Results for Chemosensitizer

Andrographolide enhances cisplatin-mediated anticancer effects in lung cancer cells.

Article Published Date : Jul 06, 2017
Study Type : In Vitro Study
Additional Links
Substances : Andrographolide : CK(10) : AC(9)
Diseases : Lung Cancer : CK(2308) : AC(999)
Pharmacological Actions : Autophagy Inhibitors : CK(175) : AC(115), Chemosensitizer : CK(1124) : AC(854), Chemotherapeutic : CK(2328) : AC(1086)
Additional Keywords : Andrographolidem, Autophagy Inhibitors : CK(5) : AC(4), Chemosensitizer, Chemotherapeutic Synergy: Cisplatin : CK(290) : AC(232), lung cancer

Chemo-sensitization resulting from fasting may in fact be an effect of enhanced immune surveillance.

Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Diseases : Cancers: All : CK(28241) : AC(10590)
Therapeutic Actions : Fasting/Caloric Restriction : CK(449) : AC(108)
Pharmacological Actions : Chemosensitizer : CK(1124) : AC(854)
Additional Keywords : Cancer : CK(50) : AC(12), cancer cure, Chemosensitizer, Chemotherapy : CK(44) : AC(7), Fasting

Curcumin might be a potential adjuvant for non-small-cell lung cancer patients during Paclitaxel treatment.

Article Published Date : Mar 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(5598) : AC(2788)
Diseases : Carcinoma: Non-Small-Cell Lung : CK(264) : AC(161)
Pharmacological Actions : Chemosensitizer : CK(1124) : AC(854)
Additional Keywords : Carcinoma: Non-Small-Cell Lung, Chemosensitizer, Chemothapeutic Synergy: Paclitaxel : CK(109) : AC(85), CURCUMIN : CK(2) : AC(1)

Diallyl trisulfide suppresses tumor growth and potentiates cisplatin efficacy in gastric cancer treatment.

Article Published Date : Mar 26, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Dimethyl trisulfide (DMTS) : CK(8) : AC(5)
Diseases : Gastric Cancer : CK(1165) : AC(504)
Pharmacological Actions : Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348), Chemosensitizer : CK(1124) : AC(854)
Additional Keywords : Apoptotic, Cell cycle arrest, Chemosensitizer, Chemotherapeutic Synergy: Cisplatin : CK(290) : AC(232), Dimethyl trisulfide (DMTS), gastric cancer

Egyptian sweet orange hesperidin ameliorates the cytotoxic effect of doxorubicin while enhancing its anti-tumor effect.

Article Published Date : Mar 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Hesperidin : CK(545) : AC(215), Sweet Orange : CK(48) : AC(17)
Diseases : Ehrlich carcinoma : CK(17) : AC(9)
Pharmacological Actions : Chemoprotective Agents : CK(2322) : AC(906), Chemosensitizer : CK(1124) : AC(854)
Additional Keywords : Chemoprotective Agents, Chemosensitizer, Chemotherapeutic Synergy: Doxorubicin : CK(220) : AC(168), Ehrlich carcinoma, Hesperidin, Sweet Orange

Inhibition of pyruvate kinase M2 markedly reduces chemoresistance of advanced bladder cancer to cisplatin.

Article Published Date : Apr 04, 2017
Study Type : In Vitro Study
Additional Links
Substances : Shikonin : CK(108) : AC(63)
Diseases : Bladder Cancer : CK(632) : AC(247)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Chemosensitizer : CK(1124) : AC(854)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, bladder cancer, Chemosensitizer, Chemotherapeutic Synergy: Cisplatin : CK(290) : AC(232), Dose Response : CK(1712) : AC(683), Shikonin

Neferine enhances oxaliplatin sensitivity through an inhibition of EMT in liver cancer cells.

Article Published Date : Jan 29, 2017
Study Type : In Vitro Study
Additional Links
Substances : Lotus : CK(237) : AC(170)
Diseases : Liver Cancer : CK(2460) : AC(1189)
Pharmacological Actions : Chemosensitizer : CK(1124) : AC(854)
Additional Keywords : Chemosensitizer, Chemotherapeutic Synergy: Oxaliplatin : CK(12) : AC(9), liver cancer, Lotus

Neferine reduces the cisplatin dose requirement in cancer chemotherapy.

Article Published Date : Feb 17, 2017
Study Type : In Vitro Study
Additional Links
Substances : Lotus : CK(237) : AC(170)
Diseases : Lung Cancer : CK(2308) : AC(999)
Pharmacological Actions : Apoptotic : CK(6986) : AC(5304), Chemosensitizer : CK(1124) : AC(854), Vascular Endothelial Growth Factor Inhibitors : CK(435) : AC(247)
Additional Keywords : Apoptotic, Chemosensitizer, Chemotherapeutic Synergy: Cisplatin : CK(290) : AC(232), Lotus, lung cancer, Vascular Endothelial Growth Factor Inhibitors

Neferine revealed higher toxicity toward paclitaxel and doxorubicin-resistant breast, lung or colon cancer cells.

Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Lotus : CK(237) : AC(170)
Diseases : Breast Cancer : CK(6327) : AC(2272), Cancers: Multi-Drug Resistant : CK(178) : AC(143), Colon Cancer : CK(1493) : AC(954), Lung Cancer : CK(2308) : AC(999)
Pharmacological Actions : Chemosensitizer : CK(1124) : AC(854), Chemotherapeutic : CK(2328) : AC(1086)
Additional Keywords : Breast Cancer : CK(113) : AC(34), Cancers: Multi-Drug Resistant, Chemosensitizer, Chemotherapeutic, COLON CANCER, Lotus, lung cancer

Resveratrol prevents endothelial cells injury in high-dose interleukin-2 therapy against melanoma.

Article Published Date : Dec 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol : CK(2037) : AC(1112)
Diseases : Lung Cancer : CK(2308) : AC(999), Melanoma : CK(733) : AC(408)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481), Chemoprotective Agents : CK(2322) : AC(906), Chemosensitizer : CK(1124) : AC(854)
Additional Keywords : Anti-metastatic, Chemoprotective Agents, Chemosensitizer, lung cancer, melanoma, RESVERATROL

Sanguinarine sensitizes human gastric adenocarcinoma AGS cells to TRAIL-mediated apoptosis.

Article Published Date : Oct 31, 2009
Study Type : In Vitro Study
Additional Links
Substances : Bloodroot : CK(37) : AC(13)
Diseases : Gastric Cancer : CK(1165) : AC(504)
Pharmacological Actions : Apoptotic : CK(6986) : AC(5304), Caspase-3 Activation : CK(137) : AC(90), Chemosensitizer : CK(1124) : AC(854)
Additional Keywords : Apoptotic, Bloodroot, Caspase-3 Activation, Chemosensitizer, gastric cancer

Synergistic anti-breast-cancer effects of combined treatment with oleuropein and doxorubicin.

Article Published Date : Jun 22, 2017
Study Type : Animal Study
Additional Links
Substances : Oleuropein : CK(226) : AC(136)
Diseases : Breast Cancer : CK(6327) : AC(2272)
Pharmacological Actions : Chemosensitizer : CK(1124) : AC(854)
Additional Keywords : Breast Cancer : CK(113) : AC(34), Chemosensitizer, Chemotherapeutic Synergy: Doxorubicin : CK(220) : AC(168), Oleuropein

The combination of centchroman with genistein has selective cytotoxic effect for human breast cancer cell lines.

Article Published Date : Oct 31, 2016
Study Type : Human In Vitro
Additional Links
Substances : Genistein : CK(788) : AC(365)
Diseases : Breast Cancer : CK(6327) : AC(2272), Breast Cancer: Triple Negative : CK(708) : AC(466)
Pharmacological Actions : Chemosensitizer : CK(1124) : AC(854)
Additional Keywords : Breast Cancer : CK(113) : AC(34), Breast Cancer: Triple Negative, Chemosensitizer, Genistein, Natural Substance/Drug Synergy : CK(957) : AC(485), Selective Cytotoxicity : CK(264) : AC(195)

This review describes the role of antioxidants like sulforaphane and curcumin in combatting chemoresistance and chemotherapy-induced oxidative stress through NF-kappaB and HIF-1a inhibition.

Article Published Date : Jun 29, 2019
Study Type : Review
Additional Links
Substances : Broccoli Sprouts : CK(262) : AC(46), Curcumin : CK(5598) : AC(2788), Sulforaphane : CK(930) : AC(452), Turmeric : CK(7078) : AC(3169)
Pharmacological Actions : Anti Inflammatory, Antioxidant Effects : CK(15) : AC(4), Chemosensitizer : CK(1124) : AC(854), Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor : CK(214) : AC(142), NF-kappaB Inhibitor : CK(3536) : AC(2098), Nrf2 activation : CK(1584) : AC(916)
Additional Keywords : Anti-cancer, Chemoresistance : CK(6) : AC(5), Chemosensitizer, Chemotherapy : CK(44) : AC(7)
Problem Substances : Chemotherapy : CK(459) : AC(79)

Vitamin C and K can sensitize cancer cells to conventional chemotherapy.

Article Published Date : Mar 19, 2018
Study Type : Review
Additional Links
Substances : Vitamin C : CK(4687) : AC(1149), Vitamin K : CK(836) : AC(136)
Diseases : Cancers: All : CK(28241) : AC(10590)
Pharmacological Actions : Chemosensitizer : CK(1124) : AC(854)
Additional Keywords : Cancers: All, Chemosensitizer, Vitamin C : CK(1) : AC(1), Vitamin K

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