Results for Liver Damage: Drug-Induced

Lycopene is a natural compound that was able to inhibit the production of ROS and mitigate the damage caused by acetaminophen.

Article Published Date : Jan 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carotenoids : CK(4371) : AC(1221), Lycopene : CK(1264) : AC(370)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(883) : AC(352), Liver Damage: Drug-Induced : CK(627) : AC(273), Oxidative Stress : CK(13443) : AC(5436)
Pharmacological Actions : Antioxidants : CK(32218) : AC(14092), Hepatoprotective : CK(8320) : AC(3749), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(931) : AC(579)
Additional Keywords : Acetaminophen (Tylenol) Toxicity, Antioxidants : CK(303) : AC(126), CAROTENOIDS, Hepatoprotective, Liver Damage: Drug-Induced, lycopene, Matrix metalloproteinase-2 (MMP-2) inhibitor, oxidative stress
Problem Substances : Acetaminophen, Paracetamol : CK(853) : AC(293)

Lycopene pretreatment improves hepatotoxicity induced by acetaminophen in mice.

Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Lycopene : CK(1264) : AC(370)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(883) : AC(352), Liver Damage: Drug-Induced : CK(627) : AC(273)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(15115), Hepatoprotective : CK(8320) : AC(3749), Interleukin-1 beta downregulation : CK(5277) : AC(2823), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(931) : AC(579)
Additional Keywords : Acetaminophen (Tylenol) Toxicity, Anti-Inflammatory Agents, Hepatoprotective, Liver Damage: Drug-Induced, lycopene
Problem Substances : Acetaminophen, Paracetamol : CK(853) : AC(293)

Protective effects of combined β-caryophyllene and silymarin against ketoprofen-induced hepatotoxicity.

Article Published Date : Jun 30, 2016
Study Type : Animal Study
Additional Links
Substances : Beta-Caryophyllene : CK(170) : AC(92), Silymarin : CK(241) : AC(110)
Diseases : Liver Damage: Drug-Induced : CK(627) : AC(273)
Pharmacological Actions : Hepatoprotective : CK(8320) : AC(3749)
Additional Keywords : Beta-Caryophyllene, Hepatoprotective, Liver Damage: Drug-Induced, Plant Extracts : CK(18030) : AC(6723), SILYMARIN
Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) : CK(3184) : AC(639)

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