Diabetes: Cataract

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44 Substances Researched for Diabetes: Cataract
NameACCKFocus
Flavonoids35Locked
Bael 24Locked
Cannabidiol24Locked
Fenugreek34Locked
Lotus 24Locked
Puerarin24Locked
Curcumin23Locked
Icariin13Locked
Paeoniflorin23Locked
Plumbagin23Locked
Rose 23Locked
Amla Fruit12Locked
Anthocyanins12Locked
Astaxanthin12Locked
Blueberry12Locked
Broccoli Sprouts12Locked
Cannabis12Locked
Chlorella (Algae)12Locked
Cinnamaldehyde12Locked
Citric Acid 12Locked
Corn: Purple12Locked
Diosgenin12Locked
Diosmin 12Locked
EGCG (Epigallocatechin gallate)12Locked
Ginkgo biloba12Locked
Lime12Locked
Lychee12Locked
Naringenin 12Locked
Onion12Locked
Potato12Locked
Pterocarpus marsupium12Locked
Quercetin12Locked
Resveratrol12Locked
Rutin12Locked
Syringic Acid12Locked
Thymol12Locked
Zinc12Locked
Apigenin11Locked
Baicalein11Locked
Chrysin11Locked
Genistein11Locked
Goji11Locked
Cocoa10Locked
Vanadium10Locked
Related Topics

Diabetes: Cataract is a Sub of the following Topics

View the Evidence:
44 Abstracts with Diabetes: Cataract Research

[+]

Icariin interacts with IGFBP3 to alleviate diabetic cataract through PI3K/AKT signaling pathway.Jul 17, 2025

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : iScience. 2025 Jul 18 ;28(7):112796. Epub 2025 May 30. PMID: 40620905
Article Published Date : Jul 17, 2025
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Icariin
Diseases : Diabetes: Cataract
Pharmacological Actions : Anti-Apoptotic, Antioxidants
[+]

Resveratrol may have potential therapeutic applications for prevention of diabetes-induced visual dysfunction.Jul 01, 2010

Pubmed Data : Diabetes. 2010 Jul;59(7):1825-35. Epub 2010 Apr 27. PMID: 20424226
Article Published Date : Jul 01, 2010
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Diabetes: Cataract, Diabetes: Visual Dysfunction
Pharmacological Actions : Antioxidants, Apoptotic, Enzyme Inhibitors
Additional Keywords : Stilbenes
[+]

Aegle marmelos Correa leaf extract prevents secondary complications in streptozotocin-induced diabetic rats.May 31, 2013

Pubmed Data : J Pharm Pharmacol. 2013 Jun ;65(6):884-94. Epub 2013 Feb 26. PMID: 23647682
Article Published Date : May 31, 2013
Study Type : Animal Study
Additional Links
Substances : Bael
Diseases : Advanced Glycation End products (AGE), Diabetes: Cataract
Pharmacological Actions : Anti-Glycation Agents, Antioxidants, Hypoglycemic Agents, Renoprotective
Additional Keywords : Plant Extracts
[+]

Antidiabetic cataract effects of Ginkgo biloba extract, rutin and quercetin are mediated by the inhibition of oxidative stress and polyol pathway.Dec 27, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Biochim Pol. 2017 Dec 28. Epub 2017 Dec 28. PMID: 29281744
Article Published Date : Dec 27, 2017
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba, Quercetin, Rutin
Diseases : Advanced Glycation End products (AGE), Diabetes: Cataract
Pharmacological Actions : Anti-Glycation Agents, Antioxidants
[+]

Antioxidative effect of flavonoid naringenin in the lenses of type 1 diabetic rats.Nov 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2018 Dec ;108:974-984. Epub 2018 Sep 27. PMID: 30372909
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Naringenin
Diseases : Diabetes: Cataract, Diabetes: Oxidative Stress, Diabetes Mellitus: Type 1
Pharmacological Actions : Antioxidants
[+]

Blueberry anthocyanin extract significantly delayed the progression of diabetic cataracts.May 31, 2020

Pubmed Data : Curr Eye Res. 2020 Jun 1. Epub 2020 Jun 1. PMID: 32478572
Article Published Date : May 31, 2020
Study Type : Animal Study
Additional Links
Substances : Anthocyanins, Blueberry
Diseases : Diabetes: Cataract
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, NF-kappaB Inhibitor, Superoxide Dismutase Up-regulation
[+]

Broccoli sprout juice has a significant effect in preventing lens protein aggregation in diabetic rat model.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Ophthalmol. 2019 ;12(9):1380-1385. Epub 2019 Sep 18. PMID: 31544030
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Broccoli Sprouts
Diseases : Diabetes: Cataract
Pharmacological Actions : Antioxidants
[+]

Cannabidiol has a neuroprotective and blood-retinal-preserving effect in experimental diabetes. Jan 01, 2004

Pubmed Data : Int Urol Nephrol. 2004;36(4):591-8. PMID: 16400026
Article Published Date : Jan 01, 2004
Study Type : Animal Study
Additional Links
Substances : Cannabidiol
Diseases : Diabetes: Cataract, Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 2, Oxidative Stress
Pharmacological Actions : Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Vascular Endothelial Growth Factor A Inhibitor
[+]

Cannabidiol protects retinal neurons by preserving glutamine synthetase activity in diabetes.Jan 01, 2010

Pubmed Data : Mol Vis. 2010;16:1487-95. Epub 2010 Aug 4. PMID: 20806080
Article Published Date : Jan 01, 2010
Study Type : Animal Study
Additional Links
Substances : Cannabidiol, Cannabis
Diseases : Diabetes: Cataract
[+]

Chlorella has antioxidant and ant-catarct effects on rats with type 1 diabetes. Oct 01, 2003

Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2003 Oct;49(5):334-9. PMID: 14703308
Article Published Date : Oct 01, 2003
Study Type : Animal Study
Additional Links
Substances : Chlorella (Algae)
Diseases : Diabetes: Cataract, Diabetes Mellitus: Type 1
[+]

Cinnamaldehyde attenuates cataractogenesis via restoration of hypertension and oxidative stress.May 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharmacopuncture. 2016 Jun ;19(2):137-44. PMID: 27386147
Article Published Date : May 31, 2016
Study Type : Animal Study
Additional Links
Substances : Cinnamaldehyde
Diseases : Cataract, Diabetes: Cataract, High Fructose Diet, Hypertension, Oxidative Stress
Pharmacological Actions : Antihypertensive Agents, Antioxidants, Malondialdehyde Down-regulation
[+]

Citric acid ameliorates ketosis and protects against the development of diabetic complications in an animal model of type 1 diabetes.Feb 25, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biochem Biophys Res Commun. 2010 Feb 26 ;393(1):118-22. Epub 2010 Feb 1. PMID: 20117096
Article Published Date : Feb 25, 2010
Study Type : Animal Study
Additional Links
Substances : Citric Acid
Diseases : Diabetes: Cataract, Diabetes Mellitus: Type 1, Ketosis: Diabetic, Proteinuria
Pharmacological Actions : Anti-Glycation Agents
[+]

Citrus hystrix leaf extract attenuated diabetic-cataract in STZ-rats.Jun 14, 2020

Pubmed Data : J Food Biochem. 2020 Jun 15:e13258. Epub 2020 Jun 15. PMID: 32539198
Article Published Date : Jun 14, 2020
Study Type : Animal Study
Additional Links
Substances : Lime
Diseases : Diabetes: Cataract
Pharmacological Actions : Anti-Inflammatory Agents, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Diosgenin rich food can be recommended to diabetic subjects as dietary management to postpone the occurrence of sugar cataract.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Diabetes Res. 2017 ;2017:7309816. Epub 2017 Sep 5. PMID: 29038789
Article Published Date : Dec 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Diosgenin
Diseases : Diabetes: Cataract
Pharmacological Actions : Prophylactic Agents
[+]

Diosmin ameliorates the effects of oxidative stress in lenses of streptozotocin-induced type 1 diabetic rats.Sep 30, 2017

Pubmed Data : Pharmacol Rep. 2017 Oct ;69(5):995-1000. Epub 2017 Apr 15. PMID: 28846859
Article Published Date : Sep 30, 2017
Study Type : Animal Study
Additional Links
Substances : Diosmin
Diseases : Diabetes: Cataract, Diabetes: Oxidative Stress, Diabetes Mellitus: Type 1
Pharmacological Actions : Antioxidants, Superoxide Dismutase Up-regulation
Additional Keywords : Risk Reduction
[+]

Effect of astaxanthin on metabolic cataract in rats with type 1 diabetes mellitus.Jan 06, 2020

Pubmed Data : Exp Mol Pathol. 2020 Jan 7:104372. Epub 2020 Jan 7. PMID: 31923424
Article Published Date : Jan 06, 2020
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Diabetes: Cataract, Diabetes Mellitus: Type 1
Pharmacological Actions : Antioxidants
[+]

Effect of epigallocatechin gallate in green tea on preventing lens opacity and αB-crystallin aggregation.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Ophthalmol. 2023 ;16(3):342-347. Epub 2023 Mar 18. PMID: 36935798
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Diabetes: Cataract
[+]

Emblica (amla) tannoids are effective in delaying development of diabetic cataract in rats.Jul 24, 2007

Pubmed Data : Mol Vis. 2007 Jul 24;13:1291-7. PMID: 17679931
Article Published Date : Jul 24, 2007
Study Type : Animal Study
Additional Links
Substances : Amla Fruit
Diseases : Cataract, Diabetes: Cataract
[+]

Fruit pericarp extract of Litchi chinensis was found to delay the progression of diabetic cataractogenesis and retinopathy.Feb 28, 2017

Pubmed Data : Cutan Ocul Toxicol. 2017 Mar ;36(1):52-59. Epub 2016 May 10. PMID: 27160797
Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Substances : Lychee
Diseases : Advanced Glycation End products (AGE), Diabetes: Cataract, Retinopathy: Diabetic
Pharmacological Actions : Anti-Glycation Agents, Antioxidants, Catalase Up-Regulation, Superoxide Dismutase Up-regulation
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Inhibition of aldose reductase by Aegle marmelos and its protective role in diabetic cataract.Aug 25, 2013

Pubmed Data : J Ethnopharmacol. 2013 Aug 26 ;149(1):215-21. Epub 2013 Jul 1. PMID: 23827758
Article Published Date : Aug 25, 2013
Study Type : Animal Study
Additional Links
Substances : Bael
Diseases : Diabetes: Cataract
Pharmacological Actions : Aldose reductase inhibitor , Antioxidants, Hypoglycemic Agents
Additional Keywords : Plant Extracts
[+]

Lotus stamen has aldose reductase inhibitory which may have value in preventing diabetes-associated eye damage. Oct 01, 2006

Pubmed Data : Phytother Res. 2006 Oct;20(10):825-30. PMID: 16881021
Article Published Date : Oct 01, 2006
Study Type : Animal Study
Additional Links
Substances : Flavonoids, Lotus
Diseases : Diabetes: Cataract
Pharmacological Actions : Aldose reductase inhibitor
Additional Keywords : Plant Extracts
[+]

Nelumbo nucifera leaves have a therapeutic effect on rat lens aldose reductase, advanced glycation endproduct formation and oxidative stress. Dec 01, 2008

Pubmed Data : Food Chem Toxicol. 2008 Dec;46(12):3818-26. Epub 2008 Oct 10. PMID: 18952135
Article Published Date : Dec 01, 2008
Study Type : Animal Study
Additional Links
Substances : Lotus
Diseases : Diabetes: Cataract, Diabetes: Glycation/A1C
Pharmacological Actions : Aldose reductase inhibitor , Antioxidants
[+]

Peritoneal and peribulbar injection of puerarin have similar therapeutic effects in the treatment of rat diabetic cataract.Mar 31, 2011

Pubmed Data : Zhonghua Yan Ke Za Zhi. 2011 Apr ;47(4):320-6. PMID: 21612681
Article Published Date : Mar 31, 2011
Study Type : Animal Study
Additional Links
Substances : Puerarin
Diseases : Diabetes: Cataract
[+]

Plumbagin protects against cataract formation in STZ-induced diabetic cataract.Dec 03, 2025

Pubmed Data : Exp Eye Res. 2025 Dec 4:110792. Epub 2025 Dec 4. PMID: 41352650
Article Published Date : Dec 03, 2025
Study Type : Animal Study
Additional Links
Substances : Plumbagin
Diseases : Diabetes: Cataract
Pharmacological Actions : Antioxidants, Hypoglycemic Agents, Prophylactic Agents
[+]

Potato peel powder supplementation in diet was found to effectively attenuate diabetic alterations in rats.Mar 01, 2005

Pubmed Data : Clin Chim Acta. 2005 Mar;353(1-2):165-75. PMID: 15698604
Article Published Date : Mar 01, 2005
Study Type : Animal Study
Additional Links
Substances : Potato
Diseases : Diabetes: Cataract, Diabetes Mellitus: Type 1, Hyperglycemia, Oxidative Stress
Pharmacological Actions : Antioxidants
[+]

Pterocarpus marsupium and fenugreek seeds have anti-cataract activity in type 1 diabetic rats. Aug 01, 2004

Pubmed Data : J Ethnopharmacol. 2004 Aug;93(2-3):289-94. PMID: 15234767
Article Published Date : Aug 01, 2004
Study Type : Animal Study
Additional Links
Substances : Fenugreek, Pterocarpus marsupium
Diseases : Cataract, Diabetes: Cataract
Pharmacological Actions : Hypoglycemic Agents
Additional Keywords : Plant Extracts
[+]

Puerarin decreases lens epithelium cell apoptosis induced partly by peroxynitrite in diabetic rats.Dec 24, 2006

Pubmed Data : Sheng Li Xue Bao. 2006 Dec 25 ;58(6):584-92. PMID: 17173194
Article Published Date : Dec 24, 2006
Study Type : Animal Study
Additional Links
Substances : Puerarin
Diseases : Diabetes: Cataract
Pharmacological Actions : Anti-Apoptotic
[+]

Puerarin had hypoglycemic effects and that it prevented cataract development and progression in diabetic rats.Jun 02, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2019 Jun 3. Epub 2019 Jun 3. PMID: 31173182
Article Published Date : Jun 02, 2019
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Diabetes: Cataract
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Hypoglycemic Agents, Interleukin-1 beta downregulation, Nrf2 activation
[+]

Purple waxy corn has a preventive effect on experimental diabetic cataracts.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2014 ;2014:507435. Epub 2014 Jan 16. PMID: 24527449
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Corn: Purple
Diseases : Diabetes: Cataract, Oxidative Stress
Pharmacological Actions : Antioxidants
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Rose hydrosol exerts significant protective properties in diabetes mellitus.Nov 09, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 Nov 10 ;24(22). Epub 2019 Nov 10. PMID: 31717650
Article Published Date : Nov 09, 2019
Study Type : Animal Study
Additional Links
Substances : Rose
Diseases : Diabetes: Cataract, Diabetic Complications
Pharmacological Actions : Aldose reductase inhibitor
Additional Keywords : Plant Extracts
[+]

Syringic acid extracted from Herba dendrobii prevents diabetic cataract pathogenesis.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2012 ;2012:426537. Epub 2012 Dec 29. PMID: 23365598
Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Substances : Syringic Acid
Diseases : Diabetes: Cataract
[+]

Taxifolin shows anticataractogenesis and attenuates diabetic retinopathy.Dec 31, 2019

Pubmed Data : Endocr Metab Immune Disord Drug Targets. 2020 ;20(4):599-608. PMID: 31656158
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Diabetes: Cataract, Diabetic Retinopathy
Pharmacological Actions : Antioxidants
[+]

The present investigation evidenced a beneficial modulation of the progression of cataractogenesis by dietary fenugreek seeds and onion.May 31, 2018

Pubmed Data : Curr Eye Res. 2018 Jun 1. Epub 2018 Jun 1. PMID: 29856678
Article Published Date : May 31, 2018
Study Type : Animal Study
Additional Links
Substances : Fenugreek, Onion
Diseases : Diabetes: Cataract
Pharmacological Actions : Antioxidants
Additional Keywords : Antioxidants, Diabetes: Cataract, Fenugreek, Onion
[+]

Thymol may be a potential therapeutic approach in the prevention of diabetic complications.Sep 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharm Bioallied Sci. 2016 Oct-Dec;8(4):277-283. PMID: 28216950
Article Published Date : Sep 30, 2016
Study Type : Animal Study
Additional Links
Substances : Thymol
Diseases : Diabetes: Cataract, Diabetic Complications
Pharmacological Actions : Antioxidants
[+]

Tumeric and curcumin may prevent or delay the development of cataract. Jan 01, 2008

Pubmed Data : Nutr J. 2008;7:3. Epub 2008 Jan 21. PMID: 15914628
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Cataract, Diabetes: Cataract
[+]

Zinc supplementation ameliorates diabetic cataract.May 12, 2018

Pubmed Data : Biol Trace Elem Res. 2018 May 13. Epub 2018 May 13. PMID: 29756175
Article Published Date : May 12, 2018
Study Type : Animal Study
Additional Links
Substances : Zinc
Diseases : Diabetes: Cataract
Pharmacological Actions : Enzyme Inhibitors
[+]

Activation of Sirtuin1 by lyceum barbarum polysaccharides in protection against diabetic cataract.Oct 27, 2020

Pubmed Data : J Ethnopharmacol. 2020 Oct 28 ;261:113165. Epub 2020 Jul 27. PMID: 32730875
Article Published Date : Oct 27, 2020
Study Type : In Vitro Study
Additional Links
Substances : Goji
Diseases : Diabetes: Cataract
Pharmacological Actions : Anti-Apoptotic
[+]

Curcumin exhibits anti-cataract activity in the diabetic rat lens.Jan 01, 2005

Pubmed Data : Mol Vis. 2005;11:561-8. Epub 2005 Jul 26. PMID: 16088325
Article Published Date : Jan 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Cataract, Diabetes: Cataract
Pharmacological Actions : Antioxidants
[+]

Paeoniflorin inhibits epithelial mesenchymal transformation and oxidative damage of lens epithelial cells in diabetic cataract.Feb 28, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Bioengineered. 2022 Mar ;13(3):5903-5914. PMID: 35184653
Article Published Date : Feb 28, 2022
Study Type : In Vitro Study
Additional Links
Substances : Paeoniflorin
Diseases : Diabetes: Cataract
Pharmacological Actions : Antioxidants
[+]

The results concluded that plumbagin has promising anticataract activity.Sep 29, 2025

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharmacopuncture. 2025 Sep 30 ;28(3):191-200. PMID: 41018876
Article Published Date : Sep 29, 2025
Study Type : In Vitro Study
Additional Links
Substances : Plumbagin
Diseases : Diabetes: Cataract
Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Superoxide Dismutase Up-regulation
[+]

The results of the study clearly demonstrated the impressive anti-cataract activity of flavonoids.Jan 29, 2016

Pubmed Data : Arch Biochem Biophys. 2016 Jan 30 ;593:1-11. Epub 2016 Jan 30. PMID: 26829674
Article Published Date : Jan 29, 2016
Study Type : In Vitro Study
Additional Links
Substances : Apigenin, Baicalein, Chrysin, Flavonoids, Genistein
Diseases : Diabetes: Cataract
[+]

These findings provide theoretic basis and experimental evidence for the application of Rosa laevigata in the treatment of diabetic cataract.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Clin Exp Med. 2015 ;8(9):15759-65. Epub 2015 Sep 15. PMID: 26629073
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Rose
Diseases : Diabetes: Cataract
Pharmacological Actions : Antioxidants, Heme oxygenase-1 inducer, Nrf2 activation
[+]

A low dose vanadium compound in combination with Trignolla foenum (fenugreek) is effective in preventing diabetes-induced adverse changes in the lenses of diabetic mice. Mar 01, 2005

Pubmed Data : J Biosci. 2005 Mar;30(2):221-30. PMID: 15886458
Article Published Date : Mar 01, 2005
Additional Links
Substances : Fenugreek, Vanadium
Diseases : Diabetes: Cataract
[+]

Cocao proanthocyanidins inhibit diabetes-induced cataract formation. Oct 01, 2010

Pubmed Data : J Pharmacol Exp Ther. 2010 Oct;335(1):149-54. Epub 2010 Jul 7. PMID: 14709774
Article Published Date : Oct 01, 2010
Additional Links
Substances : Cocoa
Diseases : Cataract, Diabetes: Cataract

Copyright: rob3000 / 123RF Stock Photo

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