Results for Lipid Peroxidation

A lipid peroxidation product of DHA regulates mitochondrial homeostasis and reduces apoptosis to reduce reperfusion damage in a rat model of ischemic reperfusion.

Article Published Date : Jan 01, 2017
Study Type : Animal Study
Additional Links
Substances : DHA (Docosahexaenoic Acid) : CK(1262) : AC(241), Omega-3 Fatty Acids : CK(5649) : AC(763)
Diseases : Myocardial Infarction : CK(2061) : AC(485), Tachycardia : CK(73) : AC(14)
Pharmacological Actions : Anti-Apoptotic : CK(4942) : AC(3042), Cardioprotective : CK(8685) : AC(2875)
Additional Keywords : Cardiovascular Activity, Lipid Peroxidation, Mitochondria : CK(17) : AC(9), Omega-3 Fatty Acid Metabolism : CK(30) : AC(8)

Acute exposure to sunscreen containing titanium induces an adaptive response and oxidative stress in Mytillus galloprovincialis.

Article Published Date : Feb 28, 2018
Study Type : Animal Study
Additional Links
Diseases : Lipid Peroxidation : CK(1901) : AC(764), Oxidative Stress : CK(13443) : AC(5446)
Additional Keywords : Environmental Pollution, Lipid Peroxidation, oxidative stress, Sunscreen : CK(5) : AC(3), Titanium Dioxide
Problem Substances : Sunscreen : CK(100) : AC(21), Titanium Dioxide : CK(82) : AC(39)

Chrysin possesses restorative effect against paracetamol induced hepatotoxicity.

Article Published Date : Oct 31, 2017
Study Type : Animal Study
Additional Links
Substances : Chrysin : CK(445) : AC(274)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(883) : AC(352), Lipid Peroxidation : CK(1901) : AC(764)
Pharmacological Actions : Anti-Apoptotic : CK(4942) : AC(3042), Antioxidants : CK(32218) : AC(14107), Hepatoprotective : CK(8320) : AC(3749)
Additional Keywords : Acetaminophen (Tylenol) Toxicity, Anti-Apoptotic, Antioxidants : CK(303) : AC(126), Chrysin, Hepatoprotective, Lipid Peroxidation
Problem Substances : Acetaminophen, Paracetamol : CK(853) : AC(293)

Dandelion extracts with their antioxidant activity may be beneficial for diseases-associated with oxidative stress, and with changes of hemostasis.

Article Published Date : Jan 24, 2017
Study Type : In Vitro Study
Additional Links
Substances : Dandelion : CK(370) : AC(200)
Diseases : Hydrogen Peroxide Induced Toxicity : CK(430) : AC(343), Lipid Peroxidation : CK(1901) : AC(764), Oxidative Stress : CK(13443) : AC(5446)
Pharmacological Actions : Antioxidants : CK(32218) : AC(14107)
Additional Keywords : Antioxidants : CK(303) : AC(126), Dandelion, Hydrogen Peroxide Induced Toxicity, Lipid Peroxidation, oxidative stress, Plant Extracts : CK(18030) : AC(6724)

DHA and its lipid peroxide products exhibit anti-cancer activity through apoptotic and anti-proliferative mechanisms.

Article Published Date : May 01, 2008
Study Type : Review
Additional Links
Substances : DHA (Docosahexaenoic Acid) : CK(1262) : AC(241), Omega-3 Fatty Acids : CK(5649) : AC(763)
Diseases : Cancers
Pharmacological Actions : Antineoplastic Agents : CK(2211) : AC(1447), Antiproliferative : CK(9389) : AC(7341), Apoptotic : CK(9052) : AC(7259)
Additional Keywords : Anti-cancer, Lipid Peroxidation, Omega-3 Fatty Acid Metabolism : CK(30) : AC(8)

Fisetin exerts neuroprotection against aluminum chloride induced brain pathology.

Article Published Date : Feb 28, 2013
Study Type : Animal Study
Additional Links
Substances : Fisetin : CK(440) : AC(274)
Diseases : Aluminum Toxicity : CK(685) : AC(308), Lipid Peroxidation : CK(1901) : AC(764)
Pharmacological Actions : Antioxidants : CK(32218) : AC(14107), Neuroprotective Agents : CK(17667) : AC(7611)
Additional Keywords : aluminum toxicity, Antioxidants : CK(303) : AC(126), Fisetin, Lipid Peroxidation, Neuroprotective Agents
Problem Substances : Aluminum Chloride : CK(171) : AC(92)

Modification in the quantity, composition, and peroxidation of sebaceous lipid are believed to play a signficant role in acne pathogenesis.

Article Published Date : Jan 01, 2010
Study Type : Review
Additional Links
Diseases : Acne : CK(906) : AC(158), Inflammation : CK(15372) : AC(5212), Oxidative Stress : CK(13443) : AC(5446)
Additional Keywords : Acne Treatment, Lipid Peroxidation, natural acne remedies

Oligonol improves Aβ(25-35)-induced memory deficit and cognition impairment.

Article Published Date : Jun 30, 2014
Study Type : Animal Study
Additional Links
Substances : Lychee : CK(90) : AC(52)
Diseases : Lipid Peroxidation : CK(1901) : AC(764), Memory Disorders : CK(1555) : AC(506)
Pharmacological Actions : Antioxidants : CK(32218) : AC(14107), Neuroprotective Agents : CK(17667) : AC(7611), Nitric Oxide Inhibitor : CK(695) : AC(350)
Additional Keywords : Antioxidants : CK(303) : AC(126), Lipid Peroxidation, Lychee, Memory Disorders, Phytotherapy : CK(3908) : AC(1014), Plant Extracts : CK(18030) : AC(6724)

Oligonol is effective in protecting against DSS-induced mouse colitis and colon carcinogenesis.

Article Published Date : Jul 09, 2013
Study Type : Animal Study
Additional Links
Substances : Lychee : CK(90) : AC(52)
Diseases : Colitis : CK(1493) : AC(714), Colon Cancer : CK(1898) : AC(1187), Inflammation : CK(15372) : AC(5212), Lipid Peroxidation : CK(1901) : AC(764), Oxidative Stress : CK(13443) : AC(5446)
Pharmacological Actions : Anticarcinogenic Agents : CK(2126) : AC(1011), Antioxidants : CK(32218) : AC(14107), Cyclooxygenase 2 Inhibitors : CK(2067) : AC(1269), Interleukin-1 beta downregulation : CK(5277) : AC(2831), NF-kappaB Inhibitor : CK(5541) : AC(3365), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(10605) : AC(4639)
Additional Keywords : Colitis, COLON CANCER, Inflammation : CK(128) : AC(57), Lipid Peroxidation, Lychee, oxidative stress

Protective effect of polyphenols extract of adlay on hypercholesterolemia-induced oxidative stress.

Article Published Date : Jul 25, 2012
Study Type : Animal Study
Additional Links
Substances : Adlay : CK(128) : AC(79)
Diseases : Hypercholesterolemia : CK(2694) : AC(480), Lipid Peroxidation : CK(1901) : AC(764), Oxidative Stress : CK(13443) : AC(5446)
Pharmacological Actions : Anticholesteremic Agents : CK(4038) : AC(663), Antioxidants : CK(32218) : AC(14107), Malondialdehyde Down-regulation : CK(2826) : AC(956), Superoxide Dismutase Up-regulation : CK(2276) : AC(878)
Additional Keywords : Adlay, Anticholesteremic Agents, Antioxidants : CK(303) : AC(126), Hypercholesterolemia, Lipid Peroxidation, oxidative stress

Sucralose induces biochemical responses, including neurotoxicity, in Daphnia magna.

Article Published Date : Dec 31, 2013
Study Type : Insect Study
Additional Links
Diseases : Lipid Peroxidation : CK(1901) : AC(764)
Additional Keywords : Lipid Peroxidation, Splenda, Sucralose
Problem Substances : Sucralose (aka Splenda) : CK(109) : AC(35)
Adverse Pharmacological Actions : Neurotoxic : CK(2792) : AC(675)

Tangeretin not only enhanced cisplatin’s cytotoxic actions in Hep3B and HCT-116 human cancer cells but could protect against its harmful effects.

Article Published Date : Oct 24, 2016
Study Type : In Vitro Study
Additional Links
Substances : Tangeretin : CK(163) : AC(93)
Diseases : Chemotherapy-Induced Toxicity: Cisplatin : CK(1170) : AC(588), Inflammation : CK(15372) : AC(5212), Lipid Peroxidation : CK(1901) : AC(764), Oxidative Stress : CK(13443) : AC(5446)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(15157), Antioxidants : CK(32218) : AC(14107), Chemoprotective Agents : CK(3736) : AC(1563), Interleukin-10 upregulation : CK(1203) : AC(401), NF-kappaB Inhibitor : CK(5541) : AC(3365), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(10605) : AC(4639)
Additional Keywords : Chemotherapeutic Synergy: Cisplatin : CK(426) : AC(335), Chemotherapy-Induced Toxicity: Cisplatin, Inflammation : CK(128) : AC(57), Lipid Peroxidation, oxidative stress, Tangeretin

This in vitro study indicates that oxidation of docosahexanoic acid (DHA) into potentially damaging 4-hydroxy hexenal (HHE) exhibits less toxicity over time.

Article Published Date : Oct 05, 2018
Study Type : Human In Vitro
Additional Links
Substances : DHA (Docosahexaenoic Acid) : CK(1262) : AC(241), Omega-3 Fatty Acids : CK(5649) : AC(763)
Additional Keywords : Healthy Fats, Lipid Peroxidation

This study points out that the peroxidation products of eicosapentaenoic acid are anti-inflammatory and anti-thrombotic and, thus, cardioprotective.

Article Published Date : Jan 01, 2016
Study Type : Human Study
Additional Links
Substances : Eicosapentaenoic acid (EPA) : CK(1044) : AC(153), Omega-3 Fatty Acids : CK(5649) : AC(763)
Diseases : C-Reactive Protein : CK(3885) : AC(383), Cardiovascular Diseases : CK(17112) : AC(2823), Oxidative Stress : CK(13443) : AC(5446)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(15157), Anti-thrombotic : CK(76) : AC(34), Cardioprotective : CK(8685) : AC(2875)
Additional Keywords : Lipid Peroxidation, omega-3 fatty acids

Thymoquinone use may decrease the destructive effects of methotrexate on testicular tissue of patients using this agent.

Article Published Date : Jul 31, 2011
Study Type : Animal Study
Additional Links
Substances : Thymoquinone : CK(1178) : AC(692)
Diseases : Drug Toxicity: Methotrexate : CK(192) : AC(99), Lipid Peroxidation : CK(1901) : AC(764), Oxidative Stress : CK(13443) : AC(5446)
Pharmacological Actions : Antioxidants : CK(32218) : AC(14107)
Additional Keywords : Antioxidants : CK(303) : AC(126), Drug Toxicity: Methotrexate, Lipid Peroxidation, oxidative stress, thymoquinone

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