Results for Anti-metastatic

A comprehensive review on anticancer mechanisms of crocin.

Article Published Date : Jul 02, 2017
Study Type : Review
Additional Links
Substances : Crocin : CK(745) : AC(319)
Diseases : Cancers: All : CK(37453) : AC(14904)
Pharmacological Actions : Anti-metastatic : CK(3007) : AC(2281), Antiproliferative : CK(10597) : AC(7939), Apoptotic : CK(10028) : AC(7756), Chemotherapeutic : CK(4518) : AC(1678), Telomerase Inhibitor : CK(101) : AC(68)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Apoptotic, Cancers: All, Chemotherapeutic, Crocin, Telomerase Inhibitor

A polysaccharide from Punica granatum has an inhibitory effect on metastasis.

Article Published Date : May 24, 2017
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1828) : AC(580)
Diseases : Cancer Metastasis : CK(986) : AC(559), Lung Cancer: Metastatic : CK(54) : AC(22)
Pharmacological Actions : Anti-metastatic : CK(3007) : AC(2281)
Additional Keywords : Anti-metastatic, Cancer Metastasis, Lung Cancer: Metastatic, pomegranate

A review of the multiple targets and signalling pathways of ginsenosides in cancers.

Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Ginsenosides : CK(2648) : AC(1456)
Diseases : Cancers: All : CK(37453) : AC(14904)
Pharmacological Actions : Anti-Inflammatory Agents : CK(42432) : AC(16960), Anti-metastatic : CK(3007) : AC(2281), Antiproliferative : CK(10597) : AC(7939), Cell cycle arrest : CK(2198) : AC(1786)
Additional Keywords : Anti-Inflammatory Agents, Anti-metastatic, Antiproliferative : CK(75) : AC(61), Cancers: All, Cell cycle arrest, Ginsenosides

An extract of Litchi seed has potential for development into a safe and potent alternative therapy for prostate cancer patients.

Article Published Date : Jan 29, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Litchi : CK(36) : AC(24)
Diseases : Prostate Cancer : CK(2886) : AC(1084)
Pharmacological Actions : Anti-metastatic : CK(3007) : AC(2281), Apoptotic : CK(10028) : AC(7756), Cell cycle arrest : CK(2198) : AC(1786), P21 Activation : CK(212) : AC(148)
Additional Keywords : Anti-metastatic, Apoptotic, Cell cycle arrest, Litchi, P21 Activation, Plant Extracts : CK(19328) : AC(7074), prostate cancer

Curcumin exerts its tumor suppressive function via inhibition of NEDD4 oncoprotein in glioma cancer cells.

Article Published Date : Jun 07, 2017
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(8658) : AC(3792)
Diseases : Glioma : CK(697) : AC(326)
Pharmacological Actions : Anti-metastatic : CK(3007) : AC(2281), Antiproliferative : CK(10597) : AC(7939), Apoptotic : CK(10028) : AC(7756)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Apoptotic, CURCUMIN : CK(25) : AC(18), Glioma

Delta-tocotrienol inhibits pancreatic cancer stem-like cells and prevents pancreatic cancer metastasis.

Article Published Date : May 08, 2017
Study Type : In Vitro Study
Additional Links
Substances : Tocotrienol: Delta : CK(74) : AC(33), Vitamin E : CK(3113) : AC(584)
Diseases : Pancreatic Cancer : CK(1574) : AC(584)
Pharmacological Actions : Anti-metastatic : CK(3007) : AC(2281), Antiproliferative : CK(10597) : AC(7939), Chemopreventive : CK(6660) : AC(2209)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Cancer Stem Cells : CK(507) : AC(370), Chemopreventive, Pancreatic Cancer : CK(2) : AC(2), Tocotrienol: Delta, VITAMIN E

Garcinone E exerts anticancer activities by inducing apoptosis and suppressing migration and invasion in ovarian cancer cells.

Article Published Date : Sep 05, 2017
Study Type : In Vitro Study
Additional Links
Substances : Garcinia Mangostana : CK(22) : AC(13)
Diseases : Ovarian Cancer : CK(1049) : AC(526)
Pharmacological Actions : Anti-metastatic : CK(3007) : AC(2281), Apoptotic : CK(10028) : AC(7756), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(978) : AC(609), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(1190) : AC(745)
Additional Keywords : Anti-metastatic, Apoptotic, Garcinia Mangostana, ovarian cancer

Genistein inhibits the growth and regulates the migration and invasion abilities of melanoma.

Article Published Date : Mar 27, 2017
Study Type : In Vitro Study
Additional Links
Substances : Genistein : CK(949) : AC(437)
Diseases : Melanoma : CK(979) : AC(578)
Pharmacological Actions : Anti-metastatic : CK(3007) : AC(2281)
Additional Keywords : Anti-metastatic, Genistein, melanoma

Ginsenoside Rb1 may be a potential therapeutic candidate for the treatment of ovarian cancer.

Article Published Date : Sep 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides : CK(2648) : AC(1456)
Diseases : Ovarian Cancer : CK(1049) : AC(526)
Pharmacological Actions : Anti-metastatic : CK(3007) : AC(2281)
Additional Keywords : Anti-metastatic, Ginsenosides, ovarian cancer

Hesperidin inhibited the migratory and invasive capabilities of A549 human non-small cell lung cancer cells.

Article Published Date : Mar 27, 2018
Study Type : In Vitro Study
Additional Links
Substances : Hesperidin : CK(1002) : AC(381)
Diseases : Non-Small-Cell Lung Carcinoma : CK(97) : AC(71)
Pharmacological Actions : Anti-metastatic : CK(3007) : AC(2281), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(1190) : AC(745)
Additional Keywords : Anti-metastatic, Hesperidin, Matrix metalloproteinase-9 (MMP-9) inhibitor, Non-Small-Cell Lung Carcinoma

Increase in motility and invasiveness of MCF7 cancer cells induced by nicotine is abolished by melatonin.

Article Published Date : Jan 15, 2018
Study Type : In Vitro Study
Additional Links
Substances : Melatonin : CK(2954) : AC(923)
Diseases : Breast Cancer : CK(8502) : AC(3150), Nicotine/Tobacco Toxicity : CK(276) : AC(110)
Pharmacological Actions : Anti-metastatic : CK(3007) : AC(2281)
Additional Keywords : Anti-metastatic, Breast Cancer : CK(113) : AC(34), melatonin, Nicotine/Tobacco Toxicity

Puerarin can inhibit the adhesion, invasion and migration of oophoroma HO-8910 cells.

Article Published Date : Jun 30, 2009
Study Type : In Vitro Study
Additional Links
Substances : Puerarin : CK(777) : AC(388)
Diseases : Cancer Metastasis : CK(986) : AC(559), Ovarian Cancer : CK(1049) : AC(526)
Pharmacological Actions : Anti-metastatic : CK(3007) : AC(2281)
Additional Keywords : Anti-metastatic, Cancer Metastasis, ovarian cancer, Puerarin

Resveratrol prevents endothelial cells injury in high-dose interleukin-2 therapy against melanoma.

Article Published Date : Dec 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol : CK(3298) : AC(1545)
Diseases : Lung Cancer : CK(3164) : AC(1486), Melanoma : CK(979) : AC(578)
Pharmacological Actions : Anti-metastatic : CK(3007) : AC(2281), Chemoprotective Agents : CK(4494) : AC(1716), Chemosensitizer : CK(1735) : AC(1325)
Additional Keywords : Anti-metastatic, Chemoprotective Agents, Chemosensitizer, lung cancer, melanoma, RESVERATROL

Shikonin and temozolomide may constitute a powerful new tool for Glioblastoma treatment by reducing therapy resistance and tumor recurrence.

Article Published Date : Apr 10, 2017
Study Type : Human In Vitro
Additional Links
Substances : Shikonin : CK(369) : AC(261)
Diseases : Glioblastoma : CK(746) : AC(418)
Pharmacological Actions : Anti-metastatic : CK(3007) : AC(2281), Antiproliferative : CK(10597) : AC(7939), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(978) : AC(609), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(1190) : AC(745)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Chemotherapeutic Synergy: Temozolomide : CK(67) : AC(51), Glioblastoma, Shikonin

The cytotoxic effects of the Stanley and Fortress onion varieties were strongest among the selected cultivars.

Article Published Date : May 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Onion : CK(511) : AC(151)
Diseases : Colorectal Cancer : CK(5061) : AC(2377)
Pharmacological Actions : Anti-metastatic : CK(3007) : AC(2281), Antiproliferative : CK(10597) : AC(7939)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), COLORECTAL CANCER, Cultivars : CK(12) : AC(10), Onion

These findings provide new insights into the antimetastatic mechanism of baicalein.

Article Published Date : Nov 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Baicalein : CK(370) : AC(242)
Diseases : Breast Cancer: Triple Negative : CK(1009) : AC(693)
Pharmacological Actions : Anti-metastatic : CK(3007) : AC(2281)
Additional Keywords : Anti-metastatic, Baicalein, Breast Cancer: Triple Negative

These findings suggested that betulinic acid might be a potential agent for inhibiting the growth and metastasis of breast cancer.

Article Published Date : Jan 08, 2018
Study Type : In Vitro Study
Additional Links
Substances : Betulinic acid : CK(292) : AC(203)
Diseases : Breast Cancer : CK(8502) : AC(3150)
Pharmacological Actions : Anti-metastatic : CK(3007) : AC(2281), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(1190) : AC(745)
Additional Keywords : Anti-metastatic, Betulinic acid, Breast Cancer : CK(113) : AC(34), Matrix metalloproteinase-9 (MMP-9) inhibitor

This is the first report suggesting selective anti-proliferative and anti-metastatic attributes of papaya leaf juice extract against prostatic diseases.

Article Published Date : Feb 25, 2017
Study Type : In Vitro Study
Additional Links
Substances : Papaya : CK(309) : AC(125)
Diseases : Prostate Cancer : CK(2886) : AC(1084), Prostatic Hyperplasia: Benign : CK(603) : AC(151)
Pharmacological Actions : Anti-metastatic : CK(3007) : AC(2281), Antiproliferative : CK(10597) : AC(7939)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Papaya, prostate cancer, Prostatic Hyperplasia: Benign, Selective Antiproliferation : CK(48) : AC(41)

This study demonstrates the anti-metastatic and anti-EMT activities of Antrodia camphorate.

Article Published Date : Aug 16, 2017
Study Type : In Vitro Study
Additional Links
Substances : Antrodia camphorata : CK(52) : AC(33)
Diseases : Colon Cancer : CK(1958) : AC(1228)
Pharmacological Actions : Anti-metastatic : CK(3007) : AC(2281), Antineoplastic Agents : CK(2365) : AC(1575), Antiproliferative : CK(10597) : AC(7939), Chemopreventive : CK(6660) : AC(2209)
Additional Keywords : Anti-metastatic, Antineoplastic Agents : CK(78) : AC(35), Antiproliferative : CK(75) : AC(61), Antrodia camphorata, Chemopreventive, COLON CANCER

Thymoquinone inhibits the migration and invasion of cervical cancer cells.

Article Published Date : Dec 03, 2017
Study Type : In Vitro Study
Additional Links
Substances : Thymoquinone : CK(1203) : AC(706)
Diseases : Cervical Cancer : CK(1010) : AC(619)
Pharmacological Actions : Anti-metastatic : CK(3007) : AC(2281)
Additional Keywords : Anti-metastatic, Cervical Cancer, thymoquinone

Vitamin K2 may be a potential therapeutic agent in the treatment of prostate cancer.

Article Published Date : Dec 31, 2012
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitamin K2 : CK(560) : AC(91)
Diseases : Prostate Cancer : CK(2886) : AC(1084)
Pharmacological Actions : Angiogenesis Inhibitors : CK(748) : AC(499), Anti-Inflammatory Agents : CK(42432) : AC(16960), Anti-metastatic : CK(3007) : AC(2281), Apoptotic : CK(10028) : AC(7756), NF-kappaB Inhibitor : CK(6338) : AC(3672)
Additional Keywords : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Anti-metastatic, Apoptotic, NF-kappaB Inhibitor, prostate cancer, Vitamin K2 : CK(16) : AC(6)

Withaferin A directly inhibits the proliferation and metastatic activity of gastric cancer cells.

Article Published Date : Jun 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Ashwagandha : CK(804) : AC(323)
Diseases : Gastric Cancer : CK(1667) : AC(758)
Pharmacological Actions : Anti-metastatic : CK(3007) : AC(2281), Antiproliferative : CK(10597) : AC(7939), Apoptotic : CK(10028) : AC(7756), Cell cycle arrest : CK(2198) : AC(1786)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Apoptotic, Ashwagandha, Cell cycle arrest, gastric cancer

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