Leukemia: Chronic Lymphocytic Leukemia (CLL)

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40 Substances Researched for Leukemia: Chronic Lymphocytic Leukemia (CLL)
NameACCKFocus
Curcumin514Locked
Citral110Locked
Mistletoe110Locked
Oleocanthal110Locked
Olive leaf extract110Locked
Rice Bran110Locked
Verbena officinalis110Locked
Deguelin26Locked
EGCG (Epigallocatechin gallate)45Locked
Neem15Locked
Quercetin45Locked
Berberine44Locked
Beet13Locked
Carrot13Locked
Honokiol23Locked
Resveratrol33Locked
Vitamin D23Locked
Genistein12Locked
St. Johns Wort22Locked
Wogonin12Locked
cottonseed oil (gossypol)12Locked
Allicin11Locked
Bilberry11Locked
Carbon 6011Locked
Catechin 11Locked
Chaga Mushroom (Inonotus obliquus)11Locked
Fisetin11Locked
Gamma-Linoleic Acid (GLA) 11Locked
Garlic11Locked
Green Tea21Locked
Hops11Locked
Hyperforin11Locked
Indole-3-Carbinol11Locked
Luteolin11Locked
Mango 11Locked
Omega-3 Fatty Acids11Locked
Polyphenols11Locked
Tripterygium wilfordii11Locked
Triptolide11Locked
Vitamin C11Locked
3 Problem Substances Researched for Leukemia: Chronic Lymphocytic Leukemia (CLL)
NameACCKFocus
Radon110Locked
Tylenol110Locked
Hepatitis Viruses11Locked
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View the Evidence:
54 Abstracts with Leukemia: Chronic Lymphocytic Leukemia (CLL) Research

[+]

Ultra-processed food consumption and cancer risk.May 31, 2023

Pubmed Data : Clin Nutr. 2023 Jun ;42(6):919-928. Epub 2023 Mar 30. PMID: 37087831
Article Published Date : May 31, 2023
Study Type : Meta Analysis, Review
Additional Links
Diseases : Colorectal Cancer, Leukemia: Chronic Lymphocytic Leukemia (CLL), Pancreatic Cancer
Additional Keywords : Ultra-Processed Food
[+]

Chronic tylenol use is associated wtih an almost two-fold increased risk of blood cancer.May 09, 2011

Pubmed Data : J Clin Oncol. 2011 May 9. Epub 2011 May 9. PMID: 21555699
Article Published Date : May 09, 2011
Study Type : Human Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity , Leukemia: Chronic Lymphocytic Leukemia (CLL), Lymphoma
Problem Substances : Tylenol
Adverse Pharmacological Actions : Carcinogenic
[+]

Each 10% increment in the consumption of UPF was associated with a 22% higher odds ratio of chronic lymphocytic leukemia.May 19, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2021 May 20 ;18(10). Epub 2021 May 20. PMID: 34065213
Article Published Date : May 19, 2021
Study Type : Human Study
Additional Links
Diseases : Leukemia: Chronic Lymphocytic Leukemia (CLL)
Additional Keywords : Increased Risk, Ultra-Processed Food
[+]

Incidence rates for chronic lymphocytic leukemia in the US states are significantly correlated with the levels of residential radon.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Future Oncol. 2016 Jan ;12(2):165-74. Epub 2015 Oct 30. PMID: 26515766
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Diseases : Chronic Lymphocytic Leukemia
Additional Keywords : Risk Factors
Problem Substances : Radon
[+]

Integrative analysis of spontaneous CLL regression highlights genetic and microenvironmental interdependency in CLL.Jan 05, 2020

Pubmed Data : Blood. 2020 02 6 ;135(6):411-428. PMID: 31794600
Article Published Date : Jan 05, 2020
Study Type : Human Study
Additional Links
Diseases : Leukemia: Chronic Lymphocytic Leukemia (CLL)
Additional Keywords : Spontaneous Tumor Regression
[+]

Mistletoe extract is known to induce apoptosis and immunactivation in chronic lymphocytic leukemia, and has been shown to have a non-propogating effect on leukemic cells.Nov 01, 2007

Pubmed Data : Anticancer Res. 2007 Nov-Dec;27(6B):4195-200. PMID: 18225591
Article Published Date : Nov 01, 2007
Study Type : Human Study
Additional Links
Substances : Mistletoe
Diseases : Leukemia: Chronic Lymphocytic Leukemia (CLL)
Pharmacological Actions : Apoptotic
Additional Keywords : Plant Extracts
[+]

Rice bran arabinoxylan and curcumin therapy may be of benefit to patients with early-stage B-cell lymphoid malignancies.May 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Integr Cancer Ther. 2016 Jun ;15(2):183-9. Epub 2016 May 6. PMID: 27154182
Article Published Date : May 31, 2016
Study Type : Human Study
Additional Links
Substances : Curcumin, Rice Bran
Diseases : Leukemia: B-Cell, Leukemia: Chronic Lymphocytic Leukemia (CLL), Smoldering multiple myeloma (SMM)
Pharmacological Actions : Anti-Inflammatory Agents
[+]

The effect of dietary intervention with high-oleocanthal and oleacein olive oil in Patients with early-stage chronic lymphocytic leukemia.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Oncol. 2021 ;11:810249. Epub 2022 Jan 21. PMID: 35127522
Article Published Date : Dec 31, 2020
Study Type : Human Study
Additional Links
Substances : Oleocanthal, Olive leaf extract
Diseases : Chronic Lymphocytic Leukemia
Pharmacological Actions : Apoptotic, Chemotherapeutic
[+]

Verbena officinalis essential oil and its component citral has apoptoic-inducing activity against chronic lymphocytic leukemia.Oct 01, 2009

Pubmed Data : Int J Immunopathol Pharmacol. 2009 Oct-Dec;22(4):1097-104. PMID: 20074474
Article Published Date : Oct 01, 2009
Study Type : Human Study
Additional Links
Substances : Citral, Verbena officinalis
Diseases : Leukemia: Chronic Lymphocytic Leukemia (CLL)
Pharmacological Actions : Apoptotic, Tumor Suppressor Protein p53 Upregulation
[+]

Neem leaf extract exhibits anti-leukemic properties in patient primary chronic lymphocytic leukemia cells.Feb 28, 2014

Pubmed Data : Leuk Lymphoma. 2014 Mar ;55(3):652-61. Epub 2013 Jul 1. PMID: 23721511
Article Published Date : Feb 28, 2014
Study Type : Human In Vitro
Additional Links
Substances : Neem
Diseases : Leukemia: Chronic Lymphocytic Leukemia (CLL)
Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Dose Response, Plant Extracts
[+]

These results suggest deguelin could have potential for the treatment of human CLL.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2016 ;11(4):e0154159. Epub 2016 Apr 21. PMID: 27101369
Article Published Date : Dec 31, 2015
Study Type : Animal Study, Human In Vitro
Additional Links
Substances : Deguelin
Diseases : Chronic Lymphocytic Leukemia
Pharmacological Actions : Apoptotic, NF-kappaB Inhibitor
Additional Keywords : Natural Substance/Drug Synergy
[+]

A case of complete and durable molecular remission of chronic lymphocytic leukemia following treatment with epigallocatechin-3-gallate.Dec 31, 2014

Pubmed Data : Cureus. 2015 ;7(12):e441. Epub 2015 Dec 29. PMID: 26858922
Article Published Date : Dec 31, 2014
Study Type : Human: Case Report
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Chronic Lymphocytic Leukemia
Pharmacological Actions : Chemopreventive
Additional Keywords : Cancer Remission, Significant Treatment Outcome
[+]

Beetroot-carrot juice can be used as an effective treatment for CLL alone or in combination with chlorambucil.Jun 14, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Open Access Maced J Med Sci. 2015 Jun 15 ;3(2):331-6. Epub 2015 Jun 2. PMID: 27275246
Article Published Date : Jun 14, 2015
Study Type : Human: Case Report
Additional Links
Substances : Beet, Carrot
Diseases : Leukemia: Chronic Lymphocytic Leukemia (CLL)
Pharmacological Actions : Chemopreventive, Chemotherapeutic
Additional Keywords : Natural Substance/Drug Synergy
[+]

"Dietary polyphenols in cancer prevention: the example of the flavonoid quercetin in leukemia."Jun 30, 2012

Pubmed Data : Ann N Y Acad Sci. 2012 Jul ;1259:95-103. PMID: 22758641
Article Published Date : Jun 30, 2012
Study Type : Insect Study
Additional Links
Substances : Quercetin
Diseases : Chronic Lymphocytic Leukemia, Leukemia
Pharmacological Actions : Chemosensitizer
[+]

Genistein increases the efficacy of fludarabine in inducing cell death in blood cells from CLL and PLL patients. Apr 01, 2007

Pubmed Data : Cancer Immunol Immunother. 2007 Apr;56(4):501-14. Epub 2006 Oct 19. PMID: 17051411
Article Published Date : Apr 01, 2007
Study Type : Animal Study
Additional Links
Substances : Genistein
Diseases : B-cell prolymphocytic leukemia (B-PLL), Leukemia: B-Cell, Leukemia: Chronic Lymphocytic Leukemia (CLL)
Pharmacological Actions : Apoptotic, Chemosensitizer
[+]

Honokiol-chlorambucil co-prodrugs selectively enhance the killing effect through STAT3 binding on lymphocytic leukemia cells.Aug 10, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : ACS Omega. 2020 Aug 11 ;5(31):19844-19852. Epub 2020 Jul 29. PMID: 32803080
Article Published Date : Aug 10, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Honokiol
Diseases : Chronic Lymphocytic Leukemia
Pharmacological Actions : Antiproliferative , STAT3 Inhibitor
[+]

Vanillic acid protects mortality and toxicity induced by N-ethyl-N-nitrosourea in mice.May 31, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxicol Rep. 2024 Jun ;12:389-396. Epub 2024 Mar 28. PMID: 38590344
Article Published Date : May 31, 2024
Study Type : Animal Study
Additional Links
Substances : Vanillic Acid
Diseases : Chronic Lymphocytic Leukemia
Pharmacological Actions : Antioxidants, Chemopreventive
[+]

Vitamin D and gossypol appear to reduce lymphocyte content in Chronic Lymphocytic Leukemia.Aug 01, 2004

Pubmed Data : Leuk Res. 2004 Aug;28(8):851-61. PMID: 18573644
Article Published Date : Aug 01, 2004
Study Type : Animal Study
Additional Links
Substances : cottonseed oil (gossypol), Vitamin D
Diseases : Leukemia: Chronic Lymphocytic Leukemia (CLL)
[+]

Wogonin treatment prevented leukemia development when given early after transplantation.Jan 10, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Haematologica. 2018 Jan 11. Epub 2018 Jan 11. PMID: 29326123
Article Published Date : Jan 10, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Chronic Lymphocytic Leukemia
Pharmacological Actions : Anti-Inflammatory Agents, Chemotherapeutic
[+]

"Inhibition of Nuclear Factor Kappa B activation in Early-Stage Chronic Lymphocytic Leukemia by Omega-3 Fatty Acids."Nov 28, 2012

Pubmed Data : Cancer Invest. 2012 Nov 29. Epub 2012 Nov 29. PMID: 23193970
Article Published Date : Nov 28, 2012
Study Type : In Vitro Study
Additional Links
Substances : Omega-3 Fatty Acids
Diseases : Chronic Lymphocytic Leukemia
Pharmacological Actions : NF-kappaB Inhibitor
[+]

Allicin, a highly active component from freshly crushed garlic, induces programmed cell death in B-chronic lymphocytic leukemia tumor cells. Feb 01, 2005

Pubmed Data : Mol Cancer Ther. 2005 Feb;4(2):325-31. PMID: 15713903
Article Published Date : Feb 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Allicin, Garlic
Diseases : Leukemia: Chronic Lymphocytic Leukemia (CLL), Lymphoma: B-Cell, Lymphoma: Mantle Cell
Pharmacological Actions : Apoptotic
[+]

An anthocyanin-rich dietary bilberry extract induced a redox-sensitive apoptosis in CLL cells with little effect on healthy peripheral blood mononuclear cells.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2015 ;5:8996. Epub 2015 Mar 11. PMID: 25757575
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Bilberry
Diseases : Chronic Lymphocytic Leukemia
Pharmacological Actions : Apoptotic, Caspase-3 Activation, Chemotherapeutic
Additional Keywords : Plant Extracts, Selective Cytotoxicity
[+]

Anti-tumor effect of berberine on chronic lymphocytic leukemia cells.Sep 28, 2022

Pubmed Data : Med Oncol. 2022 Sep 29 ;39(12):217. Epub 2022 Sep 29. PMID: 36175700
Article Published Date : Sep 28, 2022
Study Type : In Vitro Study
Additional Links
Substances : Berberine
Diseases : Leukemia: Chronic Lymphocytic Leukemia (CLL)
Pharmacological Actions : Chemotherapeutic, MicroRNA modulator
[+]

Apoptotic effect of berberine via Bcl-2, ROR1, and mir-21 in patients with B-chronic lymphocytic leukemia.Nov 09, 2020

Pubmed Data : Phytother Res. 2020 Nov 10. Epub 2020 Nov 10. PMID: 33174291
Article Published Date : Nov 09, 2020
Study Type : In Vitro Study
Additional Links
Substances : Berberine
Diseases : Chronic Lymphocytic Leukemia
Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation, MicroRNA modulator
[+]

Ascorbic acid synergistically enhances the therapeutic effect of targeted therapy in chronic lymphocytic leukemia.Oct 27, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Exp Clin Cancer Res. 2020 Oct 28 ;39(1):228. Epub 2020 Oct 28. PMID: 33115525
Article Published Date : Oct 27, 2020
Study Type : In Vitro Study
Additional Links
Substances : Vitamin C
Diseases : Chronic Lymphocytic Leukemia
Pharmacological Actions : Apoptotic
[+]

Association of leukemia target genes Tet2, Bcl2, and Slc23a2 in vitamin C pathways.Aug 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Genomics Proteomics. 2019 Sep-Oct;16(5):333-344. PMID: 31467227
Article Published Date : Aug 31, 2019
Study Type : In Vitro Study
Additional Links
Diseases : Chronic Lymphocytic Leukemia, Promyelocytic leukemia
Pharmacological Actions : Chemotherapeutic
Additional Keywords : Gene Expression Regulation
[+]

Berberine affects mitochondrial activity and cell growth of leukemic cells from chronic lymphocytic leukemia patients.Oct 04, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2020 Oct 5 ;10(1):16519. Epub 2020 Oct 5. PMID: 33020573
Article Published Date : Oct 04, 2020
Study Type : In Vitro Study
Additional Links
Substances : Berberine
Diseases : Leukemia: Chronic Lymphocytic Leukemia (CLL)
Pharmacological Actions : Antiproliferative
[+]

Both fisetin and quercetin were able to augment the cytotoxic activity of luteolin against chronic lymphocytic leukemia cells. Aug 03, 2016

Pubmed Data : Food Funct. 2016 Aug 4. Epub 2016 Aug 4. PMID: 27489195
Article Published Date : Aug 03, 2016
Study Type : In Vitro Study
Additional Links
Substances : Fisetin, Luteolin, Quercetin
Diseases : Chronic Lymphocytic Leukemia
Pharmacological Actions : Apoptotic
Additional Keywords : Natural Substance Synergy
[+]

Compounds from chaga mushroom exhibited strong cytotoxicity against A549 tumor cell lines.Feb 28, 2015

Pubmed Data : Fitoterapia. 2015 Mar ;101:34-40. Epub 2014 Dec 24. PMID: 25542686
Article Published Date : Feb 28, 2015
Study Type : In Vitro Study
Additional Links
Substances : Chaga Mushroom (Inonotus obliquus)
Diseases : Cervical Cancer, Chronic Lymphocytic Leukemia, Colon Cancer, Lung Cancer
Pharmacological Actions : Antineoplastic Agents, Cytotoxic
[+]

Curcumin (from Turmeric) increases the efficacy of chemotherapeutic agents in the treatment of B-CLL.Jan 01, 2007

Pubmed Data : Am J Hematol. 2007 Jan;82(1):23-30 PMID: 16947318
Article Published Date : Jan 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Leukemia: Chronic Lymphocytic Leukemia (CLL)
Pharmacological Actions : Drug synergy
[+]

Curcumin induces apoptosis in primary resting B chronic lymphocytic leukemia cells.Apr 01, 2009

Pubmed Data : Leuk Lymphoma. 2009 Apr;50(4):625-32. PMID: 19373661
Article Published Date : Apr 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Leukemia: Chronic Lymphocytic Leukemia (CLL)
Pharmacological Actions : Antineoplastic Agents, Apoptotic
[+]

Curcumin induces programmed cell death in chronic lymphocytic leukemia B cells and works synergistically with the green tea polypenol EGCG. Jan 01, 1975

Pubmed Data : Clin Nephrol. 1975;3(5):195-203. PMID: 19228728
Article Published Date : Jan 01, 1975
Study Type : In Vitro Study
Additional Links
Substances : Curcumin, EGCG (Epigallocatechin gallate), Green Tea, Polyphenols
Diseases : Leukemia: Chronic Lymphocytic Leukemia (CLL)
Pharmacological Actions : Apoptotic
Additional Keywords : Natural Substance Synergy
[+]

Deguelin induces programmed cell death in B-cell chronic lymphocytic leukemia (B-CLL) cells.Aug 01, 2007

Pubmed Data : Leukemia. 2007 Aug;21(8):1610-8. Epub 2007 Jun 14. PMID: 17568818
Article Published Date : Aug 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Deguelin
Diseases : Leukemia: Chronic Lymphocytic Leukemia (CLL)
Pharmacological Actions : Antiproliferative , Apoptotic, NF-kappaB Inhibitor
[+]

Effects of berberine on leukemia with a focus on its molecular targets. Mar 23, 2022

Pubmed Data : Anticancer Agents Med Chem. 2022 Mar 24. Epub 2022 Mar 24. PMID: 35331097
Article Published Date : Mar 23, 2022
Study Type : Review
Additional Links
Substances : Berberine
Diseases : Acute Myeloid Leukemia, Chronic Lymphocytic Leukemia
Pharmacological Actions : Anti-Inflammatory Agents, Antiproliferative
[+]

Gamma-linolenic acid induces apoptosis in B-chronic lymphocytic leukaemia cells in vitro.Jan 01, 2001

Pubmed Data : Leuk Lymphoma. 2001 Jan;40(3-4):393-403. PMID: 11426562
Article Published Date : Jan 01, 2001
Study Type : In Vitro Study
Additional Links
Substances : Gamma-Linoleic Acid (GLA)
Diseases : Leukemia: Chronic Lymphocytic Leukemia (CLL)
Pharmacological Actions : Apoptotic
[+]

Green tea contains phytochemicals (e.g. EGCG) which exhibit significant therapeutic activity in Chronic Lymphocytic Leukemia.Aug 01, 2004

Pubmed Data : Blood. 2004 Aug 1;104(3):788-94. Epub 2004 Mar 2. PMID: 14996703
Article Published Date : Aug 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Leukemia: Chronic Lymphocytic Leukemia (CLL)
[+]

Hepatitis viruses may contribute to the pathogenesis of lymphoproliferative disorders. Aug 14, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Med Life. 2011 Aug 15 ;4(3):256-63. Epub 2011 Aug 25. PMID: 22567048
Article Published Date : Aug 14, 2011
Study Type : Review
Additional Links
Diseases : Chronic Lymphocytic Leukemia, Lymphoproliferative Disorders
Problem Substances : Hepatitis Viruses
[+]

Honokiol is a potent inducer of apoptosis in B-CLL cells.Jul 15, 2005

Pubmed Data : Blood. 2005 Jul 15;106(2):690-7. Epub 2005 Mar 31. PMID: 15802533
Article Published Date : Jul 15, 2005
Study Type : In Vitro Study
Additional Links
Substances : Honokiol
Diseases : Leukemia: B-Cell, Leukemia: Chronic Lymphocytic Leukemia (CLL)
Pharmacological Actions : Drug synergy
[+]

Hyperforin (a fat-soluble compound from St. John's wort) may improve B-cell Chronic Lymphocytic Leukemia. Sep 01, 2006

Pubmed Data : Leukemia. 2006 Sep;20(9):1519-25. Epub 2006 Jun 22. PMID: 16791262
Article Published Date : Sep 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : St. Johns Wort
Diseases : Leukemia: B-Cell, Leukemia: Chronic Lymphocytic Leukemia (CLL)
Additional Keywords : Hyperforin
[+]

Hyperforin induces apoptosis of chronic lymphocytic leukemia cells. Dec 31, 2011

Pubmed Data : Int J Oncol. 2012 Jan ;40(1):269-76. Epub 2011 Sep 22. PMID: 21947285
Article Published Date : Dec 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Hyperforin
Diseases : Chronic Lymphocytic Leukemia
Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation
[+]

Hyperforin, a compound found with St. Johns wort, have anticancer activity against leukemic cells from patients with B-cell CLL. Mar 01, 2006

Pubmed Data : Leukemia. 2006 Mar;20(3):491-7. PMID: 16424868
Article Published Date : Mar 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : St. Johns Wort
Diseases : Leukemia: Chronic Lymphocytic Leukemia (CLL)
Pharmacological Actions : Apoptotic
[+]

Indole-3-carbinol synergizes with and restores fludarabine sensitivity in chronic lymphocytic leukemia cells .Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Cancer Res. 2016 Jan 1 ;22(1):134-45. Epub 2015 Aug 31. PMID: 26324744
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Indole-3-Carbinol
Diseases : Chronic Lymphocytic Leukemia
Pharmacological Actions : Antineoplastic Agents, Apoptotic, Chemosensitizer, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Natural Substance/Drug Synergy
[+]

Mangifera Indica can act promising source for anti-cancer treatment candidate.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Pharm Res. 2019 ;18(4):1843-1853. PMID: 32184851
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Mango
Diseases : Leukemia: Chronic Lymphocytic Leukemia (CLL)
Pharmacological Actions : Cytotoxic
[+]

Photocytotoxic effect of C60 fullerene against L1210 leukemic cells is accompanied by enhanced nitric oxide production and p38 MAPK activation.May 31, 2016

Pubmed Data : Exp Oncol. 2016 Jun ;38(2):89-93. PMID: 27356576
Article Published Date : May 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Carbon 60
Diseases : Chronic Lymphocytic Leukemia
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Cell cycle arrest
[+]

Quercetin may overcome chemotherapy-resistance in chronic lymphocytic leukemia patients.Aug 24, 2010

Pubmed Data : Br J Cancer. 2010 Aug 24;103(5):642-8. Epub 2010 Jul 20. PMID: 20648016
Article Published Date : Aug 24, 2010
Study Type : In Vitro Study
Additional Links
Substances : Quercetin
Diseases : Leukemia: Chronic Lymphocytic Leukemia (CLL)
Pharmacological Actions : Apoptotic, Chemosensitizer
Additional Keywords : Drug-Plant-Vitamin Synergies
[+]

Resveratrol induces apoptosis in malignant lymphocytes of chronic lymphocytic leukemia through DNA damage.Aug 17, 2010

Pubmed Data : Ann Hematol. 2010 Aug 17. Epub 2010 Aug 17. PMID: 20714724
Article Published Date : Aug 17, 2010
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Chronic Lymphocytic Leukemia
Pharmacological Actions : Apoptotic
[+]

Resveratrol induces programmed cell death in human B-cell chronic lymphocytic leukemia cell lines. Jun 01, 2002

Pubmed Data : Br J Haematol. 2002 Jun;117(4):842-51. PMID: 12060119
Article Published Date : Jun 01, 2002
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Leukemia: B-Cell, Leukemia: Chronic Lymphocytic Leukemia (CLL)
Pharmacological Actions : Apoptotic
[+]

Resveratrol induces programmed cell death in leukemic B-cells. Aug 01, 2004

Pubmed Data : Leuk Res. 2004 Aug;28(8):851-61. PMID: 15203283
Article Published Date : Aug 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Leukemia: B-Cell, Leukemia: Chronic Lymphocytic Leukemia (CLL)
Pharmacological Actions : Apoptotic
[+]

The pleotropic activity of quercetin in chronic lymphocytic leukemia is obtained by the direct inhibition of key protein kinases.Sep 30, 2014

Pubmed Data : Food Funct. 2014 Oct ;5(10):2393-401. Epub 2014 Aug 6. PMID: 25096193
Article Published Date : Sep 30, 2014
Study Type : Review
Additional Links
Substances : Quercetin
Diseases : Chronic Lymphocytic Leukemia, Leukemia
Pharmacological Actions : Antineoplastic Agents, Apoptotic, Chemosensitizer
Additional Keywords : Natural Substance/Drug Synergy
[+]

These results indicate a relevant biological role for vitamin D in chronic lymphocytic leukemia pathophysiology.Jan 13, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancers (Basel). 2021 Jan 14 ;13(2). Epub 2021 Jan 14. PMID: 33466695
Article Published Date : Jan 13, 2021
Study Type : In Vitro Study
Additional Links
Substances : Vitamin D
Diseases : Chronic Lymphocytic Leukemia
Pharmacological Actions : Immunomodulatory
[+]

Triptolide inhibits transcription factor NF-kappa B, which translates into a therapeutic effect against various leukemias, multiple myeloma and myelodysplastic syndrome.Jul 02, 2010

Pubmed Data : Curr Mol Pharmacol. 2010 Jul 2. Epub 2010 Jul 2. PMID: 20594187
Article Published Date : Jul 02, 2010
Study Type : In Vitro Study
Additional Links
Substances : Tripterygium wilfordii, Triptolide
Diseases : Leukemia, Leukemia: Acute myelogenous leukemia (AML) , Leukemia: Chronic Lymphocytic Leukemia (CLL), Leukemia: Chronic myelogenous leukemia (CML) , Multiple Myeloma, Myelodysplastic Syndrome
Pharmacological Actions : Chemosensitizer, NF-kappaB Inhibitor
[+]

Turmeric and green tea have significant apoptic effects in chronic lymphocytic leukemia.Feb 15, 2009

Pubmed Data : Clin Cancer Res. 2009 Feb 15;15(4):1123-5. PMID: 19228716
Article Published Date : Feb 15, 2009
Study Type : In Vitro Study
Additional Links
Substances : Catechin , Curcumin
Diseases : Leukemia: Chronic Lymphocytic Leukemia (CLL)
Pharmacological Actions : Apoptotic
Additional Keywords : Natural Substance Synergy
[+]

Xanthohumol, a compound found within hops, induces programmed cell death in CLL cell lines. Oct 01, 2009

Pubmed Data : Anticancer Res. 2009 Oct;29(10):3797-805. PMID: 19846911
Article Published Date : Oct 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Hops
Diseases : Leukemia: Chronic Lymphocytic Leukemia (CLL)
Pharmacological Actions : Apoptotic
[+]

EGCG, a compound found within green tea, is effective and well-tolerated in patients with chronic lymphocytic leukemia. Aug 10, 2009

Pubmed Data : J Clin Oncol. 2009 Aug 10;27(23):3808-14. Epub 2009 May 26. PMID: 19470922
Article Published Date : Aug 10, 2009
Additional Links
Substances : EGCG (Epigallocatechin gallate), Green Tea
Diseases : Chronic Lymphocytic Leukemia

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One man's Harvard-documented remission of incurable cancer using only natural methods
Written by Glenn Sabin
“Twenty-five years ago my doctors had no cure for my cancer. So I went on a quest to find my own treatment. This is my story.”

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