Bone Fractures

Name	AC	CK
Vitamin K2	8	73
Vitamin D	9	58
Vitamin K	4	41
Vitamin A	1	20
beta-Carotene	1	20
Vitamin C	7	19
Garden Cress (Lepidium sativum)	2	12
Protein Supplement	2	12
Vitamin K2: Menaquinone-7	3	12
Magnesium	2	11
Vitamin K2: (MK-4)	2	11
Black Tea	1	10
DHEA (Dehydroepiandrosterone)	1	10
Flavonoids	1	10
Lysine	1	10
Melatonin	1	10
Proline	1	10
Soy	1	10
Strontium	1	10
Testosterone	1	10
Zinc	1	10
Cannabidiol	2	4
Red Sage	2	4
Royal Jelly	2	4
Tanshinone IIA	2	4
Almond	1	2
Amino Acids	1	2
Amygdalin	1	2
Astaxanthin	1	2
Bee Propolis	1	2
Caffeic acid phenethyl ester	1	2
Cannabigerol	1	2
Chaste Tree (Chasteberry)	1	2
Citrus naringin	1	2
Curcumin	1	2
Echinacea	1	2
Equol	1	2
Fucoidan	1	2
Genistein	1	2
Guduchi	1	2
Kaempferol	1	2
Lactoferrin	1	2
Mangiferin	1	2
Plumbum metallicum	1	2
Puerarin	1	2
Quercetin	1	2
Red Marine Algae	1	2
Turmeric	1	2
Velvet antler	1	2
phytoestrogens	1	2
Egg	1	1
Ginsenosides	1	1
Natto	1	1
Panax Notoginseng	1	1
Vitamin B6	1	1

Name	AC	CK
Bisphosphonates	3	21
Statin Drugs	2	20
Proton-Pump Inhibitors	3	12
Arimidex	1	10
Aromatase Inhibitor Drugs	1	10
Diuretic Drugs	1	10
Diuretic: Loop	1	10
Fluoride	1	10
Levothyroxine	1	10
Rosiglitazone (trade name Avandia)	1	10
Sodium Fluoride	1	10
Sugar Sweetened Beverages	1	10
13-cis-retinoic acid	1	2
Fluoroquinolone Antibiotic	1	2
Retinyl Acetate	1	2
Alendronate (trade name Fosamax)	1	1
Cow Milk	1	1
Etidronate	1	1

Name	AC	CK
Tai Chi	3	40
Whole-Body Vibration	2	30
Photobiomodulation	7	29
Dancing	1	10
Hypnosis	1	10
Pulsed EMF field (PEMF)	1	10
Ultrasound therapy	1	10
Yoga	1	10
Infrared Light	2	4
Hyperbaric Treatment	2	3
Acupuncture	1	2
Homeopathic Treatment	1	2
Magnet Therapy	1	2

Name	AC	CK	Focus
Western Diet	1	2

[+]

High-dose vitamin K supplementation reduces fracture incidence in postmenopausal women.Apr 01, 2009

Click here to read the entire abstract

Pubmed Data : Nutr Res. 2009 Apr;29(4):221-8. PMID: 19410972

Article Published Date : Apr 01, 2009

Study Type : Meta Analysis

Additional Links

Substances : Vitamin K, Vitamin K2

Diseases : Bone Fractures, Osteoporosis, Postmenopausal Disorders

[+]

Tai chi is effective in improving balance of older adults and in the absence of other interventions, reduces falls in the nonfrail elderly.Jan 01, 2011

Click here to read the entire abstract

Pubmed Data : Altern Ther Health Med. 2011 Jan-Feb;17(1):40-8. PMID: 21614943

Article Published Date : Jan 01, 2011

Study Type : Meta Analysis

Additional Links

Diseases : Bone Fractures, Elderly: Age Specific Diseases, Osteoporosis

Therapeutic Actions : Tai Chi

Additional Keywords : Risk Reduction

[+]

This meta-analysis suggests that blood retinol level is a double-edged sword for risk of hip fracture.Aug 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Bone Miner Res. 2014 Sep ;29(9):2032-9. PMID: 24700407

Article Published Date : Aug 31, 2014

Study Type : Meta Analysis

Additional Links

Substances : beta-Carotene, Vitamin A

Diseases : Bone Fractures

Additional Keywords : Risk Factors

[+]

This meta-analysis suggests that whole-body vibration may prevent fractures by reducing falls.Dec 28, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMJ Open. 2017 Dec 29 ;7(12):e018342. Epub 2017 Dec 29. PMID: 29289937

Article Published Date : Dec 28, 2017

Study Type : Meta Analysis, Review

Additional Links

Diseases : Bone Fractures

Therapeutic Actions : Whole-Body Vibration

Additional Keywords : Risk Reduction

[+]

Vitamin D supplementation between 700 to 800 IU/d appears to reduce the risk of hip and any nonvertebral fractures in ambulatory or institutionalized elderly persons. May 11, 2005

Click here to read the entire abstract

Pubmed Data : JAMA. 2005 May 11;293(18):2257-64. PMID: 15886381

Article Published Date : May 11, 2005

Study Type : Meta Analysis

Additional Links

Substances : Vitamin D

Diseases : Bone Fractures, Hip Fracture

[+]

Vitamin K1 and K2 exhibit anti-fracture activity.Dec 01, 2009

Click here to read the entire abstract

Pubmed Data : Clin Calcium. 2009 Dec;19(12):1805-14. PMID: 19949272

Article Published Date : Dec 01, 2009

Study Type : Meta Analysis

Additional Links

Substances : Vitamin K2

Diseases : Bone Fractures, Osteoporosis

[+]

A protein-rich supplementation given to lean elderly female hip fracture patients increased the total body bone mineral density. Mar 01, 2011

Click here to read the entire abstract

Pubmed Data : Obes Surg. 2011 Mar;21(3):356-61. PMID: 17498850

Article Published Date : Mar 01, 2011

Study Type : Human Study

Additional Links

Substances : Protein Supplement

Diseases : Bone Fractures, Hip Fracture

[+]

Add-on yoga-based YPET accelerates fracture healing.Feb 28, 2011

Click here to read the entire abstract

Pubmed Data : J Altern Complement Med. 2011 Mar ;17(3):253-8. Epub 2011 Mar 9. PMID: 21417810

Article Published Date : Feb 28, 2011

Study Type : Human Study

Additional Links

Diseases : Bone Fractures, Fractures: Bone

Therapeutic Actions : Yoga

[+]

Adding vitamin K(2) to vitamin D(3) with calcium reduced the lifetime probability ofat least one fracture by 25%, increased discounted survival by 0.7 quality-adjusted life-years (QALYs). Mar 08, 2012

Click here to read the entire abstract

Pubmed Data : Osteoporos Int. 2012 Mar 8. Epub 2012 Mar 8. PMID: 22398856

Article Published Date : Mar 08, 2012

Study Type : Human Study

Additional Links

Substances : Vitamin K2

Diseases : Bone Fractures

[+]

Adjuvant treatment with aromatase inhibitors in breast cancer result in higher rates of hot flushes, musculoskeletal complaints, osteoporosis and fractures.Aug 01, 2006

Click here to read the entire abstract

Pubmed Data : Curr Med Res Opin. 2006 Aug;22(8):1609-21. PMID: 16870085

Article Published Date : Aug 01, 2006

Study Type : Human Study

Additional Links

Diseases : Bone Fractures, Breast Cancer, Drug-Induced Toxicity , Hot Flash, Musculoskeletal Complaints, Pain: Musculoskeletal

Additional Keywords : Drug: Tamoxifen

Problem Substances : Arimidex, Aromatase Inhibitor Drugs

[+]

Although hip bone mineral density is strongly related to hip fracture risk in elderly white women, other clinical risk factors also are independent predictors of long-term risk.Sep 01, 2004

Click here to read the entire abstract

Pubmed Data : J Am Geriatr Soc. 2004 Sep;52(9):1479-86. PMID: 15341549

Article Published Date : Sep 01, 2004

Study Type : Human Study

Additional Links

Diseases : Bone Fractures, Diabetes Mellitus: Type 2, Hip Fracture, Osteoporosis, Parkinson's Disease, Vision Loss

Additional Keywords : Diseases that are Linked

[+]

Among adults aged 70 or more, current levothyroxine treatment was associated with a significantly increased risk of fracture, with a strong dose-response relation. Jan 01, 2011

Click here to read the entire abstract

Pubmed Data : BMJ. 2011;342:d2238. Epub 2011 Apr 28. PMID: 21527461

Article Published Date : Jan 01, 2011

Study Type : Human Study

Additional Links

Diseases : Bone Fractures

Problem Substances : Levothyroxine

[+]

Bisphosphonate use in early breast cancer does not appeasr to reduce the number of fractures. Jan 08, 2010

Click here to read the entire abstract

Pubmed Data : Gynecol Oncol. 2010 Jan 8. Epub 2010 Jan 8. PMID: 20061004

Article Published Date : Jan 08, 2010

Study Type : Human Study

Additional Links

Diseases : Bone Fractures, Breast Cancer

Problem Substances : Bisphosphonates

[+]

Calcium supplementation (without vitamin D) is associated with increased risk of bone fracture.Aug 01, 2008

Click here to read the entire abstract

Pubmed Data : Osteoporos Int. 2008 Aug;19(8):1119-23. Epub 2008 Feb 20. PMID: 18286218

Article Published Date : Aug 01, 2008

Study Type : Human Study

Additional Links

Diseases : Bone Fractures, Osteoporosis

[+]

Community water fluoridation and rate of pediatric fractures. Sep 30, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Am Acad Orthop Surg Glob Res Rev. 2023 Oct 1 ;7(10). Epub 2023 Oct 5. PMID: 37796978

Article Published Date : Sep 30, 2023

Study Type : Human Study

Additional Links

Diseases : Bone Fractures, Fluoride Toxicity

Problem Substances : Sodium Fluoride

[+]

Cost analysis of photobiomodulation in tibia fracture in the Brazilian public health system.Dec 31, 2022

Click here to read the entire abstract

Pubmed Data : PLoS One. 2023 ;18(12):e0294290. Epub 2023 Dec 8. PMID: 38064443

Article Published Date : Dec 31, 2022

Study Type : Human Study

Additional Links

Diseases : Bone Fractures

Therapeutic Actions : Photobiomodulation

[+]

Dietary magnesium may play a role in musculoskeletal health.Oct 29, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2017 Oct 30 ;9(11). Epub 2017 Oct 30. PMID: 29084183

Article Published Date : Oct 29, 2017

Study Type : Human Study

Additional Links

Substances : Magnesium

Diseases : Bone Fractures, Osteoporosis, Sarcopenia

Pharmacological Actions : Osteoprotective

[+]

Effectiveness of 780 nm photobiomodulation as adjunct treatment for bone exposed fractures.Apr 30, 2024

Click here to read the entire abstract

Pubmed Data : J Biophotonics. 2024 May ;17(5):e202300348. Epub 2024 Feb 10. PMID: 38339853

Article Published Date : Apr 30, 2024

Study Type : Human Study

Additional Links

Diseases : Bone Fractures

Therapeutic Actions : Photobiomodulation

Pharmacological Actions : Analgesics, Anti-Inflammatory Agents

Additional Keywords : Medication Reduction

[+]

Excessive fluoride in water causes severe dental fluorosis and raises fracture risks, urging defluoridation in affected areas.Aug 31, 2024

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Ecotoxicol Environ Saf. 2024 Sep 1 ;282:116705. Epub 2024 Jul 13. PMID: 39003868

Article Published Date : Aug 31, 2024

Study Type : Human Study

Additional Links

Diseases : Bone Fractures, Fluorosis

Problem Substances : Fluoride

[+]

Fracture risk is increased in patients treated with loop diuretics.Jan 01, 2006

Click here to read the entire abstract

Pubmed Data : J Intern Med. 2006 Jan;259(1):117-24. PMID: 16336519

Article Published Date : Jan 01, 2006

Study Type : Human Study

Additional Links

Diseases : Bone Fractures, Hip Fracture

Problem Substances : Diuretic: Loop, Diuretic Drugs

[+]

High consumption of sugar-sweetened beverages Is associated with low bone mineral density in young people.Jan 08, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2023 Jan 9 ;15(2). Epub 2023 Jan 9. PMID: 36678194

Article Published Date : Jan 08, 2023

Study Type : Human Study

Additional Links

Diseases : Bone Fractures, High Sugar Diet, Osteopenia, Osteoporosis

Additional Keywords : Risk Factors

Problem Substances : Sugar Sweetened Beverages

[+]

Higher intake of black tea and particular classes of flavonoids were associated with lower risk of fracture related hospitalizations in elderly women at high risk of fracture.Aug 11, 2015

Click here to read the entire abstract

Pubmed Data : Am J Clin Nutr. 2015 Aug 12. Epub 2015 Aug 12. PMID: 26269364

Article Published Date : Aug 11, 2015

Study Type : Human Study

Additional Links

Substances : Black Tea, Flavonoids

Diseases : Bone Fractures

Additional Keywords : Risk Reduction

[+]

Higher testosterone levels in both genders and higher DHEA-S levels in women predicted a more than 60% lower risk of falling. Sep 01, 2008

Click here to read the entire abstract

Pubmed Data : Osteoporos Int. 2008 Sep;19(9):1307-14. Epub 2008 Mar 20. PMID: 18351428

Article Published Date : Sep 01, 2008

Study Type : Human Study

Additional Links

Substances : DHEA (Dehydroepiandrosterone), Testosterone

Diseases : Bone Fractures

[+]

Hypnosis may be capable of enhancing both anatomical and functional fracture healing.Mar 01, 1999

Click here to read the entire abstract

Pubmed Data : Altern Ther Health Med. 1999 Mar;5(2):67-75. PMID: 10069091

Article Published Date : Mar 01, 1999

Study Type : Human Study

Additional Links

Diseases : Bone Fractures

Therapeutic Actions : Hypnosis

[+]

Lepidium sativum seeds has a marked influence on fracture healing in rabbits.Apr 30, 2007

Click here to read the entire abstract

Pubmed Data : MedGenMed. 2007 Apr 30;9(2):23. PMID: 17955079

Article Published Date : Apr 30, 2007

Study Type : Human Study

Additional Links

Substances : Garden Cress (Lepidium sativum)

Diseases : Bone Fractures

[+]

Long-term proton pump inhibitor therapy is associated with an increased risk of hip fracture.Dec 27, 2006

Click here to read the entire abstract

Pubmed Data : JAMA. 2006 Dec 27;296(24):2947-53. PMID: 17190895

Article Published Date : Dec 27, 2006

Study Type : Human Study

Additional Links

Diseases : Bone Fractures, Hip Fracture, Osteoporosis

Problem Substances : Proton-Pump Inhibitors

[+]

Low plasma vitamin D levels are associated with osteoporotic fractures.Apr 07, 2020

Click here to read the entire abstract

Pubmed Data : Clin Chem. 2020 Apr 7. Epub 2020 Apr 7. PMID: 32255480

Article Published Date : Apr 07, 2020

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Bone Fractures

[+]

Low-frequency vibratory exercise reduces the risk of bone fracture more than walking.Nov 29, 2006

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Musculoskelet Disord. 2006 Nov 30 ;7:92. Epub 2006 Nov 30. PMID: 17137514

Article Published Date : Nov 29, 2006

Study Type : Human Study

Additional Links

Diseases : Bone Fractures

Therapeutic Actions : Whole-Body Vibration

Additional Keywords : Risk Reduction

[+]

Low-intensity pulse ultrasound stimulation could accelerate fracture healing of the distal radius and promote local bone formation.Oct 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Acta Cir Bras. 2014 Nov ;29(11):765-70. PMID: 25424299

Article Published Date : Oct 31, 2014

Study Type : Human Study

Additional Links

Diseases : Bone Fractures

Therapeutic Actions : Ultrasound therapy

Pharmacological Actions : Osteogenic

Additional Keywords : Significant Treatment Outcome

[+]

Menaquinone-7 (vitamin K2) supplementation increases osteocalcin carboxylation associated with improved bone quality.Oct 01, 2009

Click here to read the entire abstract

Pubmed Data : Br J Nutr. 2009 Oct;102(8):1171-8. Epub 2009 May 19. PMID: 19450370

Article Published Date : Oct 01, 2009

Study Type : Human Study

Additional Links

Substances : Vitamin K2: Menaquinone-7

Diseases : Bone Fractures, Osteoporosis

[+]

Most of the increase in mortality following hip and pelvic fractures is due to underlying conditions and probably would not be affected by reductions in the incidence of these fractures.Jul 22, 1996

Click here to read the entire abstract

Pubmed Data : Arch Intern Med. 1996 Jul 22;156(14):1521-5. PMID: 8687260

Article Published Date : Jul 22, 1996

Study Type : Human Study

Additional Links

Diseases : Bone Fractures, Elderly: Age Specific Diseases, Hip Fracture, Osteoporosis

Additional Keywords : Osteoporosis Myths

[+]

Neuromuscular and visual impairments (as well as femoral-neck BMD) are significant and independent predictors of the risk of hip fracture in elderly women. Jul 20, 1996

Click here to read the entire abstract

Pubmed Data : Lancet. 1996 Jul 20;348(9021):145-9. PMID: 8684153

Article Published Date : Jul 20, 1996

Study Type : Human Study

Additional Links

Diseases : Bone Fractures, Hip Fracture, Osteoporosis

Additional Keywords : Osteoporosis Myths

[+]

Nonvertebral fracture prevention with vitamin D is dose dependent,Mar 23, 2009

Click here to read the entire abstract

Pubmed Data : Arch Intern Med. 2009 Mar 23;169(6):551-61. PMID: 19307517

Article Published Date : Mar 23, 2009

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Bone Fractures

Additional Keywords : Risk Reduction

[+]

one-year treatment with melatonin increased bone mineral density at femoral neck in a dose-dependent manner, while high dose melatonin increased vBMD in the spine.Jun 02, 2015

Click here to read the entire abstract

Pubmed Data : J Pineal Res. 2015 Jun 3. Epub 2015 Jun 3. PMID: 26036434

Article Published Date : Jun 02, 2015

Study Type : Human Study

Additional Links

Substances : Melatonin

Diseases : Bone Fractures, Osteopenia, Osteoporosis

Pharmacological Actions : Osteogenic

Additional Keywords : Dose Response, Significant Treatment Outcome

[+]

Participation in once per week tai chi classes for 16 weeks can prevent falls in relatively healthy community-dwelling older people.Aug 01, 2007

Click here to read the entire abstract

Pubmed Data : J Am Geriatr Soc. 2007 Aug;55(8):1185-91. PMID: 17661956

Article Published Date : Aug 01, 2007

Study Type : Human Study

Additional Links

Diseases : Bone Fractures

Therapeutic Actions : Tai Chi

Additional Keywords : Risk Reduction

[+]

Physical activity based on dance may improve balance and hence be a useful tool in reducing the risk of falling in the elderly.Oct 01, 2005

Click here to read the entire abstract

Pubmed Data : Aging Clin Exp Res. 2005 Oct;17(5):385-9. PMID: 16392413

Article Published Date : Oct 01, 2005

Study Type : Human Study

Additional Links

Diseases : Aging, Bone Fractures, Hip Fracture

Therapeutic Actions : Dancing

[+]

Pulsed electromagnetic field therapy has positive significance for improving pain, body functional changes, and bone loss after vertebral fracture surgery.Dec 31, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Res Int. 2021 ;2021:4650057. Epub 2021 Jul 16. PMID: 34327227

Article Published Date : Dec 31, 2020

Study Type : Human Study

Additional Links

Diseases : Bone Fractures

Therapeutic Actions : Pulsed EMF field (PEMF)

[+]

Reduction in tibial shaft fracture healing time with essential nutrient supplementation containing ascorbic acid, lysine, and proline.Dec 01, 2004

Click here to read the entire abstract

Pubmed Data : J Altern Complement Med. 2004 Dec;10(6):915-6. PMID: 15729747

Article Published Date : Dec 01, 2004

Study Type : Human Study

Additional Links

Substances : Lysine, Proline, Vitamin C

Diseases : Bone Fractures

Additional Keywords : Special

[+]

Rosiglitazone and pioglitazone increase fracture risk in women and men with type 2 diabetes.Aug 01, 2010

Click here to read the entire abstract

Pubmed Data : Diabetes Obes Metab. 2010 Aug;12(8):716-21. PMID: 20590749

Article Published Date : Aug 01, 2010

Study Type : Human Study

Additional Links

Diseases : Bone Fractures, Diabetes Mellitus: Type 2, Hip Fracture, Osteoporosis

Problem Substances : Rosiglitazone (trade name Avandia)

[+]

Soy food consumption may reduce the risk of fracture in postmenopausal women, particularly among those in the early years following menopause.Sep 12, 2005

Click here to read the entire abstract

Pubmed Data : Arch Intern Med. 2005 Sep 12;165(16):1890-5. PMID: 16157834

Article Published Date : Sep 12, 2005

Study Type : Human Study

Additional Links

Substances : Soy

Diseases : Bone Fractures, Osteoporosis

Additional Keywords : Risk Reduction

[+]

Statin use may exacerbate muscle performance declines and falls risk associated with aging without a concomitant decrease in muscle mass.Sep 01, 2009

Click here to read the entire abstract

Pubmed Data : QJM. 2009 Sep ;102(9):625-33. Epub 2009 Jul 24. PMID: 19633029

Article Published Date : Sep 01, 2009

Study Type : Human Study

Additional Links

Diseases : Bone Fractures, Hip Fracture, Muscle Fatigue, Statin-Induced Pathologies

Pharmacological Actions : Anticholesteremic Agents

Problem Substances : Statin Drugs

[+]

Statin users have poorer leaning balance which may potentially increase fall risk in this group.Oct 27, 2011

Click here to read the entire abstract

Pubmed Data : Intern Med J. 2011 Oct 27. Epub 2011 Oct 27. PMID: 22032261

Article Published Date : Oct 27, 2011

Study Type : Human Study

Additional Links

Diseases : Balance Disorders, Bone Fractures

Problem Substances : Statin Drugs

[+]

Strontium renalate is a safe and effective treatment for veterbral and hip osteoporosis.Mar 01, 2005

Click here to read the entire abstract

Pubmed Data : Curr Osteoporos Rep. 2005 Mar;3(1):30-4. PMID: 16036099

Article Published Date : Mar 01, 2005

Study Type : Human Study

Additional Links

Substances : Strontium

Diseases : Bone Fractures, Hip Fracture, Osteoporosis

Additional Keywords : Risk Reduction

[+]

Subtrochanteric stress fractures in patients on oral bisphosphonate therapy is an emerging problem. Oct 01, 2011

Click here to read the entire abstract

Pubmed Data : Acta Orthop Belg. 2011 Oct ;77(5):632-7. PMID: 22187839

Article Published Date : Oct 01, 2011

Study Type : Human Study

Additional Links

Diseases : Bone Fractures, Subtrochanteric stress fractures

Problem Substances : Bisphosphonates

[+]

Tai Chi decreases the number of falls, the risk for falling, and the fear of falling, and it improves functional balance and physical performance in physically inactive persons aged 70 years or older.Feb 01, 2005

Click here to read the entire abstract

Pubmed Data : J Gerontol A Biol Sci Med Sci. 2005 Feb;60(2):187-94. PMID: 15814861

Article Published Date : Feb 01, 2005

Study Type : Human Study

Additional Links

Diseases : Bone Fractures

Therapeutic Actions : Tai Chi

[+]

The majority of those patients who will sustain a low-trauma fracture do not meet the T-score definition of osteoporosis. Conversely, younger individuals with BD in the osteoporotic range but no other risk factors have relatively low rates of fracture.Mar 01, 2012

Click here to read the entire abstract

Pubmed Data : Curr Osteoporos Rep. 2012 Mar ;10(1):28-41. PMID: 22274642

Article Published Date : Mar 01, 2012

Study Type : Human Study

Additional Links

Diseases : Bone Fractures, Osteopenia, Osteoporosis

Additional Keywords : T-Score/Z-Score Mythology

[+]

This study found that vitamin K intake greater than the current adequate intake would be required for bone health.Dec 31, 2014

Click here to read the entire abstract

Pubmed Data : Clin Calcium. 2015 ;25(7):983-90. PMID: 26119310

Article Published Date : Dec 31, 2014

Study Type : Human Study

Additional Links

Substances : Vitamin K

Diseases : Bone Fractures

Additional Keywords : Risk Reduction

[+]

Vitamin D status appears inversely related to fractures in middle aged adults.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2016 ;11(10):e0164160. Epub 2016 Aug 17. PMID: 27749911

Article Published Date : Dec 31, 2015

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Aging, Bone Fractures, Vitamin D Deficiency

Additional Keywords : Risk Factors

[+]

Vitamin K supplementation in postmenopausal women wih osteopenia appears to protect against bone fractures and cancers. Oct 14, 2008

Click here to read the entire abstract

Pubmed Data : PLoS Med. 2008 Oct 14;5(10):e196. PMID: 18922041

Article Published Date : Oct 14, 2008

Study Type : Human Study

Additional Links

Substances : Vitamin K

Diseases : Bone Fractures, Cancers: All, Osteopenia

Pharmacological Actions : Chemopreventive

Additional Keywords : Risk Reduction

[+]

Vitamin K2 (MK-4) may be beneficial in the maintenance of bone health in postmenopausal women.Feb 01, 2009

Click here to read the entire abstract

Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2009 Feb;55(1):15-21. PMID: 19352059

Article Published Date : Feb 01, 2009

Study Type : Human Study

Additional Links

Substances : Vitamin K2, Vitamin K2: (MK-4)

Diseases : Bone Fractures, Osteoporosis, Postmenopausal Disorders

[+]

vitamin Vitamin (2) works synergistically with alendronate on improving both osteocalcin carboxylation and BMD of femoral neck in postmenopausal women with osteoporosis.Jan 01, 2008

Click here to read the entire abstract

Pubmed Data : J Bone Miner Metab. 2008;26(3):260-4. Epub 2008 May 11. PMID: 18470667

Article Published Date : Jan 01, 2008

Study Type : Human Study

Additional Links

Substances : Vitamin K2

Diseases : Bone Fractures, Osteoporosis

Additional Keywords : Drug Synergy

[+]

Zinc supplementation stimulates fracture healing. Sep 01, 2008

Click here to read the entire abstract

Pubmed Data : Saudi Med J. 2008 Sep;29(9):1276-9. PMID: 18813411

Article Published Date : Sep 01, 2008

Study Type : Human Study

Additional Links

Substances : Zinc

Diseases : Bone Fractures

[+]

Effect of near-infrared light on in vitro cellular ATP production of osteoblasts and fibroblasts and on fracture healing.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Clin Orthop Trauma. 2016 ;7(4):234-241. Epub 2016 Mar 10. PMID: 27857496

Article Published Date : Dec 31, 2015

Study Type : Animal Study, In Vitro Study

Additional Links

Diseases : Bone Fractures

Therapeutic Actions : Infrared Light, Photobiomodulation

[+]

1,25-Dihydroxyvitamin D suppresses M1 macrophages and promotes M2 differentiation at bone injury sites.Jan 05, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : JCI Insight. 2018 09 6 ;3(17). Epub 2018 Sep 6. PMID: 30185660

Article Published Date : Jan 05, 2018

Study Type : Animal Study

Additional Links

Substances : Vitamin D

Diseases : Bone Fractures, Wound Healing

Pharmacological Actions : Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

A mineral-rich extract from the red marine algae Lithothamnion calcareum preserves bone structure and function in female mice on a Western-style diet.Apr 01, 2010

Click here to read the entire abstract

Pubmed Data : Calcif Tissue Int. 2010 Apr;86(4):313-24. Epub 2010 Feb 24. PMID: 20180099

Article Published Date : Apr 01, 2010

Study Type : Animal Study

Additional Links

Substances : Red Marine Algae

Diseases : Bone Fractures, Hip Fracture, Osteoporosis, Western-Style Diet Induced Toxicity

Anti Therapeutic Actions : Western Diet

[+]

A review of photobiomodulation therapy in bone repair.Oct 31, 2019

Click here to read the entire abstract

Pubmed Data : Injury. 2019 Nov ;50(11):1853-1867. Epub 2019 Sep 21. PMID: 31585673

Article Published Date : Oct 31, 2019

Study Type : Animal Study

Additional Links

Diseases : Bone Fractures

Therapeutic Actions : Photobiomodulation

Additional Keywords : Bone Regeneration

[+]

Accelerated bone regeneration by an astaxanthin-modified antioxidant aerogel.Sep 07, 2022

Click here to read the entire abstract

Pubmed Data : ACS Biomater Sci Eng. 2022 Sep 8. Epub 2022 Sep 8. PMID: 36073984

Article Published Date : Sep 07, 2022

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Bone Fractures

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Bone Regeneration

[+]

Acupuncture can increase the level of brain-derived neutrophic factor and accelerate the process of fracture healing. Apr 01, 2009

Click here to read the entire abstract

Pubmed Data : Zhongguo Zhen Jiu. 2009 Apr;29(4):303-8. PMID: 19565740

Article Published Date : Apr 01, 2009

Study Type : Animal Study

Additional Links

Diseases : Bone Fractures

Therapeutic Actions : Acupuncture

[+]

Amygdalin promotes fracture healing through TGF- β/Smad signaling in mesenchymal stem cells.Dec 31, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Stem Cells Int. 2020 ;2020:8811963. Epub 2020 Sep 7. PMID: 32963548

Article Published Date : Dec 31, 2019

Study Type : Animal Study

Additional Links

Substances : Amygdalin

Diseases : Bone Fractures

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation

[+]

Cannabidiol and cannabigerol, non-psychotropic cannabinoids, as analgesics that effectively manage bone fracture pain and promote healing.Aug 18, 2023

Click here to read the entire abstract

Pubmed Data : J Bone Miner Res. 2023 Aug 19. Epub 2023 Aug 19. PMID: 37597163

Article Published Date : Aug 18, 2023

Study Type : Animal Study

Additional Links

Substances : Cannabidiol, Cannabigerol

Diseases : Bone Fractures

Pharmacological Actions : Analgesics, Anti-Inflammatory Agents

[+]

CBD leads to improvement in fracture healing and demonstrate the critical mechanical role of collagen crosslinking enzymes.Mar 18, 2015

Click here to read the entire abstract

Pubmed Data : J Bone Miner Res. 2015 Mar 19. Epub 2015 Mar 19. PMID: 25801536

Article Published Date : Mar 18, 2015

Study Type : Animal Study

Additional Links

Substances : Cannabidiol

Diseases : Bone Fractures

Pharmacological Actions : Enzyme Activators

[+]

Chaste berry positvely effects bone fracture healing in rabbits. Apr 01, 1998

Click here to read the entire abstract

Pubmed Data : Carcinogenesis. 1998 Apr;19(4):611-6. PMID: 18306063

Article Published Date : Apr 01, 1998

Study Type : Animal Study

Additional Links

Substances : Chaste Tree (Chasteberry)

Diseases : Bone Fractures

[+]

Curcumin improves bone microarchitecture and enhances mineral density in transgenic mice.Jan 15, 2011

Click here to read the entire abstract

Pubmed Data : Phytomedicine. 2011 Jan 15;18(2-3):205-13. Epub 2010 Jul 16. PMID: 20637579

Article Published Date : Jan 15, 2011

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Bone Fractures, Osteopenia, Osteoporosis

Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Dietary flavonoid kaempferol inhibits glucocorticoid-induced bone loss by promoting osteoblast survival.Feb 12, 2018

Click here to read the entire abstract

Pubmed Data : Nutrition. 2018 Feb 13 ;53:64-76. Epub 2018 Feb 13. PMID: 29655780

Article Published Date : Feb 12, 2018

Study Type : Animal Study

Additional Links

Substances : Kaempferol

Diseases : Bone Fractures

Pharmacological Actions : Osteoprotective

[+]

Dietary supplementation with conditionally essential amino acids in malnourished animals enhanced fracture and soft-tissue healing. Nov 01, 2006

Click here to read the entire abstract

Pubmed Data : J Bone Joint Surg Am. 2006 Nov;88(11):2386-94. PMID: 17079395

Article Published Date : Nov 01, 2006

Study Type : Animal Study

Additional Links

Substances : Amino Acids, Protein Supplement

Diseases : Bone Fractures

[+]

Echinacoside promotes osteogenesis and angiogenesis and inhibits osteoclast formation.Mar 18, 2024

Click here to read the entire abstract

Pubmed Data : Eur J Clin Invest. 2024 Mar 19:e14198. Epub 2024 Mar 19. PMID: 38501711

Article Published Date : Mar 18, 2024

Study Type : Animal Study

Additional Links

Substances : Echinacea

Diseases : Bone Fractures

Pharmacological Actions : Angiogenesis Inducing Agents, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Matrix metalloproteinase-9 (MMP-9) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Effect of low-level laser therapy on the fracture healing process.Dec 31, 2009

Click here to read the entire abstract

Pubmed Data : Lasers Med Sci. 2010 Jan ;25(1):73-7. Epub 2009 Apr 28. PMID: 19399356

Article Published Date : Dec 31, 2009

Study Type : Animal Study

Additional Links

Diseases : Bone Fractures

Therapeutic Actions : Photobiomodulation

Additional Keywords : Bone Regeneration

[+]

Effects of concurrent use of royal jelly with hydroxyapatite on bone healing.Jun 30, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Heliyon. 2020 Jul ;6(7):e04547. Epub 2020 Jul 30. PMID: 32775723

Article Published Date : Jun 30, 2020

Study Type : Animal Study

Additional Links

Substances : Royal Jelly

Diseases : Bone Fractures

Pharmacological Actions : Osteogenic

[+]

Fluoroquinolones retard fracture healing in rats. Jan 01, 2005

Click here to read the entire abstract

Pubmed Data : Ulus Travma Acil Cerrahi Derg. 2005 Jan;11(1):17-22. PMID: 15688263

Article Published Date : Jan 01, 2005

Study Type : Animal Study

Additional Links

Diseases : Bone Fractures, Hip Fracture

Problem Substances : Fluoroquinolone Antibiotic

[+]

Genistein is superior to the bone drugs alendronate, raloxifene and estradiol in osteoporotic, ovariectomized rats. Nov 01, 2008

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Br J Pharmacol. 2008 Nov;155(6):896-905. Epub 2008 Aug 11. PMID: 18695641

Article Published Date : Nov 01, 2008

Study Type : Animal Study

Additional Links

Substances : Genistein

Diseases : Bone Fractures, Osteopenia, Osteoporosis

Additional Keywords : Ovariectomy-Induced Changes, Superiority of Natural Substances versus Drugs

[+]

High concentration of matrix AGEs may slow down the bone formation process in vivo.May 29, 2016

Click here to read the entire abstract

Pubmed Data : Calcif Tissue Int. 2016 May 30. Epub 2016 May 30. PMID: 27240574

Article Published Date : May 29, 2016

Study Type : Animal Study

Additional Links

Diseases : Advanced Glycation End products (AGE), Bone Fractures

[+]

High dose vitamin D3 stimulates fracture healing.Jan 01, 1997

Click here to read the entire abstract

Pubmed Data : Arch Orthop Trauma Surg. 1997;116(1-2):37-40. PMID: 9006763

Article Published Date : Jan 01, 1997

Study Type : Animal Study

Additional Links

Substances : Vitamin D

Diseases : Bone Fractures

[+]

High-dose vitamin D3 application had positive effects on fracture healing in a healthy animal model. Jan 01, 1997

Click here to read the entire abstract

Pubmed Data : Arch Orthop Trauma Surg. 1997;116(5):271-4. PMID: 9177802

Article Published Date : Jan 01, 1997

Study Type : Animal Study

Additional Links

Substances : Vitamin D

Diseases : Bone Fractures

[+]

Hyperbaric oxygen therapy treatment of open tibial fractures in seawater can reduce the inflammatory reaction and reperfusion injury.Apr 30, 2017

Click here to read the entire abstract

Pubmed Data : Undersea Hyperb Med. 2017 May-Jun;44(3):235-242. PMID: 28779580

Article Published Date : Apr 30, 2017

Study Type : Animal Study

Additional Links

Diseases : Bone Fractures

Therapeutic Actions : Hyperbaric Treatment

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Lepidium sativum extract that accelerated bone healing by increasing osteoblastic proliferation.Jan 31, 2020

Click here to read the entire abstract

Pubmed Data : J Family Med Prim Care. 2020 Feb ;9(2):812-818. Epub 2020 Feb 28. PMID: 32318426

Article Published Date : Jan 31, 2020

Study Type : Animal Study

Additional Links

Substances : Garden Cress (Lepidium sativum)

Diseases : Bone Fractures

Pharmacological Actions : Osteogenic

[+]

Local application of tanshinone IIA protects mesenchymal stem cells from apoptosis and promotes fracture healing.May 22, 2024

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Orthop Surg Res. 2024 May 23 ;19(1):309. Epub 2024 May 23. PMID: 38783358

Article Published Date : May 22, 2024

Study Type : Animal Study

Additional Links

Substances : Tanshinone IIA

Diseases : Bone Fractures

Pharmacological Actions : Anti-Apoptotic, Antioxidants

Additional Keywords : Ovariectomy-Induced Changes

[+]

Mangiferin enhances endochondral ossification-based bone repair in massive bone defect.Mar 15, 2018

Click here to read the entire abstract

Pubmed Data : FASEB J. 2018 Mar 16:fj201701411R. Epub 2018 Mar 16. PMID: 29547701

Article Published Date : Mar 15, 2018

Study Type : Animal Study

Additional Links

Substances : Mangiferin

Diseases : Bone Fractures

Pharmacological Actions : Autophagy Inhibitors

Additional Keywords : Bone Regeneration

[+]

Naringin promotes fracture healing through stimulation of angiogenesis.Jan 04, 2017

Click here to read the entire abstract

Pubmed Data : Chem Biol Interact. 2017 Jan 5 ;261:11-17. Epub 2016 Nov 8. PMID: 27833010

Article Published Date : Jan 04, 2017

Study Type : Animal Study

Additional Links

Substances : Citrus naringin

Diseases : Bone Fractures, Osteoporosis

Pharmacological Actions : Angiogenesis Inducing Agents

[+]

Oral administration of bovine lactoferrin accelerates the healing of fracture in ovariectomized rats.Apr 28, 2020

Click here to read the entire abstract

Pubmed Data : J Bone Miner Metab. 2020 Apr 29. Epub 2020 Apr 29. PMID: 32350616

Article Published Date : Apr 28, 2020

Study Type : Animal Study

Additional Links

Substances : Lactoferrin

Diseases : Bone Fractures

Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Bone Regeneration

[+]

Propolis improves bone fracture healing time. Mar 21, 2011

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2011 Mar 21. Epub 2011 Mar 21. PMID: 21425375

Article Published Date : Mar 21, 2011

Study Type : Animal Study

Additional Links

Substances : Bee Propolis

Diseases : Bone Fractures

[+]

Protective effects of caffeic acid phenethyl ester and thymoquinone against cigarette smoke.Aug 31, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Oral Biol Craniofac Res. 2022 Sep-Oct;12(5):610-616. Epub 2022 Aug 14. PMID: 35989976

Article Published Date : Aug 31, 2022

Study Type : Animal Study

Additional Links

Substances : Caffeic acid phenethyl ester

Diseases : Bone Fractures

Pharmacological Actions : Osteoprotective

[+]

Quercetin may speed fracture healing by increasing bone formation. Aug 01, 2008

Click here to read the entire abstract

Pubmed Data : J Orthop Res. 2008 Aug;26(8):1061-6. PMID: 18383168

Article Published Date : Aug 01, 2008

Study Type : Animal Study

Additional Links

Substances : Quercetin

Diseases : Bone Fractures

[+]

Red sage (Radix Salviae M.) could affect the procollagens expression to enhance the healing of bone fracture. Apr 01, 2000

Click here to read the entire abstract

Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 2000 Apr;20(4):269-71. PMID: 11789264

Article Published Date : Apr 01, 2000

Study Type : Animal Study

Additional Links

Substances : Red Sage

Diseases : Bone Fractures

[+]

Red sage (Radix Salviae M.) increases the strength of fracture healing site.Jan 05, 2007

Click here to read the entire abstract

Pubmed Data : Toxicology. 2007 Jan 5;229(1-2):62-72. Epub 2006 Oct 17. PMID: 11783293

Article Published Date : Jan 05, 2007

Study Type : Animal Study

Additional Links

Substances : Red Sage

Diseases : Bone Fractures

[+]

Royal jelly stimulates bone formation. - Article 2Jul 01, 2007

Click here to read the entire abstract

Pubmed Data : J Nutr. 2007 Jul;137(7):1769-75. PMID: 16951718

Article Published Date : Jul 01, 2007

Study Type : Animal Study

Additional Links

Substances : Royal Jelly

Diseases : Bone Fractures, Osteoporosis

[+]

Synthetic vitamin A induces hemorrhaging and bone toxicity in rats fed a diet deficient in vitamin K. Feb 01, 1989

Click here to read the entire abstract

Pubmed Data : Toxicol Appl Pharmacol. 1989 Feb;97(2):300-10. PMID: 2922761

Article Published Date : Feb 01, 1989

Study Type : Animal Study

Additional Links

Diseases : Bone Fractures, Vitamin K Deficiency

Problem Substances : 13-cis-retinoic acid , Retinyl Acetate

[+]

Tanshinone IIA exerts beneficial effects on fracture healing in vitro and in vivo.Aug 31, 2019

Click here to read the entire abstract

Pubmed Data : Chem Biol Interact. 2019 Sep 1 ;310:108748. Epub 2019 Jul 12. PMID: 31306638

Article Published Date : Aug 31, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Tanshinone IIA

Diseases : Bone Fractures

Pharmacological Actions : MicroRNA modulator

[+]

The application of magnetic fields have a positive effect on fracture healing.May 01, 2006

Click here to read the entire abstract

Pubmed Data : Radiat Res. 2006 May;165(5):546-52. PMID: 15503621

Article Published Date : May 01, 2006

Study Type : Animal Study

Additional Links

Diseases : Bone Fractures

Therapeutic Actions : Magnet Therapy

[+]

The homeopathic dilution known as plumbum metallicum 30c is superior to calcitonin in regenerating bone in an animal study. Apr 01, 2009

Click here to read the entire abstract

Pubmed Data : Homeopathy. 2009 Apr;98(2):92-6. PMID: 19358962

Article Published Date : Apr 01, 2009

Study Type : Animal Study

Additional Links

Substances : Plumbum metallicum

Diseases : Bone Fractures

Therapeutic Actions : Homeopathic Treatment

Additional Keywords : Superiority of Natural Substances versus Drugs

[+]

The phytoestrogen equol is able to improve fracture healing in ovariectomy-induced osteoporotic bones. Apr 01, 2009

Click here to read the entire abstract

Pubmed Data : Planta Med. 2009 Apr;75(5):459-65. Epub 2009 Feb 24. PMID: 19241330

Article Published Date : Apr 01, 2009

Study Type : Animal Study

Additional Links

Substances : Equol, phytoestrogens

Diseases : Bone Fractures

[+]

The phytoestrogen puerarin may increase bone formation. Aug 01, 2007

Click here to read the entire abstract

Pubmed Data : Osteoarthritis Cartilage. 2007 Aug;15(8):894-9. Epub 2007 Mar 26. PMID: 17379543

Article Published Date : Aug 01, 2007

Study Type : Animal Study

Additional Links

Substances : Puerarin

Diseases : Bone Fractures

[+]

The sulfated polysaccharide fucoidan stimulates osteogenic differentiation of human adipose-derived stem cells, indicating it may it may be a potential candidate for promoting bone regeneration.Aug 09, 2012

Click here to read the entire abstract

Pubmed Data : Stem Cells Dev. 2012 Aug 10 ;21(12):2204-11. Epub 2011 Dec 19. PMID: 22050637

Article Published Date : Aug 09, 2012

Study Type : Animal Study

Additional Links

Substances : Fucoidan

Diseases : Bone Destructive Diseases: Over-Active Osteoclasts, Bone Fractures, Hip Fracture, Osteoporosis

Pharmacological Actions : Osteogenic

Additional Keywords : Bone Regeneration

[+]

These findings indicated the turmeric ability to facilitate bone hemostasis and optimize the expression of key markers involved in the bone metabolism. Apr 30, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Avicenna J Phytomed. 2022 May-Jun;12(3):197-212. PMID: 36186936

Article Published Date : Apr 30, 2022

Study Type : Animal Study

Additional Links

Substances : Turmeric

Diseases : Bone Fractures

Pharmacological Actions : Osteogenic

[+]

These results support the use of T. cordifolia in Indian ethnomedicine for the treatment of bone diseases and fractures.Feb 28, 2017

Click here to read the entire abstract

Pubmed Data : Biomed Pharmacother. 2017 Mar ;87:342-354. Epub 2017 Jan 5. PMID: 28064107

Article Published Date : Feb 28, 2017

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Guduchi

Diseases : Bone Fractures, Osteoarthritis

Pharmacological Actions : Osteoprotective

Additional Keywords : Plant Extracts

[+]

Treatment with Prunus dulcis extract with a dosage of 300 mg/kg accelerated tibial bone healing in rabbits.Jun 06, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Orthop Surg Res. 2021 Jun 7 ;16(1):362. Epub 2021 Jun 7. PMID: 34098995

Article Published Date : Jun 06, 2021

Study Type : Animal Study

Additional Links

Substances : Almond

Diseases : Bone Fractures

Pharmacological Actions : Antioxidants

[+]

Velvet antler polypeptides promoted proliferation of chondrocytes and osteoblast precursors and fracture healing.Mar 01, 1999

Click here to read the entire abstract

Pubmed Data : Zhongguo Yao Li Xue Bao. 1999 Mar;20(3):279-82. PMID: 10452108

Article Published Date : Mar 01, 1999

Study Type : Animal Study

Additional Links

Substances : Velvet antler

Diseases : Bone Fractures

[+]

Vitamin C contributes to accelerated healing of experimental fractures.Jul 01, 2001

Click here to read the entire abstract

Pubmed Data : Arch Orthop Trauma Surg. 2001 Jul;121(7):426-8. PMID: 11510911

Article Published Date : Jul 01, 2001

Study Type : Animal Study

Additional Links

Substances : Vitamin C

Diseases : Bone Fractures

[+]

Vitamin C contributes to healing bone fractures. Mar 01, 2007

Click here to read the entire abstract

Pubmed Data : J Bone Joint Surg Br. 2007 Mar;89(3):402-7. PMID: 17356161

Article Published Date : Mar 01, 2007

Study Type : Animal Study

Additional Links

Substances : Vitamin C

Diseases : Bone Fractures

[+]

Vitamin C may have a positive effect on fracture healing. Sep 01, 2007

Click here to read the entire abstract

Pubmed Data : Arch Orthop Trauma Surg. 2007 Sep;127(7):493-501. Epub 2007 Jul 17. PMID: 17639432

Article Published Date : Sep 01, 2007

Study Type : Animal Study

Additional Links

Substances : Vitamin C

Diseases : Bone Fractures

[+]

"Emergent adverse effects of proton pump inhibitors."Dec 09, 2012

Click here to read the entire abstract

Pubmed Data : Presse Med. 2012 Dec 10. Epub 2012 Dec 10. PMID: 23237784

Article Published Date : Dec 09, 2012

Study Type : Review

Additional Links

Diseases : Bone Fractures, Neutropenia: Drug-Induced, Osteoporosis, Stomach Cancer

Problem Substances : Proton-Pump Inhibitors

[+]

A placebo-controlled trial of primary prevention involving more than 4,000 patients showed no reduction in the risk of fracture after 4 years of treatment with alendronic acid.Jun 01, 2000

Click here to read the entire abstract

Pubmed Data : Prescrire Int. 2000 Jun;9(47):70-2. PMID: 11010741

Article Published Date : Jun 01, 2000

Study Type : Review

Additional Links

Diseases : Bone Fractures, Osteoporosis

Additional Keywords : Drugs that Don't Work

Problem Substances : Alendronate (trade name Fosamax)

[+]

Adequate magnesium supplementation should be considered as an important aspect of vitamin D therapy.May 02, 2017

Click here to read the entire abstract

Pubmed Data : Am J Ther. 2017 May 3. Epub 2017 May 3. PMID: 28471760

Article Published Date : May 02, 2017

Study Type : Review

Additional Links

Substances : Magnesium

Diseases : Bone Fractures, Dementia, Vitamin D Deficiency

Additional Keywords : Risk Reduction

[+]

Assessing optimal dietary intake of vitamin D for reducing fracture riskMay 16, 2012

Click here to read the entire abstract

Pubmed Data : Calcif Tissue Int. 2012 May 17. Epub 2012 May 17. PMID: 22592290

Article Published Date : May 16, 2012

Study Type : Review

Additional Links

Substances : Vitamin D

Diseases : Bone Fractures, Hip Fracture

Additional Keywords : Vitamin D Dosage

[+]

Cow milk consumption may adversely effect the risk of ovarian and prostate cancer and bone fracture risk.May 01, 2009

Click here to read the entire abstract

Pubmed Data : Am J Clin Nutr. 2009 May;89(5):1638S-1642S. Epub 2009 Mar 25. PMID: 19321571

Article Published Date : May 01, 2009

Study Type : Commentary

Additional Links

Diseases : Bone Fractures, Osteoporosis, Ovarian Cancer, Prostate Cancer

Problem Substances : Cow Milk

[+]

Daily supplementation with 500mg of vitamin C per day for 50 days decreases the 1-year risk of CRPS-I after wrist fracture.Mar 04, 2017

Click here to read the entire abstract

Pubmed Data : Orthop Traumatol Surg Res. 2017 Mar 5. Epub 2017 Mar 5. PMID: 28274883

Article Published Date : Mar 04, 2017

Study Type : Review

Additional Links

Substances : Vitamin C

Diseases : Bone Fractures, Complex Regional Pain Syndrome: Type I

Additional Keywords : Risk Reduction

[+]

Effect of vitamin B6 on osteoporosis fracture.Apr 30, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Bone Metab. 2023 May ;30(2):141-147. Epub 2023 May 31. PMID: 37449347

Article Published Date : Apr 30, 2023

Study Type : Review

Additional Links

Substances : Vitamin B6

Diseases : Bone Fractures, Osteoporosis

Pharmacological Actions : Osteoprotective

[+]

Effects of panax notoginseng saponins on the osteogenic differentiation of rabbit bone mesenchymal stem cells through TGF-β1 signaling pathwayAug 25, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Complement Altern Med. 2016 Aug 26 ;16(1):319. Epub 2016 Aug 26. PMID: 27561678

Article Published Date : Aug 25, 2016

Study Type : In Vitro Study

Additional Links

Substances : Panax Notoginseng

Diseases : Bone Fractures

Additional Keywords : Mesenchymal Stem Cells, Plant Extracts

[+]

Egg consumption and bone mass density among the elderly.Dec 31, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLOS Glob Public Health. 2024 ;4(5):e0002519. Epub 2024 May 2. PMID: 38696440

Article Published Date : Dec 31, 2023

Study Type : Review

Additional Links

Substances : Egg

Diseases : Bone Fractures

Pharmacological Actions : Osteoprotective

Additional Keywords : Risk Reduction

[+]

Etidronate increases bone density without reducing non-vertebral fractures.Jan 01, 2006

Click here to read the entire abstract

Pubmed Data : Cochrane Database Syst Rev. 2006(1):CD003376. Epub 2007 Jul 18. PMID: 17636719

Article Published Date : Jan 01, 2006

Study Type : Review

Additional Links

Diseases : Bone Fractures, Osteoporosis

Problem Substances : Bisphosphonates, Etidronate

[+]

Ginsenoside compound K enhances fracture healing via promoting osteogenesis and angiogenesis.Dec 31, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2022 ;13:855393. Epub 2022 Apr 1. PMID: 35462912

Article Published Date : Dec 31, 2021

Study Type : In Vitro Study

Additional Links

Substances : Ginsenosides

Diseases : Bone Fractures

Pharmacological Actions : Angiogenesis Inducing Agents

[+]

Hyperbaric oxygen may have a therapeutic effect on fracture healing and bone regeneration. Apr 14, 2011

Click here to read the entire abstract

Pubmed Data : Langenbecks Arch Surg. 2011 Apr 14. Epub 2011 Apr 14. PMID: 17653977

Article Published Date : Apr 14, 2011

Study Type : In Vitro Study

Additional Links

Diseases : Bone Fractures

Therapeutic Actions : Hyperbaric Treatment

[+]

Preclinical studies demonstrated that vitamin C has the potential to accelerate bone healing after a fracture.Sep 30, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Orthop J Sports Med. 2018 Oct ;6(10):2325967118804544. Epub 2018 Oct 25. PMID: 30386805

Article Published Date : Sep 30, 2018

Study Type : Review

Additional Links

Substances : Vitamin C

Diseases : Bone Fractures

[+]

Proton pump inhibitor use is associated with clinical spine, forearm or wrist, and total fractures.May 10, 2010

Click here to read the entire abstract

Pubmed Data : Arch Intern Med. 2010 May 10;170(9):765-71. PMID: 20458083

Article Published Date : May 10, 2010

Study Type : Review

Additional Links

Diseases : Bone Fractures, Hip Fracture, Osteoporosis

[+]

Proton pump inhibitors may result in a wide range of uncommon, though serious adverse health consequences. Sep 01, 2011

Click here to read the entire abstract

Pubmed Data : Aust Fam Physician. 2011 Sep ;40(9):705-8. PMID: 21894279

Article Published Date : Sep 01, 2011

Study Type : Review

Additional Links

Diseases : Bone Fractures, Nephritis, Pneumonia: Drug-Induced, Rebound Acid Hypersecretion Syndrome, Vitamin B 12 Deficiency, Water-Electrolyte Imbalance

Problem Substances : Proton-Pump Inhibitors

[+]

Stem cell-derived exosomes could be a promising strategy for fracture healing.Jul 24, 2017

Click here to read the entire abstract

Pubmed Data : Cell Prolif. 2017 Jul 25. Epub 2017 Jul 25. PMID: 28741758

Article Published Date : Jul 24, 2017

Study Type : Review

Additional Links

Diseases : Bone Fractures

Additional Keywords : Exosomes

[+]

Supplementation with phytonadione (Vitamin K1) and menaquinone (Vitamin K2) , particularly menaquinone-4, is associated with increased BMD and reduced fracture incidence. Oct 01, 2008

Click here to read the entire abstract

Pubmed Data : Clin Calcium. 2008 Oct;18(10):1476-82. PMID: 18830045

Article Published Date : Oct 01, 2008

Study Type : Review

Additional Links

Substances : Vitamin K, Vitamin K2, Vitamin K2: (MK-4)

Diseases : Bone Fractures, Osteoporosis

[+]

Synergistic effects of platelet-rich fibrin and photobiomodulation on bone regeneration in MC3T3-E1 Preosteoblasts.Dec 04, 2024

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Photodiagnosis Photodyn Ther. 2024 Dec 5 ;51:104436. Epub 2024 Dec 5. PMID: 39645012

Article Published Date : Dec 04, 2024

Study Type : In Vitro Study

Additional Links

Diseases : Bone Fractures

Therapeutic Actions : Infrared Light, Photobiomodulation

Additional Keywords : Bone Regeneration

[+]

The intake of natto, an excellent source of vitamin K2, may reduce bone fracture risk. Sep 01, 2009

Click here to read the entire abstract

Pubmed Data : Clin Calcium. 2009 Sep;19(9):1362-9. PMID: 19721210

Article Published Date : Sep 01, 2009

Study Type : Review

Additional Links

Substances : Natto , Vitamin K2, Vitamin K2: Menaquinone-7

Diseases : Bone Fractures

[+]

The role of low-level laser therapy in bone healing.Apr 11, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2023 Apr 12 ;24(8). Epub 2023 Apr 12. PMID: 37108257

Article Published Date : Apr 11, 2023

Study Type : Review

Additional Links

Diseases : Bone Fractures

Therapeutic Actions : Photobiomodulation

Additional Keywords : Bone Regeneration

[+]

This review examines the functional importance of vitamin C as it relates to the development and maintenance of bone tissues. Sep 10, 2015

Click here to read the entire abstract

Pubmed Data : J Bone Miner Res. 2015 Sep 11. Epub 2015 Sep 11. PMID: 26358868

Article Published Date : Sep 10, 2015

Study Type : Review

Additional Links

Substances : Vitamin C

Diseases : Bone Diseases, Bone Fractures, Osteoporosis

Additional Keywords : Epigenetic Modification, Gene Expression Regulation

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Vitamin D and calcium reduces the risk of hip and any fractures.Oct 22, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Clin Endocrinol Metab. 2021 Oct 23. Epub 2021 Oct 23. PMID: 34687206

Article Published Date : Oct 22, 2021

Study Type : Review

Additional Links

Substances : Vitamin D

Diseases : Bone Fractures

Additional Keywords : Risk Reduction

[+]

Vitamin K2 has a dual mode of action with therapeutic potential in fracture prevention and proper bone mineral density. Jan 01, 2011

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Pubmed Data : Int J Mol Med. 2011 Jan;27(1):3-14. Epub 2010 Nov 11. PMID: 21072493

Article Published Date : Jan 01, 2011

Study Type : Review

Additional Links

Substances : Vitamin K2, Vitamin K2: Menaquinone-7

Diseases : Bone Fractures, Osteoporosis

Pharmacological Actions : NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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View the Evidence: 122 Abstracts with Bone Fractures Research

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High-dose vitamin K supplementation reduces fracture incidence in postmenopausal women.Apr 01, 2009

Tai chi is effective in improving balance of older adults and in the absence of other interventions, reduces falls in the nonfrail elderly.Jan 01, 2011

This meta-analysis suggests that blood retinol level is a double-edged sword for risk of hip fracture.Aug 31, 2014

This meta-analysis suggests that whole-body vibration may prevent fractures by reducing falls.Dec 28, 2017

Vitamin D supplementation between 700 to 800 IU/d appears to reduce the risk of hip and any nonvertebral fractures in ambulatory or institutionalized elderly persons. May 11, 2005

Vitamin K1 and K2 exhibit anti-fracture activity.Dec 01, 2009

A protein-rich supplementation given to lean elderly female hip fracture patients increased the total body bone mineral density. Mar 01, 2011

Add-on yoga-based YPET accelerates fracture healing.Feb 28, 2011

Adding vitamin K(2) to vitamin D(3) with calcium reduced the lifetime probability ofat least one fracture by 25%, increased discounted survival by 0.7 quality-adjusted life-years (QALYs). Mar 08, 2012

Adjuvant treatment with aromatase inhibitors in breast cancer result in higher rates of hot flushes, musculoskeletal complaints, osteoporosis and fractures.Aug 01, 2006

Although hip bone mineral density is strongly related to hip fracture risk in elderly white women, other clinical risk factors also are independent predictors of long-term risk.Sep 01, 2004

Among adults aged 70 or more, current levothyroxine treatment was associated with a significantly increased risk of fracture, with a strong dose-response relation. Jan 01, 2011

Bisphosphonate use in early breast cancer does not appeasr to reduce the number of fractures. Jan 08, 2010

Calcium supplementation (without vitamin D) is associated with increased risk of bone fracture.Aug 01, 2008

Community water fluoridation and rate of pediatric fractures. Sep 30, 2023

Cost analysis of photobiomodulation in tibia fracture in the Brazilian public health system.Dec 31, 2022

Dietary magnesium may play a role in musculoskeletal health.Oct 29, 2017

Effectiveness of 780 nm photobiomodulation as adjunct treatment for bone exposed fractures.Apr 30, 2024

Excessive fluoride in water causes severe dental fluorosis and raises fracture risks, urging defluoridation in affected areas.Aug 31, 2024

Fracture risk is increased in patients treated with loop diuretics.Jan 01, 2006

High consumption of sugar-sweetened beverages Is associated with low bone mineral density in young people.Jan 08, 2023

Higher intake of black tea and particular classes of flavonoids were associated with lower risk of fracture related hospitalizations in elderly women at high risk of fracture.Aug 11, 2015

Higher testosterone levels in both genders and higher DHEA-S levels in women predicted a more than 60% lower risk of falling. Sep 01, 2008

Hypnosis may be capable of enhancing both anatomical and functional fracture healing.Mar 01, 1999

Lepidium sativum seeds has a marked influence on fracture healing in rabbits.Apr 30, 2007

Long-term proton pump inhibitor therapy is associated with an increased risk of hip fracture.Dec 27, 2006

Low plasma vitamin D levels are associated with osteoporotic fractures.Apr 07, 2020

Low-frequency vibratory exercise reduces the risk of bone fracture more than walking.Nov 29, 2006

Low-intensity pulse ultrasound stimulation could accelerate fracture healing of the distal radius and promote local bone formation.Oct 31, 2014

Menaquinone-7 (vitamin K2) supplementation increases osteocalcin carboxylation associated with improved bone quality.Oct 01, 2009

Most of the increase in mortality following hip and pelvic fractures is due to underlying conditions and probably would not be affected by reductions in the incidence of these fractures.Jul 22, 1996

Neuromuscular and visual impairments (as well as femoral-neck BMD) are significant and independent predictors of the risk of hip fracture in elderly women. Jul 20, 1996

Nonvertebral fracture prevention with vitamin D is dose dependent,Mar 23, 2009

one-year treatment with melatonin increased bone mineral density at femoral neck in a dose-dependent manner, while high dose melatonin increased vBMD in the spine.Jun 02, 2015

Participation in once per week tai chi classes for 16 weeks can prevent falls in relatively healthy community-dwelling older people.Aug 01, 2007

Physical activity based on dance may improve balance and hence be a useful tool in reducing the risk of falling in the elderly.Oct 01, 2005

Pulsed electromagnetic field therapy has positive significance for improving pain, body functional changes, and bone loss after vertebral fracture surgery.Dec 31, 2020

Reduction in tibial shaft fracture healing time with essential nutrient supplementation containing ascorbic acid, lysine, and proline.Dec 01, 2004

Rosiglitazone and pioglitazone increase fracture risk in women and men with type 2 diabetes.Aug 01, 2010

Soy food consumption may reduce the risk of fracture in postmenopausal women, particularly among those in the early years following menopause.Sep 12, 2005

Statin use may exacerbate muscle performance declines and falls risk associated with aging without a concomitant decrease in muscle mass.Sep 01, 2009

Statin users have poorer leaning balance which may potentially increase fall risk in this group.Oct 27, 2011

Strontium renalate is a safe and effective treatment for veterbral and hip osteoporosis.Mar 01, 2005

Subtrochanteric stress fractures in patients on oral bisphosphonate therapy is an emerging problem. Oct 01, 2011

Tai Chi decreases the number of falls, the risk for falling, and the fear of falling, and it improves functional balance and physical performance in physically inactive persons aged 70 years or older.Feb 01, 2005

The majority of those patients who will sustain a low-trauma fracture do not meet the T-score definition of osteoporosis. Conversely, younger individuals with BD in the osteoporotic range but no other risk factors have relatively low rates of fracture.Mar 01, 2012

This study found that vitamin K intake greater than the current adequate intake would be required for bone health.Dec 31, 2014

Vitamin D status appears inversely related to fractures in middle aged adults.Dec 31, 2015

Vitamin K supplementation in postmenopausal women wih osteopenia appears to protect against bone fractures and cancers. Oct 14, 2008

Vitamin K2 (MK-4) may be beneficial in the maintenance of bone health in postmenopausal women.Feb 01, 2009

vitamin Vitamin (2) works synergistically with alendronate on improving both osteocalcin carboxylation and BMD of femoral neck in postmenopausal women with osteoporosis.Jan 01, 2008

Zinc supplementation stimulates fracture healing. Sep 01, 2008

Effect of near-infrared light on in vitro cellular ATP production of osteoblasts and fibroblasts and on fracture healing.Dec 31, 2015

1,25-Dihydroxyvitamin D suppresses M1 macrophages and promotes M2 differentiation at bone injury sites.Jan 05, 2018

A mineral-rich extract from the red marine algae Lithothamnion calcareum preserves bone structure and function in female mice on a Western-style diet.Apr 01, 2010

A review of photobiomodulation therapy in bone repair.Oct 31, 2019

Accelerated bone regeneration by an astaxanthin-modified antioxidant aerogel.Sep 07, 2022

Acupuncture can increase the level of brain-derived neutrophic factor and accelerate the process of fracture healing. Apr 01, 2009

Amygdalin promotes fracture healing through TGF- β/Smad signaling in mesenchymal stem cells.Dec 31, 2019

Cannabidiol and cannabigerol, non-psychotropic cannabinoids, as analgesics that effectively manage bone fracture pain and promote healing.Aug 18, 2023

CBD leads to improvement in fracture healing and demonstrate the critical mechanical role of collagen crosslinking enzymes.Mar 18, 2015

Chaste berry positvely effects bone fracture healing in rabbits. Apr 01, 1998

Curcumin improves bone microarchitecture and enhances mineral density in transgenic mice.Jan 15, 2011

Dietary flavonoid kaempferol inhibits glucocorticoid-induced bone loss by promoting osteoblast survival.Feb 12, 2018

Dietary supplementation with conditionally essential amino acids in malnourished animals enhanced fracture and soft-tissue healing. Nov 01, 2006

Echinacoside promotes osteogenesis and angiogenesis and inhibits osteoclast formation.Mar 18, 2024

Effect of low-level laser therapy on the fracture healing process.Dec 31, 2009

Effects of concurrent use of royal jelly with hydroxyapatite on bone healing.Jun 30, 2020

Fluoroquinolones retard fracture healing in rats. Jan 01, 2005

Genistein is superior to the bone drugs alendronate, raloxifene and estradiol in osteoporotic, ovariectomized rats. Nov 01, 2008

High concentration of matrix AGEs may slow down the bone formation process in vivo.May 29, 2016

High dose vitamin D3 stimulates fracture healing.Jan 01, 1997

Bone Fractures

View the Evidence:
122 Abstracts with Bone Fractures Research