Abstract Title:

Effect of royal jelly on bisphenol A-induced proliferation of human breast cancer cells.

Abstract Source:

Biosci Biotechnol Biochem. 2007 Jan;71(1):253-5. Epub 2007 Jan 7. PMID:17213647

Abstract Author(s):

Mako Nakaya, Hiroyuki Onda, Kyoko Sasaki, Akiko Yukiyoshi, Hirofumi Tachibana, Koji Yamada


Royal jelly is known as a functional food containing many useful minerals. In this study, we found an anti-environmental estrogen activity of royal jelly. Bisphenol A (BPA) is an environmental estrogen that stimulates proliferation of human breast cancer MCF-7 cells. Royal jelly inhibited the growth-promoting effect of BPA on MCF-7 cells, even though it did not affect the proliferation of cells in the absence of BPA. In addition, this inhibiting effect of royal jelly was heat-stable.

Study Type : In Vitro Study

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