Results for Gut-liver axis

Alpha-linolenic acid ameliorates T2DM via reshaping gut-liver axis and inflammatory GPR120-NF-κB/NLRP3 pathway.

Article Published Date : Oct 31, 2025
Study Type : Animal Study
Additional Links
Diseases : Diabetes Mellitus: Type 2 : CK(13516) : AC(2692), Inflammation : CK(17215) : AC(5924), Insulin Resistance : CK(4989) : AC(1144)
Pharmacological Actions : Anti-Inflammatory Agents : CK(43406) : AC(17388), NF-kappaB Inhibitor : CK(6560) : AC(3812)
Additional Keywords : Gut-liver axis

Aluminum-induced oxidative stress promotes changes in the structure of the gut microbiota and liver deficiency.

Article Published Date : Aug 29, 2024
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity : CK(752) : AC(327), Inflammation : CK(17215) : AC(5924), Oxidative Stress : CK(16316) : AC(6440)
Additional Keywords : Gut-liver axis
Problem Substances : Aluminum : CK(1080) : AC(360)

Anti-inflammatory activities of green tea catechins along the gut-liver axis in nonalcoholic fatty liver disease.

Article Published Date : Aug 11, 2020
Study Type : Review
Additional Links
Substances : Catechin : CK(1039) : AC(335), Green Tea : CK(4545) : AC(1409)
Diseases : Lipopolysaccharide-Induced Toxicity : CK(3529) : AC(2060), Nonalcoholic fatty liver disease (NAFLD) : CK(3754) : AC(1060)
Pharmacological Actions : Anti-Inflammatory Agents : CK(43406) : AC(17388), NF-kappaB Inhibitor : CK(6560) : AC(3812)
Additional Keywords : Gut-liver axis

Anti-obesity effects of Spirulina platensis protein hydrolysate by modulating brain-liver axis in high-fat diet fed mice

Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Spirulina : CK(1155) : AC(360)
Diseases : Obesity : CK(11514) : AC(2794)
Additional Keywords : Anti-Obesity Agents : CK(5479) : AC(1390), Gut-liver axis

Arctic berry extracts target the gut-liver axis to alleviate metabolic endotoxaemia, insulin resistance and hepatic steatosis.

Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Berries: All : CK(5404) : AC(1674), Blueberry : CK(1187) : AC(348), Cloudberry : CK(16) : AC(5), Crowberry : CK(11) : AC(9), Lingonberry : CK(93) : AC(38)
Diseases : Endotoxemia : CK(384) : AC(137), Hepatic Steatosis : CK(436) : AC(181), Insulin Resistance : CK(4989) : AC(1144), Obesity : CK(11514) : AC(2794)
Pharmacological Actions : Hepatoprotective : CK(9740) : AC(4137)
Additional Keywords : Gut-liver axis, Plant Extracts : CK(19610) : AC(7189)

Astaxanthin, Haematococcus pluvialis and Haematococcus pluvialis residue alleviate liver injury in D-galactose-induced aging.

Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Substances : Astaxanthin : CK(1718) : AC(682)
Diseases : Aging : CK(6559) : AC(1613), Liver Damage : CK(4518) : AC(2058), Oxidative Stress : CK(16316) : AC(6440)
Additional Keywords : Gut-liver axis

Baicalin and the liver-gut system: Pharmacological bases explaining its therapeutic effects.

Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(5411) : AC(2584)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3754) : AC(1060)
Pharmacological Actions : Anti-Inflammatory Agents : CK(43406) : AC(17388), Gastrointestinal Agents : CK(8324) : AC(2534), NF-kappaB Inhibitor : CK(6560) : AC(3812)
Additional Keywords : Gut-liver axis

Bisphenol A exposure induces gut microbiota dysbiosis and consequent activation of gut-liver axis leading to hepatic steatosis.

Article Published Date : May 28, 2020
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4442) : AC(1344), Dysbiosis : CK(2089) : AC(609), Hepatic Steatosis : CK(436) : AC(181)
Additional Keywords : Gut-liver axis
Problem Substances : Bisphenol A : CK(4596) : AC(1338)

Bisphenol F exposure induces depression-like changes.

Article Published Date : Jan 21, 2024
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4442) : AC(1344), Depression : CK(10145) : AC(1879)
Additional Keywords : Gut-liver axis
Problem Substances : Bisphenol A : CK(4596) : AC(1338)

Blueberry attenuated liver fibrosis, protected intestinal epithelial barrier, and maintained the homeostasis of the gut microbiota.

Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Blueberry : CK(1187) : AC(348)
Diseases : Liver Fibrosis : CK(973) : AC(447)
Pharmacological Actions : Anti-Fibrotic : CK(2499) : AC(1200), Gastrointestinal Agents : CK(8324) : AC(2534), Gastroprotective : CK(1809) : AC(758), Hepatoprotective : CK(9740) : AC(4137)
Additional Keywords : Gut-liver axis

Coffee prevents fatty liver disease induced by a high-fat diet by modulating pathways of the gut-liver axis.

Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Coffee : CK(1670) : AC(210)
Diseases : High Fat Diet : CK(2149) : AC(1034), Nonalcoholic fatty liver disease (NAFLD) : CK(3754) : AC(1060)
Pharmacological Actions : Gastrointestinal Agents : CK(8324) : AC(2534), Hepatoprotective : CK(9740) : AC(4137)
Additional Keywords : Gut-liver axis

Combined nicotinamide riboside and magnesium-l-theanine protects against chronic stress-induced gut-liver injury by modulating NAD⁺ and metabolic pathways.

Article Published Date : Oct 02, 2025
Study Type : Animal Study
Additional Links
Substances : Magnesium : CK(3063) : AC(401), Vitamin B-3 (Niacin) : CK(402) : AC(72)
Diseases : Liver Damage : CK(4518) : AC(2058)
Pharmacological Actions : Hepatoprotective : CK(9740) : AC(4137)
Additional Keywords : Gut-liver axis

Continued alcohol misuse in human cirrhosis is associated with an impaired gut-liver axis.

Article Published Date : Sep 18, 2017
Study Type : Human Study
Additional Links
Diseases : Alcohol Toxicity : CK(1317) : AC(517), Cirrhosis: Liver : CK(850) : AC(220)
Additional Keywords : Gut-liver axis

Dendrobium huoshanense polysaccharide improves high-fat diet induced liver injury.

Article Published Date : Oct 31, 2023
Study Type : Animal Study
Additional Links
Substances : Orchid : CK(137) : AC(92)
Diseases : High Fat Diet : CK(2149) : AC(1034), Liver Damage : CK(4518) : AC(2058)
Pharmacological Actions : Hepatoprotective : CK(9740) : AC(4137)
Additional Keywords : Gut-liver axis, Polysaccharides : CK(1559) : AC(874)

Diallyl disulfide ameliorates ethanol-induced liver steatosis and inflammation by maintaining the fatty acid catabolism and regulating the gut-liver axis.

Article Published Date : May 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Organosulfur Compounds : CK(2174) : AC(1025)
Diseases : Alcohol Toxicity : CK(1317) : AC(517), Fatty Liver : CK(4640) : AC(1321), Inflammation : CK(17215) : AC(5924)
Pharmacological Actions : Anti-Inflammatory Agents : CK(43406) : AC(17388), Hepatoprotective : CK(9740) : AC(4137)
Additional Keywords : Gut-liver axis

Dietary approach and gut microbiota modulation for chronic hepatic encephalopathy in cirrhosis.

Article Published Date : Jun 26, 2019
Study Type : Review
Additional Links
Substances : Prebiotics : CK(441) : AC(113), Probiotics : CK(9943) : AC(1786)
Diseases : Cirrhosis : CK(826) : AC(234), Encephalopathy
Therapeutic Actions : Microbiota Transfer Therapy : CK(229) : AC(67)
Pharmacological Actions : Gastrointestinal Agents : CK(8324) : AC(2534)
Additional Keywords : Gut-liver axis, Microbiota : CK(1256) : AC(346)

Diosgenin alleviates nonalcoholic steatohepatitis through affecting liver-gut circulation.

Article Published Date : Dec 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Diosgenin : CK(245) : AC(146)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3754) : AC(1060)
Pharmacological Actions : Hepatoprotective : CK(9740) : AC(4137)
Additional Keywords : Gut-liver axis

Effects of Pu-erh and Dian Hong tea polyphenols on the gut-liver axis.

Article Published Date : Jun 01, 2023
Study Type : Animal Study
Additional Links
Substances : Black Tea : CK(1050) : AC(265)
Diseases : Gastrointestinal Complaints : CK(111) : AC(22)
Pharmacological Actions : Antioxidants : CK(37196) : AC(15625)
Additional Keywords : Gut-liver axis

Eugenol alleviated nonalcoholic fatty liver disease.

Article Published Date : Apr 30, 2022
Study Type : Animal Study
Additional Links
Substances : Eugenol : CK(223) : AC(135)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3754) : AC(1060)
Pharmacological Actions : Gastrointestinal Agents : CK(8324) : AC(2534), Hepatoprotective : CK(9740) : AC(4137), Hypolipidemic : CK(9730) : AC(2171)
Additional Keywords : Gut-brain Axis : CK(721) : AC(305), Gut-liver axis

Fecal microbiota transplantation from female donors restores gut permeability and reduces liver injury and inflammation in middle-aged male mice exposed to alcohol.

Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Diseases : Alcoholic Liver Disease : CK(666) : AC(310)
Therapeutic Actions : Microbiota Transfer Therapy : CK(229) : AC(67)
Pharmacological Actions : Hepatoprotective : CK(9740) : AC(4137)
Additional Keywords : Gut-liver axis

Fermented Angelica sinensis activates Nrf2 signaling and modulates the gut microbiota composition and metabolism to attenuate D-gal induced liver aging.

Article Published Date : Jan 02, 2023
Study Type : Animal Study
Additional Links
Substances : Angelica : CK(408) : AC(191), Fermented Foods and Beverages : CK(3488) : AC(861)
Diseases : Aging : CK(6559) : AC(1613), Liver Damage : CK(4518) : AC(2058), Oxidative Stress : CK(16316) : AC(6440)
Pharmacological Actions : Anti-Inflammatory Agents : CK(43406) : AC(17388), Antioxidants : CK(37196) : AC(15625), Gastrointestinal Agents : CK(8324) : AC(2534), Interleukin-1 beta downregulation : CK(6721) : AC(3256), Interleukin-6 Downregulation : CK(10171) : AC(3957), Nrf2 activation : CK(3438) : AC(1962), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(12694) : AC(5231)
Additional Keywords : Gut-liver axis

Fermented ginseng improved alcohol liver injury in association with changes in the gut microbiota of mice.

Article Published Date : Aug 31, 2019
Study Type : Animal Study
Additional Links
Substances : Fermented Foods and Beverages : CK(3488) : AC(861), Ginseng : CK(4221) : AC(1915)
Diseases : Alcoholic Liver Disease : CK(666) : AC(310)
Pharmacological Actions : Gastrointestinal Agents : CK(8324) : AC(2534), Hepatoprotective : CK(9740) : AC(4137)
Additional Keywords : Gut-liver axis

Folic acid ameliorates alcohol-induced liver injury via gut-liver axis homeostasis.

Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Folic Acid : CK(1332) : AC(210)
Diseases : Alcoholic Liver Disease : CK(666) : AC(310)
Pharmacological Actions : Gastrointestinal Agents : CK(8324) : AC(2534), Hepatoprotective : CK(9740) : AC(4137)
Additional Keywords : Gut-liver axis

Fu brick tea alleviates alcoholic liver injury by modulating the gut microbiota-liver axis.

Article Published Date : Sep 21, 2022
Study Type : Animal Study
Additional Links
Substances : Black Tea : CK(1050) : AC(265)
Diseases : Alcoholic Liver Disease : CK(666) : AC(310), Lipopolysaccharide-Induced Toxicity : CK(3529) : AC(2060)
Pharmacological Actions : Anti-Inflammatory Agents : CK(43406) : AC(17388), Antioxidants : CK(37196) : AC(15625), Gastrointestinal Agents : CK(8324) : AC(2534), Hepatoprotective : CK(9740) : AC(4137), NF-kappaB Inhibitor : CK(6560) : AC(3812)
Additional Keywords : Gut-liver axis

Fucoidan from Apostichopus japonicus ameliorates alcoholic liver disease by regulating gut-liver axis homeostasis.

Article Published Date : May 03, 2024
Study Type : Animal Study
Additional Links
Substances : Fucoidan : CK(867) : AC(452)
Diseases : Alcoholic Liver Disease : CK(666) : AC(310)
Pharmacological Actions : Hepatoprotective : CK(9740) : AC(4137)
Additional Keywords : Gut-liver axis

Ginsenoside Rh4 improves hepatic lipid metabolism and inflammation in a model of NAFLD.

Article Published Date : Jun 25, 2023
Study Type : Animal Study
Additional Links
Substances : Ginsenosides : CK(2649) : AC(1457)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3754) : AC(1060)
Pharmacological Actions : Hepatoprotective : CK(9740) : AC(4137), Hypolipidemic : CK(9730) : AC(2171)
Additional Keywords : Gut-liver axis

Glucopyranose from Pleurotus geesteranus prevent alcoholic liver diseases by regulating Nrf2/HO-1-TLR4/NF-κB signalling pathways and gut microbiota.

Article Published Date : Jan 19, 2022
Study Type : Animal Study
Additional Links
Substances : Medicinal Mushrooms : CK(2674) : AC(1343)
Diseases : Alcoholic Liver Disease : CK(666) : AC(310)
Pharmacological Actions : Antioxidants : CK(37196) : AC(15625), Gastrointestinal Agents : CK(8324) : AC(2534), Heme oxygenase-1 up-regulation : CK(1474) : AC(858), Nrf2 activation : CK(3438) : AC(1962)
Additional Keywords : Gut-liver axis

Gut microbiota and liver metabolomics reveal the potential mechanism of Lactobacillus rhamnosus GG modulating the liver toxicity caused by polystyrene microplastics.

Article Published Date : Dec 27, 2023
Study Type : Animal Study
Additional Links
Substances : Lactobacillus rhamnosus GG : CK(707) : AC(157)
Diseases : Chemically-Induced Liver Damage : CK(2432) : AC(1159), Microplastic Toxicity : CK(1691) : AC(767)
Pharmacological Actions : Anti-Inflammatory Agents : CK(43406) : AC(17388), Gastrointestinal Agents : CK(8324) : AC(2534), Hepatoprotective : CK(9740) : AC(4137), Interleukin-6 Downregulation : CK(10171) : AC(3957), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(12694) : AC(5231)
Additional Keywords : Gut-liver axis

Gut microbiota participates in polystyrene microplastics-induced hepatic injuries.

Article Published Date : Aug 07, 2023
Study Type : Animal Study
Additional Links
Diseases : Chemically-Induced Liver Damage : CK(2432) : AC(1159), Inflammation : CK(17215) : AC(5924), Microplastic Toxicity : CK(1691) : AC(767)
Pharmacological Actions : Gastroprotective : CK(1809) : AC(758)
Additional Keywords : Gut-liver axis
Problem Substances : Polystyrene nanoparticles : CK(703) : AC(357)

Gut-liver axis mechanisms of Hippophae rhamnoides L. in non-alcoholic fatty liver disease prevention.

Article Published Date : Nov 30, 2025
Study Type : Animal Study
Additional Links
Substances : Sea buckthorn : CK(394) : AC(166)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3754) : AC(1060)
Pharmacological Actions : Hepatoprotective : CK(9740) : AC(4137), Hypolipidemic : CK(9730) : AC(2171)
Additional Keywords : Gut-liver axis

Gut-liver axis modulation of Panax notoginseng saponins in nonalcoholic fatty liver disease.

Article Published Date : Mar 02, 2021
Study Type : Animal Study
Additional Links
Substances : Panax Notoginseng : CK(392) : AC(185)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3754) : AC(1060)
Pharmacological Actions : Hepatoprotective : CK(9740) : AC(4137)
Additional Keywords : Gut-liver axis

Hepatic toxicity induced by exposure to glyphosate/aminomethylphosphonic acid and oxytetracycline alone or in combination in zebrafish.

Article Published Date : Jan 31, 2026
Study Type : Animal Study
Additional Links
Diseases : Chemically-Induced Liver Damage : CK(2432) : AC(1159), Glyphosate Toxicity : CK(933) : AC(291)
Additional Keywords : Gut-liver axis
Problem Substances : Glyphosate : CK(1462) : AC(450)

Hepatoprotective and human gut microbiota modulation of polysaccharide-peptides in Pleurotus citrinopileatus.

Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Oyster Mushroom: Golden : CK(11) : AC(7)
Diseases : Liver Damage : CK(4518) : AC(2058)
Pharmacological Actions : Gastrointestinal Agents : CK(8324) : AC(2534), Hepatoprotective : CK(9740) : AC(4137)
Additional Keywords : Gut-liver axis, Polysaccharides : CK(1559) : AC(874)

Hepatoprotective effect of curcumin against bisphenol A-induced hepatic steatosis.

Article Published Date : Jun 29, 2022
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(8693) : AC(3798)
Diseases : Bisphenol Toxicity : CK(4442) : AC(1344), Chemically-Induced Liver Damage : CK(2432) : AC(1159)
Pharmacological Actions : Hepatoprotective : CK(9740) : AC(4137)
Additional Keywords : Gut-liver axis
Problem Substances : Bisphenol A : CK(4596) : AC(1338)

Hepatoprotective effect of probiotic Lactobacillus rhamnosus GG in a model of alcoholic liver disease.

Article Published Date : Jun 25, 2019
Study Type : Animal Study
Additional Links
Substances : Lactobacillus rhamnosus GG : CK(707) : AC(157)
Diseases : Alcoholic Liver Disease : CK(666) : AC(310)
Pharmacological Actions : Gastrointestinal Agents : CK(8324) : AC(2534), Hepatoprotective : CK(9740) : AC(4137)
Additional Keywords : Gut-liver axis

Hepatotoxicity and the role of the gut-liver axis in rats after oral administration of titanium dioxide nanoparticles.

Article Published Date : Dec 26, 2019
Study Type : Animal Study
Additional Links
Diseases : Chemically-Induced Liver Damage : CK(2432) : AC(1159), Oxidative Stress : CK(16316) : AC(6440)
Additional Keywords : Gut-liver axis
Problem Substances : Titanium Dioxide : CK(194) : AC(91)

Hericium erinaceus polysaccharides ameliorate nonalcoholic fatty liver disease.

Article Published Date : Jun 30, 2024
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus) : CK(264) : AC(138)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3754) : AC(1060)
Pharmacological Actions : Gastrointestinal Agents : CK(8324) : AC(2534)
Additional Keywords : Gut-liver axis, Polysaccharides : CK(1559) : AC(874)

Interaction between Per- and polyfluorinated substances (PFAS) and acetaminophen in disease exacerbation.

Article Published Date : Jan 02, 2024
Study Type : Review
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(1452) : AC(498), Autism Spectrum Disorders : CK(3754) : AC(585)
Additional Keywords : Gut-liver axis
Problem Substances : Acetaminophen, Paracetamol : CK(1402) : AC(429)

Intermittent fasting, especially when associated with coconut oil, had effects comparable with caloric restriction in modulating the parameters of the gut-liver axis.

Article Published Date : Jan 31, 2024
Study Type : Animal Study
Additional Links
Substances : Coconut Oil : CK(484) : AC(109)
Diseases : Obesity : CK(11514) : AC(2794)
Therapeutic Actions : Fasting/Caloric Restriction : CK(840) : AC(178)
Additional Keywords : Gut-liver axis

L. reuteri ZJ617 inhibits inflammatory and autophagy signaling pathways in gut-liver axis in piglet induced by lipopolysaccharide.

Article Published Date : Oct 12, 2021
Study Type : Animal Study
Additional Links
Substances : Lactobacillus reuteri : CK(623) : AC(127)
Diseases : Lipopolysaccharide-Induced Toxicity : CK(3529) : AC(2060)
Pharmacological Actions : Anti-Inflammatory Agents : CK(43406) : AC(17388)
Additional Keywords : Gut-liver axis

Lactobacillus fermentum CQPC06 prevents non-alcoholic fatty liver disease by stabilizing the gut-liver axis.

Article Published Date : Oct 20, 2020
Study Type : Animal Study
Additional Links
Substances : Lactobacillus fermentum : CK(228) : AC(97)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3754) : AC(1060)
Pharmacological Actions : Gastrointestinal Agents : CK(8324) : AC(2534), Hepatoprotective : CK(9740) : AC(4137)
Additional Keywords : Gut-liver axis

Lactobacillus gasseri CKCC1913 mediated modulation of the gut-liver axis alleviated insulin resistance and liver damage induced by type 2 diabetes.

Article Published Date : Sep 18, 2023
Study Type : Animal Study
Additional Links
Substances : Lactobacillus gasseri : CK(209) : AC(46)
Diseases : Diabetes Mellitus: Type 2 : CK(13516) : AC(2692), Insulin Resistance : CK(4989) : AC(1144)
Pharmacological Actions : Antioxidants : CK(37196) : AC(15625), Hepatoprotective : CK(9740) : AC(4137)
Additional Keywords : Gut-liver axis

Lactobacillus plantarum 69-2 combined with galacto-oligosaccharides alleviates d-galactose-induced aging.

Article Published Date : Mar 09, 2021
Study Type : Animal Study
Additional Links
Substances : Galacto-oligosaccharides : CK(68) : AC(10), Lactobacillus plantarum : CK(1052) : AC(335)
Diseases : Aging : CK(6559) : AC(1613)
Pharmacological Actions : Antioxidants : CK(37196) : AC(15625), Gastrointestinal Agents : CK(8324) : AC(2534), Hepatoprotective : CK(9740) : AC(4137), SIRT1 Activator : CK(408) : AC(206)
Additional Keywords : Gut-liver axis

Landscape of lipidomic metabolites in gut-liver axis of Sprague-Dawley rats after oral exposure to titanium dioxide nanoparticles.

Article Published Date : Aug 02, 2022
Study Type : Animal Study
Additional Links
Diseases : Chemically-Induced Liver Damage : CK(2432) : AC(1159), Oxidative Stress : CK(16316) : AC(6440)
Additional Keywords : Gut-liver axis
Problem Substances : Titanium Dioxide : CK(194) : AC(91)

Lupeol improves bile acid metabolism and metabolic dysfunction-associated steatotic liver disease.

Article Published Date : Jun 16, 2024
Study Type : Animal Study
Additional Links
Substances : Lupeol : CK(122) : AC(68)
Diseases : Liver Disease : CK(392) : AC(120)
Pharmacological Actions : Hepatoprotective : CK(9740) : AC(4137)
Additional Keywords : Gut-liver axis

Lycium barbarum L. polyphenols improve HFD-induced NAFLD through liver and colon metabolism and intestinal microbiota.

Article Published Date : Oct 24, 2025
Study Type : Animal Study
Additional Links
Substances : Goji : CK(610) : AC(269), Polyphenols : CK(2952) : AC(1093)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3754) : AC(1060)
Pharmacological Actions : Gastrointestinal Agents : CK(8324) : AC(2534), Hepatoprotective : CK(9740) : AC(4137)
Additional Keywords : Gut-liver axis

Lycopene attenuates western-diet-induced cognitive deficits via improving glycolipid metabolism dysfunction and inflammatory responses in gut-liver-brain axis.

Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Lycopene : CK(1268) : AC(373)
Diseases : Cognitive Decline/Dysfunction : CK(5749) : AC(1146)
Pharmacological Actions : Anti-Inflammatory Agents : CK(43406) : AC(17388)
Additional Keywords : Gut-brain Axis : CK(721) : AC(305), Gut-liver axis
Anti Therapeutic Actions : Western Diet : CK(603) : AC(152)

Melatonin improves cholestatic liver disease via the gut-liver axis.

Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Substances : Melatonin : CK(2959) : AC(926)
Diseases : Cholestasis : CK(167) : AC(55), Liver Cirrhosis : CK(974) : AC(240), Liver Disease : CK(392) : AC(120)
Pharmacological Actions : Gastrointestinal Agents : CK(8324) : AC(2534)
Additional Keywords : Gut-liver axis

microplastics and cadmium induced intestinal damage and liver inflammation in broilers.

Article Published Date : Mar 26, 2025
Study Type : Animal Study
Additional Links
Diseases : Cadmium Poisoning : CK(462) : AC(238), Microplastic Toxicity : CK(1691) : AC(767)
Additional Keywords : Gut-liver axis
Problem Substances : Cadmium : CK(628) : AC(283), Nano Plastic-and Micro-Particles : CK(1169) : AC(514)

Morinda citrifolia extract prevents alcoholic fatty liver disease by improving gut health.

Article Published Date : Nov 30, 2022
Study Type : Animal Study
Additional Links
Substances : Noni : CK(242) : AC(104)
Diseases : Alcoholic Liver Disease : CK(666) : AC(310), Inflammation : CK(17215) : AC(5924)
Pharmacological Actions : Gastrointestinal Agents : CK(8324) : AC(2534), Hepatoprotective : CK(9740) : AC(4137)
Additional Keywords : Gut-liver axis

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