Results for Terminalia chebula

Corilagin ameliorates sleep deprivation-induced memory impairments by inhibiting NOX2 and activating Nrf2.

Article Published Date : Jun 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Phyllanthus emblica : CK(25) : AC(17), Polyphenols : CK(2736) : AC(1003), Terminalia chebula
Diseases : Memory Disorders : CK(1795) : AC(559), Sleep Disorders : CK(2031) : AC(274)
Pharmacological Actions : Antioxidants : CK(34551) : AC(14499), Neuroprotective Agents : CK(20061) : AC(7949), Nrf2 activation : CK(3156) : AC(1794)

Evaluation of medicinal herbs as a potential therapeutic option against SARS-CoV-2 targeting its main protease.

Article Published Date : Aug 03, 2020
Study Type : In Vitro Study
Additional Links
Substances : Green Tea : CK(4491) : AC(1379), Terminalia chebula
Diseases : Coronavirus Infection : CK(3250) : AC(986)
Pharmacological Actions : Antiviral Agents : CK(3095) : AC(1702)

A standardized Terminalia chebula fruit extract alters the expression of genes associated with skin architecture and barrier formation.

Article Published Date : Oct 05, 2020
Study Type : In Vitro Study
Additional Links
Substances : Terminalia chebula
Diseases : Aging Skin : CK(1444) : AC(320), Ultraviolet Radiation Induced Damage : CK(788) : AC(332)
Pharmacological Actions : Matrix Metalloproteinase-12 (MMP-12) Inhibitor : CK(21) : AC(11), Matrix metalloproteinase-1 (MMP-1) inhibitor : CK(155) : AC(92), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(944) : AC(588), Matrix metalloproteinase-3 (MMP-3) inhibitor : CK(238) : AC(107), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(1141) : AC(720), Photoprotective : CK(778) : AC(304)

Anti-obesity effect of T. chebula fruit extract on high fat diet induced obesity.

Article Published Date : Apr 30, 2021
Study Type : Animal Study
Additional Links
Substances : Terminalia chebula
Diseases : High Fat Diet : CK(2040) : AC(984), Obesity : CK(11004) : AC(2672)
Additional Keywords : Anti-Obesity Agents : CK(5172) : AC(1320)

Anti-osteoarthritic effects of an herbal composition LI73014F2 on interleukin-1β-induced primary human articular chondrocytes.

Article Published Date : Apr 26, 2020
Study Type : In Vitro Study
Additional Links
Substances : Frankincense : CK(1021) : AC(260), Terminalia chebula, Turmeric : CK(9427) : AC(3904)
Diseases : Osteoarthritis : CK(2225) : AC(627)
Pharmacological Actions : 5-Lipoxygenase Inhibitor : CK(48) : AC(31), Anti-Apoptotic : CK(5568) : AC(3160), Anti-Inflammatory Agents : CK(39737) : AC(15858), Cyclooxygenase 2 Inhibitors : CK(2264) : AC(1327), Interleukin-1 beta downregulation : CK(6063) : AC(2940), Interleukin-6 Downregulation : CK(9337) : AC(3613), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(944) : AC(588), Matrix metalloproteinase-3 (MMP-3) inhibitor : CK(238) : AC(107), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(1141) : AC(720), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(11697) : AC(4806)

Antibacterial and antioxidant effect of ethanol extracts of Terminalia chebula on Streptococcus mutans.

Article Published Date : Jun 27, 2021
Study Type : In Vitro Study
Additional Links
Substances : Terminalia chebula
Diseases : Dental Caries : CK(733) : AC(133), Steptococcus Mutans Infections : CK(484) : AC(161)
Pharmacological Actions : Anti-Bacterial Agents : CK(4228) : AC(1989), Antioxidants : CK(34551) : AC(14499)

Autophagy activation by Terminalia chebula Retz. reduce Aβ generation.

Article Published Date : Jun 05, 2022
Study Type : In Vitro Study
Additional Links
Substances : Terminalia chebula
Diseases : Alzheimer's Disease : CK(5355) : AC(2210)
Pharmacological Actions : Autophagy Up-regulation : CK(838) : AC(559), Neuroprotective Agents : CK(20061) : AC(7949)

Chebulic acid prevents hypoxia insult via Nrf2/ARE pathway in ischemic stroke.

Article Published Date : Dec 18, 2022
Study Type : In Vitro Study
Additional Links
Substances : Terminalia chebula
Diseases : Stroke: Ischemic : CK(1030) : AC(284)
Pharmacological Actions : Anti-Apoptotic : CK(5568) : AC(3160), Antioxidants : CK(34551) : AC(14499), Neuroprotective Agents : CK(20061) : AC(7949), Nrf2 activation : CK(3156) : AC(1794)

Combined Zingiber officinale and Terminalia chebula induces apoptosis and modulates mTOR and hTERT gene expressions in MCF-7 cell line.

Article Published Date : Jul 13, 2020
Study Type : In Vitro Study
Additional Links
Substances : Ginger : CK(1593) : AC(479), Terminalia chebula
Diseases : Breast Cancer : CK(8297) : AC(3043)
Pharmacological Actions : Apoptotic : CK(9585) : AC(7379)

Corilagin is a potential dual inhibitor of S and N proteins of SARS-CoV-2.

Article Published Date : Dec 27, 2022
Study Type : In Vitro Study
Additional Links
Substances : Terminalia chebula
Diseases : Coronavirus Infection : CK(3250) : AC(986)
Pharmacological Actions : Antiviral Agents : CK(3095) : AC(1702)

Curcuma longa rhizome and Boswellia serrata gum resin exerts anti-osteoarthritic effects.

Article Published Date : Nov 22, 2020
Study Type : Animal Study
Additional Links
Substances : Frankincense : CK(1021) : AC(260), Terminalia chebula
Diseases : Osteoarthritis : CK(2225) : AC(627)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39737) : AC(15858), Osteoprotective : CK(2037) : AC(685)

Effect of an aqueous extract of Terminalia chebula on endothelial dysfunction, systemic inflammation, and lipid profile in type 2 diabetes mellitus.

Article Published Date : Jul 01, 2020
Study Type : Human Study
Additional Links
Substances : Terminalia chebula
Diseases : Diabetes Mellitus: Type 2 : CK(12953) : AC(2579), Diabetic Complications : CK(4678) : AC(1606), Inflammation : CK(16094) : AC(5496)
Pharmacological Actions : Antioxidants : CK(34551) : AC(14499), Cardioprotective : CK(9504) : AC(2963), Hypolipidemic : CK(9173) : AC(2038)
Additional Keywords : Plant Extracts : CK(18762) : AC(6782)

Effects of alcoholic extract of Terminalia Chebula dried fruit on blood biochemical profile in diabetic rats.

Article Published Date : May 31, 2022
Study Type : Animal Study
Additional Links
Substances : Terminalia chebula
Diseases : Diabetes Mellitus: Type 2 : CK(12953) : AC(2579)
Pharmacological Actions : Hepatoprotective : CK(8989) : AC(3831), Hypolipidemic : CK(9173) : AC(2038), Renoprotective : CK(4544) : AC(1971)

Fruits of Terminalia chebula: A review on traditional uses, bioactive chemical constituents and pharmacological activities.

Article Published Date : Apr 19, 2020
Study Type : Review
Additional Links
Substances : Terminalia chebula
Diseases : Inflammation : CK(16094) : AC(5496), Liver Damage : CK(4109) : AC(1872), Oxidative Stress : CK(14758) : AC(5716)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39737) : AC(15858), Antioxidants : CK(34551) : AC(14499), Cytotoxic : CK(276) : AC(234), Hepatoprotective : CK(8989) : AC(3831), Neuroprotective Agents : CK(20061) : AC(7949)

Gallic acid from Terminalia chebula inhibited the growth of esophageal carcinoma cells.

Article Published Date : Oct 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid : CK(341) : AC(212), Terminalia chebula
Diseases : Esophageal Cancer : CK(912) : AC(248)
Pharmacological Actions : Apoptotic : CK(9585) : AC(7379), Bcl-2 protein down-regulation : CK(711) : AC(529)

Identification of alkaloids from Terminalia chebula as potent SARS‐ CoV‐2 main protease inhibitors.

Article Published Date : Apr 11, 2022
Study Type : In Vitro Study
Additional Links
Substances : Terminalia chebula
Diseases : Coronavirus Infection : CK(3250) : AC(986)
Pharmacological Actions : Antiviral Agents : CK(3095) : AC(1702), Protease Inhibitors : CK(19) : AC(10)

In vivo hepatoprotective activity and the underlying mechanism of chebulinic acid from Terminalia chebula fruit.

Article Published Date : Jan 22, 2021
Study Type : Animal Study
Additional Links
Substances : Terminalia chebula
Diseases : Acetaminophen (Tylenol) Toxicity : CK(902) : AC(362), Chemically-Induced Liver Damage : CK(2304) : AC(1089)
Pharmacological Actions : Hepatoprotective : CK(8989) : AC(3831)
Problem Substances : Acetaminophen

P. crispum, B. diffusa and T. chebula had the most potent antiglycation activity.

Article Published Date : Nov 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Boerhaavia diffusa : CK(10) : AC(6), Licorice : CK(1110) : AC(506), Parsley : CK(115) : AC(57), Terminalia chebula
Diseases : Advanced Glycation End products (AGE) : CK(589) : AC(249)
Pharmacological Actions : Anti-Glycation Agents : CK(351) : AC(167)

Potent anti-inflammatory Terminalia chebula fruit showed in vitro anticancer activity on lung and breast carcinoma cells.

Article Published Date : Oct 10, 2020
Study Type : In Vitro Study
Additional Links
Substances : Terminalia chebula
Diseases : Breast Cancer : CK(8297) : AC(3043), Lung Cancer : CK(3063) : AC(1429)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39737) : AC(15858)

Protective effect of Terminalia chebula Retz. extract against Aβ aggregation and Aβ-induced toxicity.

Article Published Date : Mar 24, 2021
Study Type : Animal Study
Additional Links
Substances : Terminalia chebula
Diseases : Alzheimer's Disease : CK(5355) : AC(2210)
Pharmacological Actions : Neuroprotective Agents : CK(20061) : AC(7949)

Several Herbs Found to be as Effective as Prescription Mouthwash

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Tuesday, July 8, 2014 - 10:40
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Several Herbs Found to be as Effective as Prescription Mouthwash

Why wash your mouth with chemicals, when natural, time-tested herbal remedies have been proven to work at least as well? 

According to the American Academy of Periodontology [1], "one in every two adults age 30 and older is suffering from periodontal disease, commonly referred to as gum disease." That's close to 65 million Americans according to the Centers for Disease Control and Prevention [1]. Gum diseases such as gingivitis and periodontitis can be prevented with proper daily oral hygiene.

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Terminalia chebula and Ficus racemosa controlled virulence factors produced by multiple drug resistant Pseudomonas aeruginosa.

Article Published Date : Aug 12, 2020
Study Type : In Vitro Study
Additional Links
Substances : Fig : CK(201) : AC(86), Terminalia chebula
Diseases : Infection: Antibiotic Resistant : CK(767) : AC(410), Pseudomonas aeruginosa : CK(483) : AC(365)
Pharmacological Actions : Anti-Bacterial Agents : CK(4228) : AC(1989)

Terminalia chebula fruit extract could be used as a preventative to help defend skin against damages caused by chronic exposure to environmental pollution.

Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Terminalia chebula
Diseases : Air Pollution Linked Toxicity : CK(4976) : AC(742)
Pharmacological Actions : Antioxidants : CK(34551) : AC(14499)

The analgesic effects of the Terminalia chebula extract are mediated by the suppression of brain NGF, NF-κB, and by its antioxidant activity.

Article Published Date : Oct 31, 2022
Study Type : Animal Study
Additional Links
Substances : Terminalia chebula
Diseases : Hyperalgesia : CK(339) : AC(152), Neuropathic Pain : CK(922) : AC(324), Oxidative Stress : CK(14758) : AC(5716)
Pharmacological Actions : Analgesics : CK(9680) : AC(1472), Neuritogenic : CK(224) : AC(108), NF-kappaB Inhibitor : CK(5952) : AC(3464)

The role of mTOR and oral intervention of combined Zingiber officinale-Terminalia chebula extract in type 2 diabetes models.

Article Published Date : Jun 30, 2020
Study Type : Animal Study
Additional Links
Substances : Ginger : CK(1593) : AC(479), Terminalia chebula
Diseases : Diabetes Mellitus: Type 2 : CK(12953) : AC(2579)
Pharmacological Actions : Hypoglycemic Agents : CK(9221) : AC(2076)

These data represent that T. chebula may be a valuable medicinal resource in the regulation of breast cancer proliferation, growth, and metastasis.

Article Published Date : Dec 30, 2022
Study Type : In Vitro Study
Additional Links
Substances : Terminalia chebula
Diseases : Breast Cancer : CK(8297) : AC(3043)
Pharmacological Actions : Anti-metastatic : CK(2870) : AC(2182), Antiproliferative : CK(10001) : AC(7491), Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor : CK(363) : AC(237)

This review progresses our existing knowledge to reveal the promising linkage of traditional medicine to halt Alzheimer's disease pathogenesis.

Article Published Date : Nov 08, 2018
Study Type : Review
Additional Links
Substances : Ashwagandha : CK(748) : AC(301), Asparagus : CK(55) : AC(31), Butterfly Pea : CK(80) : AC(45), Gotu Kola : CK(295) : AC(124), Terminalia chebula
Diseases : Alzheimer's Disease : CK(5355) : AC(2210)
Pharmacological Actions : Neuroprotective Agents : CK(20061) : AC(7949), Nootropic Agents : CK(30) : AC(18)

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