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31 Substances Researched for Hot Flash
NameACCKFocus
Red Clover460Locked
Genistein431Locked
Isoflavones230Locked
Black Cohosh321Locked
Evening Primrose Oil321Locked
Flaxseed220Locked
Sage220Locked
5-HTP (5-Hydroxytryptophan)110Locked
Alfalfa110Locked
Bee Pollen110Locked
Curcumin110Locked
DHEA (Dehydroepiandrosterone)110Locked
Daidzein110Locked
Dong Quai110Locked
Fenugreek110Locked
Honey110Locked
Lavender: Essential Oil110Locked
Licorice110Locked
Milk Thistle110Locked
Nettle110Locked
Pollen: Flower110Locked
Pumpkin Seed Oil/Meal110Locked
Pycnogenol (Pine Bark)110Locked
Saffron110Locked
Secoisolariciresinol diglucoside (SDG)110Locked
St. Johns Wort110Locked
Valerian110Locked
Vitamin E110Locked
Vitex Agnus110Locked
Kudzu12Locked
Motherwort12Locked
4 Problem Substances Researched for Hot Flash
NameACCKFocus
Antiandrogen110Locked
Arimidex110Locked
Aromatase Inhibitor Drugs110Locked
Fluoxetine (trade name Prozac) 110Locked
4 Therapeutic Actions Researched for Hot Flash
NameACCKFocus
Acupuncture220Locked
Aromatherapy 110Locked
Therapeutic Breathing110Locked
Homeopathic Treatment11Locked

View the Evidence:
41 Abstracts with Hot Flash Research

[+]

A standardised extract of red clover isoflavones had a statistical and clinically significant benefit for treating hot flushes in menopausal women.Jan 14, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Phytomedicine. 2017 Jan 15 ;24:141-147. Epub 2016 Dec 12. PMID: 28160855
Article Published Date : Jan 14, 2017
Study Type : Meta Analysis, Review
Additional Links
Substances : Isoflavones, Red Clover
Diseases : Hot Flash, Perimenopausal Syndrome
Additional Keywords : Phytotherapy, Plant Extracts, Significant Treatment Outcome
[+]

The effect of red clover extract on menopausal symptoms showed a statistically moderate relationship with the reduction in the daily frequency of hot flushes.Apr 10, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2021 Apr 11 ;13(4). Epub 2021 Apr 11. PMID: 33920485
Article Published Date : Apr 10, 2021
Study Type : Meta Analysis, Review
Additional Links
Substances : Red Clover
Diseases : Hot Flash, Menopausal Syndrome
Additional Keywords : Significant Treatment Outcome
[+]

"Supplementation with Pycnogenol® improves signs and symptoms of menopausal transition."Sep 01, 2011

Pubmed Data : Panminerva Med. 2011 Sep ;53(3 Suppl 1):65-70. PMID: 22108479
Article Published Date : Sep 01, 2011
Study Type : Human Study
Additional Links
Substances : Pycnogenol (Pine Bark)
Diseases : Hot Flash, Menopausal Syndrome, Premenopausal Disorders
[+]

5-HTP supplementation increases serotonin levels which may decrease hot flashes. Sep 01, 2005

Pubmed Data : Altern Med Rev. 2005 Sep;10(3):216-21. PMID: 16164376
Article Published Date : Sep 01, 2005
Study Type : Human Study
Additional Links
Substances : 5-HTP (5-Hydroxytryptophan)
Diseases : Hot Flash
[+]

A combination of standardized extracts of black cohosh, dong quai, milk thistle, red clover, American ginseng, chaste-tree berry can be safe and effective for the relief of menopausal symptoms in pre- and postmenopausal women when used for 3 months..Feb 01, 2007

Pubmed Data : Gynecol Endocrinol. 2007 Feb ;23(2):117-22. PMID: 17454163
Article Published Date : Feb 01, 2007
Study Type : Human Study
Additional Links
Substances : Dong Quai, Milk Thistle, Red Clover
Diseases : Hot Flash, Menopausal Syndrome
Additional Keywords : Menopause, Phytotherapy, Plant Extracts
[+]

A comparative study on the effect of black cohosh and evening primrose oil on menopausal hot flashes.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Educ Health Promot. 2018 ;7:36. Epub 2018 Mar 1. PMID: 29619387
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Substances : Black Cohosh, Evening Primrose Oil
Diseases : Hot Flash
[+]

A novel extract of Fenugreek husk alleviates postmenopausal symptoms and helps to establish the hormonal balance.Jul 12, 2016

Pubmed Data : Phytother Res. 2016 Jul 13. Epub 2016 Jul 13. PMID: 27406028
Article Published Date : Jul 12, 2016
Study Type : Human Study
Additional Links
Substances : Fenugreek
Diseases : Hot Flash, Postmenopausal Disorders
Additional Keywords : Plant Extracts, Significant Treatment Outcome
[+]

Acupuncture plus self-care can contribute to a clinically relevant reduction in hot flashes and increased health-related quality of life in postmenopausal women.May 01, 2009

Pubmed Data : Menopause. 2009 May-Jun;16(3):484-93. PMID: 19423996
Article Published Date : May 01, 2009
Study Type : Human Study
Additional Links
Diseases : Hot Flash
Therapeutic Actions : Acupuncture
[+]

Adjuvant treatment with aromatase inhibitors in breast cancer result in higher rates of hot flushes, musculoskeletal complaints, osteoporosis and fractures.Aug 01, 2006

Pubmed Data : Curr Med Res Opin. 2006 Aug;22(8):1609-21. PMID: 16870085
Article Published Date : Aug 01, 2006
Study Type : Human Study
Additional Links
Diseases : Bone Fractures, Breast Cancer, Drug-Induced Toxicity , Hot Flash, Musculoskeletal Complaints, Pain: Musculoskeletal
Additional Keywords : Drug: Tamoxifen
Problem Substances : Arimidex, Aromatase Inhibitor Drugs
[+]

Black cohosh compares favorably to fluoxetine in the treatment of postmenopausal symptoms.Feb 28, 2007

Pubmed Data : Adv Ther. 2007 Mar-Apr;24(2):448-61. PMID: 17565936
Article Published Date : Feb 28, 2007
Study Type : Human Study
Additional Links
Substances : Black Cohosh
Diseases : Hot Flash, Menopausal Syndrome
Additional Keywords : Natural Substances Versus Drugs, Plant Extracts, Superiority of Natural Substances versus Drugs
Problem Substances : Fluoxetine (trade name Prozac)
[+]

Daidzein-rich isoflavone are effective in reducing hot flashes in menopausal women. Apr 24, 2007

Pubmed Data : Life Sci. 2007 Apr 24;80(20):1821-31. Epub 2007 Feb 3. PMID: 18257146
Article Published Date : Apr 24, 2007
Study Type : Human Study
Additional Links
Substances : Daidzein, Isoflavones
Diseases : Hot Flash, Menopausal Syndrome
[+]

DHEA is well tolerated and can reduce hot flashes. Jan 01, 2006

Pubmed Data : Support Cancer Ther. 2006 Jan 1;3(2):91-7. PMID: 18632445
Article Published Date : Jan 01, 2006
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Hot Flash
[+]

Flaxseed meal and flaxseed extract is effective in reducing menopausal symptoms without increasing blood levels of follicle stimulating hormone and estradiol, as well as in the endometrial thickness, and vaginal epithelial maturation value.Aug 31, 2012

Pubmed Data : J Med Food. 2012 Sep ;15(9):840-5. PMID: 22925074
Article Published Date : Aug 31, 2012
Study Type : Human Study
Additional Links
Substances : Flaxseed, Secoisolariciresinol diglucoside (SDG)
Diseases : Hot Flash, Menopausal Syndrome
[+]

Flaxseed therapy has a significant effect in managing hot flash in women not taking estrogen therapy. Jun 01, 2007

Pubmed Data : J Soc Integr Oncol. 2007 Summer;5(3):106-12. PMID: 17761129
Article Published Date : Jun 01, 2007
Study Type : Human Study
Additional Links
Substances : Flaxseed
Diseases : Estrogen Deficiency, Hot Flash
[+]

Folic acid supplementation may have therapeutic value in treating hot flushes in postmenopausal women.Sep 01, 2010

Pubmed Data : Gynecol Endocrinol. 2010 Sep ;26(9):658-62. PMID: 20230331
Article Published Date : Sep 01, 2010
Study Type : Human Study
Additional Links
Diseases : Hot Flash
[+]

Genistein appears to have a positive effect on hot flushes without a negative impact on endometrial thickness in early postmenopausal women.Jul 01, 2004

Pubmed Data : Menopause. 2004 Jul-Aug;11(4):400-4. PMID: 15243277
Article Published Date : Jul 01, 2004
Study Type : Human Study
Additional Links
Substances : Genistein
Diseases : Hot Flash, Postmenopausal Disorders
[+]

Genistein reduces vasomotor symptoms, e.g. hot flush, within postmenopausal women.Jul 01, 2007

Pubmed Data : Menopause. 2007 Jul-Aug;14(4):648-55. PMID: 17251874
Article Published Date : Jul 01, 2007
Study Type : Human Study
Additional Links
Substances : Genistein
Diseases : Hot Flash, Postmenopausal Disorders
[+]

Genistein significantly decreases hot flash symptoms in healthy postmenopausal women.Feb 01, 2011

Pubmed Data : Maturitas. 2011 Feb;68(2):189-96. Epub 2010 Dec 15. PMID: 21163595
Article Published Date : Feb 01, 2011
Study Type : Human Study
Additional Links
Substances : Genistein
Diseases : Hot Flash, Postmenopausal Disorders
[+]

Health-care providers should consider Valerian to be effective for menopausal women with hot flashes.Dec 31, 2017

Pubmed Data : Women Health. 2018 03 ;58(3):297-304. Epub 2017 Mar 17. PMID: 28278010
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Substances : Valerian
Diseases : Hot Flash, Menopausal Syndrome
[+]

Honey and bee pollen improve menopausal symptoms in breast cancer patients receiving antihormonal treatment.Jun 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Clin Oncol. 2015 Jul ;3(4):869-874. Epub 2015 May 4. PMID: 26171198
Article Published Date : Jun 30, 2015
Study Type : Human Study
Additional Links
Substances : Bee Pollen, Honey
Diseases : Hot Flash, Menopausal Syndrome
[+]

Hypericum perforatum (syn. St.John's wort) improves hot flashes and quality of life in perimenopausal women. Feb 01, 2005

Pubmed Data : J Adv Nurs. 2005 Feb;49(3):234-44. PMID: 19194342
Article Published Date : Feb 01, 2005
Study Type : Human Study
Additional Links
Substances : St. Johns Wort
Diseases : Hot Flash, Perimenopausal Syndrome, Quality of Life: Poor
[+]

In the active treatment group, 65% responded with a reduction in hot flashes compared with 38% in the placebo group.Jun 01, 2005

Pubmed Data : Climacteric. 2005 Jun ;8(2):162-70. PMID: 16096172
Article Published Date : Jun 01, 2005
Study Type : Human Study
Additional Links
Substances : Pollen: Flower
Diseases : Hot Flash
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Licorice seems more effective than HRT in improving hot flash duration, but that HRT can reduce the duration and severity of hot flashes more than licorice. Dec 31, 2013

Pubmed Data : Health Care Women Int. 2014 Jan ;35(1):87-99. Epub 2013 May 10. PMID: 23663094
Article Published Date : Dec 31, 2013
Study Type : Human Study
Additional Links
Substances : Licorice
Diseases : Hot Flash, Menopausal Syndrome
Additional Keywords : Hormone Replacement Therapy, Natural Substances Versus Drugs, Phytotherapy
[+]

Men treated for metastatic prostate cancer with anti-androgen therapy commonly experience andropause symptoms.May 09, 2011

Pubmed Data : Cancer Nurs. 2011 May 9. Epub 2011 May 9. PMID: 21558849
Article Published Date : May 09, 2011
Study Type : Human Study
Additional Links
Diseases : Andropause Syndrome, Gynecomastia, Hot Flash, Night Sweats
Problem Substances : Antiandrogen
Adverse Pharmacological Actions : Endocrine Disruptor
[+]

oral intake of curcumin and vitamin E significantly reduced hot flashes in postmenopausal women.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Complement Ther Med. 2020 Jan ;48:102267. Epub 2019 Nov 26. PMID: 31987231
Article Published Date : Dec 31, 2019
Study Type : Human Study
Additional Links
Substances : Curcumin, Vitamin E
Diseases : Hot Flash
[+]

Paced breathing could be beneficial in reducing hot flashes. Jan 31, 2013

Pubmed Data : Menopause. 2013 Feb ;20(2):179-84. PMID: 22990758
Article Published Date : Jan 31, 2013
Study Type : Human Study
Additional Links
Diseases : Hot Flash
Therapeutic Actions : Therapeutic Breathing
[+]

Pumpkin seed oil has beneficial properties in postmenopausal women. May 05, 2011

Pubmed Data : Climacteric. 2011 May 5. Epub 2011 May 5. PMID: 21545273
Article Published Date : May 05, 2011
Study Type : Human Study
Additional Links
Substances : Pumpkin Seed Oil/Meal
Diseases : HDL: Low, Hot Flash, Postmenopausal Disorders
[+]

Red clover isoflavones significantly reduce menopausal hot flush symptoms. Jul 25, 2002

Pubmed Data : Maturitas. 2002 Jul 25;42(3):187-93. PMID: 12161042
Article Published Date : Jul 25, 2002
Study Type : Human Study
Additional Links
Substances : Red Clover
Diseases : Hot Flash
[+]

Saffron is a safe and effective treatment in improving hot flashes and depressive symptoms in post-menopausal healthy women.Dec 31, 2017

Pubmed Data : Arch Gynecol Obstet. 2018 03 ;297(3):717-724. Epub 2018 Jan 13. PMID: 29332222
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Substances : Saffron
Diseases : Depression, Hot Flash
Pharmacological Actions : Antidepressive Agents
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Sage and alfalfa extracts are effective in reducing menopausal symptoms.May 01, 1998

Pubmed Data : Minerva Ginecol. 1998 May;50(5):207-11. PMID: 9677811
Article Published Date : May 01, 1998
Study Type : Human Study
Additional Links
Substances : Alfalfa, Sage
Diseases : Hot Flash, Menopausal Syndrome
[+]

The application of oral evening primrose oil led to a improvement in hot flash frequency, severity and duration. Oct 31, 2013

Pubmed Data : Arch Gynecol Obstet. 2013 Nov ;288(5):1075-9. Epub 2013 Apr 27. PMID: 23625331
Article Published Date : Oct 31, 2013
Study Type : Human Study
Additional Links
Substances : Evening Primrose Oil
Diseases : Hot Flash, Postmenopausal Disorders
Additional Keywords : Phytotherapy, Plant Extracts
[+]

The effect of evening primrose oil capsule on hot flashes and night sweats in postmenopausal women.Mar 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Menopausal Med. 2021 Apr ;27(1):8-14. PMID: 33942584
Article Published Date : Mar 31, 2021
Study Type : Human Study
Additional Links
Substances : Evening Primrose Oil
Diseases : Hot Flash, Postmenopausal Disorders
[+]

The use of lavender aromatherapy reduced menopause flushing in this study.Aug 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Chin Med Assoc. 2016 Sep ;79(9):489-92. Epub 2016 Jul 4. PMID: 27388435
Article Published Date : Aug 31, 2016
Study Type : Human Study
Additional Links
Substances : Lavender: Essential Oil
Diseases : Hot Flash, Menopausal Syndrome
Therapeutic Actions : Aromatherapy
[+]

Urtica dioica can decrease menopausal hot flashes and increase the quality of life of postmenopausal women.May 31, 2019

Pubmed Data : Complement Ther Med. 2019 Jun ;44:166-173. Epub 2019 Apr 4. PMID: 31126551
Article Published Date : May 31, 2019
Study Type : Human Study
Additional Links
Substances : Nettle
Diseases : Hot Flash, Menopausal Syndrome
Therapeutic Actions : Acupuncture
[+]

Vitex agnus can be considered as an effective and well tolerated treatment for the relief of symptoms of mild and moderate PMS.Jan 01, 2012

Pubmed Data : Acta Med Iran. 2012 ;50(2):101-6. PMID: 22359078
Article Published Date : Jan 01, 2012
Study Type : Human Study
Additional Links
Substances : Vitex Agnus
Diseases : Hot Flash, Premenstrual syndrome
Additional Keywords : Phytotherapy
[+]

Women treated with a fresh sage preparation experienced a significant decrease in the number and severity of hot flashes over an eight-week study period.Jun 01, 2011

Pubmed Data : Adv Ther. 2011 Jun ;28(6):490-500. Epub 2011 May 16. PMID: 21630133
Article Published Date : Jun 01, 2011
Study Type : Human Study
Additional Links
Substances : Sage
Diseases : Hot Flash
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Combined extract of Leonurus japonicus, Eclipta prostrata and Pueraria lobata improved hot flashes and depression.Jan 17, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Foods. 2021 Jan 18 ;10(1). Epub 2021 Jan 18. PMID: 33477405
Article Published Date : Jan 17, 2021
Study Type : Animal Study
Additional Links
Substances : Kudzu, Motherwort
Diseases : Depression, Hot Flash
Pharmacological Actions : Antidepressive Agents
[+]

Black Cohosh reduces hot flash symptoms in women. Apr 01, 2008

Pubmed Data : Ginekol Pol. 2008 Apr;79(4):287-96. PMID: 18592868
Article Published Date : Apr 01, 2008
Study Type : Review
Additional Links
Substances : Black Cohosh
Diseases : Hot Flash
[+]

Evening primrose oil in management of female ailments.Jul 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Menopausal Med. 2019 Aug ;25(2):74-82. Epub 2019 Aug 5. PMID: 31497576
Article Published Date : Jul 31, 2019
Study Type : Review
Additional Links
Substances : Evening Primrose Oil
Diseases : Gestational Diabetes, Hot Flash, Mastalgia, Premenstrual syndrome
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Malondialdehyde Down-regulation
[+]

Genistein is therapeutic in reducing hot flash symptoms. Sep 01, 2006

Pubmed Data : Menopause. 2006 Sep-Oct;13(5):831-9. PMID: 16932241
Article Published Date : Sep 01, 2006
Study Type : Review
Additional Links
Substances : Genistein
Diseases : Hot Flash
[+]

Homeopathic treatment for hot flushes in menopausal women is effective. Jan 01, 2008

Pubmed Data : Homeopathy. 2008 Jan;97(1):10-5. PMID: 18194760
Article Published Date : Jan 01, 2008
Study Type : Review
Additional Links
Diseases : Hot Flash
Therapeutic Actions : Homeopathic Treatment
Additional Keywords : Plant Extracts

Copyright: roboriginal / 123RF Stock Photo

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