Results for Cytotoxicity

Ascorbate potentiates the cytotoxicity of menadione leading to an oxidative stress that kills cancer cells.

Article Published Date : Feb 29, 2004
Study Type : In Vitro Study
Additional Links
Substances : Vitamin C : CK(6028) : AC(1399)
Diseases : Liver Cancer : CK(3026) : AC(1617)
Pharmacological Actions : Antioxidants : CK(32218) : AC(14092), Chemotherapeutic : CK(3553) : AC(1487), Cytotoxicity

Cytotoxicity enhancement in MCF-7 breast cancer cells with depolymerized chitosan delivery of α-mangostin.

Article Published Date : Jul 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Xanthones : CK(84) : AC(66)
Diseases : Breast Cancer : CK(7730) : AC(2971)
Pharmacological Actions : Cytotoxicity

Cytotoxicity enhancement of α-mangostin with folate-conjugated chitosan nanoparticles in MCF-7 breast cancer cells.

Article Published Date : Nov 13, 2023
Study Type : In Vitro Study
Additional Links
Substances : Folate : CK(421) : AC(65), Xanthones : CK(84) : AC(66)
Diseases : Breast Cancer : CK(7730) : AC(2971)
Pharmacological Actions : Cytotoxicity

Flavonoids showed a dose dependent cytotoxicity towards various types of leukemia cells in vitro.

Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Apigenin : CK(432) : AC(391), Baicalein : CK(312) : AC(202), Chrysin : CK(445) : AC(274), Flavonoids : CK(4692) : AC(2171), Genistein : CK(932) : AC(431), Luteolin : CK(707) : AC(390), Naringenin : CK(667) : AC(394)
Diseases : Leukemia : CK(1997) : AC(891)
Pharmacological Actions : Antiproliferative : CK(9389) : AC(7340), Apoptotic : CK(9052) : AC(7258), Cytotoxicity
Additional Keywords : Dose Response : CK(1769) : AC(699)

kaempferol induced DNA damage and suppressed DNA repair and inhibited DNA repair associated protein expression in HL-60 cells

Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Kaempferol : CK(344) : AC(228)
Diseases : Leukemia: Acute promyelocytic leukemia : CK(72) : AC(50)
Pharmacological Actions : Antiproliferative : CK(9389) : AC(7340), Cytotoxicity, Tumor Suppressor Protein p53 Upregulation : CK(747) : AC(548)
Additional Keywords : Dose Response : CK(1769) : AC(699)

Mannosylated solid lipid nanocarriers of chrysin to target gastric cancer.

Article Published Date : Mar 18, 2021
Study Type : In Vitro Study
Additional Links
Substances : Chrysin : CK(445) : AC(274)
Diseases : Gastric Cancer : CK(1576) : AC(717)
Pharmacological Actions : Cytotoxicity

Metabolic profiling study of shikonin's cytotoxic activity in the Huh7 human hepatoma cell line.

Article Published Date : May 01, 2017
Study Type : In Vitro Study
Additional Links
Substances : Shikonin : CK(341) : AC(242)
Diseases : Liver Cancer : CK(3026) : AC(1617)
Pharmacological Actions : Cytotoxicity

Multiple myeloma tumor cells are selectively killed by pharmacologically-dosed ascorbic acid.

Article Published Date : Mar 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitamin C : CK(6028) : AC(1399)
Diseases : Multiple Myeloma : CK(404) : AC(158), Smoldering multiple myeloma (SMM) : CK(22) : AC(3)
Pharmacological Actions : Cytotoxicity
Additional Keywords : Selective Cytotoxicity : CK(269) : AC(200)

Shikonin enhances NK cells proliferation and cytotoxicity.

Article Published Date : May 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Shikonin : CK(341) : AC(242)
Diseases : Colon Cancer : CK(1898) : AC(1187)
Pharmacological Actions : Cytotoxicity, Immunomodulatory : CK(5935) : AC(2290)

Thymol elicits HCT-116 colorectal carcinoma cell death through induction of oxidative stress.

Article Published Date : Mar 26, 2017
Study Type : In Vitro Study
Additional Links
Substances : Thymol : CK(149) : AC(104)
Diseases : Colorectal Cancer : CK(4815) : AC(2235)
Pharmacological Actions : Cytotoxicity

Thymol induced Ca²⁺-dissociated cell death in prostate cancer.

Article Published Date : Jan 27, 2017
Study Type : In Vitro Study
Additional Links
Substances : Thymol : CK(149) : AC(104)
Diseases : Prostate Cancer : CK(2770) : AC(1032)
Pharmacological Actions : Cytotoxicity

Uncovering naringin's anticancer mechanisms in glioblastoma via molecular docking and network pharmacology approaches.

Article Published Date : Sep 13, 2024
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin : CK(438) : AC(244)
Diseases : Glioblastoma : CK(673) : AC(387)
Pharmacological Actions : Cytotoxicity

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