Results for Lipid Peroxidation

A lipid peroxidation product of DHA regulates mitochondrial homeostasis and reduces apoptosis to reduce reperfusion damage in a rat model of ischemic reperfusion.

Article Published Date : Jan 01, 2017
Study Type : Animal Study
Additional Links
Substances : DHA (Docosahexaenoic Acid) : CK(1285) : AC(244), Omega-3 Fatty Acids : CK(5655) : AC(768)
Diseases : Myocardial Infarction : CK(2128) : AC(506), Tachycardia : CK(73) : AC(14)
Pharmacological Actions : Anti-Apoptotic : CK(5539) : AC(3139), Cardioprotective : CK(9416) : AC(2947)
Additional Keywords : Cardiovascular Activity, Lipid Peroxidation, Mitochondria : CK(17) : AC(9), Omega-3 Fatty Acid Metabolism : CK(30) : AC(8)

Acute exposure to sunscreen containing titanium induces an adaptive response and oxidative stress in Mytillus galloprovincialis.

Article Published Date : Feb 28, 2018
Study Type : Animal Study
Additional Links
Diseases : Lipid Peroxidation : CK(2043) : AC(797), Oxidative Stress : CK(14617) : AC(5647)
Additional Keywords : Environmental Pollution, Lipid Peroxidation, oxidative stress, Sunscreen : CK(5) : AC(3), Titanium Dioxide
Problem Substances : Sunscreen : CK(100) : AC(21), Titanium Dioxide : CK(88) : AC(42)

Chrysin possesses restorative effect against paracetamol induced hepatotoxicity.

Article Published Date : Oct 31, 2017
Study Type : Animal Study
Additional Links
Substances : Chrysin : CK(445) : AC(274)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(896) : AC(359), Lipid Peroxidation : CK(2043) : AC(797)
Pharmacological Actions : Anti-Apoptotic : CK(5539) : AC(3139), Antioxidants : CK(34394) : AC(14418), Hepatoprotective : CK(8930) : AC(3812)
Additional Keywords : Acetaminophen (Tylenol) Toxicity, Anti-Apoptotic, Antioxidants : CK(303) : AC(126), Chrysin, Hepatoprotective, Lipid Peroxidation
Problem Substances : Acetaminophen, Paracetamol : CK(859) : AC(296)

Dandelion extracts with their antioxidant activity may be beneficial for diseases-associated with oxidative stress, and with changes of hemostasis.

Article Published Date : Jan 24, 2017
Study Type : In Vitro Study
Additional Links
Substances : Dandelion : CK(370) : AC(200)
Diseases : Hydrogen Peroxide Induced Toxicity : CK(435) : AC(347), Lipid Peroxidation : CK(2043) : AC(797), Oxidative Stress : CK(14617) : AC(5647)
Pharmacological Actions : Antioxidants : CK(34394) : AC(14418)
Additional Keywords : Antioxidants : CK(303) : AC(126), Dandelion, Hydrogen Peroxide Induced Toxicity, Lipid Peroxidation, oxidative stress, Plant Extracts : CK(18696) : AC(6766)

DHA and its lipid peroxide products exhibit anti-cancer activity through apoptotic and anti-proliferative mechanisms.

Article Published Date : May 01, 2008
Study Type : Review
Additional Links
Substances : DHA (Docosahexaenoic Acid) : CK(1285) : AC(244), Omega-3 Fatty Acids : CK(5655) : AC(768)
Diseases : Cancers
Pharmacological Actions : Antineoplastic Agents : CK(2235) : AC(1468), Antiproliferative : CK(9968) : AC(7464), Apoptotic : CK(9566) : AC(7365)
Additional Keywords : Anti-cancer, Lipid Peroxidation, Omega-3 Fatty Acid Metabolism : CK(30) : AC(8)

Fisetin exerts neuroprotection against aluminum chloride induced brain pathology.

Article Published Date : Feb 28, 2013
Study Type : Animal Study
Additional Links
Substances : Fisetin : CK(441) : AC(275)
Diseases : Aluminum Toxicity : CK(734) : AC(317), Lipid Peroxidation : CK(2043) : AC(797)
Pharmacological Actions : Antioxidants : CK(34394) : AC(14418), Neuroprotective Agents : CK(19846) : AC(7876)
Additional Keywords : aluminum toxicity, Antioxidants : CK(303) : AC(126), Fisetin, Lipid Peroxidation, Neuroprotective Agents
Problem Substances : Aluminum Chloride : CK(192) : AC(95)

Modification in the quantity, composition, and peroxidation of sebaceous lipid are believed to play a signficant role in acne pathogenesis.

Article Published Date : Jan 01, 2010
Study Type : Review
Additional Links
Diseases : Acne : CK(931) : AC(165), Inflammation : CK(15933) : AC(5437), Oxidative Stress : CK(14617) : AC(5647)
Additional Keywords : Acne Treatment, Lipid Peroxidation, natural acne remedies

Oligonol improves Aβ(25-35)-induced memory deficit and cognition impairment.

Article Published Date : Jun 30, 2014
Study Type : Animal Study
Additional Links
Substances : Lychee : CK(90) : AC(52)
Diseases : Lipid Peroxidation : CK(2043) : AC(797), Memory Disorders : CK(1595) : AC(523)
Pharmacological Actions : Antioxidants : CK(34394) : AC(14418), Neuroprotective Agents : CK(19846) : AC(7876), Nitric Oxide Inhibitor : CK(704) : AC(355)
Additional Keywords : Antioxidants : CK(303) : AC(126), Lipid Peroxidation, Lychee, Memory Disorders, Phytotherapy : CK(3981) : AC(1022), Plant Extracts : CK(18696) : AC(6766)

Oligonol is effective in protecting against DSS-induced mouse colitis and colon carcinogenesis.

Article Published Date : Jul 09, 2013
Study Type : Animal Study
Additional Links
Substances : Lychee : CK(90) : AC(52)
Diseases : Colitis : CK(1526) : AC(730), Colon Cancer : CK(1917) : AC(1201), Inflammation : CK(15933) : AC(5437), Lipid Peroxidation : CK(2043) : AC(797), Oxidative Stress : CK(14617) : AC(5647)
Pharmacological Actions : Anticarcinogenic Agents : CK(2152) : AC(1018), Antioxidants : CK(34394) : AC(14418), Cyclooxygenase 2 Inhibitors : CK(2253) : AC(1320), Interleukin-1 beta downregulation : CK(6035) : AC(2929), NF-kappaB Inhibitor : CK(5920) : AC(3445), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(11644) : AC(4783)
Additional Keywords : Colitis, COLON CANCER, Inflammation : CK(128) : AC(57), Lipid Peroxidation, Lychee, oxidative stress

Protective effect of polyphenols extract of adlay on hypercholesterolemia-induced oxidative stress.

Article Published Date : Jul 25, 2012
Study Type : Animal Study
Additional Links
Substances : Adlay : CK(128) : AC(79)
Diseases : Hypercholesterolemia : CK(2706) : AC(482), Lipid Peroxidation : CK(2043) : AC(797), Oxidative Stress : CK(14617) : AC(5647)
Pharmacological Actions : Anticholesteremic Agents : CK(4062) : AC(667), Antioxidants : CK(34394) : AC(14418), Malondialdehyde Down-regulation : CK(3023) : AC(989), Superoxide Dismutase Up-regulation : CK(2375) : AC(923)
Additional Keywords : Adlay, Anticholesteremic Agents, Antioxidants : CK(303) : AC(126), Hypercholesterolemia, Lipid Peroxidation, oxidative stress

Sucralose induces biochemical responses, including neurotoxicity, in Daphnia magna.

Article Published Date : Dec 31, 2013
Study Type : Insect Study
Additional Links
Diseases : Lipid Peroxidation : CK(2043) : AC(797)
Additional Keywords : Lipid Peroxidation, Splenda, Sucralose
Problem Substances : Sucralose (aka Splenda) : CK(109) : AC(35)
Adverse Pharmacological Actions : Neurotoxic : CK(2861) : AC(705)

Tangeretin not only enhanced cisplatin’s cytotoxic actions in Hep3B and HCT-116 human cancer cells but could protect against its harmful effects.

Article Published Date : Oct 24, 2016
Study Type : In Vitro Study
Additional Links
Substances : Tangeretin : CK(163) : AC(93)
Diseases : Chemotherapy-Induced Toxicity: Cisplatin : CK(1246) : AC(601), Inflammation : CK(15933) : AC(5437), Lipid Peroxidation : CK(2043) : AC(797), Oxidative Stress : CK(14617) : AC(5647)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39439) : AC(15739), Antioxidants : CK(34394) : AC(14418), Chemoprotective Agents : CK(4246) : AC(1618), Interleukin-10 upregulation : CK(1279) : AC(431), NF-kappaB Inhibitor : CK(5920) : AC(3445), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(11644) : AC(4783)
Additional Keywords : Chemotherapeutic Synergy: Cisplatin : CK(430) : AC(339), Chemotherapy-Induced Toxicity: Cisplatin, Inflammation : CK(128) : AC(57), Lipid Peroxidation, oxidative stress, Tangeretin

This in vitro study indicates that oxidation of docosahexanoic acid (DHA) into potentially damaging 4-hydroxy hexenal (HHE) exhibits less toxicity over time.

Article Published Date : Oct 05, 2018
Study Type : Human In Vitro
Additional Links
Substances : DHA (Docosahexaenoic Acid) : CK(1285) : AC(244), Omega-3 Fatty Acids : CK(5655) : AC(768)
Additional Keywords : Healthy Fats, Lipid Peroxidation

This study points out that the peroxidation products of eicosapentaenoic acid are anti-inflammatory and anti-thrombotic and, thus, cardioprotective.

Article Published Date : Jan 01, 2016
Study Type : Human Study
Additional Links
Substances : Eicosapentaenoic acid (EPA) : CK(1044) : AC(154), Omega-3 Fatty Acids : CK(5655) : AC(768)
Diseases : C-Reactive Protein : CK(3940) : AC(391), Cardiovascular Diseases : CK(17225) : AC(2859), Oxidative Stress : CK(14617) : AC(5647)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39439) : AC(15739), Anti-thrombotic : CK(79) : AC(34), Cardioprotective : CK(9416) : AC(2947)
Additional Keywords : Lipid Peroxidation, omega-3 fatty acids

Thymoquinone use may decrease the destructive effects of methotrexate on testicular tissue of patients using this agent.

Article Published Date : Jul 31, 2011
Study Type : Animal Study
Additional Links
Substances : Thymoquinone : CK(1178) : AC(692)
Diseases : Drug Toxicity: Methotrexate : CK(194) : AC(100), Lipid Peroxidation : CK(2043) : AC(797), Oxidative Stress : CK(14617) : AC(5647)
Pharmacological Actions : Antioxidants : CK(34394) : AC(14418)
Additional Keywords : Antioxidants : CK(303) : AC(126), Drug Toxicity: Methotrexate, Lipid Peroxidation, oxidative stress, thymoquinone

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