Results for Liver Damage: Drug-Induced

Lycopene is a natural compound that was able to inhibit the production of ROS and mitigate the damage caused by acetaminophen.

Article Published Date : Jan 31, 2017
Study Type : Animal Study, In Vitro Study
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Substances : Carotenoids : CK(4564) : AC(1248), Lycopene : CK(1268) : AC(373)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(1446) : AC(495), Liver Damage: Drug-Induced : CK(749) : AC(334), Oxidative Stress : CK(15924) : AC(6216)
Pharmacological Actions : Antioxidants : CK(36502) : AC(15292), Hepatoprotective : CK(9537) : AC(4040), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(978) : AC(609)
Additional Keywords : Acetaminophen (Tylenol) Toxicity, Antioxidants : CK(303) : AC(126), CAROTENOIDS, Hepatoprotective, Liver Damage: Drug-Induced, lycopene, Matrix metalloproteinase-2 (MMP-2) inhibitor, oxidative stress
Problem Substances : Acetaminophen, Paracetamol : CK(1400) : AC(428)

Lycopene pretreatment improves hepatotoxicity induced by acetaminophen in mice.

Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Lycopene : CK(1268) : AC(373)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(1446) : AC(495), Liver Damage: Drug-Induced : CK(749) : AC(334)
Pharmacological Actions : Anti-Inflammatory Agents : CK(42224) : AC(16842), Hepatoprotective : CK(9537) : AC(4040), Interleukin-1 beta downregulation : CK(6446) : AC(3128), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(978) : AC(609)
Additional Keywords : Acetaminophen (Tylenol) Toxicity, Anti-Inflammatory Agents, Hepatoprotective, Liver Damage: Drug-Induced, lycopene
Problem Substances : Acetaminophen, Paracetamol : CK(1400) : AC(428)

Protective effects of combined β-caryophyllene and silymarin against ketoprofen-induced hepatotoxicity.

Article Published Date : Jun 30, 2016
Study Type : Animal Study
Additional Links
Substances : Beta-Caryophyllene : CK(172) : AC(93), Silymarin : CK(477) : AC(114)
Diseases : Liver Damage: Drug-Induced : CK(749) : AC(334)
Pharmacological Actions : Hepatoprotective : CK(9537) : AC(4040)
Additional Keywords : Beta-Caryophyllene, Hepatoprotective, Liver Damage: Drug-Induced, Plant Extracts : CK(19288) : AC(7052), SILYMARIN
Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) : CK(3243) : AC(788)

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