Results for Gut-liver axis

Aluminum-induced oxidative stress promotes changes in the structure of the gut microbiota and liver deficiency.

Article Published Date : Aug 29, 2024
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity : CK(685) : AC(308), Inflammation : CK(15339) : AC(5190), Oxidative Stress : CK(13443) : AC(5439)
Additional Keywords : Gut-liver axis
Problem Substances : Aluminum : CK(1060) : AC(348)

Anti-inflammatory activities of green tea catechins along the gut-liver axis in nonalcoholic fatty liver disease.

Article Published Date : Aug 11, 2020
Study Type : Review
Additional Links
Substances : Catechin : CK(965) : AC(313), Green Tea : CK(4441) : AC(1370)
Diseases : Lipopolysaccharide-Induced Toxicity : CK(2918) : AC(1816), Nonalcoholic fatty liver disease (NAFLD) : CK(3395) : AC(949)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(15129), NF-kappaB Inhibitor : CK(5541) : AC(3360)
Additional Keywords : Gut-liver axis

Anti-obesity effects of Spirulina platensis protein hydrolysate by modulating brain-liver axis in high-fat diet fed mice

Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Spirulina : CK(1015) : AC(291)
Diseases : Obesity : CK(9664) : AC(2565)
Additional Keywords : Anti-Obesity Agents : CK(4281) : AC(1244), Gut-liver axis

Arctic berry extracts target the gut-liver axis to alleviate metabolic endotoxaemia, insulin resistance and hepatic steatosis.

Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Berries: All : CK(5404) : AC(1518), Blueberry : CK(1111) : AC(334), Cloudberry : CK(16) : AC(5), Crowberry : CK(11) : AC(9), Lingonberry : CK(92) : AC(37)
Diseases : Endotoxemia : CK(344) : AC(124), Hepatic Steatosis : CK(434) : AC(180), Insulin Resistance : CK(4532) : AC(1074), Obesity : CK(9664) : AC(2565)
Pharmacological Actions : Hepatoprotective : CK(8320) : AC(3749)
Additional Keywords : Gut-liver axis, Plant Extracts : CK(18030) : AC(6724)

Astaxanthin, Haematococcus pluvialis and Haematococcus pluvialis residue alleviate liver injury in D-galactose-induced aging.

Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Substances : Astaxanthin : CK(1627) : AC(648)
Diseases : Aging : CK(5967) : AC(1435), Liver Damage : CK(3989) : AC(1810), Oxidative Stress : CK(13443) : AC(5439)
Additional Keywords : Gut-liver axis

Baicalin and the liver-gut system: Pharmacological bases explaining its therapeutic effects.

Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(4692) : AC(2171)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3395) : AC(949)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(15129), Gastrointestinal Agents : CK(6875) : AC(2210), NF-kappaB Inhibitor : CK(5541) : AC(3360)
Additional Keywords : Gut-liver axis

Bisphenol A exposure induces gut microbiota dysbiosis and consequent activation of gut-liver axis leading to hepatic steatosis.

Article Published Date : May 28, 2020
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4363) : AC(1306), Dysbiosis : CK(2006) : AC(577), Hepatic Steatosis : CK(434) : AC(180)
Additional Keywords : Gut-liver axis
Problem Substances : Bisphenol A : CK(4552) : AC(1317)

Bisphenol F exposure induces depression-like changes.

Article Published Date : Jan 21, 2024
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4363) : AC(1306), Depression : CK(8817) : AC(1712)
Additional Keywords : Gut-liver axis
Problem Substances : Bisphenol A : CK(4552) : AC(1317)

Blueberry attenuated liver fibrosis, protected intestinal epithelial barrier, and maintained the homeostasis of the gut microbiota.

Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Blueberry : CK(1111) : AC(334)
Diseases : Liver Fibrosis : CK(873) : AC(394)
Pharmacological Actions : Anti-Fibrotic : CK(1964) : AC(1015), Gastrointestinal Agents : CK(6875) : AC(2210), Gastroprotective : CK(1651) : AC(685), Hepatoprotective : CK(8320) : AC(3749)
Additional Keywords : Gut-liver axis

Coffee prevents fatty liver disease induced by a high-fat diet by modulating pathways of the gut-liver axis.

Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Coffee : CK(1649) : AC(207)
Diseases : High Fat Diet : CK(1920) : AC(969), Nonalcoholic fatty liver disease (NAFLD) : CK(3395) : AC(949)
Pharmacological Actions : Gastrointestinal Agents : CK(6875) : AC(2210), Hepatoprotective : CK(8320) : AC(3749)
Additional Keywords : Gut-liver axis

Continued alcohol misuse in human cirrhosis is associated with an impaired gut-liver axis.

Article Published Date : Sep 18, 2017
Study Type : Human Study
Additional Links
Diseases : Alcohol Toxicity : CK(1191) : AC(474), Cirrhosis: Liver : CK(740) : AC(201)
Additional Keywords : Gut-liver axis

Diallyl disulfide ameliorates ethanol-induced liver steatosis and inflammation by maintaining the fatty acid catabolism and regulating the gut-liver axis.

Article Published Date : May 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Organosulfur Compounds : CK(2174) : AC(1021)
Diseases : Alcohol Toxicity : CK(1191) : AC(474), Fatty Liver : CK(4195) : AC(1188), Inflammation : CK(15339) : AC(5190)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(15129), Hepatoprotective : CK(8320) : AC(3749)
Additional Keywords : Gut-liver axis

Dietary approach and gut microbiota modulation for chronic hepatic encephalopathy in cirrhosis.

Article Published Date : Jun 26, 2019
Study Type : Review
Additional Links
Substances : Prebiotics : CK(430) : AC(111), Probiotics : CK(9684) : AC(1695)
Diseases : Cirrhosis : CK(826) : AC(216), Encephalopathy
Therapeutic Actions : Microbiota Transfer Therapy : CK(203) : AC(66)
Pharmacological Actions : Gastrointestinal Agents : CK(6875) : AC(2210)
Additional Keywords : Gut-liver axis, Microbiota : CK(1256) : AC(346)

Diosgenin alleviates nonalcoholic steatohepatitis through affecting liver-gut circulation.

Article Published Date : Dec 31, 2022
Study Type : In Vitro Study
Additional Links
Substances : Diosgenin : CK(245) : AC(146)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3395) : AC(949)
Pharmacological Actions : Hepatoprotective : CK(8320) : AC(3749)
Additional Keywords : Gut-liver axis

Effects of Pu-erh and Dian Hong tea polyphenols on the gut-liver axis.

Article Published Date : Jun 01, 2023
Study Type : Animal Study
Additional Links
Substances : Black Tea : CK(1049) : AC(264)
Diseases : Gastrointestinal Complaints : CK(111) : AC(22)
Pharmacological Actions : Antioxidants : CK(32218) : AC(14096)
Additional Keywords : Gut-liver axis

Eugenol alleviated nonalcoholic fatty liver disease.

Article Published Date : Apr 30, 2022
Study Type : Animal Study
Additional Links
Substances : Eugenol : CK(217) : AC(132)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3395) : AC(949)
Pharmacological Actions : Gastrointestinal Agents : CK(6875) : AC(2210), Hepatoprotective : CK(8320) : AC(3749), Hypolipidemic : CK(8317) : AC(1982)
Additional Keywords : Gut-brain Axis : CK(604) : AC(280), Gut-liver axis

Fecal microbiota transplantation from female donors restores gut permeability and reduces liver injury and inflammation in middle-aged male mice exposed to alcohol.

Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Diseases : Alcoholic Liver Disease : CK(605) : AC(280)
Therapeutic Actions : Microbiota Transfer Therapy : CK(203) : AC(66)
Pharmacological Actions : Hepatoprotective : CK(8320) : AC(3749)
Additional Keywords : Gut-liver axis

Fermented ginseng improved alcohol liver injury in association with changes in the gut microbiota of mice.

Article Published Date : Aug 31, 2019
Study Type : Animal Study
Additional Links
Substances : Fermented Foods and Beverages : CK(3345) : AC(827), Ginseng : CK(4190) : AC(1902)
Diseases : Alcoholic Liver Disease : CK(605) : AC(280)
Pharmacological Actions : Gastrointestinal Agents : CK(6875) : AC(2210), Hepatoprotective : CK(8320) : AC(3749)
Additional Keywords : Gut-liver axis

Folic acid ameliorates alcohol-induced liver injury via gut-liver axis homeostasis.

Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Folic Acid : CK(1315) : AC(205)
Diseases : Alcoholic Liver Disease : CK(605) : AC(280)
Pharmacological Actions : Gastrointestinal Agents : CK(6875) : AC(2210), Hepatoprotective : CK(8320) : AC(3749)
Additional Keywords : Gut-liver axis

Fu brick tea alleviates alcoholic liver injury by modulating the gut microbiota-liver axis.

Article Published Date : Sep 21, 2022
Study Type : Animal Study
Additional Links
Substances : Black Tea : CK(1049) : AC(264)
Diseases : Alcoholic Liver Disease : CK(605) : AC(280), Lipopolysaccharide-Induced Toxicity : CK(2918) : AC(1816)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(15129), Antioxidants : CK(32218) : AC(14096), Gastrointestinal Agents : CK(6875) : AC(2210), Hepatoprotective : CK(8320) : AC(3749), NF-kappaB Inhibitor : CK(5541) : AC(3360)
Additional Keywords : Gut-liver axis

Fucoidan from Apostichopus japonicus ameliorates alcoholic liver disease by regulating gut-liver axis homeostasis.

Article Published Date : May 03, 2024
Study Type : Animal Study
Additional Links
Substances : Fucoidan : CK(866) : AC(451)
Diseases : Alcoholic Liver Disease : CK(605) : AC(280)
Pharmacological Actions : Hepatoprotective : CK(8320) : AC(3749)
Additional Keywords : Gut-liver axis

Ginsenoside Rh4 improves hepatic lipid metabolism and inflammation in a model of NAFLD.

Article Published Date : Jun 25, 2023
Study Type : Animal Study
Additional Links
Substances : Ginsenosides : CK(2640) : AC(1452)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3395) : AC(949)
Pharmacological Actions : Hepatoprotective : CK(8320) : AC(3749), Hypolipidemic : CK(8317) : AC(1982)
Additional Keywords : Gut-liver axis

Glucopyranose from Pleurotus geesteranus prevent alcoholic liver diseases by regulating Nrf2/HO-1-TLR4/NF-κB signalling pathways and gut microbiota.

Article Published Date : Jan 19, 2022
Study Type : Animal Study
Additional Links
Substances : Medicinal Mushrooms : CK(2637) : AC(1233)
Diseases : Alcoholic Liver Disease : CK(605) : AC(280)
Pharmacological Actions : Antioxidants : CK(32218) : AC(14096), Gastrointestinal Agents : CK(6875) : AC(2210), Heme oxygenase-1 up-regulation : CK(1225) : AC(755), Nrf2 activation : CK(2908) : AC(1761)
Additional Keywords : Gut-liver axis

Gut microbiota and liver metabolomics reveal the potential mechanism of Lactobacillus rhamnosus GG modulating the liver toxicity caused by polystyrene microplastics.

Article Published Date : Dec 27, 2023
Study Type : Animal Study
Additional Links
Substances : Lactobacillus rhamnosus GG : CK(660) : AC(147)
Diseases : Chemically-Induced Liver Damage : CK(2167) : AC(1056), Microplastic Toxicity : CK(514) : AC(341)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(15129), Gastrointestinal Agents : CK(6875) : AC(2210), Hepatoprotective : CK(8320) : AC(3749), Interleukin-6 Downregulation : CK(9048) : AC(3503), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(10605) : AC(4635)
Additional Keywords : Gut-liver axis

Gut microbiota participates in polystyrene microplastics-induced hepatic injuries.

Article Published Date : Aug 07, 2023
Study Type : Animal Study
Additional Links
Diseases : Chemically-Induced Liver Damage : CK(2167) : AC(1056), Inflammation : CK(15339) : AC(5190), Microplastic Toxicity : CK(514) : AC(341)
Pharmacological Actions : Gastroprotective : CK(1651) : AC(685)
Additional Keywords : Gut-liver axis
Problem Substances : Polystyrene nanoparticles : CK(426) : AC(211)

Gut-liver axis modulation of Panax notoginseng saponins in nonalcoholic fatty liver disease.

Article Published Date : Mar 02, 2021
Study Type : Animal Study
Additional Links
Substances : Panax Notoginseng : CK(392) : AC(185)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3395) : AC(949)
Pharmacological Actions : Hepatoprotective : CK(8320) : AC(3749)
Additional Keywords : Gut-liver axis

Hepatoprotective effect of curcumin against bisphenol A-induced hepatic steatosis.

Article Published Date : Jun 29, 2022
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(6902) : AC(3212)
Diseases : Bisphenol Toxicity : CK(4363) : AC(1306), Chemically-Induced Liver Damage : CK(2167) : AC(1056)
Pharmacological Actions : Hepatoprotective : CK(8320) : AC(3749)
Additional Keywords : Gut-liver axis
Problem Substances : Bisphenol A : CK(4552) : AC(1317)

Hepatoprotective effect of probiotic Lactobacillus rhamnosus GG in a model of alcoholic liver disease.

Article Published Date : Jun 25, 2019
Study Type : Animal Study
Additional Links
Substances : Lactobacillus rhamnosus GG : CK(660) : AC(147)
Diseases : Alcoholic Liver Disease : CK(605) : AC(280)
Pharmacological Actions : Gastrointestinal Agents : CK(6875) : AC(2210), Hepatoprotective : CK(8320) : AC(3749)
Additional Keywords : Gut-liver axis

Hericium erinaceus polysaccharides ameliorate nonalcoholic fatty liver disease.

Article Published Date : Jun 30, 2024
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus) : CK(262) : AC(136)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3395) : AC(949)
Pharmacological Actions : Gastrointestinal Agents : CK(6875) : AC(2210)
Additional Keywords : Gut-liver axis, Polysaccharides : CK(1251) : AC(746)

Intermittent fasting, especially when associated with coconut oil, had effects comparable with caloric restriction in modulating the parameters of the gut-liver axis.

Article Published Date : Jan 31, 2024
Study Type : Animal Study
Additional Links
Substances : Coconut Oil : CK(478) : AC(106)
Diseases : Obesity : CK(9664) : AC(2565)
Therapeutic Actions : Fasting/Caloric Restriction : CK(798) : AC(172)
Additional Keywords : Gut-liver axis

L. reuteri ZJ617 inhibits inflammatory and autophagy signaling pathways in gut-liver axis in piglet induced by lipopolysaccharide.

Article Published Date : Oct 12, 2021
Study Type : Animal Study
Additional Links
Substances : Lactobacillus reuteri : CK(617) : AC(123)
Diseases : Lipopolysaccharide-Induced Toxicity : CK(2918) : AC(1816)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(15129)
Additional Keywords : Gut-liver axis

Lactobacillus fermentum CQPC06 prevents non-alcoholic fatty liver disease by stabilizing the gut-liver axis.

Article Published Date : Oct 20, 2020
Study Type : Animal Study
Additional Links
Substances : Lactobacillus fermentum : CK(224) : AC(94)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3395) : AC(949)
Pharmacological Actions : Gastrointestinal Agents : CK(6875) : AC(2210), Hepatoprotective : CK(8320) : AC(3749)
Additional Keywords : Gut-liver axis

Lactobacillus gasseri CKCC1913 mediated modulation of the gut-liver axis alleviated insulin resistance and liver damage induced by type 2 diabetes.

Article Published Date : Sep 18, 2023
Study Type : Animal Study
Additional Links
Substances : Lactobacillus gasseri : CK(209) : AC(46)
Diseases : Diabetes Mellitus: Type 2 : CK(11728) : AC(2489), Insulin Resistance : CK(4532) : AC(1074)
Pharmacological Actions : Antioxidants : CK(32218) : AC(14096), Hepatoprotective : CK(8320) : AC(3749)
Additional Keywords : Gut-liver axis

Lactobacillus plantarum 69-2 combined with galacto-oligosaccharides alleviates d-galactose-induced aging.

Article Published Date : Mar 09, 2021
Study Type : Animal Study
Additional Links
Substances : Galacto-oligosaccharides : CK(68) : AC(10), Lactobacillus plantarum : CK(992) : AC(304)
Diseases : Aging : CK(5967) : AC(1435)
Pharmacological Actions : Antioxidants : CK(32218) : AC(14096), Gastrointestinal Agents : CK(6875) : AC(2210), Hepatoprotective : CK(8320) : AC(3749), SIRT1 Activator : CK(349) : AC(183)
Additional Keywords : Gut-liver axis

Lupeol improves bile acid metabolism and metabolic dysfunction-associated steatotic liver disease.

Article Published Date : Jun 16, 2024
Study Type : Animal Study
Additional Links
Substances : Lupeol : CK(122) : AC(68)
Diseases : Liver Disease : CK(350) : AC(111)
Pharmacological Actions : Hepatoprotective : CK(8320) : AC(3749)
Additional Keywords : Gut-liver axis

Lycopene attenuates western-diet-induced cognitive deficits via improving glycolipid metabolism dysfunction and inflammatory responses in gut-liver-brain axis.

Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Lycopene : CK(1264) : AC(370)
Diseases : Cognitive Decline/Dysfunction : CK(5053) : AC(999)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(15129)
Additional Keywords : Gut-brain Axis : CK(604) : AC(280), Gut-liver axis
Anti Therapeutic Actions : Western Diet : CK(601) : AC(151)

Melatonin improves cholestatic liver disease via the gut-liver axis.

Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Substances : Melatonin : CK(2743) : AC(899)
Diseases : Cholestasis : CK(163) : AC(53), Liver Cirrhosis : CK(893) : AC(221), Liver Disease : CK(350) : AC(111)
Pharmacological Actions : Gastrointestinal Agents : CK(6875) : AC(2210)
Additional Keywords : Gut-liver axis

Morinda citrifolia extract prevents alcoholic fatty liver disease by improving gut health.

Article Published Date : Nov 30, 2022
Study Type : Animal Study
Additional Links
Substances : Noni : CK(242) : AC(104)
Diseases : Alcoholic Liver Disease : CK(605) : AC(280), Inflammation : CK(15339) : AC(5190)
Pharmacological Actions : Gastrointestinal Agents : CK(6875) : AC(2210), Hepatoprotective : CK(8320) : AC(3749)
Additional Keywords : Gut-liver axis

MUP1 mediates urolithin A alleviation of chronic alcohol-related liver disease via gut-microbiota-liver axis.

Article Published Date : Dec 31, 2023
Study Type : Animal Study
Additional Links
Substances : Urolithin A : CK(247) : AC(128)
Diseases : Alcoholic Liver Disease : CK(605) : AC(280)
Pharmacological Actions : Hepatoprotective : CK(8320) : AC(3749)
Additional Keywords : Gut-liver axis

Paeoniflorin recued hepatotoxicity under zinc oxide nanoparticles exposure.

Article Published Date : Sep 07, 2023
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin : CK(559) : AC(364)
Diseases : Chemically-Induced Liver Damage : CK(2167) : AC(1056)
Pharmacological Actions : Hepatoprotective : CK(8320) : AC(3749)
Additional Keywords : Gut-liver axis
Problem Substances : Zinc Oxide : CK(30) : AC(15)

Phyllanthus emblica fruit improves obesity by reducing appetite and enhancing mucosal homeostasis.

Article Published Date : May 07, 2024
Study Type : Animal Study
Additional Links
Substances : Amla Fruit : CK(265) : AC(94)
Diseases : Obesity : CK(9664) : AC(2565)
Pharmacological Actions : Appetite Depressants : CK(84) : AC(14), Gastrointestinal Agents : CK(6875) : AC(2210)
Additional Keywords : Anti-Obesity Agents : CK(4281) : AC(1244), Gut-liver axis, Plant Extracts : CK(18030) : AC(6724)

Polystyrene nanoplastics exacerbate aflatoxin B1-induced hepatic injuries by modulating the gut-liver axis.

Article Published Date : Jul 19, 2024
Study Type : Animal Study
Additional Links
Diseases : Chemically-Induced Liver Damage : CK(2167) : AC(1056), Liver Damage: Aflatoxin-Induced : CK(100) : AC(46), Microplastic Toxicity : CK(514) : AC(341)
Additional Keywords : Gut-liver axis, Increased Risk : CK(8492) : AC(1106)
Problem Substances : Nano Plastic-and Micro-Particles : CK(62) : AC(90), Polystyrene nanoparticles : CK(426) : AC(211)

Polystyrene nanoplastics induce intestinal and hepatic inflammation through activation of NF-κB/NLRP3 pathways and related gut-liver axis.

Article Published Date : Jul 19, 2024
Study Type : Animal Study
Additional Links
Diseases : Chemically-Induced Liver Damage : CK(2167) : AC(1056), Inflammation : CK(15339) : AC(5190), Microplastic Toxicity : CK(514) : AC(341)
Additional Keywords : Gut-liver axis
Problem Substances : Nano Plastic-and Micro-Particles : CK(62) : AC(90), Polystyrene nanoparticles : CK(426) : AC(211)

Seabuckthorn polysaccharide ameliorates high-fat diet-induced obesity.

Article Published Date : Mar 06, 2022
Study Type : Animal Study
Additional Links
Substances : Sea buckthorn : CK(366) : AC(146)
Diseases : Obesity : CK(9664) : AC(2565)
Pharmacological Actions : Gastrointestinal Agents : CK(6875) : AC(2210)
Additional Keywords : Anti-Obesity Agents : CK(4281) : AC(1244), Gut-liver axis

sesamol could be a potential neuroprotective agent during aging process due to its beneficial effects on liver-brain axis.

Article Published Date : Nov 13, 2018
Study Type : Animal Study
Additional Links
Substances : Sesamol : CK(229) : AC(136)
Diseases : Brain: Oxidative Stress : CK(635) : AC(345), Cognitive Decline/Dysfunction : CK(5053) : AC(999)
Pharmacological Actions : Antioxidants : CK(32218) : AC(14096), Brain-derived neurotrophic factor modulator : CK(719) : AC(270), Interleukin-1 beta downregulation : CK(5277) : AC(2826), Neuroprotective Agents : CK(17667) : AC(7609), Nrf2 activation : CK(2908) : AC(1761), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(10605) : AC(4635)
Additional Keywords : Gut-liver axis

Silibinin decreases hepatic glucose production through the activation of gut-brain-liver axis in diabetic rats.

Article Published Date : Sep 18, 2018
Study Type : Animal Study
Additional Links
Substances : Silibinin : CK(460) : AC(231)
Diseases : Diabetes Mellitus: Type 2 : CK(11728) : AC(2489), Obesity : CK(9664) : AC(2565)
Pharmacological Actions : Hypoglycemic Agents : CK(8194) : AC(2016)
Additional Keywords : Gut-liver axis

Sulforaphane ameliorates nonalcoholic fatty liver disease induced by high-fat and high-fructose diet.

Article Published Date : Jan 31, 2023
Study Type : Animal Study
Additional Links
Substances : Sulforaphane : CK(1333) : AC(629)
Diseases : High Fat Diet : CK(1920) : AC(969), High Sugar Diet : CK(480) : AC(125), Inflammation : CK(15339) : AC(5190), Lipopolysaccharide-Induced Toxicity : CK(2918) : AC(1816), Nonalcoholic fatty liver disease (NAFLD) : CK(3395) : AC(949)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(15129), Hepatoprotective : CK(8320) : AC(3749)
Additional Keywords : Gut-liver axis, Risk Reduction : CK(17851) : AC(1994)

The improvement of intestinal dysbiosis and hepatic metabolic dysfunction in dextran sulfate sodium-induced colitis.

Article Published Date : Jul 31, 2023
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(6902) : AC(3212)
Diseases : Colitis : CK(1493) : AC(714), Inflammatory Bowel Diseases : CK(3151) : AC(909)
Pharmacological Actions : Gastrointestinal Agents : CK(6875) : AC(2210), Hepatoprotective : CK(8320) : AC(3749)
Additional Keywords : Gut-liver axis

The links between the gut microbiome and non-alcoholic fatty liver disease (NAFLD).

Article Published Date : Jan 24, 2019
Study Type : Review
Additional Links
Substances : Probiotics : CK(9684) : AC(1695)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3395) : AC(949)
Additional Keywords : Gut-liver axis

These results suggest a potential relevance of vitamin D as a therapeutic agent acting on the gut-liver axis.

Article Published Date : Jan 02, 2019
Study Type : Animal Study
Additional Links
Substances : Vitamin D : CK(11543) : AC(1677)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(3395) : AC(949)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(15129), Hepatoprotective : CK(8320) : AC(3749)
Additional Keywords : Gut-liver axis

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