates pain and alters thermography pattern in patients with knee osteoarthritis.Sep 30, 2022

Dietary strawberries may have significant analgesic and anti-inflammatory effects in obese adults with established knee osteoarthritis.Aug 27, 2017

Double-blind trial of solid lipid Boswellia serrata particles vs. standardized Boswellia serrata gum extract for osteoarthritis of knee. Jun 07, 2020

Effect of dry cupping versus soft and prolonged massage in the management of knee osteoarthritis.Mar 30, 2021

Effect of Electroacupuncture on gut microbiota in participants with knee osteoarthritis.Dec 31, 2020

Effect of mud-bath therapy on serum biomarkers in patients with knee osteoarthritis.Feb 29, 2016

Effectiveness of Cucumis sativus extract versus glucosamine-chondroitin in the management of moderate osteoarthritis.Dec 31, 2017

Osteoarthritis: Knee

View the Evidence:
269 Abstracts with Osteoarthritis: Knee Research