Glioblastoma

Name	AC	CK
Curcumin	29	55
Cannabinoids	12	26
Cannabidiol	12	24
Delta-tetrahydrocannabinol (THC)	5	21
Beta-Elemene	9	19
Demethoxycurcumin	6	18
Thymoquinone	6	18
Bisdemethoxycurcumin	3	13
Berberine	8	11
Flavonoids	11	11
Ginsenosides	8	11
Antineoplastons	1	10
Curcuminoids	1	10
Honokiol	8	10
Resveratrol	5	10
Antineoplaston AS2-1 (4:1 mixture of phenylacetic acid and phenylacetylglutamine)	2	9
Shikonin	4	9
Cordyceps Militaris	3	7
Fucoxanthin	3	7
Myricetin	3	7
Pterostilbene	2	7
Sulforaphane	6	7
Genistein	5	6
Luteolin	6	6
Olive Oil	2	6
Paeoniflorin	4	6
Quercetin	5	6
Vitamin C	4	6
Xanthohumol	6	6
Astaxanthin	4	5
EGCG (Epigallocatechin gallate)	5	5
Melatonin	5	5
Piperlongumine	3	5
Rutin	4	5
Asiatic Acid	3	4
Bee Venom	3	4
Benzyl isothiocyanate	3	4
Biochanin A	3	4
Carnosine	4	4
Cucurbitacin B	3	4
Elecampane	4	4
Emodin	3	4
Magnolol	3	4
Mulberry	4	4
Naringenin	4	4
Olive leaf extract	4	4
Phenethyl isothiocyanate	3	4
Turmeric	3	4
Ursolic Acid	2	4
Verbascoside	4	4
Vitamin D	2	4
acetyl-11-keto-beta-boswellic acid	3	4
Apigenin	3	3
Carrot	2	3
Coenzyme Q10	2	3
Diosmin	2	3
Ellagic Acid	2	3
Nobiletin	2	3
Polyphenols	3	3
Reishi Mushroom	2	3
Salvia miltiorrhiza	2	3
Silibinin	3	3
Sinomenine	2	3
Vitamin C: Intravenous	1	3
Zerumbone	3	3
Ashwagandha	1	2
Bacopa	2	2
Bee Propolis	2	2
Berbamine	2	2
Betulinic acid	2	2
Bloodroot	1	2
Cannabis	2	2
Carnosol	2	2
Celastrol	2	2
Chrysin	2	2
Citrus naringin	2	2
Crocetin	1	2
Gingerol	2	2
Ginkgo biloba	2	2
Green Tea	1	2
Harmine	2	2
Lysine	1	2
Mushrooms: All	1	2
NAC (N-acetyl-L-cysteine)	1	2
Oleanolic acid	1	2
Oleuropein	2	2
Phloretin	2	2
Piperine	2	2
Proline	1	2
Red Clover	2	2
Rosemary	2	2
Rosmarinic acid	1	2
Sage	2	2
Tanshinone IIA	2	2
Urolithin A	1	2
Valerian	1	2
Allicin	1	1
Alpha-Lipoic Acid	1	1
Andrographolide	1	1
Anthocyanins	1	1
Apple	1	1
Arctigenin	1	1
Artesunate	1	1
Beta-Caryophyllene	1	1
Bitter Melon	1	1
Bufalin	1	1
Cannabigerol	1	1
Capsaicin	1	1
Carnosic Acid	1	1
Carvacrol	1	1
Cat's Claw	1	1
Chinese Skullcap	1	1
Chokeberry	1	1
Cranberry	1	1
Cyanidin 3-glucoside	1	1
Dates	1	1
Delphinidin	1	1
Dimethyl trisulfide (DMTS)	1	1
Diosgenin	1	1
Eriodictyol	1	1
Evodiamine	1	1
Feverfew	1	1
Fig	1	1
Fisetin	1	1
Formononetin	1	1
Frankincense	1	1
Galbanic Acid	1	1
Garcinia dulcis	1	1
Garlic	1	1
Gastrodin	1	1
Genipin	1	1
Ginger	1	1
Ginseng (Korean)	1	1
Goji	1	1
Gold (nanoparticles)	1	1
Guava	1	1
Guduchi	1	1
Hawthorn	1	1
Hemp Seed	1	1
Homeopathic Medicine: All	1	1
Horse Chestnut	1	1
Hydrogen Water	1	1
Hydroxytyrosol	1	1
Hyperforin	1	1
IP6	1	1
Infection/Infectitious Agent Byproducts (Beneficial)	1	1
Inositol Hexaphosphate	1	1
Isoflavones	1	1
Kaempferol	1	1
Kefir	1	1
Kiwifruit	1	1
Lichens	1	1
Lithospermum erythrorhizon	1	1
Loquat	1	1
Lotus	1	1
Lycopene	1	1
Mangiferin	1	1
Mangosteen	1	1
Marijuana	1	1
Morelloflavone	1	1
Organosulfur Compounds	1	1
Parsley	1	1
Parthenolide	1	1
Phellinus Linteus	1	1
Polyunsaturated Fatty Acids (PUFAs)	1	1
Propolis: Bee	1	1
Psychedelics:All	1	1
Punicic acid	1	1
Rock-rose	1	1
Royal Jelly	1	1
Saffron	1	1
Saikosaponin	1	1
Silymarin	1	1
St. Johns Wort	1	1
Tangeretin	1	1
Tannic Acid	1	1
Thistle	1	1
Venom: Toad	1	1
Vitamin B-6	1	1
Vitamin B12	1	1
Vitamin E	1	1
Vitamin E: Gamma-tocotrienol	1	1
Vitexins	1	1
Zataria multiflora	1	1
cottonseed oil (gossypol)	1	1

Name	AC	CK
Cell Phone Exposure	2	30
Simian virus 40 (SV40)	1	10
Glyphosate	1	1

Name	AC	CK
Dietary Modification: Low Carbohydrate/Ketogenic	4	25
Hyperbaric Treatment	3	14
Ultrasound	1	10
Photodynamic therapy	4	4
Photobiomodulation	1	1
Ultrasound therapy	1	1

Name	AC	CK
Electromagnetic Field Harms	5	55
Electromagnetic Radiation	4	45
Mobile Phone Radiation	3	40
Microwave Radiation	2	30
Radiotherapy	2	11
Chemotherapy	1	10
Biopsy: Various Tissue	1	1
Vaccination: All	1	1
Vaccination: Varicella (Chicken pox)	1	1

Click here to read the entire abstract

Pubmed Data : Neuroepidemiology. 2013 ;40(2):101-8. Epub 2012 Oct 24. PMID: 23095687

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Rare Tumors. 2014 Jul 30 ;6(3):5350. Epub 2014 Aug 8. PMID: 25276320

Article Published Date : Jul 30, 2014

Study Type : Human Study

Additional Links

Diseases : Glioblastoma, Glioblastoma Multiforme

Additional Keywords : Cell Phones, Cellular Phones and Cancers, electromagnetic fields, electromagnetic frequencies, electromagnetic radiation, EMF, Radio Frequency Electromagnetic Radiation Exposure

Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation, Microwave Radiation, Mobile Phone Radiation

Problem Substances : Cell Phone Exposure

[+]

Ketogenic diet treatment as adjuvant to standard treatment of glioblastoma multiforme.Dec 31, 2018

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Pubmed Data : Ther Adv Med Oncol. 2019 ;11:1758835919853958. Epub 2019 Jun 21. PMID: 31258628

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Transl Med. 2016 Jun 15 ;8(343):343re2. PMID: 27306666

Olive oil compounds inhibit the effect of the chronic inflammatory microenvironment on glioblastoma progression.Aug 31, 2015

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Pubmed Data : J Nutr Biochem. 2015 Sep 1. Epub 2015 Sep 1. PMID: 26410343

Article Published Date : Aug 31, 2015

Study Type : Human In Vitro

Additional Links

Substances : Olive Oil

Diseases : Glioblastoma

Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Click here to read the entire abstract

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Pubmed Data : Exp Oncol. 2016 Mar ;38(1):54-6. PMID: 27031721

Article Published Date : Feb 29, 2016

Study Type : Animal Study

Additional Links

Substances : Green Tea, Lysine, Proline, Vitamin C

Diseases : Glioblastoma

Pharmacological Actions : Chemotherapeutic

[+]

Additive antiangiogenesis effect of ginsenoside Rg3 with low-dose metronomic temozolomide on rat glioma cells both in vivo and in vitro.Feb 12, 2016

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[+]

MicroRNA 145 enhances chemosensitivity of glioblastoma stem cells to demethoxycurcumin.Dec 31, 2018

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Pterostilbene treatment suppressed glioma stem cell development via negatively modulating GRP78 signaling.Apr 30, 2015

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Pubmed Data : J Nutr Biochem. 2015 May ;26(5):466-75. Epub 2015 Jan 19. PMID: 25736407

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Pubmed Data : J Neurosurg. 2017 Jan 6:1-12. Epub 2017 Jan 6. PMID: 28059653

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Pubmed Data : Int J Nanomedicine. 2017 ;12:1369-1384. Epub 2017 Feb 17. PMID: 28260885

Article Published Date : Dec 31, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Glioblastoma

Pharmacological Actions : Antineoplastic Agents, Apoptotic

Additional Keywords : Cancer Stem Cells, Liposomal Curcumin

[+]

The in vivo administration of microencapsulated cannabinoids efficiently reduces tumor growth.Dec 31, 2012

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Pubmed Data : PLoS One. 2013 ;8(1):e54795. Epub 2013 Jan 22. PMID: 23349970

Article Published Date : Dec 31, 2012

Study Type : Animal Study

Additional Links

Substances : Cannabidiol, Cannabinoids , Delta-tetrahydrocannabinol (THC)

Diseases : Glioblastoma Multiforme

Pharmacological Actions : Angiogenesis Inhibitors, Antiproliferative , Apoptotic

[+]

The present data demonstrate that β-2-himachalen-6-ol is a potential multi-mechanistic chemotherapeutic drug.May 26, 2016

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Pubmed Data : J Ethnopharmacol. 2016 May 27. Epub 2016 May 27. PMID: 27240746

Article Published Date : May 26, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Carrot

Diseases : Breast Cancer: Triple Negative , Colorectal Cancer, Glioblastoma, Melanoma, Non-Small-Cell Lung Carcinoma

Pharmacological Actions : Anti-metastatic, Apoptotic

[+]

These results suggest that both astaxanthin and adonixanthin have potential as treatments for glioblastoma.Sep 17, 2020

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Pubmed Data : Mol Carcinog. 2017 Mar ;56(3):1088-1099. Epub 2016 Oct 4. PMID: 27649384

Article Published Date : Feb 28, 2017

Study Type : In Vitro Study

Additional Links

Substances : Anthocyanins, Delphinidin

Diseases : Glioblastoma

Pharmacological Actions : Anti-metastatic

[+]

Anti-brain cancer activity of chloroform and hexane extracts of Tinospora cordifolia.Dec 31, 2018

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Pubmed Data : Ann Neurosci. 2019 Jan ;26(1):10-20. Epub 2019 Jan 1. PMID: 31975767

Article Published Date : Dec 31, 2018

Study Type : In Vitro Study

Additional Links

Substances : Guduchi

Diseases : Glioblastoma, Neuroblastoma

Pharmacological Actions : Anti-metastatic, Antiproliferative

[+]

Anti-oxidants may have synergistic effects with temozolomide.Jun 19, 2018

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Pubmed Data : Medicines (Basel). 2018 Jun 20 ;5(2). Epub 2018 Jun 20. PMID: 29925764

Article Published Date : Jun 19, 2018

Study Type : In Vitro Study

Additional Links

Substances : Alpha-Lipoic Acid, Melatonin, Vitamin D

Diseases : Glioblastoma

Pharmacological Actions : Chemosensitizer

Additional Keywords : Chemotherapeutic Synergy: Temozolomide

[+]

Anti-proliferative potential of cynaroside and orientin.Nov 20, 2023

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Pubmed Data : Oncol Rep. 2016 Apr ;35(4):2089-96. Epub 2016 Jan 19. PMID: 26781422

Article Published Date : Mar 31, 2016

Study Type : In Vitro Study

Additional Links

Substances : Benzyl isothiocyanate

Diseases : Glioblastoma

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest

Additional Keywords : Gene Expression Regulation, Isothiocyanates

[+]

Benzyl isothiocyanate induces apoptosis of GBM 8401 human brain glioblastoma multiforms cells.Nov 30, 2016

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Pubmed Data : Environ Toxicol. 2016 Dec ;31(12):1751-1760. Epub 2015 Sep 7. PMID: 28675694

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Pubmed Data : Cancer Cell Int. 2020 Dec 9 ;20(1):592. Epub 2020 Dec 9. PMID: 33298057

Article Published Date : Dec 08, 2020

Study Type : In Vitro Study

Additional Links

Substances : Berberine

Diseases : Glioblastoma

Pharmacological Actions : Chemosensitizer

Additional Keywords : Chemotherapeutic Synergy: Temozolomide

[+]

Beta-Elemene enhances the efficacy of gefitinib on glioblastoma multiforme cells.Sep 30, 2016

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Pubmed Data : Oncol Rep. 2012 Oct ;28(4):1435-42. Epub 2012 Jul 27. PMID: 22842701

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Pubmed Data : J Neurooncol. 2005 Aug;74(1):31-40. PMID: 16078104

Article Published Date : Aug 01, 2005

Study Type : In Vitro Study

Additional Links

Substances : Marijuana

Diseases : Glioblastoma Multiforme

[+]

Cannabinoids were shown to be of potential use for therapeutic approaches of glioblastoma.May 04, 2016

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Pubmed Data : Cell Adh Migr. 2016 May 5:0. Epub 2016 May 5. PMID: 27149140

Article Published Date : May 04, 2016

Study Type : In Vitro Study

Additional Links

Substances : Cannabinoids

Diseases : Glioblastoma

Pharmacological Actions : Anti-metastatic

[+]

Cannabis biomolecule effects on cancer cells and cancer stem cells: cytotoxic, anti-proliferative, and anti-migratory activities.Jan 23, 2022

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Pubmed Data : Biomolecules. 2022 03 24 ;12(4). Epub 2022 Mar 24. PMID: 35454080

Carnosol led to p53 reactivation in the U87MG human glioblastoma cell line.Apr 30, 2016

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Pubmed Data : Int J Biochem Cell Biol. 2016 May ;74:95-108. Epub 2016 Mar 3. PMID: 26939786

Article Published Date : Apr 30, 2016

Study Type : In Vitro Study

Additional Links

Substances : Carnosol

Diseases : Glioblastoma

Pharmacological Actions : Antineoplastic Agents, Tumor Suppressor Protein p53 Upregulation

Additional Keywords : Chemotherapeutic Synergy: Temozolomide, Reactivation Of Tumor Suppressor Gene

[+]

Cat's claw chemotypes showed different selectivity against human malignant cells.Aug 01, 2016

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Pubmed Data : J Ethnopharmacol. 2016 Aug 2 ;189:90-8. Epub 2016 May 13. PMID: 27180878

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Pubmed Data : Sci Rep. 2020 12 3 ;10(1):21127. Epub 2020 Dec 3. PMID: 33273550

Article Published Date : Jan 02, 2020

Study Type : In Vitro Study

Additional Links

Substances : Bacopa, Bee Propolis

Diseases : Glioblastoma

Pharmacological Actions : Antiproliferative

Additional Keywords : Natural Substance Synergy

[+]

Chinese skullcap (S. baicalensis) has anticancer activity on human malignant brain tumor cells. Aug 16, 2006

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Pubmed Data : BMC Complement Altern Med. 2006 Aug 16;6:27. PMID: 16914050

Article Published Date : Aug 16, 2006

Study Type : In Vitro Study

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Substances : Chinese Skullcap

Diseases : Brain Cancer, Glioblastoma Multiforme

[+]

Chrysin suppresses proliferation, migration, and invasion in glioblastoma cell lines.Dec 31, 2017

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Pubmed Data : Drug Des Devel Ther. 2018 ;12:721-733. Epub 2018 Apr 3. PMID: 29662304

Article Published Date : Dec 31, 2017

Study Type : In Vitro Study

Additional Links

Substances : Chrysin

Diseases : Glioblastoma

Pharmacological Actions : Anti-metastatic, Antiproliferative , Chemotherapeutic, Nrf2 activation

[+]

Co-administration of cytotoxic agents together with CBD increases drug uptake and potentiates cytotoxic activity in human glioma cells.Dec 31, 2012

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Pubmed Data : Carcinogenesis. 2013 Jan ;34(1):48-57. Epub 2012 Oct 18. PMID: 23079154

Article Published Date : Dec 31, 2012

Study Type : In Vitro Study

Additional Links

Substances : Cannabidiol

Diseases : Glioblastoma Multiforme

Pharmacological Actions : Chemosensitizer

Additional Keywords : Natural Substance/Drug Synergy

[+]

Coenzyme Q10 acts as sensitizer for cytotoxic therapies.May 17, 2018

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Pubmed Data : Radiother Oncol. 2018 May 18. Epub 2018 May 18. PMID: 29784452

Article Published Date : May 17, 2018

Study Type : In Vitro Study

Additional Links

Substances : Coenzyme Q10

Diseases : Glioblastoma

Pharmacological Actions : Chemosensitizer, Radiosensitizer

Additional Keywords : Chemotherapeutic Synergy: Temozolomide

[+]

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Pubmed Data : Biomed Res Int. 2022 ;2022:4740246. Epub 2022 Jun 10. PMID: 35722462

Pubmed Data : Neurochem Res. 2007 Dec;32(12):2103-13. Epub 2007 Jun 12. PMID: 17562168

Article Published Date : Dec 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Brain Cancer, Glioblastoma

[+]

Curcumin potentiates the potent antitumor activity of ACNU against glioblastoma.Dec 31, 2016

[+]

diosgenin showed anti-tumor effects in glioblastoma cells.Sep 30, 2020

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Pubmed Data : Neurochem Res. 2020 Oct ;45(10):2336-2351. Epub 2020 Jul 18. PMID: 32683533

Article Published Date : Sep 30, 2020

Study Type : In Vitro Study

Additional Links

Substances : Diosgenin

Diseases : Glioblastoma

Pharmacological Actions : Anti-Angiogenic, Antineoplastic Agents, Antiproliferative , Apoptotic, Bcl-2 protein down-regulation, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor

[+]

Diosmin induces caspase-dependent apoptosis in human glioblastoma cells.Dec 31, 2018

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Ficus carica latex prevents invasion through induction of let-7d expression in GBM cell lines.Feb 28, 2015

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Pubmed Data : Cell Mol Neurobiol. 2015 Mar ;35(2):175-87. Epub 2014 Sep 12. PMID: 25212824

Article Published Date : Feb 28, 2015

Study Type : In Vitro Study

Additional Links

Substances : Fig

Diseases : Cancer Metastasis, Glioblastoma

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic

Additional Keywords : Phytotherapy, Plant Extracts

[+]

Flavonoids synergistically enhance the anti-glioblastoma effects of chemotherapeutic drugs.Jan 06, 2021

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Pubmed Data : Biomolecules. 2021 12 7 ;11(12). Epub 2021 Dec 7. PMID: 34944485

Article Published Date : Jan 06, 2021

Study Type : In Vitro Study

Additional Links

Substances : Chrysin, EGCG (Epigallocatechin gallate), Flavonoids, Formononetin, Quercetin, Rutin, Silibinin

Diseases : Cancers: Drug Resistant, Glioblastoma

Pharmacological Actions : Antiproliferative , Apoptotic

Additional Keywords : Natural Substance/Drug Synergy

[+]

Focused ultrasound induced immunomodulation effects can be harnessed to current and developing immunotherapy approaches.Dec 31, 2015

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Substances : cottonseed oil (gossypol)

Diseases : Cancers: Drug Resistant, Glioblastoma

Pharmacological Actions : Antiproliferative

[+]

Harmine hydrochloride inhibits Akt phosphorylation and depletes the pool of cancer stem-like cells of glioblastoma.Feb 28, 2013

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Pubmed Data : J Neurooncol. 2013 Mar ;112(1):39-48. Epub 2013 Feb 8. PMID: 23392846

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Pubmed Data : Environ Toxicol. 2017 Jun 15. Epub 2017 Jun 15. PMID: 28618133

Article Published Date : Jun 14, 2017

Study Type : In Vitro Study

Additional Links

Substances : Phellinus Linteus

Diseases : Glioblastoma

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest

[+]

Hono-Mag exerts a synergistic anti-tumor effect by inhibiting cell proliferation and inducing autophagy and apoptosis in human GBM cells.Apr 10, 2016

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Pubmed Data : Oncotarget. 2016 Apr 11. Epub 2016 Apr 11. PMID: 27074557

Article Published Date : Apr 10, 2016

Study Type : In Vitro Study

Additional Links

Substances : Honokiol, Magnolol

Diseases : Glioblastoma

Pharmacological Actions : Antiproliferative , Apoptotic, Autophagy Up-regulation

Additional Keywords : Natural Substance Synergy, Superiority of Natural Substances versus Drugs

[+]

Honokiol can repress human glioma growth by inducing apoptosis and cell cycle arrest in tumor cells.May 14, 2016

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Pubmed Data : Phytomedicine. 2016 May 15 ;23(5):517-27. Epub 2016 Mar 9. PMID: 27064011

Article Published Date : May 14, 2016

Study Type : In Vitro Study

Additional Links

Substances : Honokiol

Diseases : Glioblastoma Multiforme, Glioma

Pharmacological Actions : Apoptotic, Cell cycle arrest

[+]

Honokiol eliminates glioma/glioblastoma stem cell-like cells and inhibits tumor progression.Dec 25, 2018

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Pubmed Data : Pharmaceutics. 2023 Jan 29 ;15(2). Epub 2023 Jan 29. PMID: 36839769

Article Published Date : Jan 28, 2023

Study Type : In Vitro Study

Additional Links

Substances : Honokiol

Diseases : Glioblastoma

Pharmacological Actions : Antiproliferative

[+]

Hyperbaric oxygen therapy as adjunctive strategy in treatment of glioblastoma multiforme.Dec 31, 2017

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Pubmed Data : BMC Neurosci. 2019 12 23 ;20(1):63. Epub 2019 Dec 23. PMID: 31870319

Article Published Date : Jan 22, 2019

Study Type : In Vitro Study

Additional Links

Substances : Melatonin

Diseases : Glioblastoma

Pharmacological Actions : Apoptotic, Autophagy Inhibitors

[+]

Inhibition of growth of U87MG human glioblastoma cells by Usnea longissima Ach.Dec 31, 2018

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Pubmed Data : An Acad Bras Cienc. 2019 ;91(3):e20180994. Epub 2019 Oct 7. PMID: 31596391

Article Published Date : Dec 31, 2018

Study Type : In Vitro Study

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Substances : Lichens

Diseases : Glioblastoma, Oxidative Stress

Pharmacological Actions : Antioxidants, Antiproliferative

Additional Keywords : Plant Extracts

[+]

Inhibition of lipid droplet accumulation is an effective way to enhance the chemotherapeutic effect of curcumin against glioblastoma multiforme.Jan 03, 2016

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Pubmed Data : Eur J Pharm Biopharm. 2016 Jan 4. Epub 2016 Jan 4. PMID: 26763536

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Pubmed Data : Oncol Rep. 2018 Oct 1. Epub 2018 Oct 1. PMID: 30272350

Article Published Date : Sep 30, 2018

Study Type : In Vitro Study

Additional Links

Substances : Mangiferin

Diseases : Glioblastoma

Pharmacological Actions : Radiosensitizer

[+]

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Pubmed Data : Mol Carcinog. 2016 Jan ;55(1):77-89. Epub 2014 Dec 31. PMID: 25557841

Article Published Date : Dec 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Flavonoids, Mulberry

Diseases : Glioblastoma

Pharmacological Actions : Apoptotic

Additional Keywords : Cancer Stem Cells

[+]

Myricetin is a multi-targeted drug that has potent anti-migratory and anti-invasive effects on glioblastoma multiforme cells.Jun 09, 2018

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Pubmed Data : CNS Neurol Disord Drug Targets. 2018 Jun 10. Epub 2018 Jun 10. PMID: 29886836

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Pubmed Data : BMC Pharmacol Toxicol. 2020 Jun 23 ;21(1):46. Epub 2020 Jun 23. PMID: 32576255

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Pubmed Data : Phytother Res. 2015 Nov 12. Epub 2015 Nov 12. PMID: 26560814

Article Published Date : Nov 11, 2015

Study Type : In Vitro Study

Additional Links

Substances : Nobiletin

Diseases : Glioblastoma Multiforme

Pharmacological Actions : Anti-metastatic, Antiproliferative , Cell cycle arrest, Cyclin D1 Down-Regulation

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Nuciferine inhibits the progression of glioblastoma.Mar 28, 2019

Onopordum acanthium is considered a promising plant for antitumour and immune-related activity.Jun 30, 2015

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Pubmed Data : Pak J Pharm Sci. 2015 Jul ;28(4):1225-32. PMID: 26142501

Article Published Date : Jun 30, 2015

Study Type : In Vitro Study

Additional Links

Substances : Thistle

Diseases : Glioblastoma

Pharmacological Actions : Apoptotic

Additional Keywords : Plant Extracts

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View the Evidence: 390 Abstracts with Glioblastoma Research

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Antineoplasto exhibits antitumor activity against malignant brain tumors.Jan 01, 1995

Beta-elemene might provide a survival benefit in patients with glioblastoma.Dec 31, 2015

CBD is a well supported co-medication and seems to prolong the survival of patients with glioblastoma multiforme.Apr 30, 2021

Changes in cerebral metabolism during ketogenic diet in patients with primary brain tumorsJan 09, 2017

Curcumin induces programmed cell death in human malignant gliobastoma cells - Article 2. Oct 16, 2006

Decreased survival of glioma cases is associated with long-term and high cumulative use of mobile phones.Jan 01, 2013

Decreased survival of glioma patients with astrocytoma grade IV (glioblastoma multiforme) associated with long-term use of mobile and cordless phones.Oct 15, 2014

Delta9-tetrahydrocannabinol administration led to the inhibition of the VEGF Pathway in Two Patients with Glioblastoma Multiforme.Aug 14, 2004

Hyperbaric oxygen therapy with chemotherapy was a feasible and promising treatment modality for patients with glioblastoma.Nov 16, 2016

In an Australian multicenter study, a significant increasing incidence in glioblastoma multiforme was observed from 2000-2008, particularly after 2006. Rising trends in incidence were also seen for meningioma in the total male population.Jan 01, 2011

In this study, p53 gene expression in the peripheral zone of glioblastoma was increased in 65% of patients who used cell phones more than 3 hours a day and that this increase was significantly correlated with shorter overall survival time.Jul 30, 2014

Ketogenic diet treatment as adjuvant to standard treatment of glioblastoma multiforme.Dec 31, 2018

Oral treatment with micellar curcuminoids led to quantifiable concentrations of total curcuminoids in glioblastomas.Jun 23, 2016

Pineal calcification appears to be associated with primary brain tumors.Jul 26, 2016

Pulsed ultrasound has the potential to optimize chemotherapy or phytochemical delivery in the brain.Jun 14, 2016

SV40 is associated significantly with brain tumors, bone cancers, malignant mesothelioma, and non-Hodgkin's lymphoma.Jun 01, 2003

The gut-brain-axis: A positive relationship between gut microbial dysbiosis and glioblastoma brain tumour.May 14, 2024

There is an increased risk for grade IV astrocytoma associated with occupational extremely low-frequency electromagnetic fields.May 01, 2017

This study presents evidence of significant and progressive treatment-associated structural brain changes in patients with glioblastoma treated with chemoradiation.Aug 24, 2015

Cordycepin inhibited migration of human glioblastoma cells by affecting lysosomal degradation and protein phosphatase activation.Dec 28, 2016

Effects of thymoquinone and the curcumin analog EF-24 on the activity of the enzyme paraoxonase-1 in human glioblastoma cells U87MG.Nov 30, 2024

Elevated CB2 receptor expression was identified in glioblastoma cells.Jun 29, 2009

Fucoxanthin activates apoptosis and suppresses invasion and migration glioblastoma cells.Sep 30, 2016

Magnetic fields may upregulate chemoresistance in human glioblastoma.Jan 01, 2018

Olive oil compounds inhibit the effect of the chronic inflammatory microenvironment on glioblastoma progression.Aug 31, 2015

Pluronic-based micelle encapsulation potentiates myricetin-induced cytotoxicity in human glioblastoma cells.Dec 31, 2015

Pterostilbene might be used to modulate two anticancer compounds in well-defined sets of GBM patients.Nov 07, 2016

Resveratrol may represent a new interesting therapeutic approach, in order to affect glioma stem cell proliferation and motility.Dec 31, 2016

Shikonin and temozolomide may constitute a powerful new tool for Glioblastoma treatment by reducing therapy resistance and tumor recurrence.Apr 10, 2017

The proapoptotic effect of cannabinoids on tumor cells is mediated by a ceramide dependent upregulation of the stress protein p8.Mar 31, 2006

These findings describe a mechanism by which THC can promote the autophagic death of human and mouse cancer cells.Apr 30, 2009

Thymoquinone could be useful as a potential chemotherapeutic agent in the management for brain tumours.Aug 11, 2010

Thymoquinone intensified temozolomide-induced apoptosis in U87MG cells.Apr 20, 2017

A quick response of advanced cancer to chemoradiation therapy with antineoplastons has been reported.May 01, 1998

Honokiol in glioblastoma recurrence: a case report.Dec 31, 2022

Hyperbaric oxygen therapy adjuvant chemotherapy and radiotherapy through inhibiting stemness in glioblastoma.Oct 11, 2023

Long-term survival and complete response of a patient with recurrent diffuse intrinsic brain stem glioblastoma multiforme has been reported.Sep 01, 2004

Management of glioblastoma multiforme in a patient treated with ketogenic metabolic therapy and modified standard of care: a 24-month follow-up.Dec 31, 2017

This case report highlights the benefits of intravenous vitamin C as a supportive therapy for patients with glioblastoma.Aug 29, 2018

Ursolic acid nanoparticles for glioblastoma therapy.May 31, 2023

20(S)-ginsenoside-Rg3 reverses temozolomide resistance and restrains epithelial-mesenchymal transition progression in glioblastoma.Dec 31, 2018

A nutrient mixture inhibited tumor weight and tumor burden by 53% and 48% respectively.Feb 29, 2016

Additive antiangiogenesis effect of ginsenoside Rg3 with low-dose metronomic temozolomide on rat glioma cells both in vivo and in vitro.Feb 12, 2016

Allosteric antagonist modulation of TRPV2 by piperlongumine impairs glioblastoma progression.May 25, 2021

Amauroderma rude could inhibit cancer cell survival and induce apoptosis, also there were fewer and smaller colonies than the untreated cells.Dec 31, 2012

Asiatic acid induces endoplasmic reticulum stress and apoptotic death in glioblastoma multiforme cellsOct 31, 2015

Benzyl isothiocyanate inhibits human brain glioblastoma multiforme GBM 8401 cells.Oct 31, 2018

Berberine induced senescence of human glioblastoma cells.Jan 31, 2015

Berberine inhibited angiogenesis in glioblastoma xenografts.Nov 30, 2018

Berberine significantly reduces tumor growth in vivo.Aug 18, 2016

Biochanin A sensitizes glioblastoma to temozolomide by inhibiting autophagy.Jan 31, 2022

Bisdemethoxycurcumin induces cell apoptosis and inhibits human brain glioblastoma.Jan 03, 2022

Cannabidiol enhanced the ability of THC to inhibit cell proliferation, induce cell cycle arrest and apoptosis.Dec 31, 2009

CBD induced a robust increase in ROS, which led to the inhibition of cell survival, phosphorylated (p)-AKT, self-renewal and a significant increase in the survival of GSC bearing mice.Dec 31, 2014

Combined acetyl-11-keto-β-boswellic acid and radiation treatment inhibited glioblastoma tumor cellsDec 31, 2017

Crocetin extracted from saffron shows antitumor effects in models of human glioblastoma.Jan 08, 2020

Cucurbitacin B induces inhibitory effects in glioblastoma multiforme.Feb 01, 2018

Curcumin Changes the Polarity of Tumor-Associated Microglia and Eliminates Glioblastoma.Aug 19, 2016

Curcumin enhanced the therapeutic response to TMZ in U87MG glioblastoma by enhancing apoptosis.Sep 30, 2014

Curcumin inhibits tumor growth and angiogenesis in glioblastoma xenografts.Aug 01, 2010

Demethoxycurcumin suppresses human brain glioblastoma multiforme GBM 8401 cell.May 22, 2021

Demethoxycurcumin was superior to temozolomide in the inhibition of the growth of glioblastoma stem cells in vivo.Oct 17, 2016

Diosmin inhibits glioblastoma growth through inhibition of autophagic flux.Sep 27, 2021

Effect of rosmarinic acid on cell proliferation, oxidative stress, and apoptosis pathways in an animal model of induced Glioblastoma multiforme.May 15, 2024

Effects of aloe emodin on U87MG glioblastoma cell growth.Oct 31, 2018

EGFR signaling-dependent inhibition of glioblastoma growth by ginsenoside Rh2.May 31, 2014

Ellagic acid may be beneficial for the treatment of glioblastoma.Jan 31, 2017

Genistein mediated upregulation of CHOP impeded C/EBPβ interaction with the IL-6 promoter, thus disturbing the angiogenic microenvironment which inhibited tumor proliferation.May 31, 2015

High doses of sodium ascorbate interfere with the expansion of glioblastoma multiforme cells in vitro and in vivo.Aug 31, 2019

Inhibition of glioblastoma progression by Urolithin A in vitro and in vivo.Nov 24, 2021

Local administration of shikonin improved the overall survival in orthotopic murine glioblastoma models with temozolomide resistance.Aug 06, 2023

Magnolol is a potential candidate for glioma treatment.May 31, 2018

Glioblastoma

View the Evidence:
390 Abstracts with Glioblastoma Research