Topical treatment of tinea pedis using 6% coriander oil in unguentum leniens. - GreenMedInfo Summary

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Abstract Title:

Topical treatment of tinea pedis using 6% coriander oil in unguentum leniens: a randomized, controlled, comparative pilot study.

Abstract Source:

Dermatology. 2013 ;226(1):47-51. Epub 2013 Mar 1. PMID: 23466353

Abstract Author(s):

F C Beikert, Z Anastasiadou, B Fritzen, U Frank, M Augustin

Article Affiliation:

F C Beikert

Abstract:

BACKGROUND: The antifungal activity of coriander oil has already been demonstrated in vitro.

OBJECTIVE: Evaluation of the efficacy and tolerability of 6% coriander oil in unguentum leniens in the treatment of interdigital tinea pedis.

METHODS: Half-side comparative pilot study on subjects with symmetric, bilateral interdigital tinea pedis. Active drug and placebo control were applied twice daily on the affected areas, and follow-up visits were performed on days 14 and 28.

RESULTS: 40 participants (mean age 52.5 years, 60% male) were included in the study. For 6% coriander oil in unguentum leniens, a highly significant improvement of the clinical signs (p<0.0001) was observed during the entire observation period; the number of positive fungal cultures also tended to decrease (p = 0.0654). The tolerability of the tested substances was good.

CONCLUSION: Coriander oil is effective and well tolerated in the treatment of interdigital tinea pedis.

Article Published Date : Dec 31, 2012
Study Type : Human Study
Additional Links
Substances : Coriandor : CK(14) : AC(5)
Diseases : Tinea Pedis : CK(31) : AC(4)
Pharmacological Actions : Antifungal Agents : CK(730) : AC(422)
Additional Keywords : Phytotherapy : CK(4003) : AC(1031)

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Key Research Topics

Disease

Tinea Pedis

Pharmacological Actions

Antifungal Agents

Substance

Coriandor

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