Vitamin D in hypothyroid patients and association between vitamin D and anti-TPO in autoimmune hypothyroidism. - GreenMedInfo Summary
Vitamin D in Hypothyroid Patients and Association between Vitamin D and Anti-TPO in Autoimmune Hypothyroidism.
Clin Lab. 2020 Aug 1 ;66(8). PMID: 32781825
Sabira Dabeer
BACKGROUND: To find out the incidence of vitamin D deficiency in autoimmune hypothyroidism and the correlation between vitamin D and anti-TPO antibodies.
METHODS: This observational study was undertaken in the Biochemistry Department of ESI-PGIMSR&Model Hospital Andheri Mumbai from March 2015 to September 2015. Vitamin D and anti-TPO levels of 101 known cases of hypothyroidism were measured on a Cobas e411. Patients included were between 20 and 50 years old with 63 females and 38 males.
RESULTS: Twenty-two of 101 patients were anti-TPO positive with a mean vitamin D level 10.86± 5.91 and mean anti-TPO 59.45 ± 12.46. A negative correlation of r = -0.4949 was found between vitamin D and anti-TPO in patients with anti-TPO positive hypothyroidism.
CONCLUSIONS: Low vitamin D levels were found in hypothyroid patients with severe deficiency seen in anti-TPO positive cases.
