Melanoma

Name	AC	CK
Coffee	4	60
Vitamin D	14	51
Curcumin	38	46
Vitamin C	18	25
Flavonoids	17	21
Chlorogenic Acid	1	20
Ginsenosides	13	20
Sulforaphane	7	19
Apigenin	7	15
EGCG (Epigallocatechin gallate)	11	15
Chrysin	8	12
Resveratrol	10	12
Quercetin	8	11
Broccoli Sprouts	1	10
Caffeine	1	10
Anthocyanins	6	9
Berberine	8	9
Lichens	5	9
Mistletoe	4	9
Indole-3-Carbinol	7	8
Pterostilbene	6	8
Chaga Mushroom (Inonotus obliquus)	4	7
Fucoidan	7	7
Phellinus Linteus	5	7
Phloretin	3	7
Thymoquinone	6	7
Tocotrienol: Delta	3	7
Ashwagandha	6	6
Cannabinoids	4	6
Cucurbitacin B	3	6
Green Tea	5	6
Isoliquiritigenin	5	6
Olive leaf extract	3	6
Parthenolide	5	6
Polyphenols	5	6
Reishi Mushroom	4	6
Rosemary	2	6
Zerumbone	2	6
Arugula	1	5
Betulinic acid	4	5
Emodin	5	5
Fisetin	4	5
Homeopathic Medicine: All	3	5
Isothiocyanate	1	5
Licorice	5	5
Luteolin	3	5
Xanthohumol	4	5
Aloe Vera	4	4
Astaxanthin	3	4
Capsaicin	2	4
Ginkgo biloba	3	4
Moringa oleifera	4	4
Oleuropein	3	4
Shikonin	4	4
Turkey Tail Mushroom	3	4
Antrodia camphorata	2	3
Baicalein	3	3
Bamboo	2	3
Bee Propolis	3	3
Beta-Elemene	3	3
Cannabidiol	3	3
Cannabinoids: Synthetic	2	3
Cannabis	3	3
Cashew	2	3
Catechin	2	3
Cinnamaldehyde	2	3
Cinnamon	2	3
Collagen	2	3
Ellagic Acid	2	3
Essential Oils: Unspecified	2	3
Fermented Foods and Beverages	2	3
Frankincense	2	3
Gallic Acid	2	3
Genistein	3	3
Grape	2	3
Mulberry	3	3
Nexrutine (Phellodendrom)	2	3
Paeonol	2	3
Piceatannol	3	3
Raspberry	2	3
Tanshinone IIA	2	3
Vitamin A	2	3
Whey	2	3
Acai	1	2
Angelica	1	2
Apple	1	2
Bee Venom	2	2
Benzyl isothiocyanate	2	2
Black Pepper	1	2
Blueberry	2	2
Broccoli	1	2
Burdock	1	2
Caffeic acid phenethyl ester	2	2
Carnosic Acid	2	2
Carnosol	2	2
Carrot	1	2
Celastrol	2	2
Celery	1	2
Cordyceps sinensis	1	2
Crocin	1	2
Cruciferous Vegetables	2	2
Cucurbitacin E	1	2
Dandelion	2	2
Delphinidin	1	2
Diosmin	1	2
Flaxseed	1	2
Ginseng	1	2
Glycyrrhizin	2	2
Hesperidin	1	2
Hibiscus sabdariffa	2	2
Holy Basil	1	2
Horse Chestnut	2	2
Hyperforin	2	2
Kaempferol	1	2
Kiwifruit	2	2
Lemon Peel	1	2
Magnolol	2	2
Melatonin	2	2
Naringenin	2	2
Nicotinamide	1	2
Oleanolic acid	1	2
Olive Oil	2	2
Papaya: Fermented	1	2
Phenethyl isothiocyanate	2	2
Phyllanthus amarus	2	2
Phyllanthus niruri (Stonebreaker)	2	2
Phyllanthus urinaria	2	2
Pomegranate	1	2
Prickly Pear Cactus	1	2
Red Wine	1	2
Red Wine Extract	1	2
Sage	2	2
Salvia miltiorrhiza	2	2
Sandalwood	2	2
Seaweed: Brown	2	2
Soy Protein	1	2
Tea Tree	2	2
Thyme	2	2
Tocotrienol: Alpha	1	2
Triptolide	1	2
Verbascoside	2	2
Vitamin E: Gamma-tocotrienol	2	2
Walnut	2	2
Wasabi	2	2
Wheat Grass	1	2
Xanthones	2	2
Adlay	1	1
Allicin	1	1
Amaranth	1	1
Andrographolide	1	1
Artichoke	1	1
Asiatic Acid	1	1
Bai Zhu	1	1
Banana Peel	1	1
Bay leaf	1	1
Bergamot	1	1
Beta Sitosterol	1	1
Bixin	1	1
Bloodroot	1	1
Bromelain	1	1
Caffeic Acid	1	1
Carotenoids	1	1
Chokeberry	1	1
Citral	1	1
Curcumol	1	1
Daidzein	1	1
Damnacanthal	1	1
Delta-tetrahydrocannabinol (THC)	1	1
Deuterium (heavy water)	1	1
Diosgenin	1	1
Elecampane	1	1
Epicatechin	1	1
Eucalyptus	1	1
Evening Primrose Oil	1	1
Feverfew	1	1
Folic Acid	1	1
Fucoxanthin	1	1
Garlic	1	1
Geum japonicum	1	1
Ginger	1	1
Ginseng (Korean)	1	1
Goldenseal	1	1
Gotu Kola	1	1
Grapefruit	1	1
Gymnema Sylvestre	1	1
Hibiscus rosa-sinensis	1	1
Honokiol	1	1
Huaier (Trametes robiniophila murr)	1	1
Hydroxytyrosol	1	1
Inositol Hexaphosphate	1	1
Lactoferrin	1	1
Lignans	1	1
Loquat Leaves	1	1
Lotus	1	1
Lupeol	1	1
Lutein	1	1
Lycopene	1	1
Mangosteen	1	1
Marigold	1	1
Medicinal Mushrooms	1	1
Modified Citrus Pectin	1	1
Nettle	1	1
Nobiletin	1	1
Okra	1	1
Oleocanthal	1	1
Omega-3 Fatty Acids	1	1
Organosulfur Compounds	1	1
Oridonin	1	1
P-Coumaric Acid	1	1
Patchouli	1	1
Pea	1	1
Pear	1	1
Phlorotannins	1	1
Pine Needle	1	1
Piperidines	1	1
Piperlongumine	1	1
Polygonatum cyrtonema	1	1
Pomelo	1	1
Potato	1	1
Propolis: Bee	1	1
Propolis: Brazillian	1	1
Psychedelics:All	1	1
Rice Bran	1	1
Rose	1	1
Rosemaric Acid	1	1
Royal Jelly	1	1
Rutin	1	1
S-Adenosylmethionine (SAMe)	1	1
Saffron	1	1
Saikosaponin	1	1
Seaweed	1	1
Sesame Seed Oil	1	1
Sesamol	1	1
Sinomenine	1	1
Sophora Flavescens	1	1
Soy	1	1
Squash: Butternut	1	1
Sugar-apple	1	1
Syrian rue	1	1
Terminalia	1	1
Theaflavins	1	1
Theanine	1	1
Tocotrienol: Gamma	1	1
Tocotrienols	1	1
Ursolic Acid	1	1
Vanillin	1	1
Verbena officinalis	1	1
Viruses: Beneficial	1	1
Vitamin B-3 (Niacin)	1	1
Vitamin E	1	1
Vitamin K	1	1
Wheat Germ	1	1
White Button Mushroom	1	1
Wogonin	1	1
Wormwood	1	1
Zataria multiflora	1	1
Zeaxanthin	1	1
beta-Carotene	1	1

Name	AC	CK
Eszopiclone	1	20
Hypnotic Drugs	1	20
Ramelteon	1	20
Zaleplon	1	20
Zolpidem (trade name Ambien)	1	20
Pesticides	2	12
Dl-alpha-tocopherol acetate	1	10
Glyphosate	1	10
Meat	1	10
Mineral Oil	1	10
Statin Drugs	1	10
Acetaminophen	1	2
Cisplatin	1	2
Doxorubicin	1	2
Paclitaxel	1	2
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)	1	1

Name	AC	CK
Sunlight exposure	3	12
Dietary Modification: Mediterranean Diet	1	10
Gerson Therapy	1	10
Light-Emitting Diodes (LEDs) Therapy	2	8
Dietary Modification: Low Carbohydrate	1	2
Photobiomodulation	2	2
Photodynamic therapy	1	2
Thermal Therapy: Far-Infrared	2	2
Exercise	1	1
Heat Therapy	1	1
Light Therapy	1	1
Light Therapy: Red Colored	1	1
Light-Emitting Diode Therapy	1	1

Name	AC	CK
Electromagnetic Field Harms	1	10
Electromagnetic Radiation	1	10
Biopsy Procedure: Sentinel Lymph-Node	1	1
Biopsy: Various Tissue	1	1

[+]

Hypnotic drugs increase the risk of skin cancer.Sep 01, 2008

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Pubmed Data : J Sleep Res. 2008 Sep;17(3):245-50. PMID: 18844818

Article Published Date : Sep 01, 2008

Study Type : Meta Analysis

Additional Links

Diseases : Melanoma, Skin Cancer

Problem Substances : Eszopiclone, Hypnotic Drugs, Ramelteon, Zaleplon, Zolpidem (trade name Ambien)

Adverse Pharmacological Actions : Carcinogenic

[+]

There is some evidence for the beneficial effects of regular coffee consumption on melanoma.Mar 31, 2016

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Pubmed Data : Am J Clin Dermatol. 2016 Apr ;17(2):113-23. PMID: 26547919

Pubmed Data : Melanoma Res. 2002 Feb;12(1):83-90. PMID: 11828262

Article Published Date : Feb 01, 2002

Study Type : Human Study

Additional Links

Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Melanoma

Problem Substances : Dl-alpha-tocopherol acetate

[+]

Evaluation of biodistribution of sulforaphane after administration of oral broccoli sprout extract in melanoma patients.Apr 23, 2018

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Pubmed Data : Cancer Prev Res (Phila). 2018 Apr 24. Epub 2018 Apr 24. PMID: 29691233

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncol Lett. 2017 May ;13(5):3787-3792. Epub 2017 Mar 23. PMID: 28521479

Article Published Date : Apr 30, 2017

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Melanoma, Vitamin D Deficiency

Additional Keywords : Risk Factors

[+]

Red and processed meat intake was inversely associated with melanoma risk in these two cohorts.Apr 22, 2018

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Pubmed Data : J Am Acad Dermatol. 2018 Apr 23. Epub 2018 Apr 23. PMID: 29698709

Click here to read the entire abstract

Pubmed Data : Am J Clin Nutr. 2019 Aug 5. Epub 2019 Aug 5. PMID: 31380561

Article Published Date : Aug 05, 2019

Study Type : Human Study

Additional Links

Diseases : Basal Cell Carcinoma, Melanoma, Skin Cancer

Therapeutic Actions : Dietary Modification: Mediterranean Diet

Pharmacological Actions : Anti-cancer, Anticarcinogenic Agents

[+]

The study suggests an augmented risk of cutaneous melanoma among subjects with exposure to pesticides.Mar 31, 2016

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Pubmed Data : J Occup Environ Med. 2016 Apr ;58(4):370-5. PMID: 27058477

Click here to read the entire abstract

Pubmed Data : Melanoma Res. 2022 10 1 ;32(5):384-387. Epub 2022 Aug 17. PMID: 35979670

Article Published Date : Dec 31, 2021

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Melanoma, Skin Cancer, Vitamin D Deficiency

Additional Keywords : Risk Factors

[+]

An extract of Rosmarinus officinals L. was able to efficiently reduce the proliferation of the human melanoma A375 cells.Dec 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2015 ;10(7):e0132439. Epub 2015 Jul 15. PMID: 26176704

Article Published Date : Dec 31, 2014

Study Type : Human In Vitro

Additional Links

Substances : Rosemary

Diseases : Melanoma

Pharmacological Actions : Antiproliferative , Apoptotic

Additional Keywords : Dose Response, Plant Extracts

[+]

Antiproliferative and proapoptotic effects of erucin, a diet-derived H2S donor, on human melanoma cells.Dec 25, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

[+]

An isocaloric carbohydrate restriction diet and natural AMPK activating agents induce synergistic anticancer effects.Mar 18, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Eur J Cancer Prev. 2015 Mar 19. Epub 2015 Mar 19. PMID: 25747515

Article Published Date : Mar 18, 2015

Study Type : In Vitro Study, Transgenic Animal Study

Additional Links

Substances : Catechin , Curcumin, Quercetin, Resveratrol

Diseases : Liver Cancer, Melanoma

Therapeutic Actions : Dietary Modification: Low Carbohydrate

Pharmacological Actions : AMP-activated protein kinase modulation , Antiproliferative , Chemopreventive, Interleukin-6 Downregulation, SIRT1 Activator

Additional Keywords : Diet Induced Tumor Suppression

[+]

Angelica sinensis has therapeutic effect against melanoma cells in the mouse experimental model.Mar 01, 2007

Article Published Date : May 29, 2006

Study Type : Animal Study

Additional Links

Substances : Chaga Mushroom (Inonotus obliquus)

Diseases : Melanoma

Pharmacological Actions : Immunostimulatory

[+]

Arctium lappa extract suppresses inflammation and inhibits melanoma progression.Jul 28, 2019

Pubmed Data : Phytomedicine. 2021 Dec 22 ;99:153904. Epub 2021 Dec 22. PMID: 35231825

Article Published Date : Dec 21, 2021

Study Type : Animal Study

Additional Links

Substances : Berberine

Diseases : Cancers: All, Melanoma

Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory

Additional Keywords : Tumor Microenvironment

[+]

Betulinic acid augments the inhibitory effects of vincristine on growth and lung metastasis of B16F10 melanoma cells.Apr 18, 2004

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Br J Cancer. 2004 Apr 19 ;90(8):1672-8. PMID: 15083202

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : FASEB J. 2006 Dec ;20(14):2633-5. Epub 2006 Oct 25. PMID: 17065222

Article Published Date : Nov 30, 2006

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Cannabinoids , Cannabinoids: Synthetic

Diseases : Melanoma

Pharmacological Actions : Angiogenesis Inhibitors, Anti-metastatic, Antineoplastic Agents, Antiproliferative , Apoptotic, Cell cycle arrest, Chemotherapeutic

Additional Keywords : Cannabinoid Receptors, Selective Cytotoxicity

[+]

CARI III exerted anti-cancer activity that is comparable to doxorubicin against melanoma in vivo, as well as in vitro.Dec 31, 2013

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2014 ;19(9):14383-95. Epub 2014 Sep 12. PMID: 25221864

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cancers (Basel). 2020 Jan 29 ;12(2). Epub 2020 Jan 29. PMID: 32013122

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Rep. 2018 Oct 24 ;8(1):15726. Epub 2018 Oct 24. PMID: 30356079

Article Published Date : Oct 23, 2018

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Fisetin

Diseases : Melanoma

Pharmacological Actions : Anti-metastatic, Antiproliferative

Additional Keywords : Natural Substances Versus Drugs

[+]

Cordyceps has significant therapeutic action against melanoma cell growth in mice with no adverse side effects.Dec 01, 2004

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Pubmed Data : Clin Exp Pharmacol Physiol. 2004 Dec;31 Suppl 2:S51-3 PMID: 15649290

Article Published Date : Dec 01, 2004

Study Type : Animal Study

Additional Links

Substances : Cordyceps sinensis

Diseases : Melanoma

[+]

Coupling to a cancer cell-specific antibody potentiates tumoricidal properties of curcumin.Aug 14, 2012

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Cancer. 2012 Aug 15 ;131(4):E569-78. Epub 2012 Jan 3. PMID: 21989768

Article Published Date : Aug 14, 2012

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Melanoma

Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor

[+]

Crocin may exhibit significant melanoma tumor remission properties by positively modulating tumor growth related parameters.Dec 31, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Oncol Rep. 2015 Nov 12. Epub 2015 Nov 12. PMID: 26573768

Article Published Date : Nov 11, 2015

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Melanoma

Pharmacological Actions : Anti-metastatic, Antiproliferative , Autophagy Up-regulation, Cell cycle arrest

[+]

Curcumin exerts its in vitro anti-angiogenic and in vivo anti-tumour properties through combined PDE2 and PDE4 inhibition.Jan 31, 2015

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Pubmed Data : Thromb Haemost. 2015 Feb ;113(2):319-28. Epub 2014 Sep 18. PMID: 25230992

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncotarget. 2017 Mar 31. Epub 2017 Mar 31. PMID: 28410190

Article Published Date : Mar 30, 2017

Study Type : Animal Study

Additional Links

Substances : Oleuropein

Diseases : High Fat Diet, Melanoma

Pharmacological Actions : Angiogenesis Inhibitors, Vascular Endothelial Growth Factor A Inhibitor, Vascular Endothelial Growth Factor C Inhibitor, Vascular Endothelial Growth Factor D Inhibitor

[+]

Diosmin has a synergistic effect with interferon-alpha in inhibiting metastatic pulmonary melanoma. Jun 01, 2009

Click here to read the entire abstract

Pubmed Data : Cancer Biother Radiopharm. 2009 Jun;24(3):347-52. PMID: 19538057

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncotarget. 2019 May 28 ;10(37):3472-3490. Epub 2019 May 28. PMID: 31191820

Article Published Date : May 27, 2019

Click here to read the entire abstract

Pubmed Data : Oncol Res. 2006 ;16(5):211-6. PMID: 17294801

Click here to read the entire abstract

Pubmed Data : Free Radic Biol Med. 2015 Jun 25. Epub 2015 Jun 25. PMID: 26119785

Article Published Date : Jun 24, 2015

Study Type : Animal Study

Additional Links

Substances : Vitamin C

Diseases : Melanoma, Melanoma: Metastatic

Pharmacological Actions : Antioxidants, Apoptotic, Chemotherapeutic, Cytotoxic

Additional Keywords : Natural Substances Versus Drugs, Superiority of Natural Substances versus Drugs

[+]

Piper nigrum extract suppresses tumor growth and enhances the antitumor immune response in murine models of breast cancer and melanoma.Sep 30, 2023

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Food Funct. 2015 Sep 2 ;6(9):3022-34. PMID: 26200777

Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Cancer. 2011 Apr 15 ;128(8):1955-65. PMID: 20568104

Article Published Date : Apr 14, 2011

Study Type : Animal Study

Additional Links

Substances : Olive leaf extract

Diseases : Chemotherapy-Induced Toxicity, Malignant Melanoma, Melanoma, Skin Cancer

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Cell cycle arrest, Chemotherapeutic

Additional Keywords : Natural Substance/Drug Antagonism, Natural Substance/Drug Synergy, Plant Leaves, Temozolomide

Problem Substances : Cisplatin, Doxorubicin, Paclitaxel

[+]

Thymoquinone enhances the effect of Gamma Knife in B16-F10 melanoma through inhibition of p-STAT3.Apr 30, 2019

Click here to read the entire abstract

Pubmed Data : World Neurosurg. 2019 May 1. Epub 2019 May 1. PMID: 31054338

Article Published Date : Apr 30, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Thymoquinone

Diseases : Melanoma

Pharmacological Actions : Radiosensitizer

[+]

Topical calcipotriol plus imiquimod immunotherapy for nonkeratinocyte skin cancers.Oct 31, 2023

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : JID Innov. 2023 Nov ;3(6):100221. Epub 2023 Aug 12. PMID: 37731472

Pubmed Data : J Photochem Photobiol B. 2017 Jan ;166:301-310. Epub 2016 Dec 9. PMID: 28024281

Article Published Date : Dec 31, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Acai

Diseases : Melanoma

Therapeutic Actions : Photodynamic therapy

Pharmacological Actions : Antiproliferative , Photosensitizing Agents

Additional Keywords : Plant Oils

[+]

Tumor regression after intravenous administration of targeted vesicles entrapping the vitamin E α-tocotrienol.Jan 27, 2017

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Pubmed Data : J Control Release. 2017 Jan 28 ;246:79-87. Epub 2016 Dec 18. PMID: 27993600

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2010 Jun 10 ;5(6):e11051. Epub 2010 Jun 10. PMID: 20548792

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cancers (Basel). 2021 Jan 29 ;13(3). Epub 2021 Jan 29. PMID: 33572775

Article Published Date : Jan 28, 2021

Study Type : Animal Study

Additional Links

Substances : Xanthohumol

Diseases : Melanoma

Pharmacological Actions : Anti-metastatic, Antiproliferative

[+]

Aloin promotes cell apoptosis by targeting HMGB1-TLR4-ERK axis in human melanoma cells.Dec 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biosci Biotechnol Biochem. 2010;74(4):753-8. PMID: 20445320

Article Published Date : Jan 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : White Button Mushroom

Diseases : Melanoma, Pigmentation Disorders

[+]

A comprehensive assessment of apigenin as an antiproliferative, proapoptotic, antiangiogenic and immunomodulatory phytocompound.Apr 15, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2019 Apr 16 ;11(4). Epub 2019 Apr 16. PMID: 30995771

[+]

Aloe-emodin significantly reduced the proliferation, stemness and invasive potential of melanospheres.Jun 02, 2015

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Pubmed Data : Eur J Pharmacol. 2015 Jun 3 ;762:283-292. Epub 2015 Jun 3. PMID: 26048310

Article Published Date : Jun 02, 2015

Study Type : In Vitro Study

Additional Links

Substances : Emodin

Diseases : Melanoma, Melanoma: Metastatic

Pharmacological Actions : Anti-metastatic, Antiproliferative , Chemotherapeutic, Immunomodulatory

Additional Keywords : Natural Substance/Drug Synergy

[+]

Aloin enhances cisplatin antineoplastic activity in B16-F10 melanoma cells by transglutaminase-induced differentiation.Dec 31, 2012

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Pubmed Data : Amino Acids. 2013 Jan ;44(1):293-300. Epub 2011 Dec 3. PMID: 22139409

Ankaferd hemostat made from five plants has growth inhibitory activity against melanoma cells. Dec 31, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : SAGE Open Med. 2017 ;5:2050312116689519. Epub 2017 Feb 10. PMID: 28293423

Article Published Date : Dec 31, 2016

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Pubmed Data : J Agric Food Chem. 2012 Aug 15 ;60(32):7866-72. Epub 2012 Aug 6. PMID: 22838509

Article Published Date : Aug 14, 2012

Study Type : In Vitro Study

Additional Links

Substances : Eucalyptus

Diseases : Melanoma

Pharmacological Actions : Antiproliferative , Apoptotic

[+]

Antiproliferative activity of walnut proteins and walnut protein hydrolysates.Sep 24, 2017

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Pubmed Data : J Med Food. 2017 Sep 25. Epub 2017 Sep 25. PMID: 28945497

Article Published Date : Sep 24, 2017

Study Type : In Vitro Study

Additional Links

Substances : Walnut

Diseases : Acute Myeloid Leukemia, Melanoma, Prostate Cancer

Pharmacological Actions : Antiproliferative

Additional Keywords : Dose Response, Selective Antiproliferation

[+]

Antiproliferative sesquiterpene lactones from the roots of Inula helenium.Sep 30, 2002

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biol Pharm Bull. 2002 Oct ;25(10):1370-2. PMID: 12392098

Article Published Date : Sep 30, 2002

Study Type : In Vitro Study

Additional Links

Substances : Elecampane

Diseases : Cervical Cancer, Melanoma

Pharmacological Actions : Antiproliferative

Additional Keywords : Plant Extracts

[+]

Antitumorigenic effect of damnacanthal on melanoma cell viability through p53 and NF-κB/caspase-3 signaling pathways.Oct 31, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Planta Med. 2022 Jul 19. Epub 2022 Jul 19. PMID: 35853472

Click here to read the entire abstract

Pubmed Data : Toxicol Appl Pharmacol. 2021 Mar 11 ;418:115484. Epub 2021 Mar 11. PMID: 33716044

Article Published Date : Mar 10, 2021

Study Type : In Vitro Study

Additional Links

Substances : Berberine

Diseases : Melanoma

Pharmacological Actions : Apoptotic, Chemosensitizer

Additional Keywords : Chemotherapeutic Synergy: Cisplatin

[+]

Bergamottin induces DNA damage and inhibits malignant progression in melanoma.Dec 31, 2020

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Pubmed Data : Pharmaceutics. 2020 May 24 ;12(5). Epub 2020 May 24. PMID: 32456290

Article Published Date : May 23, 2020

Study Type : In Vitro Study

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Substances : Caffeic acid phenethyl ester

Diseases : Melanoma

Pharmacological Actions : Cytotoxic

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Cancer glycolytic dependence as a new target of olive leaf extract.Jan 28, 2020

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Pubmed Data : Oncol Lett. 2018 Feb ;15(2):2393-2400. Epub 2017 Dec 14. PMID: 29434949

Article Published Date : Jan 31, 2018

Study Type : In Vitro Study

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Substances : Carnosic Acid

Diseases : Melanoma

Pharmacological Actions : Chemotherapeutic

Additional Keywords : Natural Substance/Drug Synergy

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Carnosic acid impedes cell growth and enhances anti-cancer effects of carmustine and lomustine in melanoma.May 21, 2018

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Pubmed Data : Biosci Rep. 2018 May 22. Epub 2018 May 22. PMID: 29789400

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Pubmed Data : Oncoimmunology. 2022 ;11(1):2019922. Epub 2022 Jan 4. PMID: 35003897

Article Published Date : Dec 31, 2021

Study Type : In Vitro Study

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Diseases : Melanoma

Therapeutic Actions : Thermal Therapy: Far-Infrared

Additional Keywords : Tumor Microenvironment

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Celastrol inhibits mouse B16-F10 melanoma cell survival.May 20, 2024

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Pubmed Data : Discov Oncol. 2024 May 21 ;15(1):178. Epub 2024 May 21. PMID: 38771435

Article Published Date : May 20, 2024

Study Type : In Vitro Study

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Substances : Celastrol

Diseases : Melanoma

Pharmacological Actions : Antiproliferative , Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor

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Pubmed Data : J Agric Food Chem. 2020 Sep 2 ;68(35):9358-9367. Epub 2020 Aug 24. PMID: 32797754

Article Published Date : Sep 01, 2020

Study Type : In Vitro Study

Additional Links

Substances : Chrysin

Diseases : Melanoma

Pharmacological Actions : Anti-metastatic

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Chrysin induces apoptosis and autophagy in human melanoma cells.Jun 20, 2022

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Pubmed Data : Biomedicines. 2022 Jun 21 ;10(7). Epub 2022 Jun 21. PMID: 35884773

Article Published Date : Jun 20, 2022

Study Type : In Vitro Study

Additional Links

Substances : Chrysin

Diseases : Melanoma

Pharmacological Actions : Apoptotic, Autophagy Up-regulation

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Pubmed Data : Ceska Slov Farm. 2016 ;65(1):10-14. PMID: 27118499

Article Published Date : Dec 31, 2015

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Pubmed Data : Phytomedicine. 2019 Jan ;52:117-128. Epub 2018 Sep 28. PMID: 30599890

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Pubmed Data : Mol Biol Rep. 2015 Jan ;42(1):267-75. Epub 2014 Sep 28. PMID: 25262359

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Cytotoxic activity of high dose ascorbic acid is enhanced by 2-deoxy-d-glucose in glycolytic melanoma cells.Feb 08, 2021

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Pubmed Data : Biochem Biophys Res Commun. 2021 Feb 9 ;546:90-96. Epub 2021 Feb 9. PMID: 33578294

Article Published Date : Feb 08, 2021

Study Type : In Vitro Study

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Substances : Vitamin C

Diseases : Melanoma

Pharmacological Actions : Chemotherapeutic

[+]

Cytotoxic effect of Ginkgo biloba kernel extract on HCT116 and A2058 cancer cell lines.Aug 31, 2020

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Pubmed Data : Molecules. 2022 Apr 23 ;27(9). Epub 2022 Apr 23. PMID: 35566081

Article Published Date : Apr 22, 2022

Study Type : In Vitro Study

Additional Links

Substances : Pine Needle

Diseases : Melanoma

Pharmacological Actions : Cytotoxic

Additional Keywords : Plant Extracts

[+]

[+]

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Pubmed Data : Sci Rep. 2016 ;6:19225. Epub 2016 Jan 12. PMID: 26754091

Article Published Date : Dec 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Melanoma

Pharmacological Actions : Antiproliferative , MicroRNA modulator

Additional Keywords : Dose Response, Gene Expression Regulation

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EGCG exerts significant anti-proliferative effects against renal cell cancer and malignant melanoma cells in vitro.May 19, 2009

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Pubmed Data : J Clin Oncol. 2009 May 20 ;27(15_suppl):e22101. PMID: 27963498

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Pubmed Data : Tumour Biol. 2015 Jul ;36(7):5165-70. Epub 2015 Feb 8. PMID: 25663463

Article Published Date : Jun 30, 2015

Study Type : In Vitro Study

Additional Links

Substances : Essential Oils: Unspecified

Diseases : Melanoma

Pharmacological Actions : Antiproliferative , Apoptotic, Immunomodulatory

[+]

Evaluation of anti-oxidant and antimelanogenic effects of the essential oil and extracts of Rosa × damascena in B16F10 murine melanoma cell line.Dec 31, 2022

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Pubmed Data : Iran J Basic Med Sci. 2023 ;26(9):1076-1082. PMID: 37605721

Article Published Date : Dec 31, 2022

Study Type : In Vitro Study

Additional Links

Substances : Rose

Diseases : Melanoma

Pharmacological Actions : Chemotherapeutic

Additional Keywords : Essential Oils

[+]

Evaluation of the antitumour and antiproliferative effect of xanthohumol-loaded PLGA nanoparticles on melanoma.Oct 25, 2021

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Pubmed Data : Materials (Basel). 2021 Oct 26 ;14(21). Epub 2021 Oct 26. PMID: 34771946

Article Published Date : Oct 25, 2021

Study Type : In Vitro Study

Additional Links

Substances : Xanthohumol

Diseases : Melanoma

Pharmacological Actions : Antiproliferative

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View the Evidence: 535 Abstracts with Melanoma Research

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Coffee intake was associated with reduced risk of oral, pharynx, liver, colon, prostate, endometrial cancer and melanoma, but increased lung cancer risk.Sep 25, 2016

Hypnotic drugs increase the risk of skin cancer.Sep 01, 2008

There is some evidence for the beneficial effects of regular coffee consumption on melanoma.Mar 31, 2016

Mineral oil exposures also contribute to the incidence and mortality of lung, melanoma, and possibly esophageal and stomach cancers and of non-Hodgkin's lymphoma in aerospace workers.Oct 01, 2005

A high vitamin D status may benefit prognosis in patients diagnosed with primary melanoma.Mar 22, 2017

consumption of caffeinated coffee was inversely associated with melanoma risk among men.Feb 19, 2017

Decreased vitamin D serum levels at melanoma diagnosis are associated with tumor ulceration and high tumor mitotic rate.Aug 27, 2019

Dl-alpha-tocopherol acetate does not protect against chemotherapy-induced chromosome damage and reduces the level of plasma gamma tocopherol.Feb 01, 2002

Evaluation of biodistribution of sulforaphane after administration of oral broccoli sprout extract in melanoma patients.Apr 23, 2018

Gerson therapy may have therapeutic efficacy in the treatment of melanoma patients.Sep 01, 1995

Increased UVA exposures (indoor light) and decreased cutaneous Vitamin D(3) levels may be responsible for the increasing incidence of melanoma.Apr 01, 2009

Melanoma skin cancer rates increased with decreased levels of vitamin D.Apr 30, 2017

Red and processed meat intake was inversely associated with melanoma risk in these two cohorts.Apr 22, 2018

Statin drug use is associated with increased incidence of melanoma and non-melanoma skin cancers. Oct 01, 2008

The authors of this study concluded that melanoma is associated with exposure to FM broadcasting.Jan 01, 2002

The Mediterranean Diet is associated with lower risk of skin cancer, Aug 05, 2019

The study suggests an augmented risk of cutaneous melanoma among subjects with exposure to pesticides.Mar 31, 2016

The use of sildenafil may be associated with a higher risk of melanoma in men.May 31, 2014

These results suggest that coffee drinking may protect against liver, ovarian, thyroid and endometrial cancers and melanoma.May 17, 2018

Vitamin D deficiency in melanoma patients is associated with worse overall survival.Dec 31, 2021

An extract of Rosmarinus officinals L. was able to efficiently reduce the proliferation of the human melanoma A375 cells.Dec 31, 2014

Antiproliferative and proapoptotic effects of erucin, a diet-derived H2S donor, on human melanoma cells.Dec 25, 2022

Apigenin is a novel therapeutic candidate for melanoma.Feb 13, 2017

Blue LED irradiation induces apoptotic cell death by activating the mitochondria-mediated pathway and reduces the early growth rate of melanoma cells.Dec 31, 2014

Delta tocotrienol might represent an effective option for chemopreventive strategies for melanoma.Dec 31, 2015

The combination of HSP70 with phloretin could be a novel treatment for efficient immunotherapy of intractable cancers such as skin melanoma.Dec 31, 2015

The present study shows that lichen compounds demonstrated strong antioxidant, antimicrobial, and anticancer properties.Oct 14, 2012

Zerumbone has chemotherapeutic effects on human melanoma cells by altering mitochondrial function.Mar 31, 2017

3,3'-Diindolylmethane improves antitumor immune responses of PD-1 blockade via inhibiting myeloid-derived suppressor cells.Jun 29, 2022

Blue light promotes vitamin C-mediated ferroptosis of melanoma through specifically upregulating transporter SVCT2 and generating Fe2.May 30, 2023

Capsaicin exerts therapeutic effects by targeting tNOX-SIRT1 axis and augmenting ROS-dependent autophagy in melanoma cancer cells.Dec 31, 2020

Chrysin-induced regression of angiogenesis in models of melanoma.Jun 05, 2023

Cucurbitacin B-induced G2/M cell cycle arrest of conjunctival melanoma cells.Sep 30, 2022

Ginsenoside Re inhibits melanogenesis and melanoma growth.Aug 31, 2023

Hyaluronidase inhibitor delphinidin inhibits cancer metastasis.Jun 27, 2024

Induced PSIG expression by herbacetin contributes to suppressing the proliferation, migration, and invasion of melanoma cells.Jul 19, 2023

Long-term survival and spontaneous tumor regression in stage IV melanoma.May 31, 2010

Olive leaf extract inhibits metastatic melanoma spread through suppression of epithelial to mesenchymal transition.Sep 30, 2022

Spontaneous regression of a middle ear melanoma. Sep 29, 2021

The use of Iscador as the sole modality for the adjuvant treatment of metastatic melanoma was extremely effective and very well tolerated achieving complete response and absence of all complaints.Apr 30, 2007

Viscum album extracts seems to have a positive potential in malignant cutaneous melanoma.Oct 31, 2017

Restoration of ascorbate from adequate to optimal physiological levels reduced tumor growth rates and moderated HIF-1 pathway activityJan 31, 2015

A lipid-soluble ginseng extract potently inhibited invasion and migration of B16F10 mouse melanoma cells in a dose-dependent manner.Dec 31, 2014

Altogether these data suggest M1 is an efficient candidate for melanoma therapy.Jan 31, 2016

An isocaloric carbohydrate restriction diet and natural AMPK activating agents induce synergistic anticancer effects.Mar 18, 2015

Angelica sinensis has therapeutic effect against melanoma cells in the mouse experimental model.Mar 01, 2007

Antioxidant, anti-inflammatory and antiproliferative effects of the Vitis vinifera L. var. Fetească Neagră and pinot noir pomace extracts. Dec 31, 2019

Antitumor activity of ginsenoside Rg3 in melanoma through downregulation of the ERK and Akt pathways.May 31, 2019

Apigenin induces apoptosis by regulating Akt and MAPK pathways in human melanoma cell A375SM.Nov 30, 2020

Apigenin limited melanoma cell growth and migration and induced a reduced angiogenic reaction limiting melanoma cell development.Dec 31, 2020

Approximately 67% of the initial number of mice survived with no tumor incidence based on macroscopic examination.May 29, 2006

Arctium lappa extract suppresses inflammation and inhibits melanoma progression.Jul 28, 2019

Ascorbate supplementation hinders metastasis, tumor growth and inflammatory cytokine secretion as well as enhanced encapsulation of tumors elicited by melanoma and breast cancer.Dec 31, 2012

Ascorbate supplementation might help reduce the severe side effects that arise from BETi therapy by reducing the dosage necessary for treatment.Nov 26, 2017

Assessment of antihyperlipidemic and antitumor effect of isolated active phytoconstituents from Apium graveolens.Dec 31, 2018

Astaxanthin induces autophagy and apoptosis in murine melanoma B16F10-Nex2 cells.Oct 05, 2023

Bamboo leaf extract has immunopotentiating, antioxidant and antitumor activity. Jan 01, 2010

Berberine mediates tumor cell death by skewing tumor-associated immunosuppressive macrophages to inflammatory macrophages.Dec 21, 2021

Betulinic acid augments the inhibitory effects of vincristine on growth and lung metastasis of B16F10 melanoma cells.Apr 18, 2004

Both ginseng saponins, 20(R)- and 20(S)-ginsenoside-Rg3, possess an ability to inhibit the lung metastasis of tumor cells.Aug 31, 1995

Cannabinoids as a potential new and novel treatment for melanoma.Feb 28, 2019

Cannabinoids inhibit the growth of melanoma cells but not of normal melanocytes.Nov 30, 2006

CARI III exerted anti-cancer activity that is comparable to doxorubicin against melanoma in vivo, as well as in vitro.Dec 31, 2013

Chrysin could be a potentially good candidate for future use in alternative anti-melanoma treatments.Jan 14, 2018

Chrysin enhances anti-tumor immunity response through IL-12-STAT4 signal pathway in B16F10 melanoma.Apr 27, 2022

Cinnamaldehyde enhances antimelanoma activity through covalently binding ENO1 and exhibits a promoting effect with dacarbazine.Jan 28, 2020

Cinnamon extract induces melanoma tumor cell death in an in vivo model. Jun 03, 2010

Codonopsis pilosula polysaccharide in synergy with dacarbazine inhibits mouse melanoma by repolarizing M2-like tumor-associated macrophages into M1-like tumor-associated macrophages.Aug 08, 2021

Comparable efficacy of fisetin and vemurafenib for inhibiting melanoma growth was noted in this study.Oct 23, 2018

Cordyceps has significant therapeutic action against melanoma cell growth in mice with no adverse side effects.Dec 01, 2004

Coupling to a cancer cell-specific antibody potentiates tumoricidal properties of curcumin.Aug 14, 2012

Crocin may exhibit significant melanoma tumor remission properties by positively modulating tumor growth related parameters.Dec 31, 2016

Melanoma

View the Evidence:
535 Abstracts with Melanoma Research