Results for Chemotherapeutic

A comprehensive review on anticancer mechanisms of crocin.

Article Published Date : Jul 02, 2017
Study Type : Review
Additional Links
Substances : Crocin : CK(732) : AC(311)
Diseases : Cancers: All : CK(36285) : AC(14319)
Pharmacological Actions : Anti-metastatic : CK(2865) : AC(2178), Antiproliferative : CK(9975) : AC(7471), Apoptotic : CK(9570) : AC(7368), Chemotherapeutic : CK(4337) : AC(1618), Telomerase Inhibitor : CK(98) : AC(65)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Apoptotic, Cancers: All, Chemotherapeutic, Crocin, Telomerase Inhibitor

A treatment approach including intravenous α-lipoic acid and low-dose naltrexone led to stable disease in this patient.

Article Published Date : Nov 30, 2017
Study Type : Human: Case Report
Additional Links
Substances : Alpha-Lipoic Acid : CK(1501) : AC(366), Vitamin C: Intravenous : CK(404) : AC(60)
Diseases : Kidney Cancer : CK(388) : AC(181)
Pharmacological Actions : Chemopreventive : CK(6568) : AC(2159), Chemotherapeutic : CK(4337) : AC(1618)
Additional Keywords : Alpha-Lipoic Acid, Chemopreventive, Chemotherapeutic, Kidney Cancer, Vitamin C: Intravenous

Arctigenin results in autophagic cell death and decreased ER expression in ER-positive human breast cancer cells.

Article Published Date : Feb 08, 2018
Study Type : In Vitro Study
Additional Links
Substances : Arctigenin : CK(160) : AC(107)
Diseases : Breast Cancer : CK(8278) : AC(3034)
Pharmacological Actions : Chemotherapeutic : CK(4337) : AC(1618)
Additional Keywords : Arctigenin, Breast Cancer : CK(113) : AC(34), Chemotherapeutic, Natural Substance/Drug Synergy : CK(1524) : AC(719)

Genistein intake mimicking Asian consumption patterns improved response of mammary tumors to tamoxifen therapy.

Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Genistein : CK(945) : AC(434)
Diseases : Breast Cancer : CK(8278) : AC(3034)
Pharmacological Actions : Chemotherapeutic : CK(4337) : AC(1618), Immunomodulatory : CK(6505) : AC(2354)
Additional Keywords : Breast Cancer : CK(113) : AC(34), Chemotherapeutic, Gene Expression Regulation : CK(1401) : AC(623), Genistein, Immunomodulatory

Iscador Qu inhibits doxorubicin-induced senescence of MCF7 cells.

Article Published Date : Jun 18, 2017
Study Type : In Vitro Study
Additional Links
Substances : Mistletoe : CK(243) : AC(61)
Diseases : Breast Cancer : CK(8278) : AC(3034)
Pharmacological Actions : Chemotherapeutic : CK(4337) : AC(1618)
Additional Keywords : Breast Cancer : CK(113) : AC(34), Chemotherapeutic, Chemotherapeutic Synergy: Doxorubicin : CK(343) : AC(264), Mistletoe

Low-molecular-weight fucoidan combined with chemotarget agents significantly improved the disease control rate.

Article Published Date : Apr 20, 2017
Study Type : Human Study
Additional Links
Substances : Fucoidan : CK(866) : AC(451)
Diseases : Colorectal Cancer : CK(4884) : AC(2273)
Pharmacological Actions : Chemotherapeutic : CK(4337) : AC(1618)
Additional Keywords : Chemotherapeutic, COLORECTAL CANCER, Fucoidan

Melatonin could be used as an adjuvant agent with rapamycin in head and neck cancers.

Article Published Date : Dec 15, 2017
Study Type : In Vitro Study
Additional Links
Substances : Melatonin : CK(2891) : AC(911)
Diseases : Head and Neck Cancer : CK(787) : AC(188)
Pharmacological Actions : Chemoprotective Agents : CK(4246) : AC(1618), Chemotherapeutic : CK(4337) : AC(1618)
Additional Keywords : Chemoprotective Agents, Chemotherapeutic, Head and Neck Cancer, melatonin, Natural Substance/Drug Synergy : CK(1524) : AC(719)

Neferine augments the therapeutic efficacy of cisplatin in human lung adenocarcinoma cells.

Article Published Date : Apr 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Lotus : CK(398) : AC(258)
Diseases : Lung Cancer : CK(3062) : AC(1428)
Pharmacological Actions : Autophagy Up-regulation : CK(836) : AC(558), Chemotherapeutic : CK(4337) : AC(1618)
Additional Keywords : Autophagy Up-regulation, Chemotherapeutic, Chemotherapeutic Synergy: Cisplatin : CK(430) : AC(339), Lotus, lung cancer

Neferine revealed higher toxicity toward paclitaxel and doxorubicin-resistant breast, lung or colon cancer cells.

Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Lotus : CK(398) : AC(258)
Diseases : Breast Cancer : CK(8278) : AC(3034), Cancers: Multi-Drug Resistant : CK(194) : AC(156), Colon Cancer : CK(1919) : AC(1202), Lung Cancer : CK(3062) : AC(1428)
Pharmacological Actions : Chemosensitizer : CK(1644) : AC(1266), Chemotherapeutic : CK(4337) : AC(1618)
Additional Keywords : Breast Cancer : CK(113) : AC(34), Cancers: Multi-Drug Resistant, Chemosensitizer, Chemotherapeutic, COLON CANCER, Lotus, lung cancer

Phytochemistry, pharmacology, and therapeutic uses of black seed (Nigella sativa).

Article Published Date : Sep 30, 2016
Study Type : Review
Additional Links
Substances : Nigella sativa (aka Black Seed) : CK(1912) : AC(494)
Pharmacological Actions : Analgesics : CK(9622) : AC(1463), Anti-Inflammatory Agents : CK(39493) : AC(15764), Anticonvulsants : CK(1005) : AC(272), Antihypertensive Agents : CK(6955) : AC(1013), Antimicrobial : CK(1576) : AC(789), Antioxidants : CK(34418) : AC(14437), Chemotherapeutic : CK(4337) : AC(1618), Hypoglycemic Agents : CK(8747) : AC(2035), Hypolipidemic : CK(8915) : AC(2013)
Additional Keywords : Analgesics, Anti-Inflammatory Agents, Anticonvulsants, Antihypertensive Agents, Antimicrobial, Antioxidants : CK(303) : AC(126), Chemotherapeutic, Nigella sativa (aka Black Seed), Plant Extracts : CK(18748) : AC(6773)

Structural optimization of mangiferin binding to cancer molecular targets.

Article Published Date : Mar 19, 2018
Study Type : In Vitro Study
Additional Links
Substances : Mangiferin : CK(376) : AC(223)
Diseases : Cancers: All : CK(36285) : AC(14319)
Pharmacological Actions : Chemotherapeutic : CK(4337) : AC(1618)
Additional Keywords : Cancers: All, Chemotherapeutic, Mangiferin

These results suggest fisetin in combination with gemcitabine as a candidate for use in improved anticancer regimens.

Article Published Date : Jan 10, 2016
Study Type : In Vitro Study
Additional Links
Substances : Fisetin : CK(441) : AC(275), Flavonoids : CK(4696) : AC(2174)
Diseases : Cholangiocarcinoma : CK(213) : AC(91)
Pharmacological Actions : Antiproliferative : CK(9975) : AC(7471), Apoptotic : CK(9570) : AC(7368), Chemotherapeutic : CK(4337) : AC(1618)
Additional Keywords : Antiproliferative : CK(75) : AC(61), Apoptotic, Chemotherapeutic, Chemotherapeutic Synergy: Gemcitabine : CK(115) : AC(83), Cholangiocarcinoma, Fisetin, Flavonoids

This study confirms the potential of modified pectin to improve chemotherapeutic cancer treatments.

Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Modified Citrus Pectin : CK(120) : AC(33)
Diseases : Liver Cancer : CK(3115) : AC(1639), Lung Cancer : CK(3062) : AC(1428)
Pharmacological Actions : Apoptotic : CK(9570) : AC(7368), Chemotherapeutic : CK(4337) : AC(1618)
Additional Keywords : Apoptotic, Chemotherapeutic, liver cancer, lung cancer, Modified Citrus Pectin

This study provides evidence that blueberries may be unique sources for anti-AML therapy.

Article Published Date : Dec 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Blueberry : CK(1151) : AC(334)
Diseases : Acute Myeloid Leukemia : CK(300) : AC(152)
Pharmacological Actions : Chemotherapeutic : CK(4337) : AC(1618)
Additional Keywords : Acute Myeloid Leukemia, Blueberry, Chemotherapeutic

Vitamin C with decitabine activates TET2 in leukemic cells and significantly improves overall survival in elderly patients with acute myeloid leukemia.

Article Published Date : Jan 01, 2018
Study Type : In Vitro Study
Additional Links
Substances : Vitamin C : CK(6065) : AC(1407), Vitamin C: Intravenous : CK(404) : AC(60)
Diseases : Acute Myeloid Leukemia : CK(300) : AC(152)
Pharmacological Actions : Antiproliferative : CK(9975) : AC(7471), Apoptotic : CK(9570) : AC(7368), Cell cycle arrest : CK(2120) : AC(1715), Chemotherapeutic : CK(4337) : AC(1618)
Additional Keywords : Acute Myeloid Leukemia, Antiproliferative : CK(75) : AC(61), Apoptotic, Cell cycle arrest, Chemotherapeutic, Natural Substance/Drug Synergy : CK(1524) : AC(719), Vitamin C : CK(48) : AC(13), Vitamin C: Intravenous

Vitamin K has been shown to suppress the growth of liver cancer cells.

Article Published Date : Oct 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Vitamin K2 : CK(560) : AC(91)
Diseases : Liver Cancer : CK(3115) : AC(1639)
Pharmacological Actions : Antineoplastic Agents : CK(2235) : AC(1468), Apoptotic : CK(9570) : AC(7368), Chemotherapeutic : CK(4337) : AC(1618)
Additional Keywords : Antineoplastic Agents : CK(78) : AC(35), Apoptotic, Chemotherapeutic, liver cancer, Natural Substance/Drug Synergy : CK(1524) : AC(719), Vitamin K2 : CK(16) : AC(6)

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