Liver Disease

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76 Substances Researched for Liver Disease
NameACCKFocus
Vitamin D222Locked
L-Carnitine120Locked
Silymarin415Locked
Fermented Foods and Beverages314Locked
Curcumin712Locked
Garlic212Locked
Silibinin212Locked
Coffee110Locked
Lycopene110Locked
Magnesium110Locked
Melatonin47Locked
Flavonoids56Locked
Licorice34Locked
Berberine23Locked
Ginseng (Korean)23Locked
Paeoniflorin23Locked
Resveratrol23Locked
Sulforaphane23Locked
Andrographolide12Locked
Banaba12Locked
Barley12Locked
Blue Honeysuckle12Locked
Blueberry12Locked
Capsaicin12Locked
Carvacrol12Locked
Celery12Locked
Chicory12Locked
Chlorella (Algae)12Locked
Codonopsis lanceolata12Locked
Cysteine (see N-Acetylcysteine)12Locked
Dibenzoylmethane (DBM)12Locked
Eucalyptus12Locked
Fish Oil12Locked
Fucoidan22Locked
Genistein12Locked
Grape12Locked
Hesperidin12Locked
Jujube12Locked
Kombucha Tea12Locked
Lactobacillus Acidophilus12Locked
Lactobacillus rhamnosus GG12Locked
Lupeol12Locked
Maitake Mushroom12Locked
Marijuana12Locked
Milk Thistle22Locked
NAC (N-acetyl-L-cysteine)12Locked
Nutmeg12Locked
Oregano12Locked
Propolis: Brazillian12Locked
Quercetin22Locked
Rosmarinic acid12Locked
Shiitake Mushroom 12Locked
Soursop12Locked
Soy Protein 12Locked
Stevia12Locked
Taurine12Locked
Thymoquinone12Locked
Ashwagandha11Locked
Astaxanthin11Locked
Coenzyme Q1011Locked
Cyanidin 3-glucoside11Locked
Diosmin 11Locked
Emodin11Locked
Ginsenosides11Locked
Indole-3-Carbinol11Locked
Kaempferol11Locked
Mangiferin11Locked
Mugwort11Locked
Nigella sativa (aka Black Seed)11Locked
Nobiletin 11Locked
Probiotics11Locked
Purslane11Locked
Rosemaric Acid11Locked
Royal Jelly11Locked
Tanshinone IIA11Locked
Thistle11Locked
18 Problem Substances Researched for Liver Disease
NameACCKFocus
Gluten220Locked
Levothyroxine220Locked
Wheat220Locked
Atorvastatin211Locked
Proton-Pump Inhibitors211Locked
Statin Drugs211Locked
Fluvastatin110Locked
Gliadin110Locked
Phthalates110Locked
Simvastatin110Locked
High Fructose Corn Syrup24Locked
Acetaminophen23Locked
Concanavalin A12Locked
Glyphosate12Locked
Paracetamol12Locked
Triclosan12Locked
Aspartame11Locked
Bisphenol A 11Locked
5 Therapeutic Actions Researched for Liver Disease
NameACCKFocus
Hepatoprotective12Locked
antioxidant12Locked
Light Therapy: Red Colored11Locked
Photobiomodulation11Locked
Stem Cell Related Therapy11Locked
3 Problematic Actions Researched for Liver Disease
NameACCKFocus
Vaccination: All110Locked
Vaccination: Hepatitis B110Locked
Western Diet12Locked

View the Evidence:
114 Abstracts with Liver Disease Research

[+]

Effect of L-carnitine supplementation on lipid profiles of patients with liver disease.Jun 29, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Prev Nutr Food Sci. 2020 Jun 30 ;25(2):124-132. PMID: 32676462
Article Published Date : Jun 29, 2020
Study Type : Meta Analysis, Review
Additional Links
Substances : L-Carnitine
Diseases : Hepatitis C, Liver Disease
Pharmacological Actions : Hypolipidemic
[+]

Long-term exposure to PM2.5 was associated with increased risk of chronic liver disease.Aug 17, 2022

Pubmed Data : Int J Environ Res Public Health. 2022 Aug 18 ;19(16). Epub 2022 Aug 18. PMID: 36011940
Article Published Date : Aug 17, 2022
Study Type : Meta Analysis
Additional Links
Diseases : Air Pollution Linked Toxicity, Liver Disease
[+]

This study determines the positive efficacy of vitamin D supplementation for chronic liver disease.Apr 30, 2020

Pubmed Data : Medicine (Baltimore). 2020 May ;99(19):e20296. PMID: 32384521
Article Published Date : Apr 30, 2020
Study Type : Meta Analysis, Review
Additional Links
Substances : Vitamin D
Diseases : Liver Disease, Liver Fibrosis
Pharmacological Actions : Anti-Fibrotic, Hepatoprotective
[+]

Air pollution and risk of 32 health conditions: outcome-wide analyses in a population-based prospective cohort.Sep 10, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Med. 2024 Sep 11 ;22(1):370. Epub 2024 Sep 11. PMID: 39256817
Article Published Date : Sep 10, 2024
Study Type : Human Study
Additional Links
Diseases : Air Pollution Linked Toxicity, Atherosclerosis, Cardiovascular Diseases, Diabetes Mellitus: Type 2, Inflammatory Bowel Diseases, Liver Disease, Osteoarthritis, Osteoporosis, Pneumonia, Stroke
[+]

Beneficial effects of silybin treatment after viral eradication in patients with HCV.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:824879. Epub 2022 Feb 2. PMID: 35185575
Article Published Date : Dec 31, 2021
Study Type : Human Study
Additional Links
Substances : Silibinin
Diseases : Hepatitis C, Liver Disease
Pharmacological Actions : Hepatoprotective
[+]

Celiac disease is found in a far higher percentage of patients with end-stage autoimmune liver disease.Apr 01, 2008

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Liver Int. 2008 Apr;28(4):467-76. PMID: 18339073
Article Published Date : Apr 01, 2008
Study Type : Human Study
Additional Links
Diseases : Autoimmune Diseases, Celiac Disease, End-Stage Autoimmune Liver Disease (ESALD), Liver Disease, Organ Transplantation: Liver
Additional Keywords : Diseases that are Linked
Problem Substances : Gluten, Wheat
[+]

Fermented garlic extracts might be effective and safe management options for mild hepatic dysfunction.Jul 31, 2017

Pubmed Data : Eur J Nutr. 2017 Aug ;56(5):1993-2002. Epub 2016 Oct 14. PMID: 27743130
Article Published Date : Jul 31, 2017
Study Type : Human Study
Additional Links
Substances : Fermented Foods and Beverages, Garlic
Diseases : Liver Disease
Pharmacological Actions : Antioxidants, Hepatoprotective
[+]

For every 100 mg increase in intake of magnesium a 49% reduction in the risk for mortality due to liver diseases was found. Dec 19, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Dec 20 ;7(1):17913. Epub 2017 Dec 20. PMID: 29263344
Article Published Date : Dec 19, 2017
Study Type : Human Study
Additional Links
Substances : Magnesium
Diseases : Alcoholic Liver Disease, Liver Disease
Additional Keywords : Risk Reduction
[+]

Hepatitis B vaccine is associated with an increased risk of liver problems in U.S. children less than 6 years old, 1993 and 1994.May 01, 1999

Pubmed Data : Epidemiology. 1999 May;10(3):337-9. PMID: 10230847
Article Published Date : May 01, 1999
Study Type : Human Study
Additional Links
Diseases : Liver Disease, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All, Vaccination: Hepatitis B
[+]

Higher coffee consumption was associated with lower risk of elevated aminotransferase concentration in Korean adults.Nov 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asia Pac J Clin Nutr. 2016 Dec ;25(4):767-775. PMID: 27702720
Article Published Date : Nov 30, 2016
Study Type : Human Study
Additional Links
Substances : Coffee
Diseases : Liver Disease
Pharmacological Actions : Enzyme Inhibitors, Hepatoprotective
[+]

Levothyroxine may be a risk factor for hypoglycaemia in patients with liver disease.Oct 01, 2003

Pubmed Data : J Clin Pharm Ther. 2003 Oct;28(5):355-61. PMID: 14632959
Article Published Date : Oct 01, 2003
Study Type : Human Study
Additional Links
Diseases : Hypoglycemia, Hypothyroidism, Liver Disease
Additional Keywords : Diseases that are Linked
Problem Substances : Levothyroxine
[+]

Levothyroxine use is associated with increased risk of hypoglycemia in patients with liver impairment.Jan 01, 2008

Pubmed Data : Int J Clin Pharmacol Ther. 2008 Jan;46(1):1-13. PMID: 18218292
Article Published Date : Jan 01, 2008
Study Type : Human Study
Additional Links
Diseases : Hypoglycemia, Hypothyroidism, Liver Disease
Problem Substances : Levothyroxine
[+]

Liver failure and damage are rare but severe unintended consequences of statin drug use.Aug 31, 2011

Pubmed Data : J Hepatol. 2011 Aug 31. Epub 2011 Aug 31. PMID: 21889469
Article Published Date : Aug 31, 2011
Study Type : Human Study
Additional Links
Diseases : Chemically-Induced Liver Damage, Liver Damage, Liver Disease, Liver Failure: Drug Induced, Statin-Induced Pathologies
Problem Substances : Atorvastatin, Fluvastatin, Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Hepatotoxic
[+]

National Health and Nutrition Examination Surveys data collected from 1988 to 2008 show that the prevalence of major causes of CLD remained stable, except for NAFLD, which increased steadily, along with the prevalence of metabolic conditions. Jun 01, 2011

Pubmed Data : Clin Gastroenterol Hepatol. 2011 Jun;9(6):524-530.e1. Epub 2011 Mar 25. PMID: 21440669
Article Published Date : Jun 01, 2011
Study Type : Human Study
Additional Links
Diseases : Liver Disease, Nonalcoholic fatty liver disease (NAFLD)
[+]

Patients with chronic liver disease have a high prevalence of anti-tTg antibodies, similar to patients with celiac disease.Jan 01, 2003

Pubmed Data : Scand J Gastroenterol. 2003 Jan;38(1):50-4. PMID: 12608464
Article Published Date : Jan 01, 2003
Study Type : Human Study
Additional Links
Diseases : Cirrhosis: Liver, Liver Disease
Additional Keywords : Anti-Endomysium Antibodies, Anti-tTG
Problem Substances : Gliadin, Gluten, Wheat
[+]

Phthalates exposure of MASLD adults was related to increased risks of IR, prediabetes, and diabetes.Dec 09, 2024

Pubmed Data : Diabetes Metab. 2024 Dec 10 ;51(1):101602. Epub 2024 Dec 10. PMID: 39662798
Article Published Date : Dec 09, 2024
Study Type : Human Study
Additional Links
Diseases : Insulin Resistance, Liver Disease, Phthalate Toxicity , Prediabetes
Additional Keywords : Increased Risk
Problem Substances : Phthalates
[+]

Protective role of lycopene in subjects with liver disease.Feb 17, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2024 Feb 18 ;16(4). Epub 2024 Feb 18. PMID: 38398886
Article Published Date : Feb 17, 2024
Study Type : Human Study
Additional Links
Substances : Lycopene
Diseases : Liver Disease
Pharmacological Actions : Antioxidants
[+]

Proton pump inhibitor treatment is associated with the severity of liver disease and increased mortality in patients with cirrhosis.Dec 18, 2014

Pubmed Data : Aliment Pharmacol Ther. 2014 Dec 19. Epub 2014 Dec 19. PMID: 25523381
Article Published Date : Dec 18, 2014
Study Type : Human Study
Additional Links
Diseases : Liver Cirrhosis, Liver Disease
Problem Substances : Proton-Pump Inhibitors
[+]

Silymarin in high dose is a good choice for improvement of liver biochemical profile and QoL in chronic hepatitis C virus cirrhotic patients.Oct 31, 2017

Pubmed Data : J Interferon Cytokine Res. 2017 Nov ;37(11):480-487. PMID: 29135373
Article Published Date : Oct 31, 2017
Study Type : Human Study
Additional Links
Substances : Silymarin
Diseases : Hepatitis C, Liver Disease
Pharmacological Actions : Hepatoprotective
[+]

A western-style diet increases liver inflammation in mice with experimentally-induced sepsis.Jan 01, 2010

Pubmed Data : BMC Physiol. 2010;10:20. Epub 2010 Oct 19. PMID: 20958969
Article Published Date : Jan 01, 2010
Study Type : Animal Study
Additional Links
Diseases : Liver Disease, Sepsis
Anti Therapeutic Actions : Western Diet
[+]

Andrographolide attenuated MCT-induced HSOS via regulating NRF2-initiated mitochondrial biogenesis and antioxidant response.Oct 10, 2023

Pubmed Data : Cell Biol Toxicol. 2023 Oct 11. Epub 2023 Oct 11. PMID: 37816928
Article Published Date : Oct 10, 2023
Study Type : Animal Study
Additional Links
Substances : Andrographolide
Diseases : Liver Disease, Sinusoidal obstruction syndrome
Pharmacological Actions : Antioxidants, Hepatoprotective, Nrf2 activation
[+]

Betulinic acid can be used as an effective agent in the prevention and treatment of acute liver diseases.Mar 27, 2021

Pubmed Data : Turk J Med Sci. 2021 Mar 28. Epub 2021 Mar 28. PMID: 33773522
Article Published Date : Mar 27, 2021
Study Type : Animal Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity , Liver Damage: Drug-Induced, Liver Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective
Problem Substances : Acetaminophen, Paracetamol
[+]

Blockage of CCL5 may promote liver regeneration.Sep 03, 2019

Pubmed Data : Cell Mol Immunol. 2019 Sep 3. Epub 2019 Sep 3. PMID: 31481754
Article Published Date : Sep 03, 2019
Study Type : Animal Study
Additional Links
Diseases : Liver Damage, Liver Damage: Drug-Induced, Liver Disease
[+]

Blueberry components could regulate histone acetylation and improve liver pathologic changes in rats with carbon tetrachloride-induced disease.Feb 15, 2017

Pubmed Data : Genet Mol Res. 2017 Feb 16 ;16(1). Epub 2017 Feb 16. PMID: 28218781
Article Published Date : Feb 15, 2017
Study Type : Animal Study
Additional Links
Substances : Blueberry
Diseases : Chemically-Induced Liver Damage, Liver Disease, Liver Fibrosis
Pharmacological Actions : Hepatoprotective
[+]

C. sempervirens and J. phoenicea leaf extracts show a remarkable effect in enhancing liver and kidney functions and may thus be of therapeutic potential in treatment hepatotoxicity and nephrotoxicity.Dec 06, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Gastrointest Pharmacol Ther. 2010 Dec 6 ;1(6):123-31. PMID: 21577307
Article Published Date : Dec 06, 2010
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Liver Disease
Therapeutic Actions : antioxidant, Hepatoprotective
Additional Keywords : C. Sempervirens Extract, J. Phoenicea Extract, Liver Enzymes, Plant Extracts
[+]

Cannabidiol, a non-psychoactive component from Cannabis sativa, may have a therapeutic role in ameloriating cognitive and motor impairments associated with chronic liver disease. Sep 01, 2009

Pubmed Data : J Hepatol. 2009 Sep;51(3):528-34. Epub 2009 May 27. PMID: 19596476
Article Published Date : Sep 01, 2009
Study Type : Animal Study
Additional Links
Substances : Marijuana
Diseases : Liver Disease
[+]

Carvacrol obtained from oregano oil significantly increases the liver regeneration rate in rats undergoing partial hepatectomy. Sep 01, 2007

Pubmed Data : Toxicol Sci. 2007 Sep;99(1):190-202. Epub 2007 Mar 30. PMID: 17689059
Article Published Date : Sep 01, 2007
Study Type : Animal Study
Additional Links
Substances : Carvacrol, Oregano
Diseases : Liver Disease
Additional Keywords : Liver Regeneration, Regenerative Substances
[+]

Celery leaves mixed with chicory leaves and barley grains have a liver protective property in hypercholesterolemic rats.Apr 01, 2011

Pubmed Data : Pharmacogn Mag. 2011 Apr ;7(26):151-6. PMID: 21716923
Article Published Date : Apr 01, 2011
Study Type : Animal Study
Additional Links
Substances : Barley, Celery, Chicory
Diseases : Hypercholesterolemia, Liver Disease
Pharmacological Actions : Hepatoprotective
[+]

Chlorella protects the liver from cadmium-induced toxicity in rats.Sep 01, 2008

Pubmed Data : J Med Food. 2008 Sep;11(3):479-85. PMID: 18800895
Article Published Date : Sep 01, 2008
Study Type : Animal Study
Additional Links
Substances : Chlorella (Algae)
Diseases : Cadmium Poisoning , Liver Disease
Pharmacological Actions : Hepatoprotective
[+]

Codonopsis lanceolata protects against stess-induced liver damage. Oct 01, 2009

Pubmed Data : Arch Pharm Res. 2009 Oct;32(10):1441-6. Epub 2009 Nov 8. PMID: 19898808
Article Published Date : Oct 01, 2009
Study Type : Animal Study
Additional Links
Substances : Codonopsis lanceolata
Diseases : Liver Disease
Pharmacological Actions : Antioxidants, Antiproliferative
[+]

Curcumin attenuates oxidative stress and inflammatory response in the early phase after partial hepatectomy with simultaneous intraabdominal infection in rats.Mar 01, 2010

Pubmed Data : J Surg Res. 2010 Mar;159(1):497-502. Epub 2008 Dec 31. PMID: 19321178
Article Published Date : Mar 01, 2010
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Inflammation, Liver Disease, Liver Surgery, Oxidative Stress
Pharmacological Actions : Hepatoprotective
[+]

Curcumin has protective effects against hepatic ischemia/reperfusion injury. Its mechanism might be related to the overexpression of heat shock protein 70 and antioxidant enzymes.Apr 07, 2007

Pubmed Data : World J Gastroenterol. 2007 Apr 7;13(13):1953-61. PMID: 17461496
Article Published Date : Apr 07, 2007
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Liver Disease
Pharmacological Actions : Antioxidants, Apoptotic, Enzyme Inhibitors, Heat Shock Protein Inducer
Additional Keywords : Heat Shock Protein Inducer
[+]

Curcumin works synergistically with erythropoietin to stimulate liver regeneration.May 01, 2008

Pubmed Data : Langenbecks Arch Surg. 2008 May;393(3):325-32. Epub 2008 Feb 27. PMID: 18301913
Article Published Date : May 01, 2008
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Liver Disease
Pharmacological Actions : Antioxidants, Antiproliferative
Additional Keywords : Drug Synergy, Liver Regeneration
[+]

Curcumin, capsaicin and garlic inhibit adverse blood and liver changes associated wtih a high-fat diet in rats.Sep 01, 2004

Pubmed Data : Ann Nutr Metab. 2004 Sep-Oct;48(5):314-20. Epub 2004 Oct 1. PMID: 15467281
Article Published Date : Sep 01, 2004
Study Type : Animal Study
Additional Links
Substances : Capsaicin, Curcumin, Garlic
Diseases : Hyperlipidemia, Liver Disease, Oxidative Stress
Pharmacological Actions : Antioxidants, Hepatoprotective
[+]

Dibenzoylmethane protects against carbon tetrachloride induced acute liver injury.Oct 31, 2017

Pubmed Data : AAPS J. 2017 Nov ;19(6):1703-1714. Epub 2017 Aug 21. PMID: 28828752
Article Published Date : Oct 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Dibenzoylmethane (DBM)
Diseases : Chemically-Induced Liver Damage, Liver Disease
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Hepatoprotective, Nrf2 activation
[+]

Dietary rosmarinic acid supplementation may be beneficial in terms of improving cholestasis-related liver injury.Aug 04, 2017

Pubmed Data : Food Chem Toxicol. 2017 Aug 5 ;108(Pt A):214-223. Epub 2017 Aug 5. PMID: 28789951
Article Published Date : Aug 04, 2017
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid
Diseases : Cholestasis, Liver Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, NF-kappaB Inhibitor
[+]

Efficacy of a Peruvian botanical remedy (Sabell A4+) for treating liver disease and protecting gastric mucosal integrity.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2019 ;2019:5486728. Epub 2019 Oct 24. PMID: 31781272
Article Published Date : Dec 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Curcumin, Soursop
Diseases : Liver Disease
Pharmacological Actions : Gastroprotective, Hepatoprotective
[+]

Eucalyptus and banaba inhibit NASH induced by high-fructose and high-glucose diet in rats.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2015 ;2015:296207. Epub 2015 Apr 27. PMID: 26000287
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Banaba, Eucalyptus
Diseases : High Fructose Diet, Liver Disease, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Fish oil (but not olive oil) improves liver regeneration in rats subjected to partial hepatectomy. Mar 01, 2006

Pubmed Data : Transplant Proc. 2006 Mar;38(2):564-7. PMID: 16549176
Article Published Date : Mar 01, 2006
Study Type : Animal Study
Additional Links
Substances : Fish Oil
Diseases : Liver Disease
[+]

G. frondosa may prevent the further development of NASH by improving the disorder of lipid metabolism in rats.Apr 30, 2015

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2015 May ;40(9):1808-11. PMID: 26323153
Article Published Date : Apr 30, 2015
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom
Diseases : Hepatic Steatosis, Liver Disease
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Hypolipidemic, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Grape juice has a liver protecting properties in rats. Mar 01, 2008

Pubmed Data : J Med Food. 2008 Mar;11(1):127-32. PMID: 18361748
Article Published Date : Mar 01, 2008
Study Type : Animal Study
Additional Links
Substances : Grape
Diseases : Liver Disease
Pharmacological Actions : Antioxidants
[+]

Hepatoprotective and cognitive-enhancing effects of hesperidin against thioacetamide-induced hepatic encephalopathy.Jan 14, 2023

Pubmed Data : Life Sci. 2023 Jan 15 ;313:121280. Epub 2022 Dec 13. PMID: 36526046
Article Published Date : Jan 14, 2023
Study Type : Animal Study
Additional Links
Substances : Hesperidin
Diseases : Hepatic Encephalopathy, Liver Disease, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-1 beta downregulation
[+]

High fat, high fructose, high cholesterol feeding causes severe NASH and cecal microbiota dysbiosis in juvenile ossabaw swine.Sep 11, 2017

Pubmed Data : Am J Physiol Endocrinol Metab. 2017 Sep 12:ajpendo.00015.2017. Epub 2017 Sep 12. PMID: 28899857
Article Published Date : Sep 11, 2017
Study Type : Animal Study
Additional Links
Diseases : Dysbiosis, High Fat Diet, High Fructose Diet, Liver Disease, Obesity
Additional Keywords : Risk Factors
Problem Substances : High Fructose Corn Syrup
[+]

Kombucha tea exhibits anti-stress and liver protecting properties. Sep 01, 2001

Pubmed Data : Biomed Environ Sci. 2001 Sep;14(3):207-13. PMID: 11723720
Article Published Date : Sep 01, 2001
Study Type : Animal Study
Additional Links
Substances : Fermented Foods and Beverages, Kombucha Tea
Diseases : Liver Disease
[+]

Korean ginseng accelerates the rate of liver regeneration and ameliorated the liver injury after partial hepatectomy in rats. Feb 01, 2004

Pubmed Data : J Vet Med Sci. 2004 Feb;66(2):193-5. PMID: 15031549
Article Published Date : Feb 01, 2004
Study Type : Animal Study
Additional Links
Substances : Ginseng (Korean)
Diseases : Liver Disease
Additional Keywords : Liver Regeneration
[+]

Lactobacillus acidophilus-fermented jujube juice ameliorates chronic liver injury.Dec 26, 2023

Pubmed Data : Mol Nutr Food Res. 2023 Dec 27:e2300334. Epub 2023 Dec 27. PMID: 38150643
Article Published Date : Dec 26, 2023
Study Type : Animal Study
Additional Links
Substances : Fermented Foods and Beverages, Jujube, Lactobacillus Acidophilus
Diseases : Liver Damage, Liver Disease
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Lactobacillus rhamnosus GG reduces hepatic fibrosis in animals.Jan 04, 2017

Pubmed Data : Nutr Hosp. 2017 06 5 ;34(3):702-709. Epub 2017 Jun 5. PMID: 28627210
Article Published Date : Jan 04, 2017
Study Type : Animal Study
Additional Links
Substances : Lactobacillus rhamnosus GG
Diseases : Fibrosis, Liver Disease
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Interleukin-6 Downregulation
[+]

Lipid metabolism disorders contribute to hepatotoxicity of triclosan in mice.Sep 23, 2019

Pubmed Data : J Hazard Mater. 2019 Sep 24 ;384:121310. Epub 2019 Sep 24. PMID: 31586915
Article Published Date : Sep 23, 2019
Study Type : Animal Study
Additional Links
Diseases : Chemically-Induced Liver Damage, Liver Disease
Problem Substances : Triclosan
[+]

Lupeol improves bile acid metabolism and metabolic dysfunction-associated steatotic liver disease.Jun 16, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2024 Jun 17 ;177:116942. Epub 2024 Jun 17. PMID: 38889641
Article Published Date : Jun 16, 2024
Study Type : Animal Study
Additional Links
Substances : Lupeol
Diseases : Liver Disease
Pharmacological Actions : Hepatoprotective
Additional Keywords : Gut-liver axis
[+]

Melatonin improves cholestatic liver disease via the gut-liver axis.Dec 31, 2023

Pubmed Data : J Pineal Res. 2024 Jan ;76(1):e12929. Epub 2023 Dec 4. PMID: 38047407
Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Cholestasis, Liver Cirrhosis, Liver Disease
Pharmacological Actions : Gastrointestinal Agents
Additional Keywords : Gut-liver axis
[+]

Melatonin restores liver mitochondrial physiology in old mice.Mar 01, 2003

Pubmed Data : Int J Biochem Cell Biol. 2003 Mar;35(3):367-75. PMID: 12531250
Article Published Date : Mar 01, 2003
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Aging, Liver Disease
Pharmacological Actions : Antioxidants, Hepatoprotective, Regenerative
[+]

N-acetyl cysteine attenuates the sarcopenia and muscle apoptosis induced by chronic liver disease.Sep 16, 2019

Pubmed Data : Curr Mol Med. 2019 Sep 17. Epub 2019 Sep 17. PMID: 31530262
Article Published Date : Sep 16, 2019
Study Type : Animal Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine)
Diseases : Liver Disease, Sarcopenia
Pharmacological Actions : Anti-Apoptotic
[+]

Paeoniflorin is predicted to be a potential therapy for chronic hepatic diseases associated with fibrosis and angiogenesis.Jan 31, 2019

Pubmed Data : Exp Parasitol. 2019 Feb ;197:85-92. Epub 2018 Nov 8. PMID: 30414842
Article Published Date : Jan 31, 2019
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Liver Disease, Schistosomiasis
Pharmacological Actions : Anti-Angiogenic, Anti-Fibrotic, Vascular Endothelial Growth Factor Inhibitors
[+]

Polyphenols from Lonicera caerulea L. berry attenuate experimental nonalcoholic steatohepatitis.Mar 31, 2017

Pubmed Data : Mol Nutr Food Res. 2017 Apr ;61(4). Epub 2017 Feb 15. PMID: 27935258
Article Published Date : Mar 31, 2017
Study Type : Animal Study
Additional Links
Substances : Blue Honeysuckle
Diseases : Liver Disease, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Malondialdehyde Down-regulation
[+]

Resveratrol supplementation considerably restored hepatic changes induced by high fructose corn syrup.Sep 10, 2014

Pubmed Data : Eur J Nutr. 2014 Sep 11. Epub 2014 Sep 11. PMID: 25238689
Article Published Date : Sep 10, 2014
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Liver Disease
Pharmacological Actions : Hepatoprotective, SIRT1 Activator
Additional Keywords : Risk Reduction
Problem Substances : High Fructose Corn Syrup
[+]

Silybin was effective in preventing the methionine-choline deficient-induced increases in hepatic steatosis, fibrosis and inflammation.Sep 05, 2018

Pubmed Data : Dig Dis Sci. 2018 Sep 6. Epub 2018 Sep 6. PMID: 30191499
Article Published Date : Sep 05, 2018
Study Type : Animal Study
Additional Links
Substances : Silibinin
Diseases : Hepatic Steatosis, Liver Disease, Liver Fibrosis
Pharmacological Actions : Anti-Fibrotic, Hepatoprotective
[+]

Soy protein isolate reduces fatty liver in a mouse model of non-alchohlic liver disease. Nov 13, 2010

Pubmed Data : Neurotox Res. 2010 Nov 13. Epub 2010 Nov 13. PMID: 18791133
Article Published Date : Nov 13, 2010
Study Type : Animal Study
Additional Links
Substances : Genistein, Soy Protein
Diseases : Fatty Liver, Liver Disease
[+]

Stevia prevents experimental cirrhosis by reducing hepatic myofibroblasts and modulating molecular profibrotic pathways.Jan 31, 2019

Pubmed Data : Hepatol Res. 2019 Feb ;49(2):212-223. Epub 2018 Nov 19. PMID: 30338893
Article Published Date : Jan 31, 2019
Study Type : Animal Study
Additional Links
Substances : Stevia
Diseases : Liver Cirrhosis, Liver Disease
Pharmacological Actions : Hepatoprotective, Matrix Metalloproteinase-13 (MMP-13) Inhibitor, Matrix metalloproteinase-2 (MMP-2) inhibitor, Transforming growth factor beta (TGF-β) inhibitor
[+]

Sulforaphane protects liver injury induced by intestinal ischemia in an animal model. Jun 28, 2010

Pubmed Data : World J Gastroenterol. 2010 Jun 28;16(24):3002-10. PMID: 20572303
Article Published Date : Jun 28, 2010
Study Type : Animal Study
Additional Links
Substances : Sulforaphane
Diseases : Intestinal Diseases, Liver Disease
Pharmacological Actions : Anticarcinogenic Agents, Antioxidants
[+]

Suppression of MT1 and melatonin treatment improves liver phenotypes in Mdr2 -/- miceApr 30, 2022

Pubmed Data : FASEB J. 2022 May ;36 Suppl 1. PMID: 35557275
Article Published Date : Apr 30, 2022
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Liver Disease
Pharmacological Actions : Hepatoprotective
[+]

Taurine may be used in combination with silymarin as an additional adjunct therapy to cure liver diseases such as fibrosis, cirrhosis and viral hepatitis.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(12):e0144509. Epub 2015 Dec 11. PMID: 26659465
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Silymarin, Taurine
Diseases : Chemically-Induced Liver Damage, Liver Cirrhosis, Liver Disease, Liver Fibrosis
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective
[+]

The compound found in Licorice known as glycyrrhizin accelerates liver regeneration and recovery from liver damaged in partially hepatectomized rats. Jan 28, 2008

Pubmed Data : Eur J Pharmacol. 2008 Jan 28;579(1-3):357-64. Epub 2007 Nov 1. PMID: 18022618
Article Published Date : Jan 28, 2008
Study Type : Animal Study
Additional Links
Substances : Licorice
Diseases : Liver Disease
Additional Keywords : Liver Regeneration, Regenerative Substances
[+]

Therapeutic potential of berberine in attenuating cholestatic liver injury.Jan 24, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Biosci. 2024 Jan 25 ;14(1):14. Epub 2024 Jan 25. PMID: 38273376
Article Published Date : Jan 24, 2024
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Cholangitis, Liver Disease
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Gastrointestinal Agents, Hepatoprotective
[+]

These findings suggest that thymoquinone, silymarin, and N-acetylcysteine have potential for the treatment of diseases causing liver injury.Jul 29, 2018

Pubmed Data : Biomed Pharmacother. 2018 Jul 30 ;106:1705-1712. Epub 2018 Jul 30. PMID: 30119245
Article Published Date : Jul 29, 2018
Study Type : Animal Study
Additional Links
Substances : Cysteine (see N-Acetylcysteine), Silymarin, Thymoquinone
Diseases : Liver Damage, Liver Disease
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective
[+]

These results raise concerns about the potential role of glyphosate in chronic liver disease and liver cancer risk.Dec 08, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Cancer. 2024 Dec 9. Epub 2024 Dec 9. PMID: 39653658
Article Published Date : Dec 08, 2024
Study Type : Animal Study
Additional Links
Diseases : Glyphosate Toxicity, Liver Cancer, Liver Disease
Problem Substances : Glyphosate
[+]

This proposes methoxyeugenol as a novel and potential therapeutic approach to treat chronic liver disease and fibrosis.Jul 15, 2021

Pubmed Data : J Ethnopharmacol. 2021 Jul 16 ;280:114433. Epub 2021 Jul 16. PMID: 34280502
Article Published Date : Jul 15, 2021
Study Type : Animal Study
Additional Links
Substances : Nutmeg, Propolis: Brazillian
Diseases : Liver Disease, Liver Fibrosis
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents
[+]

Vitamin D-enriched Shiitake mushroom exerts a synergistic anti-inflammatory effect in an immune-mediated hepatitis model.Mar 29, 2016

Pubmed Data : J Med Food. 2016 Mar 30. Epub 2016 Mar 30. PMID: 27027234
Article Published Date : Mar 29, 2016
Study Type : Animal Study
Additional Links
Substances : Shiitake Mushroom , Vitamin D
Diseases : Chemically-Induced Liver Damage, Hepatitis C, Liver Disease
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective
Additional Keywords : Natural Substance Synergy, Plant Extracts
Problem Substances : Concanavalin A
[+]

The effect of emodin on liver disease - comprehensive advances in molecular mechanisms.Sep 04, 2020

Pubmed Data : Eur J Pharmacol. 2020 Sep 5 ;882:173269. Epub 2020 Jun 14. PMID: 32553811
Article Published Date : Sep 04, 2020
Study Type : Review
Additional Links
Substances : Emodin
Diseases : Liver Cancer, Liver Damage, Liver Disease, Liver Fibrosis, Organ Transplantation: Liver
Pharmacological Actions : Anti-Fibrotic, Antioxidants, Apoptotic, Hepatoprotective, Hypolipidemic, Immunomodulatory, Transforming growth factor beta (TGF-β) inhibitor
[+]

A review of the hepataprotective effects of ginsenoside Rg1.Apr 16, 2017

Pubmed Data : J Ethnopharmacol. 2017 Apr 17. Epub 2017 Apr 17. PMID: 28427912
Article Published Date : Apr 16, 2017
Study Type : Review
Additional Links
Substances : Ginsenosides
Diseases : Liver Damage, Liver Disease
Pharmacological Actions : Hepatoprotective
Additional Keywords : Ginsenosides, Hepatoprotective, liver damage, Liver Disease
[+]

A review of the hepatoprotective effect of kaempferol.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Adv Pharmacol Pharm Sci. 2023 ;2023:1387665. Epub 2023 Feb 27. PMID: 36891541
Article Published Date : Dec 31, 2022
Study Type : Review
Additional Links
Substances : Kaempferol
Diseases : Acetaminophen (Tylenol) Toxicity , Liver Damage, Liver Disease
Pharmacological Actions : Hepatoprotective
Problem Substances : Acetaminophen
[+]

An overview of coenzyme Q10 and degenerative disorders affecting longevity.Feb 15, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2019 Feb 16 ;8(2). Epub 2019 Feb 16. PMID: 30781472
Article Published Date : Feb 15, 2019
Study Type : Review
Additional Links
Substances : Coenzyme Q10
Diseases : Cardiovascular Diseases, Diabetes Mellitus: Type 2, Kidney Diseases, Liver Disease
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Hypoglycemic Agents, Renoprotective
[+]

Astaxanthin in liver health and disease: a potential therapeutic agent.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Des Devel Ther. 2020 ;14:2275-2285. Epub 2020 Jun 9. PMID: 32606597
Article Published Date : Dec 31, 2019
Study Type : Review
Additional Links
Substances : Astaxanthin
Diseases : Liver Cancer, Liver Disease, Liver Fibrosis, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective
[+]

Bisphenol A is a carcinogen that induces lipid accumulation, peroxisome proliferator‑activated receptor‑γ expression and liver disease.Nov 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2022 Dec ;24(6):735. Epub 2022 Oct 31. PMID: 36466761
Article Published Date : Nov 30, 2022
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity, Liver Disease
Problem Substances : Bisphenol A
Adverse Pharmacological Actions : Carcinogenic
[+]

Cirsium japonicum might be a preventative treatment of NAFLD.Jun 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2014 Jul ;8(1):79-84. Epub 2014 Apr 25. PMID: 24944601
Article Published Date : Jun 30, 2014
Study Type : In Vitro Study
Additional Links
Substances : Thistle
Diseases : Liver Disease, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Hepatoprotective
Additional Keywords : Plant Extracts
[+]

Cocoa flavonoids may prevent oxidative-stress-induced damage to the liver.Mar 01, 2010

Pubmed Data : J Nutr Biochem. 2010 Mar;21(3):196-205. Epub 2009 Feb 5. PMID: 19195869
Article Published Date : Mar 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Liver Disease, Oxidative Stress
Pharmacological Actions : Antioxidants, Apoptotic, Hepatoprotective
Additional Keywords : Plant Extracts
[+]

Curcumin as a therapeutic strategy in liver diseases.Oct 16, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2019 Oct 17 ;11(10). Epub 2019 Oct 17. PMID: 31627369
Article Published Date : Oct 16, 2019
Study Type : Review
Additional Links
Substances : Curcumin
Diseases : Liver Disease, Liver Failure: Acute, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Antioxidants, Hepatoprotective
[+]

Cyanidin-3-glucoside enhances mitochondrial function and biogenesis in a human hepatocyte cell line.Nov 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cytotechnology. 2018 Dec ;70(6):1519-1528. Epub 2018 Aug 28. PMID: 30155610
Article Published Date : Nov 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Cyanidin 3-glucoside
Diseases : Liver Damage, Liver Disease, Mitochondrial Dysfunction
Pharmacological Actions : Hepatoprotective
[+]

Fucoidan: Biological Activity in Liver Diseases Nov 04, 2020

Pubmed Data : Am J Chin Med. 2020 Nov 5:1-16. Epub 2020 Nov 5. PMID: 33148007
Article Published Date : Nov 04, 2020
Study Type : Review
Additional Links
Substances : Fucoidan
Diseases : Ischemia, Liver Cancer, Liver Damage: Drug-Induced, Liver Disease, Liver Fibrosis, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Hepatoprotective
Additional Keywords : Polysaccharides
[+]

Glycyrrhiza glabra: a comprehensive review on its phytochemistry, biological activities, clinical evidence and toxicology.Dec 13, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Plants (Basel). 2021 Dec 14 ;10(12). Epub 2021 Dec 14. PMID: 34961221
Article Published Date : Dec 13, 2021
Study Type : Review
Additional Links
Substances : Licorice
Diseases : Cancers: All, Cardiovascular Diseases, Liver Damage, Liver Disease
Pharmacological Actions : Anti-Bacterial Agents, Cardioprotective, Hepatoprotective
[+]

Hepatoprotective activity of aqueous-methanol extract of Artemisia vulgaris.Jan 31, 2005

Pubmed Data : Phytother Res. 2005 Feb ;19(2):170-2. PMID: 15852491
Article Published Date : Jan 31, 2005
Study Type : In Vitro Study
Additional Links
Substances : Mugwort
Diseases : Lipopolysaccharide-Induced Toxicity, Liver Damage, Liver Disease
Pharmacological Actions : Hepatoprotective
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Hepatoprotective effects of diosmin: a narrative review. Aug 20, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2024 Aug 21. Epub 2024 Aug 21. PMID: 39167171
Article Published Date : Aug 20, 2024
Study Type : Review
Additional Links
Substances : Diosmin
Diseases : Alcoholic Liver Disease, Liver Damage, Liver Disease, Liver Injury: Ischemia/reperfusion
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Hyperoside as a potential natural product targeting oxidative stress in liver diseases.Jul 24, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2022 Jul 25 ;11(8). Epub 2022 Jul 25. PMID: 35892639
Article Published Date : Jul 24, 2022
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Liver Disease, Oxidative Stress
Pharmacological Actions : Antioxidants, Hepatoprotective
[+]

In a pooled analysis of trials in patients with cirrhosis, silymarin treatment was associated with a significant reduction in liver-related deaths.Feb 17, 2020

Pubmed Data : Adv Ther. 2020 Feb 17. Epub 2020 Feb 17. PMID: 32065376
Article Published Date : Feb 17, 2020
Study Type : Review
Additional Links
Substances : Milk Thistle, Silymarin
Diseases : Liver Disease
Pharmacological Actions : Hepatoprotective, Regenerative
Additional Keywords : Liver Regeneration
[+]

Indole-3-carbinol and its major derivatives: Their pharmacokinetics and important roles in hepatic protection.Dec 31, 2015

Pubmed Data : Curr Drug Metab. 2016 ;17(4):401-9. PMID: 26651978
Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Indole-3-Carbinol
Diseases : Liver Damage, Liver Disease, Liver Fibrosis, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Anti-Fibrotic, Hepatoprotective
[+]

Mangiferin for the management of liver diseases.Jun 22, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Foods. 2023 Jun 23 ;12(13). Epub 2023 Jun 23. PMID: 37444207
Article Published Date : Jun 22, 2023
Study Type : Review
Additional Links
Substances : Mangiferin
Diseases : Liver Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective
[+]

MASLD and aspartame: are new studies in the horizon? Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Med (Lausanne). 2023 ;10:1266918. Epub 2023 Dec 8. PMID: 38143439
Article Published Date : Dec 31, 2022
Study Type : Review
Additional Links
Diseases : Inflammation, Liver Disease
Problem Substances : Aspartame
[+]

Mesenchymal stem cell therapies for liver cirrhosis: MSCs as "conducting cells" for improvement of liver fibrosis and regeneration.Jan 01, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Inflamm Regen. 2019 ;39:18. Epub 2019 Sep 9. PMID: 31516638
Article Published Date : Jan 01, 2019
Study Type : Review
Additional Links
Diseases : Liver Cirrhosis, Liver Cirrhosis: Alcoholic , Liver Damage, Liver Disease
Therapeutic Actions : Stem Cell Related Therapy
Additional Keywords : Liver Regeneration
[+]

Molecular updates on berberine in liver diseases: Bench to bedside.May 30, 2021

Pubmed Data : Phytother Res. 2021 May 31. Epub 2021 May 31. PMID: 34056769
Article Published Date : May 30, 2021
Study Type : Review
Additional Links
Substances : Berberine
Diseases : Liver Disease
Pharmacological Actions : Hepatoprotective
[+]

Natural products in licorice for the therapy of liver diseases.Dec 31, 2018

Pubmed Data : Pharmacol Res. 2019 06 ;144:210-226. Epub 2019 Apr 22. PMID: 31022523
Article Published Date : Dec 31, 2018
Study Type : Review
Additional Links
Substances : Licorice
Diseases : Liver Disease
Pharmacological Actions : Hepatoprotective
[+]

Need for serological tests to exclude celiac disease when TSH and CK values non-indicative.Jul 18, 2007

Pubmed Data : MMW Fortschr Med. 2007 Jul 19 ;149(29-30):44-8; quiz 49. PMID: 17703692
Article Published Date : Jul 18, 2007
Study Type : Review
Additional Links
Diseases : Celiac Disease: Diagnostic Considerations, Hepatitis, Liver Disease
[+]

Nobiletin from citrus peel: a promising therapeutic agent for liver disease-pharmacological characteristics, mechanisms, and potential applications.Dec 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2024 ;15:1354809. Epub 2024 Feb 29. PMID: 38487166
Article Published Date : Dec 31, 2023
Study Type : Review
Additional Links
Substances : Nobiletin
Diseases : Liver Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective
[+]

Oligo-fucoidan enhances the immune system and protects hepatocytes.Jun 11, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomolecules. 2020 Jun 12 ;10(6). Epub 2020 Jun 12. PMID: 32545625
Article Published Date : Jun 11, 2020
Study Type : In Vitro Study
Additional Links
Substances : Fucoidan
Diseases : Liver Disease
Pharmacological Actions : Antiviral Agents, Immunomodulatory
[+]

Pachypodol isolated from P. cablin can protect hepatocytes from oxidative injury.Aug 20, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Aug 21 ;20(17). Epub 2019 Aug 21. PMID: 31438541
Article Published Date : Aug 20, 2019
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids, Quercetin
Diseases : Liver Disease, Oxidative Stress
Pharmacological Actions : Antioxidants, Hepatoprotective, Nrf2 activation
[+]

Paeoniflorin is a natural product with multiple targets in liver diseases.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2020 ;11:531. Epub 2020 Apr 28. PMID: 32410996
Article Published Date : Dec 31, 2019
Study Type : Review
Additional Links
Substances : Paeoniflorin
Diseases : Liver Cancer, Liver Disease, Liver Fibrosis
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Anti-metastatic, Antioxidants, Apoptotic, Hepatoprotective, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Immunomodulatory, NF-kappaB Inhibitor, Nrf2 activation, Transforming growth factor beta (TGF-β) inhibitor
[+]

Patients with NASH was observed have a distinct gut microbiota when compared to control groups.Sep 04, 2017

Pubmed Data : Eur J Nutr. 2017 Sep 5. Epub 2017 Sep 5. PMID: 28875318
Article Published Date : Sep 04, 2017
Study Type : Review
Additional Links
Diseases : Liver Disease, Nonalcoholic fatty liver disease (NAFLD)
Additional Keywords : Microbiota
[+]

Pharmacological properties of baicalin on liver diseases: a narrative review.Sep 30, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacol Rep. 2021 Oct ;73(5):1230-1239. Epub 2021 Feb 17. PMID: 33595821
Article Published Date : Sep 30, 2021
Study Type : Review
Additional Links
Substances : Flavonoids
Diseases : Liver Disease
Pharmacological Actions : Hepatoprotective
[+]

Photobiomodulation with red light-emitting diodes accelerates hepatocyte proliferation.Sep 30, 2018

Pubmed Data : Hepatol Res. 2018 Oct ;48(11):926-936. Epub 2018 Jul 1. PMID: 29710411
Article Published Date : Sep 30, 2018
Study Type : In Vitro Study
Additional Links
Diseases : Liver Disease, Organ Transplantation: Liver
Therapeutic Actions : Light Therapy: Red Colored, Photobiomodulation
Pharmacological Actions : Proliferative
Additional Keywords : Liver Regeneration
[+]

Preventive and therapeutic role of Tanshinone ⅡA in hepatology.Mar 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Apr ;112:108676. Epub 2019 Feb 21. PMID: 30797157
Article Published Date : Mar 31, 2019
Study Type : Review
Additional Links
Substances : Tanshinone IIA
Diseases : Fatty Liver, Liver Cancer, Liver Damage, Liver Disease, Liver Fibrosis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Chemotherapeutic, Hepatoprotective
[+]

Probiotics have demonstrated some benefit in several specific gastrointestinal and liver diseases.Dec 31, 2018

Pubmed Data : Endocr Metab Immune Disord Drug Targets. 2019 ;19(5):549-570. PMID: 30360751
Article Published Date : Dec 31, 2018
Study Type : Review
Additional Links
Substances : Probiotics
Diseases : Gastrointestinal Diseases, Liver Disease
Pharmacological Actions : Gastrointestinal Agents
[+]

Quercetin protects human liver cells from ethanol-induced oxidative stress. Aug 01, 2007

Pubmed Data : J Hepatol. 2007 Aug;47(2):253-61. Epub 2007 Mar 7. PMID: 17433488
Article Published Date : Aug 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Quercetin
Diseases : Liver Disease, Oxidative Stress
Pharmacological Actions : Hepatoprotective
[+]

Resveratrol may have therapeutic value in liver disease. Sep 01, 2010

Pubmed Data : Liver Int. 2010 Sep;30(8):1103-14. Epub 2010 Jun 14. PMID: 20557453
Article Published Date : Sep 01, 2010
Study Type : Review
Additional Links
Substances : Resveratrol
Diseases : Acetaminophen (Tylenol) Toxicity , Alcohol Toxicity , Liver Disease
Pharmacological Actions : Antioxidants, Hepatoprotective, NF-kappaB Inhibitor
Additional Keywords : Stilbenes
[+]

Review: Drug-induced liver injury associated with statins.Nov 01, 2009

Pubmed Data : Semin Liver Dis. 2009 Nov ;29(4):412-22. Epub 2009 Oct 13. PMID: 19826975
Article Published Date : Nov 01, 2009
Study Type : Review
Additional Links
Diseases : Chemically-Induced Liver Damage, Hepatitis: Autoimmune , Hepatitis: Cholestatic, Liver Damage, Liver Disease, Statin-Induced Pathologies
Problem Substances : Atorvastatin, Statin Drugs
Adverse Pharmacological Actions : Hepatotoxic
[+]

Rosmarinic acid stimulates liver regeneration through the mTOR pathway.Nov 30, 2016

Pubmed Data : Phytomedicine. 2016 Dec 1 ;23(13):1574-1582. Epub 2016 Sep 30. PMID: 27823621
Article Published Date : Nov 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Rosemaric Acid
Diseases : Liver Disease
Pharmacological Actions : mTOR/S6K pathway Activator
Additional Keywords : Regenerative Substances
[+]

The endocannabinoid system may play an important role in liver diseases.Oct 07, 2010

Pubmed Data : Dig Liver Dis. 2010 Oct 7. Epub 2010 Oct 7. PMID: 20934397
Article Published Date : Oct 07, 2010
Study Type : Commentary
Additional Links
Diseases : Endocannabinoid System, Liver Disease
[+]

The impact of proton pump inhibitors in liver diseases and the effects on the liver.Mar 30, 2022

Pubmed Data : J Dig Dis. 2022 Mar 31. Epub 2022 Mar 31. PMID: 35357775
Article Published Date : Mar 30, 2022
Study Type : Review
Additional Links
Diseases : Liver Disease
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

The information presented in this paper identifies curcumin as a promising renoprotective molecule against renal injury. Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Redox Biol. 2013 ;1:448-56. Epub 2013 Sep 17. PMID: 24191240
Article Published Date : Dec 31, 2012
Study Type : Review
Additional Links
Substances : Curcumin
Diseases : Liver Damage, Liver Damage: Drug-Induced, Liver Disease, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Chemoprotective Agents, Renoprotective
[+]

The mechanisms by which N. sativa impede progression in chronic liver diseases should be used as a preventive medicine in patients with hepatic disorders.Dec 31, 2017

Pubmed Data : Curr Pharm Biotechnol. 2018 ;19(1):43-67. PMID: 29701149
Article Published Date : Dec 31, 2017
Study Type : Review
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Lipid Peroxidation, Liver Damage, Liver Disease
Pharmacological Actions : Antioxidants, Hepatoprotective, Superoxide Dismutase Up-regulation
Additional Keywords : Plant Extracts
[+]

The therapeutic effects of Portulaca oleracea L. in hepatogastric disorders.Jan 31, 2019

Pubmed Data : Gastroenterol Hepatol. 2019 Feb ;42(2):127-132. Epub 2018 Oct 13. PMID: 30327154
Article Published Date : Jan 31, 2019
Study Type : Review
Additional Links
Substances : Purslane
Diseases : Gastrointestinal Complaints, Liver Disease
Pharmacological Actions : Gastroprotective, Hepatoprotective
[+]

Therapeutic potential of sulforaphane in liver diseases.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2023 ;14:1256029. Epub 2023 Aug 29. PMID: 37705537
Article Published Date : Dec 31, 2022
Study Type : Review
Additional Links
Substances : Sulforaphane
Diseases : Liver Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective
[+]

This paper summarizes the current knowledge on the beneficial effects of Korean red ginseng on chronic liver disease.Sep 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ginseng Res. 2017 Oct ;41(4):450-455. Epub 2017 Jan 5. PMID: 29021690
Article Published Date : Sep 30, 2017
Study Type : Review
Additional Links
Substances : Ginseng (Korean)
Diseases : Hepatitis C, Liver Cancer, Liver Disease, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Antioxidants, Hepatoprotective
[+]

This review article aims to present different aspects of Silybum marianum, especially the data in recently published articles about its effects on different diseases.Sep 30, 2015

Pubmed Data : J Evid Based Complementary Altern Med. 2015 Oct ;20(4):292-301. Epub 2015 Feb 16. PMID: 25686616
Article Published Date : Sep 30, 2015
Study Type : Review
Additional Links
Substances : Milk Thistle
Diseases : Alzheimer's Disease, Cancers: All, Insulin Resistance, Liver Cirrhosis, Liver Disease
Pharmacological Actions : Anti-atherogenic, Antioxidants, Cardiovascular Agents, Hepatoprotective, Hypolipidemic, Regenerative
[+]

This reviews the potential roles of melatonin in liver injuries and diseases, paying special attention to the mechanisms of action.Mar 22, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2017 Mar 23 ;18(4). Epub 2017 Mar 23. PMID: 28333073
Article Published Date : Mar 22, 2017
Study Type : Review
Additional Links
Substances : Melatonin
Diseases : Liver Damage, Liver Disease
Pharmacological Actions : Hepatoprotective
[+]

Two purified proteins from royal jelly with in vitro dual anti-hepatic damage potency.Jan 31, 2019

Pubmed Data : Int J Biol Macromol. 2019 Feb 1 ;128:782-795. Epub 2019 Feb 1. PMID: 30711561
Article Published Date : Jan 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Royal Jelly
Diseases : Liver Disease
Pharmacological Actions : Hepatoprotective
[+]

Withaferin A in the treatment of liver diseases: progress and pharmacokinetic insights.Dec 12, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Metab Dispos. 2021 Dec 13. Epub 2021 Dec 13. PMID: 34903587
Article Published Date : Dec 12, 2021
Study Type : Review
Additional Links
Substances : Ashwagandha
Diseases : Liver Disease
Pharmacological Actions : Hepatoprotective

Copyright: blueringmedia / 123RF Stock Photo

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