Results for neohesperidin

Antioxidant and pancreatic lipase inhibitory effects of flavonoids from different citrus peel extracts.

Article Published Date : Apr 10, 2020
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin : CK(438) : AC(244), Citrus Peel : CK(159) : AC(62), Hesperidin : CK(845) : AC(358), neohesperidin
Diseases : Metabolic Syndrome X : CK(3060) : AC(539), Obesity : CK(9664) : AC(2564), Oxidative Stress : CK(13443) : AC(5427)
Pharmacological Actions : Antioxidants : CK(32218) : AC(14074), Enzyme Inhibitors: Pancreatic Lipase : CK(54) : AC(25)

Citrus flavonoids as promising phytochemicals targeting diabetes and related complications.

Article Published Date : Sep 22, 2020
Study Type : Review
Additional Links
Substances : Citrus naringin : CK(438) : AC(244), Diosgenin : CK(245) : AC(146), Flavonoids : CK(4691) : AC(2170), Fruit: All : CK(9369) : AC(2225), Hesperidin : CK(845) : AC(358), Naringenin : CK(667) : AC(394), neohesperidin, Nobiletin : CK(379) : AC(226), Quercetin : CK(1864) : AC(847), Rutin : CK(460) : AC(221), Tangeretin : CK(163) : AC(93), Xanthohumol : CK(279) : AC(187)
Diseases : Diabetic Complications : CK(4283) : AC(1533)
Pharmacological Actions : Antioxidants : CK(32218) : AC(14074), Hepatoprotective : CK(8320) : AC(3743), Hypoglycemic Agents : CK(8194) : AC(2014), Hypolipidemic : CK(8317) : AC(1977), Renoprotective : CK(4133) : AC(1919)

Hesperidin promotes programmed cell death by downregulation of nongenomic estrogen receptor signalling pathway in endometrial cancer cells.

Article Published Date : Apr 13, 2018
Study Type : In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Endometrial Cancer : CK(514) : AC(125)
Pharmacological Actions : Apoptotic : CK(9052) : AC(7225)

Neohesperidin alleviates the inhibitory effect of bisphenol A on the myogenic differentiation of umbilical cord mesenchymal stem cells.

Article Published Date : Sep 14, 2024
Study Type : In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Bisphenol Toxicity : CK(4363) : AC(1306)
Problem Substances : Bisphenol A : CK(4552) : AC(1317)

Neohesperidin attenuates DSS-induced ulcerative colitis by inhibiting inflammation.

Article Published Date : Sep 17, 2024
Study Type : In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Inflammation : CK(15290) : AC(5166), Ulcerative Colitis : CK(1387) : AC(434)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(15086), Gastroprotective : CK(1651) : AC(685), NF-kappaB Inhibitor : CK(5541) : AC(3352)

Neohesperidin exerts antidepressant-like effect via the mechanistic target of rapamycin complex 1 in the medial prefrontal cortex in male mice.

Article Published Date : Sep 30, 2024
Study Type : Animal Study
Additional Links
Substances : neohesperidin
Diseases : Depression : CK(8817) : AC(1710)
Pharmacological Actions : Antidepressive Agents : CK(7300) : AC(1433)

Neohesperidin exerts lipid-regulating effects in vitro and in vivo.

Article Published Date : Dec 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Dyslipidemias : CK(1583) : AC(325)
Pharmacological Actions : Hypolipidemic : CK(8317) : AC(1977)

Neohesperidin inhibits cardiac remodeling induced by Ang II in vivo and in vitro.

Article Published Date : Jun 08, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Cardiac Hypertrophy : CK(246) : AC(134)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(15086), Antioxidants : CK(32218) : AC(14074), Cardioprotective : CK(8685) : AC(2830)

Neohesperidin inhibits TGF-β1/Smad3 signaling and alleviates bleomycin-induced pulmonary fibrosis in mice.

Article Published Date : Nov 30, 2019
Study Type : Animal Study
Additional Links
Substances : neohesperidin
Diseases : Pulmonary Fibrosis: Bleomycin-Induced : CK(171) : AC(90)
Pharmacological Actions : Anti-Fibrotic : CK(1964) : AC(1009), Chemoprotective Agents : CK(3736) : AC(1556), Transforming growth factor beta (TGF-β) inhibitor : CK(565) : AC(282)

Neohesperidin prevents Aβ25-35-induced apoptosis in primary cultured hippocampal neurons.

Article Published Date : Jun 29, 2018
Study Type : In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Alzheimer's Disease : CK(4948) : AC(2144)
Pharmacological Actions : Neuroprotective Agents : CK(17667) : AC(7599)

Neohesperidin prevents colorectal tumorigenesis by altering the gut microbiota.

Article Published Date : Jan 09, 2019
Study Type : Transgenic Animal Study
Additional Links
Substances : neohesperidin
Diseases : Colorectal Cancer : CK(4809) : AC(2231)
Pharmacological Actions : Chemopreventive : CK(6381) : AC(2133), Gastrointestinal Agents : CK(6875) : AC(2200)

Neohesperidin suppresses IgE-mediated anaphylactic reactions.

Article Published Date : Jul 31, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Allergies : CK(1712) : AC(372), Anaphylactic Reaction : CK(18) : AC(8), IgE-Mediated Hypersensitivity : CK(82) : AC(24)
Pharmacological Actions : Immunomodulatory : CK(5935) : AC(2288)

The anti-aging potential of neohesperidin and its synergistic effects with other citrus flavonoids.

Article Published Date : Nov 12, 2019
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(4691) : AC(2170), neohesperidin
Diseases : Aging : CK(5960) : AC(1429), Oxidative Stress : CK(13443) : AC(5427)
Pharmacological Actions : Antioxidants : CK(32218) : AC(14074)
Additional Keywords : Natural Substance Synergy : CK(1339) : AC(656)

The results suggest neohesperidin possesses therapeutic potential as a natural anti-catabolic treatment in osteoporosis.

Article Published Date : Jan 04, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Osteoporosis : CK(2743) : AC(738)
Pharmacological Actions : Anti-Apoptotic : CK(4942) : AC(3023), NF-kappaB Inhibitor : CK(5541) : AC(3352)
Additional Keywords : Ovariectomy-Induced Changes : CK(379) : AC(167)

Therapeutic effect of neohesperidin on TNF-α-stimulated human rheumatoid arthritis fibroblast-like synoviocytes.

Article Published Date : Sep 30, 2021
Study Type : In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Rheumatoid Arthritis : CK(2178) : AC(532)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(15086), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(10605) : AC(4622)

Therapeutic effects of citrus flavonoids neohesperidin, hesperidin and its aglycone, hesperetin on bone health.

Article Published Date : Jan 22, 2022
Study Type : Review
Additional Links
Substances : Flavonoids : CK(4691) : AC(2170), Hesperidin : CK(845) : AC(358), neohesperidin
Diseases : Osteoarthritis : CK(1971) : AC(577), Osteoporosis : CK(2743) : AC(738), Periodontitis : CK(1080) : AC(265)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(15086)

This study identified three lead compounds hesperidin, narirutin, and neohesperidin suitable for multitarget SARS-CoV-2 inhibition.

Article Published Date : Oct 27, 2022
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(4691) : AC(2170), Hesperidin : CK(845) : AC(358), neohesperidin
Diseases : Coronavirus Infection : CK(3285) : AC(983)
Pharmacological Actions : Antiviral Agents : CK(2973) : AC(1681)
Additional Keywords : SARS-CoV-2 Spike Protein

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