Gastrointestinal Cancer

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28 Substances Researched for Gastrointestinal Cancer
NameACCKFocus
Grape110Locked
Vitamin D110Locked
Curcumin69Locked
Berberine33Locked
Allicin22Locked
Anthocyanins12Locked
Antineoplaston AS2-1 (4:1 mixture of phenylacetic acid and phenylacetylglutamine)12Locked
Artesunate12Locked
Dibenzoylmethane (DBM)12Locked
Ellagic Acid12Locked
Ginsenosides22Locked
Mistletoe12Locked
Pterostilbene22Locked
Quercetin12Locked
Sulforaphane12Locked
Tart Cherry12Locked
6-Shogaol11Locked
Emodin11Locked
Ginger11Locked
Gingerol 11Locked
Hawthorn11Locked
Kaempferol11Locked
Lotus 11Locked
Pistachio nut 11Locked
Probiotics11Locked
Red Marine Algae11Locked
Resveratrol11Locked
Seaweed: Brown 11Locked
5 Problem Substances Researched for Gastrointestinal Cancer
NameACCKFocus
Mass Market Vitamins110Locked
Proton-Pump Inhibitors110Locked
Sorbitol 110Locked
IGF-111Locked
Recombinant Bovine Growth Hormone (rBGH)11Locked
2 Problematic Actions Researched for Gastrointestinal Cancer
NameACCKFocus
Chemotherapy110Locked
Radiotherapy11Locked
Related Topics

Gastrointestinal Cancer is a Sub of the following Topic

View the Evidence:
40 Abstracts with Gastrointestinal Cancer Research

[+]

Chemotherapy does not appear to provide any benefit for metastatic cancer of the esophagus and gasto-esophageal junction.Jan 01, 2010

Pubmed Data : Cochrane Database Syst Rev. 2010;5:CD004063. Epub 2010 May 12. PMID: 20464727
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Diseases : Esophageal Cancer, Gastrointestinal Cancer
Anti Therapeutic Actions : Chemotherapy
[+]

Mass market antioxidant supplements may increase overall mortality from gastrointestinal cancers. Jun 30, 2008

Pubmed Data : Aliment Pharmacol Ther. 2008 Jun 30. Epub 2008 Jun 30. PMID: 18616690
Article Published Date : Jun 30, 2008
Study Type : Human Study
Additional Links
Diseases : Gastrointestinal Cancer
Problem Substances : Mass Market Vitamins
[+]

Sorbitol intolerance may be at the root of "functional" gastointestinal complaints.Jan 01, 1983

Pubmed Data : Gastroenterology. 1983 Jan;84(1):30-3. PMID: 6847853
Article Published Date : Jan 01, 1983
Study Type : Human Study
Additional Links
Diseases : Diarrhea, Gastrointestinal Cancer
Problem Substances : Sorbitol
[+]

Taking proton pump inhibitors is associated with a small excess of cause specific mortality.Jan 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMJ. 2019 05 29 ;365:l1580. Epub 2019 May 29. PMID: 31147311
Article Published Date : Jan 28, 2019
Study Type : Human Study
Additional Links
Diseases : All-Cause Mortality, Chronic Kidney Disease (CKD), Gastrointestinal Cancer
Additional Keywords : Risk Factors
Problem Substances : Proton-Pump Inhibitors
[+]

The dietary intake of table grape affects circulating miRNAs levels in healthy subjects.Oct 31, 2021

Pubmed Data : Mol Nutr Food Res. 2021 Nov ;65(21):e2100428. Epub 2021 Sep 21. PMID: 34495579
Article Published Date : Oct 31, 2021
Study Type : Human Study
Additional Links
Substances : Grape
Diseases : Gastrointestinal Cancer
Pharmacological Actions : Chemopreventive, MicroRNA modulator
[+]

Vitamin D supplementation significantly reduced the risk of relapse/death to approximately one-third in the highest quintile of serum PD-L1.Jun 08, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2021 Jun 9 ;13(6). Epub 2021 Jun 9. PMID: 34207794
Article Published Date : Jun 08, 2021
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Digestive System Cancer, Gastrointestinal Cancer
Pharmacological Actions : Chemotherapeutic
[+]

Spontaneous regression of liver metastases in neuroendocrine tumors of the abdomen.Jan 31, 1991

Pubmed Data : Ultraschall Med. 1991 Feb ;12(1):41-4. PMID: 2057755
Article Published Date : Jan 31, 1991
Study Type : Human: Case Report
Additional Links
Diseases : Gastrointestinal Cancer
Additional Keywords : Spontaneous Tumor Regression
[+]

Antineoplaston AS2-1 may have inhibitory effects against gastrointestinal cancer. Jan 01, 2005

Pubmed Data : Biomed Khim. 2005 ;51(1):48-52. PMID: 15850218
Article Published Date : Jan 01, 2005
Study Type : Animal Study
Additional Links
Substances : Antineoplaston AS2-1 (4:1 mixture of phenylacetic acid and phenylacetylglutamine)
Diseases : Gastrointestinal Cancer
[+]

Artesunate inhibits intestinal tumorigenesis through Inhibiting Wnt signalling.Jul 24, 2020

Pubmed Data : Carcinogenesis. 2020 Jul 25. Epub 2020 Jul 25. PMID: 32710739
Article Published Date : Jul 24, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Artesunate
Diseases : Gastrointestinal Cancer
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive, Wnt/β-catenin signaling pathway modulation
[+]

Curcumin exhibits anti-gastrointestinal cancer activity in rats.Sep 01, 2006

Pubmed Data : Cancer Sci. 2006 Sep;97(9):896-904. Epub 2006 Jun 29. PMID: 16805852
Article Published Date : Sep 01, 2006
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Gastric Cancer, Gastrointestinal Cancer
Pharmacological Actions : Antineoplastic Agents, Chemopreventive, Gastroprotective
[+]

Dietary curcumin inhibits forestomach, duodenal, and colon carcinogenesis in mice.Nov 15, 1994

Pubmed Data : Cancer Res. 1994 Nov 15;54(22):5841-7. PMID: 7954412
Article Published Date : Nov 15, 1994
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Benzo[a]pyrene-induced Toxicity , Colon Cancer, Gastric Cancer, Gastrointestinal Cancer
Pharmacological Actions : Chemopreventive
[+]

High-fat diet-induced dysbiosis mediates MCP-1/CCR2 axis-dependent M2 macrophage polarization and promotes intestinal adenoma-adenocarcinoma sequence.Jan 18, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2020 Jan 19. Epub 2020 Jan 19. PMID: 31957197
Article Published Date : Jan 18, 2020
Study Type : Animal Study
Additional Links
Diseases : Dysbiosis, Gastrointestinal Cancer, High Fat Diet
Additional Keywords : Risk Factors
[+]

Radioprotective effect of mistletoe extract on intestinal toxicity.Nov 06, 2022

Pubmed Data : Int J Radiat Biol. 2022 Nov 7:1-8. Epub 2022 Nov 7. PMID: 36318746
Article Published Date : Nov 06, 2022
Study Type : Animal Study
Additional Links
Substances : Mistletoe
Diseases : Gastrointestinal Cancer
Pharmacological Actions : Radioprotective
[+]

Sulforaphane and dibenzoylmethane alone as well as their combination are potent natural dietary compounds for chemoprevention of gastrointestinal cancers.Oct 15, 2007

Pubmed Data : Cancer Res. 2007 Oct 15;67(20):9937-44. PMID: 17942926
Article Published Date : Oct 15, 2007
Study Type : Animal Study
Additional Links
Substances : Dibenzoylmethane (DBM), Sulforaphane
Diseases : Adenomatous Polyposis Coli, Gastrointestinal Cancer
Pharmacological Actions : Anticarcinogenic Agents, Apoptotic, Chemopreventive
[+]

Tart cherry appears to have a chemopreventive property in intestinal and colon cancer. Dec 13, 2006

Pubmed Data : J Agric Food Chem. 2006 Dec 13 ;54(25):9322-8. PMID: 17147414
Article Published Date : Dec 13, 2006
Study Type : Animal Study
Additional Links
Substances : Anthocyanins, Tart Cherry
Diseases : Colon Cancer, Gastrointestinal Cancer
Pharmacological Actions : Antineoplastic Agents, Chemopreventive
Additional Keywords : Plant Extracts
[+]

Various plant phenols inhibit benzo[a]pyrene-induced nuclear a.berrations in mammalian intestinal cellsJan 01, 1985

Pubmed Data : Food Chem Toxicol. 1985 Jan;23(1):47-9. PMID: 4038681
Article Published Date : Jan 01, 1985
Study Type : Animal Study
Additional Links
Substances : Curcumin, Ellagic Acid, Quercetin
Diseases : Benzo[a]pyrene-induced Toxicity , Gastrointestinal Cancer
Pharmacological Actions : Chemopreventive
[+]

A review of allicin and digestive system cancers.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Oncol. 2021 ;11:650256. Epub 2021 Apr 27. PMID: 33987085
Article Published Date : Dec 31, 2020
Study Type : Review
Additional Links
Substances : Allicin
Diseases : Gastrointestinal Cancer
Pharmacological Actions : Chemopreventive
[+]

A review of curcumin against gastrointestinal cancer.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:990475. Epub 2022 Sep 2. PMID: 36120367
Article Published Date : Dec 31, 2021
Study Type : Review
Additional Links
Substances : Curcumin
Diseases : Gastrointestinal Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, Autophagy Up-regulation, Cell cycle arrest
[+]

Allicin in digestive system cancer: From biological effects to clinical treatment.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:903259. Epub 2022 Jun 13. PMID: 35770084
Article Published Date : Dec 31, 2021
Study Type : Review
Additional Links
Substances : Allicin
Diseases : Gastrointestinal Cancer
Pharmacological Actions : Angiogenesis Inhibitors, Anti-metastatic, Antiproliferative , Apoptotic
[+]

Anti-stem cell property of pterostilbene in gastrointestinal cancer cells.Dec 07, 2020

Pubmed Data : Int J Mol Sci. 2020 Dec 8 ;21(24). Epub 2020 Dec 8. PMID: 33302440
Article Published Date : Dec 07, 2020
Study Type : In Vitro Study
Additional Links
Substances : Pterostilbene
Diseases : Gastrointestinal Cancer
Pharmacological Actions : Antiproliferative
[+]

Antimetastatic effects of curcumin in oral and gastrointestinal cancers.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2021 ;12:668567. Epub 2021 Aug 11. PMID: 34456716
Article Published Date : Dec 31, 2020
Study Type : Review
Additional Links
Substances : Curcumin
Diseases : Gastrointestinal Cancer
Pharmacological Actions : Anti-metastatic
[+]

Antimicrobial, antioxidant and anticancer activities of Laurencia catarinensis, Laurencia majuscula and Padina pavonica extracts.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Saudi Pharm J. 2018 Jan ;26(1):44-52. Epub 2017 Nov 10. PMID: 29379332
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Red Marine Algae, Seaweed: Brown
Diseases : Aspergillosis, Breast Cancer, Candida Infection , Cervical Cancer, Gastrointestinal Cancer, Laryngeal Cancer, Liver Cancer, Lung Cancer
Pharmacological Actions : Antimicrobial, Antiproliferative
Additional Keywords : Plant Extracts
[+]

Applications of resveratrol in the treatment of gastrointestinal cancer.Jun 16, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2022 Jun 17 ;153:113274. Epub 2022 Jun 17. PMID: 35724505
Article Published Date : Jun 16, 2022
Study Type : Review
Additional Links
Substances : Resveratrol
Diseases : Gastrointestinal Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Chemosensitizer
[+]

Berberine induces combined cell death in gastrointestinal cell lines.Mar 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2023 Apr 1 ;24(7). Epub 2023 Apr 1. PMID: 37047563
Article Published Date : Mar 31, 2023
Study Type : In Vitro Study
Additional Links
Substances : Berberine
Diseases : Gastrointestinal Cancer
Pharmacological Actions : Apoptotic
[+]

Curcumin prevents chemically-induced inflammation in gastrointestinal lines associated with cancer promotion.Feb 01, 2009

Pubmed Data : J Invest Dermatol. 2009 Feb;129(2):468-75. Epub 2008 Aug 14. PMID: 10190560
Article Published Date : Feb 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Cancers: All, Gastrointestinal Cancer, Inflammation
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors
[+]

Effect of Shan Zha (Hawthorn or Crataegus) on gastrointestinal cancer.Sep 30, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Pathog Ther. 2023 Oct ;1(4):229-237. Epub 2023 Feb 7. PMID: 38327605
Article Published Date : Sep 30, 2023
Study Type : In Vitro Study
Additional Links
Substances : Hawthorn
Diseases : Gastrointestinal Cancer
Pharmacological Actions : Chemotherapeutic
[+]

Ginsenoside Rg3 attenuates tumor angiogenesis via inhibiting bioactivities of endothelial progenitor cells.Apr 30, 2012

Pubmed Data : Cancer Biol Ther. 2012 May ;13(7):504-15. Epub 2012 May 1. PMID: 22406998
Article Published Date : Apr 30, 2012
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Gastrointestinal Cancer, Lung Cancer, Melanoma
Pharmacological Actions : Angiogenesis Inhibitors, Antiproliferative
[+]

Ginsenosides: Allies of gastrointestinal tumor immunotherapy.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:922029. Epub 2022 Oct 31. PMID: 36386161
Article Published Date : Dec 31, 2021
Study Type : Review
Additional Links
Substances : Ginsenosides
Diseases : Gastrointestinal Cancer
Pharmacological Actions : Chemotherapeutic, Immunomodulatory
[+]

IGF-1 in rBGH milk is a potential risk factor for both breast and gastrointestinal cancers.Jan 01, 1996

Pubmed Data : Int J Health Serv. 1996;26(1):173-85. PMID: 8932606
Article Published Date : Jan 01, 1996
Study Type : Commentary
Additional Links
Diseases : Breast Cancer, Gastrointestinal Cancer
Problem Substances : IGF-1, Recombinant Bovine Growth Hormone (rBGH)
[+]

In this review, the evidences for the chemopreventive and chemotherapeutic potential of ginger extract and its active components using in vitro, animal models, and patients have been described.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Gastroenterol Res Pract. 2015 ;2015:142979. Epub 2015 Mar 8. PMID: 25838819
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Substances : 6-Shogaol, Ginger, Gingerol
Diseases : Cancers: All, Gastrointestinal Cancer
Pharmacological Actions : Anti-metastatic, Anticarcinogenic Agents, Apoptotic, Chemopreventive, Chemotherapeutic
Additional Keywords : Significant Treatment Outcome
[+]

In vitro and Pharmacoinformatics-based phytochemical screening for anticancer impacts of pistachio hull essential oil on AGS, PLC/PRF/5, and CACO2 cell lines.Nov 07, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Biol Rep. 2022 Nov 8. Epub 2022 Nov 8. PMID: 36348196
Article Published Date : Nov 07, 2022
Study Type : In Vitro Study
Additional Links
Substances : Pistachio nut
Diseases : Gastrointestinal Cancer
Pharmacological Actions : Chemotherapeutic, Wnt/β-catenin signaling pathway modulation
[+]

Neferine inhibits growth and migration of gastrointestinal stromal tumor cell line GIST-T1.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Jan ;109:1951-1959. Epub 2018 Nov 26. PMID: 30551450
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Lotus
Diseases : Gastrointestinal Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, MicroRNA modulator
[+]

Preventive and therapeutic roles of berberine in gastrointestinal cancers.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2019 ;2019:6831520. Epub 2019 Dec 28. PMID: 31950049
Article Published Date : Dec 31, 2018
Study Type : Review
Additional Links
Substances : Berberine
Diseases : Gastrointestinal Cancer
Pharmacological Actions : Chemopreventive, Chemotherapeutic
Additional Keywords : Tumor Microenvironment
[+]

Probiotics and their role in gastrointestinal cancers prevention and treatment; an overview.Dec 31, 2017

Pubmed Data : Gastroenterol Hepatol Bed Bench. 2018 ;11(4):284-295. PMID: 30425806
Article Published Date : Dec 31, 2017
Study Type : Review
Additional Links
Substances : Probiotics
Diseases : Gastrointestinal Cancer
Pharmacological Actions : Chemopreventive, Chemotherapeutic
[+]

Pterostilbene enhances sorafenib's anticancer effects on gastric adenocarcinoma.Oct 31, 2020

Pubmed Data : J Cell Mol Med. 2020 Nov ;24(21):12525-12536. Epub 2020 Oct 13. PMID: 33047871
Article Published Date : Oct 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Pterostilbene
Diseases : Gastrointestinal Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Autophagy Up-regulation
Additional Keywords : Chemothapeutic Synergy: Sorafenib
[+]

Radiotherapy may adversely effect the nutritional status of the patient.Jul 01, 1977

Pubmed Data : Cancer Res. 1977 Jul;37(7 Pt 2):2407-13. PMID: 861954
Article Published Date : Jul 01, 1977
Study Type : Commentary
Additional Links
Diseases : Gastrointestinal Cancer
Anti Therapeutic Actions : Radiotherapy
[+]

The role of phytonutrient kaempferol in the prevention of gastrointestinal cancers.Apr 26, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancers (Basel). 2024 Apr 27 ;16(9). Epub 2024 Apr 27. PMID: 38730663
Article Published Date : Apr 26, 2024
Study Type : Review
Additional Links
Substances : Kaempferol
Diseases : Gastrointestinal Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative
[+]

The studies to date offer strong evidence to support the use of DIM as an anticancer and therapeutic agent for gastrointestinal cancer.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2016 ;17(7). Epub 2016 Jul 19. PMID: 27447608
Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Diseases : Gastrointestinal Cancer
Pharmacological Actions : Chemopreventive
[+]

The therapeutic effects of berberine for gastrointestinal cancers.Mar 12, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asia Pac J Clin Oncol. 2023 Mar 13. Epub 2023 Mar 13. PMID: 36915942
Article Published Date : Mar 12, 2023
Study Type : Review
Additional Links
Substances : Berberine
Diseases : Gastrointestinal Cancer
Pharmacological Actions : Antiproliferative
[+]

Therapeutic potential of emodin for gastrointestinal cancers. Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Integr Cancer Ther. 2022 Jan-Dec;21:15347354211067469. PMID: 34984952
Article Published Date : Dec 31, 2021
Study Type : Review
Additional Links
Substances : Emodin
Diseases : Gastrointestinal Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Apoptotic

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