Results for Cruciferous Vegetables

Authors conclude that data from this study provides evidence for the use of sulforaphane in preventing stroke in selected high-risk patient cohorts.

Article Published Date : Jan 01, 2018
Study Type : Animal Study
Additional Links
Substances : Sulforaphane : CK(1344) : AC(630)
Diseases : Stroke : CK(4410) : AC(773)
Pharmacological Actions : Platelet aggregation inhibitor: collagen-induced aggregation : CK(3) : AC(2)
Additional Keywords : Broccoli : CK(89) : AC(26), Broccoli Sprouts, Cruciferous Vegetables

Free radicals enhance the activation of Antioxidant Response Element (ARE) by sulforaphane, despite suppression of Nrf2 nuclear accumulation.

Article Published Date : Jan 20, 2018
Study Type : Human In Vitro
Additional Links
Substances : Sulforaphane : CK(1344) : AC(630)
Diseases : Oxidative Stress : CK(14758) : AC(5716)
Pharmacological Actions : Antioxidant Effects : CK(159) : AC(45), Nrf2 activation : CK(3156) : AC(1794)
Additional Keywords : Antioxidants : CK(303) : AC(126), Broccoli : CK(89) : AC(26), Broccoli Sprouts, Cruciferous Vegetables

Given its anticarcinogenic, anti-inflammatory, antioxidant properties, these authors conclude that sulforaphane could be considered as a phytochemical at the forefront of natural medicine.

Article Published Date : May 23, 2018
Study Type : Review
Additional Links
Substances : Sulforaphane : CK(1344) : AC(630)
Diseases : Cancers, Oxidative Stress : CK(14758) : AC(5716)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39737) : AC(15858), Anticarcinogenic Agents : CK(2152) : AC(1018), Antioxidant Effects : CK(159) : AC(45), Apoptotic : CK(9585) : AC(7379), NF-E2-Related Factor-2 (Nrf2) Modulator : CK(72) : AC(41), NF-kappaB Inhibitor : CK(5952) : AC(3464)
Additional Keywords : Broccoli : CK(89) : AC(26), Broccoli Sprouts, Cruciferous Vegetables, Isothiocyanates : CK(254) : AC(104)

If You're Concerned About Breast Cancer...What You Must Know

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Wednesday, October 17, 2012 - 08:00
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As most of us know, October is Breast Cancer Awareness month. Dr. Helayne Waldman is the co-author (with Dr. Ed Bauman) of a new book called THE WHOLE FOOD GUIDE FOR BREAST CANCER SURVIVORS. According to the authors, the book is not just for survivors of cancer, but for anyone who wants to reduce their chances of becoming a cancer statistic in the first place. In honor of Breast Cancer Awareness month, Drs. Waldman and Bauman have allowed us to share a chapter from their book, which we're proud to reprint here at GreenMedInfo. For further info about this wonderful resource, check out www.wholefoodguideforbreastcancer.com.

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Most Cheese Products Tainted with Dangerous Plastic Chemicals, Study Reveals

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Tuesday, July 18, 2017 - 16:09
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A University of Washington study involving cheese products found endocrine-disrupting phthalates present in 29 of 30 samples tested

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Sulforaphane attentuates cadmium-induced carcinogenesis through Nrf2, antioxidant, and autophagy mechanisms.

Article Published Date : Jan 15, 2018
Study Type : Human In Vitro
Additional Links
Substances : Sulforaphane : CK(1344) : AC(630)
Diseases : Cadmium Poisoning : CK(439) : AC(225), Cancers
Pharmacological Actions : Anticarcinogenic Agents : CK(2152) : AC(1018), Antioxidant, Antioxidant Effects : CK(159) : AC(45), Apoptotic : CK(9585) : AC(7379), Autophagy Up-regulation : CK(838) : AC(559), NF-E2-Related Factor-2 (Nrf2) Modulator : CK(72) : AC(41)
Additional Keywords : Broccoli : CK(89) : AC(26), Broccoli Sprouts, Cruciferous Vegetables, Isothiocyanates : CK(254) : AC(104)

Sulforaphane combats colon cancer in vitro by inhibiting COX-2 and prostaglandin E1 synthase and exhibiting anti-angiogenic, anti-proliferative, and anti-metastatic properties.

Article Published Date : Jan 01, 2018
Study Type : Human In Vitro
Additional Links
Substances : Sulforaphane : CK(1344) : AC(630)
Diseases : Colon Cancer : CK(1920) : AC(1203)
Pharmacological Actions : Anti-Angiogenic : CK(421) : AC(284), Anti-cancer : CK(23) : AC(6), Anti-metastatic : CK(2870) : AC(2182), Anti-Proliferative : CK(68) : AC(56), Cyclooxygenase 2 Inhibitors : CK(2264) : AC(1327), Hypoxia-inducible factor-1 (HIF-1) inhibitor : CK(89) : AC(33), Prostaglandin E Synthase-1 (PGES-1) Down-Regulation : CK(9) : AC(3)
Additional Keywords : Broccoli : CK(89) : AC(26), Broccoli Sprouts, Cruciferous Vegetables

Sulforaphane detoxifies benzene, an air pollutant, in a dose-dependent manner and may attentuate attenuate associated long-term health risks of air pollution.

Article Published Date : Jul 03, 2019
Study Type : Human Study
Additional Links
Substances : Broccoli Sprouts : CK(303) : AC(55), Sulforaphane : CK(1344) : AC(630)
Diseases : Air Pollution Linked Toxicity : CK(4976) : AC(742), Benzene Toxicity : CK(70) : AC(22)
Pharmacological Actions : Antioxidant Effects : CK(159) : AC(45), Detoxifier : CK(856) : AC(254)
Additional Keywords : Airborne Pollution : CK(49) : AC(9), Broccoli : CK(89) : AC(26), Broccoli Sprouts, Cruciferous Vegetables, Dose Response : CK(1770) : AC(700), Environmental Pollutant : CK(80) : AC(37), Environmental Pollution
Problem Substances : Airborne Pollution : CK(36) : AC(7), Benzene : CK(206) : AC(37)

Sulforaphane elicits antioxidant, anti-inflammatory, and extracellular matrix remodelling effects in a rat model of diabetic peripheral neuropathy.

Article Published Date : Aug 01, 2018
Study Type : Animal Study
Additional Links
Substances : Sulforaphane : CK(1344) : AC(630)
Diseases : Inflammation : CK(16094) : AC(5496), Oxidative Stress : CK(14758) : AC(5716)
Pharmacological Actions : Cyclooxygenase 2 Inhibitors : CK(2264) : AC(1327), Interleukin-10 upregulation : CK(1296) : AC(436), Malonaldehyde (MDA) Down-Regulation : CK(65) : AC(17), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(944) : AC(588), Neuroprotective Agents : CK(20061) : AC(7949), NF-kappaB Inhibitor : CK(5952) : AC(3464), Nitric Oxide Inhibitor : CK(705) : AC(356), Superoxide Dismutase Up-regulation : CK(2383) : AC(928)
Additional Keywords : Broccoli : CK(89) : AC(26), Broccoli Sprouts, Cruciferous Vegetables, Isothiocyanates : CK(254) : AC(104)

Sulforaphane enhances leptin sensitivity and prevents weigh gain in diet-induced obese mice.

Article Published Date : Sep 15, 2018
Study Type : Animal Study
Additional Links
Substances : Sulforaphane : CK(1344) : AC(630)
Diseases : Obesity : CK(11004) : AC(2672)
Additional Keywords : Body Mass Index (BMI) : CK(22) : AC(3), Broccoli : CK(89) : AC(26), Broccoli Sprouts, Cruciferous Vegetables, Isothiocyanates : CK(254) : AC(104), leptin

Sulforaphane has the potential to prevent neuronal disorders by enhancing Brain-derived Neurotrophic Factor (BDNF) and its TrkB signaling pathways.

Article Published Date : Jan 01, 2017
Study Type : Animal Study
Additional Links
Substances : Sulforaphane : CK(1344) : AC(630)
Diseases : Neurodegenerative Diseases : CK(13103) : AC(4279)
Pharmacological Actions : Brain-derived neurotrophic factor modulator : CK(745) : AC(280)
Additional Keywords : Broccoli : CK(89) : AC(26), Broccoli Sprouts, Cruciferous Vegetables, Epigenetic Modification : CK(566) : AC(214), Isothiocyanates : CK(254) : AC(104)

Sulforaphane improves LPS-induced spatial learning and memory dysfunction, likely by upregulating neurogenesis through the BDNF-mTOR pathway.

Article Published Date : Jan 15, 2018
Study Type : Animal Study
Additional Links
Substances : Sulforaphane : CK(1344) : AC(630)
Diseases : Inflammation : CK(16094) : AC(5496), Lipopolysaccharide-Induced Toxicity : CK(3229) : AC(1875), Memory Disorders : CK(1795) : AC(559)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39737) : AC(15858), Neurogenesis : CK(325) : AC(173)
Additional Keywords : Brain-derived neurotrophic factor modulator, Broccoli : CK(89) : AC(26), Broccoli Sprouts, Cruciferous Vegetables, Isothiocyanates : CK(254) : AC(104)

Sulforaphane inhibited proliferation of bladder cancer cells by 29.7 ± 4.6% under normal oxygen conditions and 48.3 ± 5.2% under hypoxic conditions through suppression of HIF-1α-mediated glycolysis.

Article Published Date : Jul 17, 2019
Study Type : In Vitro Study
Additional Links
Substances : Broccoli Sprouts : CK(303) : AC(55), Sulforaphane : CK(1344) : AC(630)
Diseases : Bladder Cancer : CK(782) : AC(320)
Pharmacological Actions : Antiproliferative : CK(10001) : AC(7491), Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor : CK(363) : AC(237)
Additional Keywords : Anti-cancer, Antiproliferative : CK(75) : AC(61), Broccoli : CK(89) : AC(26), Cruciferous Vegetables, Hypoxia : CK(5) : AC(4)

Sulforaphane inhibits pancreatic cancer proliferation through AMPK activation and Nrf2 translocation in vitro and in vivo.

Article Published Date : Jan 01, 2018
Study Type : Animal Study
Additional Links
Substances : Sulforaphane : CK(1344) : AC(630)
Diseases : Pancreatic Cancer : CK(1547) : AC(564)
Pharmacological Actions : Anti-Tumor : CK(167) : AC(78), Anticarcinogenic Agents : CK(2152) : AC(1018), Antiproliferative : CK(10001) : AC(7491), Apoptotic : CK(9585) : AC(7379), Nrf2 activation : CK(3156) : AC(1794)
Additional Keywords : Broccoli : CK(89) : AC(26), Broccoli Sprouts, Cruciferous Vegetables, Isothiocyanates : CK(254) : AC(104)

Sulforaphane is a promising agent to restore glucose tolerance through upregulation of insulin signaling in obese mice.

Article Published Date : Sep 19, 2018
Study Type : Animal Study
Additional Links
Substances : Sulforaphane : CK(1344) : AC(630)
Diseases : Insulin Resistance : CK(4864) : AC(1098)
Pharmacological Actions : Glucose Uptake Optimization : CK(26) : AC(9), Insulin Sensitizers : CK(1957) : AC(422)
Additional Keywords : Broccoli : CK(89) : AC(26), Broccoli Sprouts, Cruciferous Vegetables, Isothiocyanates : CK(254) : AC(104)
Problem Substances : Insulin : CK(502) : AC(87)

Sulforaphane pre-treatment effectively protects bovine ovarian granulosa cells from oxidative stress damage through Nrf2-ARE activation.

Article Published Date : Dec 01, 2018
Study Type : In Vitro Study
Additional Links
Substances : Sulforaphane : CK(1344) : AC(630)
Diseases : Oxidative Stress : CK(14758) : AC(5716)
Pharmacological Actions : Antioxidant Effects : CK(159) : AC(45), Nrf2 activation : CK(3156) : AC(1794)
Additional Keywords : Broccoli : CK(89) : AC(26), Broccoli Sprouts, Cruciferous Vegetables, Isothiocyanates : CK(254) : AC(104)

Sulforaphane prevents hepatic insulin resistance through a ceramide-dependent mechanism.

Article Published Date : May 27, 2019
Study Type : Human In Vitro
Additional Links
Substances : Broccoli Sprouts : CK(303) : AC(55), Sulforaphane : CK(1344) : AC(630)
Diseases : Diabetes Mellitus: Type 2 : CK(12953) : AC(2579), Insulin Disorders : CK(26) : AC(10), Insulin Resistance : CK(4864) : AC(1098)
Pharmacological Actions : Glucose Uptake Optimization : CK(26) : AC(9), Insulin Sensitizers : CK(1957) : AC(422)
Additional Keywords : Broccoli : CK(89) : AC(26), Cruciferous Vegetables, glucose control, Glucose Uptake Enhancement : CK(7) : AC(2)

Sulforaphane protects against cadmium-induced testicular injury by activation of Nrf2-ARE pathway.

Article Published Date : Jul 19, 2018
Study Type : Animal Study
Additional Links
Substances : Sulforaphane : CK(1344) : AC(630)
Diseases : Heavy Metal Toxicity : CK(2713) : AC(1036), Oxidative Stress : CK(14758) : AC(5716), Testicular Injury: Cadmium-Induced : CK(41) : AC(21)
Pharmacological Actions : Antioxidants : CK(34551) : AC(14499), Apoptotic : CK(9585) : AC(7379)
Additional Keywords : Broccoli : CK(89) : AC(26), Broccoli Sprouts, Cruciferous Vegetables, Isothiocyanates : CK(254) : AC(104)

Sulforaphane protects against ethanol-induced apoptosis in neural crest cells, a characteristic of Fetal Alcohol Syndrome, through restoration of Snail1 expression and epithelial-mesenchymal transition.

Article Published Date : Jul 08, 2019
Study Type : Human In Vitro
Additional Links
Substances : Sulforaphane : CK(1344) : AC(630)
Diseases : Fetal Alcoholism : CK(21) : AC(5)
Pharmacological Actions : Anti-Apoptotic : CK(5568) : AC(3160), Neuroprotective Agents : CK(20061) : AC(7949)
Additional Keywords : Alcohol, Broccoli : CK(89) : AC(26), Broccoli Sprouts, Cruciferous Vegetables, Mesenchymal Stem Cells : CK(167) : AC(103), Pregnancy And Fetal Growth : CK(163) : AC(37)

Sulforaphane protects against intermittent hypoxia-induced cardiomyopathy through Nrf2 activation.

Article Published Date : Jan 10, 2018
Study Type : Animal Study
Additional Links
Substances : Sulforaphane : CK(1344) : AC(630)
Diseases : Cardiomyopathy : CK(362) : AC(162), Hypoxia : CK(436) : AC(244)
Pharmacological Actions : Antioxidant Effects : CK(159) : AC(45), Metallothionein Up-regulation : CK(12) : AC(2), Nrf2 activation : CK(3156) : AC(1794)
Additional Keywords : Broccoli : CK(89) : AC(26), Broccoli Sprouts, Cruciferous Vegetables, Isothiocyanates : CK(254) : AC(104)

Sulforaphane protects against oxidative stress in culture of adult cardiomyocytes.

Article Published Date : Aug 01, 2018
Study Type : Human In Vitro
Additional Links
Substances : Sulforaphane : CK(1344) : AC(630)
Diseases : Lipid Peroxidation : CK(2054) : AC(804), Oxidative Stress : CK(14758) : AC(5716)
Pharmacological Actions : Antioxidants : CK(34551) : AC(14499), Nrf2 activation : CK(3156) : AC(1794)
Additional Keywords : Broccoli : CK(89) : AC(26), Broccoli Sprouts, Cruciferous Vegetables, Isothiocyanates : CK(254) : AC(104)

Sulforaphane's anti-inflammatory, antioxidant, and neuroprotective benefits attentuate autoimmune encephalomyelitis in an animal model of Multiple Sclerosis.

Article Published Date : Jul 22, 2019
Study Type : Animal Study
Additional Links
Substances : Sulforaphane : CK(1344) : AC(630)
Diseases : Autoimmune Diseases : CK(12040) : AC(2692), Multiple Sclerosis : CK(2432) : AC(557)
Therapeutic Actions : anti-inflammatory, antioxidant, neuro-protective
Pharmacological Actions : Anti-Inflammatory Agents : CK(39737) : AC(15858), Antioxidant Effects : CK(159) : AC(45), Neuroprotective Agents : CK(20061) : AC(7949), Nitric Oxide Inhibitor : CK(705) : AC(356)
Additional Keywords : Antioxidant : CK(17) : AC(5), Autoimmune Diseases, Cruciferous Vegetables, Multiple Sclerosis : CK(38) : AC(8), Phytotherapy : CK(4003) : AC(1031), Sulforaphane

Sulforaphene inhibits liver cancer cell proliferation by stimulating apoptosis and causing cytotoxicity.

Article Published Date : Jun 04, 2018
Study Type : Human In Vitro
Additional Links
Substances : Sulforaphane : CK(1344) : AC(630)
Diseases : Liver Cancer : CK(3119) : AC(1641)
Pharmacological Actions : Antiproliferative : CK(10001) : AC(7491), Apoptotic : CK(9585) : AC(7379)
Additional Keywords : Broccoli : CK(89) : AC(26), Broccoli Sprouts, Cruciferous Vegetables, Isothiocyanates : CK(254) : AC(104)

Sulforphane exhibits immunomodulatory properties on human placenta cells in vitro.

Article Published Date : Feb 01, 2019
Study Type : Human In Vitro
Additional Links
Substances : Sulforaphane : CK(1344) : AC(630)
Pharmacological Actions : Anti-Inflammatory Agents : CK(39737) : AC(15858), Immune Enhancing Properties : CK(18) : AC(5)
Additional Keywords : Broccoli : CK(89) : AC(26), Broccoli Sprouts, Cruciferous Vegetables, Pregnancy : CK(217) : AC(44)

Sulforphane's antioxidant properties make it an effective neuroprotective agent. More studies are needed to determine the exact implications in neurological disease.

Article Published Date : Apr 01, 2019
Study Type : Review
Additional Links
Substances : Sulforaphane : CK(1344) : AC(630)
Therapeutic Actions : antioxidant, antioxidants, neuro-protective
Pharmacological Actions : Antioxidant, Antioxidant Effects : CK(159) : AC(45), Antioxidants : CK(34551) : AC(14499), Neuroprotective Agents : CK(20061) : AC(7949), NF-E2-Related Factor-2 (Nrf2) Modulator : CK(72) : AC(41), Nrf2 activation : CK(3156) : AC(1794)
Additional Keywords : Antioxidant effects, Antioxidant Systems : CK(3) : AC(3), Cruciferous Vegetables, Neurodegenerative diseases, Neuroprotective Agents, Nrf2 activation, Phytotherapy : CK(4003) : AC(1031), Sulforaphane

This review establishes sulforaphane as a safe and non-toxic chemopreventative agent and indicates the need for more research for its use in human cancers as a single agent or as part of combination therapy.

Article Published Date : Jan 01, 2018
Study Type : Review
Additional Links
Substances : Sulforaphane : CK(1344) : AC(630)
Diseases : Cancers
Pharmacological Actions : Anticarcinogenic Agents : CK(2152) : AC(1018), Antiproliferative : CK(10001) : AC(7491), Apoptotic : CK(9585) : AC(7379), Phase II Detoxification Enzyme Inducer : CK(100) : AC(55)
Additional Keywords : Broccoli : CK(89) : AC(26), Broccoli Sprouts, Cruciferous Vegetables, Isothiocyanates : CK(254) : AC(104)

This study elucidates the mechanisms behind the neurovascular protective effects of sulforaphane.

Article Published Date : Aug 23, 2018
Study Type : In Vitro Study
Additional Links
Substances : Sulforaphane : CK(1344) : AC(630)
Pharmacological Actions : Antioxidant Effects : CK(159) : AC(45), Glucose Uptake Optimization : CK(26) : AC(9), Phase II Detoxification Enzyme Inducer : CK(100) : AC(55)
Additional Keywords : Broccoli : CK(89) : AC(26), Broccoli Sprouts, Cruciferous Vegetables, Drug Metabolism : CK(14) : AC(4), Mitochondria : CK(17) : AC(9), Mitochondrial Biogenesis : CK(51) : AC(18)

Top 10 Reasons to Eat Your Cruciferous Veggies

Post date:
Tuesday, June 4, 2019 - 04:00
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10 Reasons to Eat Your Cruciferous Vegetables

Everyone knows that eating vegetables has profound health benefits. But, like all foods, not all vegetables are created the same. A few vegetables appear to be downright "miracle" foods!

One such group of veggies are those of the Brassica family; commonly known as cruciferous. These include broccoli, Brussels sprouts, cabbage, cauliflower, kale, radish, rutabaga, turnip and even arugula. 

What makes this group of veggies so special? Sulforaphane. 

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Week-long oral administration of sulforaphane increased blood and thalamic glutathione levels in healthy human subjects.

Article Published Date : May 01, 2018
Study Type : Human Study
Additional Links
Substances : Sulforaphane : CK(1344) : AC(630)
Diseases : Psychiatric Disorders : CK(362) : AC(95)
Pharmacological Actions : Glutathione Upregulation : CK(359) : AC(110)
Additional Keywords : Broccoli : CK(89) : AC(26), Broccoli Sprouts, Cruciferous Vegetables, psychiatric disorders

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