Results for Transgenerational inheritance

Analysis of indirect biomarkers of effect after exposure to low doses of bisphenol A in a study of successive generations of mice.

Article Published Date : Jan 25, 2022
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4416) : AC(1329)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(4570) : AC(1323)

Ancestral dichlorodiphenyltrichloroethane (DDT) exposure promotes epigenetic transgenerational inheritance of obesity.

Article Published Date : Oct 22, 2013
Study Type : Animal Study
Additional Links
Diseases : Fetal Origin of Adult Disease : CK(249) : AC(62), Obesity : CK(11004) : AC(2672), Prenatal Chemical Exposures : CK(2485) : AC(547)
Additional Keywords : Increased Risk : CK(8772) : AC(1121), Transgenerational inheritance
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT) : CK(208) : AC(35)

Ancestral folate promotes neuronal regeneration in serial generations of progeny.

Article Published Date : Jan 09, 2020
Study Type : Animal Study
Additional Links
Substances : Folate : CK(422) : AC(66)
Diseases : Folic Acid/Folate Deficiency : CK(266) : AC(40)
Pharmacological Actions : Regenerative : CK(486) : AC(201)
Additional Keywords : DNA Methylation : CK(384) : AC(78), Nerve Regeneration : CK(372) : AC(193), Transgenerational Epigenetic Modification : CK(241) : AC(91), Transgenerational inheritance

Ancestral plastics exposure induces transgenerational disease-specific sperm epigenome-wide association biomarkers.

Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4416) : AC(1329)
Additional Keywords : Risk Factors : CK(14901) : AC(2085), Transgenerational inheritance
Problem Substances : Bisphenol A : CK(4570) : AC(1323)

Atrazine has the capacity to promote the epigenetic transgenerational inheritance of disease.

Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Diseases : Pesticide Toxicity : CK(1467) : AC(478)
Additional Keywords : Transgenerational Epigenetic Modification : CK(241) : AC(91), Transgenerational inheritance
Problem Substances : Pesticides : CK(2401) : AC(488)

Benzo[a]pyrene-induces multigenerational changes in gene expression, behavior, and DNA methylation.

Article Published Date : Jun 14, 2023
Study Type : Animal Study
Additional Links
Diseases : Benzo[a]pyrene-induced Toxicity : CK(215) : AC(129)
Additional Keywords : Transgenerational inheritance
Problem Substances : Benzo(a)pyrene : CK(184) : AC(108)

Bisphenol S promotes fat storage in multiple generations.

Article Published Date : Nov 30, 2021
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4416) : AC(1329), Obesity : CK(11004) : AC(2672)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(4570) : AC(1323)
Adverse Pharmacological Actions : Obesogenic : CK(148) : AC(36)

BPA is responsible for disrupting lipid metabolic processes in the offspring through increased lipid production, abnormal transport, and disruption of lipid catabolism.

Article Published Date : Feb 21, 2023
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4416) : AC(1329)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(4570) : AC(1323)

Cannabidiol improves maternal obesity-induced behavioral, neuroinflammatory and neurochemical dysfunctions in the juvenile offspring.

Article Published Date : Apr 09, 2024
Study Type : Human Study
Additional Links
Substances : Cannabidiol : CK(3371) : AC(1007)
Diseases : Obesity : CK(11004) : AC(2672)
Pharmacological Actions : Neuroprotective Agents : CK(20061) : AC(7949)
Additional Keywords : Transgenerational inheritance

Combinational exposure to Bisphenol A and a high-fat diet causes trans-generational Malfunction of the female reproductive system.

Article Published Date : Nov 12, 2021
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4416) : AC(1329), High Fat Diet : CK(2040) : AC(984), Infertility: Female : CK(822) : AC(197)
Additional Keywords : Risk Factors : CK(14901) : AC(2085), Transgenerational inheritance
Problem Substances : Bisphenol A : CK(4570) : AC(1323)

Developmental exposure to lead induces transgenerational changes to zebrafish brain transcriptome.

Article Published Date : Dec 01, 2019
Study Type : Animal Study
Additional Links
Diseases : Prenatal Chemical Exposures : CK(2485) : AC(547)
Additional Keywords : Gene Expression : CK(286) : AC(106), Transgenerational inheritance
Problem Substances : Lead : CK(700) : AC(231)
Adverse Pharmacological Actions : Neurotoxic : CK(2966) : AC(725)

Developmental toxicity of bisphenol S in Caenorhabditis elegans and NODEF mice.

Article Published Date : Nov 30, 2021
Study Type : Animal Study
Additional Links
Diseases : Anxiety : CK(4236) : AC(758), Bisphenol Toxicity : CK(4416) : AC(1329)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol S : CK(831) : AC(271)

Dioxin induces epigenetic transgenerational inheritance of adult onset disease and sperm epimutations.

Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Diseases : Dioxin Toxicity : CK(27) : AC(11), Fetal Origin of Adult Disease : CK(249) : AC(62), Prenatal Chemical Exposures : CK(2485) : AC(547)
Additional Keywords : Risk Factors : CK(14901) : AC(2085), Transgenerational inheritance
Problem Substances : Dioxins : CK(59) : AC(18)

Embryonic exposure to aluminum chloride blocks the onset of spermatogenesis through disturbing the dynamics of testicular tight junctions.

Article Published Date : Mar 09, 2024
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity : CK(735) : AC(318), Infertility: Male : CK(1757) : AC(452), Male Reproductive Development Abnormalities : CK(91) : AC(47)
Additional Keywords : Transgenerational inheritance
Problem Substances : Aluminum : CK(1075) : AC(356)

Epigenome-wide association study for glyphosate induced transgenerational sperm DNA methylation and histone retention epigenetic biomarkers for disease.

Article Published Date : Dec 08, 2020
Study Type : Animal Study
Additional Links
Diseases : Glyphosate Toxicity : CK(801) : AC(255)
Additional Keywords : Transgenerational Epigenetic Modification : CK(241) : AC(91), Transgenerational inheritance
Problem Substances : Glyphosate : CK(1330) : AC(414)

Fish oil supplementation in fathers shows the potential to reduce metabolic and cardiovascular diseases through genetic means in offspring.

Article Published Date : Dec 07, 2023
Study Type : Animal Study
Additional Links
Substances : Fish Oil : CK(1152) : AC(187)
Diseases : Fatty Liver : CK(4309) : AC(1216), Obesity : CK(11004) : AC(2672)
Additional Keywords : Transgenerational inheritance

Gestational exposure to bisphenol S induces microvesicular steatosis in male rat offspring by modulating metaflammation.

Article Published Date : Aug 31, 2023
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4416) : AC(1329), Inflammation : CK(16094) : AC(5496)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol S : CK(831) : AC(271)

Gestational low-dose BPA exposure impacts suprachiasmatic nucleus neurogenesis and circadian activity with transgenerational effects.

Article Published Date : Apr 30, 2021
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4416) : AC(1329)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(4570) : AC(1323)

Glyphosate differentially affects the allergic immune response across generations in mice.

Article Published Date : Aug 10, 2022
Study Type : Animal Study
Additional Links
Diseases : Glyphosate Toxicity : CK(801) : AC(255)
Additional Keywords : Transgenerational inheritance
Problem Substances : Glyphosate : CK(1330) : AC(414)
Adverse Pharmacological Actions : Immunotoxic : CK(512) : AC(131)

Glyphosate herbicide: reproductive outcomes and multigenerational effects.

Article Published Date : Dec 31, 2020
Study Type : Review
Additional Links
Diseases : Glyphosate Toxicity : CK(801) : AC(255), Infertility: Female : CK(822) : AC(197)
Additional Keywords : Transgenerational inheritance
Problem Substances : Glyphosate : CK(1330) : AC(414)

Hydrocarbons (jet fuel JP-8) induce epigenetic transgenerational inheritance of obesity, reproductive disease and sperm epimutations.

Article Published Date : Mar 31, 2013
Study Type : Animal Study
Additional Links
Diseases : Hair Loss : CK(767) : AC(146), Infertility: Male : CK(1757) : AC(452), Obesity : CK(11004) : AC(2672), Polycystic Ovary Syndrome : CK(2116) : AC(332)
Additional Keywords : DNA Methylation : CK(384) : AC(78), Increased Risk : CK(8772) : AC(1121), Transgenerational inheritance
Problem Substances : Hydrocarbons : CK(52) : AC(22), Jet fuel : CK(8) : AC(4)

Influence of the maternal high-intensity-interval-training on the cardiac Sirt6 and lipid profile of the adult male offspring in rats.

Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Diseases : Cardiovascular Diseases : CK(17333) : AC(2878)
Pharmacological Actions : Insulin-Like Growth Factor Inhibition/Downregulation : CK(88) : AC(19)
Additional Keywords : Epigenetic Inheritance, Transgenerational inheritance

Learning and memory deficits produced by aspartame are heritable via the paternal lineage.

Article Published Date : Aug 30, 2023
Study Type : Animal Study
Additional Links
Diseases : Memory Disorders : CK(1795) : AC(559)
Additional Keywords : Transgenerational inheritance
Problem Substances : Aspartame : CK(317) : AC(101)

Long-term exposure to polystyrene nanoparticles causes transgenerational toxicity.

Article Published Date : Mar 31, 2022
Study Type : Animal Study
Additional Links
Diseases : Microplastic Toxicity : CK(1075) : AC(509)
Additional Keywords : Transgenerational inheritance
Problem Substances : Polystyrene nanoparticles : CK(535) : AC(269)

Low dose prenatal bisphenol A exposure on adiposity in male and female ICR offspring.

Article Published Date : May 31, 2023
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4416) : AC(1329), Obesity : CK(11004) : AC(2672), Prenatal Chemical Exposures : CK(2485) : AC(547)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(4570) : AC(1323)

Maternal exposure to environmental bisphenol A impairs the neurons in hippocampus across generations.

Article Published Date : Feb 02, 2020
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4416) : AC(1329), Prenatal Chemical Exposures : CK(2485) : AC(547)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(4570) : AC(1323)

Maternal exposure to polystyrene nanoplastics disrupts spermatogenesis in mouse offspring.

Article Published Date : Jan 20, 2025
Study Type : Animal Study
Additional Links
Diseases : Microplastic Toxicity : CK(1075) : AC(509)
Additional Keywords : Transgenerational inheritance
Problem Substances : Nano Plastic-and Micro-Particles : CK(557) : AC(257), Polystyrene nanoparticles : CK(535) : AC(269)

Maternal vitamin B12 deficiency in rats alters DNA methylation in metabolically important genes in their offspring.

Article Published Date : Apr 30, 2020
Study Type : Animal Study
Additional Links
Diseases : Vitamin B 12 Deficiency : CK(763) : AC(109)
Additional Keywords : DNA Methylation : CK(384) : AC(78), Gene Expression : CK(286) : AC(106), Transgenerational inheritance

Melatonin prevents the transgenerational toxicity of nanoplastics in zebrafish.

Article Published Date : Sep 03, 2024
Study Type : Animal Study
Additional Links
Substances : Melatonin : CK(2891) : AC(911)
Diseases : Microplastic Toxicity : CK(1075) : AC(509), Oxidative Stress : CK(14758) : AC(5716)
Additional Keywords : Transgenerational inheritance
Problem Substances : Nano Plastic-and Micro-Particles : CK(557) : AC(257)

Mercury-induced epigenetic transgenerational inheritance of abnormal neurobehavior is correlated with sperm epimutations in zebrafish.

Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Diseases : Infertility: Male : CK(1757) : AC(452)
Additional Keywords : DNA Methylation : CK(384) : AC(78), Transgenerational inheritance
Problem Substances : Mercury : CK(889) : AC(215)

Multi- and transgenerational biochemical effects of low-dose exposure to bisphenol A and 4-nonylphenol on testicular interstitial (Leydig) cells.

Article Published Date : Jan 09, 2022
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4416) : AC(1329)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(4570) : AC(1323)

Multigenerational impacts of gestational bisphenol A exposure on the sperm function and fertility of male mice.

Article Published Date : Mar 31, 2021
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4416) : AC(1329), Infertility: Male : CK(1757) : AC(452), Prenatal Chemical Exposures : CK(2485) : AC(547)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(4570) : AC(1323)

Nano-sized polystyrene plastic particles affect many cancer-related biological processes even in the next generations.

Article Published Date : Sep 09, 2022
Study Type : Animal Study
Additional Links
Diseases : Cancers: All : CK(36404) : AC(14363), Microplastic Toxicity : CK(1075) : AC(509)
Additional Keywords : Transgenerational inheritance
Problem Substances : Polystyrene nanoparticles : CK(535) : AC(269)

Nanoplastics cause transgenerational toxicity through inhibiting germline microRNA mir-38 in C. elegans.

Article Published Date : Sep 04, 2022
Study Type : Animal Study
Additional Links
Diseases : Microplastic Toxicity : CK(1075) : AC(509)
Additional Keywords : Transgenerational inheritance

Nicotinamide mononucleotide (NMN) supplementation ameliorates the impact of maternal obesity in mice.

Article Published Date : Nov 07, 2017
Study Type : Animal Study
Additional Links
Substances : Nicotinamide Mononucleotide : CK(259) : AC(109)
Diseases : Obesity : CK(11004) : AC(2672)
Additional Keywords : Anti-Obesity Agents : CK(5172) : AC(1320), Transgenerational inheritance

Paraquat exposure over generation affects lifespan and reproduction through mitochondrial disruption in C. elegans.

Article Published Date : Jan 14, 2021
Study Type : Animal Study
Additional Links
Diseases : Herbicide Toxicity : CK(68) : AC(23), Infertility : CK(2828) : AC(702)
Additional Keywords : Transgenerational inheritance
Problem Substances : Paraquat : CK(190) : AC(94)

Parental exposure to polystyrene nanoplastics and di(2-ethylhexyl) phthalate induces transgenerational growth and reproductive impairments.

Article Published Date : Jul 14, 2023
Study Type : Insect Study
Additional Links
Diseases : Infertility : CK(2828) : AC(702), Microplastic Toxicity : CK(1075) : AC(509)
Additional Keywords : Transgenerational inheritance
Problem Substances : Phthalates : CK(1705) : AC(331), Polystyrene nanoparticles : CK(535) : AC(269)

Passing experiences on to future generations: endocrine disruptors and transgenerational inheritance of epimutations in brain and sperm.

Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Additional Keywords : Transgenerational inheritance
Problem Substances : Endocrine Disruptors : CK(25) : AC(16), Polychlorinated biphenyls (PCBs) : CK(352) : AC(53)

Paternal inheritance of bisphenol A cardiotoxic effects: The implications of sperm epigenome.

Article Published Date : Feb 19, 2021
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate) : CK(1587) : AC(820)
Diseases : Bisphenol Toxicity : CK(4416) : AC(1329), Fetal Origin of Adult Disease : CK(249) : AC(62)
Pharmacological Actions : Cytoprotective : CK(809) : AC(401)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(4570) : AC(1323)
Adverse Pharmacological Actions : Cardiotoxic : CK(1220) : AC(217)

Perinatal exposure to bisphenol A impairs cognitive function via the gamma-aminobutyric acid signaling pathway in male rat offspring.

Article Published Date : Nov 04, 2023
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4416) : AC(1329), Cognitive Decline/Dysfunction : CK(5292) : AC(1050)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(4570) : AC(1323)

Polylactic acid microplastics cause transgenerational reproductive toxicity associated with activation of insulin and hedgehog ligands in C. elegans.

Article Published Date : Sep 09, 2024
Study Type : Animal Study
Additional Links
Diseases : Microplastic Toxicity : CK(1075) : AC(509)
Additional Keywords : Transgenerational inheritance
Problem Substances : Nano Plastic-and Micro-Particles : CK(557) : AC(257)

Preconceptional exposure of adult male rats to bisphenol S impairs insulin sensitivity and glucose tolerance in their male offspring.

Article Published Date : Jan 31, 2023
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4416) : AC(1329), Insulin Resistance : CK(4864) : AC(1098), Prenatal Chemical Exposures : CK(2485) : AC(547)
Additional Keywords : Transgenerational inheritance

Prenatal bisphenol S exposure induces hepatic lipid deposition in male mice offspring.

Article Published Date : Jul 04, 2023
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4416) : AC(1329), Liver Damage : CK(4109) : AC(1872), Obesity : CK(11004) : AC(2672)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol S : CK(831) : AC(271)

Prenatal exposure to a phthalate mixture leads to multigenerational and transgenerational effects on uterine morphology and function in mice.

Article Published Date : Feb 28, 2020
Study Type : Animal Study
Additional Links
Diseases : Phthalate Toxicity : CK(1232) : AC(238), Prenatal Chemical Exposures : CK(2485) : AC(547)
Additional Keywords : Transgenerational inheritance
Problem Substances : Phthalates : CK(1705) : AC(331)

Prenatal exposure to bisphenol A and/or diethylhexyl phthalate alters stress responses in rat offspring.

Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4416) : AC(1329), Phthalate Toxicity : CK(1232) : AC(238), Prenatal Chemical Exposures : CK(2485) : AC(547)
Additional Keywords : Synergistic Toxicity : CK(244) : AC(119), Transgenerational inheritance
Problem Substances : Bisphenol A : CK(4570) : AC(1323), Phthalates : CK(1705) : AC(331)

Prenatal exposure to bisphenol S and bisphenol a differentially affects male reproductive system in the adult offspring.

Article Published Date : Jul 12, 2022
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4416) : AC(1329), Infertility: Male : CK(1757) : AC(452), Prenatal Chemical Exposures : CK(2485) : AC(547)
Additional Keywords : Transgenerational inheritance
Problem Substances : Bisphenol A : CK(4570) : AC(1323)

Preterm birth is associated with epigenetic programming of transgenerational hypertension in mice.

Article Published Date : Jan 23, 2020
Study Type : Animal Study
Additional Links
Diseases : Hypertension : CK(9068) : AC(1353), Premature Birth : CK(665) : AC(73)
Additional Keywords : Risk Factors : CK(14901) : AC(2085), Transgenerational Epigenetic Modification : CK(241) : AC(91), Transgenerational inheritance

Reproductive toxicity and transgenerational effects of co-exposure to polystyrene microplastics and arsenic in zebrafish.

Article Published Date : Mar 31, 2025
Study Type : Animal Study
Additional Links
Diseases : Microplastic Toxicity : CK(1075) : AC(509)
Additional Keywords : Transgenerational inheritance
Problem Substances : Nano Plastic-and Micro-Particles : CK(557) : AC(257)

Small RNAs in the transgenerational inheritance of epigenetic information.

Article Published Date : Jan 13, 2020
Study Type : In Vitro Study
Additional Links
Additional Keywords : Epigenetic Modification : CK(566) : AC(214), Transgenerational inheritance

The data revealed that the endogenous opioid system may be altered in the offspring of morphine-treated parent.

Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Diseases : Prenatal Chemical Exposures : CK(2485) : AC(547)
Additional Keywords : Transgenerational inheritance
Problem Substances : Morphine : CK(110) : AC(40)

Connect with GreenMedInfo