Results for Gut-liver axis

A novel pectic polysaccharide from Prunella vulgaris L. and its therapeutic potential in alleviating alcoholic liver injury.

Article Published Date : Jun 06, 2026
Study Type : Animal Study
Additional Links
Substances : Prunella vulgaris : CK(237) : AC(118)
Diseases : Alcoholic Liver Disease : CK(689) : AC(321)
Pharmacological Actions : Anti-Inflammatory Agents : CK(44553) : AC(17896), Interleukin-1 beta downregulation : CK(6953) : AC(3359), Interleukin-6 Downregulation : CK(10471) : AC(4070), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(13080) : AC(5396)
Additional Keywords : Gut-liver axis, Polysaccharides : CK(1640) : AC(908)

Alpha-linolenic acid ameliorates T2DM via reshaping gut-liver axis and inflammatory GPR120-NF-κB/NLRP3 pathway.

Article Published Date : Oct 31, 2025
Study Type : Animal Study
Additional Links
Diseases : Diabetes Mellitus: Type 2 : CK(13645) : AC(2742), Inflammation : CK(17518) : AC(6064), Insulin Resistance : CK(5023) : AC(1162)
Pharmacological Actions : Anti-Inflammatory Agents : CK(44553) : AC(17896), NF-kappaB Inhibitor : CK(6759) : AC(3919)
Additional Keywords : Gut-liver axis

Aluminum-induced oxidative stress promotes changes in the structure of the gut microbiota and liver deficiency.

Article Published Date : Aug 29, 2024
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity : CK(759) : AC(331), Inflammation : CK(17518) : AC(6064), Oxidative Stress : CK(16775) : AC(6661)
Additional Keywords : Gut-liver axis
Problem Substances : Aluminum : CK(1085) : AC(362)

Anti-inflammatory activities of green tea catechins along the gut-liver axis in nonalcoholic fatty liver disease.

Article Published Date : Aug 11, 2020
Study Type : Review
Additional Links
Substances : Catechin : CK(1042) : AC(336), Green Tea : CK(4545) : AC(1414)
Diseases : Lipopolysaccharide-Induced Toxicity : CK(3605) : AC(2105), Nonalcoholic fatty liver disease (NAFLD) : CK(3808) : AC(1086)
Pharmacological Actions : Anti-Inflammatory Agents : CK(44553) : AC(17896), NF-kappaB Inhibitor : CK(6759) : AC(3919)
Additional Keywords : Gut-liver axis

Anti-obesity effects of Spirulina platensis protein hydrolysate by modulating brain-liver axis in high-fat diet fed mice

Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Spirulina : CK(1179) : AC(376)
Diseases : Obesity : CK(11723) : AC(2850)
Additional Keywords : Anti-Obesity Agents : CK(5558) : AC(1422), Gut-liver axis

Arabinoxylan from Prunella vulgaris L. by room temperature extraction and the hepatoprotective effect through gut-liver axis.

Article Published Date : May 31, 2026
Study Type : Animal Study
Additional Links
Substances : Prunella vulgaris : CK(237) : AC(118)
Diseases : Alcoholic Liver Disease : CK(689) : AC(321)
Pharmacological Actions : Gastrointestinal Agents : CK(8599) : AC(2636), Hepatoprotective : CK(9910) : AC(4220)
Additional Keywords : Gut-liver axis

Arctic berry extracts target the gut-liver axis to alleviate metabolic endotoxaemia, insulin resistance and hepatic steatosis.

Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Berries: All : CK(5404) : AC(1677), Blueberry : CK(1197) : AC(349), Cloudberry : CK(16) : AC(5), Crowberry : CK(11) : AC(9), Lingonberry : CK(93) : AC(38)
Diseases : Endotoxemia : CK(392) : AC(141), Hepatic Steatosis : CK(437) : AC(182), Insulin Resistance : CK(5023) : AC(1162), Obesity : CK(11723) : AC(2850)
Pharmacological Actions : Hepatoprotective : CK(9910) : AC(4220)
Additional Keywords : Gut-liver axis, Plant Extracts : CK(19977) : AC(7348)

Astaxanthin, Haematococcus pluvialis and Haematococcus pluvialis residue alleviate liver injury in D-galactose-induced aging.

Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Substances : Astaxanthin : CK(1721) : AC(683)
Diseases : Aging : CK(6648) : AC(1636), Liver Damage : CK(4604) : AC(2096), Oxidative Stress : CK(16775) : AC(6661)
Additional Keywords : Gut-liver axis

Baicalin and the liver-gut system: Pharmacological bases explaining its therapeutic effects.

Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(5567) : AC(2670)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3808) : AC(1086)
Pharmacological Actions : Anti-Inflammatory Agents : CK(44553) : AC(17896), Gastrointestinal Agents : CK(8599) : AC(2636), NF-kappaB Inhibitor : CK(6759) : AC(3919)
Additional Keywords : Gut-liver axis

Bisphenol A exposure induces gut microbiota dysbiosis and consequent activation of gut-liver axis leading to hepatic steatosis.

Article Published Date : May 28, 2020
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4500) : AC(1354), Dysbiosis : CK(2101) : AC(615), Hepatic Steatosis : CK(437) : AC(182)
Additional Keywords : Gut-liver axis
Problem Substances : Bisphenol A : CK(4665) : AC(1350)

Bisphenol F exposure induces depression-like changes.

Article Published Date : Jan 21, 2024
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4500) : AC(1354), Depression : CK(10779) : AC(1984)
Additional Keywords : Gut-liver axis
Problem Substances : Bisphenol A : CK(4665) : AC(1350)

Blueberry attenuated liver fibrosis, protected intestinal epithelial barrier, and maintained the homeostasis of the gut microbiota.

Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Blueberry : CK(1197) : AC(349)
Diseases : Liver Fibrosis : CK(1006) : AC(462)
Pharmacological Actions : Anti-Fibrotic : CK(2594) : AC(1234), Gastrointestinal Agents : CK(8599) : AC(2636), Gastroprotective : CK(1835) : AC(772), Hepatoprotective : CK(9910) : AC(4220)
Additional Keywords : Gut-liver axis

Bupleuri radix polysaccharides alleviate MASLD.

Article Published Date : Jan 07, 2026
Study Type : Animal Study
Additional Links
Substances : Bupleurum : CK(241) : AC(130)
Diseases : Fatty Liver : CK(4747) : AC(1357), Nonalcoholic fatty liver disease (NAFLD) : CK(3808) : AC(1086)
Pharmacological Actions : Gastroprotective : CK(1835) : AC(772), Hepatoprotective : CK(9910) : AC(4220)
Additional Keywords : Gut-liver axis

Coffee prevents fatty liver disease induced by a high-fat diet by modulating pathways of the gut-liver axis.

Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Coffee : CK(1670) : AC(210)
Diseases : High Fat Diet : CK(2187) : AC(1054), Nonalcoholic fatty liver disease (NAFLD) : CK(3808) : AC(1086)
Pharmacological Actions : Gastrointestinal Agents : CK(8599) : AC(2636), Hepatoprotective : CK(9910) : AC(4220)
Additional Keywords : Gut-liver axis

Combined nicotinamide riboside and magnesium-l-theanine protects against chronic stress-induced gut-liver injury by modulating NAD⁺ and metabolic pathways.

Article Published Date : Oct 02, 2025
Study Type : Animal Study
Additional Links
Substances : Magnesium : CK(3094) : AC(403), Vitamin B-3 (Niacin) : CK(402) : AC(72)
Diseases : Liver Damage : CK(4604) : AC(2096)
Pharmacological Actions : Hepatoprotective : CK(9910) : AC(4220)
Additional Keywords : Gut-liver axis

Continued alcohol misuse in human cirrhosis is associated with an impaired gut-liver axis.

Article Published Date : Sep 18, 2017
Study Type : Human Study
Additional Links
Diseases : Alcohol Toxicity : CK(1338) : AC(523), Cirrhosis: Liver : CK(850) : AC(224)
Additional Keywords : Gut-liver axis

Dendrobium huoshanense polysaccharide improves high-fat diet induced liver injury.

Article Published Date : Oct 31, 2023
Study Type : Animal Study
Additional Links
Substances : Orchid : CK(137) : AC(92)
Diseases : High Fat Diet : CK(2187) : AC(1054), Liver Damage : CK(4604) : AC(2096)
Pharmacological Actions : Hepatoprotective : CK(9910) : AC(4220)
Additional Keywords : Gut-liver axis, Polysaccharides : CK(1640) : AC(908)

Diallyl disulfide ameliorates ethanol-induced liver steatosis and inflammation by maintaining the fatty acid catabolism and regulating the gut-liver axis.

Article Published Date : May 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Organosulfur Compounds : CK(2174) : AC(1025)
Diseases : Alcohol Toxicity : CK(1338) : AC(523), Fatty Liver : CK(4747) : AC(1357), Inflammation : CK(17518) : AC(6064)
Pharmacological Actions : Anti-Inflammatory Agents : CK(44553) : AC(17896), Hepatoprotective : CK(9910) : AC(4220)
Additional Keywords : Gut-liver axis

Dietary approach and gut microbiota modulation for chronic hepatic encephalopathy in cirrhosis.

Article Published Date : Jun 26, 2019
Study Type : Review
Additional Links
Substances : Prebiotics : CK(444) : AC(115), Probiotics : CK(9967) : AC(1807)
Diseases : Cirrhosis : CK(826) : AC(238), Encephalopathy
Therapeutic Actions : Microbiota Transfer Therapy : CK(229) : AC(67)
Pharmacological Actions : Gastrointestinal Agents : CK(8599) : AC(2636)
Additional Keywords : Gut-liver axis, Microbiota : CK(1256) : AC(346)

Diosgenin alleviates nonalcoholic steatohepatitis through affecting liver-gut circulation.

Article Published Date : Dec 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Diosgenin : CK(250) : AC(149)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3808) : AC(1086)
Pharmacological Actions : Hepatoprotective : CK(9910) : AC(4220)
Additional Keywords : Gut-liver axis

Effects of Pu-erh and Dian Hong tea polyphenols on the gut-liver axis.

Article Published Date : Jun 01, 2023
Study Type : Animal Study
Additional Links
Substances : Black Tea : CK(1050) : AC(265)
Diseases : Gastrointestinal Complaints : CK(111) : AC(22)
Pharmacological Actions : Antioxidants : CK(37839) : AC(15955)
Additional Keywords : Gut-liver axis

Eugenol alleviated nonalcoholic fatty liver disease.

Article Published Date : Apr 30, 2022
Study Type : Animal Study
Additional Links
Substances : Eugenol : CK(226) : AC(137)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3808) : AC(1086)
Pharmacological Actions : Gastrointestinal Agents : CK(8599) : AC(2636), Hepatoprotective : CK(9910) : AC(4220), Hypolipidemic : CK(9837) : AC(2205)
Additional Keywords : Gut-brain Axis : CK(749) : AC(316), Gut-liver axis

Fecal microbiota transplantation from female donors restores gut permeability and reduces liver injury and inflammation in middle-aged male mice exposed to alcohol.

Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Diseases : Alcoholic Liver Disease : CK(689) : AC(321)
Therapeutic Actions : Microbiota Transfer Therapy : CK(229) : AC(67)
Pharmacological Actions : Hepatoprotective : CK(9910) : AC(4220)
Additional Keywords : Gut-liver axis

Fermented Angelica sinensis activates Nrf2 signaling and modulates the gut microbiota composition and metabolism to attenuate D-gal induced liver aging.

Article Published Date : Jan 02, 2023
Study Type : Animal Study
Additional Links
Substances : Angelica : CK(409) : AC(192), Fermented Foods and Beverages : CK(3500) : AC(869)
Diseases : Aging : CK(6648) : AC(1636), Liver Damage : CK(4604) : AC(2096), Oxidative Stress : CK(16775) : AC(6661)
Pharmacological Actions : Anti-Inflammatory Agents : CK(44553) : AC(17896), Antioxidants : CK(37839) : AC(15955), Gastrointestinal Agents : CK(8599) : AC(2636), Interleukin-1 beta downregulation : CK(6953) : AC(3359), Interleukin-6 Downregulation : CK(10471) : AC(4070), Nrf2 activation : CK(3537) : AC(2013), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(13080) : AC(5396)
Additional Keywords : Gut-liver axis

Fermented ginseng improved alcohol liver injury in association with changes in the gut microbiota of mice.

Article Published Date : Aug 31, 2019
Study Type : Animal Study
Additional Links
Substances : Fermented Foods and Beverages : CK(3500) : AC(869), Ginseng : CK(4221) : AC(1916)
Diseases : Alcoholic Liver Disease : CK(689) : AC(321)
Pharmacological Actions : Gastrointestinal Agents : CK(8599) : AC(2636), Hepatoprotective : CK(9910) : AC(4220)
Additional Keywords : Gut-liver axis

Folic acid ameliorates alcohol-induced liver injury via gut-liver axis homeostasis.

Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Folic Acid : CK(1332) : AC(210)
Diseases : Alcoholic Liver Disease : CK(689) : AC(321)
Pharmacological Actions : Gastrointestinal Agents : CK(8599) : AC(2636), Hepatoprotective : CK(9910) : AC(4220)
Additional Keywords : Gut-liver axis

Fu brick tea alleviates alcoholic liver injury by modulating the gut microbiota-liver axis.

Article Published Date : Sep 21, 2022
Study Type : Animal Study
Additional Links
Substances : Black Tea : CK(1050) : AC(265)
Diseases : Alcoholic Liver Disease : CK(689) : AC(321), Lipopolysaccharide-Induced Toxicity : CK(3605) : AC(2105)
Pharmacological Actions : Anti-Inflammatory Agents : CK(44553) : AC(17896), Antioxidants : CK(37839) : AC(15955), Gastrointestinal Agents : CK(8599) : AC(2636), Hepatoprotective : CK(9910) : AC(4220), NF-kappaB Inhibitor : CK(6759) : AC(3919)
Additional Keywords : Gut-liver axis

Fucoidan from Apostichopus japonicus ameliorates alcoholic liver disease by regulating gut-liver axis homeostasis.

Article Published Date : May 03, 2024
Study Type : Animal Study
Additional Links
Substances : Fucoidan : CK(888) : AC(453)
Diseases : Alcoholic Liver Disease : CK(689) : AC(321)
Pharmacological Actions : Hepatoprotective : CK(9910) : AC(4220)
Additional Keywords : Gut-liver axis

Ganoderma lucidum polysaccharides improve liver metabolic disorders by modulating gut microbiota of ovariectomized mice.

Article Published Date : Jun 30, 2026
Study Type : Animal Study
Additional Links
Substances : Reishi Mushroom : CK(759) : AC(403)
Diseases : Hyperlipidemia : CK(2283) : AC(597)
Pharmacological Actions : Gastrointestinal Agents : CK(8599) : AC(2636), Hepatoprotective : CK(9910) : AC(4220)
Additional Keywords : Gut-liver axis, Ovariectomy-Induced Changes : CK(466) : AC(206), Polysaccharides : CK(1640) : AC(908)

Ginsenoside Rh4 improves hepatic lipid metabolism and inflammation in a model of NAFLD.

Article Published Date : Jun 25, 2023
Study Type : Animal Study
Additional Links
Substances : Ginsenosides : CK(2651) : AC(1458)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3808) : AC(1086)
Pharmacological Actions : Hepatoprotective : CK(9910) : AC(4220), Hypolipidemic : CK(9837) : AC(2205)
Additional Keywords : Gut-liver axis

Glucopyranose from Pleurotus geesteranus prevent alcoholic liver diseases by regulating Nrf2/HO-1-TLR4/NF-κB signalling pathways and gut microbiota.

Article Published Date : Jan 19, 2022
Study Type : Animal Study
Additional Links
Substances : Medicinal Mushrooms : CK(2674) : AC(1413)
Diseases : Alcoholic Liver Disease : CK(689) : AC(321)
Pharmacological Actions : Antioxidants : CK(37839) : AC(15955), Gastrointestinal Agents : CK(8599) : AC(2636), Heme oxygenase-1 up-regulation : CK(1524) : AC(883), Nrf2 activation : CK(3537) : AC(2013)
Additional Keywords : Gut-liver axis

Gut microbiota and liver metabolomics reveal the potential mechanism of Lactobacillus rhamnosus GG modulating the liver toxicity caused by polystyrene microplastics.

Article Published Date : Dec 27, 2023
Study Type : Animal Study
Additional Links
Substances : Lactobacillus rhamnosus GG : CK(708) : AC(158)
Diseases : Chemically-Induced Liver Damage : CK(2461) : AC(1174), Microplastic Toxicity : CK(1718) : AC(778)
Pharmacological Actions : Anti-Inflammatory Agents : CK(44553) : AC(17896), Gastrointestinal Agents : CK(8599) : AC(2636), Hepatoprotective : CK(9910) : AC(4220), Interleukin-6 Downregulation : CK(10471) : AC(4070), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(13080) : AC(5396)
Additional Keywords : Gut-liver axis

Gut microbiota participates in polystyrene microplastics-induced hepatic injuries.

Article Published Date : Aug 07, 2023
Study Type : Animal Study
Additional Links
Diseases : Chemically-Induced Liver Damage : CK(2461) : AC(1174), Inflammation : CK(17518) : AC(6064), Microplastic Toxicity : CK(1718) : AC(778)
Pharmacological Actions : Gastroprotective : CK(1835) : AC(772)
Additional Keywords : Gut-liver axis
Problem Substances : Polystyrene nanoparticles : CK(709) : AC(361)

Gut-liver axis mechanisms of Hippophae rhamnoides L. in non-alcoholic fatty liver disease prevention.

Article Published Date : Nov 30, 2025
Study Type : Animal Study
Additional Links
Substances : Sea buckthorn : CK(394) : AC(166)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3808) : AC(1086)
Pharmacological Actions : Hepatoprotective : CK(9910) : AC(4220), Hypolipidemic : CK(9837) : AC(2205)
Additional Keywords : Gut-liver axis

Gut-liver axis modulation of Panax notoginseng saponins in nonalcoholic fatty liver disease.

Article Published Date : Mar 02, 2021
Study Type : Animal Study
Additional Links
Substances : Panax Notoginseng : CK(392) : AC(185)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3808) : AC(1086)
Pharmacological Actions : Hepatoprotective : CK(9910) : AC(4220)
Additional Keywords : Gut-liver axis

Hepatic toxicity induced by exposure to glyphosate/aminomethylphosphonic acid and oxytetracycline alone or in combination in zebrafish.

Article Published Date : Jan 31, 2026
Study Type : Animal Study
Additional Links
Diseases : Chemically-Induced Liver Damage : CK(2461) : AC(1174), Glyphosate Toxicity : CK(937) : AC(293)
Additional Keywords : Gut-liver axis
Problem Substances : Glyphosate : CK(1476) : AC(453)

Hepatoprotective and human gut microbiota modulation of polysaccharide-peptides in Pleurotus citrinopileatus.

Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Oyster Mushroom: Golden : CK(11) : AC(7)
Diseases : Liver Damage : CK(4604) : AC(2096)
Pharmacological Actions : Gastrointestinal Agents : CK(8599) : AC(2636), Hepatoprotective : CK(9910) : AC(4220)
Additional Keywords : Gut-liver axis, Polysaccharides : CK(1640) : AC(908)

Hepatoprotective effect of curcumin against bisphenol A-induced hepatic steatosis.

Article Published Date : Jun 29, 2022
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(8701) : AC(3803)
Diseases : Bisphenol Toxicity : CK(4500) : AC(1354), Chemically-Induced Liver Damage : CK(2461) : AC(1174)
Pharmacological Actions : Hepatoprotective : CK(9910) : AC(4220)
Additional Keywords : Gut-liver axis
Problem Substances : Bisphenol A : CK(4665) : AC(1350)

Hepatoprotective effect of probiotic Lactobacillus rhamnosus GG in a model of alcoholic liver disease.

Article Published Date : Jun 25, 2019
Study Type : Animal Study
Additional Links
Substances : Lactobacillus rhamnosus GG : CK(708) : AC(158)
Diseases : Alcoholic Liver Disease : CK(689) : AC(321)
Pharmacological Actions : Gastrointestinal Agents : CK(8599) : AC(2636), Hepatoprotective : CK(9910) : AC(4220)
Additional Keywords : Gut-liver axis

Hepatotoxicity and the role of the gut-liver axis in rats after oral administration of titanium dioxide nanoparticles.

Article Published Date : Dec 26, 2019
Study Type : Animal Study
Additional Links
Diseases : Chemically-Induced Liver Damage : CK(2461) : AC(1174), Oxidative Stress : CK(16775) : AC(6661)
Additional Keywords : Gut-liver axis
Problem Substances : Titanium Dioxide : CK(194) : AC(91)

Hericium erinaceus polysaccharides ameliorate nonalcoholic fatty liver disease.

Article Published Date : Jun 30, 2024
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus) : CK(264) : AC(138)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3808) : AC(1086)
Pharmacological Actions : Gastrointestinal Agents : CK(8599) : AC(2636)
Additional Keywords : Gut-liver axis, Polysaccharides : CK(1640) : AC(908)

Interaction between Per- and polyfluorinated substances (PFAS) and acetaminophen in disease exacerbation.

Article Published Date : Jan 02, 2024
Study Type : Review
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity : CK(1464) : AC(504), Autism Spectrum Disorders : CK(3761) : AC(589)
Additional Keywords : Gut-liver axis
Problem Substances : Acetaminophen, Paracetamol : CK(1414) : AC(435)

Intermittent fasting, especially when associated with coconut oil, had effects comparable with caloric restriction in modulating the parameters of the gut-liver axis.

Article Published Date : Jan 31, 2024
Study Type : Animal Study
Additional Links
Substances : Coconut Oil : CK(567) : AC(118)
Diseases : Obesity : CK(11723) : AC(2850)
Therapeutic Actions : Fasting/Caloric Restriction : CK(840) : AC(178)
Additional Keywords : Gut-liver axis

L. reuteri ZJ617 inhibits inflammatory and autophagy signaling pathways in gut-liver axis in piglet induced by lipopolysaccharide.

Article Published Date : Oct 12, 2021
Study Type : Animal Study
Additional Links
Substances : Lactobacillus reuteri : CK(623) : AC(127)
Diseases : Lipopolysaccharide-Induced Toxicity : CK(3605) : AC(2105)
Pharmacological Actions : Anti-Inflammatory Agents : CK(44553) : AC(17896)
Additional Keywords : Gut-liver axis

Lactobacillus fermentum CQPC06 prevents non-alcoholic fatty liver disease by stabilizing the gut-liver axis.

Article Published Date : Oct 20, 2020
Study Type : Animal Study
Additional Links
Substances : Lactobacillus fermentum : CK(228) : AC(97)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3808) : AC(1086)
Pharmacological Actions : Gastrointestinal Agents : CK(8599) : AC(2636), Hepatoprotective : CK(9910) : AC(4220)
Additional Keywords : Gut-liver axis

Lactobacillus gasseri CKCC1913 mediated modulation of the gut-liver axis alleviated insulin resistance and liver damage induced by type 2 diabetes.

Article Published Date : Sep 18, 2023
Study Type : Animal Study
Additional Links
Substances : Lactobacillus gasseri : CK(209) : AC(46)
Diseases : Diabetes Mellitus: Type 2 : CK(13645) : AC(2742), Insulin Resistance : CK(5023) : AC(1162)
Pharmacological Actions : Antioxidants : CK(37839) : AC(15955), Hepatoprotective : CK(9910) : AC(4220)
Additional Keywords : Gut-liver axis

Lactobacillus plantarum 69-2 combined with galacto-oligosaccharides alleviates d-galactose-induced aging.

Article Published Date : Mar 09, 2021
Study Type : Animal Study
Additional Links
Substances : Galacto-oligosaccharides : CK(68) : AC(10), Lactobacillus plantarum : CK(1065) : AC(338)
Diseases : Aging : CK(6648) : AC(1636)
Pharmacological Actions : Antioxidants : CK(37839) : AC(15955), Gastrointestinal Agents : CK(8599) : AC(2636), Hepatoprotective : CK(9910) : AC(4220), SIRT1 Activator : CK(420) : AC(212)
Additional Keywords : Gut-liver axis

Landscape of lipidomic metabolites in gut-liver axis of Sprague-Dawley rats after oral exposure to titanium dioxide nanoparticles.

Article Published Date : Aug 02, 2022
Study Type : Animal Study
Additional Links
Diseases : Chemically-Induced Liver Damage : CK(2461) : AC(1174), Oxidative Stress : CK(16775) : AC(6661)
Additional Keywords : Gut-liver axis
Problem Substances : Titanium Dioxide : CK(194) : AC(91)

Lupeol improves bile acid metabolism and metabolic dysfunction-associated steatotic liver disease.

Article Published Date : Jun 16, 2024
Study Type : Animal Study
Additional Links
Substances : Lupeol : CK(122) : AC(68)
Diseases : Liver Disease : CK(394) : AC(121)
Pharmacological Actions : Hepatoprotective : CK(9910) : AC(4220)
Additional Keywords : Gut-liver axis

Lycium barbarum L. polyphenols improve HFD-induced NAFLD through liver and colon metabolism and intestinal microbiota.

Article Published Date : Oct 24, 2025
Study Type : Animal Study
Additional Links
Substances : Goji : CK(610) : AC(269), Polyphenols : CK(2961) : AC(1098)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3808) : AC(1086)
Pharmacological Actions : Gastrointestinal Agents : CK(8599) : AC(2636), Hepatoprotective : CK(9910) : AC(4220)
Additional Keywords : Gut-liver axis

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