Results for Apoptotic

A comprehensive review on anticancer mechanisms of crocin.

Article Published Date : Jul 02, 2017
Study Type : Review
Additional Links
Substances : Crocin : CK(391) : AC(184)
Diseases : Cancers: All : CK(28241) : AC(10590)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481), Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Chemotherapeutic : CK(2328) : AC(1086), Telomerase Inhibitor : CK(95) : AC(62)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(65) : AC(52), Apoptotic, Cancers: All, Chemotherapeutic, Crocin, Telomerase Inhibitor

A wasabi extract exhibits anti-colon cancer properties through the induction of apoptosis and autophagy.

Article Published Date : Feb 29, 2016
Study Type : In Vitro Study
Additional Links
Substances : Wasabi : CK(24) : AC(19)
Diseases : Colon Cancer : CK(1493) : AC(954)
Pharmacological Actions : Apoptotic : CK(6986) : AC(5304), Autophagy Up-regulation : CK(518) : AC(349)
Additional Keywords : Apoptotic, Autophagy Up-regulation, COLON CANCER, Plant Extracts : CK(14140) : AC(5210), Wasabi

A water-soluble polysaccharide is able to reduce the number of fat cells and the mass of adipose tissue.

Article Published Date : Jul 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : White Mulberry : CK(140) : AC(54)
Diseases : Obesity : CK(6879) : AC(1686)
Pharmacological Actions : Apoptotic : CK(6986) : AC(5304)
Additional Keywords : Anti-Obesity Agents : CK(2925) : AC(774), Apoptotic, obesity, Plant Extracts : CK(14140) : AC(5210), Polysaccharides : CK(625) : AC(392), White Mulberry

Alkaloids from Peganum harmala could be a promising candidate for the therapy of leukemia.

Article Published Date : Nov 02, 2015
Study Type : In Vitro Study
Additional Links
Substances : Syrian rue : CK(1) : AC(1)
Diseases : Leukemia : CK(1709) : AC(739)
Pharmacological Actions : Apoptotic : CK(6986) : AC(5304)
Additional Keywords : Apoptotic, leukemia, Syrian rue

An extract of Litchi seed has potential for development into a safe and potent alternative therapy for prostate cancer patients.

Article Published Date : Jan 29, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Litchi : CK(29) : AC(17)
Diseases : Prostate Cancer : CK(2407) : AC(834)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481), Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348), P21 Activation : CK(160) : AC(119)
Additional Keywords : Anti-metastatic, Apoptotic, Cell cycle arrest, Litchi, P21 Activation, Plant Extracts : CK(14140) : AC(5210), prostate cancer

An extract of Lotus may be a powerful agent against colon cancer cells.

Article Published Date : Feb 28, 2017
Study Type : In Vitro Study
Additional Links
Substances : Lotus : CK(237) : AC(170)
Diseases : Colon Cancer : CK(1493) : AC(954)
Pharmacological Actions : Apoptotic : CK(6986) : AC(5304), Bcl-2 protein down-regulation : CK(553) : AC(407), Bcl-xL down-regulation : CK(35) : AC(26), Cyclooxygenase 2 Inhibitors : CK(1589) : AC(926), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(727) : AC(442), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(786) : AC(505), NF-kappaB Inhibitor : CK(3536) : AC(2098)
Additional Keywords : Apoptotic, Bcl-2 protein down-regulation, COLON CANCER, Lotus, Plant Extracts : CK(14140) : AC(5210)

Anti-cancerous effect of Inonotus taiwanensis polysaccharide extract on human acute monocytic leukemia cells.

Article Published Date : Jan 28, 2018
Study Type : In Vitro Study
Additional Links
Substances : Medicinal Mushrooms : CK(1715) : AC(797)
Diseases : Leukemia: Monocytic : CK(32) : AC(12)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Autophagy Inhibitors : CK(175) : AC(115)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Autophagy Inhibitors : CK(5) : AC(4), Leukemia: Monocytic, Medicinal Mushrooms, Polysaccharides : CK(625) : AC(392)

Apigenin induces the apoptosis of colon cancer cells.

Article Published Date : Mar 06, 2018
Study Type : In Vitro Study
Additional Links
Substances : Apigenin : CK(432) : AC(251)
Diseases : Colon Cancer : CK(1493) : AC(954)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Bcl-xL down-regulation : CK(35) : AC(26)
Additional Keywords : Antiproliferative : CK(65) : AC(52), APIGENIN, Apoptotic, Bcl-xL down-regulation, COLON CANCER

Avocado defensin could induce intrinsic apoptosis in breast cancer cells.

Article Published Date : Jul 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Avocado : CK(141) : AC(41)
Diseases : Breast Cancer : CK(6327) : AC(2272)
Pharmacological Actions : Apoptotic : CK(6986) : AC(5304), Caspase-7 Activation : CK(9) : AC(7), Caspase-9 Activation : CK(70) : AC(46)
Additional Keywords : Apoptotic, Avocado, Breast Cancer : CK(113) : AC(34), Caspase-7 Activation, Caspase-9 Activation

Baicalein induces cancer cell apoptosis and cause cell cycle arrest.

Article Published Date : Jul 31, 2016
Study Type : Review
Additional Links
Substances : Baicalein : CK(184) : AC(112)
Diseases : Cancers: All : CK(28241) : AC(10590)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Baicalein, Cancer : CK(50) : AC(12), Cell cycle arrest

Butyrate induced apoptosis and inhibited cell proliferation via enhancing the intracellular expression of miR-22.

Article Published Date : Mar 06, 2017
Study Type : In Vitro Study
Additional Links
Substances : Butyrate : CK(53) : AC(34)
Diseases : Liver Cancer : CK(2460) : AC(1189)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Histone deacetylase inhibitor : CK(98) : AC(69), MicroRNA modulator : CK(1023) : AC(618)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Butyrate, Histone deacetylase inhibitor, liver cancer, MicroRNA modulator

Caffeic acid and caffeic acid phenethyl ester induce apoptosis and cell cycle arrest of breast cancer cells MDA-MB-231.

Article Published Date : Sep 14, 2017
Study Type : In Vitro Study
Additional Links
Substances : Caffeic Acid : CK(96) : AC(61), Caffeic acid phenethyl ester : CK(172) : AC(99)
Diseases : Breast Cancer: Triple Negative : CK(708) : AC(466)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Breast Cancer: Triple Negative, Caffeic Acid, Caffeic acid phenethyl ester, Cell cycle arrest

Carnosic acid cooperates with tamoxifen to induce apoptosis in breast cancer cells.

Article Published Date : Apr 30, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carnosic Acid : CK(121) : AC(82)
Diseases : Breast Cancer : CK(6327) : AC(2272)
Pharmacological Actions : Apoptotic : CK(6986) : AC(5304), Bcl-2 protein down-regulation : CK(553) : AC(407), Bcl-xL down-regulation : CK(35) : AC(26)
Additional Keywords : Apoptotic, Bcl-2 protein down-regulation, Bcl-xL down-regulation, Breast Cancer : CK(113) : AC(34), Carnosic Acid, Synergy with Tamoxifen : CK(6) : AC(5)
Problem Substances : Tamoxifen : CK(401) : AC(68)

Carnosic acid induces apoptosis of hepatocellular carcinoma cells.

Article Published Date : Oct 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carnosic Acid : CK(121) : AC(82)
Diseases : Liver Cancer : CK(2460) : AC(1189)
Pharmacological Actions : Antineoplastic Agents : CK(1847) : AC(1170), Apoptotic : CK(6986) : AC(5304)
Additional Keywords : Antineoplastic Agents : CK(78) : AC(35), Apoptotic, Carnosic Acid, liver cancer

Cinnamon extract from Sanyangxuedai may be effective for treating leukemia.

Article Published Date : Aug 18, 2016
Study Type : In Vitro Study
Additional Links
Substances : Cinnamon : CK(406) : AC(150)
Diseases : Leukemia : CK(1709) : AC(739)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Cell cycle arrest, cinnamon, leukemia, Plant Extracts : CK(14140) : AC(5210)

Combination therapy with low concentrations of sorafenib and betulinic acid had the capacity to induce high levels of cell death.

Article Published Date : Oct 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Betulinic acid : CK(28) : AC(18)
Diseases : Carcinoma: Non-Small-Cell Lung : CK(264) : AC(161)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Betulinic acid, Carcinoma: Non-Small-Cell Lung, Natural Substance/Drug Synergy : CK(957) : AC(485)

Combined use of lower concentrations of jerantinine A and γ-tocotrienol induced potent cytotoxic effects on U87MG cancer cells.

Article Published Date : Jun 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Vitamin E: Gamma-tocotrienol : CK(51) : AC(33)
Diseases : Glioblastoma : CK(545) : AC(272)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348), Chemoprotective Agents : CK(2322) : AC(906), Chemosensitizer : CK(1124) : AC(854), Chemotherapeutic : CK(2328) : AC(1086), Tumor Suppressor Protein p53 Upregulation : CK(585) : AC(431)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Cell cycle arrest, Glioblastoma, Natural Substance/Drug Synergy : CK(957) : AC(485), Vitamin E: Gamma-tocotrienol

Cucurbitacin E may delay cancer cell growth by apoptosis via upregulation of DR5 gene expression.

Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Cucurbitacin E : CK(14) : AC(13)
Diseases : Cervical Cancer : CK(756) : AC(422)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Cervical Cancer, Cucurbitacin E, Gene Expression Regulation : CK(1141) : AC(501)

Curcumin exerts its tumor suppressive function via inhibition of NEDD4 oncoprotein in glioma cancer cells.

Article Published Date : Jun 07, 2017
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(5598) : AC(2788)
Diseases : Glioma : CK(588) : AC(251)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481), Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(65) : AC(52), Apoptotic, CURCUMIN : CK(2) : AC(1), Glioma

Curcumin induced leukemic cell apoptosis via an IFIT2-dependent signalling pathways.

Article Published Date : Jan 01, 2017
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(5598) : AC(2788)
Diseases : Leukemia : CK(1709) : AC(739)
Pharmacological Actions : Apoptotic : CK(6986) : AC(5304)
Additional Keywords : Apoptotic, CURCUMIN : CK(2) : AC(1), leukemia

Curcumin may serve as a promising anticancer agent by inducing a chronic ER stress mediated cell death and activation of cell cycle arrest.

Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(5598) : AC(2788)
Diseases : Prostate Cancer : CK(2407) : AC(834)
Pharmacological Actions : Apoptotic : CK(6986) : AC(5304)
Additional Keywords : Apoptotic, CURCUMIN : CK(2) : AC(1), prostate cancer

Diallyl trisulfide suppresses tumor growth and potentiates cisplatin efficacy in gastric cancer treatment.

Article Published Date : Mar 26, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Dimethyl trisulfide (DMTS) : CK(8) : AC(5)
Diseases : Gastric Cancer : CK(1165) : AC(504)
Pharmacological Actions : Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348), Chemosensitizer : CK(1124) : AC(854)
Additional Keywords : Apoptotic, Cell cycle arrest, Chemosensitizer, Chemotherapeutic Synergy: Cisplatin : CK(290) : AC(232), Dimethyl trisulfide (DMTS), gastric cancer

Effects of thymol on human gastric adenocarcinoma cells in vitro.

Article Published Date : Feb 23, 2018
Study Type : In Vitro Study
Additional Links
Substances : Thymol : CK(96) : AC(68)
Diseases : Gastric Cancer : CK(1165) : AC(504)
Pharmacological Actions : Apoptotic : CK(6986) : AC(5304)
Additional Keywords : Apoptotic, gastric cancer, Thymol

EGCG is effective in decreasing cell viability, apoptosis induction and enhancement of caspase 3 and Fas expression level in jurkat cells.

Article Published Date : Mar 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : EGCG (Epigallocatechin gallate) : CK(1091) : AC(605)
Diseases : Leukemia: T-cell acute Lymphoblastic : CK(27) : AC(17)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, EGCG (Epigallocatechin gallate), Leukemia: T-cell acute Lymphoblastic

Ethanol extract of Antrodia camphorata inhibits proliferation of HCT-8 human colorectal cancer cells.

Article Published Date : Sep 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Antrodia camphorata : CK(52) : AC(33)
Diseases : Colorectal Cancer : CK(3666) : AC(1651)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Antrodia camphorata, Apoptotic, Cell cycle arrest, COLORECTAL CANCER

Extracts of Parmelia sulcata and Usnea filipendula induced apoptosis-like cell death by causing DNA damage, to cancer cells.

Article Published Date : Sep 30, 2014
Study Type : In Vitro Study
Additional Links
Substances : Lichens : CK(72) : AC(49)
Diseases : Glioma : CK(588) : AC(251), Liver Cancer : CK(2460) : AC(1189), Lung Cancer : CK(2308) : AC(999)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Dose Response : CK(1712) : AC(683), Glioma, Lichens, liver cancer, lung cancer, Parmelia sulcata, Plant Extracts : CK(14140) : AC(5210)

Forced inhibition of PDE1A expression might be a new therapeutic strategy for the management of acute lymphoblastic leukemia.

Article Published Date : Dec 31, 2010
Study Type : In Vitro Study
Additional Links
Substances : Thymoquinone : CK(774) : AC(451)
Diseases : Acute lymphoblastic leukemia (ALL) : CK(193) : AC(72)
Pharmacological Actions : Antineoplastic Agents : CK(1847) : AC(1170), Apoptotic : CK(6986) : AC(5304)
Additional Keywords : Acute lymphoblastic leukemia (ALL), Antineoplastic Agents : CK(78) : AC(35), Apoptotic, thymoquinone

Fucoidan inhibited cell growth, induced apoptosis and suppressed angiogenesis in thyroid cancer cells.

Article Published Date : Apr 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Fucoidan : CK(401) : AC(228)
Diseases : Thyroid Cancer : CK(385) : AC(117)
Pharmacological Actions : Angiogenesis Inhibitors : CK(488) : AC(296), Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304)
Additional Keywords : Angiogenesis Inhibitors, Antiproliferative : CK(65) : AC(52), Apoptotic, Dose Response : CK(1712) : AC(683), Fucoidan, Thyroid Cancer

Gallic acid remarkably ameliorated the destabilization of liver tissue architecture caused by N-nitrosodiethylamine.

Article Published Date : May 31, 2017
Study Type : Animal Study
Additional Links
Substances : Gallic Acid : CK(157) : AC(93)
Diseases : Liver Cancer : CK(2460) : AC(1189)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Anticarcinogenic Agents : CK(1890) : AC(889), Antioxidants : CK(21528) : AC(8856), Apoptotic : CK(6986) : AC(5304), Chemopreventive : CK(5374) : AC(1717)
Additional Keywords : Anti-Inflammatory Agents, Anticarcinogenic Agents, Antioxidants : CK(303) : AC(126), Apoptotic, Chemopreventive, Gallic Acid, liver cancer
Problem Substances : N-nitrosodiethylamine : CK(2) : AC(1)

Gamma-tocotrienol profoundly alters sphingolipids in cancer cells.

Article Published Date : Apr 11, 2017
Study Type : In Vitro Study
Additional Links
Substances : Vitamin E: Gamma-tocotrienol : CK(51) : AC(33)
Diseases : Cancers: All : CK(28241) : AC(10590)
Pharmacological Actions : Apoptotic : CK(6986) : AC(5304), Autophagy Up-regulation : CK(518) : AC(349)
Additional Keywords : Apoptotic, Autophagy Up-regulation, Cancers: All, Vitamin E: Gamma-tocotrienol

Ganoderma lucidum triterpenes induce apoptosis in MCF-7 cells and attenuate DMBA induced mammary and skin carcinomas.

Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Reishi Mushroom : CK(406) : AC(202)
Diseases : Breast Cancer : CK(6327) : AC(2272), Skin Cancer : CK(1429) : AC(636)
Pharmacological Actions : Anticarcinogenic Agents : CK(1890) : AC(889), Apoptotic : CK(6986) : AC(5304), Bcl-2 protein down-regulation : CK(553) : AC(407), Bcl-xL down-regulation : CK(35) : AC(26), Chemopreventive : CK(5374) : AC(1717), Cyclin D1 Down-Regulation : CK(106) : AC(79)
Additional Keywords : Anticarcinogenic Agents, Apoptotic, Bcl-2 protein down-regulation, Bcl-xL down-regulation, Breast Cancer : CK(113) : AC(34), Chemopreventive, Cyclin D1 Down-Regulation, Reishi Mushroom, skin cancer

Garcinone E exerts anticancer activities by inducing apoptosis and suppressing migration and invasion in ovarian cancer cells.

Article Published Date : Sep 05, 2017
Study Type : In Vitro Study
Additional Links
Substances : Garcinia Mangostana : CK(9) : AC(1)
Diseases : Ovarian Cancer : CK(827) : AC(371)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481), Apoptotic : CK(6986) : AC(5304), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(727) : AC(442), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(786) : AC(505)
Additional Keywords : Anti-metastatic, Apoptotic, Garcinia Mangostana, ovarian cancer

Genistein treatment significantly suppressed proliferation and anchorage-independent growth of the human retinoblastoma cell line Y79 in vitro.

Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Genistein : CK(788) : AC(365)
Diseases : Retinoblastoma : CK(69) : AC(28)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), MicroRNA modulator : CK(1023) : AC(618)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Genistein, MicroRNA modulator, Retinoblastoma

Harmaline induces cell cycle arrest and apoptosis in SGC-7901 cells.

Article Published Date : Dec 17, 2015
Study Type : Animal Study
Additional Links
Substances : Syrian rue : CK(1) : AC(1)
Diseases : Gastric Cancer : CK(1165) : AC(504)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Cell cycle arrest, gastric cancer, Syrian rue

Harmine might be a potent inducer of apoptosis and autophagy in gastric carcinoma.

Article Published Date : May 14, 2017
Study Type : In Vitro Study
Additional Links
Substances : Syrian rue : CK(1) : AC(1)
Diseases : Gastric Cancer : CK(1165) : AC(504)
Pharmacological Actions : Apoptotic : CK(6986) : AC(5304), Autophagy Up-regulation : CK(518) : AC(349)
Additional Keywords : Apoptotic, Autophagy Up-regulation, gastric cancer, Syrian rue

Honokiol is a good candidate for further studies as a possible treatment for malignant melanoma.

Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Honokiol : CK(260) : AC(168)
Diseases : Malignant Melanoma : CK(87) : AC(38)
Pharmacological Actions : Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348)
Additional Keywords : Apoptotic, Cell cycle arrest, Honokiol, Malignant Melanoma

Inhibition of pyruvate kinase M2 markedly reduces chemoresistance of advanced bladder cancer to cisplatin.

Article Published Date : Apr 04, 2017
Study Type : In Vitro Study
Additional Links
Substances : Shikonin : CK(108) : AC(63)
Diseases : Bladder Cancer : CK(632) : AC(247)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Chemosensitizer : CK(1124) : AC(854)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, bladder cancer, Chemosensitizer, Chemotherapeutic Synergy: Cisplatin : CK(290) : AC(232), Dose Response : CK(1712) : AC(683), Shikonin

Neferine enhances the antitumor effect of mitomycin-c in hela cells.

Article Published Date : Mar 21, 2017
Study Type : In Vitro Study
Additional Links
Substances : Lotus : CK(237) : AC(170)
Diseases : Cervical Cancer : CK(756) : AC(422)
Pharmacological Actions : Apoptotic : CK(6986) : AC(5304)
Additional Keywords : Apoptotic, Cervical Cancer, Chemotherapeutic Synergy: Mitomycin C : CK(7) : AC(6), Lotus

Neferine reduces the cisplatin dose requirement in cancer chemotherapy.

Article Published Date : Feb 17, 2017
Study Type : In Vitro Study
Additional Links
Substances : Lotus : CK(237) : AC(170)
Diseases : Lung Cancer : CK(2308) : AC(999)
Pharmacological Actions : Apoptotic : CK(6986) : AC(5304), Chemosensitizer : CK(1124) : AC(854), Vascular Endothelial Growth Factor Inhibitors : CK(435) : AC(247)
Additional Keywords : Apoptotic, Chemosensitizer, Chemotherapeutic Synergy: Cisplatin : CK(290) : AC(232), Lotus, lung cancer, Vascular Endothelial Growth Factor Inhibitors

P. sulcata inhibited the growth in a dose-dependent manner and induced caspase-independent apoptosis at low doses.

Article Published Date : Apr 30, 2015
Study Type : Human In Vitro
Additional Links
Substances : Lichens : CK(72) : AC(49)
Diseases : Breast Cancer : CK(6327) : AC(2272), Breast Cancer: Triple Negative : CK(708) : AC(466)
Pharmacological Actions : Apoptotic : CK(6986) : AC(5304), Caspase-3 Activation : CK(137) : AC(90)
Additional Keywords : Apoptotic, Breast Cancer : CK(113) : AC(34), Breast Cancer: Triple Negative, Caspase-3 Activation, Dose Response : CK(1712) : AC(683), Lichens

Peganum harmala's extract decreases the growth rate of the cancer cell line through inducing apoptosis.

Article Published Date : Nov 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Syrian rue : CK(1) : AC(1)
Diseases : Breast Cancer : CK(6327) : AC(2272), Breast Cancer: Triple Negative : CK(708) : AC(466)
Pharmacological Actions : Apoptotic : CK(6986) : AC(5304)
Additional Keywords : Apoptotic, Breast Cancer : CK(113) : AC(34), Breast Cancer: Triple Negative, Syrian rue

Piperine is a promising candidate for targeting G-quadruplex DNA.

Article Published Date : Dec 19, 2016
Study Type : In Vitro Study
Additional Links
Substances : Piperine : CK(320) : AC(159)
Diseases : Lung Cancer : CK(2308) : AC(999)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, lung cancer, Piperine

Polysaccharide from Pleurotus nebrodensis induces apoptosis via a mitochondrial pathway in HepG2 cells.

Article Published Date : Dec 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Pleurotus nebrodensis : CK(3) : AC(2)
Diseases : DNA damage : CK(1997) : AC(713)
Pharmacological Actions : Antineoplastic Agents : CK(1847) : AC(1170), Apoptotic : CK(6986) : AC(5304)
Additional Keywords : Antineoplastic Agents : CK(78) : AC(35), Apoptotic, DNA damage, Pleurotus nebrodensis, Polysaccharides : CK(625) : AC(392)

Quercetrin from Toona sinensis leaves induces cell cycle arrest and apoptosis in human colorectal cancer SW620 cells.

Article Published Date : Nov 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Quercetin : CK(1179) : AC(590), Toona sinensis : CK(40) : AC(25)
Diseases : Colorectal Cancer : CK(3666) : AC(1651)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, COLORECTAL CANCER, QUERCETIN, Toona sinensis

Sanguinarine sensitizes human gastric adenocarcinoma AGS cells to TRAIL-mediated apoptosis.

Article Published Date : Oct 31, 2009
Study Type : In Vitro Study
Additional Links
Substances : Bloodroot : CK(37) : AC(13)
Diseases : Gastric Cancer : CK(1165) : AC(504)
Pharmacological Actions : Apoptotic : CK(6986) : AC(5304), Caspase-3 Activation : CK(137) : AC(90), Chemosensitizer : CK(1124) : AC(854)
Additional Keywords : Apoptotic, Bloodroot, Caspase-3 Activation, Chemosensitizer, gastric cancer

Sulforaphane alone or in combination with other therapies may be potentially useful for glioblastoma therapy.

Article Published Date : Jan 05, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Sulforaphane : CK(930) : AC(452)
Diseases : Glioblastoma : CK(545) : AC(272)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Cancer Stem Cells : CK(375) : AC(276), glioblastoma (GBM), Sulforaphane

Tangeretin may be a therapeutic agent for glioblastoma treatment.

Article Published Date : Jun 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Tangeretin : CK(38) : AC(24)
Diseases : Glioblastoma : CK(545) : AC(272)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Cell cycle arrest, Glioblastoma, Tangeretin

Tea polyphenols induce S phase arrest and apoptosis in gallbladder cancer cells.

Article Published Date : Feb 28, 2018
Study Type : Animal Study
Additional Links
Substances : Polyphenols : CK(1878) : AC(700)
Diseases : Gallbladder Cancer : CK(96) : AC(29)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Cell cycle arrest : CK(1678) : AC(1348)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Cell cycle arrest, Gallbladder Cancer, POLYPHENOLS : CK(1) : AC(1)

These findings indicate that mangiferin effectively inhibits cell growth and induces apoptosis of gastric cancer cells.

Article Published Date : Dec 04, 2017
Study Type : In Vitro Study
Additional Links
Substances : Mangiferin : CK(268) : AC(158)
Diseases : Gastric Cancer : CK(1165) : AC(504)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Dose Response : CK(1712) : AC(683), gastric cancer, Mangiferin

These results indicate a chemopreventive potential of in vitro fermented hazelnuts.

Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Fermented Foods and Beverages : CK(2588) : AC(607), Hazelnut : CK(46) : AC(8)
Diseases : Colon Cancer : CK(1493) : AC(954), DNA damage : CK(1997) : AC(713)
Pharmacological Actions : Anticarcinogenic Agents : CK(1890) : AC(889), Antineoplastic Agents : CK(1847) : AC(1170), Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304)
Additional Keywords : Anticarcinogenic Agents, Antineoplastic Agents : CK(78) : AC(35), Antiproliferative : CK(65) : AC(52), Apoptotic, COLON CANCER, DNA damage, Fermented Foods and Beverages, Hazelnut

Connect with GreenMedInfo

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2023 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.