Mineral Deficiencies

Name	AC	CK
Magnesium	77	658
Selenium	17	139
Vitamin D	4	31
Coenzyme Q10	2	20
Brazil nut	1	10
Collards	1	10
Fiber	1	10
Green Leafy Vegetables	1	10
Zinc	1	10
Thiamine (B-1)	1	1
Vitamin K	1	1

Name	AC	CK
Proton-Pump Inhibitors	10	79
Cisplatin	2	20
Statin Drugs	4	13
Lead	1	10
Mercury	1	10
Metformin	1	10
Omeprazole (trade name Prisolec)	1	10
Antidepressants	1	2
Fructose	1	2
Legumes	1	2
Phytate	1	2
Atorvastatin	1	1
Cerivastatin	1	1
Fenofibrates	1	1

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Circulating and dietary magnesium levels are inversely associated with cardiovascular disease risk.Jun 30, 2013

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Pubmed Data : Eur J Clin Nutr. 2014 Apr ;68(4):510-6. Epub 2014 Feb 12. PMID: 24518747

Article Published Date : Mar 31, 2014

Study Type : Meta Analysis, Review

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Substances : Magnesium

Diseases : C-Reactive Protein, Chronic Disease, Inflammation, Magnesium Deficiency

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Risk Factors, Risk Reduction

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This meta-analysis showed that the serum selenium level of patients with GDM was lower than that in healthy pregnant women.Jan 25, 2022

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Pubmed Data : Diabetes Metab Res Rev. 2022 Jan 26:e3522. Epub 2022 Jan 26. PMID: 35080114

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Pubmed Data : Curr Vasc Pharmacol. 2017 Aug 21. Epub 2017 Aug 21. PMID: 28828979

Article Published Date : Aug 20, 2017

Study Type : Human Study

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Diseases : Cardiovascular Diseases, Magnesium Deficiency, Obesity

Additional Keywords : Risk Factors

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Dietary magnesium intake is inversely associated with hyperuricemia.Dec 31, 2014

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Pubmed Data : PLoS One. 2015 ;10(11):e0141079. Epub 2015 Nov 4. PMID: 26536119

Article Published Date : Dec 31, 2014

Study Type : Human Study

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Substances : Magnesium

Diseases : Hyperuricemia, Magnesium Deficiency

Pharmacological Actions : Uricosuric Agents

Additional Keywords : Risk Factors

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Dietary selenium intakes and musculoskeletal function in very old adults.Jul 11, 2020

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Pubmed Data : Nutrients. 2018 Mar 5 ;10(3). Epub 2018 Mar 5. PMID: 29510564

Article Published Date : Mar 04, 2018

Study Type : Human Study

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Substances : Magnesium

Diseases : Diabetes Mellitus: Type 2: Prevention, Heart Disease, Magnesium Deficiency

Pharmacological Actions : Cardioprotective

Additional Keywords : Risk Reduction

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Higher dietary magnesium intake is associated with lower body mass index, waist circumference and serum glucose in Mexican adults.Jan 04, 2018

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Pubmed Data : Int J Cardiol. 2015 Dec 15 ;205:142-146. Epub 2015 Dec 15. PMID: 26736089

Article Published Date : Dec 14, 2015

Study Type : Human Study

Additional Links

Diseases : Atrial Fibrillation, Magnesium Deficiency

Additional Keywords : Increased Risk

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In this cohort of middle-aged and older men low serum 25(OH)D3 concentration was associated with increased risk of death mainly in those with lower magnesium intake. Mar 31, 2015

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Pubmed Data : Eur J Epidemiol. 2015 Apr ;30(4):343-7. Epub 2015 Mar 12. PMID: 25762172

Low serum magnesium levels at admission were found to be associated with the presence of post-stroke depression at 3 months after stroke.Nov 30, 2016

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Pubmed Data : Magnes Res. 2015 Aug 1 ;28(3):99-107. PMID: 26507751

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Pubmed Data : J Family Med Prim Care. 2019 May ;8(5):1671-1677. PMID: 31198735

Article Published Date : Apr 30, 2019

Maternal selenium deficiency during gestation is positively associated with the risks for low-birth-weight and small-for-gestational-age.Feb 17, 2021

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Pubmed Data : Eur J Clin Nutr. 2021 Feb 18. Epub 2021 Feb 18. PMID: 33603150

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Pubmed Data : Arch Med Res. 2014 May ;45(4):325-30. Epub 2014 May 9. PMID: 24814039

Article Published Date : Apr 30, 2014

Study Type : Human Study

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Substances : Magnesium

Diseases : C-Reactive Protein, Diabetes Mellitus: Type 2, Magnesium Deficiency

Pharmacological Actions : Anti-Inflammatory Agents, Insulin Sensitizers

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Oral magnesium supplementation improves the metabolic profile and blood pressure of MONW individuals.Jun 30, 2014

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Pubmed Data : Arch Med Res. 2014 Jul ;45(5):388-93. Epub 2014 May 13. PMID: 24830937

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Pubmed Data : Am J Kidney Dis. 2010 Jul;56(1):112-6. Epub 2010 Feb 26. PMID: 20189276

Article Published Date : Jul 01, 2010

Study Type : Human Study

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Diseases : Magnesium Deficiency

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Reaching optimal selenium and vitamin D levels increases the early efficacy of methimazole treatment when selenium and vitamin D levels are suboptimal.Dec 31, 2021

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Pubmed Data : Front Endocrinol (Lausanne). 2022 ;13:886451. Epub 2022 Jun 15. PMID: 35784564

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Pubmed Data : Biol Trace Elem Res. 2014 Jun ;159(1-3):46-51. Epub 2014 Apr 23. PMID: 24752972

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Pubmed Data : J Clin Diagn Res. 2016 Dec ;10(12):ZC59-ZC61. Epub 2016 Dec 1. PMID: 28209006

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Pubmed Data : PLoS One. 2016 ;11(7):e0157541. Epub 2016 Jul 1. PMID: 27367855

Article Published Date : Dec 31, 2015

Study Type : Human Study

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Substances : Coenzyme Q10, Selenium

Diseases : Cardiac Mortality , Mineral Deficiencies: Selenium

Additional Keywords : Risk Reduction

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Symptomatic hypomagnesemia and proton pump inhibitors.Oct 31, 2014

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Pubmed Data : J Lab Physicians. 2015 Jul-Dec;7(2):75-8. PMID: 26417155

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Pubmed Data : Antioxidants (Basel). 2019 Dec 11 ;8(12). Epub 2019 Dec 11. PMID: 31835711

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Pubmed Data : Biol Trace Elem Res. 2016 Jun 24. Epub 2016 Jun 24. PMID: 27339256

Article Published Date : Jun 23, 2016

Study Type : Animal Study

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Diseases : Liver Damage, Mineral Deficiencies: Selenium

Additional Keywords : Risk Factors

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Low magnesium diet alters distribution of macroelements and trace elements in tissues and organs of female rats.Dec 31, 2016

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Pubmed Data : J Trace Elem Med Biol. 2017 Jan ;39:36-42. Epub 2016 Jul 12. PMID: 27908421

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Substances : Magnesium

Diseases : Magnesium Deficiency, Mineral Deficiencies

Additional Keywords : Risk Factors

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Magnesium deficiency affects HNF1β expression in rat liver in vivo and in vitro.Jul 31, 2017

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Pubmed Data : Magnes Res. 2017 Aug 1 ;30(3):98-105. PMID: 29256409

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Pubmed Data : Blood. 1973 Mar;41(3):451-9. PMID: 4690142

Article Published Date : Mar 01, 1973

Study Type : Animal Study

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Substances : Magnesium

Diseases : Anemia: Hemolytic, Magnesium Deficiency

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Magnesium improves cisplatin-mediated tumor killing while protecting against cisplatin-induced nephrotoxicity.Jul 31, 2017

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Pubmed Data : Am J Physiol Renal Physiol. 2017 Aug 1 ;313(2):F339-F350. Epub 2017 Apr 19. PMID: 28424213

Low levels of magnesium could affect the benefits of vitamin D.Feb 28, 2018

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Pubmed Data : J Am Osteopath Assoc. 2018 Mar 1 ;118(3):181-189. PMID: 29480918

Article Published Date : Feb 28, 2018

Study Type : Review

Additional Links

Substances : Magnesium, Vitamin D

Diseases : Magnesium Deficiency

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Magnesium deficiencies tend to increase tumour incidence in animals and humans where this element affects tumour growth, angiogenesis and metastatisation.Dec 31, 2012

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Pubmed Data : Rocz Panstw Zakl Hig. 2013 ;64(3):165-71. PMID: 24325082

Article Published Date : Dec 31, 2012

Study Type : Review

Additional Links

Substances : Magnesium

Diseases : Attention Deficit Hyperactivity Disorder, Cancers: All, Magnesium Deficiency, Oxidative Stress

Pharmacological Actions : Anticarcinogenic Agents

Additional Keywords : Risk Factors

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Magnesium deficiency favours the manifestation of low-grade chronic inflammation in obese subjects.Jan 31, 2017

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Pubmed Data : Lancet. 2004 Mar 13;363(9412):892-4. PMID: 15031036

Pubmed Data : Clin Nutr ESPEN. 2018 Jun ;25:8-17. Epub 2018 Mar 15. PMID: 29779823

Article Published Date : May 31, 2018

Study Type : Review

Additional Links

Substances : Thiamine (B-1)

Diseases : Chronic Disease, Magnesium Deficiency, Obesity, Vitamin B Deficiency

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This review explores the current state of research in the field of PPIH and the proposed mechanisms of this effect. Mar 05, 2016

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The Following are Sub-Topics of Mineral Deficiencies

View the Evidence: 139 Abstracts with Mineral Deficiencies Research

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Circulating and dietary magnesium levels are inversely associated with cardiovascular disease risk.Jun 30, 2013

Dietary magnesium intake and serum magnesium concentrations are inversely associated with the risk of total CVD events.Dec 31, 2012

Low serum level of magnesium seems to be a risk factor for osteoporosis among the postmenopausal women.May 31, 2014

Magnesium orotate is promising not only in treating MVP and compensating for hypomagnesemia, but also in preventing and treating cardiac arrhythmias.Dec 31, 2014

Proton pump inhibitor use may increase the risk of hypomagnesemia.Dec 31, 2013

Selenium levels were associated with several skin diseases and the disease severity.May 19, 2020

Serum magnesium levels are inversely associated with risk of coronary artery disease.May 16, 2018

The evidence from this meta-analysis supports the theory that an inverse relationship between serum magnesium deficiency and ADHD exists.Feb 18, 2019

This meta-analysesa found a dose-response between the proton pump inhibitors use and development of hypomagnesemia.Oct 31, 2019

This meta-analysis and systematic review indicates that dietary magnesium intake is significantly and inversely associated with serum CRP levels.Mar 31, 2014

This meta-analysis showed that the serum selenium level of patients with GDM was lower than that in healthy pregnant women.Jan 25, 2022

"Lower intake of magnesium and dietary fiber increases the incidence of type 2 diabetes in Taiwanese."Oct 31, 2012

Autistic children had higher levels of lead and mercury and lower levels of selenium.Mar 20, 2017

Brazil nut consumption is an effective way to improve selenium status.Feb 01, 2008

Chronic latent magnesium deficiency in obesity decreases positive effects of vitamin d on cardiometabolic risk indicators.Aug 20, 2017

Cisplatin could produce magnesium deficiency in patients undergoing chemotherapy. Dec 31, 2016

COPD is accompanied by a lowered magnesium level and an alteration in antioxidant status due to possible oxidative stress in this disease.Dec 31, 2000

Correction of hypomagnesemia in type 1 diabetic children with oral magnesium supplements is associated with optimization of glycemic control.Feb 28, 2017

Daily consumption of 500 mg magnesium oxide tablets leads to improvements in depression status.Feb 28, 2017

Dietary magnesium intake is associated with the prevalence of periodontitis.Dec 31, 2021

Dietary magnesium intake is inversely associated with hyperuricemia.Dec 31, 2014

Dietary selenium intakes and musculoskeletal function in very old adults.Jul 11, 2020

Drug use is associated with lower plasma magnesium levels in geriatric outpatients.Dec 05, 2018

Ecological associations are consistent with the potential role of selenium and zinc deficiencies in squamous cell oesophageal cancer in Africa.Dec 31, 2014

Effects of Brazil nut consumption on selenium status and cognitive performance in older adults with mild cognitive impairment.Jan 31, 2016

Higher dietary magnesium intake and higher magnesium status are associated with lower prevalence of coronary heart disease in patients with type 2 diabetes.Mar 04, 2018

Higher dietary magnesium intake is associated with lower body mass index, waist circumference and serum glucose in Mexican adults.Jan 04, 2018

Higher selenium concentration was associated with lower all-cause and heart disease mortality among individuals with T2D.Oct 18, 2021

Higher serum magnesium level may be associated with better endothelial function in end stage renal disease patients on hemodialysis.Oct 31, 2016

Hypomagnesaemia was significantly associated with higher prevalence of diabetic nephropathy.Jul 13, 2016

Hypomagnesemia is a common problem in adults with T1D, and it was correlated with poor glycemic control.Dec 31, 2021

Hypomagnesemia is frequently present in patients with diabetes mellitus and it appears that its prevalence increases with the duration of diabetes mellitus.Mar 31, 2019

Hypomagnesemia over prolonged periods was associated with increased risk of atrial fibrillation.Dec 14, 2015

In this cohort of middle-aged and older men low serum 25(OH)D3 concentration was associated with increased risk of death mainly in those with lower magnesium intake. Mar 31, 2015

In this study, NF1 patients consumed an unhealthy diet that was rich in fats and sodium and lacking in fiber, vitamins and minerals, which may influence the severity of the clinical manifestations of NF1.May 31, 2015

Low levels of magnesium were associated with a higher CRP concentration in patients with obstructive sleep apnea.Sep 05, 2016

Low selenium status is associated with increased risk of thyroid disease.Aug 24, 2015

Low serum magnesium and 1-year mortality in alcohol withdrawal syndrome.Aug 31, 2019

Low serum magnesium levels are associated with an increased risk of prediabetes.Apr 30, 2017

Low serum magnesium levels at admission were found to be associated with the presence of post-stroke depression at 3 months after stroke.Nov 30, 2016

Low serum magnesium may be included in pathogenesis of poor glycemic control and abnormal lipid profile in children with type 1 diabetes.Oct 31, 2016

Low serum magnesium were independently associated with all-cause death in patients with prevalent chronic kidney disease.Oct 24, 2017

Lower dietary magnesium intake was associated with higher blood pressure and stroke risk.Sep 30, 2015

Lower dietary magnesium intake was independently associated with greater odds of rapid kidney function decline.Oct 21, 2016

Lower magnesium intake was associated with worse pain and function in knee osteoarthritis.Feb 14, 2018

Lower serum magnesium levels are associated with coronary artery calcification in Mexican subjects.Dec 31, 2015

Lower serum magnesium was associated with aggravated insulin resistance and higher testosterone levels among women with PCOS.Dec 31, 2020

Lower serum Mg level may be conducive to the development of total testosterone deficiency, arterial hypertension, diabetes, and therefore metabolic syndrome.Jul 31, 2015

Magnesium absorption is high from collards in human subjects. Apr 01, 1984

Magnesium deficiency is associated with aneurysmal subarachnoid hemorrhage and resultant delayed ischemia. Feb 01, 2003

Magnesium deficiency is associated with increased risk of diabetic retinopathy and poor glycemic control.Apr 30, 2019

Magnesium deficiency is highly prevalent in cirrhotic patients.Feb 28, 2021

Magnesium deficiency may contribute to osteoporosis promotion associated with gluten-sensitive enteropathy.Jan 01, 1996

Magnesium intake may have an effect on the risk of developing depression.Dec 29, 2015

Magnesium supplementation among women with gestational diabetes had significant beneficial effects on metabolic status and pregnancy outcomes.May 26, 2015

Magnesium supplementation may improve IBD evolution and sleep quality for patients with a deficit of this mineral.May 02, 2022

Maternal selenium deficiency during gestation is positively associated with the risks for low-birth-weight and small-for-gestational-age.Feb 17, 2021

Micronutrient deficiency independently predicted poor health-related quality of life in patients with heart failure.Nov 04, 2015

Myofascial pain as assessed by tender trigger points and 25(OH)D deficiency showed a significant association with cancer.Jul 05, 2017

Oral magnesium supplementation decreases high sensitivity C-reactive protein levels in subjects with prediabetes and hypomagnesemia.Apr 30, 2014

Oral magnesium supplementation improves the metabolic profile and blood pressure of MONW individuals.Jun 30, 2014

Oral magnesium supplementation with MgCl significantly reduces blood pressure in diabetic hypertensive adults with hypomagnesaemia.Apr 01, 2009

Plasma magnesium is inversely associated with Epstein-Barr virus load in peripheral blood and Burkitt lymphomaJan 31, 2018

Proton pump inhibitor use has been associated with hypomagnesemia.Jul 01, 2010

Reaching optimal selenium and vitamin D levels increases the early efficacy of methimazole treatment when selenium and vitamin D levels are suboptimal.Dec 31, 2021

Reduced levels of plasma selenium are associated with increased inflammation and cardiovascular disease.Dec 25, 2020

Relation between serum magnesium level and migraine. Mar 31, 2021

Relationship between long-term use of proton pump inhibitor (PPI) and hypomagnesemia in patients with gastroesophageal reflux disease.Dec 31, 2021

Selenium supplementation could reduce the prevalence of kaschin-beck disease.Jun 11, 2015

Serum 25(OH)D and magnesium levels may serve as important markers of asthma severity.Dec 31, 2015

Serum and seminal plasma selenium deficiency may be a prominent determinant of abnormal sperm parameters and idiopathic male infertility.May 31, 2014

Serum magnesium in migraine patients was significantly lower than the normal population and related to the frequency of migraine attacks, supporting the use of magnesium in prevention and treatment of migraine.Sep 30, 2011

Mineral Deficiencies

View the Evidence:
139 Abstracts with Mineral Deficiencies Research