Results for Lipid Peroxidation

A lipid peroxidation product of DHA regulates mitochondrial homeostasis and reduces apoptosis to reduce reperfusion damage in a rat model of ischemic reperfusion.

Article Published Date : Jan 01, 2017
Study Type : Animal Study
Additional Links
Substances : DHA (Docosahexaenoic Acid) : CK(1307) : AC(246), Omega-3 Fatty Acids : CK(5797) : AC(778)
Diseases : Myocardial Infarction : CK(2213) : AC(540), Tachycardia : CK(107) : AC(20)
Pharmacological Actions : Anti-Apoptotic : CK(6196) : AC(3515), Cardioprotective : CK(9981) : AC(3155)
Additional Keywords : Cardiovascular Activity, Lipid Peroxidation, Mitochondria : CK(17) : AC(9), Omega-3 Fatty Acid Metabolism : CK(30) : AC(8)

Acute exposure to sunscreen containing titanium induces an adaptive response and oxidative stress in Mytillus galloprovincialis.

Article Published Date : Feb 28, 2018
Study Type : Animal Study
Additional Links
Diseases : Lipid Peroxidation : CK(2154) : AC(862), Oxidative Stress : CK(16297) : AC(6431)
Additional Keywords : Environmental Pollution, Lipid Peroxidation, oxidative stress, Sunscreen : CK(5) : AC(3), Titanium Dioxide
Problem Substances : Sunscreen : CK(100) : AC(21), Titanium Dioxide : CK(194) : AC(91)

Chrysin possesses restorative effect against paracetamol induced hepatotoxicity.

Article Published Date : Oct 31, 2017
Study Type : Animal Study
Additional Links
Substances : Chrysin : CK(511) : AC(317)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(1452) : AC(498), Lipid Peroxidation : CK(2154) : AC(862)
Pharmacological Actions : Anti-Apoptotic : CK(6196) : AC(3515), Antioxidants : CK(37177) : AC(15613), Hepatoprotective : CK(9703) : AC(4123)
Additional Keywords : Acetaminophen (Tylenol) Toxicity, Anti-Apoptotic, Antioxidants : CK(303) : AC(126), Chrysin, Hepatoprotective, Lipid Peroxidation
Problem Substances : Acetaminophen, Paracetamol : CK(1402) : AC(429)

Dandelion extracts with their antioxidant activity may be beneficial for diseases-associated with oxidative stress, and with changes of hemostasis.

Article Published Date : Jan 24, 2017
Study Type : In Vitro Study
Additional Links
Substances : Dandelion : CK(411) : AC(222)
Diseases : Hydrogen Peroxide Induced Toxicity : CK(451) : AC(363), Lipid Peroxidation : CK(2154) : AC(862), Oxidative Stress : CK(16297) : AC(6431)
Pharmacological Actions : Antioxidants : CK(37177) : AC(15613)
Additional Keywords : Antioxidants : CK(303) : AC(126), Dandelion, Hydrogen Peroxide Induced Toxicity, Lipid Peroxidation, oxidative stress, Plant Extracts : CK(19610) : AC(7180)

DHA and its lipid peroxide products exhibit anti-cancer activity through apoptotic and anti-proliferative mechanisms.

Article Published Date : May 01, 2008
Study Type : Review
Additional Links
Substances : DHA (Docosahexaenoic Acid) : CK(1307) : AC(246), Omega-3 Fatty Acids : CK(5797) : AC(778)
Diseases : Cancers
Pharmacological Actions : Antineoplastic Agents : CK(2461) : AC(1651), Antiproliferative : CK(10913) : AC(8190), Apoptotic : CK(10324) : AC(7997)
Additional Keywords : Anti-cancer, Lipid Peroxidation, Omega-3 Fatty Acid Metabolism : CK(30) : AC(8)

Fisetin exerts neuroprotection against aluminum chloride induced brain pathology.

Article Published Date : Feb 28, 2013
Study Type : Animal Study
Additional Links
Substances : Fisetin : CK(442) : AC(276)
Diseases : Aluminum Toxicity : CK(752) : AC(327), Lipid Peroxidation : CK(2154) : AC(862)
Pharmacological Actions : Antioxidants : CK(37177) : AC(15613), Neuroprotective Agents : CK(21615) : AC(8597)
Additional Keywords : aluminum toxicity, Antioxidants : CK(303) : AC(126), Fisetin, Lipid Peroxidation, Neuroprotective Agents
Problem Substances : Aluminum Chloride : CK(206) : AC(102)

Modification in the quantity, composition, and peroxidation of sebaceous lipid are believed to play a signficant role in acne pathogenesis.

Article Published Date : Jan 01, 2010
Study Type : Review
Additional Links
Diseases : Acne : CK(956) : AC(172), Inflammation : CK(17191) : AC(5915), Oxidative Stress : CK(16297) : AC(6431)
Additional Keywords : Acne Treatment, Lipid Peroxidation, natural acne remedies

Oligonol improves Aβ(25-35)-induced memory deficit and cognition impairment.

Article Published Date : Jun 30, 2014
Study Type : Animal Study
Additional Links
Substances : Lychee : CK(90) : AC(52)
Diseases : Lipid Peroxidation : CK(2154) : AC(862), Memory Disorders : CK(2608) : AC(684)
Pharmacological Actions : Antioxidants : CK(37177) : AC(15613), Neuroprotective Agents : CK(21615) : AC(8597), Nitric Oxide Inhibitor : CK(721) : AC(365)
Additional Keywords : Antioxidants : CK(303) : AC(126), Lipid Peroxidation, Lychee, Memory Disorders, Phytotherapy : CK(4112) : AC(1081), Plant Extracts : CK(19610) : AC(7180)

Oligonol is effective in protecting against DSS-induced mouse colitis and colon carcinogenesis.

Article Published Date : Jul 09, 2013
Study Type : Animal Study
Additional Links
Substances : Lychee : CK(90) : AC(52)
Diseases : Colitis : CK(1685) : AC(807), Colon Cancer : CK(1971) : AC(1237), Inflammation : CK(17191) : AC(5915), Lipid Peroxidation : CK(2154) : AC(862), Oxidative Stress : CK(16297) : AC(6431)
Pharmacological Actions : Anticarcinogenic Agents : CK(2161) : AC(1024), Antioxidants : CK(37177) : AC(15613), Cyclooxygenase 2 Inhibitors : CK(2372) : AC(1398), Interleukin-1 beta downregulation : CK(6694) : AC(3247), NF-kappaB Inhibitor : CK(6521) : AC(3790), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(12640) : AC(5209)
Additional Keywords : Colitis, COLON CANCER, Inflammation : CK(128) : AC(57), Lipid Peroxidation, Lychee, oxidative stress

Protective effect of polyphenols extract of adlay on hypercholesterolemia-induced oxidative stress.

Article Published Date : Jul 25, 2012
Study Type : Animal Study
Additional Links
Substances : Adlay : CK(128) : AC(79)
Diseases : Hypercholesterolemia : CK(2744) : AC(495), Lipid Peroxidation : CK(2154) : AC(862), Oxidative Stress : CK(16297) : AC(6431)
Pharmacological Actions : Anticholesteremic Agents : CK(4185) : AC(685), Antioxidants : CK(37177) : AC(15613), Malondialdehyde Down-regulation : CK(3159) : AC(1033), Superoxide Dismutase Up-regulation : CK(2594) : AC(1005)
Additional Keywords : Adlay, Anticholesteremic Agents, Antioxidants : CK(303) : AC(126), Hypercholesterolemia, Lipid Peroxidation, oxidative stress

Sucralose induces biochemical responses, including neurotoxicity, in Daphnia magna.

Article Published Date : Dec 31, 2013
Study Type : Insect Study
Additional Links
Diseases : Lipid Peroxidation : CK(2154) : AC(862)
Additional Keywords : Lipid Peroxidation, Splenda, Sucralose
Problem Substances : Sucralose (aka Splenda) : CK(109) : AC(35)
Adverse Pharmacological Actions : Neurotoxic : CK(3044) : AC(757)

Tangeretin not only enhanced cisplatin’s cytotoxic actions in Hep3B and HCT-116 human cancer cells but could protect against its harmful effects.

Article Published Date : Oct 24, 2016
Study Type : In Vitro Study
Additional Links
Substances : Tangeretin : CK(206) : AC(114)
Diseases : Chemotherapy-Induced Toxicity: Cisplatin : CK(1340) : AC(645), Inflammation : CK(17191) : AC(5915), Lipid Peroxidation : CK(2154) : AC(862), Oxidative Stress : CK(16297) : AC(6431)
Pharmacological Actions : Anti-Inflammatory Agents : CK(43311) : AC(17340), Antioxidants : CK(37177) : AC(15613), Chemoprotective Agents : CK(4562) : AC(1746), Interleukin-10 upregulation : CK(1424) : AC(484), NF-kappaB Inhibitor : CK(6521) : AC(3790), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(12640) : AC(5209)
Additional Keywords : Chemotherapeutic Synergy: Cisplatin : CK(455) : AC(361), Chemotherapy-Induced Toxicity: Cisplatin, Inflammation : CK(128) : AC(57), Lipid Peroxidation, oxidative stress, Tangeretin

This in vitro study indicates that oxidation of docosahexanoic acid (DHA) into potentially damaging 4-hydroxy hexenal (HHE) exhibits less toxicity over time.

Article Published Date : Oct 05, 2018
Study Type : Human In Vitro
Additional Links
Substances : DHA (Docosahexaenoic Acid) : CK(1307) : AC(246), Omega-3 Fatty Acids : CK(5797) : AC(778)
Additional Keywords : Healthy Fats, Lipid Peroxidation

This study points out that the peroxidation products of eicosapentaenoic acid are anti-inflammatory and anti-thrombotic and, thus, cardioprotective.

Article Published Date : Jan 01, 2016
Study Type : Human Study
Additional Links
Substances : Eicosapentaenoic acid (EPA) : CK(1044) : AC(157), Omega-3 Fatty Acids : CK(5797) : AC(778)
Diseases : C-Reactive Protein : CK(4064) : AC(404), Cardiovascular Diseases : CK(17871) : AC(3000), Oxidative Stress : CK(16297) : AC(6431)
Pharmacological Actions : Anti-Inflammatory Agents : CK(43311) : AC(17340), Anti-thrombotic : CK(80) : AC(35), Cardioprotective : CK(9981) : AC(3155)
Additional Keywords : Lipid Peroxidation, omega-3 fatty acids

Thymoquinone use may decrease the destructive effects of methotrexate on testicular tissue of patients using this agent.

Article Published Date : Jul 31, 2011
Study Type : Animal Study
Additional Links
Substances : Thymoquinone : CK(1256) : AC(736)
Diseases : Drug Toxicity: Methotrexate : CK(217) : AC(107), Lipid Peroxidation : CK(2154) : AC(862), Oxidative Stress : CK(16297) : AC(6431)
Pharmacological Actions : Antioxidants : CK(37177) : AC(15613)
Additional Keywords : Antioxidants : CK(303) : AC(126), Drug Toxicity: Methotrexate, Lipid Peroxidation, oxidative stress, thymoquinone

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