Results for Cytotoxicity

Ascorbate potentiates the cytotoxicity of menadione leading to an oxidative stress that kills cancer cells.

Article Published Date : Feb 29, 2004
Study Type : In Vitro Study
Additional Links
Substances : Vitamin C : CK(6234) : AC(1445)
Diseases : Liver Cancer : CK(3368) : AC(1800)
Pharmacological Actions : Antioxidants : CK(37827) : AC(15948), Chemotherapeutic : CK(4677) : AC(1722), Cytotoxicity

Cytotoxicity enhancement in MCF-7 breast cancer cells with depolymerized chitosan delivery of α-mangostin.

Article Published Date : Jul 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Xanthones : CK(84) : AC(66)
Diseases : Breast Cancer : CK(8606) : AC(3219)
Pharmacological Actions : Cytotoxicity

Cytotoxicity enhancement of α-mangostin with folate-conjugated chitosan nanoparticles in MCF-7 breast cancer cells.

Article Published Date : Nov 13, 2023
Study Type : In Vitro Study
Additional Links
Substances : Folate : CK(423) : AC(67), Xanthones : CK(84) : AC(66)
Diseases : Breast Cancer : CK(8606) : AC(3219)
Pharmacological Actions : Cytotoxicity

Flavonoids showed a dose dependent cytotoxicity towards various types of leukemia cells in vitro.

Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Apigenin : CK(708) : AC(413), Baicalein : CK(374) : AC(245), Chrysin : CK(511) : AC(317), Flavonoids : CK(5567) : AC(2670), Genistein : CK(951) : AC(439), Luteolin : CK(764) : AC(409), Naringenin : CK(751) : AC(414)
Diseases : Leukemia : CK(2159) : AC(962)
Pharmacological Actions : Antiproliferative : CK(11242) : AC(8420), Apoptotic : CK(10613) : AC(8204), Cytotoxicity
Additional Keywords : Dose Response : CK(1780) : AC(701)

kaempferol induced DNA damage and suppressed DNA repair and inhibited DNA repair associated protein expression in HL-60 cells

Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Kaempferol : CK(362) : AC(236)
Diseases : Leukemia: Acute promyelocytic leukemia : CK(79) : AC(54)
Pharmacological Actions : Antiproliferative : CK(11242) : AC(8420), Cytotoxicity, Tumor Suppressor Protein p53 Upregulation : CK(827) : AC(601)
Additional Keywords : Dose Response : CK(1780) : AC(701)

Mannosylated solid lipid nanocarriers of chrysin to target gastric cancer.

Article Published Date : Mar 18, 2021
Study Type : In Vitro Study
Additional Links
Substances : Chrysin : CK(511) : AC(317)
Diseases : Gastric Cancer : CK(1752) : AC(812)
Pharmacological Actions : Cytotoxicity

Metabolic profiling study of shikonin's cytotoxic activity in the Huh7 human hepatoma cell line.

Article Published Date : May 01, 2017
Study Type : In Vitro Study
Additional Links
Substances : Shikonin : CK(369) : AC(261)
Diseases : Liver Cancer : CK(3368) : AC(1800)
Pharmacological Actions : Cytotoxicity

Multiple myeloma tumor cells are selectively killed by pharmacologically-dosed ascorbic acid.

Article Published Date : Mar 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitamin C : CK(6234) : AC(1445)
Diseases : Multiple Myeloma : CK(443) : AC(169), Smoldering multiple myeloma (SMM) : CK(22) : AC(3)
Pharmacological Actions : Cytotoxicity
Additional Keywords : Selective Cytotoxicity : CK(275) : AC(202)

Polysaccharide-coated mPEG-PLA nanoparticles enhance thymoquinone delivery and therapeutic efficacy against colorectal cancer.

Article Published Date : Dec 25, 2025
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Thymoquinone : CK(1263) : AC(740)
Diseases : Colorectal Cancer : CK(5184) : AC(2460)
Pharmacological Actions : Cytotoxicity
Additional Keywords : Polysaccharides : CK(1633) : AC(905)

Shikonin enhances NK cells proliferation and cytotoxicity.

Article Published Date : May 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Shikonin : CK(369) : AC(261)
Diseases : Colon Cancer : CK(1989) : AC(1248)
Pharmacological Actions : Cytotoxicity, Immunomodulatory : CK(7128) : AC(2586)

Thymol elicits HCT-116 colorectal carcinoma cell death through induction of oxidative stress.

Article Published Date : Mar 26, 2017
Study Type : In Vitro Study
Additional Links
Substances : Thymol : CK(152) : AC(107)
Diseases : Colorectal Cancer : CK(5184) : AC(2460)
Pharmacological Actions : Cytotoxicity

Thymol induced Ca²⁺-dissociated cell death in prostate cancer.

Article Published Date : Jan 27, 2017
Study Type : In Vitro Study
Additional Links
Substances : Thymol : CK(152) : AC(107)
Diseases : Prostate Cancer : CK(2916) : AC(1104)
Pharmacological Actions : Cytotoxicity

Uncovering naringin's anticancer mechanisms in glioblastoma via molecular docking and network pharmacology approaches.

Article Published Date : Sep 13, 2024
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin : CK(465) : AC(260)
Diseases : Glioblastoma : CK(771) : AC(441)
Pharmacological Actions : Cytotoxicity

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