Huntington Disease

Views 5184
Download the GMI DOC on this Topic

Sign in to Purchase/Download Documents

Sign in / Register

Focus Your Research

Click any topic below to filter + focus research
66 Substances Researched for Huntington Disease
NameACCKFocus
EPA (Eicosapentaenoic Acid)330Locked
Cannabidiol719Locked
Cannabis415Locked
Creatine313Locked
Delta-tetrahydrocannabinol (THC)313Locked
Eicosapentaenoic acid (EPA) 210Locked
Ginsenosides710Locked
Vitamin B-5 (Pantothenic Acid)110Locked
Cannabinoids 69Locked
Coenzyme Q1047Locked
Resveratrol57Locked
Curcumin56Locked
Catechin 15Locked
Chrysin35Locked
Melatonin45Locked
Rutin35Locked
Ashwagandha34Locked
Sesamol24Locked
6-Shogaol12Locked
Berberine12Locked
Betulinic acid12Locked
Carbon 6012Locked
EGCG (Epigallocatechin gallate)12Locked
Ellagic Acid12Locked
Emodin12Locked
False Black Pepper12Locked
Ginseng (American)12Locked
Ginseng (Asian)12Locked
Ginseng (Korean)12Locked
Goji12Locked
Green Tea12Locked
Guarana12Locked
Ligustrazine12Locked
Mangiferin12Locked
Naringenin 12Locked
Quercetin12Locked
Safranal12Locked
Thymoquinone12Locked
Amla Fruit11Locked
Astaxanthin11Locked
Avocado11Locked
Bacopa11Locked
Bamboo11Locked
Caffeic acid phenethyl ester11Locked
Carnosic Acid11Locked
Carotenoids11Locked
Fisetin11Locked
Flavonoids11Locked
Garlic: Aged11Locked
Ginseng11Locked
Lactobacillus plantarum11Locked
Licorice11Locked
Lotus 11Locked
Moringa oleifera11Locked
Myricetin11Locked
Panax Ginseng11Locked
Piperine11Locked
Punicic acid 11Locked
Raspberry11Locked
Rosmarinic acid11Locked
Ruta Graveolens11Locked
Stilbenes11Locked
Tauroursodeoxycholic acid11Locked
Vitamin C11Locked
Vitamin D11Locked
cottonseed oil (gossypol)11Locked
2 Problem Substances Researched for Huntington Disease
NameACCKFocus
Sodium Fluoride12Locked
Gluten11Locked
5 Therapeutic Actions Researched for Huntington Disease
NameACCKFocus
Drumming 110Locked
Exercise: Endurance110Locked
Dietary Modification: Low Carbohydrate/Ketogenic12Locked
Exercise12Locked
Dietary Modification: Mediterranean Diet11Locked

View the Evidence:
103 Abstracts with Huntington Disease Research

[+]

Efficacy of ethyl-EPA as a treatment for Huntington disease.Mar 19, 2019

Pubmed Data : Acta Neuropsychiatr. 2019 Mar 20:1-38. Epub 2019 Mar 20. PMID: 30890195
Article Published Date : Mar 19, 2019
Study Type : Meta Analysis, Review
Additional Links
Substances : EPA (Eicosapentaenoic Acid)
Diseases : Huntington Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Creatine reduces oxidative injury to DNA in patients with Huntington's disease. Jan 24, 2006

Pubmed Data : Neurology. 2006 Jan 24;66(2):250-2. PMID: 16434666
Article Published Date : Jan 24, 2006
Study Type : Human Study
Additional Links
Substances : Creatine
Diseases : Huntington Disease
[+]

Eiocosapentaenoic acid significantly reduces brain atrophy in Huntington's disease. Sep 01, 2008

Pubmed Data : J Int Med Res. 2008 Sep-Oct;36(5):896-905. PMID: 18831882
Article Published Date : Sep 01, 2008
Study Type : Human Study
Additional Links
Substances : Eicosapentaenoic acid (EPA) , EPA (Eicosapentaenoic Acid)
Diseases : Huntington Disease
[+]

Huntington disease patients are amenable to a specific exercise-induced therapeutic strategy.Dec 31, 2016

Pubmed Data : J Neurol. 2017 Jan ;264(1):32-39. Epub 2016 Oct 17. PMID: 27747393
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Diseases : Huntington Disease
Therapeutic Actions : Exercise: Endurance
Pharmacological Actions : Cardioprotective, Neuroprotective Agents
[+]

Improved Executive Function and Callosal White Matter Microstructure after Rhythm Exercise in Huntington's Disease.Dec 31, 2013

Pubmed Data : J Huntingtons Dis. 2014 ;3(3):273-83. PMID: 25300331
Article Published Date : Dec 31, 2013
Study Type : Human Study
Additional Links
Diseases : Huntington Disease
Therapeutic Actions : Drumming
[+]

Pantothenate deficiency could lead to neurodegeneration/dementia in Huntington's disease that might be preventable by treatment with vitamin B5.Jun 10, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Metabolites. 2019 Jun 11 ;9(6). Epub 2019 Jun 11. PMID: 31212603
Article Published Date : Jun 10, 2019
Study Type : Human Study
Additional Links
Substances : Vitamin B-5 (Pantothenic Acid)
Diseases : Dementia, Huntington Disease, Neurodegenerative Diseases, Vitamin B Deficiency
Pharmacological Actions : Neuroprotective Agents
[+]

Sativex is safe and well tolerated in patients with HD, with no severe adverse events or clinical worsening. May 08, 2016

Pubmed Data : J Neurol. 2016 May 9. Epub 2016 May 9. PMID: 27159993
Article Published Date : May 08, 2016
Study Type : Human Study
Additional Links
Substances : Cannabidiol, Cannabis, Delta-tetrahydrocannabinol (THC)
Diseases : Huntington Disease
Additional Keywords : Plant Extracts, Safety of Natural Substances
[+]

Neurorescue activity, APP regulation and amyloid-beta peptide reduction by novel multi-functional brain permeable iron- chelating- antioxidants, M-30 and green tea polyphenol, EGCG.Sep 01, 2007

Pubmed Data : Curr Alzheimer Res. 2007 Sep ;4(4):403-11. PMID: 17908043
Article Published Date : Sep 01, 2007
Study Type : Human In Vitro
Additional Links
Substances : Catechin
Diseases : Amyotrophic Lateral Sclerosis, Huntington Disease, Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Regenerative
Additional Keywords : Nerve Regeneration
[+]

6-shogaol against 3-Nitropropionic acid-induced Huntington's disease.Dec 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2024 ;19(7):e0305358. Epub 2024 Jul 15. PMID: 39008492
Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Substances : 6-Shogaol
Diseases : Huntington Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, NF-kappaB Inhibitor, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

A ketogenic diet delays weight loss and does not impair working memory or motor function in the mouse model of Huntington's disease.Apr 09, 2011

Pubmed Data : Physiol Behav. 2011 Apr 9;103(5):501-507. Epub 2011 Apr 9. PMID: 21501628
Article Published Date : Apr 09, 2011
Study Type : Animal Study
Additional Links
Diseases : Huntington Disease
Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic
[+]

Anti-inflammatory effects of ellagic acid and vanillic acid against quinolinic acid-induced model of Huntington's disease.Nov 04, 2022

Pubmed Data : Eur J Pharmacol. 2022 Nov 5 ;934:175316. Epub 2022 Oct 6. PMID: 36209926
Article Published Date : Nov 04, 2022
Study Type : Animal Study
Additional Links
Substances : Ellagic Acid
Diseases : Huntington Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Neuroprotective Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Berberine could effectively alleviate motor dysfunction and prolong the survival of transgenic N171-82Q HD mice.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(7):e0134142. Epub 2015 Jul 30. PMID: 26225560
Article Published Date : Dec 31, 2014
Study Type : Transgenic Animal Study
Additional Links
Substances : Berberine
Diseases : Huntington Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Betulinic acid hydroxamate has the potential for further pharmacological development of a novel drug candidate for the treatment of Huntington's disease.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neurotherapeutics. 2021 07 ;18(3):1849-1861. Epub 2021 Aug 2. PMID: 34339019
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Betulinic acid
Diseases : Huntington Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Cannabigerol could be used for the treatment of neurodegenerative diseases such as Huntington's disease.Dec 31, 2014

Pubmed Data : Neurotherapeutics. 2015 Jan ;12(1):185-99. PMID: 25252936
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Cannabinoids
Diseases : Huntington Disease, Neurodegenerative Diseases
Pharmacological Actions : Neuroprotective Agents
[+]

Cannabis based medicine could be used as a neuroprotective agent capable of delaying disease progression in Huntington's disease.Aug 31, 2011

Pubmed Data : J Neurosci Res. 2011 Sep ;89(9):1509-18. Epub 2011 Jun 14. PMID: 21674569
Article Published Date : Aug 31, 2011
Study Type : Animal Study
Additional Links
Substances : Cannabidiol, Cannabis, Delta-tetrahydrocannabinol (THC)
Diseases : Huntington Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Cannabis extracts could be neuroprotective agents, delaying disease progression in a proinflammatory model of Huntington’s disease.May 15, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : ACS Chem Neurosci. 2012 May 16 ;3(5):400-6. Epub 2012 Feb 9. PMID: 22860209
Article Published Date : May 15, 2012
Study Type : Animal Study
Additional Links
Substances : Cannabinoids , Cannabis
Diseases : Huntington Disease, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Chrysin ameliorates 3 nitropropinoic acid induced neurotoxicity targeting behavioural, biochemical and histological alterations.Sep 15, 2020

Pubmed Data : Int J Neurosci. 2020 Sep 16:1-9. Epub 2020 Sep 16. PMID: 32901525
Article Published Date : Sep 15, 2020
Study Type : Animal Study
Additional Links
Substances : Chrysin
Diseases : Huntington Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Chrysin can serve as a potential therapeutic agent on 3-Nitropropionic acid induced mitochondrial deficits and subsequent apoptosis.Sep 26, 2016

Pubmed Data : Biomed Pharmacother. 2016 Sep 27 ;84:514-525. Epub 2016 Aug 27. PMID: 27690136
Article Published Date : Sep 26, 2016
Study Type : Animal Study
Additional Links
Substances : Chrysin
Diseases : Huntington Disease
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

Coenzyme q10 appears to have significant therapeutic value in a mouse experimental model of Huntington's disease. Jun 01, 2006

Pubmed Data : Biochim Biophys Acta. 2006 Jun;1762(6):616-26. Epub 2006 Apr 17. PMID: 16647250
Article Published Date : Jun 01, 2006
Study Type : Animal Study
Additional Links
Substances : Coenzyme Q10
Diseases : Huntington Disease
[+]

Coenzyme Q10 demonstrated significant therapeutic effects in transgenic mouse model of ALS and Huntington's disease. Apr 01, 2002

Pubmed Data : Free Radic Res. 2002 Apr;36(4):455-60. PMID: 12069110
Article Published Date : Apr 01, 2002
Study Type : Transgenic Animal Study
Additional Links
Substances : Coenzyme Q10
Diseases : Amyotrophic Lateral Sclerosis, Huntington Disease, Neurodegenerative Diseases
[+]

Combination therapy using CoQ(10) and creatine may be useful in the treatment of neurodegenerative diseases such as Parkinson's disease and Huntington Disease.Jun 01, 2009

Pubmed Data : J Neurochem. 2009 Jun;109(5):1427-39. Epub 2009 Mar 28. PMID: 19476553
Article Published Date : Jun 01, 2009
Study Type : Animal Study
Additional Links
Substances : Coenzyme Q10, Creatine
Diseases : Huntington Disease, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Natural Substance Synergy
[+]

Curcumin significantly ameliorates disease symptoms in a Drosophila model of Huntington's disease.Dec 31, 2015

Pubmed Data : Sci Rep. 2016 ;6:18736. Epub 2016 Jan 5. PMID: 26728250
Article Published Date : Dec 31, 2015
Study Type : Insect Study
Additional Links
Substances : Curcumin
Diseases : Huntington Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Fullerenols prevent neuron death and reduce oxidative stress in drosophila Huntington's disease model.Dec 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cells. 2022 Dec 31 ;12(1). Epub 2022 Dec 31. PMID: 36611963
Article Published Date : Dec 30, 2022
Study Type : Insect Study
Additional Links
Substances : Carbon 60
Diseases : Brain: Oxidative Stress, Huntington Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Ginsenoside compound K reduces the progression of Huntington's disease.Jun 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ginseng Res. 2022 Jul ;46(4):572-584. Epub 2021 Nov 11. PMID: 35818427
Article Published Date : Jun 30, 2022
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Huntington Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Ginsenoside Rg1 exerts neuroprotective effects in 3-nitropronpionic acid-induced mouse model of Huntington's disease.Nov 18, 2020

Pubmed Data : Acta Pharmacol Sin. 2020 Nov 19. Epub 2020 Nov 19. PMID: 33214696
Article Published Date : Nov 18, 2020
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Huntington Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Ginsenosides offer a potential therapeutic choice for the treatment of Huntington's disease. Jun 01, 2009

Pubmed Data : J Neurosci Res. 2009 Jun;87(8):1904-12. PMID: 19185022
Article Published Date : Jun 01, 2009
Study Type : Animal Study
Additional Links
Substances : Ginseng (American), Ginseng (Asian), Ginseng (Korean), Ginsenosides
Diseases : Huntington Disease
[+]

Goji polysaccharide may be potentially useful for treating Huntington's disease.Jul 31, 2016

Pubmed Data : Int J Dev Neurosci. 2016 Aug ;52:66-74. Epub 2016 May 16. PMID: 27196502
Article Published Date : Jul 31, 2016
Study Type : Transgenic Animal Study
Additional Links
Substances : Goji
Diseases : Huntington Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Polysaccharides
[+]

Guarana hydroalcoholic extract has therapeutic potential in combating age-related diseases associated with protein misfolding and accumulation.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:9241308. Epub 2018 Jul 4. PMID: 30116496
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Guarana
Diseases : Alzheimer's Disease, Huntington Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Huntingtons disease mice infected with T. gondii demonstrate early kynurenine pathway activation, altered immune responses, and premature mortality.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2016 ;11(9):e0162404. Epub 2016 Sep 9. PMID: 27611938
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Diseases : Huntington Disease, Toxoplasma gondii Infection
Additional Keywords : Risk Factors
[+]

Melatonin inhibits cytosolic mitochondrial-DNA induced neuroinflammatory signaling in accelerated aging and neurodegeneration.Mar 16, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Invest. 2020 Mar 17. Epub 2020 Mar 17. PMID: 32182222
Article Published Date : Mar 16, 2020
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Aging: Brain , Huntington Disease, Neurodegenerative Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Nano-formulated thymoquinone suspension can efficiently culminate 3-NP induced Huntington's disease progression.Sep 30, 2018

Pubmed Data : Metab Brain Dis. 2018 Oct ;33(5):1459-1470. Epub 2018 May 31. PMID: 29855977
Article Published Date : Sep 30, 2018
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Huntington Disease, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Naringenin mitigates behavioral alterations and provides neuroprotection against 3-nitropropinoic acid-induced Huntington's disease like symptoms.Apr 14, 2021

Pubmed Data : Nutr Neurosci. 2021 Apr 15:1-11. Epub 2021 Apr 15. PMID: 33856270
Article Published Date : Apr 14, 2021
Study Type : Animal Study
Additional Links
Substances : Naringenin
Diseases : Huntington Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Neurodegenerative diseases linked directly to mitochondrial malfunction may benefit greatly from CBD-based medicines.Feb 17, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neurosci. 2009 Feb 18 ;29(7):2053-63. PMID: 19228959
Article Published Date : Feb 17, 2009
Study Type : Animal Study
Additional Links
Substances : Cannabidiol
Diseases : Friedreich Ataxia, Huntington Disease, Mitochondrial Dysfunction , Neurodegenerative Diseases
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

Neuroprotective activity of tetramethylpyrazine against 3-nitropropionic acid induced Huntington's disease-like symptoms.Aug 31, 2018

Pubmed Data : Biomed Pharmacother. 2018 Sep ;105:1254-1268. Epub 2018 Jun 22. PMID: 30021362
Article Published Date : Aug 31, 2018
Study Type : Animal Study
Additional Links
Substances : Ligustrazine
Diseases : Huntington Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Neuroprotective effect of aloe emodin against Huntington's disease-like symptoms.Jun 05, 2023

Pubmed Data : Food Funct. 2023 Jun 6 ;14(11):5205-5216. Epub 2023 Jun 6. PMID: 37191091
Article Published Date : Jun 05, 2023
Study Type : Transgenic Animal Study
Additional Links
Substances : Emodin
Diseases : Huntington Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Neuroprotective effects of rutin on ASH neurons in Caenorhabditis elegans model of Huntington's disease.Jul 25, 2021

Pubmed Data : Nutr Neurosci. 2021 Jul 26:1-14. Epub 2021 Jul 26. PMID: 34311678
Article Published Date : Jul 25, 2021
Study Type : Animal Study
Additional Links
Substances : Rutin
Diseases : Huntington Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Neuroprotective potency of mangiferin against 3-nitropropionic acid induced Huntington's disease-like symptoms.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2023 ;14:1189957. Epub 2023 Jul 13. PMID: 37521470
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Mangiferin
Diseases : Huntington Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Quercetin supplementation is effective in improving mitochondrial dysfunctions induced by 3-nitropropionic acid: implications in Huntington's disease.Feb 28, 2013

Pubmed Data : Biochim Biophys Acta. 2013 Mar ;1832(3):421-30. Epub 2012 Dec 4. PMID: 23220257
Article Published Date : Feb 28, 2013
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Huntington Disease, Lipid Peroxidation, Mitochondrial Dysfunction
Pharmacological Actions : Antioxidants, Superoxide Dismutase Up-regulation
[+]

Resveratrol may inhibit the progression of motor dysfunction and cognitive impairment in a rat experimental model of Huntington's disease. Sep 01, 2006

Pubmed Data : Behav Pharmacol. 2006 Sep;17(5-6):485-92. PMID: 16940769
Article Published Date : Sep 01, 2006
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Huntington Disease
[+]

Resveratrol protects against peripheral deficits in a mouse model of Huntington's disease.Sep 01, 2010

Pubmed Data : Exp Neurol. 2010 Sep;225(1):74-84. Epub 2010 Jun 1. PMID: 20561979
Article Published Date : Sep 01, 2010
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Huntington Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Stilbenes
[+]

Safranal prevented the motor dysfunction induced by 3-NP in animal model of Huntington's disease.Feb 20, 2021

Pubmed Data : Neurochem Res. 2021 Feb 21. Epub 2021 Feb 21. PMID: 33611726
Article Published Date : Feb 20, 2021
Study Type : Animal Study
Additional Links
Substances : Safranal
Diseases : Huntington Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Sesamol attenuates experimentally induced Huntington-like changes in an animal model. Jan 01, 2009

Pubmed Data : J Asian Nat Prod Res. 2009 ;11(5):439-50. PMID: 19504387
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Substances : Sesamol
Diseases : Huntington Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Sesamol protects against cognitive dysfunction and altered glutathione redox balance. Jul 01, 2010

Pubmed Data : Basic Clin Pharmacol Toxicol. 2010 Jul ;107(1):577-82. Epub 2010 Jan 25. PMID: 20102363
Article Published Date : Jul 01, 2010
Study Type : Animal Study
Additional Links
Substances : Sesamol
Diseases : Cognitive Decline/Dysfunction, Huntington Disease, Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Sodium flouride exposure during pregnancy may interfere with normal development and increase the risk of neurological and psychiatric disorders in adulthood.Jun 01, 2010

Pubmed Data : Eur Rev Med Pharmacol Sci. 2010 Jun;14(6):507-12. PMID: 20712257
Article Published Date : Jun 01, 2010
Study Type : Animal Study
Additional Links
Diseases : Fluoride Toxicity , Huntington Disease, Obsessive-Compulsive Disorder, Prenatal Chemical Exposures, Schizophrenia, Tourette Syndrome
Problem Substances : Sodium Fluoride
Adverse Pharmacological Actions : Genotoxic, Teratogenic
[+]

The polyphenol in green tea known as EGCG may inhibit the progression of Huntington's disease. Sep 15, 2006

Pubmed Data : Hum Mol Genet. 2006 Sep 15;15(18):2743-51. Epub 2006 Aug 7. PMID: 16893904
Article Published Date : Sep 15, 2006
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate), Green Tea
Diseases : Huntington Disease
[+]

These findings indicate that aberrant urea metabolism could be the primary biochemical disruption initiating neuropathogenesis in Huntington's disease.Dec 10, 2017

Pubmed Data : Proc Natl Acad Sci U S A. 2017 Dec 11. Epub 2017 Dec 11. PMID: 29229845
Article Published Date : Dec 10, 2017
Study Type : Transgenic Animal Study
Additional Links
Diseases : Huntington Disease, Hyperuricemia
Additional Keywords : Increased Risk
[+]

These findings suggest the neuroprotective effect of embelin against Huntington's disease.Jan 31, 2016

Pubmed Data : Biomed Pharmacother. 2016 Feb ;77:52-8. Epub 2015 Dec 15. PMID: 26796265
Article Published Date : Jan 31, 2016
Study Type : Animal Study
Additional Links
Substances : False Black Pepper
Diseases : Huntington Disease, Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Neuroprotective Agents
[+]

These results indicate immense potential of Withaferin A for the treatment of Huntington disease.Apr 25, 2021

Pubmed Data : Mol Neurobiol. 2021 Apr 26. Epub 2021 Apr 26. PMID: 33904021
Article Published Date : Apr 25, 2021
Study Type : Animal Study
Additional Links
Substances : Ashwagandha
Diseases : Huntington Disease
Pharmacological Actions : Heat Shock Protein Inducer, Neuroprotective Agents
[+]

These results suggest that rutin could be a beneficial choice in treating Huntington's disease.Dec 07, 2016

Pubmed Data : Metab Brain Dis. 2016 Dec 8. Epub 2016 Dec 8. PMID: 27928694
Article Published Date : Dec 07, 2016
Study Type : Animal Study
Additional Links
Substances : Rutin
Diseases : Huntington Disease
Pharmacological Actions : Antioxidants
[+]

This study demonstrates that CBD provides neuroprotection against 3NP-induced striatal damage.Jul 31, 2007

Pubmed Data : Eur J Neurosci. 2007 Aug ;26(4):843-51. Epub 2007 Aug 2. PMID: 17672854
Article Published Date : Jul 31, 2007
Study Type : Animal Study
Additional Links
Substances : Cannabidiol, Cannabinoids
Diseases : Huntington Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Superoxide Dismutase Up-regulation
[+]

Treadmill exercise rescues mitochondrial function and motor behavior in the CAG140 knock-in mouse model of Huntington's disease.Jan 04, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Chem Biol Interact. 2020 Jan 5 ;315:108907. Epub 2019 Nov 26. PMID: 31778667
Article Published Date : Jan 04, 2020
Study Type : Animal Study
Additional Links
Diseases : Huntington Disease
Therapeutic Actions : Exercise
Pharmacological Actions : Neuroprotective Agents
[+]

Ruta graveolens as a potential source of neuroactive compounds to promote and restore neural functions.Apr 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Tradit Complement Med. 2020 May ;10(3):309-314. Epub 2020 Jun 4. PMID: 32670826
Article Published Date : Apr 30, 2020
Study Type : Review
Additional Links
Substances : Ruta Graveolens
Diseases : Alzheimer's Disease, Huntington Disease, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

A large number of neurologic syndromes may result from gluten intolerance.Apr 01, 2005

Pubmed Data : Gastroenterology. 2005 Apr;128(4 Suppl 1):S92-7. PMID: 15825133
Article Published Date : Apr 01, 2005
Study Type : Commentary
Additional Links
Diseases : Ataxia: Cerebellar, Autism Spectrum Disorders, Chorea, Gluten Sensitivity, Guillain-Barre Syndrome, Huntington Disease, Myelopathy, Neuropathy
Problem Substances : Gluten
[+]

A review exploring the multifaceted neuroprotective actions of amla.Mar 07, 2019

Pubmed Data : Metab Brain Dis. 2019 Mar 8. Epub 2019 Mar 8. PMID: 30848470
Article Published Date : Mar 07, 2019
Study Type : Review
Additional Links
Substances : Amla Fruit
Diseases : Alzheimer's Disease, Depression, Epilepsy, Huntington Disease, Parkinson's Disease, Tardive Dyskinesia
Pharmacological Actions : Neuroprotective Agents
[+]

Aqueous extract of Glycyrrhiza inflata inhibits aggregation by upregulating PPARGC1A and NFE2L2-ARE pathways in cell models of spinocerebellar ataxia 3.May 31, 2014

Pubmed Data : Free Radic Biol Med. 2014 Jun ;71:339-350. Epub 2014 Mar 25. PMID: 24675225
Article Published Date : May 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Licorice
Diseases : Huntington Disease, Oxidative Stress
Pharmacological Actions : Antioxidant, Neuroprotective Agents, Superoxide Dismutase Up-regulation
Additional Keywords : Plant Extracts
[+]

Astaxanthin has protection against neuronal excitotoxicity.Oct 17, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mar Drugs. 2022 Oct 18 ;20(10). Epub 2022 Oct 18. PMID: 36286468
Article Published Date : Oct 17, 2022
Study Type : In Vitro Study
Additional Links
Substances : Astaxanthin
Diseases : Alzheimer's Disease, Epilepsy, Huntington Disease, Mitochondrial Dysfunction , Neurodegenerative Diseases, Stroke
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Benefits of curcumin in brain disorders.Aug 31, 2019

Pubmed Data : Biofactors. 2019 Sep ;45(5):666-689. Epub 2019 Jun 11. PMID: 31185140
Article Published Date : Aug 31, 2019
Study Type : Review
Additional Links
Substances : Curcumin
Diseases : Alzheimer's Disease, Amyotrophic Lateral Sclerosis, Anxiety, Autism Spectrum Disorders, Dementia, Depression, disease, Huntington Disease, Multiple Sclerosis, Parkinson's Disease, Stroke
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Cannabidiol and neurodegeneration: from molecular mechanisms to clinical benefits. Jul 02, 2024

Pubmed Data : Ageing Res Rev. 2024 Jul 3:102386. Epub 2024 Jul 3. PMID: 38969143
Article Published Date : Jul 02, 2024
Study Type : Review
Additional Links
Substances : Cannabidiol
Diseases : Alzheimer's Disease, Amyotrophic Lateral Sclerosis, Huntington Disease, Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Cannabinoids for treatment of dystonia in Huntington's disease.Mar 15, 2018

Pubmed Data : J Huntingtons Dis. 2018 Mar 16. Epub 2018 Mar 16. PMID: 29562549
Article Published Date : Mar 15, 2018
Study Type : Review
Additional Links
Substances : Cannabinoids
Diseases : Huntington Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Carnosic acid is a potential candidate to be listed as a neuroprotective agent by acting on the mitochondria of neural cells.Jan 14, 2018

Pubmed Data : Mol Neurobiol. 2018 Jan 15. Epub 2018 Jan 15. PMID: 29335845
Article Published Date : Jan 14, 2018
Study Type : Review
Additional Links
Substances : Carnosic Acid
Diseases : Alzheimer's Disease, Huntington Disease, Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

CBD may represent a very promising agent with the highest prospect for therapeutic use in neurodegenerative disorders.Dec 31, 2008

Pubmed Data : CNS Neurosci Ther. 2009 ;15(1):65-75. PMID: 19228180
Article Published Date : Dec 31, 2008
Study Type : Review
Additional Links
Substances : Cannabidiol
Diseases : Alzheimer's Disease, Huntington Disease, Multiple Sclerosis, Neurodegenerative Diseases
Pharmacological Actions : Neuroprotective Agents
[+]

Cellular mechanisms of melatonin: Insight from neurodegenerative diseases. Jan 06, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomolecules. 2020 08 7 ;10(8). Epub 2020 Aug 7. PMID: 32784556
Article Published Date : Jan 06, 2020
Study Type : Review
Additional Links
Substances : Melatonin
Diseases : Alzheimer's Disease, Amyotrophic lateral sclerosis (ALS), Huntington Disease, Multiple Sclerosis, Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Creatine may play a neuroprotective role in treating neurodegenerative disorders such as Huntington's disease. Jan 01, 2008

Pubmed Data : Neuromolecular Med. 2008;10(4):275-90. Epub 2008 Nov 13. PMID: 19005780
Article Published Date : Jan 01, 2008
Study Type : Commentary
Additional Links
Substances : Creatine
Diseases : Huntington Disease, Neurodegenerative Diseases
[+]

Curcumin-based nanomedicines in the treatment of inflammatory and immunomodulated diseases.Jan 09, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceutics. 2023 Jan 10 ;15(1). Epub 2023 Jan 10. PMID: 36678859
Article Published Date : Jan 09, 2023
Study Type : Review
Additional Links
Substances : Curcumin
Diseases : Alzheimer's Disease, Atherosclerosis, Coronavirus Infection, Huntington Disease, Inflammatory Bowel Diseases, Liver Fibrosis, Multiple Sclerosis, Parkinson's Disease, Psoriasis, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory
[+]

Curcumin-loaded nanoparticles: a novel therapeutic strategy in treatment of central nervous system disorders.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Nanomedicine. 2019 ;14:4449-4460. Epub 2019 Jun 17. PMID: 31417253
Article Published Date : Dec 31, 2018
Study Type : Review
Additional Links
Substances : Curcumin
Diseases : Alzheimer's Disease, Amyotrophic Lateral Sclerosis, Central Nervous System Diseases, Epilepsy, Huntington Disease, Multiple Sclerosis, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Dietary intake, Mediterranean diet adherence and caloric intake in Huntington's disease.Sep 24, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Sep 25 ;12(10). Epub 2020 Sep 25. PMID: 32992896
Article Published Date : Sep 24, 2020
Study Type : Review
Additional Links
Diseases : Cognitive Decline/Dysfunction, Huntington Disease
Therapeutic Actions : Dietary Modification: Mediterranean Diet
Pharmacological Actions : Neuroprotective Agents
[+]

Discovery of natural compounds as nonpeptidyl inhibitors is a significant transition towards feasible drug development for neurodegenerative disorders.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2015 ;2015:379817. Epub 2015 May 4. PMID: 26064904
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Curcumin, Rosmarinic acid
Diseases : Alzheimer's Disease, Amyotrophic lateral sclerosis (ALS), Huntington Disease, Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Nonpeptidyl Inhibitors
[+]

Effects of Panax ginseng in Neurodegenerative Diseases.Sep 30, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ginseng Res. 2012 Oct ;36(4):342-53. PMID: 23717136
Article Published Date : Sep 30, 2012
Study Type : Review
Additional Links
Substances : Panax Ginseng
Diseases : Alzheimer's Disease, Amyotrophic lateral sclerosis (ALS), Huntington Disease, Multiple Sclerosis, Neurodegenerative Diseases
[+]

Ginseng and its constituents have potential merits in the treatment of cerebral disorders.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2016 ;2016:2614742. Epub 2016 Aug 18. PMID: 27630732
Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Ginseng, Ginsenosides
Diseases : Alzheimer's Disease, Amyotrophic lateral sclerosis (ALS), Central Nervous System Diseases, Huntington Disease, Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Ginsenoside Rd is a promising natural neuroprotective agent. Dec 31, 2021

Pubmed Data : Phytomedicine. 2022 Jan ;95:153883. Epub 2021 Dec 8. PMID: 34952508
Article Published Date : Dec 31, 2021
Study Type : Review
Additional Links
Substances : Ginsenosides
Diseases : Alzheimer's Disease, Cerebral Ischemia, Depression, Huntington Disease, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Phytotherapy
[+]

Gossypol induces autophagic degradation of mutant huntingtin.Jan 24, 2021

Pubmed Data : Acta Pharmacol Sin. 2021 Jan 25. Epub 2021 Jan 25. PMID: 33495516
Article Published Date : Jan 24, 2021
Study Type : In Vitro Study
Additional Links
Substances : cottonseed oil (gossypol)
Diseases : Huntington Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Identification and microbial production of the raspberry phenol salidroside that is active against Huntington’s disease.Dec 31, 2018

Pubmed Data : Plant Physiol. 2019 03 ;179(3):969-985. Epub 2018 Nov 5. PMID: 30397021
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Raspberry
Diseases : Huntington Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

L. plantarum 200655 might be used as a prophylactic functional ingredient to prevent neurodegenerative disease.Jan 16, 2021

Pubmed Data : Probiotics Antimicrob Proteins. 2021 Jan 17. Epub 2021 Jan 17. PMID: 33454870
Article Published Date : Jan 16, 2021
Study Type : In Vitro Study
Additional Links
Substances : Lactobacillus plantarum
Diseases : Alzheimer's Disease, Huntington Disease, Parkinson's Disease
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents, Prophylactic Agents
[+]

Lig-8, a compound extracted from bamboo, exhibits neuroprotective properties. Sep 01, 2007

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : CNS Drug Rev. 2007 Fall;13(3):296-307. PMID: 17894646
Article Published Date : Sep 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Bamboo
Diseases : Alzheimer's Disease, Glaucoma, Huntington Disease, Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

Melatonin is selectively taken up by mitochondrial membranes which prevents oxidative stress induced mitochondrial dysfunction.Jun 17, 2015

Pubmed Data : Rejuvenation Res. 2015 Jun 18. Epub 2015 Jun 18. PMID: 26087000
Article Published Date : Jun 17, 2015
Study Type : Review
Additional Links
Substances : Melatonin
Diseases : Alzheimer's Disease, Amyotrophic Lateral Sclerosis, Huntington Disease, Mitochondrial Dysfunction , Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Mitochondrial Metabolism
[+]

Melatonin: A review of its potential functions and effects on neurological diseases.Nov 08, 2019

Pubmed Data : Rev Neurol (Paris). 2019 Nov 9. Epub 2019 Nov 9. PMID: 31718830
Article Published Date : Nov 08, 2019
Study Type : Review
Additional Links
Substances : Melatonin
Diseases : Alzheimer's Disease, Amyotrophic Lateral Sclerosis, Epilepsy, Headache, Huntington Disease, Multiple Sclerosis, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents, Prophylactic Agents
[+]

Neferine attenuates the protein level and toxicity of mutant huntingtin in PC-12 cells.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2015 ;20(3):3496-514. Epub 2015 Feb 18. PMID: 25699594
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Lotus
Diseases : Huntington Disease, Neurodegenerative Diseases
Pharmacological Actions : Anti-Apoptotic, Autophagy Up-regulation, Neuroprotective Agents
[+]

Neuroprotection of coenzyme Q10 in neurodegenerative diseases. Dec 31, 2015

Pubmed Data : Curr Top Med Chem. 2016 ;16(8):858-66. PMID: 26311425
Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Coenzyme Q10
Diseases : Alzheimer's Disease, Huntington Disease, Neurodegenerative Diseases, Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Neuroprotection with Bacopa monnieri-A review of experimental evidence.Feb 28, 2021

Pubmed Data : Mol Biol Rep. 2021 Mar ;48(3):2653-2668. Epub 2021 Mar 6. PMID: 33675463
Article Published Date : Feb 28, 2021
Study Type : Review
Additional Links
Substances : Bacopa
Diseases : Alzheimer's Disease, Cerebral Ischemia, Epilepsy, Huntington Disease, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Neuroprotective potential of caffeic acid phenethyl ester in CNS disorders.Jun 07, 2021

Pubmed Data : Curr Neuropharmacol. 2021 Jun 8. Epub 2021 Jun 8. PMID: 34102977
Article Published Date : Jun 07, 2021
Study Type : Review
Additional Links
Substances : Caffeic acid phenethyl ester
Diseases : Alzheimer's Disease, Amyotrophic Lateral Sclerosis, Anxiety, Brain Injury: Traumatic, Depression, Epilepsy, Huntington Disease, Parkinson's Disease, Stroke
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Neuroprotective potential of Moringa oleifera mediated by NF-kB/Nrf2/HO-1 signaling pathway.Oct 06, 2022

Pubmed Data : J Food Biochem. 2022 Oct 7:e14451. Epub 2022 Oct 7. PMID: 36206551
Article Published Date : Oct 06, 2022
Study Type : Review
Additional Links
Substances : Moringa oleifera
Diseases : Alzheimer's Disease, Huntington Disease, Parkinson's Disease
Pharmacological Actions : anti-inflammatory, Antioxidants, Heme oxygenase-1 up-regulation, Neuroprotective Agents, NF-kappaB Inhibitor, Nrf2 activation
[+]

New therapeutic approaches to and mechanisms of ginsenoside Rg1 against neurological diseases.Aug 15, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cells. 2022 Aug 16 ;11(16). Epub 2022 Aug 16. PMID: 36010610
Article Published Date : Aug 15, 2022
Study Type : Review
Additional Links
Substances : Ginsenosides
Diseases : Alzheimer's Disease, Cerebral Ischemia, Huntington Disease, Parkinson's Disease, Stroke
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Punicic acid and its role in the prevention of neurological disorders.Jan 17, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Foods. 2022 Jan 18 ;11(3). Epub 2022 Jan 18. PMID: 35159404
Article Published Date : Jan 17, 2022
Study Type : Review
Additional Links
Substances : Punicic acid
Diseases : Alzheimer's Disease, Huntington Disease, Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Resveratrol could be used to slow down Huntington's Disease progression.May 18, 2017

Pubmed Data : Neurochem Int. 2017 May 19. Epub 2017 May 19. PMID: 28532681
Article Published Date : May 18, 2017
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Huntington Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Resveratrol: a natural compound with pharmacological potential in neurodegenerative diseases.Dec 31, 2007

Pubmed Data : CNS Neurosci Ther. 2008 ;14(3):234-47. Epub 2008 Jul 29. PMID: 18684235
Article Published Date : Dec 31, 2007
Study Type : Review
Additional Links
Substances : Resveratrol, Stilbenes
Diseases : Alzheimer's Disease, Amyotrophic lateral sclerosis (ALS), Huntington Disease, Neurodegenerative Diseases
Pharmacological Actions : Neuroprotective Agents
[+]

Role of vitamins in neurodegenerative diseases: a review. Nov 18, 2021

Pubmed Data : CNS Neurol Disord Drug Targets. 2021 Nov 19. Epub 2021 Nov 19. PMID: 34802410
Article Published Date : Nov 18, 2021
Study Type : Review
Additional Links
Substances : Vitamin C, Vitamin D
Diseases : Huntington Disease, Neurodegenerative Diseases, Parkinson's Disease, Vitamin C Deficiency, Vitamin D Deficiency
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Rutin may be a promising neuroprotective compound for the treatment of neurodegenerative diseases.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:6241017. Epub 2018 Jun 27. PMID: 30050657
Article Published Date : Dec 31, 2017
Study Type : Review
Additional Links
Substances : Rutin
Diseases : Alzheimer's Disease, Huntington Disease, Parkinson's Disease, Prion Diseases
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Suggesting 7,8-dihydroxyflavone as a promising nutraceutical against CNS disorders.Dec 31, 2020

Pubmed Data : Neurochem Int. 2021 09 ;148:105068. Epub 2021 May 20. PMID: 34022252
Article Published Date : Dec 31, 2020
Study Type : Review
Additional Links
Diseases : Alzheimer's Disease, Huntington Disease, Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Tauroursodeoxycholic acid (TUDCA) may have therapeutic value in neurodegenerative illnesses. Apr 30, 2014

Pubmed Data : Glob Adv Health Med. 2014 May ;3(3):58-69. PMID: 24891994
Article Published Date : Apr 30, 2014
Study Type : Review
Additional Links
Substances : Tauroursodeoxycholic acid
Diseases : Amyotrophic lateral sclerosis (ALS), Huntington Disease, Multiple Sclerosis, Neurodegenerative Diseases
Pharmacological Actions : Anti-Apoptotic
[+]

The critical review results indicate that compounds in avocado are unique antioxidants, and thus may be promising as effective neuropreventive agents.Dec 31, 2015

Pubmed Data : Adv Neurobiol. 2016 ;12:337-54. PMID: 27651262
Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Avocado
Diseases : Alzheimer's Disease, Amyotrophic lateral sclerosis (ALS), Huntington Disease, Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Avocado, Huntington Disease, Neurodegenerative diseases, Parkinson's disease
[+]

The findings indicate that chrysin has protective effects against neurological conditions by modulating oxidative stress, inflammation, and apoptosis.Jul 15, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2021 Jul 16 ;141:111906. Epub 2021 Jul 16. PMID: 34328092
Article Published Date : Jul 15, 2021
Study Type : Review
Additional Links
Substances : Chrysin
Diseases : Alzheimer's Disease, Brain Inflammation , Cerebral Ischemia, Epilepsy, Huntington Disease, Parkinson's Disease
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

The neuroprotective potential of carotenoids in vitro and in vivo.Jul 20, 2021

Pubmed Data : Phytomedicine. 2021 Jul 21 ;91:153676. Epub 2021 Jul 21. PMID: 34339943
Article Published Date : Jul 20, 2021
Study Type : Review
Additional Links
Substances : Carotenoids
Diseases : Alzheimer's Disease, Amyotrophic Lateral Sclerosis, Huntington Disease, Parkinson's Disease, Stroke
Pharmacological Actions : Neuroprotective Agents
[+]

The polyphenols fisetin and resveratrol provide neuroprotection in multiple models of Huntington's disease.Jan 15, 2011

Pubmed Data : Hum Mol Genet. 2011 Jan 15;20(2):261-70. Epub 2010 Oct 15. PMID: 20952447
Article Published Date : Jan 15, 2011
Study Type : In Vitro Study
Additional Links
Substances : Fisetin, Resveratrol
Diseases : Huntington Disease
Pharmacological Actions : Neuroprotective Agents
[+]

The potential of flavonoids for the treatment of neurodegenerative diseases.Jun 21, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Jun 22 ;20(12). Epub 2019 Jun 22. PMID: 31234550
Article Published Date : Jun 21, 2019
Study Type : Review
Additional Links
Substances : Flavonoids
Diseases : Alzheimer's Disease, Amyotrophic Lateral Sclerosis, disease, Huntington Disease, Parkinson's Disease
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

The results of the current study reveal the neuroprotective competency of piperine against Huntington disease like symptoms.Feb 24, 2020

Pubmed Data : Nutr Neurosci. 2020 Feb 25:1-10. Epub 2020 Feb 25. PMID: 32093571
Article Published Date : Feb 24, 2020
Study Type : In Vitro Study
Additional Links
Substances : Piperine
Diseases : Huntington Disease
Pharmacological Actions : Neuroprotective Agents
[+]

The review concludes the results of recent studies on Ashwagandha suggesting its extensive potential as neuroprotective in various brain disorders.Apr 15, 2020

Pubmed Data : J Ethnopharmacol. 2020 Apr 16 ;257:112876. Epub 2020 Apr 16. PMID: 32305638
Article Published Date : Apr 15, 2020
Study Type : Review
Additional Links
Substances : Ashwagandha
Diseases : Alzheimer's Disease, Amyotrophic Lateral Sclerosis, Attention Deficit Disorder with Hyperactivity, Autism Spectrum Disorders, Depression, Huntington Disease, Parkinson's Disease, Schizophrenia
Pharmacological Actions : Neuroprotective Agents
[+]

Therapeutic potential of ginsenoside Rg3 and Rf for Huntington's disease. May 31, 2021

Pubmed Data : In Vitro Cell Dev Biol Anim. 2021 Jun ;57(6):641-648. Epub 2021 Jun 14. PMID: 34128157
Article Published Date : May 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Huntington Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Therapeutic potential of myricetin in the treatment of neurological, neuropsychiatric, and neurodegenerative disorders.Jul 17, 2023

Pubmed Data : CNS Neurol Disord Drug Targets. 2023 Jul 18. Epub 2023 Jul 18. PMID: 37461364
Article Published Date : Jul 17, 2023
Study Type : Review
Additional Links
Substances : Myricetin
Diseases : Alzheimer's Disease, Depression, Huntington Disease, Parkinson's Disease, Stroke
Pharmacological Actions : Neuroprotective Agents
[+]

This article reviews the most important current data involving the endocannabinoid system in relation to human diseases.Mar 31, 2017

Pubmed Data : Expert Rev Clin Pharmacol. 2017 Apr ;10(4):443-455. Epub 2017 Feb 28. PMID: 28276775
Article Published Date : Mar 31, 2017
Study Type : Review
Additional Links
Substances : Cannabidiol, Cannabinoids , Delta-tetrahydrocannabinol (THC)
Diseases : Alzheimer's Disease, Huntington Disease, Multiple Sclerosis, Parkinson's Disease
Additional Keywords : Endocannabinoid System, Plant Extracts
[+]

This experimental data provides information for the molecular targets of AGE and its components to mitigate neurodegeneration and neuroinflammation.Aug 31, 2016

Pubmed Data : Neuromolecular Med. 2016 Sep ;18(3):474-82. Epub 2016 Jun 4. PMID: 27263111
Article Published Date : Aug 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Garlic: Aged
Diseases : Alzheimer's Disease, Brain Inflammation , Cerebral Ischemia, Huntington Disease, Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents, NF-E2-Related Factor-2 (Nrf2) Modulator
Additional Keywords : Plant Extracts
[+]

This review details the mechanisms of neurodegeneration and highlights the beneficial effects of cannabinoid treatment.Feb 28, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Br J Pharmacol. 2014 Mar ;171(6):1347-60. PMID: 24172185
Article Published Date : Feb 28, 2014
Study Type : Review
Additional Links
Substances : Cannabinoids , Cannabis
Diseases : Alzheimer's Disease, Brain Inflammation , Huntington Disease, Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neurogenesis, Neuroprotective Agents
[+]

Withania somnifera in neurological disorders: Ethnopharmacological evidence, mechanism of action and its progress in delivery systems.Feb 02, 2021

Pubmed Data : Curr Drug Metab. 2021 Feb 3. Epub 2021 Feb 3. PMID: 33538666
Article Published Date : Feb 02, 2021
Study Type : Review
Additional Links
Substances : Ashwagandha
Diseases : Alzheimer's Disease, Anxiety, Huntington Disease, Parkinson's Disease, Stroke, Tardive Dyskinesia
Pharmacological Actions : Neuroprotective Agents
[+]

EPA improves motor skills in patients with Huntington's disease. Jul 26, 2005

Pubmed Data : Neurology. 2005 Jul 26;65(2):286-92. PMID: 16043801
Article Published Date : Jul 26, 2005
Additional Links
Substances : Eicosapentaenoic acid (EPA) , EPA (Eicosapentaenoic Acid)
Diseases : Huntington Disease

Copyright: alila / 123RF Stock Photo

Huntington Disease Related Articles

Testing a 2,500 Year-Old Hypothesis
Written by John Stuart Reid
If music breathes new life into old blood cells, play on!
Hesperidin: The Citrus Bioflavonoid Powerhouse You Haven't Heard Of
Written by GreenMedInfo Research Group
Hesperidin, a polyphenolic compound extracted from citrus fruits and known for its anti-inflammatory properties, may have beneficial effects in the prevention of cardiovascular and neurodegenerative diseases. Further study indicates that hesperidin may prevent varicose vein formation and be useful in the treatment of hemorrhoids and diabetes, yet many have yet to hear about this powerful flavonoid
Open Sesame! 10 Amazing Health Benefits of This Super-Seed
Written by Sayer Ji, Founder
Given the growing body of scientific support on its health benefits, sesame would be just as at home in a medicine cabinet as it would be a kitchen cupboard
What's Inside an Ayurvedic Medicine Cabinet?
Written by GMI Reporter
Thanks to the preservation of some sacred texts, we have access to the wisdom of 5000 years of medical science. Find out what healing substances have stood the test of time, and are still some of the safest and most potent medicines available today
Green Tea May Have Brain Healing Properties
Written by Sayer Ji, Founder
Research reveals that green tea could be a powerful brain healer by stimulating the activity of a nerve growth factor known as BDNF
6 Ways Drumming Heals Body, Mind and Soul
Written by Sayer Ji, Founder
From slowing the decline in fatal brain disease, to generating a sense of oneness with the universe, drumming's physical and spiritual health benefits may be as old as time itself.

Print Options

Some features are currently member only features. If you are already a member, please login. Otherwise, click here to become a member.
  • Printer-friendly version

Connect with GreenMedInfo

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2025 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.