Results for Bisphenol Toxicity

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A high fat diet and a low-dose BPA exposure during pregnancy increases mammary tumor incidence in offspring.

Article Published Date : May 08, 2017
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4363) : AC(1306), Breast Cancer : CK(8185) : AC(3005), High Fat Diet : CK(2021) : AC(974)
Additional Keywords : Bisphenol A, Bisphenol Toxicity, Breast Cancer : CK(113) : AC(34), high fat diet, Increased Risk : CK(8703) : AC(1109), Transgenerational Epigenetic Modification : CK(241) : AC(91)
Problem Substances : Bisphenol A : CK(4552) : AC(1317)

Adolescent BPA exposure below the safe daily limit leads to alterations in some behaviours and neuronal morphology that endure into adulthood.

Article Published Date : Feb 28, 2015
Study Type : Animal Study
Additional Links
Diseases : Anxiety Disorders : CK(1556) : AC(240), Bisphenol Toxicity : CK(4363) : AC(1306)
Additional Keywords : Anxiety Disorders, Bisphenol A, Bisphenol Toxicity
Problem Substances : Bisphenol A : CK(4552) : AC(1317)

Bile acids and tryptophan metabolism are novel pathways involved in metabolic abnormalities in BPA-exposed pregnant mice and male offspring.

Article Published Date : May 24, 2017
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4363) : AC(1306), Fetal Origin of Adult Disease : CK(249) : AC(62)
Additional Keywords : Bisphenol A, Bisphenol Toxicity, Fetal Origin of Adult Disease
Problem Substances : Bisphenol A : CK(4552) : AC(1317)

Bisphenol A influences oestrogen and thyroid hormone-regulated thyroid hormone receptor expression.

Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4363) : AC(1306)
Additional Keywords : Bisphenol A, Bisphenol Toxicity, Risk Factors : CK(14797) : AC(2072), Thyroid
Problem Substances : Bisphenol A : CK(4552) : AC(1317)

Bisphenol A was detected above the detection limit in all samples in individuals affected by non-alcoholic fatty liver disease.

Article Published Date : Jun 04, 2017
Study Type : Human In Vitro, Human Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4363) : AC(1306), Chemically-Induced Liver Damage : CK(2271) : AC(1071)
Additional Keywords : Bisphenol A, Bisphenol Toxicity, Chemically-Induced Liver Damage
Problem Substances : Bisphenol A : CK(4552) : AC(1317)

BPA alternatives are not necessarily less estrogenic than BPA in human breast cancer cells.

Article Published Date : Jun 06, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4363) : AC(1306), Breast Cancer : CK(8185) : AC(3005)
Additional Keywords : Bisphenol A, Bisphenol AP, Bisphenol F, Bisphenol S, Bisphenol Toxicity, Breast Cancer : CK(113) : AC(34)
Problem Substances : Bisphenol A : CK(4552) : AC(1317), Bisphenol AP : CK(15) : AC(5), Bisphenol F : CK(390) : AC(108), Bisphenol S : CK(794) : AC(253)

BPA can promote the proliferation of thyroid carcinoma B-CPAP cells and decrease the apoptosis of cells.

Article Published Date : Jun 06, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4363) : AC(1306), Thyroid Cancer : CK(486) : AC(159)
Additional Keywords : Bisphenol A, Bisphenol Toxicity, Thyroid Cancer
Problem Substances : Bisphenol A : CK(4552) : AC(1317)

BPA exposure during the second trimester may have adverse effect on blood glucose levels among subfertile women.

Article Published Date : Mar 31, 2017
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4363) : AC(1306)
Additional Keywords : Bisphenol A, Bisphenol Toxicity, women's health
Problem Substances : Bisphenol A : CK(4552) : AC(1317)

BPA exposure has adverse effect on cardiac insulin signal transduction which may affect its function.

Article Published Date : Jan 29, 2017
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4363) : AC(1306)
Additional Keywords : Bisphenol A, Bisphenol Toxicity, Risk Factors : CK(14797) : AC(2072)
Problem Substances : Bisphenol A : CK(4552) : AC(1317)
Adverse Pharmacological Actions : Cardiotoxic : CK(1168) : AC(209)

BPA exposure was associated with alterations in the timing of pubertal development.

Article Published Date : Jul 26, 2017
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4363) : AC(1306), Puberty: Delayed : CK(36) : AC(5)
Additional Keywords : Bisphenol A, Bisphenol Toxicity, Puberty: Delayed
Problem Substances : Bisphenol A : CK(4552) : AC(1317)

BPA may play a major role in the pathogenesis of polycystic ovarian syndrome.

Article Published Date : Nov 30, 2017
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4363) : AC(1306), Polycystic Ovary Syndrome : CK(1929) : AC(310)
Additional Keywords : Bisphenol A, Bisphenol Toxicity, Increased Risk : CK(8703) : AC(1109), Polycystic Ovary Syndrome
Problem Substances : Bisphenol A : CK(4552) : AC(1317)

Crocin possesses hepatoprotective effects against BPA-induced liver toxicity.

Article Published Date : Jul 04, 2017
Study Type : Animal Study
Additional Links
Substances : Crocin : CK(731) : AC(310)
Diseases : Bisphenol Toxicity : CK(4363) : AC(1306)
Pharmacological Actions : Antioxidants : CK(34012) : AC(14225), Hepatoprotective : CK(8852) : AC(3772), MicroRNA modulator : CK(1557) : AC(895)
Additional Keywords : Antioxidants : CK(303) : AC(126), Bisphenol Toxicity, Crocin, Hepatoprotective, MicroRNA modulator
Problem Substances : Bisphenol A : CK(4552) : AC(1317)

Diet and BPA appear to modulate the activation of the AR pathway and thereby optimize tumor establishment in the gerbil prostate.

Article Published Date : Jan 31, 2018
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4363) : AC(1306), Prostate Cancer : CK(2772) : AC(1034)
Additional Keywords : Bisphenol A, Bisphenol Toxicity, Increased Risk : CK(8703) : AC(1109), prostate cancer
Problem Substances : Bisphenol A : CK(4552) : AC(1317)

Exposure to nonylphenol and BPA and possibly inflammation in increasing oxidative stress and decreasing antioxidant activity during pregnancy.

Article Published Date : May 10, 2017
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4363) : AC(1306), Inflammation : CK(15658) : AC(5321), Prenatal Chemical Exposures : CK(2428) : AC(530)
Additional Keywords : Bisphenol A, Bisphenol Toxicity, Inflammation : CK(128) : AC(57), Nonylphenol, Prenatal Chemical Exposures, Risk Factors : CK(14797) : AC(2072)
Problem Substances : Bisphenol A : CK(4552) : AC(1317), Nonylphenol : CK(12) : AC(7)

Higher maternal urinary BPS concentrations were associated with increased gestational age

Article Published Date : Apr 01, 2018
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4363) : AC(1306)
Additional Keywords : Bisphenol S, Bisphenol Toxicity
Problem Substances : Bisphenol S : CK(794) : AC(253)

Increased BPA concentration in the follicular fluid of polycystic ovary syndrome patients may play an important role in its pathogenesis.

Article Published Date : Dec 31, 2016
Study Type : Human In Vitro
Additional Links
Diseases : Bisphenol Toxicity : CK(4363) : AC(1306), Polycystic Ovary Syndrome : CK(1929) : AC(310)
Additional Keywords : Bisphenol A, Bisphenol Toxicity, Polycystic Ovary Syndrome
Problem Substances : Bisphenol A : CK(4552) : AC(1317)

Involvement of insulin signalling disturbances in bisphenol A-induced Alzheimer's disease-like neurotoxicity.

Article Published Date : Aug 07, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Alzheimer's Disease : CK(5252) : AC(2165), Bisphenol Toxicity : CK(4363) : AC(1306)
Additional Keywords : Alzheimer's disease, Bisphenol A, Bisphenol Toxicity
Problem Substances : Bisphenol A : CK(4552) : AC(1317)

Low concentrations of bisphenol A promote human ovarian cancer cell proliferation.

Article Published Date : Sep 30, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4363) : AC(1306), Ovarian Cancer : CK(1021) : AC(503)
Additional Keywords : Bisphenol A, Bisphenol Toxicity, ovarian cancer
Problem Substances : Bisphenol A : CK(4552) : AC(1317)

Low-dose exposure to bisphenols A, F and S of human primary adipocyte impacts coding and non-coding RNA profiles.

Article Published Date : Dec 31, 2016
Study Type : Human In Vitro
Additional Links
Diseases : Bisphenol Toxicity : CK(4363) : AC(1306)
Additional Keywords : Bisphenol A, Bisphenol F, Bisphenol S, Bisphenol Toxicity
Problem Substances : Bisphenol A : CK(4552) : AC(1317), Bisphenol F : CK(390) : AC(108), Bisphenol S : CK(794) : AC(253)

Lung injury induced by bisphenol A is ameliorated by selenium supplementation.

Article Published Date : Feb 11, 2017
Study Type : Animal Study
Additional Links
Substances : Selenium : CK(1750) : AC(391)
Diseases : Bisphenol Toxicity : CK(4363) : AC(1306), Fibrosis : CK(373) : AC(179), Lung Damage : CK(403) : AC(173)
Pharmacological Actions : Anti-Fibrotic : CK(2167) : AC(1028), Anti-Inflammatory Agents : CK(38674) : AC(15430), Antioxidants : CK(34012) : AC(14225)
Additional Keywords : Anti-Fibrotic, Anti-Inflammatory Agents, Antioxidants : CK(303) : AC(126), Bisphenol Toxicity, Fibrosis, Lung Damage, Selenium : CK(3) : AC(2)
Problem Substances : Bisphenol A : CK(4552) : AC(1317)

Maternal folate supplementation counteracts bisphenol A induced Igf2 DNA hypermethylation in the offspring.

Article Published Date : Feb 05, 2017
Study Type : Animal Study
Additional Links
Substances : Folate : CK(422) : AC(66), Folate: Dietary : CK(106) : AC(13)
Diseases : Bisphenol Toxicity : CK(4363) : AC(1306), Prenatal Chemical Exposures : CK(2428) : AC(530)
Pharmacological Actions : Pancreato Protective Agents : CK(535) : AC(293)
Additional Keywords : Bisphenol A, Bisphenol Toxicity, Folate : CK(8) : AC(3), Prenatal Chemical Exposures, Risk Reduction : CK(17881) : AC(1997)
Problem Substances : Bisphenol A : CK(4552) : AC(1317)

Prenatal exposure to BPA may potentially increase the risk of allergic diseases at very early life in female infants.

Article Published Date : Jan 30, 2017
Study Type : Human Study
Additional Links
Diseases : Allergies : CK(1736) : AC(374), Bisphenol Toxicity : CK(4363) : AC(1306), Prenatal Chemical Exposures : CK(2428) : AC(530)
Additional Keywords : allergies, Bisphenol Toxicity, Increased Risk : CK(8703) : AC(1109), Prenatal Chemical Exposures
Problem Substances : Bisphenol A : CK(4552) : AC(1317)

Similar to BPA, chronic treatment of cells with DMBPA resulted in enhancement of anchorage-independent growth.

Article Published Date : Dec 19, 2016
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4363) : AC(1306), Prostate Cancer : CK(2772) : AC(1034)
Additional Keywords : Bisphenol A, Bisphenol Toxicity, BPA, prostate cancer, Risk Factors : CK(14797) : AC(2072)
Problem Substances : Bisphenol A : CK(4552) : AC(1317)

The presence of nanoplastics can increase BPA bioavailability and cause neurotoxicity in adult zebrafish.

Article Published Date : Aug 04, 2017
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4363) : AC(1306)
Additional Keywords : Bisphenol A, Bisphenol Toxicity
Problem Substances : Bisphenol A : CK(4552) : AC(1317)
Adverse Pharmacological Actions : Neurotoxic : CK(2838) : AC(702)

These findings probably suggest that BPA exposure induces inflammation and exacerbates tumorigenesis.

Article Published Date : Sep 30, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4363) : AC(1306), Cancers: All : CK(35914) : AC(14179), Inflammation : CK(15658) : AC(5321)
Additional Keywords : Bisphenol A, Bisphenol Toxicity, Cancers: All, Inflammation : CK(128) : AC(57), Risk Factors : CK(14797) : AC(2072)
Problem Substances : Bisphenol A : CK(4552) : AC(1317)
Adverse Pharmacological Actions : Inflammatory : CK(541) : AC(169)

This study provides ANXA6 and VCP as proteomic biomarkers for BPA in early life exposure and their potential for women's thyroid cancer.

Article Published Date : Mar 07, 2017
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity : CK(4363) : AC(1306), Thyroid Cancer : CK(486) : AC(159)
Additional Keywords : Bisphenol A, Bisphenol Toxicity, Risk Factors : CK(14797) : AC(2072), Thyroid Cancer
Problem Substances : Bisphenol A : CK(4552) : AC(1317)

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