Results for Anti-metastatic

A comprehensive review on anticancer mechanisms of crocin.

Article Published Date : Jul 02, 2017
Study Type : Review
Additional Links
Substances : Crocin : CK(731) : AC(310)
Diseases : Cancers: All : CK(35914) : AC(14179)
Pharmacological Actions : Anti-metastatic : CK(2843) : AC(2161), Antiproliferative : CK(9855) : AC(7389), Apoptotic : CK(9480) : AC(7298), Chemotherapeutic : CK(4271) : AC(1595), Telomerase Inhibitor : CK(98) : AC(65)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Apoptotic, Cancers: All, Chemotherapeutic, Crocin, Telomerase Inhibitor

A polysaccharide from Punica granatum has an inhibitory effect on metastasis.

Article Published Date : May 24, 2017
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1779) : AC(570)
Diseases : Cancer Metastasis : CK(949) : AC(535), Lung Cancer: Metastatic : CK(52) : AC(21)
Pharmacological Actions : Anti-metastatic : CK(2843) : AC(2161)
Additional Keywords : Anti-metastatic, Cancer Metastasis, Lung Cancer: Metastatic, pomegranate

A review of the multiple targets and signalling pathways of ginsenosides in cancers.

Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Ginsenosides : CK(2640) : AC(1452)
Diseases : Cancers: All : CK(35914) : AC(14179)
Pharmacological Actions : Anti-Inflammatory Agents : CK(38490) : AC(15393), Anti-metastatic : CK(2843) : AC(2161), Antiproliferative : CK(9855) : AC(7389), Cell cycle arrest : CK(2111) : AC(1706)
Additional Keywords : Anti-Inflammatory Agents, Anti-metastatic, Antiproliferative : CK(75) : AC(61), Cancers: All, Cell cycle arrest, Ginsenosides

An extract of Litchi seed has potential for development into a safe and potent alternative therapy for prostate cancer patients.

Article Published Date : Jan 29, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Litchi : CK(35) : AC(23)
Diseases : Prostate Cancer : CK(2772) : AC(1034)
Pharmacological Actions : Anti-metastatic : CK(2843) : AC(2161), Apoptotic : CK(9480) : AC(7298), Cell cycle arrest : CK(2111) : AC(1706), P21 Activation : CK(206) : AC(144)
Additional Keywords : Anti-metastatic, Apoptotic, Cell cycle arrest, Litchi, P21 Activation, Plant Extracts : CK(18617) : AC(6734), prostate cancer

Curcumin exerts its tumor suppressive function via inhibition of NEDD4 oncoprotein in glioma cancer cells.

Article Published Date : Jun 07, 2017
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(7066) : AC(3242)
Diseases : Glioma : CK(669) : AC(304)
Pharmacological Actions : Anti-metastatic : CK(2843) : AC(2161), Antiproliferative : CK(9855) : AC(7389), Apoptotic : CK(9480) : AC(7298)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Apoptotic, CURCUMIN : CK(25) : AC(18), Glioma

Delta-tocotrienol inhibits pancreatic cancer stem-like cells and prevents pancreatic cancer metastasis.

Article Published Date : May 08, 2017
Study Type : In Vitro Study
Additional Links
Substances : Tocotrienol: Delta : CK(74) : AC(33), Vitamin E : CK(3039) : AC(570)
Diseases : Pancreatic Cancer : CK(1544) : AC(561)
Pharmacological Actions : Anti-metastatic : CK(2843) : AC(2161), Antiproliferative : CK(9855) : AC(7389), Chemopreventive : CK(6496) : AC(2135)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Cancer Stem Cells : CK(501) : AC(365), Chemopreventive, Pancreatic Cancer : CK(2) : AC(2), Tocotrienol: Delta, VITAMIN E

Garcinone E exerts anticancer activities by inducing apoptosis and suppressing migration and invasion in ovarian cancer cells.

Article Published Date : Sep 05, 2017
Study Type : In Vitro Study
Additional Links
Substances : Garcinia Mangostana : CK(22) : AC(13)
Diseases : Ovarian Cancer : CK(1021) : AC(503)
Pharmacological Actions : Anti-metastatic : CK(2843) : AC(2161), Apoptotic : CK(9480) : AC(7298), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(936) : AC(583), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(1118) : AC(706)
Additional Keywords : Anti-metastatic, Apoptotic, Garcinia Mangostana, ovarian cancer

Genistein inhibits the growth and regulates the migration and invasion abilities of melanoma.

Article Published Date : Mar 27, 2017
Study Type : In Vitro Study
Additional Links
Substances : Genistein : CK(932) : AC(431)
Diseases : Melanoma : CK(913) : AC(544)
Pharmacological Actions : Anti-metastatic : CK(2843) : AC(2161)
Additional Keywords : Anti-metastatic, Genistein, melanoma

Ginsenoside Rb1 may be a potential therapeutic candidate for the treatment of ovarian cancer.

Article Published Date : Sep 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides : CK(2640) : AC(1452)
Diseases : Ovarian Cancer : CK(1021) : AC(503)
Pharmacological Actions : Anti-metastatic : CK(2843) : AC(2161)
Additional Keywords : Anti-metastatic, Ginsenosides, ovarian cancer

Hesperidin inhibited the migratory and invasive capabilities of A549 human non-small cell lung cancer cells.

Article Published Date : Mar 27, 2018
Study Type : In Vitro Study
Additional Links
Substances : Hesperidin : CK(950) : AC(358)
Diseases : Non-Small-Cell Lung Carcinoma : CK(85) : AC(61)
Pharmacological Actions : Anti-metastatic : CK(2843) : AC(2161), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(1118) : AC(706)
Additional Keywords : Anti-metastatic, Hesperidin, Matrix metalloproteinase-9 (MMP-9) inhibitor, Non-Small-Cell Lung Carcinoma

Increase in motility and invasiveness of MCF7 cancer cells induced by nicotine is abolished by melatonin.

Article Published Date : Jan 15, 2018
Study Type : In Vitro Study
Additional Links
Substances : Melatonin : CK(2861) : AC(908)
Diseases : Breast Cancer : CK(8185) : AC(3005), Nicotine/Tobacco Toxicity : CK(273) : AC(108)
Pharmacological Actions : Anti-metastatic : CK(2843) : AC(2161)
Additional Keywords : Anti-metastatic, Breast Cancer : CK(113) : AC(34), melatonin, Nicotine/Tobacco Toxicity

Puerarin can inhibit the adhesion, invasion and migration of oophoroma HO-8910 cells.

Article Published Date : Jun 30, 2009
Study Type : In Vitro Study
Additional Links
Substances : Puerarin : CK(777) : AC(388)
Diseases : Cancer Metastasis : CK(949) : AC(535), Ovarian Cancer : CK(1021) : AC(503)
Pharmacological Actions : Anti-metastatic : CK(2843) : AC(2161)
Additional Keywords : Anti-metastatic, Cancer Metastasis, ovarian cancer, Puerarin

Resveratrol prevents endothelial cells injury in high-dose interleukin-2 therapy against melanoma.

Article Published Date : Dec 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol : CK(3218) : AC(1507)
Diseases : Lung Cancer : CK(3014) : AC(1409), Melanoma : CK(913) : AC(544)
Pharmacological Actions : Anti-metastatic : CK(2843) : AC(2161), Chemoprotective Agents : CK(4209) : AC(1597), Chemosensitizer : CK(1636) : AC(1259)
Additional Keywords : Anti-metastatic, Chemoprotective Agents, Chemosensitizer, lung cancer, melanoma, RESVERATROL

Shikonin and temozolomide may constitute a powerful new tool for Glioblastoma treatment by reducing therapy resistance and tumor recurrence.

Article Published Date : Apr 10, 2017
Study Type : Human In Vitro
Additional Links
Substances : Shikonin : CK(369) : AC(261)
Diseases : Glioblastoma : CK(703) : AC(390)
Pharmacological Actions : Anti-metastatic : CK(2843) : AC(2161), Antiproliferative : CK(9855) : AC(7389), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(936) : AC(583), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(1118) : AC(706)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Chemotherapeutic Synergy: Temozolomide : CK(65) : AC(49), Glioblastoma, Shikonin

The cytotoxic effects of the Stanley and Fortress onion varieties were strongest among the selected cultivars.

Article Published Date : May 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Onion : CK(511) : AC(151)
Diseases : Colorectal Cancer : CK(4830) : AC(2248)
Pharmacological Actions : Anti-metastatic : CK(2843) : AC(2161), Antiproliferative : CK(9855) : AC(7389)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), COLORECTAL CANCER, Cultivars : CK(12) : AC(10), Onion

These findings provide new insights into the antimetastatic mechanism of baicalein.

Article Published Date : Nov 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Baicalein : CK(312) : AC(202)
Diseases : Breast Cancer: Triple Negative : CK(958) : AC(652)
Pharmacological Actions : Anti-metastatic : CK(2843) : AC(2161)
Additional Keywords : Anti-metastatic, Baicalein, Breast Cancer: Triple Negative

These findings suggested that betulinic acid might be a potential agent for inhibiting the growth and metastasis of breast cancer.

Article Published Date : Jan 08, 2018
Study Type : In Vitro Study
Additional Links
Substances : Betulinic acid : CK(254) : AC(178)
Diseases : Breast Cancer : CK(8185) : AC(3005)
Pharmacological Actions : Anti-metastatic : CK(2843) : AC(2161), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(1118) : AC(706)
Additional Keywords : Anti-metastatic, Betulinic acid, Breast Cancer : CK(113) : AC(34), Matrix metalloproteinase-9 (MMP-9) inhibitor

This is the first report suggesting selective anti-proliferative and anti-metastatic attributes of papaya leaf juice extract against prostatic diseases.

Article Published Date : Feb 25, 2017
Study Type : In Vitro Study
Additional Links
Substances : Papaya : CK(309) : AC(124)
Diseases : Prostate Cancer : CK(2772) : AC(1034), Prostatic Hyperplasia: Benign : CK(589) : AC(145)
Pharmacological Actions : Anti-metastatic : CK(2843) : AC(2161), Antiproliferative : CK(9855) : AC(7389)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Papaya, prostate cancer, Prostatic Hyperplasia: Benign, Selective Antiproliferation : CK(47) : AC(40)

This study demonstrates the anti-metastatic and anti-EMT activities of Antrodia camphorate.

Article Published Date : Aug 16, 2017
Study Type : In Vitro Study
Additional Links
Substances : Antrodia camphorata : CK(52) : AC(33)
Diseases : Colon Cancer : CK(1903) : AC(1192)
Pharmacological Actions : Anti-metastatic : CK(2843) : AC(2161), Antineoplastic Agents : CK(2221) : AC(1456), Antiproliferative : CK(9855) : AC(7389), Chemopreventive : CK(6496) : AC(2135)
Additional Keywords : Anti-metastatic, Antineoplastic Agents : CK(78) : AC(35), Antiproliferative : CK(75) : AC(61), Antrodia camphorata, Chemopreventive, COLON CANCER

Thymoquinone inhibits the migration and invasion of cervical cancer cells.

Article Published Date : Dec 03, 2017
Study Type : In Vitro Study
Additional Links
Substances : Thymoquinone : CK(1178) : AC(692)
Diseases : Cervical Cancer : CK(968) : AC(588)
Pharmacological Actions : Anti-metastatic : CK(2843) : AC(2161)
Additional Keywords : Anti-metastatic, Cervical Cancer, thymoquinone

Vitamin K2 may be a potential therapeutic agent in the treatment of prostate cancer.

Article Published Date : Dec 31, 2012
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitamin K2 : CK(560) : AC(91)
Diseases : Prostate Cancer : CK(2772) : AC(1034)
Pharmacological Actions : Angiogenesis Inhibitors : CK(716) : AC(476), Anti-Inflammatory Agents : CK(38490) : AC(15393), Anti-metastatic : CK(2843) : AC(2161), Apoptotic : CK(9480) : AC(7298), NF-kappaB Inhibitor : CK(5828) : AC(3391)
Additional Keywords : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Anti-metastatic, Apoptotic, NF-kappaB Inhibitor, prostate cancer, Vitamin K2 : CK(16) : AC(6)

Withaferin A directly inhibits the proliferation and metastatic activity of gastric cancer cells.

Article Published Date : Jun 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Ashwagandha : CK(748) : AC(301)
Diseases : Gastric Cancer : CK(1611) : AC(719)
Pharmacological Actions : Anti-metastatic : CK(2843) : AC(2161), Antiproliferative : CK(9855) : AC(7389), Apoptotic : CK(9480) : AC(7298), Cell cycle arrest : CK(2111) : AC(1706)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(75) : AC(61), Apoptotic, Ashwagandha, Cell cycle arrest, gastric cancer

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