Oral Cancer

Name	AC	CK
Fruit: All	3	60
Curcumin	27	53
Coffee	2	40
Vegetables: All	2	40
Black Raspberry	10	32
Resveratrol	9	24
Apples	1	20
Flavonoids	12	14
Turmeric	3	14
Green Tea	2	11
Vitamin A	2	11
Vitamin E: alpha tocopherol	2	11
Arginine	1	10
Copper	1	10
Licorice	10	10
Omega-3 Fatty Acids	1	10
Tea: Oolong	1	10
Turmeric: Volatile Oils	1	10
Lactoferrin	7	9
Quercetin	8	9
Astaxanthin	4	8
Fucoidan	6	8
Catechin	5	7
Hesperidin	3	7
Honokiol	5	7
Parthenolide	2	7
Bitter Melon	4	6
Fisetin	4	6
Gynostemma	2	6
Isothiocyanates	3	6
Neem	5	6
Thymoquinone	5	6
Vitamin D	5	6
Ashwagandha	4	5
Black Tea	3	5
Bloodroot	1	5
EGCG (Epigallocatechin gallate)	5	5
Ellagic Acid	4	5
Oridonin	4	5
Tanshinone IIA	3	5
Tea	3	5
Anthocyanins	4	4
Blueberry	4	4
Chlorophyllin	2	4
Cinnamon	4	4
Diosmin	2	4
Garlic	3	4
Gingerol	3	4
Piperlongumine	3	4
Polyphenols	4	4
Pomegranate	4	4
Salvia miltiorrhiza	4	4
Aloe Vera	2	3
Apigenin	2	3
Bilberry	1	3
Bisdemethoxycurcumin	2	3
Caffeic acid phenethyl ester	2	3
Cinnamaldehyde	3	3
Curcuminoids	2	3
Curcumol	1	3
Diosgenin	3	3
Emodin	2	3
Gallic Acid	3	3
Ginkgo biloba	3	3
Ginsenosides	2	3
Guduchi	3	3
Hyaluronic Acid	1	3
Magnolia	2	3
Mangosteen	3	3
Manuka Honey	1	3
Melatonin	3	3
Naringenin	3	3
Phloretin	3	3
Piperine	2	3
Sulforaphane	2	3
Toona sinensis	2	3
Tualang Honey	2	3
Verbascoside	2	3
Allicin	2	2
Andrographis	2	2
Artemisinin	2	2
Avocado	2	2
Baicalein	2	2
Bee Propolis	1	2
Betulinic acid	2	2
Capsaicin	2	2
Carotenoids	1	2
Chrysin	2	2
Cocoa	1	2
Cordyceps Militaris	2	2
Cranberry	2	2
Crocin	2	2
Demethoxycurcumin	1	2
Eugenol	2	2
Grapefruit	1	2
Holy Basil	2	2
Icariin	2	2
Lactobacillus plantarum	2	2
Lactobacillus rhamnosus GG	2	2
Liquiritigenin	1	2
Lycopene	2	2
Magnolol	2	2
Mangiferin	1	2
Nobiletin	2	2
Paeonol	1	2
Piperidines	1	2
Polypodium leucotomos	1	2
Probiotics	2	2
Prunella vulgaris	1	2
Pterostilbene	2	2
Raspberry	2	2
Rosemary	1	2
St. Johns Wort	1	2
Strawberry	2	2
Ursolic Acid	2	2
beta-Carotene	1	2
6-Shogaol	1	1
Adlay	1	1
Amygdalin (laetrile)	1	1
Andrographolide	1	1
Apple Polyphenols	1	1
Bacopa	1	1
Banana	1	1
Benzyl isothiocyanate	1	1
Berberine	1	1
Blackberry	1	1
Bromelain	1	1
Cannabinoids	1	1
Carnosic Acid	1	1
Celastrol	1	1
Chaga Mushroom (Inonotus obliquus)	1	1
Chickpea	1	1
Coconut Oil	1	1
Cordyceps sinensis	1	1
Cucurbitacin E	1	1
Curry Leaves	1	1
Damnacanthal	1	1
Dates	1	1
Delta-tetrahydrocannabinol (THC)	1	1
Fermented Foods and Beverages	1	1
Garcinia indica	1	1
Geraniol	1	1
Ginger	1	1
Goji	1	1
Gold (nanoparticles)	1	1
Grape Seed Extract	1	1
Guava	1	1
Hibiscus sabdariffa	1	1
Hops	1	1
Hu Zhang (Polygonum cuspidatum)	1	1
Isoflavones	1	1
Isoliquiritigenin	1	1
Japanese mugwort	1	1
Kaempferol	1	1
Kahweol	1	1
Kiwifruit	1	1
Lactobacillus Acidophilus	1	1
Linoleic acid	1	1
Loquat	1	1
Lotus	1	1
Lupeol	1	1
MSM (Methylsulfonylmethane)	1	1
Mango	1	1
Milk Thistle	1	1
Myricetin	1	1
Nigella sativa (aka Black Seed)	1	1
Noni	1	1
Olive	1	1
Oolong tea	1	1
Palmitic acid	1	1
Passion Flower	1	1
Peony	1	1
Perilla	1	1
Prickly Pear Cactus	1	1
Procyanidin B2	1	1
Puerarin	1	1
Pycnogenol (Pine Bark)	1	1
Radish	1	1
Red Sage	1	1
Reishi Mushroom	1	1
Rhubarb	1	1
Rice: Black	1	1
Saffron	1	1
Safranal	1	1
Sandalwood	1	1
Seaweed: Brown	1	1
Sesamol	1	1
Shikonin	1	1
Skullcap: Chinese	1	1
Stilbenes	1	1
Tangeretin	1	1
Tannic Acid	1	1
Urolithin A	1	1
Vitamin C	1	1
Vitamin E	1	1
Vitamin E: Gamma-tocotrienol	1	1
Vitamin K	1	1
Watercress	1	1
Wormwood	1	1
Xanthohumol	1	1
Xanthones	1	1
Zerumbone	1	1
acetyl-11-keto-beta-boswellic acid	1	1

Name	AC	CK
Meat	2	20
Bisphenol A	2	3
Benzo(a)pyrene	1	1
Electronic Cigarettes	1	1
Ethanol	1	1
Zoledronic Acid	1	1

Name	AC	CK
Light-Emitting Diodes (LEDs) Therapy	2	2
Photodynamic therapy	1	2
Laser Treatment: Low-Level	1	1

Name	AC	CK	Focus
Microwave Cooking	1	1

[+]

Coffee consumption appears to have a protective benefit in oral cancer.Mar 31, 2016

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Pubmed Data : Oral Surg Oral Med Oral Pathol Oral Radiol. 2016 Apr ;121(4):381-389.e1. Epub 2016 Jan 4. PMID: 26972538

Article Published Date : Mar 31, 2016

Study Type : Meta Analysis

Additional Links

Substances : Coffee

Diseases : Oral Cancer, Oral Cancer: Prevention

Additional Keywords : Risk Reduction

[+]

Coffee intake was associated with reduced risk of oral, pharynx, liver, colon, prostate, endometrial cancer and melanoma, but increased lung cancer risk.Sep 25, 2016

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Pubmed Data : Sci Rep. 2016 Sep 26 ;6:33711. Epub 2016 Sep 26. PMID: 27665923

Article Published Date : Sep 25, 2016

Study Type : Meta Analysis

Additional Links

Substances : Coffee

Diseases : Colon Cancer, Endometrial Cancer, Liver Cancer, Lung Cancer, Melanoma, Oral Cancer, Prostate Cancer

Pharmacological Actions : Chemopreventive

Additional Keywords : Risk Reduction

[+]

Consumption of apples is associated with a reduced risk of cancer in different anatomical sites.Mar 21, 2016

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Pubmed Data : Public Health Nutr. 2016 Mar 22:1-15. Epub 2016 Mar 22. PMID: 27000627

Article Published Date : Mar 21, 2016

Study Type : Meta Analysis

Additional Links

Substances : Apples

Diseases : Breast Cancer, Colorectal Cancer, Esophageal Cancer, Oral Cancer

Additional Keywords : Risk Reduction

[+]

The consumption of fruit and vegetables is associated with a reduced risk of oral cancer.Apr 30, 2006

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Pubmed Data : Am J Clin Nutr. 2006 May ;83(5):1126-34. PMID: 16685056

Pubmed Data : Int J Oral Maxillofac Surg. 2017 Jul 14. Epub 2017 Jul 14. PMID: 28716471

Article Published Date : Jul 13, 2017

Study Type : Human Study

Additional Links

Diseases : C-Reactive Protein, Inflammation, Oral Cancer

[+]

Chemopreventive synergism between green tea extract and curcumin in patients with potentially malignant oral disorders.Apr 30, 2020

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Pubmed Data : J Contemp Dent Pract. 2020 May 1 ;21(5):521-531. Epub 2020 May 1. PMID: 32690834

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Pubmed Data : Cancer Prev Res (Phila). 2015 Dec 23. Epub 2015 Dec 23. PMID: 26701664

Article Published Date : Dec 22, 2015

Study Type : Human Study

Additional Links

Substances : Black Raspberry

Diseases : Oral Cancer

Pharmacological Actions : Anti-Inflammatory Agents, Apoptotic, Chemopreventive

Additional Keywords : Gene Expression Regulation

[+]

The mean C-reactive protein levels were higher in patients with oral premalignant lesions compared to controls.Nov 02, 2015

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Pubmed Data : Biotech Histochem. 2015 Nov 3:1-6. Epub 2015 Nov 3. PMID: 26529498

Article Published Date : Nov 02, 2015

Study Type : Human Study

Additional Links

Diseases : C-Reactive Protein, Inflammation, Oral Cancer, Squamous cell carcinoma

Additional Keywords : Risk Factors

[+]

The risk of oral cancer and the high consumption of thermally processed meat containing mutagenic and carcinogenic compounds.Apr 06, 2024

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Pubmed Data : Mol Biotechnol. 2023 Dec 16. Epub 2023 Dec 16. PMID: 38103098

Article Published Date : Dec 15, 2023

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Astaxanthin

Diseases : Oral Cancer

Pharmacological Actions : Radiosensitizer

[+]

Bilberry powder has anticarcinogenic effects on oral carcinoma.Aug 21, 2021

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[+]

Bovine lactoferrin reverses programming of epithelial-to-mesenchymal transition to mesenchymal-to-epithelial transition in oral squamous cell carcinoma.Jan 08, 2018

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Pubmed Data : Biochem Biophys Res Commun. 2018 12 9 ;507(1-4):142-147. Epub 2018 Nov 8. PMID: 30415774

Article Published Date : Jan 08, 2018

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Lactoferrin

Diseases : Cancer Metastasis, Oral Cancer, Squamous cell carcinoma

Pharmacological Actions : Anti-metastatic, Chemotherapeutic

[+]

Caffeic acid phenethyl ester increased NDRG1 expression through phosphorylation of ERK1/2 to repress oral squamous cell carcinoma cells growth.Feb 08, 2017

Pubmed Data : Singapore Med J. 2009 Feb;50(2):139-46. PMID: 19296028

Article Published Date : Feb 01, 2009

Study Type : Animal Study

Additional Links

Substances : Curcumin, Piperidines

Diseases : Oral Cancer, Oxidative Stress, Squamous cell carcinoma

Pharmacological Actions : Anticarcinogenic Agents, Antioxidants

[+]

Curcumin and turmeric inhibit experimental tumorigenesis and DNA adduct formation.Jan 01, 1998

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Pubmed Data : Nutr Cancer. 1998;30(2):163-6. PMID: 9589436

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Pubmed Data : PLoS One. 2012 ;7(4):e34628. Epub 2012 Apr 2. PMID: 22485181

Pubmed Data : Nutr Cancer. 2008;60(1):69-74. PMID: 18444138

Article Published Date : Jan 01, 2008

Study Type : Animal Study

Additional Links

Substances : Grapefruit

Diseases : Oral Cancer

[+]

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Pubmed Data : BMC Cancer. 2016 ;16(1):245. Epub 2016 Mar 24. PMID: 27012679

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Pubmed Data : Front Pharmacol. 2022 ;13:1098374. Epub 2023 Jan 5. PMID: 36686704

Article Published Date : Dec 31, 2021

Study Type : Animal Study

Additional Links

Substances : Polypodium leucotomos

Diseases : Oral Cancer

Pharmacological Actions : Anticarcinogenic Agents

[+]

Pre-clinical studies to demonstrate the potential of black raspberry extracts on the prevention of OSCC.Jan 16, 2017

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Pubmed Data : Chem Res Toxicol. 2017 01 17 ;30(1):126-144. Epub 2016 Dec 2. PMID: 28092946

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Pubmed Data : Cell Death Dis. 2020 May 18 ;11(5):381. Epub 2020 May 18. PMID: 32424132

Turmeric and catechin are effective chemopreventive agent. Dec 01, 1994

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Pubmed Data : J Ethnopharmacol. 1994 Dec;44(3):211-7. PMID: 7898128

Article Published Date : Dec 01, 1994

Study Type : Animal Study

Additional Links

Substances : Catechin , Curcumin

Diseases : Benzo[a]pyrene-induced Toxicity , Gastric Cancer, Oral Cancer

Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive

[+]

Verbascoside has potential use as a potent anticancer agent in oral squamous cell carcinoma therapeutic strategies.Aug 14, 2018

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Pubmed Data : Int J Cancer. 2018 Aug 15 ;143(4):980-991. Epub 2018 Apr 16. PMID: 29536537

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Pubmed Data : Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Jul 4. Epub 2020 Jul 4. PMID: 32868254

Article Published Date : Jul 03, 2020

Study Type : In Vitro Study

Additional Links

Substances : Nobiletin

Diseases : Oral Cancer

Pharmacological Actions : Antiproliferative , Apoptotic

Additional Keywords : Selective Cytotoxicity

[+]

[+]

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Pubmed Data : Onco Targets Ther. 2020 ;13:13183-13189. Epub 2020 Dec 29. PMID: 33402832

Article Published Date : Dec 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Allicin

Diseases : Oral Cancer, Squamous cell carcinoma

Pharmacological Actions : Antiproliferative

[+]

Aloe-emodin induces apoptosis in human oral squamous cell carcinoma SCC15 cells.Nov 06, 2018

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Pubmed Data : Biochim Biophys Acta. 2013 May 29. Epub 2013 May 29. PMID: 23726989

Article Published Date : May 28, 2013

Study Type : In Vitro Study

Additional Links

Substances : Astaxanthin

Diseases : Oral Cancer

Pharmacological Actions : Apoptotic, Erk/MAP Inactivation, Receptor activator of NF-κB (RANK) gene expression

[+]

Avastin promotes the migration of two of the cancer cell lines.Dec 31, 2014

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Pubmed Data : Asian Pac J Cancer Prev. 2015 ;16(15):6501-6. PMID: 26434865

Article Published Date : Dec 31, 2014

Study Type : In Vitro Study

Additional Links

Diseases : Oral Cancer, Tongue Cancer

Additional Keywords : Risk Factors

[+]

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2016 Nov ;97:336-345. Epub 2016 Sep 28. PMID: 27693243

Article Published Date : Oct 31, 2016

Study Type : In Vitro Study

Additional Links

Substances : Benzyl isothiocyanate

Diseases : Oral Cancer, Oxidative Stress

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest

Additional Keywords : Isothiocyanates

[+]

Berry extracts inhibit growth and stimulate apoptosis of human cancer cells in vitro.Dec 12, 2006

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Pubmed Data : J Agric Food Chem. 2006 Dec 13 ;54(25):9329-39. PMID: 17147415

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Pubmed Data : J Nutr Biochem. 2016 Jun 19 ;35:37-47. Epub 2016 Jun 19. PMID: 27371785

Article Published Date : Jun 18, 2016

Study Type : In Vitro Study

Additional Links

Substances : Blueberry

Diseases : Oral Cancer, Oral Cancer: Prevention, Squamous cell carcinoma

Pharmacological Actions : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Anticarcinogenic Agents, MicroRNA modulator, NF-kappaB Inhibitor, Vascular Endothelial Growth Factor Inhibitors

[+]

Brown algae-derived fucoidan exerts oxidative stress-dependent antiproliferation on oral cancer cells.Apr 25, 2022

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Pubmed Data : Pharmacology. 2010 ;85(6):328-35. Epub 2010 Jun 2. PMID: 20516734

Article Published Date : Dec 31, 2009

Study Type : In Vitro Study

Additional Links

Substances : Cannabinoids , Delta-tetrahydrocannabinol (THC)

Diseases : Oral Cancer

Pharmacological Actions : Anti-Tumor, Antiproliferative

Additional Keywords : Dose Response

[+]

Capsaicin has an anti-cancer role in oral squamous cell carcinoma.May 31, 2022

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Compounds from noni have potential for used as anti tumor agents for oral cancer therapy.Dec 28, 2017

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Pubmed Data : Asian Pac J Cancer Prev. 2017 Dec 29 ;18(12):3333-3341. Epub 2017 Dec 29. PMID: 29286228

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Pubmed Data : Food Chem Toxicol. 2019 Feb ;124:400-410. Epub 2018 Dec 18. PMID: 30576710

Article Published Date : Jan 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Cordyceps sinensis

Diseases : Oral Cancer, Squamous cell carcinoma

Pharmacological Actions : Apoptotic, Radiosensitizer

[+]

Cordyceps militaris fraction exhibited strong anticancer activity against oral squamous carcinoma KB cells.Dec 31, 2017

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Pubmed Data : Neoplasma. 2023 Feb ;70(1):114-122. Epub 2023 Jan 27. PMID: 36704921

Article Published Date : Jan 31, 2023

Study Type : In Vitro Study

Additional Links

Substances : Salvia miltiorrhiza

Diseases : Oral Cancer, Squamous cell carcinoma

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Autophagy Up-regulation

[+]

Cucurbitacin E is an effective inhibitor of oral squamous cell carcinoma tumors.Dec 31, 2012

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Pubmed Data : Int J Mol Sci. 2013 ;14(8):17147-56. Epub 2013 Aug 20. PMID: 23965977

[+]

Cytotoxic effects of mangosteen pericarp extracts on oral cancer and cervical cancer cells. Aug 31, 2020

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Pubmed Data : J Oral Maxillofac Pathol. 2019 Jan-Apr;23(1):104-107. PMID: 31110425

Article Published Date : Dec 31, 2018

Study Type : In Vitro Study

Additional Links

Substances : Amygdalin (laetrile)

Diseases : Oral Cancer

Pharmacological Actions : Antiproliferative , Apoptotic

[+]

Eugenol inhibits the biological activities of an oral squamous cell carcinoma cell line SCC9 via targeting MIF.Mar 23, 2022

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Pubmed Data : Anticancer Agents Med Chem. 2022 Mar 24. Epub 2022 Mar 24. PMID: 35331101

Article Published Date : Mar 23, 2022

Study Type : In Vitro Study

Additional Links

Substances : Eugenol

Diseases : Oral Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor

[+]

Evaluation of apoptotic effect of crocin, cisplatin, and their combination in human oral squamous cell carcinoma cell line HN5.Dec 31, 2020

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Pubmed Data : Med Oncol. 2017 Jan ;34(1):9. Epub 2016 Dec 21. PMID: 28004293

Article Published Date : Dec 31, 2016

Study Type : In Vitro Study

Additional Links

Substances : Fucoidan

Diseases : Cancer Metastasis, Oral Cancer, Squamous cell carcinoma

Pharmacological Actions : Antineoplastic Agents, Matrix metalloproteinase-2 (MMP-2) inhibitor

[+]

Fucoidan/UVC combined treatment exerts preferential antiproliferation in oral cancer cells but not normal cells.Sep 11, 2022

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Pubmed Data : Antioxidants (Basel). 2022 Sep 12 ;11(9). Epub 2022 Sep 12. PMID: 36139871

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Pubmed Data : Int J Oncol. 2013 Jan ;42(1):75-82. Epub 2012 Nov 8. PMID: 23138939

Article Published Date : Dec 31, 2012

Study Type : In Vitro Study

Additional Links

Substances : Vitamin E: Gamma-tocotrienol

Diseases : Cancers: Drug Resistant, Oral Cancer

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Chemosensitizer, NF-kappaB Inhibitor

Additional Keywords : Chemotherapeutic Synergy: Docetaxel

[+]

Garcinol may be a potential chemopreventive or chemotherapeutic agent for treatment of oral squamous cell carcinoma.Dec 11, 2015

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Pubmed Data : Tumour Biol. 2015 Dec 12. Epub 2015 Dec 12. PMID: 26662963

Article Published Date : Dec 11, 2015

Study Type : In Vitro Study

Additional Links

Substances : Garcinia indica

Diseases : Oral Cancer

Pharmacological Actions : Anti-Inflammatory Agents, Antiproliferative , Apoptotic, Chemopreventive, NF-kappaB Inhibitor

[+]

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Pubmed Data : Environ Toxicol. 2018 Jun ;33(6):679-685. Epub 2018 Apr 16. PMID: 29663662

Article Published Date : May 31, 2018

Study Type : In Vitro Study

Additional Links

Substances : Isoflavones

Diseases : Oral Cancer, Squamous cell carcinoma

Pharmacological Actions : Antiproliferative , Apoptotic

[+]

Goji berry inhibits the proliferation, adhesion, and migration of oral cancer cells.Dec 31, 2021

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Pubmed Data : J Ethnopharmacol. 2002 Aug;81(3):357-64. PMID: 12127237

Article Published Date : Aug 01, 2002

Study Type : In Vitro Study

Additional Links

Substances : Kiwifruit

Diseases : HIV Infections, Oral Cancer, Oxidative Stress, Pseudomonas aeruginosa

Pharmacological Actions : Anti-Bacterial Agents, Antioxidants

Additional Keywords : Plant Extracts

[+]

Lactobacillus extract might reduce the growth and viability of the mouth epidermal carcinoma cells and oral squamous cell carcinoma cell lines.Aug 31, 2023

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Pubmed Data : Onco Targets Ther. 2019 ;12:4427-4435. Epub 2019 Jun 5. PMID: 31239711

Article Published Date : Dec 31, 2018

Study Type : In Vitro Study

Additional Links

Substances : Flavonoids, Licorice

Diseases : Oral Cancer, Squamous cell carcinoma

Pharmacological Actions : Anti-metastatic, Antiproliferative

[+]

Licochalcone B induces apoptosis of human oral squamous cell carcinoma through the extrinsic- and intrinsic-signaling pathways.Mar 31, 2016

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Pubmed Data : J Formos Med Assoc. 2021 Feb 4. Epub 2021 Feb 4. PMID: 33551310

Article Published Date : Feb 03, 2021

Study Type : In Vitro Study

Additional Links

Substances : Magnolol

Diseases : Oral Cancer

Pharmacological Actions : Anti-Inflammatory Agents, Chemosensitizer, Interleukin-6 Downregulation, STAT3 Inhibitor

Additional Keywords : Cancer Stem Cells, Chemotherapeutic Synergy: Cisplatin

[+]

Magnolol triggers caspase-mediated apoptotic cell death in human oral cancer cells.Sep 21, 2021

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Pubmed Data : Pharmaceutics. 2023 Feb 7 ;15(2). Epub 2023 Feb 7. PMID: 36839884

Article Published Date : Feb 06, 2023

Study Type : In Vitro Study

Additional Links

Substances : Lactoferrin

Diseases : Oral Cancer, Squamous cell carcinoma

Pharmacological Actions : Anti-metastatic, Antiproliferative , Matrix metalloproteinase-1 (MMP-1) inhibitor, Matrix metalloproteinase-3 (MMP-3) inhibitor

[+]

Mucoadhesive film containing α-mangostin shows potential role in oral cancer treatment.Jan 09, 2021

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Pubmed Data : Oncol Rep. 2019 Jan 28. Epub 2019 Jan 28. PMID: 30720102

Article Published Date : Jan 27, 2019

Study Type : In Vitro Study

Additional Links

Substances : Hu Zhang (Polygonum cuspidatum)

Diseases : Cancers: Drug Resistant, Oral Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Autophagy Up-regulation

[+]

Palmitic acid of Musa Paradisiaca induces apoptosis through caspase-3 in human oral squamous cell carcinoma.Sep 30, 2022

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Pubmed Data : Eur Rev Med Pharmacol Sci. 2022 Oct ;26(19):7099-7114. PMID: 36263558

Article Published Date : Sep 30, 2022

Study Type : In Vitro Study

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Substances : Banana, Palmitic acid

Diseases : Oral Cancer, Squamous cell carcinoma

Pharmacological Actions : Antiproliferative , Apoptotic

Additional Keywords : Plant Extracts

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Passiflora mollissima seed extract induced antiproliferative and cytotoxic effects on CAL 27 spheroids.Dec 31, 2021

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Pubmed Data : Pak J Biol Sci. 2019 Jan ;22(12):580-584. PMID: 31930856

Article Published Date : Dec 31, 2018

Study Type : In Vitro Study

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Substances : Pomegranate

Diseases : Oral Cancer, Squamous cell carcinoma

Pharmacological Actions : Anti-Apoptotic, Antiproliferative , Chemoprotective Agents

Additional Keywords : Chemothapeutic Synergy: 5-flourouracil

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Pomegranate Extract induces mitochondrial dysfunction and apoptosis of oral cancer cells.Jul 12, 2021

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Pubmed Data : Antioxidants (Basel). 2021 Jul 13 ;10(7). Epub 2021 Jul 13. PMID: 34356350

Article Published Date : Jul 12, 2021

Study Type : In Vitro Study

Additional Links

Substances : Pomegranate

Diseases : Oral Cancer

Pharmacological Actions : Antiproliferative , Apoptotic

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Pubmed Data : Steroids. 2024 May ;205:109393. Epub 2024 Mar 6. PMID: 38458369

Article Published Date : Apr 30, 2024

Study Type : In Vitro Study

Additional Links

Substances : Diosgenin

Diseases : Oral Cancer, Squamous cell carcinoma

Pharmacological Actions : Antiproliferative , Apoptotic, Matrix metalloproteinase-2 (MMP-2) inhibitor

[+]

Procyanidin B2 inhibits angiogenesis and cell growth in oral squamous cell carcinoma cells.Dec 31, 2021

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Pubmed Data : Bioengineered. 2022 03 ;13(3):6500-6508. PMID: 35220896

Article Published Date : Dec 31, 2021

Study Type : In Vitro Study

Additional Links

Substances : Procyanidin B2

Diseases : Oral Cancer

Pharmacological Actions : Angiogenesis Inhibitors, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Proanthocyanidins

[+]

Pterostilbene caused autophagy and apoptosis in human oral cancer cells.May 31, 2015

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Pubmed Data : Oral Oncol. 2015 Jun ;51(6):593-601. Epub 2015 Apr 14. PMID: 25883032

Article Published Date : May 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Pterostilbene

Diseases : Oral Cancer

Pharmacological Actions : Apoptotic, Autophagy Inhibitors

[+]

Pterostilbene may elicit an oral anticancer response in drug-resistant cells.Mar 01, 2018

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2020 Feb 10 ;25(3). Epub 2020 Feb 10. PMID: 32050534

Article Published Date : Feb 09, 2020

Study Type : In Vitro Study

Additional Links

Substances : Quercetin

Diseases : Oral Cancer, Squamous cell carcinoma

Pharmacological Actions : Anti-metastatic, Antiproliferative

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View the Evidence: 363 Abstracts with Oral Cancer Research

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Coffee consumption appears to have a protective benefit in oral cancer.Mar 31, 2016

Coffee intake was associated with reduced risk of oral, pharynx, liver, colon, prostate, endometrial cancer and melanoma, but increased lung cancer risk.Sep 25, 2016

Consumption of apples is associated with a reduced risk of cancer in different anatomical sites.Mar 21, 2016

The consumption of fruit and vegetables is associated with a reduced risk of oral cancer.Apr 30, 2006

The consumption of fruit and vegetables was found to be associated with a reduced risk of oral cancer. Dec 31, 2006

The studies included in this review and meta-analysis showed an inverse association between citrus fruit intake and oral cancer.May 09, 2018

A pro-oxidant combination of resveratrol and copper down-regulates hallmarks of cancer and immune checkpoints in patients with advanced oral cancer.Dec 31, 2021

An omega-3 fatty acid and L-arginine supplement improves blood protein concentrations and reduces C-reactive protein in postsurgical patients with head and neck cancer.Jun 01, 2008

C-reactive protein can be added as an extension to known clinicopathologic parameters to predict the prognosis in oral squamous cell carcinoma.Jul 13, 2017

Chemopreventive synergism between green tea extract and curcumin in patients with potentially malignant oral disorders.Apr 30, 2020

Early human safety study of turmeric oil (Curcuma longa oil) administered orally in healthy volunteers.Oct 31, 2003

Early human safety study of turmeric oil (Curcuma longa oil) administered orally in healthy volunteers.Oct 31, 2003

Processed meat intake was positively associated with head-neck cancer.May 31, 2017

Suppression of pro-inflammatory and pro-survival biomarkers in oral cancer patients consuming a black raspberry phytochemical-rich troche.Dec 22, 2015

The mean C-reactive protein levels were higher in patients with oral premalignant lesions compared to controls.Nov 02, 2015

The risk of oral cancer and the high consumption of thermally processed meat containing mutagenic and carcinogenic compounds.Apr 06, 2024

These results show that serum parathyroid hormone was significantly higher in oral squamous cell carcinoma patients than in control subjects.Jul 31, 2015

This study found high serum levels of retinol and α-tocopherol confer some protection against oral cancer risk.Dec 31, 2013

This study provides supportive evidence that oolong tea consumption may have a potentially beneficial effect in preventing oral squamous cell carcinoma.Dec 31, 2021

Parthenolide is a strong apoptotic inducer that deserves the further investigations for potential chemotherapeutic agent of human oral cancers.May 31, 2015

Resveratrol-induced autophagy and apoptosis in cisplatin-resistant human oral cancer.Jan 29, 2017

Sanguinarine induces apoptosis of human oral squamous cell carcinoma KB cells.Jul 31, 2016

Allyl isothiocyanate suppresses the proliferation in oral squamous cell carcinoma.Sep 28, 2023

Astaxanthin synergizes with ionizing radiation in oral squamous cell carcinoma.Dec 15, 2023

Bilberry powder has anticarcinogenic effects on oral carcinoma.Aug 21, 2021

Curcumol exerts antitumor effect via inhibiting EGFR-Akt-Mcl-1 signaling. Mar 01, 2023

Fucoidan/hyaluronic acid cross-linked zein nanoparticles loaded with fisetin as a novel targeted nanotherapy for oral cancer.Jun 29, 2023

Hesperidin inhibits oral cancer cell growth.Jan 31, 2024

Palliative management of malodorous squamous cell carcinoma of the oral cavity with Manuka honey.Feb 28, 2015

Resveratrol inhibits proliferation and induces autophagy by blocking SREBP1 expression in oral cancer cells.Nov 25, 2022

Spontaneous remission of a squamous cell carcinoma of the floor of the mouth.Sep 30, 2014

Altered cytokeratin expression during chemoprevention of experimental hamster buccal pouch carcinogenesis by garlic.Feb 28, 2002

Antiproliferative and apoptosis inducing effect of lactoferrin and black tea polyphenol combination on hamster buccal pouch carcinogenesis.Sep 30, 2006

Astaxanthin inhibits the hallmarks of cancer.Jun 27, 2019

Astaxanthin that functions as a potent inhibitor of tumour development and progression.Dec 31, 2013

Bitter melon prevents the development of 4-NQO-induced oral squamous cell carcinoma.Oct 22, 2017

Black raspberry inhibits oral tumors in mice.Jan 21, 2020

Black raspberry restores the expression of the tumor suppressor p120ctn in the oral cavity.Dec 31, 2020

Bovine lactoferrin reverses programming of epithelial-to-mesenchymal transition to mesenchymal-to-epithelial transition in oral squamous cell carcinoma.Jan 08, 2018

Caffeic acid phenethyl ester increased NDRG1 expression through phosphorylation of ERK1/2 to repress oral squamous cell carcinoma cells growth.Feb 08, 2017

Cancer chemoprevention with PV-1, a novel Prunella vulgaris-containing herbal mixture that remodels the tumor immune microenvironment.Dec 31, 2022

Chemopreventive activity of Tualang honey against oral squamous cell carcinoma-in vivo.Mar 12, 2020

Chemopreventive potential of phenolic compounds in oral carcinogenesis.Sep 30, 2014

Chlorophyllin inhibits the development of DMBA-induced hamster buccal pouch carcinogenesis by targeting NF-κB.Feb 29, 2012

Curcumin and piperine prevents chemically-induced oral cancer. Feb 01, 2009

Curcumin and turmeric inhibit experimental tumorigenesis and DNA adduct formation.Jan 01, 1998

Curcumin inhibits the proliferation of human oral cancer cells.Jan 01, 2010

Curcumin, beta-carontein and hesperidin prevent chemically-induced oral cancer.Sep 01, 1994

Curcuminoids combined with gefitinib mediated apoptosis and autophagy of human oral cancer.May 01, 2018

dietary chlorophyllin and ellagic acid that can reverse gene expression signature associated with carcinogenesis.Dec 31, 2011

Dietary turmeric led to a decrease in DMBA-induced tumor burden and multiplicity in animals. Oct 31, 2008

Diosmin functions as a potent inhibitor of tumor development and progression.Sep 30, 2016

Effects of high-dose bisphenol A on the mouse oral mucosa: A possible link with oral cancers.May 03, 2021

Extract of green propolis protects against chemically-induced lingual carcinogenesis in rats.Jun 01, 2011

Flavonoids in grapefruit inhibit the development of oral cancer in the hamster. Jan 01, 2008

Gingerol impedes 7,12-dimethylbenz(a)anthracene-induced inflammation and cell proliferation-associated hamster buccal pouch carcinogenesis.Mar 31, 2021

Ginsenoside M1 induces apoptosis and inhibits the migration of human oral cancer cells.Dec 18, 2020

Honokiol and 5-FU exert a synergistic therapeutic effect on oral squamous cell carcinoma by inducing apoptosis.Jul 27, 2016

Honokiol may induce apoptosis and inhibit the survival/proliferation signaling pathways in oral CSC-like cells.Dec 31, 2015

Hydrogel-based patient-friendly photodynamic therapy of oral potentially malignant disorders.Jan 16, 2022

Hypericum perforatum L is a promising chemopreventive agent.Jun 30, 2021

Impact of dietary vitamin D on initiation and progression of oral cancer.Dec 31, 2019

Inhibitory effect of aloe emodin mediated photodynamic therapy on human oral mucosa carcinoma.Oct 31, 2017

Liquiritigenin exerts the anti-cancer role in oral cancer.Jan 11, 2021

Magnolia extract is effective for the chemoprevention of oral cancer through its ability to inhibit mitochondrial respiration at complex IApr 06, 2020

Modulator effect of mangiferin on biochemical characterization in 7,12-dimethylbenz[a]anthracene induced oral cancer.May 04, 2021

Neem extract exhibits chemopreventive effects on chemically-induced buccal pouch cancer in hamsters.Jun 01, 2005

Oral administration of parthenolide completely prevented tumor formation and significantly reduced the severity of histopathological changes.Aug 11, 2017

Oridonin inhibits oral cancer growth and PI3K/Akt signaling pathway. Mar 31, 2018

Paeonol exhibited protective effects against DMBA induced oral carcinogenesis.Dec 31, 2018

Piperlongumine may serve as an effective therapeutic agent for oral cancer.Jan 31, 2018

Polypodium leucotomos targets multiple aspects of oral carcinogenesis and it is a potential antitumor phytotherapy against tongue cancer growth.Dec 31, 2021

Oral Cancer

View the Evidence:
363 Abstracts with Oral Cancer Research