Chemotherapy-Induced Toxicity: Peripheral Neuropathy

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33 Substances Researched for Chemotherapy-Induced Toxicity: Peripheral Neuropathy
NameACCKFocus
Acetyl-l-carnitine431Locked
Alpha-Lipoic Acid322Locked
Cystine212Locked
Bromelain110Locked
Crocin110Locked
Lemon Balm110Locked
Vitamin D110Locked
Beta-Caryophyllene24Locked
Cannabigerol 24Locked
Cannabinoids 24Locked
Palmitoylethanolamide 24Locked
Pterostilbene24Locked
Theanine24Locked
Thymoquinone24Locked
Ginkgo biloba13Locked
Paeoniflorin23Locked
Apigenin12Locked
Astragaloside12Locked
Bee Venom12Locked
Caffeic acid phenethyl ester12Locked
Cannabidiol12Locked
Chlorogenic Acid12Locked
Citrus naringin12Locked
Curcumin12Locked
Gastrodin12Locked
Hesperidin12Locked
Honokiol12Locked
Lycopene12Locked
Piceatannol 12Locked
Syrian rue12Locked
Betulinic acid11Locked
Coenzyme Q1011Locked
Formononetin11Locked
1 Problem Substances Researched for Chemotherapy-Induced Toxicity: Peripheral Neuropathy
NameACCKFocus
Paclitaxel110Locked
10 Therapeutic Actions Researched for Chemotherapy-Induced Toxicity: Peripheral Neuropathy
NameACCKFocus
Acupuncture571Locked
Electroacupuncture545Locked
Cryotherapy541Locked
Photobiomodulation220Locked
Exercise110Locked
Massage/Therapeutic Touch110Locked
Reflexology 110Locked
Ultrasound therapy110Locked
Whole-Body Vibration 110Locked
Yoga110Locked

View the Evidence:
62 Abstracts with Chemotherapy-Induced Toxicity: Peripheral Neuropathy Research

[+]

The effectiveness and safety of acupuncture/electroacupuncture for chemotherapy-induced peripheral neuropathy.Jun 11, 2022

Pubmed Data : Acupunct Med. 2022 Jun 12:9645284221076512. Epub 2022 Jun 12. PMID: 35695033
Article Published Date : Jun 11, 2022
Study Type : Meta Analysis, Review
Additional Links
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Therapeutic Actions : Acupuncture, Electroacupuncture
Pharmacological Actions : Chemoprotective Agents
[+]

The efficacy of acupuncture in the treatment of chemotherapy-induced peripheral neuropathy.Sep 14, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Altern Ther Health Med. 2023 Sep 15. Epub 2023 Sep 15. PMID: 37708563
Article Published Date : Sep 14, 2023
Study Type : Meta Analysis
Additional Links
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Therapeutic Actions : Acupuncture
Pharmacological Actions : Chemoprotective Agents
[+]

Crocin considerably seems to be effective for relieving symptoms of CIPN in cancer patients receiving chemotherapy agents.Aug 10, 2021

Pubmed Data : J Ethnopharmacol. 2021 Aug 11 ;281:114511. Epub 2021 Aug 11. PMID: 34390797
Article Published Date : Aug 10, 2021
Study Type : Human Study
Additional Links
Substances : Crocin
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents
[+]

Acetyl-l-carnitine has a neuroprotective effect against chemotherapy-induced allodynia. May 01, 2005

Pubmed Data : In Vivo. 2005 May-Jun;19(3):631-7. PMID: 15875786
Article Published Date : May 01, 2005
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Allodynia, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Neuroprotective Agents
[+]

Acetyl-L-carnitine prevents and reduces paclitaxel-induced painful peripheral neuropathy.Apr 24, 2006

Pubmed Data : Neurosci Lett. 2006 Apr 24;397(3):219-23. Epub 2006 Jan 6. PMID: 16406309
Article Published Date : Apr 24, 2006
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy, Neuropathic Pain
[+]

Acupuncture and reflexology for chemotherapy-induced peripheral neuropathy in breast cancer.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Integr Cancer Ther. 2017 09 ;16(3):258-262. Epub 2017 Feb 2. PMID: 28150504
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Therapeutic Actions : Acupuncture, Massage/Therapeutic Touch, Reflexology
[+]

Acupuncture improves chemotherapy-induced neuropathy.Jun 25, 2022

Pubmed Data : Phytomedicine. 2022 Jun 26 ;104:154294. Epub 2022 Jun 26. PMID: 35785559
Article Published Date : Jun 25, 2022
Study Type : Human Study
Additional Links
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Therapeutic Actions : Acupuncture
Pharmacological Actions : Chemoprotective Agents
[+]

Alpha lipoic acid prevents mitochondrial damage and neurotoxicity in experimental chemotherapy neuropathy.Dec 01, 2008

Pubmed Data : Exp Neurol. 2008 Dec;214(2):276-84. Epub 2008 Sep 9. PMID: 18809400
Article Published Date : Dec 01, 2008
Study Type : Human Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Neuroprotective Agents
[+]

Beneficial effects of cryotherapy on chemotherapy-induced peripheral neuropathy.Dec 31, 2018

Pubmed Data : Nihon Yakurigaku Zasshi. 2019 ;154(5):245-248. PMID: 31735752
Article Published Date : Dec 31, 2018
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Therapeutic Actions : Cryotherapy
Pharmacological Actions : Chemoprotective Agents
Additional Keywords : Significant Treatment Outcome
[+]

Cryotherapy for the prevention of weekly paclitaxel-induced peripheral adverse events in breast cancer patients.Feb 07, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Support Care Cancer. 2020 Feb 8. Epub 2020 Feb 8. PMID: 32036471
Article Published Date : Feb 07, 2020
Study Type : Human Study
Additional Links
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Therapeutic Actions : Cryotherapy
Pharmacological Actions : Chemoprotective Agents
[+]

Cryotherapy helps to prevent paclitaxel induced peripheral neuropathy.Nov 30, 2019

Pubmed Data : Breast. 2019 Dec ;48:89-97. Epub 2019 Sep 19. PMID: 31590108
Article Published Date : Nov 30, 2019
Study Type : Human Study
Additional Links
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Therapeutic Actions : Cryotherapy
Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents
Additional Keywords : Risk Reduction
Problem Substances : Paclitaxel
[+]

Effect of cryotherapy on dose of adjuvant paclitaxel in early-stage breast cancer.Dec 10, 2019

Pubmed Data : Support Care Cancer. 2019 Dec 11. Epub 2019 Dec 11. PMID: 31828491
Article Published Date : Dec 10, 2019
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Therapeutic Actions : Cryotherapy
Pharmacological Actions : Chemoprotective Agents
[+]

Effect of Melissa officinalis on chemotherapy-induced peripheral neuropathy in cancer patients.Mar 31, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Hematol Oncol Stem Cell Res. 2024 Apr 1 ;18(2):165-173. PMID: 38868804
Article Published Date : Mar 31, 2024
Study Type : Human Study
Additional Links
Substances : Lemon Balm
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents
[+]

Efficacy and safety of electroacupuncture for oxaliplatin-induced peripheral neuropathy in colorectal cancer patients.Nov 02, 2022

Pubmed Data : Acupunct Med. 2022 Nov 3:9645284221125421. Epub 2022 Nov 3. PMID: 36325677
Article Published Date : Nov 02, 2022
Study Type : Human Study
Additional Links
Diseases : Chemotherapy-Induced Toxicity: Oxaliplatin, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents
[+]

Efficacy of exercise rehabilitation program in relieving oxaliplatin induced peripheral neurotoxicity.Feb 28, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Cancer Prev. 2021 Mar 1 ;22(3):705-709. Epub 2021 Mar 1. PMID: 33773532
Article Published Date : Feb 28, 2021
Study Type : Human Study
Additional Links
Diseases : Chemotherapy-Induced Toxicity: Oxaliplatin, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Therapeutic Actions : Exercise
Pharmacological Actions : Chemoprotective Agents
[+]

Electroacupuncture is effective in treating paclitaxel-induced chemotherapy-induced peripheral neuropathy.Oct 11, 2024

Pubmed Data : Zhongguo Zhen Jiu. 2024 Oct 12 ;44(10):1139-45. PMID: 39401811
Article Published Date : Oct 11, 2024
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents
[+]

OPERA was able to improve CIPN symptoms in a prospective series of patients treated with neurotoxic chemotherapy.Feb 28, 2017

Pubmed Data : Med Oncol. 2017 Mar ;34(3):46. Epub 2017 Feb 15. PMID: 28205185
Article Published Date : Feb 28, 2017
Study Type : Human Study
Additional Links
Substances : Alpha-Lipoic Acid, Bromelain
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Chemoprotective Agents
[+]

Photobiomodulation may offer clinically meaningful symptom benefit in cancer survivors with established chemotherapy-induced peripheral neuropathy.Dec 16, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Support Care Cancer. 2022 Dec 17 ;31(1):52. Epub 2022 Dec 17. PMID: 36526802
Article Published Date : Dec 16, 2022
Study Type : Human Study
Additional Links
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Neuroprotective Agents
[+]

Prophylactic acetyl-L-carnitine treatment against paclitaxel-evoked pain may be related to a protective effect on C-fiber mitochondria.Mar 01, 2008

Pubmed Data : Exp Neurol. 2008 Mar;210(1):229-37. Epub 2007 Nov 17. PMID: 18078936
Article Published Date : Mar 01, 2008
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy, Neuropathic Pain
Additional Keywords : Drug: Paclitaxel
[+]

Protective effect of the oral administration of cystine and theanine on oxaliplatin-induced peripheral neuropathy.Jun 26, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Clin Oncol. 2020 Jun 27. Epub 2020 Jun 27. PMID: 32594273
Article Published Date : Jun 26, 2020
Study Type : Human Study
Additional Links
Substances : Cystine
Diseases : Chemotherapy-Induced Toxicity: Oxaliplatin, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents
[+]

The effect of photobiomodulation on chemotherapy-induced peripheral neuropathy.Dec 31, 2016

Pubmed Data : Gynecol Oncol. 2017 Jan ;144(1):159-166. Epub 2016 Nov 22. PMID: 27887804
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Diseases : Cancers: All, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents
[+]

Ultrasound acupuncture for oxaliplatin-induced peripheral neuropathy in patients with colorectal cancer.Mar 10, 2020

Pubmed Data : PM R. 2020 Mar 11. Epub 2020 Mar 11. PMID: 32168417
Article Published Date : Mar 10, 2020
Study Type : Human Study
Additional Links
Diseases : Chemotherapy-Induced Toxicity: Oxaliplatin, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Therapeutic Actions : Acupuncture, Ultrasound therapy
Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents
[+]

Vitamin D deficiency increases severity of paclitaxel-induced peripheral neuropathy.Mar 31, 2020

Pubmed Data : Breast Cancer Res Treat. 2020 Apr ;180(3):707-714. Epub 2020 Mar 12. PMID: 32166478
Article Published Date : Mar 31, 2020
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy, Vitamin D Deficiency
Pharmacological Actions : Chemoprotective Agents
[+]

Whole-body vibration may improve physical fitness and coordination in patients suffering from chemotherapy-induced polyneuropathy.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Hematol Oncol. 2017 ;6:5. Epub 2017 Feb 7. PMID: 28194306
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Therapeutic Actions : Whole-Body Vibration
[+]

Yoga for chemotherapy-induced peripheral neuropathy and fall risk.Nov 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : JNCI Cancer Spectr. 2020 Dec ;4(6):pkaa048. Epub 2020 Jun 4. PMID: 33225208
Article Published Date : Nov 30, 2020
Study Type : Human Study
Additional Links
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Therapeutic Actions : Yoga
Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents
[+]

CB1 as a novel target for Ginkgo biloba's terpene trilactone for controlling chemotherapy-induced peripheral neuropathy.Aug 30, 2022

Pubmed Data : J Mol Model. 2022 Aug 31 ;28(9):283. Epub 2022 Aug 31. PMID: 36044079
Article Published Date : Aug 30, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Ginkgo biloba
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Analgesic effect of melittin on oxaliplatin-induced peripheral neuropathy in rats.Jan 07, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxins (Basel). 2019 07 8 ;11(7). Epub 2019 Jul 8. PMID: 31288453
Article Published Date : Jan 07, 2019
Study Type : Animal Study
Additional Links
Substances : Bee Venom
Diseases : Chemotherapy-Induced Toxicity: Oxaliplatin, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Chemoprotective Agents
[+]

Apigenin alleviates allodynia and hyperalgesia in a mouse model of chemotherapy-induced peripheral neuropathy.May 07, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Integr Neurosci. 2023 May 8 ;22(3):64. PMID: 37258427
Article Published Date : May 07, 2023
Study Type : Animal Study
Additional Links
Substances : Apigenin
Diseases : Allodynia, Chemotherapy-Induced Toxicity: Peripheral Neuropathy, Hyperalgesia
Pharmacological Actions : Anti-Inflammatory Agents, Chemoprotective Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Astragaloside IV alleviates Schwann cell injury in diabetic peripheral neuropathy by regulating microRNA-155-mediated autophagy.Sep 15, 2021

Pubmed Data : Phytomedicine. 2021 Sep 16 ;92:153749. Epub 2021 Sep 16. PMID: 34601220
Article Published Date : Sep 15, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Astragaloside
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Hypoglycemic Agents, Neuroprotective Agents
[+]

Beta-caryophyllene inhibits oxaliplatin-induced peripheral neuropathy.Oct 21, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2023 Oct 22 ;12(10). Epub 2023 Oct 22. PMID: 37891972
Article Published Date : Oct 21, 2023
Study Type : Animal Study
Additional Links
Substances : Beta-Caryophyllene
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Chemoprotective Agents
[+]

Caffeic acid phenethyl ester attenuates paclitaxel-induced peripheral neuropathyAug 28, 2022

Pubmed Data : Curr Neurovasc Res. 2022 Aug 29. Epub 2022 Aug 29. PMID: 36043777
Article Published Date : Aug 28, 2022
Study Type : Animal Study
Additional Links
Substances : Caffeic acid phenethyl ester
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents
[+]

Cannabigerol (CBG) attenuates mechanical hypersensitivity elicited by chemotherapy-induced peripheral neuropathy.Jan 09, 2022

Pubmed Data : Eur J Pain. 2022 10 ;26(9):1950-1966. Epub 2022 Aug 4. PMID: 35899583
Article Published Date : Jan 09, 2022
Study Type : Animal Study
Additional Links
Substances : Cannabigerol , Cannabinoids
Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents
[+]

Chlorogenic acid co-administration alleviates cisplatin-induced peripheral neuropathy.Nov 22, 2023

Pubmed Data : Fundam Clin Pharmacol. 2023 Nov 23. Epub 2023 Nov 23. PMID: 37996998
Article Published Date : Nov 22, 2023
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Chemoprotective Agents
[+]

Cystine and Theanine may be beneficial for preventing oxaliplatin-induced peripheral neuropathy.Jul 28, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2020 Jul 29 ;10(1):12665. Epub 2020 Jul 29. PMID: 32728157
Article Published Date : Jul 28, 2020
Study Type : Animal Study
Additional Links
Substances : Cystine, Theanine
Diseases : Chemotherapy-Induced Toxicity: Oxaliplatin, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents
[+]

Electroacupuncture alleviates paclitaxel-induced peripheral neuropathic pain.Nov 24, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Nov 25 ;20(23). Epub 2019 Nov 25. PMID: 31775332
Article Published Date : Nov 24, 2019
Study Type : Animal Study
Additional Links
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Analgesics, Chemoprotective Agents
[+]

Formulated curcumin prevents paclitaxel-induced peripheral neuropathy.Jun 16, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceutics. 2022 Jun 17 ;14(6). Epub 2022 Jun 17. PMID: 35745868
Article Published Date : Jun 16, 2022
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Anti-Inflammatory Agents, Chemoprotective Agents, Neuroprotective Agents
[+]

Harmaline demonstrates significant potential in mitigating vincristine-induced peripheral neuropathy.Sep 25, 2024

Pubmed Data : Neurosci Lett. 2024 Sep 26 ;842:138003. Epub 2024 Sep 26. PMID: 39341332
Article Published Date : Sep 25, 2024
Study Type : Animal Study
Additional Links
Substances : Syrian rue
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Antioxidants, Chemoprotective Agents, Nrf2 activation
[+]

Honokiol attenuates high glucose-induced peripheral neuropathy.Aug 13, 2023

Pubmed Data : Phytother Res. 2023 Aug 14. Epub 2023 Aug 14. PMID: 37580045
Article Published Date : Aug 13, 2023
Study Type : Animal Study
Additional Links
Substances : Honokiol
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Gene Expression Regulation
[+]

Lycopene protects against central and peripheral neuropathy by inhibiting oxaliplatin-induced ATF-6 pathway, apoptosis, inflammation and oxidative stress.Jun 12, 2020

Pubmed Data : Neurotoxicology. 2020 Jun 13 ;80:29-40. Epub 2020 Jun 13. PMID: 32544411
Article Published Date : Jun 12, 2020
Study Type : Animal Study
Additional Links
Substances : Lycopene
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Chemoprotective Agents
[+]

Oral cannabidiol for prevention of acute and transient chemotherapy-induced peripheral neuropathy.Aug 05, 2022

Pubmed Data : Support Care Cancer. 2022 Aug 6. Epub 2022 Aug 6. PMID: 35933415
Article Published Date : Aug 05, 2022
Study Type : Animal Study
Additional Links
Substances : Cannabidiol
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents
[+]

Paclitaxel-associated mechanical sensitivity and neuroinflammation are sex-, time-, and site-specific and prevented through cannabigerol administration.Apr 11, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2024 Apr 12 ;25(8). Epub 2024 Apr 12. PMID: 38673862
Article Published Date : Apr 11, 2024
Study Type : Animal Study
Additional Links
Substances : Cannabigerol , Cannabinoids
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy, Hyperalgesia, Inflammation
Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents
[+]

Paeoniflorin ameliorates oxaliplatin-induced peripheral neuropathy.May 14, 2024

Pubmed Data : Eur J Pharmacol. 2024 May 15 ;971:176516. Epub 2024 Mar 19. PMID: 38513881
Article Published Date : May 14, 2024
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Chemotherapy-Induced Toxicity: Oxaliplatin, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Neuroprotective Agents
[+]

Palmitoylethanolamide possesses potential to treat peripheral neuropathy in cancer patients undergoing chemotherapy.Oct 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharmacol Exp Ther. 2016 Nov ;359(2):310-318. Epub 2016 Sep 8. PMID: 27608657
Article Published Date : Oct 31, 2016
Study Type : Animal Study
Additional Links
Substances : Palmitoylethanolamide
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy, Hyperalgesia
Pharmacological Actions : Chemoprotective Agents
[+]

Piceatannol ameliorates behavioural, biochemical and histological aspects in cisplatin-induced peripheral neuropathy.Aug 12, 2021

Pubmed Data : Basic Clin Pharmacol Toxicol. 2021 Aug 13. Epub 2021 Aug 13. PMID: 34390194
Article Published Date : Aug 12, 2021
Study Type : Animal Study
Additional Links
Substances : Piceatannol
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents
[+]

Protective effect of alpha-lipoic acid and epalrestat on oxaliplatin-induced peripheral neuropathy.Mar 31, 2024

Pubmed Data : Muscle Nerve. 2024 Apr ;69(4):498-503. Epub 2024 Jan 31. PMID: 38294129
Article Published Date : Mar 31, 2024
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents
[+]

Protective effect of gastrodin on peripheral neuropathy induced by anti-tumor treatment.Dec 16, 2018

Pubmed Data : Drug Chem Toxicol. 2018 Dec 17:1-8. Epub 2018 Dec 17. PMID: 30554535
Article Published Date : Dec 16, 2018
Study Type : Animal Study
Additional Links
Substances : Gastrodin
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Anti-Inflammatory Agents, Chemoprotective Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Protective effect of naringin against oxaliplatin-induced peripheral neuropathy.Jun 06, 2022

Pubmed Data : J Biochem Mol Toxicol. 2022 Jun 7:e23121. Epub 2022 Jun 7. PMID: 35670529
Article Published Date : Jun 06, 2022
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Chemotherapy-Induced Toxicity: Oxaliplatin, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Chemoprotective Agents
[+]

Pterostilbene improves CFA-induced arthritis and peripheral neuropathy.Sep 21, 2022

Pubmed Data : Inflammopharmacology. 2022 Sep 22. Epub 2022 Sep 22. PMID: 36138303
Article Published Date : Sep 21, 2022
Study Type : Animal Study
Additional Links
Substances : Pterostilbene
Diseases : Arthritis, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

The ameliorative effect of thymoquinone on vincristine-induced peripheral neuropathy.Dec 28, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Life (Basel). 2022 Dec 29 ;13(1). Epub 2022 Dec 29. PMID: 36676049
Article Published Date : Dec 28, 2022
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Chemoprotective Agents, Neuroprotective Agents
[+]

The current study revealed the pivotal role of the RVM astrocytes in mediating the analgesic effects of EA on chemotherapy-induced peripheral neuropathic pain.Oct 14, 2024

Pubmed Data : Pain. 2024 Oct 15. Epub 2024 Oct 15. PMID: 39432736
Article Published Date : Oct 14, 2024
Study Type : Animal Study
Additional Links
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents
[+]

The neuroprotective effect of pterostilbene on oxaliplatin-induced peripheral neuropathy.Jan 03, 2023

Pubmed Data : Life Sci. 2023 Jan 4:121364. Epub 2023 Jan 4. PMID: 36610639
Article Published Date : Jan 03, 2023
Study Type : Animal Study
Additional Links
Substances : Pterostilbene
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Chemoprotective Agents, Cyclooxygenase 2 Inhibitors, Neuroprotective Agents, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

The protective effects of hesperidin against paclitaxel-induced peripheral neuropathy in rats.Oct 31, 2021

Pubmed Data : Life Sci. 2021 Nov 1 ;287:120104. Epub 2021 Nov 1. PMID: 34743946
Article Published Date : Oct 31, 2021
Study Type : Animal Study
Additional Links
Substances : Hesperidin
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Anti-Apoptotic, Chemoprotective Agents
[+]

These findings suggest that ultramicronized-palmitoylethanolamide is a promising adjunct in CIPN and associated mood disorders.Aug 19, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomolecules. 2022 Aug 20 ;12(8). Epub 2022 Aug 20. PMID: 36009049
Article Published Date : Aug 19, 2022
Study Type : Animal Study
Additional Links
Substances : Palmitoylethanolamide
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Anti-Anxiety Agents, Anti-Inflammatory Agents, Antidepressive Agents, Chemoprotective Agents, Neuroprotective Agents
[+]

Through its powerful antioxidative properties, L-theanine ameliorates vincristine-induced neuropathy.Mar 24, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2023 Mar 25 ;12(4). Epub 2023 Mar 25. PMID: 37107178
Article Published Date : Mar 24, 2023
Study Type : Animal Study
Additional Links
Substances : Theanine
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Thymoquinone alleviates paclitaxel-induced peripheral neuropathy.Oct 17, 2023

Pubmed Data : ACS Chem Neurosci. 2023 Oct 18 ;14(20):3804-3817. Epub 2023 Oct 9. PMID: 37813830
Article Published Date : Oct 17, 2023
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Anti-Inflammatory Agents, Chemoprotective Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

β-caryophyllene has antiallodynic effects on paclitaxel-induced peripheral neuropathy in mice.Sep 30, 2017

Pubmed Data : Neuropharmacology. 2017 Oct ;125:207-219. Epub 2017 Jul 18. PMID: 28729222
Article Published Date : Sep 30, 2017
Study Type : Animal Study
Additional Links
Substances : Beta-Caryophyllene
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Chemoprotective Agents
[+]

A Synthesis of cryotherapy interventions to reduce peripheral neuropathy and nail changes From taxane-based chemotherapy.Sep 30, 2019

Pubmed Data : Clin J Oncol Nurs. 2019 Oct 1 ;23(5):522-528. PMID: 31538978
Article Published Date : Sep 30, 2019
Study Type : Review
Additional Links
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Therapeutic Actions : Cryotherapy
Pharmacological Actions : Chemoprotective Agents, Neuroprotective Agents
[+]

Acetyl-l-carnitine has therapeutic activity in treating chemotherapy-induced peripheral neuropathy. Jan 01, 2007

Pubmed Data : CNS Drugs. 2007;21 Suppl 1:39-43; discussion 45-6. PMID: 17696592
Article Published Date : Jan 01, 2007
Study Type : Review
Additional Links
Substances : Acetyl-l-carnitine
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy, Peripheral Neuropathies
[+]

Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury-associated peripheral sensory neuropathyDec 31, 2018

Pubmed Data : Pain. 2019 Jan ;160(1):117-135. PMID: 30169422
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Betulinic acid
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel, Chemotherapy-Induced Toxicity: Peripheral Neuropathy, HIV Infections
Pharmacological Actions : Neuroprotective Agents
[+]

Formononetin ameliorates oxaliplatin-induced peripheral neuropathy.Aug 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Redox Biol. 2020 Sep ;36:101677. Epub 2020 Aug 6. PMID: 32823168
Article Published Date : Aug 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Formononetin
Diseases : Chemotherapy-Induced Toxicity: Oxaliplatin, Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Chemoprotective Agents
[+]

Paeoniflorin ameliorates BiPN by reducing IL6 levels and regulating PARKIN-mediated mitochondrial autophagy.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Des Devel Ther. 2022 ;16:2241-2259. Epub 2022 Jul 13. PMID: 35860525
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Paeoniflorin
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy, Multiple Myeloma
Pharmacological Actions : Anti-Inflammatory Agents, Chemoprotective Agents, Interleukin-6 Downregulation
[+]

Possible protective effects of CO Q10 against vincristine-induced peripheral neuropathy.Dec 22, 2021

Pubmed Data : J Biochem Mol Toxicol. 2021 Dec 23:e22976. Epub 2021 Dec 23. PMID: 34939713
Article Published Date : Dec 22, 2021
Study Type : In Vitro Study
Additional Links
Substances : Coenzyme Q10
Diseases : Chemotherapy-Induced Toxicity: Peripheral Neuropathy
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

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